46th week of 2014 patent applcation highlights part 51 |
Patent application number | Title | Published |
20140336385 | TRIAZOLIUM AND TETRAZOLIUM DERIVATIVES AS ORGANIC LIGHT EMITTERS - Provided herein are organic compounds useful in a variety of OLED applications. | 2014-11-13 |
20140336386 | FORMULATIONS PHARMACOKINETICS OF DEUTERATED BENZOQUINOLINE INHIBITORS OF VESICULAR MONOAMINE TRANSPORTER 2 - The present invention relates to new pharmaceutical compositions comprising benzoquinoline compounds, and methods to inhibit vesicular monoamine transporter 2 (VMAT2) activity in a subject for the treatment of chronic hyperkinetic movement disorders. | 2014-11-13 |
20140336387 | SYNTHESIS OF DEUTERATED CATECHOLS AND BENZO[D][1,3]DIOXOLES AND DERIVATIVES THEREOF - The present invention provides a convenient and efficient process for the synthesis of d | 2014-11-13 |
20140336388 | Nitrofurfuryl Substituted Phenyl Linked Piperidino-Oxadiazoline Conjugates As Anti-Tubercular Agents And Process For The Preparation Thereof - The present invention provides nitrofurfuryl substituted phenyl linked piperidino-oxadiazolone compounds of general formula (A) as anti-tubercular agents; wherein G=formula (B); X═H, F; R═H, CH | 2014-11-13 |
20140336389 | METHOD FOR MANUFACTURING 4-BENZYL-1-METHYL-6-OXABICYCLO[3,2,0]HEPTANE DERIVATIVE AND METHOD FOR MANUFACTURING AZOLE DERIVATIVE - In order to manufacture a higher yield of a 4-benzyl-1-methyl-6-oxabicyclo[3,2,0]heptane derivative, the present invention is a method for manufacturing a compound represented by General Formula (I) which includes a step for reducing a compound represented by General Formula (II) using a hydride-type reducing agent in an aprotic solvent having an amide bond. | 2014-11-13 |
20140336390 | SYNTHETIC METHODS FOR SPIRO-OXINDOLE COMPOUNDS - This invention is directed to methods of preparing certain spiro-oxindole derivatives, which are useful for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain. | 2014-11-13 |
20140336391 | PROCESS FOR THE PREPARATION OF ASENAPINE INTERMEDIATE - The present invention provides a process for the preparation of the asenapine intermediate of Formula (III) using a magnesium-methanol-acetic acid mixture. | 2014-11-13 |
20140336392 | NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME - The present invention relates to a novel organic electroluminescent compound and an organic electroluminescent device containing the same. Using the organic electroluminescent compounds of the present invention, it is possible to manufacture an OLED device with a long operating lifespan and high luminous efficiency. In addition, the compounds can improve the power efficiency of the device and reduce overall power consumption. | 2014-11-13 |
20140336393 | PROCESS FOR PREPARING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR - The present invention relates to processes for preparing solid state forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide, including Compound 1 Form A, Compound 1 Form A-HCl, Compound 1 Form B, and Compound 1 Form B-HCl, any combination of these forms, pharmaceutical compositions thereof, and methods of treatment therewith. | 2014-11-13 |
20140336394 | EMM-23 Molecular Sieve Materials, Its Synthesis and Use - A new molecular sieve material is designated as EMM-23 and has, in its as-calcined form, an X-ray diffraction pattern including the following peaks in Table 1: | 2014-11-13 |
20140336395 | Salt forms of [R-(R*,R*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-p- henyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid - Novel salt forms of [R—(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid characterized by their X-ray powder diffraction pattern and solid-state NMR spectra are described, as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia, and Alzheimer's Disease. | 2014-11-13 |
20140336396 | N-HYDROXYLSULFONAMIDE DERIVATIVES AS NEW PHYSIOLOGICALLY USEFUL NITROXYL DONORS - The invention relates to N-hydroxysulfonamide derivatives that donate nitroxyl (HNO) under physiological conditions and are useful in treating and/or preventing the onset and/or development of diseases or conditions that are responsive to nitroxyl therapy, including heart failure and ischemia/reperfusion injury. Novel N-hydroxysulfonamide derivatives release NHO at a controlled rate under physiological conditions, and the rate of HNO release is modulated by varying the nature and location of functional groups on the N-hydroxysulfonamide derivatives. | 2014-11-13 |
20140336397 | METHODS FOR THE SYNTHESIS OF 13C LABELED DHA AND USE AS A REFERENCE STANDARD - A method for preparing | 2014-11-13 |
20140336398 | METHODS OF REFINING AND PRODUCING FUEL AND SPECIALTY CHEMICALS FROM NATURAL OIL FEEDSTOCKS - Methods are provided for refining natural oil feedstocks. The methods include reacting the feedstock with a low-molecular-weight olefin or mid-weight olefin in the presence of a metathesis catalyst under conditions sufficient to form a metathesized product including olefins and esters. In certain embodiments, the methods further include separating the olefins from the esters in the metathesized product. In certain embodiments, the methods further include transesterifying the esters in the presence of an alcohol to form a transesterified product. | 2014-11-13 |
20140336399 | Methods of Refining and Producing Fuel and Specialty Chemicals from Natural Oil Feedstocks - Methods are provided for refining natural oil feedstocks. The methods include reacting the feedstock with a molar excess of low-molecular-weight olefins in the presence of a metathesis catalyst. In certain embodiments, the methods further include separating at least a portion of the unreacted low-molecular-weight olefins. In certain embodiments, the methods further include recycling the separated unreacted low-molecular-weight olefins. | 2014-11-13 |
20140336400 | CHROMATOGRAPHIC PROCESS FOR THE PRODUCTION OF HIGHLY PURIFIED POLYUNSATURATED FATTY ACIDS - A process is provided for recovering a first polyunsaturated fatty acid (PUFA) from a feed mixture including at least one additional fatty acid (e.g., a second fatty acid (FA)). The process optionally comprises:
| 2014-11-13 |
20140336401 | Manufacturing Method For Organopolysiloxane-Polyoxyalkylene Block Copolymer - The present invention relates to a manufacturing method for an organopolysiloxane-polyoxyalkylene block copolymer obtained by condensation reaction of a polyoxyalkylene compound having a particular chemical structure and an organopolysiloxane having a particular chemical structure. The manufacturing method according to the present invention can enable an easy manufacturing of a high molecular weight organopolysiloxane-polyoxyalkylene block copolymer and provide an organopolysiloxane-polyoxyalkylene block copolymer where an amount of volatile cyclic polysiloxane produced as a by-product is small. | 2014-11-13 |
20140336402 | LIGAND FORMING ASYMMETRICAL TRANSFORMATION CATALYST FOR MAKING NEW PHARMACEUTICALS - The present invention provides a catalyst complex or ligand, and compositions thereof, for use in a variety of organic reactions having high reactivity and enantioselectivity. The catalyst is a N-heterocyclic carbene having three fused rings with first and second rings being six-membered rings and the third being a five-membered ring. The first ring is fused to the second and has four substituents. The second ring has two nitrogens flanking a carbene atom with one nitrogen bound to a substituent. The carbene atom may optionally be bonded to a metal. The third ring is fused to the second ring and contains two nitrogens. The third ring of the catalyst has a double bond and two substituents on adjacent non-fused carbons. A non-fused nitrogen of the third ring is partially bonded to another substituent. Methods for the synthesis and use of the catalyst embodiments of the present invention are also provided. | 2014-11-13 |
20140336403 | PROCESS - A process for the preparation of a compound of formula (I): | 2014-11-13 |
20140336404 | METHOD FOR PRODUCING PENTAFLUOROSULFANYL BENZOIC ACID - Provided is a simple, safe, and industrially practical method for producing a pentafluorosulfanylbenzoic acid. | 2014-11-13 |
20140336405 | Process for preparing spiro[2.5]octane-5,7-dione - Disclosed is a method for the synthesis of spiro[2.5]octane-5,7-dione useful as intermediate in the manufacture of pharmaceutically active ingredients. Also disclosed are novel intermediates used in the synthesis of this compound. | 2014-11-13 |
20140336406 | SYNTHESIS OF METAL ALKOXIDES - A process for preparing metal alkoxides starting with a metal chloride and esters of either succinic acid or glutaric acid to produce metal alkoxide, an acid anhydride and alkyl chloride. Esterification of the acid anhydride with alcohol regenerates the ester of organic acid. The first step is carried out under anhydrous conditions. By regenerating the organic acid esters in the process, the only byproduct is an alkyl chloride. | 2014-11-13 |
20140336407 | INTEGRATED SYSTEM TECHNIQUE FOR COUPLING FIXED BED AND JET FLUIDIZED BED TO SEPARATOR UNIT - A process of integrated system formed by coupling of fixed bed, jetting floating bed, and separating unit, aimed to provide a new process and equipment of higher efficiency, which integrates multi-type reactors and separation is provided. Reaction materials undergo preliminary reaction in fixed bed reactor and intensified reaction in jetting floating bed reactor, and then separation in the subsequent separation system. Unreacted materials will be returned to the raw material intermediate storage tank for mixing with fresh materials, as raw materials for continued reaction. During this process, materials first pass the fixed bed reactor once to achieve certain conversion rate, and then enter the jetting floating bed reactor for intensified reaction. When the product reaches required concentration, the materials will enter subsequent separation equipment for separation. | 2014-11-13 |
20140336408 | PROCESS FOR THE MANUFACTURE OF ALKYLAMINO ALKYLENE PHOSPHONIC ACIDS - A process for the manufacture of alkylamino alkylene phosphonic acids is disclosed. In detail, a specific phosphonate is reacted with an agent selected to yield an alkylamino moiety substituted by a radical selected from OH, OR', NH | 2014-11-13 |
20140336409 | PROCESS FOR PREPARING AN INTERNAL OLEFIN SULFONATE - The invention relates to a process for preparing an internal olefin sulfonate, comprising sulfonating an internal olefin into sulfonated internal olefin followed by contacting sulfonated internal olefin with a base containing solution, wherein the molar ratio of internal olefin to solvent for the base is higher than 0.06. Further, the invention relates to an internal olefin sulfonate obtainable by said process. | 2014-11-13 |
20140336410 | ETHYLENICALLY UNSATURATED MONOMERS HAVING CHELATING FUNCTIONALITY - The present invention provides novel polymerizable monomers having chelating functionality and processes to make them. In particular, the novel monomers are vinyl aminocarboxylates and are prepared by reacting iminodiacetic acid, iminodisuccinic acid, or a salt thereof and a vinyl epoxy benzene monomer. | 2014-11-13 |
20140336411 | CATALYST FOR THE OXIDATION OF HYDROCARBONS CONSISTING OF MOLYBDENUM, VANADIUM, NIOBIUM, TELLURIUM, MANGANESE AND COBALT - A catalyst material for the oxidation and/or oxidative dehydrogenation of hydrocarbons, in particular for the selective oxidation of propane to acrylic acid, comprising a) molybdenum (Mo), b) vanadium (V), c) niobium (Nb), d) tellurium (Te), e) manganese (Mn) and cobalt, in which the molar ratio of at least one element, which is selected from manganese and cobalt, to molybdenum lies in the range 0.01 to 0.2. Furthermore, a catalyst for the oxidation and/or oxidative dehydrogenation of hydrocarbons, a use of the catalyst material or of the catalyst, a method for producing a catalyst material for the oxidation and/or oxidative dehydrogenation of hydrocarbons, and a method for the selective oxidation of propane to acrylic acid. | 2014-11-13 |
20140336412 | PROCESS FOR THE PREPARATION OF GAMMA AMINO ACIDS AND INTERMEDIATES USED IN SAID PROCESS - The invention relates to the preparation of gamma amino acids of formula (I) and pharmaceutically acceptable salts, solvates and prodrugs thereof, and to intermediates used for their preparation. (formula I) wherein R | 2014-11-13 |
20140336413 | Novel Crystalline Polymorphs of Acetyl-Glycine-Beta-Alanine and Process of Making the Same - This invention discloses novel crystalline polymorphs of acetyl-glycine-beta-alanine and process of making the same. The mentioned crystalline polymorphs can exhibit excellent purity and storage stability according to this invention. Therefore, the mentioned crystalline polymorphs can be applied in topical cosmetic compositions, pharmaceutical compositions as skin care preparations, or other functional preparations. | 2014-11-13 |
20140336414 | LIQUID CRYSTALLINE COMPOUND AND ELECTROLYTE MATERIAL - A liquid crystalline compound and an electrolyte material in which the conductivity switches between ion conductivity and non-ion conductivity depending on changes in temperature, and thus a switching function can be obtained are proposed. The liquid crystalline compound has a columnar liquid crystal phase in which an ammonium group is linked with an alkoxyphenyl group. A structural change thereof occurs depending on changes in temperature, and the conductivity switches between ion-conducting and non-ion-conducting, and thus the switching function can be obtained. | 2014-11-13 |
20140336415 | DIPHENYLAMINE COMPOUNDS AND PRODUCTION METHOD THEREOF - An inexpensive and convenient production method of diphenylamine compounds is provided, that can solve problems in the conventional technology such as decrease in reactivity, restriction of substituents, high temperature, high pressure, by-products or the like. Further, diphenylamine compounds useful as intermediates of medicine and agricultural chemicals are provided. Diphenylamine compounds are produced, represented by general formula (3): | 2014-11-13 |
20140336416 | METHOD FOR SYNTHESISING BIS[3-(N,N-DIALKYLAMINO)PROPYL]ETHERS - The invention relates to an improved method for synthesizing bis[3-(N,N-dialkylamino)propyl]ethers from acrylonitrile, comprising the following reactions:
| 2014-11-13 |
20140336417 | Oxidation of Cyclohexylbenzene - In a process for oxidizing cyclohexylbenzene, a composition comprising cyclohexylbenzene is contacted with oxygen in at least one oxidation zone under oxidation conditions sufficient to produce at least some (i) cyclohexylbenzene hydroperoxide; (ii) a first byproduct; and (iii) a second byproduct in an effluent. A ratio β is determined according to the following formula: | 2014-11-13 |
20140336418 | Production of Fuel from Chemicals Derived from Biomass - Hydrocarbons may be formed from six carbon sugars. This process involves obtaining a quantity of a hexose sugar. The hexose sugar may be derived from biomass. The hexose sugar is reacted to form an alkali metal levulinate, an alkali metal valerate, an alkali metal 5-hydroxy pentanoate, or an alkali metal 5-alkoxy pentanoate. An anolyte is then prepared for use in a electrolytic cell. The anolyte contains the alkali metal levulinate, the alkali metal valerate, the alkali metal 5-hydroxy pentanoate, or the alkali metal 5-alkoxy pentanoate. The anolyte is then decarboxylated. This decarboxylating operates to decarboxylate the alkali metal levulinate, the alkali metal valerate, the alkali metal 5-hydroxy pentanoate, or the alkali metal 5-alkoxy pentanoate to form radicals, wherein the radicals react to form a hydrocarbon fuel compound. | 2014-11-13 |
20140336419 | BIS(1,1-DICHLORO-3,3,3-TRIFLUOROPROPYL) ETHER AND PROCESS FOR PREPARING THE SAME - The present invention provides a symmetrical ether compound which is chlorinated in the α position and which is useful as an intermediate for medicine and pesticides and as a raw material or a synthetic intermediate for producing a fluorine-containing compound, in particular a bis(1,1-dichloro-3,3,3-trifluoropropyl)ether represented by formula [1] which is obtained by chlorinating a bis(3,3,3-trifluoropropyl)ether. This bis(1,1-dichloro-3,3,3-trifluoropropyl)ether is produced by chlorinating, preferably under ultraviolet light irradiation, a bis(3,3,3-trifluoropropyl)ether. | 2014-11-13 |
20140336420 | SYSTEM AND METHOD FOR PRODUCING GASOLINE OR DIMETHYL ETHER - A system or method for producing gasoline or dimethyl ether from natural gas via methanol includes: steam-reforming natural gas to generate reformed gas; synthesizing methanol from the reformed gas; synthesizing gasoline or dimethyl ether from the methanol; and at least one is selected from the group consisting of: pre-reforming natural gas prior to the steam-reforming; recovering carbon dioxide from flue gas generated in the steam-reforming; and preheating combustion air to be supplied to the steam-reforming by using synthesis heat generated in the synthesis of gasoline or dimethyl ether. In addition, an overall energy balance of the system is constructed by using heat recovery from flue gas generated in the steam-reforming, heat recovery from the reformed gas, synthesis heat generated in the synthesis of methanol, synthesis heat generated in the synthesis of gasoline or DME, and heat recovered in the pre-reforming, carbon dioxide recovering, or air preheating, respectively if selected. | 2014-11-13 |
20140336421 | Oregano Clonal Line Having High Levels of Carvacrol - A new and distinct clonal line of oregano named KI-Ov1750 and characterized by elevated levels of carvacrol and vigorous growth. | 2014-11-13 |
20140336422 | Process for Producing a Monocycloalkyl-Substituted Aromatic Compound - In a process for producing mono-cycloalkyl-substituted aromatic compound, benzene and cyclic monoolefin are contacted with a catalyst under alkylation conditions to produce an effluent containing mono-cycloalkyl-substituted aromatic compound. The catalyst comprises a molecular sieve. | 2014-11-13 |
20140336423 | PRODUCTION OF SATURATED FATTY ALCOHOLS FROM ENGINEERED MICROORGANISMS - Recombinant bacterial microorganisms are provided which comprise heterologous fatty acyl reductases (“FAR”) polypeptides wherein said microorganisms have been engineered to produce increased amounts of saturated fatty alcohols and methods of making saturated fatty alcohols using the recombinant bacterial microorganisms. | 2014-11-13 |
20140336424 | Method for Producing Trans-1-Chloro-3,3,3-Trifluoropropene - Provided is a method for producing trans-1-chloro-3,3,3-trifluoropropene usable as a raw material for a foaming agent for a hard polyurethane foam, a solvent, a cleaning agent, a cooling medium, a working fluid, a propellant, a fluorinated resin, etc., the method involving a step of bringing cis-1-chloro-3,3,3-trifluoropropene into contact with a catalyst, wherein the catalyst includes a fluorinated metal oxide or a metal fluoride each produced by applying a fluorination treatment to a metal oxide containing one kind or two or more kinds of metals and containing aluminum atoms that make up 50 at. % or more of metal atoms to thereby substitute some or all of oxygen atoms in the metal oxide with fluorine atom(s), wherein the fluorinated metal oxide or the metal fluoride is a compound produced through a drying treatment at 400 to 600° C. | 2014-11-13 |
20140336425 | PROCESS FOR THE PRODUCTION OF TETRACHLOROMETHANE - Processes for the production of tetrachloromethane are provided. The present processes involve catalyzing the chlorination of a feedstream comprising partially chlorinated methanes with a free radical initiator. Cost savings are thus provided relative to conventional processes that require the use of high temperatures and/or pressures, and safety concerns are alleviated or eliminated. | 2014-11-13 |
20140336426 | PROCESS AND APPARATUS FOR HEAT RECOVERY IN VINYL CHLORIDE MONOMER PLANTS OR IN INTEGRATED VINYL CHLORIDE MONOMER OR POLYVINYL CHLORIDE PLANTS - Disclosed is a process and apparatus for heat recovery in vinyl chloride monomer manufacturing plants or in integrated vinyl chloride monomer/polyvinyl chloride manufacturing plants. A process for capture and use of excess heat recovered in the production of vinyl chloride includes distillatively purifying DCE in a high-boilers column, using a heat exchanger to capture thermal energy from a purified DCE vapor stream from the high-boilers column, generating low pressure steam from the captured thermal energy, returning condensed DCE vapors to the high-boilers column, and heating parts of the plant with the generated low pressure steam. | 2014-11-13 |
20140336427 | METHODS OF AND APPARATUSES FOR UPGRADING A HYDROCARBON STREAM INCLUDING A DEOXYGENATED PYROLYSIS PRODUCT - Methods of and apparatuses for upgrading a hydrocarbon stream are provided. In an embodiment, a method of upgrading a hydrocarbon stream includes providing the hydrocarbon stream that includes a deoxygenated pyrolysis product. The hydrocarbon stream also includes a residual oxygen-containing compound content. The residual oxygen-containing compound content of the hydrocarbon stream is reduced to form an upgraded hydrocarbon stream. | 2014-11-13 |
20140336428 | RECYCLE GAS SCRUBBING USING IONIC LIQUIDS - A method of removing CO | 2014-11-13 |
20140336429 | HYDROGENATION OF AROMATICS AND OTHER UNSATURATED ORGANIC COMPOUNDS - The present invention relates to supported Ni-catalysts optionally comprising Zn as a promoter, methods for the production of said catalysts and uses of said catalysts for the hydrogenation of a hydrocarbon feed. | 2014-11-13 |
20140336430 | Alkylation Unit and Process - A process for producing alkylated hydrocarbons includes the steps of: (a) combining a first feed stream comprising an olefin and an isoparaffin with an alkylation catalyst stream in a first alkylation reactor, (b) removing heat of reaction from the first alkylation reactor, (c) passing an effluent of the first alkylation reactor to a first reaction zone of a second alkylation reactor operating adiabatically to thereby form a first reaction zone effluent, (d) passing the first reaction zone effluent to a second reaction zone of the second alkylation reactor for mixture with a second feed stream comprising an olefin and an isoparaffin, and (e) passing an effluent of the second alkylation reactor to a settler for separation into a hydrocarbon stream and an alkylation catalyst effluent stream. An alkylation unit for carrying out the process is also disclosed. | 2014-11-13 |
20140336431 | PROCESS FOR THE PRODUCTION OF ALKENES AND/OR AROMATIC COMPOUNDS - Processes for the production of alkenes are provided. The processes make use of methane as a low cost starting material. | 2014-11-13 |
20140336432 | SYNTHESIS OF OLEFINS FROM OXYGEN-FREE DIRECT CONVERSION OF METHANE AND CATALYSTS THEREOF - The present invention is related to the preparation of a metal lattice-doping catalyst in an amorphous molten state, and the process of catalyzing methane to make olefins, aromatics, and hydrogen using the catalyst under oxygen-free, continuous flowing conditions. Such a process has little coke deposition and realizes atom-economic conversion. Under the conditions encountered in a fixed bed reactor (i.e. reaction temperature: 750˜1200° C.; reaction pressure: atmospheric pressure; the weight hourly space velocity of feed gas: 1000˜30000 ml/g/h; and fixed bed), conversion of methane is 8-50%. The selectivity of olefins is 30˜90%. And selectivity of aromatics is 10˜70%. There is no coking. The reaction process has many advantages, including a long catalyst life (>100 hrs), high stability of redox and hydrothermal properties under high temperature, high selectivity towards target products, zero coke deposition, easy separation of products, good reproducibility, safe and reliable operation, etc., all of which are very desirable for industrial application. | 2014-11-13 |
20140336433 | PROCESS FOR INITIATING OPERATIONS OF A SEPARATION APPARATUS - One exemplary embodiment can be a process for initiating operations of a separation apparatus. The process may include passing a hydrocarbon carrier having a sulfiding agent through an exchanger for heating the hydrocarbon carrier prior to entering a stripper. | 2014-11-13 |
20140336434 | METHOD FOR REMOVAL OF ORGANIC AMINES FROM HYDROCARBON STREAMS - The present invention relates to a method for removal of an organic amine from a liquid hydrocarbon stream containing the amine, comprising: a) adding water to the hydrocarbon stream containing the amine, b) bubbling carbon dioxide through the hydrocarbon stream containing the amine, and c) separating a solid phase formed containing the amine from a liquid phase. | 2014-11-13 |
20140336435 | FLOW PROCESSING AND CHARACTERIZATION OF METAL-ORGANIC FRAMEWORK (MOF) MEMBRANES IN HOLLOW FIBER AND TUBULAR MODULES - A reactor cell for measuring gas and liquid permeation is disclosed. The reactor cell comprises a reactor module having a reactor chamber and a cover. A first hole extends into the reactor chamber from a first surface, a second hole opposing the first hole extends into the reactor chamber from a second surface, a third hole extends into the reactor chamber from a third surface and a fourth hole opposing the third hole extends into the reactor chamber from a fourth surface. A hollow fiber is supported by and sealed into the first and second holes of the reactor module. The first and second ends of the hollow fiber are sealed with a sealing solution. Methods for making and using the reactor cell are also disclosed. As made and used, the reactor cell further comprises a molecular sieving membrane grown on an inner bore surface of the hollow fiber. | 2014-11-13 |
20140336436 | Treatment of Aromatic Hydrocarbon Stream - The invention is directed to a process of contacting at least one zeolite, selected from the MWW family of zeolites, with an aromatic hydrocarbon stream in a system comprising at least one reactor containing the at least one zeolite, wherein the conditions in the reactor are adjusted in response to at least one measurement of the system so as to preferentially increase oxygenate removal or to preferentially increase olefin removal. | 2014-11-13 |
20140336437 | CEMENT CURING FORMULATION AND METHOD FOR HIGH-LEVEL RADIOACTIVE BORON WASTE RESINS FROM NUCLEAR REACTOR - A cement curing formulation and curing method for high-level radioactive boron waste resins from a nuclear reactor. The curing formulation comprises the following raw materials: cement, lime, water, curing aids and additives. The curing method comprises: (1) weighing the raw materials and the high-level radioactive boron waste resins, and adding lime into a curing container; (2) then adding the high-level radioactive boron waste resins; (3) feeding other raw materials under stirring; (4) adding the cement and supplementing water depending on the moisture state of the cement, and stirring until uniform; and (5) standing and maintaining after stirring until uniform. The curing formulation has the features of a high curing containment rate, high strength of the cured body, better water resistance, better freeze-thaw resistance, and low radioactive leakage. | 2014-11-13 |
20140336438 | BEAM SEGMENT-LEVEL DOSE COMPUTATION AND TEMPORAL MOTION TRACKING FOR ADAPTIVE TREATMENT PLANNING - A treatment planning system for generating patient-specific treatment. The system including one or more processors programmed to receive a radiation treatment plan (RTP) for irradiating a target over the course of one or more treatment fractions, said RTP including a planned dose distribution to be delivered to the target, receive motion data for at least one of the treatment fractions of the RTP, receive temporal delivery metric data for at least one of the treatment fractions of the RTP, calculate a motion-compensated dose distribution for the target using the motion data and the temporal delivery metric data to adjust the planned dose distribution based on the received motion data and temporal delivery metric data, and compare the motion-compensated dose distribution to the planned dose distribution. | 2014-11-13 |
20140336439 | PORTABLE PHANTOM DEVICE - A portable phantom device according to the present invention is a phantom device which is detachably installed in a bird cage that is coupled to an irradiator, and includes a body provided with an accommodation space having a cylindrical shape and a top of which is open so as to accommodate water, a horizontality adjustment maintaining portion which is detachably coupled to a side wall of the body; and a sensor holding portion which is installed on the side wall of the body so as not to interfere with the horizontality adjustment maintaining portion, so that a sensor for measuring the amount of radiation that is incident on the accommodation space may be inserted from the outside of the body and accommodated in the body (Representative drawing: FIG. | 2014-11-13 |
20140336440 | INHIBITORS OF RHO ASSOCIATED PROTEIN KINASES (ROCK) AND METHODS OF USE - Compounds and compositions having activity as inhibitors of Rho-associated proteinkinases (ROCKs), and methods of making and using the subject compounds are disclosed. | 2014-11-13 |
20140336441 | ENDORECTAL BALLOON WITH GAS RELEASE LUMEN - A rectal balloon apparatus comprises a shaft having a fluid passageway extending therethrough. A rectal gas relieving lumen may be positioned with a central shaft for removal of rectal gas. The gas releasing lumen can also or in the alternative be provided along an outer surface of the balloon. A motion detecting sensor and a radiation detecting sensor may be positioned with the balloon, the shaft, and/or the rectal gas release lumen. | 2014-11-13 |
20140336442 | HADRON TREATMENT PLANNING WITH ADEQUATE BIOLOGICAL WEIGHTING - Treatment planning methods are provided that determine the variability of relative biological effectiveness (RBE) along a beam line and calculate, among other things, what intensity of hadron beam such as a proton or a carbon ion beam should be applied to achieve a desired biological dose at treatment site of a patient afflicted with a medical condition. Typically, three or four RBE values at three or four corresponding spacially-dispersed intervals along the beam line are calculated. In one embodiment, two RBE values for the spread-out Bragg peak (SOBP) region of the treatment site; one for the proximal section and one for the declining distal section is calculated. A third and different RBE value may be determined for the distal edge region of the SOBP. A fourth value may also be calculated for a pre-SOBP region. | 2014-11-13 |
20140336443 | METHOD OF REPAIRING AGE AND DISEASE IMMUNE DYSFUNCTION AND CELLULAR SENESCENCE WITH LYMPHOID STEM CELLS AND THEN RE-APPLYING THOSE FOR THERAPEUTIC USE - This invention relates to methods for treatment of diseases of ageing including immunosenescence, immune dysfunction, inflammation and impairment of early lymphoid lineage differentiation. The invention more specifically relates to the use of granulocyte colony stimulating factors to assist in stem cell mobilization, optionally in combination with the application of a method of delivering precise magnetic field patterns which agree with the body's own natural magnetic field patterns, and further in combination with re-infusion of previously collected autologous cells and/or plasma, optionally including allogeneic (healthy donor) cells and blood plasma. | 2014-11-13 |
20140336444 | System and Method for Heart Pump Interrogation and Inspection - The present invention relates to systems and methods for in situ inspection, interrogation, and maintenance of heart pump function in subjects with an implanted heart pump. In certain embodiments, the system comprises a catheter assembly deliverable to the inflow port and outflow port of the implanted heart pump. The system comprises additional components used to examine pump function and prevent malfunction. In certain embodiments, the invention allows for temporary, mid-term, or permanent exclusion of the implanted heart pump from cardiac function without surgically removing the pump. | 2014-11-13 |
20140336445 | TRANSSEPTAL CANNULA, TIP, DELIVERY SYSTEM, AND METHOD - A cannula assembly, further comprising a cannula body for directing blood from the heart of a patient, having distal and proximal ends and a lumen therebetween. A tip coupled to the distal end of the body, the tip having an opening. A pump for drawing blood into the cannula assembly and dispensing the blood from the cannula assembly and into the patient circulatory system. The lumen of the cannula body further comprises a first inner diameter at the proximal end and a second inner diameter at the distal end, the first inner diameter being larger than the second inner diameter. A tapered portion defined as a decrease in inner diameter from the first inner diameter to the second inner diameter between the proximal and distal ends, the tapered portion configured to prevent cavitation of the blood within the cannula. | 2014-11-13 |
20140336446 | CAVOPULMONARY VISCOUS IMPELLER ASSIST DEVICE AND METHOD - A bearingless and sealless rotary blood pump is disclosed which provides multidirectional flow intended to provide low-pressure, high-volume right-sided partial assist circulatory support in a univentricular Fontan circulation on a permanent basis. The pump includes a housing and an impeller suspended in the center of the housing. The housing incorporates flow optimization features between inlet and outlet ends, as well as with the impeller surface. Large fluid gaps maintained between impeller and housing eliminate any potential for blood flow obstruction. The impeller contains some motor components. It includes a central stator and surrounding rotor. The motor includes a brushless DC outrunner electrical motor design. An electromagnetic stator core is surrounded by a circumferential passive magnetic ring. The rotor is further levitated about the stator spindle by a plurality of axially and radially located passive magnetic and hydrodynamic journal bearings on both ends of the spindle. The rotor is bearingless and sealless. During impeller rotation, blood entering the space between the rotor and stator is induced to flow by centrifugal pumping action and the fluid film separates the stator hydrodynamic bearings from the rotor so that there is no direct mechanical contact between the rotor and stator. | 2014-11-13 |
20140336447 | Medical Device Coupling Arrangement - Embodiments presented herein are generally directed to a coupling arrangement for securing an external component to a recipient of an implantable medical device. The coupling arrangement is configured to magnetically couple the external component to a recipient so as to minimize damage to tissue of the recipient adjacent to the coupling arrangement. | 2014-11-13 |
20140336448 | Method and System for Use of Hearing Prosthesis for Linguistic Evaluation - A method and system to help determine the extent to which a hearing prosthesis recipient is exposed to speech. The hearing prosthesis will log data regarding audio input, optimally in correspondence with times when the hearing prosthesis is in a stimulation-on mode in which the hearing prosthesis is set to stimulate a physiological system of the recipient in accordance with received audio input, so as to facilitate identification of speech to which the recipient is exposed. Further, as the hearing prosthesis itself receives the audio input, the hearing prosthesis may analyze the audio input to determine one or more linguistic characteristics of the audio input, such as a quantity of speech by the recipient and/or by others, and the hearing prosthesis may output data representing the determined one or more linguistic characteristics. Advantageously, the data may then be used to help facilitate rehabilitation of the recipient. | 2014-11-13 |
20140336449 | SYSTEMS AND METHODS FOR DELIVERING BONE CONDUCTION STIMULI TO AND FOR MEASURING GRAVITATION RECEPTOR FUNCTIONS OF THE INNER EAR - Disclosed herein are apparatus and methods for delivering bone conduction stimuli for measuring the gravitation receptor functions of the inner ear. In some embodiments, an apparatus may include (i) an impactor operatively linked to a guide disposed within a housing and (ii) an electrically driven actuator enclosed within the housing. The electrically driven actuator may be configured to cause the impactor to (i) travel to a striking point to deliver a mechanical bone conduction stimulus for transmission to a skull bone and (ii) controllably decelerate prior to the instance of stimuli delivery. | 2014-11-13 |
20140336450 | SYSTEMS AND METHODS EMPLOYING A PUSH TUBE FOR DELIVERING A URETHRAL SLING - In a general aspect, a method of treating urinary incontinence can include slidably interfitting a first push tube into a first dilator tube disposed at an end of a sling assembly and slidably interfitting the first push tube onto an end of a shaft of a delivery device. The method can also include inserting the shaft transvaginally through a vaginal wall and removing the shaft to implant a portion of the sling assembly in periurethral tissue. The method can also include slidably interfitting a second push tube into a second dilator tube disposed at a second end of the sling assembly and slidably interfitting the second push tube onto the end of the shaft. The method can still further include inserting the shaft transvaginally through the vaginal wall and removing the shaft from the patient to implant a second portion of the sling assembly in periurethral tissue. | 2014-11-13 |
20140336451 | SYSTEMS, DEVICES AND METHODS FOR MINIMALLY INVASIVE PELVIC SURGERY - The invention, in various embodiments, provides systems, devices, and methods for treating urinary incontinence. | 2014-11-13 |
20140336453 | PRESSURE SENSOR, ENDOSCOPE AND ENDOSCOPE DEVICE - There are provided a pressure sensor which can avoid an endoscope from causing intestinal perforation, an endoscope including the pressure sensor, and an endoscope device including the endoscope. There is provided a pressure sensor including a support unit and a pressure sensitive unit disposed on the ridge line of the front end of the support unit and configured to output a signal corresponding to an applied pressure. The pressure sensitive unit includes a first electrode disposed in a ring shape and multiple second electrodes opposed to the first electrode. The second electrodes are spaced in the circumferential direction of the first electrode. | 2014-11-13 |
20140336454 | APPARATUS AND SYSTEM FOR MANAGEMENT OF INSPECTION INFORMATION - An examination information management apparatus includes: a data transmitting and receiving unit that transmits and receives data to and from a receiving device for receiving image data captured by a capsule endoscope; a storage unit that stores examination information and the image data acquired in an examination; an ID maintaining unit that maintains an identification ID for identifying the storage unit; a determination unit that determines, when the identification ID is received from the receiving device via the data transmitting and receiving unit, whether or not the identification ID registered with the receiving device matches the identification ID maintained by the ID maintaining unit; and an examination information generating unit that newly generates examination information and causes the storage unit to store the image data received from the receiving device in association with the newly generated examination information, if the identification IDs are not determined by the determination unit to match each other. | 2014-11-13 |
20140336455 | TOROIDAL BALLOON-DRIVEN VEHICLE - A device fashioned in the shape of a toroid is rotated by a mechanism that propels itself in one or more directions based on internal rotation. In one specific example, the toroidal device is a toroidal balloon, where the tread of the toroidal balloon driven vehicle (TBDV) is self-contained and the entire outer surface is dynamic. Such a device is uniquely and ideally suitable for exploration of a tubular structure such as, but not limited to, the alimentary tract. | 2014-11-13 |
20140336456 | METHOD AND APPARATUS FOR STEERABLE, ROTATABLE, MICROENDOSCOPE WITH TOOL FOR CUTTING, COAGULATING, DESICCATING AND FULGURATING TISSUE - An exemplary embodiment providing one or more improvements includes a micro endoscope having steering, rotation and tool control function which can be utilized for insertion using a needle and catheter for performing arthroscopy and endoscopic procedures. | 2014-11-13 |
20140336457 | ENDOSCOPE - In the case of an endoscope | 2014-11-13 |
20140336458 | APPARATUS AND METHODS FOR HYBRID ENDOSCOPIC AND LAPAROSCOPIC SURGERY - Apparatus and methods are described allow the techniques of endoscopic and laparoscopic surgery to be combined into a minimally invasive hybrid surgical technique called NOTES-assisted laparoscopic surgery. Manual and robotic-controlled versions of a modular laparoscopic tool are described having a small diameter shaft that is delivered laparoscopically to a surgical site. Larger diameter working tips are delivered through a NOTES delivery tube inserted to the surgical site through a natural orifice and joined to the shaft of the modular laparoscopic tool. Larger diameter working tips improve the effectiveness of the modular laparoscopic tools and the number and size of laparoscopic ports used can also be reduced. | 2014-11-13 |
20140336459 | ENDOSCOPE ASSEMBLY WITH A POLARIZING FILTER - An endoscope includes an imaging device, a first polarizing filter disposed in front of the imaging device, a light source, and a second polarizing filter disposed in front of the light source. | 2014-11-13 |
20140336460 | STEREOSCOPIC ENDOSCOPE - Two side-by-side optical paths transmit stereoscopic right side and left side images onto the surface of a single image sensing chip. The single image sensing chip may be placed at various orientations with respect to the lens trains in the optical paths. In some embodiments a single prism is used to turn the light for both the right side and left side images onto the single image sensing chip. In other embodiments one prism is used to turn the light for the right side image and another prism is used to turn the light for the left side image, and the reflective surfaces of the two prisms are substantially coplanar such that the right side and left side images are incident on the single image sensor chip. | 2014-11-13 |
20140336461 | SURGICAL STRUCTURED LIGHT SYSTEM - A Surgical Structured Light (SSL) system is disclosed that provides real-time, dynamic 3D visual information of the surgical environment, allowing registration of pre- and intra-operative imaging, online metric measurements of tissue, and improved navigation and safety within the surgical field. | 2014-11-13 |
20140336462 | INSERTION PORTION DETECTION DEVICE AND INSERTION PORTION DETECTION SYSTEM - An insertion portion detection device provided with a light source unit which emits measuring beam to an outer circumferential surface of a cylindrical shape of an insertion portion to be inserted into an insertion target and to be a detection target, an optical pattern detection unit which receives reflected light from the outer circumferential surface and which sequentially acquires image data in a predetermined range of the outer circumferential surface including given optical patterns so that at least some of the optical patterns correspond to the image data, and a displacement amount calculation unit which detects a corresponding optical pattern from the image data and calculates at least one of an insertion amount of the insertion portion and an amount of rotation around the central axis of the cylindrical shape. | 2014-11-13 |
20140336463 | Rhinotopic therapy for the treatment of chronic rhinosinusitis biofilm disruption, treatment of mucosal granulation and sinus polyps - The herein disclosed invention is directed to methods of treating difficult to treat refractory or recalcitrant rhinosinusitis involving the steps of (1) topical application of antimicrobials/antibiotics and corticosteroids, (2) endoscopic debridement and cleansing to remove debris and biofilm, (3) endoscopic instillation of antimicrobials/antibiotics plus corticosteroids to the sinuses, and (4) hydrotherapy to disrupt/inhibit bacterial/fungal biofilm attachment to the sinus mucosa. Also disclosed is a kit of components for carrying out the treatment of this invention. | 2014-11-13 |
20140336464 | EXPANSION DEVICES AND METHODS OF USE THEREOF - Devices, systems, and methods for facilitating access to and visualization of the pancreaticobiliary system are disclosed. In particular, the present disclosure relates to devices used to expand and/or maintain the papilla opening to facilitate access therethrough, e.g., to visualize, examine, diagnose, and/or treat the bile duct and pancreatic ducts. The devices may include an elongate body, an expansion element having a compressed configuration and an expanded configuration, and an outer sheath. | 2014-11-13 |
20140336465 | METHOD AND APPARATUS FOR FIBERSCOPE EMPLOYING SINGLE FIBER BUNDLE FOR CO-PROPAGATION OF IMAGE AND ILLUMINATION - An exemplary embodiment providing one or more improvements includes an endoscope which utilizes a single coherent fiber bundle for simultaneously carrying imaging and illumination light. | 2014-11-13 |
20140336466 | GUIDING DEVICE FOR USE WITH LARYNGOSCOPE - A guiding device for use with a laryngoscope for assisting in the insertion of an endotracheal tube into a patient, the device comprising a guiding means for guiding an endotracheal tube through the patient's upper airways, and an attachment means to attach the guiding means to the blade of the laryngoscope. A laryngoscope comprising the guiding device is also disclosed. | 2014-11-13 |
20140336467 | OTOSCOPE - The otoscope comprises a head portion ( | 2014-11-13 |
20140336468 | METHOD OF RETRACTING BODY TISSUE DURING SURGERY - A retractor for use in spinal surgery comprises a frame including a ring member defining a generally central interior space. A plurality of blades is releasably supported respectively to slidable arms each supported on the ring member for individual translational movement relative to the ring member. The blades define an initial substantially enclosed opening that is expandable for use in a surgical procedure. A clutch mechanism supported on the ring member is associated with each arm to individually selectively engage each such arm with a rotatable main gear such that upon rotation of the main gear by a single actuator any one, all or any desired combination of arms may be translated relative to the ring member to move the blades and expand the opening in one or more selected desired directions. | 2014-11-13 |
20140336469 | CONTAGION PREVENTION SYSTEMS - A device for preventing the spread of bio-matter contagions when used in conjunction with a tongue depressor. The device includes a shield for intercepting the bio-matter contagions. The shield adjustably and removably secures along the tongue depressor. The device also includes a grip manipulator that extends from the shield. The grip manipulator adjustably engages the tongue depressor. The device also includes a window that provides viewing access through the shield. | 2014-11-13 |
20140336470 | REMOTE TRACTION AND GUIDANCE SYSTEM FOR MINI-INVASIVE SURGERY - A guide and remote traction system for mini-invasive surgery in a body cavity that is easily positioned and hooked and causes lower injury, comprising: | 2014-11-13 |
20140336471 | KIT OF PARTS FOR USE IN RETRACTING BODY TISSUE - A retractor for use in spinal surgery comprises a frame including a ring member defining a generally central interior space. A plurality of blades is releasably supported respectively to slidable arms each supported on the ring member for individual translational movement relative to the ring member. The blades define an initial substantially enclosed opening that is expandable for use in a surgical procedure. A clutch mechanism supported on the ring member is associated with each arm to individually selectively engage each such arm with a rotatable main gear such that upon rotation of the main gear by a single actuator any one, all or any desired combination of arms may be translated relative to the ring member to move the blades and expand the opening in one or more selected desired directions. | 2014-11-13 |
20140336472 | Comfortable Medical Headlamp Assembly - A battery headlamp assembly that includes a light engine bezel, an adjustable linkage supporting the bezel and including an electrically conductive system terminating at the bezel. Also, a headband assembly supports the adjustable linkage and includes a longitudinal rigid-flex circuit assembly. This assembly has a strip of rigid-flex circuit having two longitudinally opposed ends and including battery contacts on the ends. Also, two networks of electrical components are each supported by and electrically connected together, and to one of the battery contacts, by the strip of rigid-flex circuit, which includes conductive traces connecting both the networks to the electrically conductive system and to each other, to power the bezel from the battery contacts and to permit communications between the networks. In addition, a further electrically conductive element, electrically connects at least one conductive trace of the rigid-flex circuit to the electrically conductive system of the adjustable linkage. | 2014-11-13 |
20140336473 | Method and Apparatus for Encouraging Physiological Change Through Physiological Control of Wearable Auditory and Visual Interruption Device - A biofeedback system and method enables biofeedback training to be accomplished during normal interaction by an individual with the individual's environment, for example while reading, playing video games, watching TV, participating in sports activities, or at work. Physiologic data is processed and used to generate one or more control signals based on the physiologic data. The control signals may be proportional to a result of the data processing, or based on comparison of the processing results with at least one fixed or adaptive threshold. The control signal is supplied to a wearable device through which the individual receives sensory information from the individual's environment, and serves to interrupt or modify the sensory information. The wearable device may be an eyeglass device including a dynamic lens display, with the control signal being supplied to the dynamic lens display to modulate visual information received through the eyeglass device by obscuring, distorting, or otherwise affecting the clarity of the visual information. Feedback may also be provided in the form of auditory or tactile feedback. | 2014-11-13 |
20140336474 | HYBRID COMMUNICATION SYSTEM FOR IMPLANTABLE DEVICES AND ULTRA-LOW POWER SENSORS - Aspects of the present disclosure are directed toward apparatuses, systems, and methods that include a base unit and a communication circuit that communicate, while implanted in a patient, signals between the patient and at least one device located external to the patient. The base unit also includes a transducer that communicates ultrasound (US) signals between the base unit and the at least one device located external to the patient, and harvests energy carried by the US signals. | 2014-11-13 |
20140336475 | Methods and Means for Clinical Investigations - Described are methods for testing at least one effect of a pharmaceutical substance in a subject, which include administering a pharmaceutical substance to the subject, measuring with at least one sensor contained within a mobile sensor system, at the subject or in close proximity to the subject, at least one parameter value indicative of a the subject's body function, transmitting at least one sensor system signal associated with the at least one parameter value to a receiver contained within a mobile base unit, the receiver being provided with a means for wireless transmission, and wirelessly transmitting a mobile base unit signal associated with the at least one sensor system signal from the receiver to a back-end system, wherein at least the back-end system correlates the at least one parameter value with and/or displays a representation of the at least one effect of the pharmaceutical substance. | 2014-11-13 |
20140336476 | MICROCHIP SENSOR FOR CONTINUOUS MONITORING OF REGIONAL BLOOD FLOW - A sensor is provided available for continuous monitoring of regional blood flow in a tissue, including cerebral tissue. Methods of monitoring regional blood flow using the sensor as well as systems and computer readable medium therefor are also provided. | 2014-11-13 |
20140336477 | FAR-FIELD AND NEAR-FIELD ULTRASOUND IMAGING DEVICE - Devices, systems, and methods for ultrasonically acquiring far-field and near-field images within a body are disclosed. An ultrasound imaging device adapted for insertion within a body includes a first ultrasonic sensor configured to transmit ultrasonic waves at a first frequency for acquiring far-field images within the body, and a second ultrasonic sensor configured to transmit ultrasonic waves at a higher frequency than the first frequency for acquiring near-field images within the body. The ultrasound imaging device can be connected to a control device and user interface for visualizing far-field and near-field images acquired by the ultrasonic sensors. | 2014-11-13 |
20140336478 | OPTICAL SENSOR DEVICE AND IMAGE PROCESSING UNIT FOR MEASURING CHEMICAL CONCENTRATIONS, CHEMICAL SATURATIONS AND BIOPHYSICAL PARAMETERS - Optical sensor devices, image processing devices, methods and computer readable code computer-readable storage media for detecting biophysical parameters, chemical concentrations, chemical saturations, vital signs and physiological information such as a malignant condition are provided. In some embodiments, the optical sensor includes an array of photodetectors, where each photodetector is configured to detect a spectrum of light. In some embodiments, the image processing device receives a live still or video electronic image, or alternatively, the electronic image is provided from an electronic storage media. Exemplary physiological parameters include but are not limited to a pulse rate, a biophysical or physiological property of skin, a cardiovascular property, a property related to an organ such as the liver or the kidneys, and a temperature fluctuation. In some embodiments, the physiological parameter is indicative of a malady including but not limited to an autoimmune disease, a cancer, a nutritional deficiency, a malgiantn condition of bone marrow, a present of an infectious microbe such as a fungus, a present of hepatitis, and a cardiovascular disorder a pulmonary disorder. Exemplary chemical concentrations include but are not limited to a chemical saturation, a pH level, a pH level in blood vessels such as capillarys or in skin, a glucose level such as a blood glucose level, a urea nitrogen level such as a blood urea nitrogen level, a CO2 level such as a blood CO2 level or a CO2 saturation level, and an oxygen level such as a blood oxygen level or a blood oxygen saturation level. In some embodiments, the biophysical parameter, physiological parameter or chemical concentration is obtained from reflecting light from tissue from a mammalian subject. Alternatively one or more of these parameters are detected from a food item such as food tissue, a consumable beverage such as an alcoholic beverage, a dairy product, wine, a baked good, a fruit and a vegetable. Exemplary parameters related to food items include but are not limited to a parameter indicative of cooking or spoilage, a pH, a concentration of an antioxidant, and a concentration of an anti-inflammatory agent. | 2014-11-13 |
20140336479 | DETECTION METHOD OF LIFE ACTIVITY, MEASURING DEVICE OF LIFE ACTIVITY, TRANSMISSION METHOD OF LIFE ACTIVITY DETECTION SIGNAL, OR SERVICE BASED ON LIFE ACTIVITY INFORMATION - According to a measuring method or a control method of life activity, a life object is illuminated with an electromagnetic wave including a wavelength in a designated waveband, and a characteristic in a local area of the life object is detected, or a life activity thereof is controlled. The “designated waveband” is defined based on phenomena used for detecting or controlling an activity state of the life object or a change of the state. This “local area” is an area constituted by one or more cells. | 2014-11-13 |
20140336480 | CATALYSTS FOR BODY FLUID SAMPLE EXTRACTION - An arrangement for producing a sample of body fluid from a wound opening created in a skin surface at a sampling site includes at least one skin-penetration member having a first end configured to pierce the surface of the skin, and a inner lumen in communication with the first end; at least one actuator operatively associated with the at least one skin-penetration member; and at least one catalyst device configured to cause perfusion of body fluid at the sampling site; wherein the at least one actuator is configured to locate the at least one skin-penetration member so as to obstruct the wound opening while transporting body fluid through the inner lumen. Associated methods are also described. | 2014-11-13 |
20140336481 | MULTISPOT MONITORING FOR USE IN OPTICAL COHERENCE TOMOGRAPHY - Optical coherence tomography (herein “OCT”) based analyte monitoring systems are disclosed. In one aspect, techniques are disclosed that can identify fluid flow in vivo (e.g., blood flow), which can act as a metric for gauging the extent of blood perfusion in tissue. For instance, if OCT is to be used to estimate the level of an analyte (e.g., glucose) in tissue, a measure of the extent of blood flow can potentially indicate the presence of an analyte correlating region, which would be suitable for analyte level estimation with OCT. Another aspect is related to systems and methods for scanning multiple regions. An optical beam is moved across the surface of the tissue in two distinct manners. The first can be a coarse scan, moving the beam to provide distinct scanning positions on the skin. The second can be a fine scan where the beam is applied for more detailed analysis. | 2014-11-13 |
20140336482 | LASER DEVICE AND PHOTOACOUSTIC MEASUREMENT DEVICE - Disclosed is a laser device which can emit light having first and second wavelengths, having the advantage of increasing laser efficiency without causing an increase in cost. A flash lamp irradiates excitation light onto a laser rod. An optical resonator includes a pair of mirrors facing each other with the laser rod interposed therebetween. A wavelength switching unit includes a long path filter which transmits light having a wavelength equal to or greater than a first wavelength. The wavelength switching unit inserts the long path filter on the optical path of the optical resonator when the wavelength of laser light to be emitted is the first wavelength. | 2014-11-13 |
20140336483 | Method and Pulse Oximeter Apparatus Using Chemical Heating - Method and apparatus for providing reliable blood oxygen (Sa02) and heart rate measurements includes a chemical energy heating source in conjunction with a harness that is adapted to secure the chemical energy heating source and a pulse oximeter probe proximate to a region of the body which is to be warmed prior to measurement. Preferably, the chemical energy heating source is in the form a mixture including a metal powder, which releases heat at a predetermined rate via oxidation of the metal powder when exposed to the atmosphere. The apparatus may be designed to be reusable or disposable and can be used in a transmission or reflectance mode, or both. | 2014-11-13 |
20140336484 | METHODS AND SYSTEMS FOR ENDOBRONCHIAL DIAGNOSTICS - Methods and systems for targeting, accessing and diagnosing diseased lung compartments are disclosed. The method comprises introducing a diagnostic catheter with an occluding member at its distal end into a lung segment via an assisted ventilation device; inflating the occluding member to isolate the lung segment; and performing a diagnostic procedure with the catheter while the patient is ventilated. The proximal end of the diagnostic catheter is configured to be attached to a console. The method may also comprise introducing the diagnostic catheter into the lung segment; inflating the occluding member to isolate the lung segment; and monitoring blood oxygen saturation. The method may further comprise introducing the diagnostic catheter into the lung segment; determining tidal flow volume in the lung segment; determining total lung capacity of the patient; and determining a flow rank value based on the tidal flow volume of the lung segment and the total lung capacity. | 2014-11-13 |
20140336485 | DESIGN AND FABRICATION OF IMPLANTABLE FULLY INTEGRATED ELECTROCHEMICAL SENSORS - A fully integrated small size implantable sensing device is described, which can include a sensor and an electronic circuit to interface with the sensor and communicate with an external device. Various fabrication methods for the sensing device are described, including provision of wells, created using same fabrication technology as the electronic circuit, to contain electrodes of the sensor and corresponding functionalization chemicals. Such implantable sensing device can be used for a variety of electrochemical measuring applications within a living body as well as actuation by injecting a current into the living body. | 2014-11-13 |