45th week of 2015 patent applcation highlights part 35 |
Patent application number | Title | Published |
20150316490 | REMOVING PROCESS-VARIATION-RELATED INACCURACIES FROM SCATTEROMETRY MEASUREMENTS - Metrology methods and respective software and module are provided, which identify and remove measurement inaccuracy which results from process variation leading to target asymmetries. The methods comprise identifying an inaccuracy contribution of process variation source(s) to a measured scatterometry signal (e.g., overlay) by measuring the signal across a range of measurement parameter(s) (e.g., wavelength, angle) and targets, and extracting a measurement variability over the range which is indicative of the inaccuracy contribution. The method may further assume certain functional dependencies of the resulting inaccuracy on the target asymmetry, estimate relative donations of different process variation sources and apply external calibration to further enhance the measurement accuracy. | 2015-11-05 |
20150316491 | SIMULATED BIOLOGICAL MATERIAL FOR PHOTOACOUSTIC DIAGNOSTIC APPARATUS AND METHOD FOR MANUFACTURING THE SAME - A simulated biological material for photoacoustic diagnostic apparatus contains a polyol or a cured material produced from a polyol and a polyisocyanate, and titanium oxide fine particles in the polyol or the cured material. The titanium oxide fine particles are surface-treated with a polysiloxane having a Si—H partial structure. | 2015-11-05 |
20150316492 | Apparatus and Method of Detecting Foreign Material on Upper Surface of Transparent Substrate Using Polarized Light - Provided are an apparatus and a method of detecting a foreign material capable of detecting only a foreign material on a surface of a substrate except for a foreign material on a lower surface of the substrate in a manufacturing process of a transparent substrate passing light therethrough, such as a glass substrate used in a flat panel display (FPD) such as a liquid crystal display (LCD), an organic light emitting diode (OLED), a plasma display panel (PDP), a sapphire wafer used in some of semiconductors, or the like, and in a pattern forming process in a manufacturing process of the FPD and the semiconductor using the transparent substrate. | 2015-11-05 |
20150316493 | LABORATORY X-RAY MICRO-TOMOGRAPHY SYSTEM WITH CRYSTALLOGRAPHIC GRAIN ORIENTATION MAPPING CAPABILITIES - A method and system for three dimensional crystallographic grain orientation mapping illuminates a polycrystalline sample with a broadband x-ray beam derived from a laboratory x-ray source, detects, on one or more x-ray detectors, diffracted beams from the sample, and processes data from said diffracted beams with the sample in different rotation positions to generate three dimensional reconstructions of grain orientation, position, and/or 3-D volume. A specific, cone beam, geometry leverages the fact that for a point x-ray source with a divergent beam on reflection of an extended crystal grain diffracts x-rays such that they are focused in the diffraction plane direction. | 2015-11-05 |
20150316494 | X-RAY SHIELD GRATING AND X-RAY TALBOT INTERFEROMETER INCLUDING X-RAY SHIELD GRATING - An X-ray shield grating includes a substrate on which a plurality of recessed portions are arranged, and metal that is arranged in each of the recessed portions. The substrate includes a bent region that is bent in an arrangement direction in which the plurality of recessed portions are arranged. A radius of curvature of the bent region is 200 millimeters or less. In the bent region, a maximum value of a width of a region sandwiched between two adjacent recessed portions of the plurality of recessed portions and a width of the substrate in an end portion of the bent region are less than or equal to three times a minimum value of the width of the region sandwiched between the two adjacent recessed portions. | 2015-11-05 |
20150316495 | METHOD FOR DETECTING PHASE CHANGE TEMPERATURES OF MOLTEN METAL - A detection device for molten metal is provided. The detection device includes a sample cup having a cavity configured to receive a sample of molten metal and a blob arranged in the cavity. The blob includes a carbide stabilizing element and a hydrogen releasing material including a hydroxide of an alkaline earth metal. The blob is provided for use in detecting phase change temperatures during solidification of a sample of molten cast iron. The blob is also resistant to moisture gain and moisture loss during transport and storage. A method of detecting phase change temperatures of the molten iron or molten cast iron sample using the blob and a method of manufacturing the blob are also provided. | 2015-11-05 |
20150316496 | DEVICE AND METHOD FOR ANALYZING DEFECTS BY USING HEAT DISTRIBUTION MEASUREMENT - The present invention provides a method for analyzing defects by using heat distribution measurement, comprising: a sample loading unit for loading a sample to check whether or not there is a defect through heat distribution characteristics; a light source for radiating visible light onto the sample; a power supply unit for generating a driving signal in order to periodically heat the sample; a detection unit for detecting reflected light from the surface of the sample; and a signal generator for synchronizing the detection unit with the driving signal of the power supply unit. | 2015-11-05 |
20150316497 | WIRELESS SUBSOIL TENSION SENSOR - A wireless subsoil tension meter is disclosed, including an upper housing part, a middle housing part, a lower housing part, and a sensor module. The upper, middle and lower housing parts are assembled to form a sealed space to house a sensor module and liquid. The upper housing part has a tubular body shape. The middle housing part has a funnel body shape, with a larger top and the smaller bottom, the top end of the middle housing part is slightly smaller than the inside the bottom end of the outer tube of the upper housing part for easy assembly and tight fit. The lower housing part is has an elongated dome shape. When assembled, the sensor module is housed inside the assembly, which can further be applied to an extendable wireless soil measurement apparatus. | 2015-11-05 |
20150316498 | Integrated CMOS Porous Sensor - A single chip wireless sensor comprises a microcontroller connected by a transmit/receive interface to a wireless antenna. The microcontroller is also connected to an 8 kB RAM, a USB interface, an RS232 interface, 64 kB flash memory, and a 32 kHz crystal. The device senses humidity and temperature, and a humidity sensor is connected by an 18 bit ΣΔ A-to-D converter to the microcontroller and a temperature sensor is connected by a 12 bit SAR A-to-D converter to the microcontroller. The device is an integrated chip manufactured in a single process in which both the electronics and sensor components are manufactured using standard CMOS processing techniques, applied to achieve both electronic and sensing components in an integrated process. | 2015-11-05 |
20150316499 | PHYSIOLOGICAL CHARACTERISTIC SENSORS AND METHODS FOR FORMING SUCH SENSORS - A physiological characteristic sensor, a method for forming a physiological characteristic sensor, and a method for forming a platinum deposit having a rough surface are presented here. The method for forming a physiological characteristic sensor includes immersing a sensor electrode in a platinum electrolytic bath. Further, the method includes performing an electrodeposition process by sequentially applying a pulsed signal to the sensor electrode and applying a non-pulsed continuous signal to the sensor electrode to form a platinum deposit on the sensor electrode. | 2015-11-05 |
20150316500 | DEVICE INCLUDING BIOSENSOR AND HOLDER - A device utilising biosensors to enable rapid electrochemical sensing of one or more analytes in a container. The device comprises a holder which incorporates at least one reference electrode and at least one sensing electrode. The sensing electrode comprising an electrically conductive substrate which is coated in a first layer of a suitable electron acceptor and subsequently with a second layer incorporating a biorecognition molecule adsorbed or within a suitable electropolymer matrix or carrier. | 2015-11-05 |
20150316501 | GATED VOLTAMMETRY METHODS - A sensor system, device, and methods for determining the concentration of an analyte in a sample is described. Gated voltammetric pulse sequences including multiple duty cycles of sequential excitations and relaxations may provide a shorter analysis time and/or improve the accuracy and/or precision of the analysis. The disclosed pulse sequences may reduce analysis errors arising from the hematocrit effect, variance in cap-gap volumes, non-steady-state conditions, mediator background, a single set of calibration constants, under-fill, and changes in the active ionizing agent content of the sensor strip. | 2015-11-05 |
20150316502 | DEBYE LENGTH MODULATION - Systems and methods for detection of biological agents are generally described. | 2015-11-05 |
20150316503 | Differential Pair Sensing Circuit Structures - A differential pair sensing circuit ( | 2015-11-05 |
20150316504 | PRESENTING STRETCHED STRANDS OF SINGLE STRAND DNA FOR SEQUENCING DOUBLE STRAND DNA - A mechanism is provided for presenting single strands of a double strand molecule to a membrane. The double strand molecule is driven to a first side of the membrane by an electric field. The membrane has a first and second nanopore spaced apart by a nanopore separation distance. The first strand of the double strand molecule is captured in the first nanopore when driven to the first side of the membrane. The second strand is captured in the second nanopore by having the nanopore separation distance between the first nanopore and the second nanopore corresponding to a strand separation distance between the first and second strands, and/or by having captured the first strand to limit diffusion of the second strand. The first and second strands respectively in the first and second nanopores are individually stretched, by the first and second strands recombining on the second side of the membrane. | 2015-11-05 |
20150316505 | Methods And Devices For Sequencing Nucleic Acids In Smaller Batches - The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. A plurality of smaller flow cells is employed, each with a relatively small area to be imaged, in order to provide greater flexibility and efficiency. | 2015-11-05 |
20150316506 | Correction of Time of Flight MS ADC Data on Push by Push Basis - A method of mass spectrometry is disclosed comprising pulsing ions into a time of flight region and detecting the ions using an ion detector. The signal output from the ion detector is digitised to produce a digitised signal. The peak area A | 2015-11-05 |
20150316507 | METHODS FOR ANALYSIS OF ISOMERIC LIPIDS - A method for analyzing a sample that contains a plurality of lipid isomers is described that involves forming one or more lipid metal ion adducts and transporting the one or more lipid metal ion adducts through a Mix of POPC+OPPC differential mobility spectrometer to cause separation of the one or more lipid metal ion adducts from each other. The lipid isomers can be chosen, for example, from fatty acids, glycerolipids, glycerophospholipids, sphingolipids, saccharolipids, polyketides, sterol lipids, and prenol lipids. Particular examples include phosphatidylcholine regioisomers such as 1-palmatoyl-2-oleoyl-sn-phosphatidylcholine (POPC) and 1-oleoyl-2-palmatoyl-sn-phosphatidylcholine and triacylglycerols containg palmetic and oleic acid groups. The metal chosen can include a cationization reagent that contains sodium, potassium, silver or lithium. | 2015-11-05 |
20150316508 | APPARATUS AND METHOD FOR DETECTING INNER DEFECTS OF STEEL PLATE - An apparatus for detecting inner defects of a steel plate comprises an all-defect detection unit for detecting all defects including surface defects present on the surface of the steel plate and inner defects present inside the steel plate by intensity of leakage flux, measured by generating magnetic flux in a strike direction of the steel plate; a surface defect detection unit for detecting surface defects by intensity of leakage flux, measured by generating magnetic flux in the thickness direction of the steel plate, for a predetermined detection region including all the defects detected by the all-defect detection unit; and a data processing unit for detecting only inner defects present in a detection region by excluding the detected surface defects from all the defects detected by the all-defect detection unit, for the detection region, thereby detecting only the inner defects of the steel plate. | 2015-11-05 |
20150316509 | METHOD FOR MEASURING THICKNESS OF BOILER WATER TUBE - An inspection hole is formed on a side surface of a boiler water tube in a longitudinal direction, a base side of a guide pipe is connected to the inspection hole, and usually, a closing member is attached to the guide pipe. In a case where the thickness of the boiler water tube is measured, the closing member is released from the guide pipe, an ultrasonic probe is inserted into the boiler water tube from a tip side of the guide pipe, and the ultrasonic probe is moved in the boiler water tube. | 2015-11-05 |
20150316510 | PHOTOACOUSTIC MICROSCOPE - A photoacoustic microscope includes an objective lens that irradiates a specimen with excitation light, a light scanning unit that deflects the excitation light to scan the specimen, an acoustic lens that converts a wavefront of a photoacoustic wave generated by the specimen due to irradiation with the excitation light, a photoacoustic wave detection unit that detects the photoacoustic wave from the acoustic lens, a drive unit that displaces at least one of the acoustic lens and the photoacoustic wave detection unit, and a control unit that controls the drive unit, in synchronization with scanning of the excitation light by the light scanning unit, so that the photoacoustic wave is incident on the photoacoustic wave detection unit perpendicularly. | 2015-11-05 |
20150316511 | REAL-TIME DETECTION AND IMAGING OF TERAHERTZ PULSE RADIATION BY USING PHOTOACOUSTIC CONVERSION - Methods and devices for high speed detection of terahertz radiation are provided. A photoacoustic transducer receives a pulse of terahertz (THz) radiation. The transducer may comprise a solid, liquid, or semi-solid material. For example, the transducer may be a composite material having a polymer and radiation absorbing particles. The photoacoustic transducer produces an acoustic wave (e.g., an ultrasound wave) in response to receiving the pulse of THz radiation. An acoustic sensor receives the acoustic wave produced by the photoacoustic transducer and thus provides detection of the THz wave. | 2015-11-05 |
20150316512 | METHOD AND DEVICE FOR ACOUSTICALLY DETECTING A MALFUNCTION OF A MOTOR HAVING AN ACTIVE NOISE CONTROL - The present invention relates to a method for acoustically detecting at least one malfunction (DYS) of a motor, the motor generating a primary noise Po that is treated by an active noise control system emitting, at the noise reduction targets, an acoustic signal Pc produced by at least one actuator and connected by a transfer function H to a signal Y produced by said active noise control system, said malfunction (DYS) having an acoustic signature identifiable in the primary noise Po at the noise reduction targets, characterised in that it comprises the following steps: acquisition of said signal Y produced by the active control system; identification of the appearance, if any, of a malfunction by a monitoring means that uses the knowledge of Y and H and emits an alert message if warranted. | 2015-11-05 |
20150316513 | METHOD AND APPARATUS FOR SCANNING A TEST OBJECT - The present disclosure relates to a method and an apparatus for scanning a test object. A reference object is scanned to build a gain correction map including gain values for scanning points on a surface of the reference object. The test object is also scanned to obtain measurements for scanning points on a surface of the test object. Amplitudes of the measurements obtained for the scanning points on the surface of the test object are normalized using the gain values of the gain correction map. The apparatus has a probe mounted on a mechanical scanner, and a controller controlling the scanning and normalizing operations. The method and apparatus can be used to create an image of the test object for non-destructive testing. | 2015-11-05 |
20150316514 | SIGNAL PROCESSING DEVICE, ULTRASOUND DIAGNOSTIC APPARATUS, AND SIGNAL PROCESSING METHOD - A signal processing device which uses a first signal waveform of ultrasound reflected from an object in a first compressed state and a second signal waveform of ultrasound reflected from the object in a second compressed state and calculates an elasticity of the object affected by a change in a compressed state includes: a phase difference calculation unit which calculates a phase difference component in each time between the first signal waveform and the second signal waveform; a correlation calculation unit which calculates an elasticity pertaining to a difference in angular frequencies between the first signal waveform and the second signal waveform and an initial phase difference according to a correlation between the each time and the phase difference component in the each time; and an elasticity calculation unit which calculates the elasticity on the basis of the difference in angular frequencies. | 2015-11-05 |
20150316515 | MATERIALS FOR HYDROPHILIC INTERACTION CHROMATOGRAPHY AND PROCESSES FOR PREPARATION AND USE THEREOF FOR ANALYSIS OF GLYCOPROTEINS AND GLYCOPEPTIDES - The invention relates to poly-amide bonded hydrophilic interaction chromatography (HILIC) stationary phases and novel HILIC methods for use in the characterization of large biological molecules modified with polar groups, known to those skilled in the art as glycans. The invention particularly provides novel, poly-amide bonded materials designed for efficient separation of large biomolecules, e.g. materials having a large percentage of larger pores (i.e. wide pores). Furthermore, the invention advantageously provides novel HILIC methods that can be used in combination with the stationary phase materials described herein to effectively separate protein and peptide glycoforms by eliminating previously unsolved problems, such as on-column aggregation of protein samples, low sensitivity of chromatographic detection of the glycan moieties, and low resolution of peaks due to restricted pore diffusion and long intra/inter-particle diffusion distances. | 2015-11-05 |
20150316516 | MIXER BYPASS SAMPLE INJECTION FOR LIQUID CHROMATOGRAPHY - In a liquid chromatography system, a sample is injected into a column by flowing a solvent mixture from a mixer into the column along a solvent mixture flow path; and injecting a sample into the solvent mixture flow path downstream of the mixer. In another liquid chromatography system, a sample is injected into a column by loading an isolator fluid into a sample loop, loading a sample into the sample loop, and flowing the sample into the column as a plug in front of the isolator fluid. | 2015-11-05 |
20150316517 | DEVICE COMPRISING A FLUID CHANNEL PROVIDED WITH AT LEAST ONE MICRO OR NANOELECTRONIC SYSTEM AND METHOD FOR CARRYING OUT SUCH A DEVICE - Device including a substrate including at least one microelectronic and/or nanoelectronic structure (NEMS) having a sensitive portion and a fluid channel. The fluid channel includes two lateral walls, an upper wall connecting the two lateral walls, a lower wall formed by the substrate, and at least two openings in order to provide a circulation in the fluid channel, with the openings being defined between the two lateral walls, with the structure being located inside the fluid channel. Electrical connection lines extend between the structure and the outside of the fluid channel, with the connection lines being carried out on the substrate and passing under the lateral walls. The device also includes an intermediate layer having a planar face in contact with base faces of said lateral walls. The connection lines are at least partially covered by the intermediate layer at least immediately above base faces of the lateral walls. The lateral walls are made sealingly integral on the substrate by a sealing layer on the intermediate layer. | 2015-11-05 |
20150316518 | METHOD FOR QUANTITATION OF ACID SITES IN ACIDIC CATALYSTS USING SILANE AND BORANE COMPOUNDS - A method of quantifying an amount of Brønsted acid sites in an aluminum chloride-containing catalyst is described. The method involves adding a known amount of at least one silane or borane compound to the aluminum chloride-containing catalyst being analyzed. The Brønsted acid sites in the aluminum chloride-containing catalyst react with the silane or borane compound to form a silyl boryl compound, resulting in a catalyst phase and a hydrocarbon phase which contains the silyl or boryl compound. The amount of silyl or boryl compound in the hydrocarbon phase is measured. From the measured amount of silyl or boryl compound formed, the amount of Brønsted acid sites can be determined. | 2015-11-05 |
20150316519 | METHOD FOR QUANTITATION OF ACID SITES IN ACIDIC IONIC LIQUIDS USING SILANE AND BORANE COMPOUNDS - A method of quantifying an amount of Brønsted acid sites in an acidic ionic liquid is described. The method involves adding a known amount of at least one silane or borane compound to the acidic ionic liquid being analyzed. The Brønsted acid sites in the acidic ionic liquid react with the silane or borane compound to form a silyl or boryl compound, resulting in an ionic liquid phase and a hydrocarbon phase which contains the silyl or boryl compound. The amount of silyl or boryl compound in the hydrocarbon phase is measured. From the measured amount of silyl or boryl compound formed, the amount of Brønsted acid sites can be determined. | 2015-11-05 |
20150316520 | PERSONALIZED CAPNOGRAPHY - Control logic, device and method including same configured to receive a measured carbon dioxide (CO | 2015-11-05 |
20150316521 | Controlled Environment Shipping Containers - Systems and apparatus are provided for maintaining an ultra low oxygen concentration in a shipping container for the purpose of preventing spoilage of perishable food products. The system and apparatus may contain a composition of a mixture of gases including one or more of nitrogen, carbon dioxide, and another inert gas, wherein the mixture of gases positively pressurizes the shipping container with an ultra low oxygen concentration. The system and apparatus may use one or more sensors to monitor the composition of the mixture of gases, and may use one or more controllers to release the compressed gases into the interior of the container. The controller may release the compressed gases at a variable rate of release sufficient to maintain the ultra low oxygen concentration and to ensure consistent concentrations of the mixture of gases with the container. | 2015-11-05 |
20150316522 | METHODS AND DEVICES FOR DETECTION OF THE CONCENTRATION OF AT LEAST ONE GASEOUS TARGET SUBSTANCE AND USE OF A GAS MONITORING DEVICE - The invention concerns a method for detection of the concentration of at least one gaseous target substance ( | 2015-11-05 |
20150316523 | SYSTEMS AND METHODS FOR IDENTIFYING EXPLOSIVES - A method and a system for identifying an explosive in a sample are disclosed. The method comprises receiving an explosive fingerprint defined by a set of kinetic parameters, describing a plurality of interactions between the explosive and each of a respective plurality of functional moieties. The method further comprises using a data processor for accessing a database of explosive fingerprints, and searching the database for a database fingerprint matching the received fingerprint. The system comprises a plurality of sensing devices, each comprising semiconductor nanostructures (e.g. Si nanowires) having attached thereto a functional moiety selected to interact with a nitro-containing and/or peroxide-containing explosive sample. | 2015-11-05 |
20150316524 | System and Apparatus for a Laboratory Scale Reactor - The present disclosure may include a device for testing catalysts, and a method for controlling the flow rate and temperature parameters during the process. The device may separate mass flow control through heating elements from the mass flow through the sample, as well as separate banks for mixing oxidizing elements, carbon dioxide, and diluent gas as well as reducing agents, nitric oxide, and diluent gas. The device disclosed here may also use mass control units of a sufficiently high speed so as to allow the desired testing conditions. | 2015-11-05 |
20150316525 | A METHOD OF ANALYSING AN IRON MELT - A method of analysing an iron melt for producing compacted graphite iron includes receiving thermal data from cooling of a cast melt including a predetermined amount of carbon, magnesium, balance iron and unavoidable impurities, plotting the temperature of the cast melt against time such that a plotted time-temperature curve is generated, comparing the generated plotted curve to at least one reference curve, the reference curve representing a corresponding thermal analysis of another melt, the resulting nodularity of which is known, for the purpose of predicting the nodularity of the cast melt on basis of the difference between the curves. The comparison on which the nodularity is predicted is performed along each of the curves for a time interval t | 2015-11-05 |
20150316526 | INTELLIGENT PAD FOOT SOIL COMPACTION DEVICES AND METHODS OF USING SAME - Proper soil compaction is critical to providing structural support in any geo-construction project, particularly road construction. Described herein are devices, methods, and systems for intelligent soil compaction. In some embodiments, these disclosed systems, methods, and devices can provide up to 100% coverage with mechanistic measurements through machine integrated devices. These novel in-situ material characterization devices and methodologies enable continuous, mechanistic monitoring of soil compaction for use with a variety of geo-construction devices, including static pad foot soil compactors. In one embodiment, a strain gage instrumented pad is integrated into a pad foot soil compactor, and contact force is measured instrumented pad that is sensitive to soil compaction. In other embodiments, the disclosed device may allow for mechanistic measurements that may use a simplified geometry, and numerical and analytical modeling. In some embodiments, an inverse model, based on finite element modeling, may be used to extract constitutive parameters from plate strains. | 2015-11-05 |
20150316527 | AUTOMATED DRILLING FLUID ANALYZER - An automatic drilling fluid property analyzer including a housing having an inlet and an outlet; at least one valve disposed proximate the inlet and configured to open and close to provide a sample of fluid into the housing; an electronic control module configured to send a signal to the at least one valve; a probe assembly operatively coupled to the electronic control module, the probe assembly including an electrode probe having two electrodes and a probe gap therebetween; a viscometer sleeve disposed in the housing; a bob disposed in the sleeve, wherein an annulus is formed between the viscometer sleeve and the bob, and wherein at least one of the viscometer sleeve and the bob is configured to rotate, a motor operatively coupled to at least one of the viscometer sleeve and the bob; and a torque measuring device operatively coupled to the viscometer sleeve and the bob. | 2015-11-05 |
20150316528 | SINGLE-USE BIOREACTOR SENSOR ARCHITECTURE - A sensor assembly includes a first sensor and a second sensor. An enclosure is operably coupled to each of the first and second sensors and contains memory that stores compensation data for each of the first and second sensors. A connector is operably coupled to the first and second sensors. A bioreaction sensing assembly as well as a method of manufacturing the bioreaction sensing assembly is also provided. | 2015-11-05 |
20150316529 | SYSTEM AND METHOD FOR REAL-TIME ANALYSIS OF MOLECULAR SEQUENCES USING NANOCHANNELS - The present invention relates to a system for analyzing molecular sequences, which is capable of decoding unit molecules constituting various biopolymers on a real-time basis using nanochannels. A control electrode serves to control the unit molecules passing along the channel such that the velocity of movement, arrangement, and directivity of the unit molecules can be rendered uniform. Particularly, at least four probe electrodes are separately formed in the case of decoding ss-DNA base molecules. Each probe electrode is coated with four different types of DNA base molecules to maximize detection efficiency through the interaction with complementary base molecules moving along the inside of the channel. | 2015-11-05 |
20150316530 | USING A FIELD EFFECT DEVICE FOR IDENTIFYING TRANSLOCATING CHARGE-TAGGED MOLECULES IN A NANOPORE SEQUENCING DEVICE - A detector apparatus includes a field-effect transistor configured to undergo a change in amplitude of a source-to-drain current when at least a portion of a charge-tagged molecule translocates through the nanopore. In some implementations, the field-effect transistor is a carbon nanotube field effect transistor and the nanopore is located in a membrane. In other implementations, the field-effect transistor is a carbon nanotube field effect transistor and the nanopore is implemented in the form of a nano-channel in a semiconductor layer. | 2015-11-05 |
20150316531 | Automated Analyzer and Automated Analysis Method - Provided is technology for blood clotting reactions capable of analyzing a blood clotting reaction with a high degree of precision, by precisely detecting and removing noise, regardless of the location where the noise is generated in the light intensity data. This automated analyzer approximates, with an approximation curve, time series data for transmitted light intensity or scattered light intensity of light emitted onto a sample, and, in this process, removes abnormal data points that deviate from the approximation curve (see | 2015-11-05 |
20150316532 | AUTOMATIC ANALYZER - An automatic analyzer which realizes stable reagent heating and high dispensing accuracy includes a thermostat bath for controlling a reagent or a reaction solution in reaction cells arranged on a circumference of a reaction disk to have a constant temperature; a first reagent dispensing mechanism dispenses a reagent into the reaction cells; a photometer detects transmitted light or scattered light in the reaction cell; and a disposable reaction container for allowing the sample and the reagent to mix and react with each other. The analyzer also includes a second reagent dispensing mechanism with a reagent heating function which dispenses the reagent into the disposable reaction container; a coagulation time detection section; a reaction container temperature control block; a reagent dispensing syringe which is connected to the second reagent dispensing mechanism; and a fluid temperature control mechanism which controls the temperature of an internal fluid of the reagent dispensing syringe. | 2015-11-05 |
20150316533 | METHODS AND SYSTEMS FOR POINT-OF-CARE COAGULATION ASSAYS BY OPTICAL DETECTION - This invention relates to an optical system and method for performing turbidity assay, e.g. coagulation of blood or plasma, comprising a standard optical reference, a sample handling structure, a light source and an optical detection unit. The standard optical reference, such as a fluorophore-doped glass, provides constant optical signal under controlled optical conditions. The sample handling structure, such as a microfluidic system with reaction chamber, can be placed beneath or above the standard optical reference. During operation, the coagulating plasma/blood changes its optical absorbance and reflection properties, which results in changes in optical signal that reaches the optical reading unit. The variation of the optical signal, such as fluorescence signal indicates the kinetics of the turbidity varying process, such as plasma/blood coagulation process. This invention is used for performing turbidity assay with optical system, including photometry system, fluorescence system, Raman Spectroscopy system and so on. | 2015-11-05 |
20150316534 | Apparatus and Cartridge for Hemostasis Testing - A sample testing cartridge is usable to perform a variety of tests on a visco-elastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis. | 2015-11-05 |
20150316535 | CARDIAC STEM CELLS AND METHODS OF IDENTIFYING AND USING THE SAME - Methods of isolating cardiac cells, including cardiac cells capable of regenerating cardiac tissue are provided. Compositions comprising cardiac cells, including cardiac cells capable of regenerating cardiac tissue are also provided. Methods of using cardiac cells, cardiac progenitor cells, including cardiac cells capable of regenerating cardiac tissue, are provided. Methods of identifying the prognosis of patients treated for heart disease and/or methods of predicting the regeneration of cardiac cells in a subject are also provided. | 2015-11-05 |
20150316536 | METHODS FOR SCREENING - Methods and systems for discovering drug candidates are disclosed. Methods and systems can include generating libraries of potential drug candidates (e.g., libraries of peptides) that can be screened to identify sub-libraries of potential drug candidates (e.g., sub-libraries of peptides) having selected pharmacological properties. Methods of making and using peptide libraries are also provided. D-amino acid chlorotoxins and D-amino acid chlorotoxin variants are also provided. | 2015-11-05 |
20150316537 | METHOD OF IDENTIFYING OR EVALUATING SYNERGISTIC COMBINATIONS OF ACTIVES AND COMPOSITIONS CONTAINING THE SAME - A method of identifying or evaluating synergistic combinations of actives such as skin-care actives that improve the metabolism of a cell and provides an advantage over using the actives alone. The method includes contacting cells with test agents, alone and in combination, and determining a response of the cells to the test agent(s), wherein the response corresponds to a change in a metabolic indicator associated with glycolysis and a change in a metabolic indicator associated with oxidative phosphylation. | 2015-11-05 |
20150316538 | TREATMENT OF EGF-RECEPTOR DEPENDENT PATHOLOGIES - Disclosed are methods for treating a subject with an EGFR dependent pathology. The method comprises the step of administering to the subject an effective amount of an agent (“First Agent”) that decreases the biological activity of iRhom1 and an effective amount of an agent (“Second Agent”) that decreases the biological activity of iRhom2. Alternatively, the method comprises the step of administering to the subject an effective amount of an agent (“First Agent”) that modulates formation of a complex between iRhom 1 and TACE and an effective amount of an agent (“Second Agent”) that modulates formation of a complex between TACE and iRhom2. Also disclosed are assays for identifying such agents. | 2015-11-05 |
20150316539 | Micropillar Arrays for Assaying Myelination - Micropillar arrays for assaying differentiation of oligodendrocyte precursor cells into oligodendrocytes, ensheathment, and/or wrapping of the micropillars by the oligodendrocytes is provided. Also provided herein are methods of using the micropillar arrays for screening of candidate agents that promote differentiation of oligodendrocyte precursor cells into oligodendrocytes, ensheathment, and/or wrapping of the micropillars by the oligodendrocytes. A system comprising micropillar arrays and oligodendrocyte precursor cells are also provided. | 2015-11-05 |
20150316540 | REDUCING/OXIDIZING ACTIVITY OF MATERNAL URINE AS INDICATOR OF FETAL GENDER RELATED CHARACTERISTICS - The present invention provides a method for determining the gender of an unborn child by assaying the overall reducing/oxidizing or redox activity of the maternal urine or other body fluid. The method can be used to determine fetal gender at any time point during the entire pregnancy, the earliest being the first day of a missed menstruation. The body fluid may be processed before assaying. Processing may involve aging the body fluid, or purification of various fractions. The methods of the present invention also provide for a means for pre-conception baby gender planning by assaying the overall redox activity of a non-pregnant female's urine or other body fluid. The overall redox activity of a urine sample correlates with the gender specific compatibility of the ovum being released during a particular menstrual cycle. Therefore, assaying the overall redox activity of a non-pregnant female's urine will help a couple conceive a baby having a desired gender. | 2015-11-05 |
20150316541 | METHOD FOR IMMUNOLOGICALLY ASSAYING HEMOGLOBIN A1C IN SPECIMEN - Means that enables an immunoassay of hemoglobin A1c in a whole blood sample without pretreatment of the sample is disclosed. The immunoassay of hemoglobin A1c in a sample according to the present invention comprises bringing latex particles into contact with a non-pretreated whole blood sample in a hypotonic solution, and then bringing hemoglobin A1c adsorbed on the latex particles into contact with an anti-hemoglobin A1c antibody. The immunoassay is preferably carried out by an agglutination method. The hypotonic solution is, for example, a buffer containing a Good's buffer at a concentration of 0.02 to 0.2 mol/L, which Good's buffer has the maximum buffer capacity in the neutral to alkaline region. | 2015-11-05 |
20150316542 | Reference and Normalisation Method for Use With Bead-Based Immunoassays in a Microfluidic Disc - The invention relates to a microfluidic system and method of processing biological samples in microfluidic system comprising the steps of the steps of positioning at least one detection chamber adapted for receiving particles, said particles comprising a reference label and reporter label, wherein the labels exhibit different wavelength properties when irradiated with light; and normalising the particle reporter label by using any detected magnitude in the measured properties of the reference label. | 2015-11-05 |
20150316543 | METHODS AND REAGENTS FOR THE DETECTION OF BIOMOLECULES USING LUMINESCENCE - The present invention relates to luminescent complexes comprising a charged transfer complex of metal atomic quantum clusters (AQCs) of at least two different sizes and a biotin-binding molecule, preferably streptavidin, and the use thereof for the detection of biotinylated compounds. The invention also relates to the use of conjugates comprising a charged transfer complex of AQCs and a biomolecule and the use thereof for the detection of binding partners of the biomolecule in a sample based on the luminescent properties of the AQCs nanosystems. | 2015-11-05 |
20150316544 | RELEASABLE MAGNETIC CELL CAPTURE SYSTEM - Compositions and methods for capturing specific cell types from a mixture in a liquid suspension of cells are provided. Targeted magnetic nanoparticles of the invention can be utilized to isolate, quantify, and characterize circulating tumor cells from complex body fluids, such as blood. The magnetic nanoparticles are releasable after targeted cells have been isolated, leaving the cells in a viable state for characterization and growth in culture. The targeted magnetic nanoparticles are fabricated using surface-functionalized super paramagnetic nanoparticles that are encapsulated in a biodegradable and biocompatible polymer to form microparticles. The microparticles are rendered target-selective by additional coatings of gelatin and gold nanoparticles which are derivatized with a targeting ligand specific for a targeted cell type. | 2015-11-05 |
20150316545 | ULTRASENSITIVE DETECTION OF A BIOLOGICAL TARGET BY APTAMER-CONJUGATED GOLD NANOPARTICLES - Methods of assaying a biological target are disclosed. The method comprises: (a) providing a sample containing the biological target; (b) providing biotin-labeled first aptamers conjugated to a gold nanoparticle (GNP), and second aptamers conjugated to a magnetic bead, wherein the first and the second aptamers exhibit specific binding affinities to the target; (c) incubating the sample with the first and the second aptamers to obtain target-bound aptamers; (d) separating the target-bound aptamers from unbound aptamers; (e) eluting the first aptamers from the GNP; (f) incubating the eluted biotin-labeled first aptamers with streptavidin-magnetic beads and reporter gold nanoparticles (GNPs) to obtain a complex comprising: the bead, the first aptamers, attached to the bead; and the reporter GNPs captured by the bead through the first aptamers; (g) eluting the reporter GNPs captured; and (h) detecting the target by measuring and analyzing a light-scattering signal of the eluted reporter GNPs. | 2015-11-05 |
20150316546 | SENSOR CHIP - A sensor chip is configured to be used together with probe solution containing a probe for capturing an object substance. The sensor chip includes a substrate, a probe-immobilizing part disposed on an upper surface of the substrate, and a liquid-spread-prevention part disposed around the probe-immobilizing part. The probe-immobilizing part is configured to immobilize the probe by allowing the probe solution to be spotted to the probe-immobilizing part. The liquid-spread-prevention part prevents a liquid from spreading from the probe-immobilizing part. The probe-immobilizing part is made of a porous material having pores provided therein. This sensor chip has high detection sensitivity. | 2015-11-05 |
20150316547 | Electrophoretic Separation Devices and Methods for Using the Same - Electrophoretic separation devices and methods for using the same are provided. Aspects of the devices include a polymeric separation medium that includes a plurality of microwells. Also provided are methods, systems and kits in which the subject devices find use. The devices and methods find use in a variety of different electrophoretic separation applications. | 2015-11-05 |
20150316548 | PROGRANULIN AS MARKER FOR AUTOIMMUNE DISORDERS - The present invention provides for means and method for the detection and/or the quantification of anti-progranulin-autoantibodies in a biological sample of a subject. The present invention also provides for means and method for the detection and/or the quantification of hyper-phosphorylated progranulin in a biological sample of a subject. The present invention further provides for means and methods for the detection of an aberrant conversion pathway of progranulin into granulines in a biological sample of a subject. In fact, the presence of anti-progranulin-autoantibodies and/or hyper-phosphorylated progranulin and/or an aberrant conversion pathway may be indicative that the subject may be suffering from an autoimmune disorder. | 2015-11-05 |
20150316549 | METHOD OF DIAGNOSING BACTERIAL INFECTIONS USING BACTERIAL GLYCOPROTEINS - The present application provides a method of diagnosing bacterial infections using engineered glycoproteins in an immunoassay. The engineered bacterial glycoproteins used in the immunoassay comprise a bacterial antigen covalently attached to a protein via polysaccharyltransferase (PTase)-mediated glycosylation, wherein the bacterial antigen is selected based on the bacterial infection of interest. Antibodies in a bodily fluid of subjects infected with a bacteria will bind to the engineered glycoprotein, and the resulting binding complexes are detected or quantitated. | 2015-11-05 |
20150316550 | Method of Determining the Probability of a Therapeutic Response in Cancer Chemotherapy with Cardiac Glycoside - A prognostic assay and kit and method of use thereof are provided. The kit and assay are used to determine the likelihood of a diseased cell or tissue having a therapeutic response to treatment with a cardiac glycoside in a disease having an etiology associated with excessive cell proliferation. The kit and assay are used to determine the ratio of isoforms of the α subunit of Na, K-ATPase obtained from the diseased cell or tissue. The kit can be used to predict the therapeutic responsiveness of cancer or tumor in a subject to treatment with a cardiac glycoside. The kit and assay can be incorporated in a method of treating a disease or disorder having an etiology associated with excessive cell proliferation with a composition comprising a cardiac glycoside. | 2015-11-05 |
20150316551 | Sumoylation of SERCA2a and Cardiovascular Disease - Methods for treating cardiovascular disease, and in particular heart failure, are provided comprising administering a therapeutically effective amount of a modulator of SERCA2a post-translation modification such as SUMOylation or acetylation. Also provided are methods of treating cardiovascular disease by inhibiting SERCA2a degradation. Further provided are methods of diagnosing a propensity to develop heart failure comprising determining if a SERCA2a mutant is present or determining the level of expression of SUMO1 in cardiomyocytes. The disclosure also provides methods of screening for therapeutics that modulate the post-translational modification of SERCA2a, such as by modulating post-translational SUMOylation and/or acetylation. | 2015-11-05 |
20150316552 | Human Notch Receptor Mutations and Their Use - The present invention provides the identification and characterization of NOTCH mutations associated with enhanced receptor signaling. The present invention provides methods and kits for using the same. The present invention further provides methods of treating cancer in a patient having a solid tumor, wherein the solid tumor cells comprise an elevated level of NOTCH ICD. | 2015-11-05 |
20150316553 | TREATMENT AND DIAGNOSIS OF CANCER - Use of antibodies or binding portions thereof, probes, ligands, or other biological agents which either recognize an extracellular domain of prostate specific membrane antigen (PSMA) or bind to and are internalized with PSMA. These biological agents can be labeled and used for detection of cancerous tissues, particularly cancerous tissues proximate to or containing vascular endothelial cells, which express an extracellular domain of PSMA. The labeled biological agents can also be used to detect normal, benign hyperplastic, and cancerous prostate epithelial cells or portions thereof. They also can be used alone or bound to a substance effective to ablate or kill such cells as a therapy for prostate or other cancers. Also disclosed are four hybridoma cells lines, each of which produces a monoclonal antibody recognizing extracellular domains of PSMA of normal, benign hyperplastic, and cancerous prostate epithelial cells or portions thereof. | 2015-11-05 |
20150316554 | Diagnostic Biomarkers and Therapeutic Targets for Pancreatic Cancer - We identified >40 proteins that elicited at least a 2-fold increase in antibody response post-pancreatic-cancer vaccination, from each of three patients' sera. The antibody responses detected against these proteins in patients with >3 years disease-free survival indicates the anti-tumor potential of targeting these proteins. We found that tissue expression of proteins PSMC5, TFRC and PPP1R12A increases during tumor development from normal to pre-malignant to pancreatic tumor. In addition, these proteins were shown to be pancreatic cancer-associated antigens that are recognized by post-vaccination antibodies in the sera of patients that received the vaccine and have demonstrated a favorable disease free survival. | 2015-11-05 |
20150316555 | DEVICES AND METHODS FOR ENRICHMENT AND ALTERATION OF CIRCULATING TUMOR CELLS AND OTHER PARTICLES - The invention features devices and methods for detecting, enriching, and analyzing circulating tumor cells and other particles. The invention further features methods of diagnosing a condition, e.g., cancer, in a subject by analyzing a cellular sample from the subject. | 2015-11-05 |
20150316556 | SSEA4 AND ST3GAL2 AS CHEMOTHERAPEUTIC DRUG RESPONSE BIOMARKERS - The present invention provides the use of the biomarkers SSEA4 and/or ST3GAL2 for assessing the outcome for chemotherapeutic treatment of a cancer in an individual and methods thereof. | 2015-11-05 |
20150316557 | COUMARIN-BASED FLUOROGENIC AGENTS AND USES THEREOF FOR SPECIFIC PROTEIN LABELLING - There are provided fluorescent labelling agents comprising a dimaleimide core connected to a fluorophore, processes for preparation thereof, and uses thereof for labelling and/or detection of specific protein targets. Fluorescent labelling agents comprising a compound having the structure of Formula I, and salts thereof, are described. | 2015-11-05 |
20150316558 | Fluorescent Chemical Compounds Having High Selectivity for Double Stranded DNA, and Methods for Their Use - Chemical compounds having a high selectivity for double stranded DNA over RNA and single stranded DNA are disclosed. The chemical compounds are stains that become fluorescent upon illumination and interaction with double stranded DNA, but exhibit reduced or no fluorescence in the absence of double stranded DNA. The compounds can be used in a variety of biological applications to qualitatively or quantitatively assay DNA, even in the presence of RNA. | 2015-11-05 |
20150316559 | GLUCOSE SENSOR SIGNAL STABILITY ANALYSIS - Disclosed are methods, apparatuses, etc. for glucose sensor signal stability analysis. In certain example embodiments, a series of samples of at least one sensor signal that is responsive to a blood glucose level of a patient may be obtained. Based at least partly on the series of samples, at least one metric may be determined to assess an underlying trend of a change in responsiveness of the at least one sensor signal to the blood glucose level of the patient over time. A reliability of the at least one sensor signal to respond to the blood glucose level of the patient may be assessed based at least partly on the at least one metric assessing the underlying trend. Other example embodiments are disclosed herein. | 2015-11-05 |
20150316560 | PREDICTION AND PROPHYLACTIC TREATMENT OF TYPE 1 DIABETES - An in vitro method for predicting the onset of type 1 diabetes (T1D) in a subject, comprises the steps of: (a) measuring the concentration of at least one amino acid, amino acid derivative or amino acid metabolite in a biological sample taken from the subject; (b) determining the subject's HLA genotype; (c) assigning the subject's genetic risk of developing T1D on the basis of the subject's HLA genotype; (d) combining the information obtained in step (a) with the information in step (c); and (e) predicting the likelihood of onset of T1D based upon the combination of step (d). The diagnostic method can be used to select target subjects for T1D prophylactic treatment, and as part of a T1D preventative treatment regime for neonates having a likelihood of developing childhood T1D. | 2015-11-05 |
20150316561 | METHODS AND COMPOSITIONS RELATED TO MODULATORS OF EUKARYOTIC CELLS - Methods for Identifying protein modulators of eukaryotic cells by expressing a combinatorial library of potential agonists inside a eukaryotic cell and then directly selecting for an agonist of a target molecule. Some methods involve co-culturing a cell expressing a combinatorial library of potential agonists and a second cell, and then selecting agents that modulate a phenotype of or a desired cellular response in the second cell. Preferably, the agonists are antibodies introduced into and expressed in the starting cells, such as agonist anti-EpoR, anti-TpoR, or G-CSFR antibodies. Also disclosed are methods for selecting from combinatorial antibody libraries bispecific antibodies that can regulate cell phenotypes. | 2015-11-05 |
20150316562 | METHOD AND BIOMARKERS FOR THE DETECTION OF DENGUE HEMORRHAGIC FEVER - The present invention provides methods for detecting, analyzing, and identifying biomolecules used to identifying patient with dengue-like symptom who are at risk of DHF. The inventive method comprises detecting in a sample from a subject dengue infected patient one or more biomarkers selected from the group consisting of IL-10, fibrinogen, C4A, immunoglobulin, tropomyosin, and three isoforms of albumin, and which are used in a predictive MARS model to detect patients with risk of developing DHF. | 2015-11-05 |
20150316563 | METHOD FOR THE DIAGNOSIS OF METACHROMATIC LEUKODYSTROPHY - The present invention is related to a method for diagnosing metachromatic leukodystrophy in a subject comprising a step a), wherein the step a) comprises detecting a biomarker in a sample from the subject, wherein the sample is selected from the group consisting of blood, dried blood, serum and plasma and wherein the biomarker is different from an enzyme. | 2015-11-05 |
20150316564 | Blood Analyzing Device for Malaria Analysis - A blood analyzing device ( | 2015-11-05 |
20150316565 | Methodologies and Reagents for Detecting Fibrinolysis and Hyperfibrinolysis - In some embodiments, the invention provides methods for detecting fibrinolysis or hyperfibrinolysis in a blood sample from a patient. The method includes subjecting a first portion of a blood sample comprising reduced platelet function to viscoelastic analysis in the absence of an inhibitor of fibrinolysis to obtain the coagulation characteristic of the first portion at the time point; and subjecting a second portion of the blood sample comprising reduced platelet function to viscoelastic analysis in the presence of an inhibitor of fibrinolysis to obtain a coagulation characteristic of the second portion at a time point; wherein a difference between the coagulation characteristic of the first portion and the coagulation characteristic of the second portion indicates fibrinolysis or hyperfibrinolysis in the blood sample. | 2015-11-05 |
20150316566 | HDL THERAPY MARKERS - The present application relates to companion diagnostic assays for therapeutic agents that mimic HDL or elevate HDL expression levels. The present application also related to methods of treatment of familial hypoalphalipoproteinemias. | 2015-11-05 |
20150316567 | METHODS FOR ASSESSING IMMUNOGENICITY - This disclosure relates to methods for detecting the potency of a drug preparation and/or detecting antibodies in a host reactive against one or more antigens. | 2015-11-05 |
20150316568 | Method for Screening Lyophilized Parenteral Formulations - Embodiments of the present invention feature methods for screening parenteral formulations which require small quantities of drug and rapid results. The method features steps of identifying one or more solutions for reconstitution and applying the solutions to lyophilized drug, excipient and diluent combinations. | 2015-11-05 |
20150316569 | SAMPLE ANALYZER - A sample analyzer is disclosed that includes: a memory configured to store a record of maintenance already performed on the sample analyzer; a display; and a display control configured to control the display to display a first table which chronologically shows the record of maintenance already performed, wherein the first table is assigned a predetermined term, in the table the term is divided into a plurality of sections. | 2015-11-05 |
20150316570 | AUTOMATED ANALYZER - A control section causes one dispensing mechanism of either a reagent dispensing mechanism or a sample dispensing mechanism to first discharge a predetermined amount of a liquid into the reaction container, and then, with respect to the cases where the amount of a liquid to be discharged by the other dispensing mechanism is larger or smaller than the amount of the liquid in the reaction container, causes the other dispensing mechanism to discharge the liquid such that the discharge speed in the case where the amount of the liquid to be discharged is larger is decreased relative to the discharge speed in the case where the amount of the liquid to be discharged is smaller. | 2015-11-05 |
20150316571 | FLUID SAMPLE SYSTEM AND METHOD - A fluid sample system includes a control system that operates in the hazardous area and controls one or more valves and optionally receives outputs from one or more transducers and optionally one or more sensors. The fluid sample system includes components that operate in a hazardous area and includes a control system that operates in the hazardous area and that controls one or more electrical devices. The control system communicates across a barrier with a system on a safe side of the barrier with as few as two intrinsically safe couplings including a single pneumatic coupling and a communication link coupling. The control system includes an intrinsically safe voltage boost circuit. | 2015-11-05 |
20150316572 | LIGHT SENSOR AND ELECTRONIC DEVICE - A provision of a movement direction determination section for determining that a particular direction is a movement direction of the detection target object, in a case where a second comparator determines that larger than a predetermined threshold value is an absolute value of a ratio of (i) a difference between the photocurrent of the at least two light receiving elements to (ii) a sum of a photocurrent of at least two light receiving elements next to each other along the particular direction. | 2015-11-05 |
20150316573 | TARGET SPEED DETERMINATION DEVICE, TARGET SPEED DETERMINATION METHOD AND PROGRAM, VEHICLE CONTROL DEVICE, AND VEHICLE - In the present invention: a power consumption calculation unit sets target speeds in a plurality of sections of a track; the power consumption calculation unit calculates, on the basis of the target speeds, the power consumption when the track is traveled; a target speed change unit changes combinations of target speeds in the plurality of sections set by the power consumption calculation unit; an evaluation value calculation unit calculates an evaluation value on the basis of an evaluation function for each combination of target speeds; the evaluation function is a function in which the power consumption calculated by the power consumption calculation unit is multiplied by a prescribed weight; and a target speed determination unit sets the combination of target speeds in which the evaluation value is smallest as the target speed of the vehicle in each section. | 2015-11-05 |
20150316574 | DEVICE AND METHOD FOR CONTINUOUSLY MEASURING FLOW RATE NEAR LIQUID STEEL SURFACE - The invention discloses a device for continuously measuring the flow rate of steel melt near surface thereof, wherein the device comprises a flow rate detecting rod ( | 2015-11-05 |
20150316575 | Wake Vortex Avoidance System and Method - A wake vortex avoidance system includes a microphone array configured to detect low frequency sounds. A signal processor determines a geometric mean coherence based on the detected low frequency sounds. A display displays wake vortices based on the determined geometric mean coherence. | 2015-11-05 |
20150316576 | MOTION DIRECTION DETERMINATION AND APPLICATION - This disclosure provides devices, computer programs and methods for determining a motion direction. In one aspect, a mobile device includes one or more sensors configured to measure acceleration data in each of one or more directions. The mobile device also includes one or more processors and a memory storing instructions that, when executed by the one or more processors, implement a motion direction estimation module. The motion direction estimation module is configured to identify a use case for the mobile device based at least in part on the acceleration data. The motion direction estimation module also is configured to select a set of one or more parameters based on the identified use case. The motion direction estimation module is further configured to calculate an estimated motion direction of the mobile device based on the acceleration data and the respective set of parameters corresponding to the identified use case. | 2015-11-05 |
20150316577 | MOTION DIRECTION DETERMINATION AND APPLICATION - This disclosure provides devices, computer programs and methods for determining a motion direction. In one aspect, a mobile device includes sensors for measuring acceleration data. The mobile device also includes a processor and memory that implement a plurality of motion direction estimation modules for calculating a plurality of respective motion directions. Each of the motion direction estimation modules uses a respective set of parameters and calculates the respective motion direction based on the acceleration data and the respective set of parameters. The modules also include a plurality of reliability metric computation modules for determining a plurality of respective reliability metrics for the respective estimated motion directions. The modules also include a selection module for identifying the reliability metric that indicates the greatest reliability, identifying the corresponding motion direction, and generating a resultant motion direction. In some implementations, the selection module selects the identified motion direction as the resultant motion direction. | 2015-11-05 |
20150316578 | MOTION DIRECTION DETERMINATION AND APPLICATION - This disclosure provides devices, computer programs and methods for determining a motion direction. In one aspect, a mobile device includes sensors for measuring acceleration data. The mobile device also includes a processor and a memory that implement a motion direction estimation module configured to determine a primary axis of motion. The motion direction estimation module also determines a motion direction along the primary axis. The determination includes fitting the acceleration data, or data derived therefrom, to a bimodal distribution. A first peak of the bimodal distribution corresponds to a first motion direction along the primary axis, and a second peak corresponds to a second motion direction opposite the first. The motion direction estimation module is configured to estimate the motion direction based on the bimodal distribution. In some implementations, the motion direction estimation module selects the motion direction corresponding to the higher of the peaks as the estimated motion direction. | 2015-11-05 |
20150316579 | MOTION DIRECTION DETERMINATION AND APPLICATION - This disclosure provides devices, computer programs, and methods for estimating reliability metrics. In one aspect, a mobile device includes sensors for measuring acceleration data, a processor, and a memory storing instructions that implement a plurality of modules. The modules include a motion direction estimation module for estimating a motion direction based on the acceleration data. The modules also include a reliability metric computation module for estimating reliability metrics. For example, the reliability metric computation module can estimate a first reliability metric based on a process used to estimate the motion direction, a second reliability metric based on a measure of stability of the device, and a third reliability metric based on a measure of consistency in the estimated motion direction over a period. The reliability metric computation module calculates a composite reliability metric that indicates a measure of certainty in the estimated motion direction based on the estimated reliability metrics. | 2015-11-05 |
20150316580 | OPTOMECHANICAL SENSOR FOR ACCELEROMETRY AND GYROSCOPY - Embodiments of the present disclosure are directed towards a micro-electromechanical system (MEMS) sensing device, including a laser arrangement configured to generate a light beam, a first waveguide configured to receive and output a first portion of the light beam, and a second waveguide having a section that is evanescently coupled to the first waveguide and configured to receive and output a second portion of the light beam. The section of the second waveguide is configured to be movable substantially parallel to the first waveguide, wherein a movement of the section of the second waveguide may be caused by an inertial change applied to the sensing device. The movement of the section may cause a detectable change in light intensity between the first and second portions of the light beam. Based on the detected change, the inertial change may be determined. Other embodiments may be described and/or claimed. | 2015-11-05 |
20150316581 | CAPACITIVE MICROMECHANICAL SENSOR STRUCTURE AND MICROMECHANICAL ACCELEROMETER - The invention relates to a capacitive micromechanical sensor structure comprising a stator structure rigidly anchored to a substrate and a rotor structure movably anchored by means of spring structures to the substrate. The stator structure has a plurality of stator finger support beams and the rotor structure has a plurality of rotor finger support beams. Stator fingers along the stator finger support beam of the stator structure extend into rotor gaps along the rotor finger support beam of the rotor structure, and rotor fingers along the rotor finger support beam of the rotor structure extend into stator gaps along the stator finger support beam of the stator structure. | 2015-11-05 |
20150316582 | FUNCTIONAL ELEMENT, PHYSICAL QUANTITY SENSOR, ELECTRONIC APPARATUS AND MOBILE ENTITY - An acceleration sensor includes a substrate, a support beam, a weight body a stationary section and an engaging section. The weight body is divided into a first weight section and a second weight section based on the support beam as a boundary line, and the first weight section and the second weight section have different weights from each other. The first weight section and the second weight section include a facing section which faces a side of the engaging section opposite to a side facing the support beam. In an X axis direction intersecting the Y axis direction, if a distance between a corner section of the engaging section in the vicinity of one end portion and the support beam is L | 2015-11-05 |
20150316583 | SEMICONDUCTOR TESTING STRUCTURES AND FABRICATION METHOD THEREOF - A method is provided for fabricating a semiconductor testing structure. The method includes providing a substrate having a to-be-tested device structure formed on a surface of the substrate, a dielectric layer formed on the surface of the substrate and a surface of the to-be-tested structure, and conductive structures and an insulation layer electrically insulating the conductive structures formed on a first surface of the dielectric layer. The method also includes planarizing the conductive structures and the insulation layer to remove the conductive structures and the insulation layer until the first surface of the dielectric layer is exposed; and bonding the first surface of the dielectric layer with a dummy wafer by an adhesive layer. Further, the method includes removing the substrate to expose a second surface relative to the first surface of the dielectric layer of the dielectric layer and a surface of the to-be-tested device structure. | 2015-11-05 |
20150316584 | SENSOR FOR OUTPUTTING AN ELECTRIC SIGNAL ON THE BASIS OF A DETECTED PHYSICAL VARIABLE - A sensor for outputting an electrical signal on the basis of a detected physical variable, including: a measuring circuit accommodated in a circuit housing and capable of contacting an external circuit by an electric signal connection; and a protective body consisting of a protective compound with an opening, the compound surrounding the circuit housing and the opening exposing part of the circuit housing. The surface of the circuit housing has a moulded element which is surrounded by the protective compound. | 2015-11-05 |
20150316585 | MEASURING ARRANGEMENT FOR MEASURING AN EFFECTIVE VALUE OF AN AC VOLTAGE IN A HANDHELD POWER TOOL - The hand-held power tool according to the invention has a measuring system for determining an effective value of an alternating voltage (U), which is fed via an external conductor (L) with respect to a neutral conductor (N). A regulated direct voltage source ( | 2015-11-05 |
20150316586 | SYSTEMS AND METHODS FOR HIGH VOLTAGE BRIDGE BIAS GENERATION AND LOW VOLTAGE READOUT CIRCUITRY - A multi voltage sensor system includes one or more charge pumps, a sensor bridge and readout circuitry. The one or more charge pumps are configured to provide a high voltage. The sensor bridge is biased by the high voltage and is configured to provide sensor values. The readout circuitry includes only low voltage components. The readout circuitry is configured to receive the sensor values. | 2015-11-05 |
20150316587 | METHODS AND DEVICES FOR DETERMINING ROOT MEAN SQUARE OF A DELTA-SIGMA MODULATED SIGNAL - Described is a method and devices to determine root-mean-square of a delta- sigma modulated signal. The method includes filtering the delta-sigma modulated signal to produce a multi-bit filtered signal, delaying a copy of the delta-sigma modulated signal by a fixed number of samples to align with the filtered input, setting a sign of each multi-bit value of the multi-bit filtered signal based upon a corresponding sample value of the delayed copy of the delta-sigma modulated signal, to generate a hybrid signal, summing the hybrid signal to produce a summed signal, and determining the average of the summed signal and the square root of the average to produce a root-mean-square value. | 2015-11-05 |
20150316588 | Method and Apparatus for Current-Output Peak Detection - A method and apparatus for a current-output peak detector. A current-output peak detector circuit is disclosed and works in two phases. The peak detector circuit includes switches to switch the peak detector circuit from the first phase to the second phase upon detection of the peak voltage of an input voltage signal. The peak detector generates a current output with a high degree of accuracy in the second phase. | 2015-11-05 |
20150316589 | RECEPTACLE INDICATING RELATIVE LEVEL OF CURRENT OR ENERGY - A smart receptacle is for a number of loads. The smart receptacle includes separable contacts; an operating mechanism structured to open and close the separable contacts; and a number of current sensors structured to sense current flowing through the separable contacts to one of the number of loads. A number of indicators indicate a relative level of the sensed current or corresponding energy. A processor inputs the sensed current, determines the relative level of the sensed current or the corresponding energy, and controls the number of indicators to indicate the relative level of the sensed current or the corresponding energy. | 2015-11-05 |