44th week of 2021 patent applcation highlights part 38 |
Patent application number | Title | Published |
20210341418 | DETECTION OF OXIDANT IN SEAWATER - An embodiment provides a method for measuring total oxidant in a seawater sample, comprising: forming a seawater solution and a formed iodine by introducing a buffer and an iodide reagent to a seawater sample, wherein the seawater sample contains an amount of oxidant; placing the seawater solution in a measurement device, wherein the measurement device comprises a boron doped diamond working electrode reacting with the seawater solution and the formed iodine, wherein an electrochemical process reduces the formed iodine to iodide; and measuring the amount of total oxidant in the seawater sample by measuring, using the measurement device, an amount of iodide in the seawater sample. Other aspects are described and claimed. | 2021-11-04 |
20210341419 | CAPILLARY ARRAY UNIT - Provided is a capillary array unit configured to facilitate attaching/detaching operation. A capillary array unit includes a capillary, a load header provided at one end of the capillary, a capillary head provided at the other end of the capillary, a detection section provided at a portion of the capillary, and a holder holding the capillary. The holder includes a first holding section holding the capillary in a curved shape, a second holding section linearly holding the capillary, and a guide to move the second holding section in a predetermined direction. | 2021-11-04 |
20210341420 | LASER ILLUMINATION TECHNIQUES FOR CAPILLARY ELECTROPHORESIS - A laser-line-generating system generates and process a laser light to illuminate a capillary array. The laser-line-generating system includes a laser-light source, focusing optics, a first optical scanner, and a second optical scanner. The laser-light source outputs a first laser light. The focusing optics receives the first laser light and reduces a beam width of the first laser light. The first optical scanner receives the first laser light and output a first optical-scanner-outputted light by varying an angle of outputted light along a first dimension. The second optical scanner receives the first optical-scanner-outputted light and outputs a second optical-scanner-outputted light by varying an angle of outputted light along a second dimension. The second optical-scanner-outputted light includes a line with dimensional components in both the first dimension and the second dimension. | 2021-11-04 |
20210341421 | NANOPORE FUNCTIONALITY CONTROL - A method is provided of controlling the functionality of a substrate containing at least one nanopore. The method includes the steps of: introducing to the substrate a solution containing a molecular construct having a body formation which defines an aperture and a tail formation extending from the body formation; applying a potential difference across the substrate to thread the tail formation through the nanopore thereby docking the molecular construct to the substrate with the aperture aligned with the nanopore such that the sleeve formation lines the nanopore; and expelling the molecular construct from the substrate by varying the potential difference. A DNA construct for docking to a substrate having a nanopore is also provided, the construct having a body formation which defines an aperture, and a tail formation extending from the body formation for threading through the nanopore to dock the construct to the substrate with the aperture and nanopore in alignment. | 2021-11-04 |
20210341422 | INTEGRATED MICRO-PHOTOIONIZATION DETECTOR WITH AN ULTRATHIN ULTRAVIOLET TRANSMISSION WINDOW - An integrated microfluidic photoionization detector (PID) is provided including a microfluidic ionization chamber a microfluidic ultraviolet radiation chamber that is configured to generate ultraviolet photons. An ultrathin transmissive window is disposed between the microfluidic ionization chamber and the microfluidic ultraviolet radiation chamber that permits the ultraviolet photons to pass from the microfluidic ultraviolet radiation chamber into the microfluidic ionization chamber. Detection systems for one or more VOC analytes are also provided that include a gas chromatography (GC) unit including at least one gas chromatography column and an integrated microfluidic photoionization detector (PID) disposed downstream of the gas chromatography (GC) unit. | 2021-11-04 |
20210341423 | GATE DETECTION ROBOT BASED ON GIANT MAGNETORESISTANCE ELEMENT AND DETECTION METHOD - A gate detection robot based on a giant magnetoresistance element includes a support, a guide wheel, and two driving wheels are provided at the bottom of the support. The support is provided with a controller, a range-based localization module, and a magnetic flaw detection sensor based on the giant magnetoresistance element. The magnetic flaw detection sensor includes an excitation mechanism, a giant magnetic sensor, and two magnetic concentrators. During detection, the excitation mechanism magnetizes a gate with a magnetic field as a medium. When the surface of the gate has a defect, the magnetic conductivity of the local area is reduced and the magnetic resistance is increased so that magnetic lines are distorted and diffused outside the gate to form a detectable leakage magnetic field signal, the signal is transmitted to the controller, so that the controller obtains a specific location of the detection robot. | 2021-11-04 |
20210341424 | DEVICE FOR DETERMINING INFORMATION OF A SUBSTANCE IN A MATTER - A device for determining information of a substance in a matter comprising a substrate layer; an inter-layer dielectric disposed on the substrate layer; an electronic circuitry substantially formed in the inter-layer dielectric and includes a plurality of metal layers with at least one metal layer being used as an inner electrode, a sensing instrument having at least one sensing component that includes a piezoelectric layer and the inner electrode that is positioned adjacent to an inner surface of the piezoelectric layer, and at least one binding layer disposed on the inter-layer dielectric for binding the substance, wherein the sensing component allows the device to determine the information of the substance upon detecting presence of the substance at the binding layer. | 2021-11-04 |
20210341425 | MEASUREMENT DEVICE AND MEASUREMENT METHOD - A measurement device includes a sensor that detects a particular substance, a storage unit that stores calibration data that indicate a relationship between a measurement value of the particular substance and an output of the sensor, and a calculation unit that calculates the measurement value of the particular substance from the calibration data based on the output of the sensor. The calculation unit produces a first waveform where a plurality of first outputs of the sensor are normalized, produces a plurality of second waveforms where a plurality of second outputs of the sensor that are included in the calibration data are normalized. The calculation unit calculates a measurement value of the particular substance based on the first waveform and the plurality of second waveforms. | 2021-11-04 |
20210341426 | INTERNAL STATE DETECTOR AND VEHICLE - A detector that detects an internal state of a plate-shaped object including a fiber-reinforced resin. The detector includes an exciter that applies, to a surface of the object, ultrasonic vibrations of Lamb waves, in a selected frequency range where only a zero-order fundamental wave symmetric mode and a zero-order fundamental wave asymmetric mode of the Lamb waves appear, a vibration detector that detects the applied ultrasonic vibrations propagating in the object, and an internal state estimation calculator that estimates the internal state of the object, by obtaining a propagation time of the ultrasonic vibrations propagating in the object corresponding to each frequency of the Lamb waves, based on the detection result of the vibration detector, estimating the internal state based on a delay time of the propagation time relative to a reference propagation time of the object for each frequency in the selected frequency range, and outputting the estimated internal state. | 2021-11-04 |
20210341427 | TRANSDUCER, DEVICE AND METHOD FOR MONITORING INTEGRITY OF AN ADHESIVE BOND - A transducer for monitoring integrity of an adhesive bond between a first element and a second element, the transducer comprising: a transducing adhesive, the transducing adhesive provided to act as at least one of: an actuator to convert an electrical signal to an acoustic signal and a sensor to convert an acoustic signal to an electrical signal; and an electrode provided on the transducing adhesive, the electrode provided to perform at least one of: providing an electrical signal to the transducing adhesive and receiving an electrical signal from the transducing adhesive; wherein, in use, the transducer is provided at least partially in the adhesive bond between the first element and the second element, and the acoustic signal is passed through the adhesive bond. | 2021-11-04 |
20210341428 | APPARATUSES, SYSTEMS, AND METHODS FOR DETECTING KISSING BONDS IN BONDED JOINTS - Disclosed herein is a detection assembly for detecting kissing bonds in a bonded joint of a part. The detection assembly comprises an electromagnetic shockwave generator that is configured to generate an electromagnetic shockwave through a target portion of the bonded joint. The electromagnetic shockwave has an intensity sufficient to induce a separation of a kissing bond in the target portion of the bonded joint and insufficient to induce a separation of a healthy bond, adjacent the kissing bond, in the target portion. The detection assembly also comprises an ultrasonic sensor that is configured to generate a transmitted ultrasonic pulse, direct the transmitted ultrasonic pulse into the target portion of the bonded joint, and receive a received ultrasonic pulse from the target portion of the bonded joint in response to the electromagnetic shockwave generator generating the electromagnetic shockwave through the target portion of the bonded joint. | 2021-11-04 |
20210341429 | Phase Velocity Imaging Using an Imaging System - Described here are systems and methods for phase velocity imaging using an imaging system, such as an ultrasound system, an optical imaging system (e.g., an optical coherence tomography system), or a magnetic resonance imaging system. In general, systems and methods for constructing phase velocity images (e.g., 2D images, 3D images) from propagating mechanical wave motion data are described. The systems and methods described in the present disclosure operate in the frequency domain and can be implemented using a single frequency or a band of selected frequencies. If there are multiple mechanical wave sources within the field-of-view, directional filtering may be performed to separate mechanical waves propagating in different directions. The reconstructions described below can be performed for each of these directionally filtered components. | 2021-11-04 |
20210341430 | SYSTEMS AND METHODS FOR PREDICTIVE DIAGNOSTICS FOR MECHANICAL SYSTEMS - A predictive diagnostics system for monitoring mechanical seals. The system autonomously detects a loss of lubrication within a sliding seal interface of a mechanical seal, the system including a loss of lubrication failure mode logic module configured to monitor data sensed by one or more sensors and diagnose conditions relating to a loss of lubrication within the sliding seal interface, and a plurality of other failure mode logic modules configured to monitor data sensed by the one or more sensors and diagnose conditions relating to specific types of mechanical failures known to occur in mechanical seal systems, the loss of lubrication failure mode logic module configured to determine which of the plurality of other failure mode logic modules are activated during the diagnosis of conditions related to a loss of lubrication within the sliding seal interface. | 2021-11-04 |
20210341431 | ULTRASONIC DRY COUPLED WHEEL PROBE WITH A RADIAL TRANSDUCER - An ultrasonic dry coupled wheel probe with radial transducers emit ultrasound in substantially all radial directions relative to a longitudinal axis. The probe does not require normalization and is efficient in directing ultrasound to a surface being inspected. The probe has a wheel composed of rubber or other materials for acoustically dry coupling the transducer to the surface. A first transducer is composed of a piezoelectric material so that the transducer receives an electrical signal, vibrates, and generates and transmits sound, such as ultrasound. Similarly, a second transducer receives sound such as ultrasound, vibrates, and generates a corresponding electrical signal. The transducer arrangement both transmits ultrasound to the surface and receives the reflection of the ultrasound from the surface. An acoustic barrier separates the transmitting component from the receiving component. The transducer has annular electroplates adjacent to the piezoelectric material. The two transducers can comprise a single, integrated transducer module. | 2021-11-04 |
20210341432 | Electro-Magnetic Acoustic Transducer (EMAT) having Electromagnet Array for Generating Configurable Bias Magnetic Field Patterns - An electro-magnetic acoustic transducer (EMAT) having an electromagnet array is provided. The electromagnet array includes electromagnets. Each electromagnet includes a magnetic core and a wound coil wrapped around the magnetic core. The electromagnet array generates bias magnetic fields having different patterns when the wound coils are energized differently. For instance, the electromagnet array generates a bias magnetic field having a given pattern, for the EMAT to transmit a first type of ultrasonic wave such as shear-horizontal wave, when the wound coils are energized in a given manner; and generates a bias magnetic field having a different pattern, for the EMAT to transmit a second type of ultrasonic wave such as a Lamb wave, when the wound coils are energized in a different manner. | 2021-11-04 |
20210341433 | Thermal Emitter With Embedded Heating Element - A thermal emitter includes a freestanding membrane supported by a substrate, wherein the freestanding membrane includes in a lateral extension a center section, a conductive intermediate section and a border section, wherein the conductive intermediate section laterally surrounds the center section and is electrically isolated from the center section, the conductive intermediate section including a conductive semiconductor material that is encapsulated in an insulating material, wherein the border section at least partially surrounds the intermediate section and is electrically isolated from the conductive intermediate section, and wherein a perforation is formed through the border section. | 2021-11-04 |
20210341434 | Photoacoustic Detector - A photoacoustic detector includes an emitter, an acoustic resonator having a single-pass cavity with a transparent wall, and an acoustic sensor. The emitter is arranged adjacent to the transparent wall and is configured to emit modulated electromagnetic radiation that enters the acoustic resonator through the transparent wall in a direction that intersects with a longitudinal axis of the cavity. | 2021-11-04 |
20210341435 | TIME-CORRECTED GAIN METHOD IMPLEMENTED IN AN ULTRASONIC SCANNER - An ultrasonic scanner acquires a gain profile including gain values for corresponding travel times in ultrasonic echoes reflected by a reference object. An ultrasonic probe signal is sent toward a test object. In response, an ultrasonic echo reflected by the test object is received at the scanner. A time of arrival of the echo is estimated. The gain profile is aligned with the echo according to the estimated time of arrival of the echo. The echo is amplified using the aligned gain profile and the amplified echo is digitized before being attenuated using the aligned gain profile. An actual time of arrival of the echo is calculated based on the attenuated digitized echo. The gain profile is re-aligned with the attenuated digitized echo according to the actual time of arrival of the echo. The attenuated digitized echo is re-amplified using the re-aligned gain profile to obtain a gain-corrected echo. | 2021-11-04 |
20210341436 | IMAGE RECONSTRUCTION METHOD BASED ON A TRAINED NON-LINEAR MAPPING - The present invention concerns an array processing image reconstruction method comprising: receiving a set of echo waveforms as measurements from the object of interest; defining a measurement model linking an unknown image of the object to the measurements; defining a data fidelity functional using the measurement model; defining a regularisation functional using a trained non-linear mapping, the regularisation functional comprising prior knowledge about the unknown image; defining an optimisation problem involving the data fidelity functional and the regularisation functional for obtaining a first image estimate of the unknown image; and solving the optimisation problem to obtain the first image estimate. | 2021-11-04 |
20210341437 | ESTABLISHING FLUIDIC CONNECTIONS BETWEEN CHROMATOGRAPHY COMPONENTS - A clamp assembly includes a rail extending along the length and configured to receive a first fluidic assembly, and a carriage movably attachable to the rail such that the carriage moves along the rail, the carriage configured to receive a second fluidic assembly, the carriage including an actuator and a stop mechanism. The stop mechanism is configured to selectively prevent and allow movement of the carriage relative to the rail. The stop mechanism is configured to be independently operable from the actuator assembly, and the actuator is configured: to move a chromatography column received by the clamp assembly relative to the rail to create a first fluid tight seal between the chromatography column and the first fluidic assembly, and move the second fluidic assembly relative to the carriage body to create a second fluid tight seal between the second fluidic assembly and the chromatography column. | 2021-11-04 |
20210341438 | THERMAL CONDUCTIVITY DETECTOR AND GAS CHROMATOGRAPH INCLUDING SAME - A thermal conductivity detector includes a first pipe path that houses a filament, a second pipe path and a third pipe path that connects the first pipe path to the second pipe path. In the third pipe path, first, second and third gas lead-in portions are arranged in this order from the first pipe path toward the second pipe path. A carrier gas is led to the first and third gas lead-in portions alternately, and a sample gas is led to the second gas lead-in portion. The distance between the second and third gas lead-in portions is equal to or smaller than 1.3 times of a maximum dimension of an opening formed at the second gas lead-in portion. At least part of the third pipe path between the second gas lead-in portion and the third gas lead-in portion has a cross sectional area that is equal to or smaller than an area of the opening formed at the second gas lead-in portion. | 2021-11-04 |
20210341439 | OPEN PORT SAMPLING INTERFACE - A system for sampling a sample material includes a probe which can have an outer probe housing with an open end. A liquid supply conduit within the housing has an outlet positioned to deliver liquid to the open end of the housing. The liquid supply conduit can be connectable to a liquid supply for delivering liquid at a first volumetric flow rate to the open end of the housing. A liquid exhaust conduit within the housing is provided for removing liquid from the open end of the housing. A liquid exhaust system can be provided for removing liquid from the liquid exhaust conduit at a second volumetric flow rate. A droplet dispenser can dispense drops of a sample or a sample-containing solvent into the open end of the housing. A sensor and a processor can be provided to monitor and maintain a liquid dome present at the open end. | 2021-11-04 |
20210341440 | Systems and Methods for Pesticide Detection - This disclosure provides quantitative, rapid, and reliable LC-MS/MS methods for analyzing panels of pesticides and mycotoxins in various samples, including very hydrophobic and chlorinated compounds normally analyzed on a GC-MS/MS system. The methods can be carried out using a single instrument and can detect and quantify levels of the pesticides and mycotoxins that are well below action limits specified by U.S. states (e.g., California) and other countries (e.g., Canada) for these compounds in cannabis products. | 2021-11-04 |
20210341441 | ANALYSIS ASSISTANCE DEVICE, ANALYSIS ASSISTANCE METHOD AND NON-TRANSITORY COMPUTER READABLE STORAGE MEDIUM RECORDING ANALYSIS ASSISTANCE PROGRAM - An analysis assistance device includes an estimator that estimates distribution of measurement quality index data using a plurality of analysis condition data to be provided to an analysis device and a plurality of measurement data obtained in the analysis device based on the plurality of analysis condition data, and a measurement quality index outputter that outputs for display a region where the measurement quality index data is not less than a predetermined threshold value as a design space, and the measurement quality index outputter outputs the region of the design space in an enlarged manner by cutting off at least part of a region other than the design space in a distribution region of the measurement quality index data. | 2021-11-04 |
20210341442 | SOIL ANALYIS COMPOSITIONS AND METHODS - Compositions for testing soil to measure one or more of the following properties of soil: pH, buffer pH, potassium, phosphorus, calcium, and/or magnesium. Test methods for testing soil to measure one or more of the following properties of soil: pH, buffer pH, potassium, phosphorus, calcium, and/or magnesium. A multichamber cartridge containing two or more of the compositions in separate chambers. | 2021-11-04 |
20210341443 | CARBON MONOXIDE SENSOR FOR AN ENGINE ASSEMBLY - An engine assembly includes an internal combustion engine and a carbon monoxide (CO) sensor unit. The CO sensor unit includes a CO sensor controller including a CO sensing circuit configured to detect a level of CO and a shutdown circuit. The shutdown circuit is configured to receive a detected level of CO and calculate a trailing window average of the detected level of CO. The trailing window average includes an average of the detected level of CO over a predetermined sampling window. The shutdown circuit is further configured to determine whether to initiate a shutdown of the internal combustion engine based on at least the calculated trailing window average and a predetermined trailing window average threshold and initiate the shutdown of the internal combustion engine based on determining that the trailing window average exceeds the predetermined trailing window average threshold. | 2021-11-04 |
20210341444 | GAS SAMPLING WITH CONTROLLED HUMIDITY - A sensor system ( | 2021-11-04 |
20210341445 | METHOD FOR MONITORING CHANGE OF VEGETATION WATER CONSERVATION - The present invention relates to a method for monitoring a change of vegetation water conservation. The method includes: obtaining global land water storage change data, precipitation, actual evapotranspiration, soil moisture storage, snowmelt, snow water storage, surface water storage, groundwater storage, change in surface and groundwater resources, litterfall interception water storage, average natural water content, maximum water holding capacity and litterfall accumulation; preprocessing the above data, and calculating a change of vegetation canopy water storage; calculating a change of litterfall interception water storage; calculating a change of soil moisture storage; and determining a water conservation change according to the change of vegetation canopy water storage, the change of litterfall interception water storage and the soil moisture change. The method provides new technical support and reference for the evaluation of ecological effects and water conservation during ecological restoration. | 2021-11-04 |
20210341446 | DIAGNOSTIC ASSAY FOR RUMEN UNDERGRADED PROTEIN DETECTION - A diagnostic assay to determine a percentage rumen undegraded protein in a food product by comparing the percentage of modified protein content to the total crude protein content of the food product. The total crude protein content extracted from a food product sample prior to conducting gel electrophoresis to separate modified protein content from the total crude protein content. The gel band intensities of the separated protein contents analyzed to enumerate a ratio that is used to derive a correlated percentage numen undegraded protein for a given food product sample. The diagnostic assay capable of being provided onsite for quick, cost-efficient and accurate results. | 2021-11-04 |
20210341447 | MILKING SYSTEM WITH SAMPLING DEVICE - A milking system includes a milking device, a milk line for carrying milk from the milking device, and a sampling unit that is arranged to take a sample from the milk line and to test the sample for the presence or concentration of at least one substance. The sampling unit is provided with a control unit and a housing. The housing includes therein a supply reel with a tape that carries reagent, and a sample supplier to supply, under control of the control unit, a part of the sample to the reagent on the tape. The sampling unit further includes a tape displacer displacing the tape under control of the control unit, a sample analyser, and a used tape collector device collecting tape with reagent to which a sample has been supplied. The supply reel at a surface thereof includes a desiccant, or is completely made of a desiccant material. This provides such a large volume of desiccant that the correspondingly high moisture absorption capacity ensures along uninterrupted useful life of the sampling unit, and thus of the milking system. | 2021-11-04 |
20210341448 | SCREENING METHOD FOR THERAPEUTIC DRUG OR PROPHYLACTIC DRUG FOR TAUOPATHY AND DIAGNOSTIC METHOD FOR TAUOPATHY - Provided is a screening method for an agent for treating or preventing tauopathy, the method comprising (1) a step of contacting an NMDA-type glutamate receptor with a tau oligomer in the presence or absence of a candidate compound, and (2) a step of evaluating a direct binding of the tau oligomer to the NMDA-type glutamate receptor. Further provided is a test method for tauopathy, the method comprising (1) a step of contacting an NMDA-type glutamate receptor with a sample isolated from a subject, and (2) a step of quantifying tau oligomers directly binding to the NMDA-type glutamate receptor. | 2021-11-04 |
20210341449 | METHOD OF VALIDATING A WATER DETERMINING DEVICE USING A ROOM TEMPERATURE IONIC LIQUID - A method of validating a water determining device includes the steps of providing a liquid water standard including a room temperature ionic liquid, adding the liquid water standard to the water determining device, and determining the amount of water in the liquid water standard utilizing the water determining device thereby validating the water determining device. | 2021-11-04 |
20210341450 | CHEMICAL SENSOR DEVICES AND METHODS FOR DETECTING CHEMICALS IN FLOW CONDUITS, POOLS AND OTHER SYSTEMS AND MATERIALS USED TO HARNESS, DIRECT, CONTROL AND STORE FLUIDS - A monitoring system and method for any type of fluid system. Exemplary fluid systems include: sanitary and/or storm sewer systems; hydrological power generation, heating and cooling systems; energy exploration, excavation and transmission, specifically hydraulic fracturing known as “fracking”. The system and method utilize chemical sensors and other detection devices, a power source and circuitry to communicate with hand-held devices and/or other local or remote data terminals. Since sewers and other water infrastructure are often used to dispose, transport, store and transform liquids or other materials in addition to human waste and/or waste fluids from other human activity, monitoring effluent and chemical composition of liquids can provide data useful for a wide range of purposes. | 2021-11-04 |
20210341451 | METHOD AND SYSTEM FOR MONITORING AND IDENTIFYING THE WELD QUALITY ON METALLIC COMPONENTS - A method for monitoring and identifying the quality of a welding performed by a welding machinery on a metallic component; the method for monitoring and identifying comprises the steps of: establishing a plurality of classes that describe possible weld defects on the metallic component; identifying a plurality of features that are relative to the functioning of the welding machinery; acquiring the values assumed by the plurality of features during the execution of a current welding on a metallic component; and processing the values assumed by the plurality of features during the execution of the current welding by means of a system for monitoring and identifying the quality to establish the probabilities of the future outcome of the welding of belonging to each of the classes of the plurality of classes. | 2021-11-04 |
20210341452 | AGRICULTURAL SAMPLING SYSTEM AND RELATED METHODS - An automated computer-controlled sampling system and related methods for collecting, processing, and analyzing agricultural samples for various chemical properties such as plant available nutrients. The sampling system allows multiple samples to be processed and analyzed for different analytes or chemical properties in a simultaneous concurrent or semi-concurrent manner. Advantageously, the system can process soil samples in the “as collected” condition without drying or grinding to produce a sample slurry. The system includes a chemical analysis sub-system which processes and analyzes the prepared slurry for quantifying multiple analytes and/or chemical properties of the sample. The chemical analysis sub-system may be embodied in a multi-layered microfluidic manifold processing substrate comprising microfluidic devices which extract and quantify the concentration of analytes or other chemical parameters associated with the sample. The system can be used to analyze various type of agricultural-related samples including soil, vegetation, manure, milk or other. | 2021-11-04 |
20210341453 | Method and System for Estimating Groundwater Recharge Based on Pixel Scale - Methods and systems for estimating a groundwater recharge based on a pixel scale are disclosed. In some embodiments, a method includes the following steps: (1) obtaining an original remote sensing dataset of a climate element in a study area and a pixel area of the study area; (2) calculating a total water resource yield in the study area by a water balance equation according to the original remote sensing dataset of the climate element and the pixel area of the study area; and (3) estimating the groundwater recharge in the study area according to the total water resource yield and the monthly runoff in the study area. The original remote sensing dataset of the climate element includes monthly precipitation per unit pixel area, monthly actual evapotranspiration per unit pixel area, monthly snowmelt per unit pixel area, monthly soil moisture change per unit pixel area, and monthly runoff. | 2021-11-04 |
20210341454 | Method and System for Estimating Surface Runoff Based on Pixel Scale - Methods and systems for estimating a surface runoff based on a pixel scale are disclosed. In some embodiments, the method includes the following steps: (1) calculating a vegetation canopy interception water storage, a litterfall interception water storage, and a soil water storage according to an obtained original remote sensing dataset of a climate element in a study area; (2) calculating a vegetation-soil interception water conservation in the study area based on an established vegetation-soil interception water conservation estimation model according to the vegetation canopy interception water storage, the litterfall interception water storage, the soil water storage, and monthly precipitation; and (3) calculating a surface runoff in the study area based on an established water balance water conservation estimation model according to the monthly precipitation, monthly snowmelt, monthly actual evapotranspiration, and the vegetation-soil interception water conservation in the study area. | 2021-11-04 |
20210341455 | ANALYSIS OF RELEASE-RESISTANT WATER IN MATERIALS AND RELATED DEVICES AND METHODS - Provided herein are new methods of analyzing release-resistant water in materials, such as geologic materials. The methods of the invention typically comprise removal of extraneous water, e.g., by drying, preparing the material for the release of release-resistant water (e.g., by crushing the material, but typically not so greatly as to cause the release of fluid from hermetically sealed components, such as fluid inclusions), and then analyzing the amount of release-resistant water in the sample, either directly in-situ or by the additional step of extracting the release-resistant water and measuring the extraction. The invention also provides new devices and/or systems useful in the performance of such methods. | 2021-11-04 |
20210341456 | ANALYSIS OF A GAS DISSOLVED IN AN INSULATING MEDIUM OF A HIGH-VOLTAGE DEVICE - A method analyses a gas dissolved in an insulating medium of a high-voltage device. The method includes: transferring the dissolved gas by an analysis device into a gas phase to obtain an analysis gas mixture; transporting the analysis gas mixture to an analysis sensor of the analysis device; generating a sensor signal as an output signal of the analysis sensor as a function of a composition of the analysis gas mixture; determining a first intermediate value based on the sensor signal and at least one disturbance value; determining a second intermediate value based on the first intermediate value and at least one specific value of the analysis device; and determining a value for a concentration of the dissolved gas in the insulating medium based on the second intermediate value. | 2021-11-04 |
20210341457 | OIL CONDITION ESTIMATION APPARATUS, VEHICLE CONTROL APPARATUS, VEHICLE CONTROL SYSTEM, AND DATA ANALYSIS APPARATUS - An oil condition estimation apparatus to be applied to a vehicle in which oil is agitated by a rotator includes a storage device and an execution device. The storage device stores mapping data for defining mapping. The mapping includes, as input variables, a speed variable indicating a rotation speed of the rotator, and a pressure variable indicating a pressure of the oil, and includes, as an output variable, an air bubble variable related to air bubbles contained in the oil. The execution device executes an acquisition process for acquiring values of the input variables, and a calculation process for calculating a value of the output variable by inputting, to the mapping, the values of the input variables acquired through the acquisition process. | 2021-11-04 |
20210341458 | Bacterial Biomarker - The Invention relates to bacterial compositions useful in the treatment of cancer. In particular, the compositions can be used as a co-therapy with an immune checkpoint therapy. The invention also relates to methods for identifying a subject that will respond to therapy with an immune checkpoint inhibitor comprising determining the abundance of bacteria in a biological sample from said subject. | 2021-11-04 |
20210341459 | NANOPORE-CONTAINING SUBSTRATES WITH ALIGNED NANOSCALE ELECTRONIC ELEMENTS AND METHODS OF MAKING AND USING SAME - A nanopore-containing substrate includes a substrate, a membrane on the substrate, and at least one nanoscale electronic element disposed on or embedded in the membrane. The membrane defines at least one nanopore. The nanoscale electronic element is aligned with one of the nanopores such that a shortest distance between an edge of the nanoscale electronic element and the edge of the nanopore is less than 50 nm. The nanopores may be formed by etching through a dielectric layer using a solution while applying a voltage to the nanoscale electronic element relative to the solution. The nanopore-containing substrate can be used to detect or sequence a biopolymer, such as a nucleic acid. The nanopore-containing substrate may be used with a biopolymer detection and/or sequencing system. | 2021-11-04 |
20210341460 | COVID-19 TEST - A COVID-19 test method, a test apparatus and a system to control entry to an event uses particle count and spectrographic data. The present embodiments of the invention provide testing apparatuses, systems and methods. These embodiments may provide for an apparatus, system and method for non-invasive respiratory testing. Also, the embodiments may provide for a system and method for determining test sufficiency for a non-invasive respiratory testing apparatus. Also, the embodiments may provide for a system and method for permitting access to a venue for a subject. | 2021-11-04 |
20210341461 | DIAGNOSIS OF CANCER - A method for the early detection and monitoring of the progression of cancer by detecting breath biomarkers is provided. The method comprises assessing the activity of an aldo-keto reductase by measuring the concentration of an exogenous substrate for said enzyme and/or measuring the concentration of a metabolite of said substrate in exhaled breath of a subject. Preferably, the cancer is lung cancer. | 2021-11-04 |
20210341462 | ARTIFICIAL HUMAN PULMONARY AIRWAY AND METHODS OF PREPARATION - The presently disclosed subject matter provides a microfluidic device that can simulate the cross section of the large and small human airways, including the air-exposed epithelial layer, the adjacent surrounding stromal layer, and the blood-facing endothelial layer of near-by vessels in the circulatory system. The microfluidic device can reconstitute the air-liquid interface in the lung and molecular transport characteristics of bronchi and bronchioles in the human pulmonary airways, and provide a more realistic alternative to current in vitro models of airway structures. Additionally, the model can reconstitute the native response of airway tissues to infection by bacterial and viral agents, and also the extravasation of immune cells from the bloodstream and into the stromal and epithelial compartments of the lung in response to an infection. The presently disclosed subject matter also provides microfluidic devices that include multiple chambers assembled by layered stacking or bonding of a basal chamber, a first membrane, an interstitial chamber, a second membrane and an apical chamber. | 2021-11-04 |
20210341463 | Methods for Making Novel Antigen Binding Domains - The present invention relates generally to the field of making novel antigen binding domains against infectious diseases. The present invention also relates to novel CARs that utilize the novel antigen binding domains as an extracellular element. The present invention also relates to use of the novel antigen binding domains as therapeutic agents. | 2021-11-04 |
20210341464 | COLORIMETRIC SENSOR FOR DETECTING BACTERIA AND/OR VIRUSES - A colorimetric sensor for detecting bacteria and/or includes one or more layers having a photonic crystal structure a functional layer comprising a nanomaterial capable of generating bacteria- and/or viruses-bioresponsive surface plasmon overlapping the one or more layers having the photonic crystal structure. The bacteria- and/or viruses-bioresponsive nanomaterial of the functional layer is doped with proteinic substances or antibodies acting as virus receptors, or the colorimetric sensor comprises a receptor layer comprising proteinic substances or antibodies acting as virus receptors. The functional layer and receptor layer overlap each other. Alternatively, or in addition to, the colorimetric sensor comprises a plasmonic nanostructured layer comprising nanostructures such to generate plasmonic colors, overlapping the one or more layers having the photonic crystal structure. | 2021-11-04 |
20210341465 | CHOLESTEROL MEASUREMENT DEVICE - A cholesterol measurement device includes a measuring instrument body; and a light-intensity check member mounted on and integrated with the measuring instrument body. The light intensity check member reflects light emitted from a light-emitting unit, allowing detecting abnormal light intensity and accurate assessing light intensity change, which prevents a measurement value change due to the change in light intensity and improves reliability of the measurement value. The device keeps a measurement unit clean all the time since the measurement unit can be easily cleaned by separating a strip fixation unit, when a specimen flows into the strip fixation unit in which a measurement strip is inserted. | 2021-11-04 |
20210341466 | COLORS FOR CHROMOGENIC IHC AND ISH STAINING WITH MULTI-DYE QUINONE METHIDE AND TYRAMIDE CONJUGATES - Disclosed herein are novel chromogenic conjugates, the conjugates comprising at least two detectable moieties. | 2021-11-04 |
20210341467 | PORTABLE DEVICES AND METHODS FOR DETECTING AND IDENTIFYING COMPOUNDS IN SALIVA - This disclosure relates to portable devices for SARS-COV-2 Antigen (SC2A), a biomarker for the detection of Coronavirus disease 2019 (COVID19). Diagnosis of viral infections such as SARS-COV-2 can be obtained in the early stages of a disease by detection of viral antigens (e.g., SC2A) directly in the clinical specimen. | 2021-11-04 |
20210341468 | FLUORESCENCE COUNTING SYSTEM FOR QUANTIFYING VIRUSES OR ANTIBODIES ON AN IMMOBILIZED METAL SUBSTRATE BY USING AN ANTIGEN-ANTIBODY REACTION - The present invention relates to a system capable of performing simple and rapid inspection of an antigen equivalent to the immune chromatographic method with accuracy good as a PCR method. An embodiment relates to a novel fluorescence counting system for quantifying viruses or antibodies in an analyte which comprises an unit of providing an antigen or antibody phase solidified substrate by an aggregation method with quantum crystals, an unit for making a labeling liquor and labeling a virus or an antibody to be measured in the analyte by an antigen-antibody method, an unit of exciting the fluorescently labeled virus or antibody by a surface plasmon excitation method, and an unit of counting fluorescent points in an excited fluorescent screen to quantify the virus or antibody in the analyte. | 2021-11-04 |
20210341469 | COMPOSITIONS AND METHODS FOR PASSIVE OPTICAL BARCODING FOR MULTIPLEXED ASSAYS - Compositions comprising multiple hydrogel particles having substantially the same diameter, but with each subgrouping of particles from the multiple hydrogel particles having different associated values for one or more passive optical properties that can be deconvoluted using cytometric instrumentation. Each hydrogel particle from the multiple hydrogel particles can be functionalized with a different biochemical or chemical target from a set of targets. A method of preparing hydrogel particles includes forming droplets and polymerizing the droplets, with optional functionalization. | 2021-11-04 |
20210341470 | BIOMATERIAL-DETECTING MICROPARTICLE AND BIOMATERIAL DETECTION METHOD USING SAME - Microparticles for detecting biological materials are provided. Each of the microparticles includes: a core-shell structured microparticle consisting of a core including a magnetically responsive metal and a shell layer surrounding the core and having a uniform thickness; and capture probes introduced onto the shell layer to capture biological materials. | 2021-11-04 |
20210341471 | BIOSENSOR USING MAGNETIC NANOPARTICLES, AND DETECTION DEVICE AND DETECTION METHOD USING SAME - According to one embodiment of the present application, a biosensor, the biosensor comprising: a reaction part including a magnetic nanoparticle complex, a first electrode, and a second electrode; and a sample introduction part forming a passage so that a sample can be introduced into the reaction part from an outside of the biosensor; wherein the magnetic nanoparticle complex includes a first capturing substance for capturing a first target substance, a magnetic nanoparticle, and a reaction substance that performs at least one of an oxidation reaction and a reduction reaction, wherein the magnetic nanoparticle complex is magnetic in the reaction part, and has a property that mobility can be changed according to a change in a condition of the reaction part, wherein the first electrode, a second capturing substance for capturing a second target substance is fixed, wherein the second electrode is an electrode different from the first electrode, and characterized in that at least one of the first target substance and the second target substance is included in the sample, may be provided. | 2021-11-04 |
20210341472 | SOLID-PHASE SURFACE AND SOLUTION MOTION MODE AND MOTION DEVICE - The present disclosure provides modes of relative motion between a solid surface and a solution, and the related motion apparatuses. In an interaction between the solid surface and a target object, the target object is dissolved or dispersed in the solution, and the solid surface and the solution make a relative motion, with the relative motion including a relative movement perpendicular to the solid surface, in order to improve at least one of the following: binding rate, dissociation rate, binding uniformity, binding directionality and binding density of the target object to the solid surface. Compared with the traditional modes of relative motion in which the relative motion is parallel to a sensor surface, the modes of relative motion of the present disclosure can effectively improve the binding efficiency and dissociation efficiency between a ligand and an analyte given the same relative motion velocity between the sensor and the solution. | 2021-11-04 |
20210341473 | MOLECULAR WIRES FOR DETECTING A BIOLOGICAL OR CHEMICAL ENTITY OR EVENT - Enantiomeric pairs of molecular wires comprised of oligomeric nucleic acids, wherein the oligomers of each wire possess identical nucleobase pair sequences and thus identical conductivity as between wires, are constructed and used to sense biological or chemical entities of interest at the cellular or molecular level. The oligomeric molecular wires conduct voltage inputs to sensing subsystem integrated circuitry, either from an electrostatic potential arising from a targeting agent (i.e., a capture agent) binding to an intended biological or chemical target molecule, or from an electrostatic potential associated with a reference molecule that has non-specific interactions with the environment. The chirality of the oligomers imparts selectivity to either the targeting agent or the reference molecule during assembly of the sensing subsystem. | 2021-11-04 |
20210341474 | LIGHT MICROSCOPY CHIPS AND DATA ANALYSIS METHODOLOGY FOR QUANTITATIVE LOCALZIED SURFACE PLASMON RESONANCE (LSPR) BIOSENSING AND IMAGING - A method for the spatiotemporal mapping of receptor-ligand binding kinetics in localized surface plasmon resonance (LSPR) imaging using a chip for LSPR imaging having a glass coverslip compatible for use in a standard microscope and at least one array of functionalized plasmonic nanostructures patterned onto the glass coverslip with electron beam nanolithography and projecting a magnified image of the array to a CCD camera and monitoring the binding kinetics of the array. The nanostructures can be regenerated allowing the chip to be used multiple times. | 2021-11-04 |
20210341475 | ANTIBODY PAIRS FOR USE IN A RAPID INFLUENZA A DIAGNOSTIC TEST - Novel antibody pairs for use in an Influenza A diagnostic test. | 2021-11-04 |
20210341476 | VELVET DISEASE TEST AND METHOD - Velvet disease infestation is detected using rmAbs that are cross-reactive with one or more | 2021-11-04 |
20210341477 | Compositions, Methods, and Systems for Detecting Methicillin-Resistant Staphylococcus Aureus - Disclosed are compositions, methods and systems for detecting MRSA, for example MRSA nasal colonization. In certain embodiments, the methods use bacteriophage-based amplification of the signal in detection of bacteria and other microorganisms to detect MRSA. The methods for detecting MRSA may include preparing an assay comprising a selective agent and a cocktail comprising at least two different types of recombinant bacteriophages, incubating the sample in the assay, capturing an indicator protein product, and detecting an indicator protein product produced by the recombinant bacteriophage, wherein positive detection of the indicator protein product indicates that MRSA is present in the sample. | 2021-11-04 |
20210341478 | RECOMBINANT ANTIBODIES, KITS COMPRISING THE SAME, AND USES THEREOF - Disclosed herein is a recombinant antibody against the nucleocapsid protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A kit containing the recombinant antibody for use in coronavirus detection is encompassed in the present disclosure. Also disclosed herein are in vitro methods of detecting coronavirus infection in a subject with the aid of the recombinant antibody. | 2021-11-04 |
20210341479 | QUANTITATIVE ANTIBODY TEST - The present disclosure relates to methods and compositions, e.g., kits, for quantitatively detecting an antibody of a subject to an infectious organism. In some embodiments, the present disclosure provides for methods and compositions, e.g., kits, for quantitatively detecting a human antibody to SARS-CoV-2 polypeptide or S (spike) polypeptide. Certain applications and uses of the present methods and compositions, e.g., kits, are also provided. | 2021-11-04 |
20210341480 | VIRAL TESTING IN SALIVA - Saliva-based testing for viruses including SARS-CoV-2 are provided. Simple collection methods allow for at-home collection, reducing the risk and burden on healthcare workers using conventional testing methods. Tests can quantitatively analyze both viral nucleic acids to assess viral load as well as virus-specific antibodies to track disease progression and potential immunity. | 2021-11-04 |
20210341481 | METHODS FOR AIDING IN THE DIAGNOSIS AND DETERMINATION OF THE EXTENT OF TRAUMATIC BRAIN INJURY IN A HUMAN SUBJECT USING THE EARLY BIOMARKER UBIQUITIN CARBOXY-TERMINAL HYDROLASE L1 - Disclosed herein are methods that aid in the diagnosis and evaluation of a human subject that has sustained or may have sustained an injury to the head, such as mild or moderate to severe traumatic brain injury (TBI), using an early biomarker, ubiquitin carboxy-terminal hydrolase L1 (UCH-L1). Also disclosed here are methods that aid in determining whether a human subject that has sustained an injury or may have sustained to the head would benefit from and thus receive a head computerized tomography (CT) scan based on the levels of UCH-L1. These methods involve detecting levels and changes in levels of UCH-L1 in one or more samples taken from a human subject at time points within 24 hours after the subject has sustained or may have sustained an injury to the head. | 2021-11-04 |
20210341482 | CANCER BIOMARKERS - This invention relates to a method for determining if a cancer of a subject is expected to respond to chemotherapy. | 2021-11-04 |
20210341483 | SYSTEM AND METHOD FOR CLASSIFYING CANCER PATIENTS INTO APPROPRIATE CANCER TREATMENT GROUPS AND COMPOUNDS FOR TREATING THE PATIENT - A method for the prognosis of response to treatment for a patient suffering from cancer, the method comprising: measuring the expression of at least one immune marker in a leukocyte sample taken from the patient with cancer; classifying the patient sample into (i) sustainable responders (SR) to selective internal radiation therapy (SIRT) or (ii) transient/non-responders (TR/NR) to (SIRT) based on expression of the at least one immune marker in relation to a predetermined value and treating sustainable responders (SR) to SIRT or SIRT or a composition comprising SIRT and an immunotherapy. In a preferred embodiment, the method is for the prognosis of response to treatment of a Hepatocellular carcinoma (HCC) patient comprising detecting the co-expression of PD-1 or Tim-3 with CCR5; or expression of PD-1, Tim-3, CXCR6, or combinations thereof in a leukocyte sample taken from the patient. | 2021-11-04 |
20210341484 | Methods for Detecting Cancer-Related Cell Populations, Screening for Metastatic Cancer and Treatments Thereof - Provided are methods involving the assaying of a labeled cell suspension, e.g., to detect cancer-related cells, populations ON thereof and/or screen for metastatic cancer. Labeled cell suspensions may be assayed to detect whether a tumor infiltrating lymphocyte (TIL) population is present in a cellular suspension of a subject. Cancer-related cell populations of interest include, e.g., those expressing one or more markers, including where the markers are members of a marker panel. Markers assayed may vary depending on the context and may include protein markers, nucleic acid markers, cell cycle markers, DNA content markers, and the like. Useful markers include one or more immune checkpoint markers and/or one or more immune cell-type markers, including where the marker(s) assayed are part of one or more panels of markers. Also provided are methods of treating a subject for a neoplasia based on the outcome of an assay of a labeled cell suspension of sample from a subject. Kits for practicing the described methods are also provided. | 2021-11-04 |
20210341485 | Exosome Detection in Microfluidic Droplets - A platform technology for the detection and quantification of biomarkers in exosomes secreted by single cells uses a microfluidic system and provides methods of diagnosis and prognosis of cancer and other conditions using the biomarkers. Single cells can be obtained from a subject and characterized by their exosome population. The biomarkers can be detected at extremely low levels using rolling circle amplification and multiplex analysis to enhance specificity and sensitivity of the analysis. | 2021-11-04 |
20210341486 | METHODS AND KITS FOR PREDICTING PROGNOSIS OF CANCER USING SOLUBLE MORTALIN IN BLOOD - Provided are methods of determining a presence or level of soluble mortalin in a body fluid of a subject, and predicting prognosis of a subject diagnosed with cancer (e.g., solid tumor) by determining the presence or level of soluble mortalin in a body fluid of the subject. Also provided are kits for determining presence and/or level of soluble mortalin in a body fluid of the subject and/or predicting prognosis of a subject diagnosed with cancer, comprising at least two distinct antibodies to mortalin directed against different epitopes of said mortalin. | 2021-11-04 |
20210341487 | NEUTRALIZING ANTIBODY ASSAY FOR THERAPEUTIC PROTEINS - The present invention generally pertains to methods of testing for the presence of neutralizing antibodies (NAbs) against therapeutic proteins. In particular, the present invention pertains to the use of mitigating agents against interfering competing drugs in ligand binding assays or cell-based assays for the detection of neutralizing antibodies against therapeutic proteins. | 2021-11-04 |
20210341488 | FLUORESCENCE POLARIZATION IMMUNOASSAY AND FLUORESCENT LABELING SUBSTANCE - A fluorescence polarization immunoassay that uses a fluorescent labeling substance in which a single domain antibody is labeled with a fluorescent dye. A fluorescent labeling substance obtained by labeling a single domain antibody, such as a VHH antibody or a vNAR antibody, having a binding ability to a target substance with a fluorescent dye is used. The fluorescence polarization immunoassay includes a binding step for binding the fluorescent labeling substance to a target substance; and a measuring step for measuring a change in the fluorescence polarization of the fluorescent labeling substance to which the target substance is bound. | 2021-11-04 |
20210341489 | METHOD AND COMPOSITION FOR DETERMINING SPECIFIC ANTIBODY RESPONSES TO SPECIES OF FILOVIRUS - The disclosure relates to compositions, assays, methods and kits comprising one or more amino acid sequences of a filovirus protein, or a fragment thereof, which find use in the detection of a filovirus infection and/or the presence of antibodies specific for a filovirus in a biological sample. | 2021-11-04 |
20210341490 | METHODS FOR DETECTING AND/OR MEASURING ANTI-DRUG ANTIBODIES, IN PARTICULAR TREATMENT-EMERGENT ANTI-DRUG ANTIBODIES - Described herein are methods, assays and techniques for detecting and/or measuring anti-drug antibodies that bind to a protein, polypeptide or other compound or molecule that comprises at least one immunoglobulin variable domain with an exposed C-terminal region. | 2021-11-04 |
20210341491 | Rheumatoid arthritis auto-antibody-bound peptide and application thereof - The present invention relates to a peptide capable of binding to rheumatoid arthritis autoantibodies, which is a consecutive 10-25 amino acid sequence of any one fragment of the group consisting of SEQ ID NO: 3-4, 7-13 or 16-19, wherein the peptide fragment has an epitope that binds to the rheumatoid arthritis autoantibodies. Furthermore, the peptide fragment bound to the rheumatoid arthritis autoantibodies is used for testing rheumatoid arthritis, and according to this use, the present invention provides a method for testing rheumatoid arthritis disease and a test reagent kit used for determining whether a subject to be tested suffers from rheumatoid arthritis disease. | 2021-11-04 |
20210341492 | NEWBORN SCREENING FOR PRIMARY IMMUNODEFICIENCIES, CYSTINOSIS, AND WILSON DISEASE - Newborn screening for primary immunodeficiencies, cystinosis, and Wilson disease is described. The newborn screening can detect these disorders from dried blood spots already routinely collected at the time of birth. Early detection of these disorders will greatly improve patient outcome as each of them can be fatal once symptoms emerge. | 2021-11-04 |
20210341493 | tTG-DGP BIOMARKERS FOR MONITORING CELIAC DISEASE - The present disclosure relates generally to biomarkers and peptide arrays, and, more particularly, to a method of using a peptide array to identify biomarkers for an autoimmune disease such as, e.g., Celiac disease. Furthermore, a set of novel biomarkers for Celiac disease, having high sensitivity and specificity, are disclosed in addition to method of treatment using the novel biomarkers. | 2021-11-04 |
20210341494 | Personalized Medicine Approach for Treating Cognitive Loss - The present invention includes methods for selecting a therapy for improved cognition as well as prevention of cognitive loss/dysfunction using one or more endophenotypes comprising: obtaining a sample from a subject; measuring biomarkers that differentiate between an inflammatory, a metabolic, a neurotrophic, and a depressive endophenotype; and selecting a course of treatment for the subject based on whether the subject is scored as having a high or a low endophenotype for one or more of the inflammatory, a metabolic, a neurotrophic, and a depressive endophenotypes. | 2021-11-04 |
20210341495 | METHODS OF TREATING BASED ON SITE-SPECIFIC TAU PHOSPHORYLATION - The present disclosure provides methods to quantify tau phosphorylation at specific amino acid residues to predict time to onset of mild cognitive impairment due to Alzheimer's disease, stage Alzheimer's disease, guide treatment decisions, select subjects for clinical trials, and evaluate the clinical efficacy of certain therapeutic interventions. | 2021-11-04 |
20210341496 | Systems and Methods for Detecting or Monitoring Insulin - Methods and systems for insulin detection. The methods may include contacting one or more islets with glucose to produce a first stream that is then contacted with an anti-insulin antibody and a labeled insulin to produce a second stream. The second stream may be analyzed to determine a ratio of antibody-bound (B) labeled insulin to free (F) labeled insulin in the second stream, wherein the ratio of B:F is inversely related to a concentration of target insulin. | 2021-11-04 |
20210341497 | DIAGNOSIS METHOD FOR DISEASES ACCOMPANIED BY REDUCED BONE DENSITY - The invention relates to a method for diagnosing a disease that is accompanied by reduced bone density and/or calcium loss, comprising the following steps: a) determining isotope ratios or amount ratios of alkaline-earth metal portions in a sample of urine or blood or stool, b) thereby determining at least one sample value, and c) comparing the at least one sample value with a threshold value, the threshold value being selected independently of one or more factors determined by the individual patient. The invention further relates to a test kit for use in carrying out the method. | 2021-11-04 |
20210341498 | BLOOD-CLOTTING-SYSTEM ANALYSIS APPARATUS, BLOOD-CLOTTING-SYSTEM ANALYSIS METHOD, AND BLOOD-CLOTTING-SYSTEM ANALYSIS PROGRAM - There is provided a blood-clotting-system analysis apparatus, including: a pair of electrodes; an application unit configured to apply alternating voltage to the pair of electrodes at predetermined time intervals; a measurement unit configured to measure a complex dielectric constant of a blood sample placed between the pair of electrodes; and an analysis unit configured to analyze, by using at least two or more types of blood clotting-related assays, activity of a clotting factor and activity of a clotting inhibition factor on a basis of a complex dielectric constant of a particular frequency in a predetermined time period measured at the time intervals after an anticoagulant effect acting on the blood sample is resolved. | 2021-11-04 |
20210341499 | CARTRIDGE DEVICE FOR A MEASURING SYSTEM FOR MEASURING VISCOELASTIC CHARACTERISTICS OF A SAMPLE LIQUID, A CORRESPONDING MEASURING SYSTEM, AND A CORRESPONDING METHOD - The present invention is directed to a cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, in particular a blood sample, comprising a cartridge body having at least one measurement cavity formed therein and having at least one probe element arranged in said at least one measurement cavity for performing a test on said sample liquid; and a cover being attachable on said cartridge body; wherein said cover covers at least partially said at least one measurement cavity and forms a retaining element for retaining said probe element in a predetermined position within said at least one measurement cavity. The invention is directed to a measurement system and a method for measuring viscoelastic characteristics of a sample liquid. | 2021-11-04 |
20210341500 | FLUID HANDLING APPARATUS AND CONFIGURATIONS - Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample. | 2021-11-04 |
20210341501 | AUTOMATIC ANALYZING APPARATUS - According to one embodiment, an automatic analyzing apparatus includes a dispenser, a rod, and control circuitry. The dispenser supplies at least one of a reagent and a specimen. The rod adheres at least one of the reagent and the specimen supplied from the dispenser. The control circuitry inserts the rod to which said at least one of the reagent and the specimen is adhered into a liquid contained in a vessel. | 2021-11-04 |
20210341502 | ABNORMALITY DETERMINING METHOD, AND AUTOMATIC ANALYZER - Provided are an improved abnormality determining method for an automatic analyzer and related automatic analyzer which includes an abnormality determining method for a reaction process of a reaction solution. The abnormality determining method includes: acquisition by a processor of acquisition conditions that include information relating to a number of divisions of a measured value range and information relating to the number of items of data in each divided segment for a plurality of items of measured data; acquisition, of a plurality of items of measured data that are detected using a spectral detector and that match the acquisition conditions; calculation of a feature quantity of the data; generation of the determination criterion on the basis of the feature quantity of the data; and determination of abnormalities by means of a comparison between the feature quantity of the subject data and the determination criterion. | 2021-11-04 |
20210341503 | AUTOMATIC ANALYZER AND MAINTENANCE SUPPORT METHOD - Provided is an automatic analyzer in which user work is in conjunction with apparatus driving and operation of a user even in complicated maintenance work is simplified. The automatic analyzer includes a measurement device | 2021-11-04 |
20210341504 | VISUALIZATION ANALYSIS APPARATUS AND VISUAL LEARNING METHODS - A method of characterizing a specimen in a specimen container includes capturing one or more images of the specimen container, wherein the one or more images include one or more objects of the specimen container, and wherein the capturing generates pixel data from a plurality of pixels. The method further includes identifying one or more selected objects from the one or more objects, displaying an image of the specimen container, and displaying, on the image of the specimen container, one or more locations of pixels used to identify the one or more selected objects. Other apparatus and methods are disclosed. | 2021-11-04 |
20210341505 | LABORATORY CONTAINER STORAGE SYSTEM - The present disclosure relates to a laboratory container storage system, a laboratory system comprising the laboratory container storage system, and a method of operating the laboratory system. The laboratory container storage system comprising one or more laboratory container storage devices. Each laboratory container storage device comprises a frame and a storage element comprising a holder configured to receive and release a laboratory container horizontally and to hold the laboratory container in a suspended position above a horizontal surface. The storage element is mounted movably on the frame and configured to be moved between a first transfer position and a storage position and between the storage position and a second transfer position. In the first and second transfer position, the holder is positioned to receive or release the laboratory container horizontally. The storage position is located between the first and second transfer position. | 2021-11-04 |
20210341506 | AUTOMATIC ANALYZER - Dispensing with liquid dropping from a tip end of a dispensing probe and/or droplets attaching on the tip end when exchanging the probe allows providing an automatic analyzer excellent in maintenance and reliability. The automatic analyzer includes a probe | 2021-11-04 |
20210341507 | SENSOR APPARATUS, INFORMATION PROCESSING APPARATUS, METHOD OF OUTPUTTING MEASUREMENT DATA WITH SETTINGS, INFORMATION PROCESSING METHOD, PROGRAM, AND DATA STRUCTURE OF MEASUREMENT DATA WITH SETTINGS - A measurement data acquisition section acquires the measurement data indicating at least one from among the position, the orientation, the velocity, the acceleration, the angular velocity, and the angular acceleration measured by the sensor. A measurement-data-with-settings generation section generates measurement data with settings including the measurement data and coordinate system setting data indicating settings for a coordinate system used for expressing at least one from among the position, the orientation, the velocity, the acceleration, the angular velocity, and the angular acceleration indicated by the measurement data. A measurement-data-with-settings output section outputs the measurement data with settings. | 2021-11-04 |
20210341508 | ACTIVITY TRACKING USING MOTION SENSORS IN A WIRELESS LUMINAIRE NETWORK - An example method includes determining, at an aggregated point in time, an aggregated space node motion amount detected in a plurality of node sensing areas of a plurality of the nodes. The determining the aggregated space node motion amount includes compiling a plurality of sensing records from a subset or all of the nodes created by the subset or all of the nodes at a time substantially close to the aggregated point in time. The method additionally includes computing a temporal aggregated motion amount detected in a node sensing area of a respective node over time, using the aggregated time node motion amount. The method further includes computing a spatial aggregated motion amount in a portion of a space, using the aggregated space node motion amount, wherein the portion of the space correlates to the node sensing areas of the plurality of nodes. | 2021-11-04 |
20210341509 | ATTACHABLE WIND DETECTION DEVICE - A wind detection device with a flexible enclosure, and opening, and a dispensing tube, filled with powder or liquid and designed to be attached to hunting equipment, headgear, or clothing, wherein pressing on the outside of the device causes a puff of powder or vapor to be dispensed into the air, allowing the user to determine wind direction. | 2021-11-04 |
20210341510 | MICROMECHANICAL SENSOR SYSTEM, METHOD FOR USING A MICROMECHANICAL SENSOR SYSTEM - A micromechanical sensor system, in particular, an acceleration sensor, including a substrate having a main extension plane, the sensor system including a first mass and a second mass. The first and second masses are each designed to be at least partially movable in a vertical direction, perpendicular to the main extension plane of the substrate. The first mass includes a stop structure, wherein the stop structure has an overlap with the second mass in the vertical direction. | 2021-11-04 |
20210341511 | Physical Quantity Sensor, Composite Sensor, Inertial Measurement Unit, Portable Electronic Apparatus, Electronic Apparatus, And Vehicle - A gyro sensor includes: a spring having an inner span beam connected to an outer span beam via a turnaround beam; and a fixed driver that laterally faces the outer beam. A first beam is provided to the structure side of the outer beam so as to face the outer beam. T | 2021-11-04 |
20210341512 | SYSTEM AND METHOD FOR DETERMINING WHETHER AN ELECTRONIC DEVICE IS LOCATED ON A STATIONARY OR STABLE SURFACE - An embodiment system includes: a first motion sensor configured to generate first sensor data indicative of a first type of movement of an electronic device; a first feature detection circuit configured to determine at least one orientation-independent feature based on the first sensor data; and a classifying circuit configured to determine whether or not the electronic device is located on a stationary surface based on the at least one orientation-independent feature. | 2021-11-04 |
20210341513 | High Speed Atomic Force Profilometry of Large Areas - An apparatus and method of operating an atomic force profiler (AFP), such as an AFM, using a feedforward control signal in subsequent scan lines of a large area sample to achieve large throughput advantages in, for example, automated applications. | 2021-11-04 |
20210341514 | TESTING DEVICE WITH POWER PROTECTION AND ITS TESTING PLATFORM - A testing device with power protection includes a power interface and a testing platform. The testing platform includes a casing, a fixed frame and a sliding frame. The power interface is disposed at one surface of the casing. The fixed frame covers the power interface. One side of the fixed frame formed with an entrance that exposes the power interface outwards from the fixed frame. The sliding frame includes a rack body slidably that is located on the casing, and a shielding door that is rotatably connected to the rack body for covering the entrance of the fixed frame. When the rack body is slid towards the power interface so as to rotate the shielding door away from the entrance by the fixed frame, the power interface is exposed outwards from the fixed frame through the entrance. | 2021-11-04 |
20210341515 | INTERMEDIATE CONNECTING MEMBER AND INSPECTION APPARATUS - An intermediate connecting member according to one aspect of the present disclosure is provided between a first member including multiple first terminals and a second member including multiple second terminals. The intermediate connecting member includes multiple connection parts configured to electrically connect the first terminals to the second terminals, and a retainer holding the multiple connection parts. Each of the multiple connection parts is formed of an elastic member to which an electrically conductive property is given at least on a surface of the elastic member. | 2021-11-04 |
20210341516 | PROBE PIN AND INSPECTION MODULE - A probe pin includes: a reference axis extending along a longitudinal direction of the probe pin; a head portion, which includes, in a sequential order along the reference axis, a sensing end, at least one positioning recess, and a first spring engaging portion; a bottom portion, including a connecting end; and a spring, disposed between the top and bottom portions, wherein the spring encircles and engages with the first spring engaging portion, and abuts the bottom portion. | 2021-11-04 |
20210341517 | MEASUREMENT SYSTEM AND METHOD FOR OPERATING A MEASUREMENT SYSTEM - A measurement system is described. The measurement system comprises a measurement device and a probe unit, wherein the measurement device comprises an image analysis circuit or module. The probe unit comprises at least one image sensor, wherein the at least one image sensor is connected to the image analysis module in a signal transmitting manner. The image sensor is configured to capture an image of a measurement area being associated with a device under test. The image analysis module is configured to analyze the image captured and to determine at least one characteristic quantity of the image captured via an image analysis technique. The image analysis module is further configured to gather an information concerning a test position of the probe unit from the at least one characteristic quantity. Further, a method for operating a measurement system is described. | 2021-11-04 |