44th week of 2008 patent applcation highlights part 54 |
Patent application number | Title | Published |
20080269043 | Ceramic Insulating Material and Sensor Element Containing a Ceramic Insulating Material - A ceramic insulating material, in particular for sensor elements for determining the concentration of gas components in gas mixtures, is based on an alkaline earth-containing ceramic. The insulating material contains a hexaaluminate of the alkaline earth metal and at least one mixed compound of the alkaline earth metal with an acid oxide, the molar ratio of hexaaluminate to the sum of mixed compounds in the insulating material being 1.3 to 4.0. | 2008-10-30 |
20080269044 | Chalcogenide glass composition - A chalcogenide glass composition composed of arsenic (As), selenium (Se), sulfur (S), and antimony (Sb) is presented. The composition includes arsenic in the range from 25% to 45% by weight relative to the total weight of the composition, selenium in the range from 40% to 65% by weight relative to the total weight of the composition, sulfur in the range from 2% to 15% by weight relative to the total weight of the composition, and antimony in the range from 0% to 15% by weight relative to the total weight of the composition. The variability of constituents on a weight basis is greater than the related arts, thus facilitating a broader range of design options. The glass composition is preferred to have a thermal expansion coefficient of about 23.6×10 | 2008-10-30 |
20080269045 | PRODUCTION OF LOWER MOLECULAR WEIGHT HYDROCARBONS - A catalytic composition useful for cracking and reducing the viscosity of heavy hydrocarbons. The catalytic composition comprises Portland cement, a volcanic ash component, titanium dioxide, and a transition metal salt. Optionally, a hydrogen source is added to the catalytic composition. | 2008-10-30 |
20080269046 | EXHAUST GAS PURIFICATION CATALYST AND MANUFACTURING METHOD THEREOF - In an exhaust gas purification catalyst that contains an oxygen storage component containing Ce and Zr, alumina and a catalytic metal, a plurality of primary particles of the oxygen storage component and a plurality of primary particles of the alumina agglomerate to form each of mixed oxide particles and the catalytic metal includes Pd doped in the oxygen storage component particles to constitute each of the oxygen storage component particles with Ce and Zr and exposed at the surfaces of the oxygen storage component particles and Pd adhered to the surfaces of the oxygen storage component particles and the surfaces of the alumina particles. | 2008-10-30 |
20080269047 | Method for Producing Thermosensitive Recording Material and Recording Material Produced According to Said Method - The invention relates to a method for producing thermosensitive recording material, comprising a carrier substrate and a thermal reaction layer containing a colour former and a colour developer. According to the invention, an application suspension, containing the starting materials of the thermal reaction layer, is applied to the carrier substrate and the carrier substrate is subsequently dried with the applied application suspension. Then the dried carrier substrate with the applied thermal reaction layer is guided through a smoothing mechanism in order to be smoothed, wherein the dried carrier substrate with the applied thermal reaction layer is pressed extensively against a roller by means of a predetermined contact pressure. The invention also relates to a recording material which is produced according to the inventive method. | 2008-10-30 |
20080269048 | CARDBOARD CYLINDER FOR A HEAT-SENSITIVE TRANSFER IMAGE-RECEIVING SHEET, ROLLED HEAT-SENSITIVE TRANSFER IMAGE-RECEIVING SHEET TO FORM A ROLL SHAPE, AND IMAGE-FORMING METHOD - A cardboard cylinder for winding a heat-sensitive transfer image-receiving sheet having a receptive layer on one surface of a support around the cardboard cylinder, wherein an innermost surface of the cardboard cylinder is composed of a layer containing a polyolefin resin having a number average molecular weight of 12,000 or more in a proportion of at least 80% by mass based on the layer. | 2008-10-30 |
20080269049 | Color forming compositions with a fluoran leuco dye having a latent developer - Compositions and systems for production of color images with a fluoran leuco dye having a latent developer are disclosed and described. A color forming composition or composite can include a polymer matrix, a thermally modifiable fluoran leuco dye having a latent developer attached thereto, and a radiation absorber. The thermally modifiable fluoran leuco dye can be developable upon the color forming composition being contacted with electromagnetic radiation which causes the radiation absorber to become energized, so that the energized radiation absorber causes the latent developer to undergo rearrangement to produce an intermediate dye form having a phenolic substituent. The intermediate dye can then undergo an acid catalyzed ring opening to produce a colored dye form. | 2008-10-30 |
20080269050 | Time/Temperature Indicators - By printing a bar code (comprising dark and light regions) or parts of such a bar code with an ink containing a dye, which changes colour in the presence of an acid or a base to remove the contrast between the regions of the bar code, and a neutral compound which releases an acid or a base on exposure to energising radiation, a bar code can be produced that becomes unreadable after a pre-determined interval. This can be used as a time/temperature indicator to ensure that products, which might be perishable, associated with such a bar code are not used by the public. | 2008-10-30 |
20080269051 | Fungicidal Active Compound Combinations - The invention relates to active compound combinations comprising firstly the known fluoxastrobin and secondly further known fungicidal active compounds, which combinations are highly suitable for controlling unwanted phytopathogenic fungi. | 2008-10-30 |
20080269052 | USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS - According to the invention, compounds of the general formula (I) or salts thereof (pyridine-2-oxy-3-carboxamides), | 2008-10-30 |
20080269053 | Amino Acid Compositions and Methods of Using as Fertilizer - Compositions including an amino acid product, and uses thereof as fertilizers are disclosed. | 2008-10-30 |
20080269054 | Preparation Containing Uv Radiation Absorbing Metal Oxide Powder and a Superspreading Agent - Preparation containing at least one UV radiation absorbing metal oxide powder and at least one superspreading agent. Use of the preparation for the reduction of sunburn damage in useful plants. | 2008-10-30 |
20080269055 | Plant Growth Regulation - The present invention relates to a new class of plant growth regulators. In particular, the invention relates to fused azepinone derivative of general formula (I) or an agriculturally acceptable salt thereof wherein X is CO | 2008-10-30 |
20080269056 | Defoliant - A mixture, which comprises
| 2008-10-30 |
20080269057 | Grape Sugar Development - Grape sugar development is improved by applying to the vine or to the locus of the vine a composition comprising an iron chelate. Advantages include increasing the overall sugar content of grapes and increasing the rate of development the sugar. A preferred iron chelate is the iron chelate of EDDHA, available commercially as SEQUESTRENE 138 Fe 100. | 2008-10-30 |
20080269058 | Methods of Altering Poppy Characteristics - The present invention relates to the use of sulfonylurea compounds to alter physical and/or growth characteristics of poppy plants. | 2008-10-30 |
20080269059 | PYRIDINECARBOXAMIDES, USEFUL-PLANT-PROTECTING COMPOSITION COMPRISING THEM AND PROCESSES FOR THEIR PREPARTION AND THEIR USE - Compounds of the formula (I), or salts thereof, | 2008-10-30 |
20080269060 | Herbicidal Formulation - An aqueous pre-mix suspension concentrate formulation comprising: (i) water, (ii) an HPPD inhibitor, in suspension in the water, and (iii) an electrolyte, in solution in the water which has improved stability of the HPPD inhibitor is disclosed. | 2008-10-30 |
20080269061 | Substituted thiene-3-ylsulphonylamino(thio)carbonyltriazolin(ethi)ones - The invention relates to novel substituted thiene-3-ylsulphonylamino(thio)carbonyl-triazolin(ethi)ones of the general formula (I) | 2008-10-30 |
20080269062 | BANDPASS FILTER AND FORMING METHOD OF THE SAME - A bandpass filter capable of creating a dual mode with a simple configuration and stably adjusting the filter characteristics of the bandpass filter is disclosed. The bandpass filter includes a dielectric base substrate; a disk resonator formed over the dielectric base substrate; and a dielectric block disposed over a part of the dielectric base substrate and in substantially the same plane as the disk resonator. | 2008-10-30 |
20080269063 | METHOD AND SYSTEM FOR PREPARING A MICROARRAY FOR A DISEASE ASSOCIATION GENE TRANSCRIPT TEST - System and method for preparing a microarray for a disease association gene transcript test. Disease considerations for this unique test include a custom set of genetic sequences associated in peer-reviewed literature with various known diseases such as Addison's disease, anemia, asthma, atherosclerosis, autism, breast cancer, estrogen metabolism, Grave's disease, hormone replacement therapy, major histocompatibility complex (MHC) genes, longevity, lupus, multiple sclerosis, obesity, osteoarthritis, prostate cancer, and type 2 diabetes. The base dataset may be developed through clinical samples obtained by third-parties. Online access of real-time phenotype/genotype associative testing for physicians and patients may be promoted through an analysis of a customized microarray testing service. | 2008-10-30 |
20080269064 | Method and Kit for Detecting Components in a Sample - Methods and a kit for use in the detection of a component in a sample on a solid support are disclosed which use a conjugate and polymer having metal particles of diameter in the nanometer range (that is between 0.1 and 500 nm). Methods and a kit for detection of a component in a sample on a solid support which have a conjugate and optionally a polymer bound to one or more supermagnetic particles are also disclosed. The methods and kits may be used for enhancing in vivo imaging and microscopy. | 2008-10-30 |
20080269065 | Conformationally Constrained Analytical Probes - There is disclosed probes bearing partial metal chelators that in some embodiments are conformationally constrained. In certain embodiments such probes are useful in methods for the detection of a specific target molecule. These target molecules may include oligonucleotides, peptides, proteins, polysaccharides, or small molecules. There is further disclosed the use of probes with partial metal chelators engaged in a coordination complex with one another that imposes a structural constraint in the probe and increases the specificity factor of the probe. | 2008-10-30 |
20080269066 | Method and Array for the Replication and Analysis of Nucleic Acids - The invention includes a method and array for replicating and analyzing one or a plurality of different target sequences in nucleic acid samples. The different reactions for replicating the target sequences occur simultaneously on an array with selectively heatable array elements with their reaction surfaces, some of which have been modified differently, and in the sample solution disposed thereabove. The target sequences are analyzed using molecular detection on reaction surfaces of said array that have been modified with probe strands. The target strands are replicated and analyzed simultaneously, successively, or alternately. | 2008-10-30 |
20080269067 | Companion diagnostic assays for cancer therapy - A method for classifying cancer patients as eligible to receive cancer therapy comprising determination of the presence or absence in a patient tissue sample of chromosomal copy number gain at chromosomal locus 18q21-q22. The classification of cancer patients based upon the presence or absence of 18q21-q22 gain allows selection of patients to receive chemotherapy, such as therapy with a Bcl-2 family inhibitor, and for monitoring patient response to therapy. | 2008-10-30 |
20080269068 | MULTIPLEX DECODING OF SEQUENCE TAGS IN BARCODES - Methods and compositions for performing multiplex reactions are provided. | 2008-10-30 |
20080269069 | Method of Performing a Microarray Assay - Disclosed is a method for performing a microarray assay on one or more sample fluid(s), said fluids comprising target biological compounds. The method comprises the step of tagging said target biological compounds with labels. The following step comprises contacting said sample fluid(s) with a substrate and detecting the presence of said labels at the surface of said substrate. The method is suitable for the simultaneous analysis, in one microarray, of one or more types of target biological compounds, in one or more sample fluid(s). To this end each of said types of biological compounds is tagged with a different label so that target biological compounds belonging to different sample fluids have different labels. Said different labels are discriminable upon detection at the surface of said substrate. Also disclosed is the use of a polymer substrate in a method for performing a microarray assay. | 2008-10-30 |
20080269070 | METHOD FOR RAPIDLY SCREENING MICROBIAL HOSTS TO IDENTIFY CERTAIN STRAINS WITH IMPROVED YIELD AND/OR QUALITY IN THE EXPRESSION OF HETEROLOGOUS PROTEINS - The present invention provides an array for rapidly identifying a host cell population capable of producing heterologous protein with improved yield and/or quality. The array comprises one or more host cell populations that have been genetically modified to increase the expression of one or more target genes involved in protein production, decrease the expression of one or more target genes involved in protein degradation, or both. One or more of the strains in the array may express the heterologous protein of interest in a periplasm compartment, or may secrete the heterologous protein extracellularly through an outer cell wall. The strain arrays are useful for screening for improved expression of any protein of interest, including therapeutic proteins, hormones, a growth factors, extracellular receptors or ligands, proteases, kinases, blood proteins, chemokines, cytokines, antibodies and the like. | 2008-10-30 |
20080269071 | PSEUDOPTEROSIN-PRODUCING BACTERIA AND METHODS OF USE - Clonal strains of bacteria derived from | 2008-10-30 |
20080269072 | Rational Probe Optimization for Detection of MicroRNAs - A method for the rational optimization of probes for the detection of miRNAs from different species is provided. | 2008-10-30 |
20080269073 | DIRECT WRITE NANOLITHOGRAPHIC DEPOSITION OF NUCLEIC ACIDS FROM NANOSCOPIC TIPS - The use of direct-write nanolithography to generate anchored, nanoscale patterns of nucleic acid on different substrates is described, including electrically conductive and insulating substrates. Modification of nucleic acid, including oligonucleotides, with reactive groups such as thiol groups provides for patterning with use of appropriate scanning probe microscopic tips under appropriate conditions. The reactive groups provide for chemisorption or covalent bonding to the substrate surface. The resulting nucleic acid features, which exhibit good stability, can be hybridized with complementary nucleic acids and probed accordingly with use of, for example, nanoparticles functionalized with nucleic acids. Patterning can be controlled by selection of tip treatment, relative humidity, and nucleic acid structure. | 2008-10-30 |
20080269074 | Methods, Kits and Compositions Pertaining to Combination Oligomers and Libraries for Their Preparation - This invention pertains to the field of combination oligomers, including the block synthesis of combination oligomers in the absence of a template, as well as related methods, kits, libraries and other compositions. | 2008-10-30 |
20080269075 | Method and Device to Optimize Analyte and Antibody Substrate Binding by Least Energy Adsorption - The present invention provides a method of making an assay device for conducting an assay to detect a concentration of an analyte in a sample fluid. The assay devices would typically have a substantially planar surface having a series of site specific immobilized calibration spot arrays containing pre-determined quantities of the analyte printed thereon. In addition, a series of site specific immobilized test spot arrays, including capture antibody for binding the analyte protein is printed on the assay device. The method involves first modifying the planar surface to provide hydrophobic binding sites, hydrophilic linking and covalent bonding sites. Then the method requires printing the series of site specific immobilized test spot arrays and the series of site specific immobilized calibration spot arrays on the substantially planar surface. Applying the sample fluid to the assay device is the next step followed by testing a sensitivity of the assay and modulating ratios of the hydrophobic, hydrophilic and covalent binding sites in order to optimize the sensitivity of the assay. | 2008-10-30 |
20080269076 | Multiple Capillary Device and Method for Synthesis and Dispensing - A system and method for synthesizing a peptide, a nucleic acid sequence, an oligonucleotide, a DNA sequence, an RNA sequence, or the like, inside an array of capillary tubes, is provided. The system can comprise an array of capillary tubes. Each of the capillary tubes in the array of capillary tubes can comprise a first end, a second end, an inner wall, and a sequence linker bonded to the inner wall. The system can comprise a pressure control source that can be in fluid communication with each of the first ends of the array of capillary tubes. The system can comprise a reagent container support, wherein the second end of each of the capillary tubes can be adapted to move towards and/or away from the reagent container support. | 2008-10-30 |
20080269077 | CENTRIFUGAL MICROFLUIDIC DEVICE HAVING SAMPLE DISTRIBUTION STRUCTURE AND CENTRIFUGAL MICROFLUIDIC SYSTEM INCLUDING THE CENTRIFUGAL MICROFLUIDIC DEVICE - Provided are a centrifugal microfluidic device having a sample distribution structure and a centrifugal microfluidic system including the centrifugal microfluidic device. The centrifugal microfluidic device includes: a rotatable platform; a sample chamber which is disposed in the rotatable platform and houses a fluid sample; a distribution channel connected to an outlet of the sample chamber; a valve which is disposed in the outlet of the sample chamber; a plurality of non-vented reaction chambers which are disposed in the rotatable platform outside of the distribution channel in the radial direction; and a plurality of inlet channels connecting the distribution channel with the reaction chambers. | 2008-10-30 |
20080269078 | Nanoscale array biomolecular bond enhancer device - The invention teaches the use of an addressable nanoscale device to create a programmable substrate useful in selectively attracting proteins, nucleating protein crystals and growing protein crystals of a size amenable to diffraction analysis. Further taught is the use of nanoscale assemblies to create charge patterns, where such charge patterns are useful in purifying, nucleating or crystallizing protein molecules. Charge extension moieties, including water, are taught. The invention provides rapid and efficient identification, purification and detection of proteins and protein-related complexes. | 2008-10-30 |
20080269079 | Polymer Coated Bridging Solids and Weighting Agents for Use in Drilling Fluids - A wellbore fluid having at least two phases, including a fluid phase and a solid phase. The solid phase is a powdered solid material coated with a polymer that is the reaction product of a polyether amine and a dialdehyde crosslinking agent. Preferably the polyether amine is a diamine and more preferably the compound acts as a shale hydration inhibitor. The dialdehyde crosslinking agent reacts with the polyether amine compound and forms the polymeric material coating the solid. The polymer is substantially solubilized when the pH of the fluid has a value of less than about 7. | 2008-10-30 |
20080269080 | Wellbore Treatment Compositions Containing Foam Extenders and Methods of Use Thereof - This invention relates to fluid compositions used in treating a subterranean formation. In particular, the invention is aqueous wellbore treatment compositions which are foams containing a viscosifying agent, a foam extender, a gas component, and a surfactant, as well as methods of forming such fluids, and uses thereof. The viscosifying agent may be a hydratable polymer, viscoelastic surfactant, or heteropolysaccharide. The foam extender may be a material such as a polyoxyalkyleneamines, ethylenepolyamines, tertiary polyamines, bicarbonate, carbonate, phosphate, or sesquicarbonate. | 2008-10-30 |
20080269081 | Internal Breakers for Viscoelastic Surfactant Fluids - Internal breakers are given that break fluids viscosified with non-polymeric viscosifiers such as viscoelastic surfactants, inside formation pores. The breakers are polyols, for example natural and synthetic sugars, monoalcohols, and mixtures of the two. The sugars may be ketones and aldehydes. The sugars are also breaker aides for oxidizing agents used as breakers. Methods of using the breakers and breaker aides in oilfield treatment fluids are given. | 2008-10-30 |
20080269082 | DELAYED HYDROCARBON GEL CROSSLINKERS AND METHODS FOR MAKING AND USING SAME - A cross-link delaying or retarding composition, a cross-linking system including the cross-link delaying or retarding composition, or a fracturing fluid including a cross-linking system and a cross-link delaying or retarding composition are disclosed along with methods for making and using the compositions. | 2008-10-30 |
20080269083 | Oil Reservoir Treatment Method By Injection of Nanoparticles Containing an Anti-Mineral Deposit Additive - The invention relates to a method of treating permeable rocks wherein the following stages are carried out: producing particles of nanometric size comprising an active anti-mineral-deposit water-soluble polymer encapsulated in either a matrix so as to form a nanocomplex or a nanosphere, or in a membrane so as to form a nanocapsule; maintaining an amount of said particles dispersed in a liquid phase; injecting the dispersion into the permeable rock; and releasing the active polymer upon contact with salt water. | 2008-10-30 |
20080269084 | HEAT DISSIPATING SILICONE GREASE COMPOSITIONS - A silicone grease composition comprising 3-30 wt % of an organopolysiloxane and 60-96.9 wt % of a heat conductive filler is diluted with a least volatile isoparaffin having a boiling point of 260-360° C. Despite a heavy loading of heat conductive filler, the grease composition is easily applicable to heat sinks as a thin uniform coating. The composition is drastically increased in shelf stability at room temperature, easy to handle, and provides for good heat dissipation. | 2008-10-30 |
20080269085 | LUBRICATING OIL COMPOSITION CONTAINING ALKALI METAL BORATES WITH IMPROVED FRICTIONAL PROPERTIES - A lubricating oil composition with improved frictional and wear performance, especially when the ratio of polysulfides is controlled, wherein said composition comprises a major amount of an oil of lubricating viscosity, at least one alkali metal borate; at least one dihydrocarbyl polysulfide component comprising a mixture of sulfides and having at least 30% dihydrocarbyl tetrasulfide or higher sulfides; at least one non-acidic phosphorus component comprised of a trihydrocarbyl phosphite; at least one dihydrocarbyl dithiophosphate; and a phosphorus component comprising a dihydrocarbyl phosphite component is disclosed. | 2008-10-30 |
20080269086 | Functionalized nanosphere lubricants - A method of making a lubricant is disclosed. The method includes providing a hard nanosphere having a size of less than about 500 nanometers. The method also includes exposing the nanosphere to a radiation energy to at least partially bond a functional agent to a surface of the nanosphere. | 2008-10-30 |
20080269087 | Method of Lubricating an Internal Combustion Engine - The invention provides a method of lubricating an internal combustion engine comprising supplying to said engine a dispersion, the dispersion comprises: (a) a metal base; (b) a surfactant; and (c) an organic medium in which the metal base is uniformly dispersed by physical processes, wherein the metal base has a mean average particle size of at least 10 nanometres to less than 1 μm; and the dispersion has a solids content of greater than 15 wt %. The invention further provides a lubricant composition containing said dispersion. | 2008-10-30 |
20080269088 | 1,3,2-DIOXAPHOSPHORINANE, 2-SULFIDE DERIVATIVES FOR USE AS ANTI-WEAR ADDITIVES IN LUBRICANT COMPOSITIONS - The present disclosure relates to a non-acidic, sulfur-containing, phosphorus-containing compound of the formula I | 2008-10-30 |
20080269089 | Long life engine oil composition with low or no zinc content - A lubricating oil especially useful as a natural gas engine lubricating oil that has extended life as evidenced by reductions in viscosity increase, oxidation and nitration relative to current commercial and reference oils is provided. The oil comprises a major amount of a base oil of lubricating viscosity and a mixture of metallic detergents comprising: (i) a neutral calcium alkylsalicylate detergent and (ii) a second neutral or overbased metallic detergent or mixture of detergents other than neutral calcium alkylsalicylate selected from the group consisting of calcium and barium sulfonates, phenates and alkylsalicylates. The composition is further characterized as having low or no zinc. | 2008-10-30 |
20080269090 | Lubricating Compositions Containing Sulphonates - A lubricating composition containing (a) a detergent package containing (i) an oligomeric reaction product of (1) a hydrocarbyl-substituted phenol; (2) an aldehyde; and (3) a carboxyl-substituted phenol or a carboxyl-substituted phenylamine; and salts of the reaction product; (ii) a sulphonate; and (iii) optionally a phenate; (b) a dispersant; and (c) an oil of lubricating viscosity, wherein the sulphonate detergent is overbased with a metal ratio of about 12.5:1 to about 40:1. The composition is suitable for internal combustion engines, particularly marine diesel applications to provide improved cleanliness properties, antiwear performance or deposit control. | 2008-10-30 |
20080269091 | LUBRICATING COMPOSITION - There is disclosed a lubricant composition comprising a base oil, wherein the ratio of isoparaffins to normal paraffins in the base oil ranges from about 30 to about 400. | 2008-10-30 |
20080269092 | Oli composition for cutting and grinding by minimal quantity lubrication system - An oil composition for cutting and grinding by minimal quantity lubrication system and for sliding surface according to the present invention comprises an ester and a sulfur compound and/or a phosphorus compound. | 2008-10-30 |
20080269093 | Antiwear Polymer and Lubricating Composition Thereof - The present invention relates to the use of a RAFT polymer as an antiwear agent in a lubricant. The lubricant may be useful in a number of mechanical devices. | 2008-10-30 |
20080269094 | Solvated Nonionic Surfactants - The invention relates to a liquid and readily flowable composition includes (a) a room-temperature-solid solute comprising at least one nonionic surfactant, preferably having a hydrophilelipophile balance from about 11.1 to about 18.8, (b) at least one fatty alkanolamide; and (c) water, if needed. The fatty alkanolamide, which is substantially liquid at room temperature, solvates the solid solute to form a homogeneous composition which is liquid and readily flowable at room temperature. The select classes of nonionic surfactants include polyalkylene oxide carboxylic acid esters, ethoxylated fatty alcohols, poloxamers, alkyl polysaccharides, or combinations thereof. Useful alkanolamides include fatty diethanolamides. | 2008-10-30 |
20080269095 | SOLUBLE PATCH - An article, preferably a patch, containing:
| 2008-10-30 |
20080269096 | Formulations for Cleaning Ion-Implanted Photoresist Layers from Microelectronic Devices - A method and composition for removing bulk and ion-implanted photoresist and/or post-etch residue material from densely patterned microelectronic devices is described. The composition includes a co-solvent, a chelating agent, optionally an ion pairing reagent, and optionally a surfactant. The composition may further include dense fluid. The compositions effectively remove the photoresist and/or post-etch residue material from the microelectronic device without substantially over-etching the underlying silicon-containing layer(s) and metallic interconnect materials. | 2008-10-30 |
20080269097 | Lavatory Block Compositions - Improved treatment blocks useful in the treatment of lavatory appliances, particularly toilets are provided. The improved treatment blocks are solid block compositions which provide an extended service life, particularly when used in an ITB device. Methods of producing the solid block composition and treatment blocks therefrom, as well as methods of use are also disclosed. | 2008-10-30 |
20080269098 | Liquid Composition - A multi-chamber bottle comprises in one chamber a bleaching composition and in another chamber a bleach sensitive formulation. The viscosity of the bleaching composition is controlled by an admixture of a thickener and a hydrocarbon. The density of the bleaching composition is controlled by the presence of an ionic salt. | 2008-10-30 |
20080269099 | Low-builder, highly water-soluble, low-density solid laundry detergent composition - The present invention relates to a solid laundry detergent composition having a bulk density of from 100 g/l to 500 g/l, wherein the composition comprises: (a) from 1 wt % to 70 wt % anionic detersive surfactant; (b) from 0 wt % to 10 wt % zeolite builder; and (c) from 0 wt % to 10 wt % phosphate builder; wherein the composition comprises: (I) from 61 wt % to 90 wt % low-density particulate component, wherein the low-density particulate component has a bulk density of from 100 g/l to 426 g/l, and wherein the low-density particulate component comprises inorganic material and organic material; and (II) from 10 wt % to 39 wt % high-density particulate component, wherein the high-density particulate component has a bulk density of greater than 426 g/l; wherein the ratio of (i) the weight ratio of the inorganic material to the organic material comprised in the low-density particulate component (I) to (ii) the weight ratio of the inorganic material to the organic material comprised in the solid laundry detergent composition is from 0.3:1 to 5:1. | 2008-10-30 |
20080269100 | Layered Silicate Slurries Having a High Solids Content - What is described is a slurry comprising (a) at least 10% by weight of at least one sheet silicate, based on the total weight of the slurry; (b) an aqueous suspension medium and (c) a dispersing aid selected from at least one polyethylene glycol having a mean molecular weight of less than 90 000 and/or at least one polyacrylic acid in free acid form. Also described is a process for producing the slurry and the preferred used thereof. | 2008-10-30 |
20080269101 | Composition for use in the laundering or treatment of fabrics, and a process for making the composition - The present invention relates to an auxiliary composition, for use in the laundering or treatment of fabrics, comprising an admix of (i) clay and (ii) a silicone in an emulsified form. | 2008-10-30 |
20080269102 | 3-(2-Alkoxycarbonyloxy-Phenyl) Acrylic Acid Esters And Their Use As Precursors For The Delivery Of Olfactory Compounds - A compound of formula (I), their use as precursors and a method of their production | 2008-10-30 |
20080269103 | Diagnostic and Therapeutic Use of the Kcne4 Gene and Protein for Alzheimer's Disease - The present invention discloses the differential expression of the gene coding for KCNE4 protein in specific brain regions of Alzheimer's disease patients. Based on this finding, the invention provides a method for diagnosing or prognosticating Alzheimer's disease in a subject, or for determining whether a subject, is at increased risk of developing Alzheimer's disease. Furthermore, this invention provides therapeutic and prophylactic methods for treating or preventing Alzheimer's disease and related neurodegenerative disorders using the KCNE4 gene and its corresponding gene products. A method of screening for modulating agents of neurodegenerative diseases is also disclosed. | 2008-10-30 |
20080269104 | Methods For Enhancing the Quality of Life of a Growing Animal - The present invention provides methods for enhancing the quality of life of a growing animal by feeding the animal a quality of life enhancing amount of a composition comprising about 10% by weight protein, about 4% by weight fat, and about 0.05% by weight of at least one omega-3 polyunsaturated fatty acid. Enhanced quality of life is shown by an improvement in one or more characteristics selected from the group consisting of trainability, cognitive function, motor skills coordination or agility, retinal development, cartilage protection, maintenance of muscle mass, and skin and pelage quality. | 2008-10-30 |
20080269105 | Delivery of drugs - Formulations of drugs and crystalline side chain polymers to provide controlled and/or sustained release drug formulations. | 2008-10-30 |
20080269106 | Methods and Compositions for Diagnosis and Treatment of Disorders Involving Macrophages - The present invention discloses methods of identifying and treating diseases or disorders, particularly those relating to hormone receptors and their activities. The invention also discloses methods of screening for drugs that can be used to treat diseases or disorders. The invention is based, at least in part, on the discovery of the role of macrophages in development of certain cancers, such as prostate cancer and breast cancer. | 2008-10-30 |
20080269107 | Methods and Compositions for Treatment of Cancers with Hoxb4 - In some embodiments, without limitation, the invention comprises methods and compositions for the treatment of mammalian cancers, comprising the administration of HOXB4 protein and/or the overexpression of HOXB4 nucleotide sequence in order to induce apoptosis or otherwise decrease the survival of the target cancer cells. | 2008-10-30 |
20080269108 | Crystalline forms of the Di-Sodium Salt of N-(5-Chlorosalicyloyl)-8-Aminocaprylic Acid - The present invention relates to crystalline polymorphic forms of the di-sodium salt of N-(5-chlorosalicyloyl)-8-aminocaprylic acid, pharmaceutical compositions containing the same, methods of preparing the same, and methods for facilitating the delivery of active agents with the same. | 2008-10-30 |
20080269109 | SYSTEM AND METHOD OF RESUSCITATION OF A MAMMAL - The present disclosure provides systems and methods of saving people, organs, and cells from the injurious effects of ischemia and the injurious effects of reperfusion by providing artificial circulation while intentionally reducing for a period of rest the normal externally directed functions of the cells. | 2008-10-30 |
20080269110 | NON-BASIC MELANIN CONCENTRATING HORMONE RECEPTOR-1 ANTAGONISTS - The present application provides compounds, including all stereoisomers, solvates, prodrugs and pharmaceutically acceptable forms thereof according to Formula I. Additionally, the present application provides pharmaceutical compositions containing at least one compound according to Formula I and optionally at least one additional therapeutic agent. Finally, the present application provides methods for treating a patient suffering from an MCHR-1 modulated disease or disorder such as, for example, obesity, diabetes, depression or anxiety by administration of a therapeutically effective dose of a compound according to Formula I | 2008-10-30 |
20080269111 | METHOD OF TREATING DYSLIPIDEMIC DISORDER - The invention provides methods of treating or preventing a condition or disorder associated with dyslipidemia with compositions comprising apolipoprotein-sphingomyelin complexes. The methods of the invention permit reduction, by 4- to 20-fold, of the amount of apolipoprotein required for therapeutic administration to bring about an ameliorative effect. | 2008-10-30 |
20080269112 | Antineoplastic Agents Targeted via Glut Transporters - The present invention relates to novel antineoplastic agents and cancer diagnostic agents that specifically target neoplastic cells via the GLUT transportation system. More specifically, the invention relates to conjugates of 2-deoxyglucose, wherein a linker, which includes a covalent bond, is attached to 2-deoxyglucose at the 2 position, and the linker is attached to a therapeutic or diagnostic agent. The inventions also relates to methods of treating tumor disease and methods of making the novel compounds of the present invention. The agents of the present invention are superior to previous agents as they are targeted via GLUT transporters. | 2008-10-30 |
20080269113 | P53 BINDING T CELL RECEPTOR MOLECULES - The invention provides T-cell receptor (TCR) molecules comprising a Vα chain and a Vβ chain that bind peptides derived from the p53 protein, preferably, the human p53 protein. The TCR molecules include both heterodimeric molecules and single chain molecules which specifically bind a sequence preferably spanning about amino acid positions 264-272 of the p53 protein displayed in the context of an HLA molecule, preferably, HLA-A2.1. Also disclosed are methods for making and using such TCR molecules. The invention has a wide spectrum of useful application including therapeutic uses and use in the detection of cells expressing p53 protein. | 2008-10-30 |
20080269114 | Y4 Selective Receptor Agonists For Thereapeutic Interventions - Y4 receptor agonists selective for the Y4 receptor over the Y1 and Y2 receptors are useful for treatment of conditions responsive to activation of Y4 receptors. The Y4 selective agonists (a) are PP-fold peptide or PP-fold peptide mimics which have C— and N-terminal sequence features as specified in the description or (b) have an covalent intramolecular link, or (c) comprise two covalently linked C-terminal Y4 receptor-recognition amino acid sequences each of which comprises the last four residues of a C-terminal receptor recognition sequence of the type (a) agonists. | 2008-10-30 |
20080269115 | Immunogenic Sars Domain - Potentially antigenic, conserved and specific SARS-CoV peptides are disclosed. The disclosed polypeptides may be used in a variety of diagnostic and treatment methods for SARS infection. | 2008-10-30 |
20080269116 | Methods of Inhibiting Proinflammatory Cytokine Expression Using Ghrelin - The present invention provides a method of inhibiting proinflammatory cytokine expression using ghrelin. | 2008-10-30 |
20080269117 | Preparation for Use of Aspartate for Regulating Glucose Levels in Blood - The invention relates to the use of specific protein and/or peptide fractions having a high aspartate content for regulating plasma glucose concentrations and increasing insulin sensitivity in a mammal. The invention relates to a complete food fortified with aspartate equivalents as well as a supplement rich in aspartate equivalents that is given simultaneously with or even minutes up to an hour prior to the consumption of a meal comprising glucose. The nutritional or pharmaceutical composition contains at least one protein having a high aspartate content, preferably of soy or dairy origin, which is further enriched with aspartate equivalents from another protein and/or free aspartate equivalents. The protein fraction comprises glutamate equivalents in a weight ratio of aspartate equivalents to glutamate equivalents (asp:glu) between 0.41:1 and 5:1. | 2008-10-30 |
20080269118 | Use of Gpr100 receptor in diabetes and obesity regulation - We describe a method of identifying a molecule suitable for the treatment, prophylaxis or alleviation of a Gpr100 associated disease, in particular diabetes and obesity, the method comprising determining whether a candidate molecule is an agonist or antagonist of Gpr100 polypeptide, in which the Gpr100 polypeptide comprises the amino acid sequence shown in SEQ ID NO: 3 or SEQ ID NO: 5, or a sequence which is at least 90% identical thereto. | 2008-10-30 |
20080269119 | Ophthalmic Device and Related Methods and Compositions - Devices, methods, and compositions for improving vision or treating diseases, disorders or injury of the eye are described. Ophthalmic devices, such as corneal onlays, corneal inlays, and full-thickness corneal implants, are made of a material that is effective in facilitating nerve growth through or over the device. The material may include an amount of collagen greater than 1% (w/w), such as between about 10% (w/w) and about 30% (w/w). The material may include collagen polymers and/or a second biopolymer or water-soluble synthetic polymer cross-linked using EDC/NHS chemistry. The material may additionally comprise a synthetic polymer. The devices are placed into an eye to correct or improve the vision of an individual or to treat a disease, disorder or injury of an eye of an individual. | 2008-10-30 |
20080269120 | ADP-ribosyl transferase fusion variant proteins - The present invention relates to novel chimeric C3-like Rho antagonists and their use for promoting repair and neuron survival in injured mammalian central and peripheral nervous system and for treating or preventing cancer. | 2008-10-30 |
20080269121 | Methods and Compositions Involving A1c Subunit of L-Type Calcium Channels in Smooth Muscle Cells - The present invention concerns methods and composition for modulating the level of gene expression of the α | 2008-10-30 |
20080269122 | Antimicrobial Peptide Biocides - The present invention relates to retroviral constructs that encode novel monoclonal antibodies, novel fusion proteins, and chimeric monoclonal antibodies and to methods of using and producing the same. In particular, the present invention relates to methods of producing a fusion protein comprising a microorganism targeting molecule (e.g., immunoglobulin or innate immune system receptor molecule) and a biocide (e.g., bactericidal enzymes) in transgenic animals (e.g., bovines) and in cell cultures. The present invention also relates to therapeutic and prophylactic methods of using a fusion protein comprising a microorganism targeting molecule and a biocide in health care (e.g., human and veterinary), agriculture (e.g., animal and plant production), and food processing (e.g., beef carcass processing). The present invention also relates to methods of using a fusion protein comprising a microorganism targeting molecule and a biocide in various diagnostic applications in number of diverse fields such as agriculture, medicine, and national defense. | 2008-10-30 |
20080269123 | Methods for treating polycystic kidney disease (PKD) or other cyst forming diseases - The present invention is directed to methods of treating or ameliorating an effect of a polycystic disease. More particularly, the methods include administering to a patient in need thereof an amount of a modulator of a tumor necrosis factor (TNF) pathway, which is sufficient to treat or ameliorate an effect of a polycystic disease. Methods of treating or ameliorating an effect of a polycystic kidney disease (PKD) are also provided. Methods are also provided for identifying a candidate compound that may be effective to treat or ameliorate an effect of a polycystic disease or to increase polycystin-2 (PC2) function or decrease Rab11-Family of Interacting Protein2 (FIP2) function. Further provided are methods for identifying a patient having, or who is at risk for developing, a polycystic disease or who would benefit from treatment with a TNF-alpha inhibitor. | 2008-10-30 |
20080269124 | Stabilizer Molecule-Enriched Albumin Solution - The invention concerns a method for producing an aqueous albumin solution from a starting albumin solution which contains stabilizer molecules which are capable of occupying binding sites of the albumin, wherein in a method for increasing the albumin binding capacity (ABiC) for other molecules, at least a portion of the stabilizer molecules is removed from the albumin of the starting albumin solution and separated from the starting albumin solution. To carry out such a method, by means of which a stabilized commercial starting albumin solution can be prepared in a manner which is simpler, faster, cheaper and in a manner which is gently on the albumin by removing the majority of the stabilizers and increasing the albumin binding capacity, the method comprises steps in which the starting albumin solution is brought into contact with a solid adsorption material the affinity of which for at least a portion, preferably all of the stabilizer molecules is higher than the affinity of the albumin for the corresponding stabilizer molecules, and the albumin is separated from the adsorption material; wherein the method is carried out at a pH of >3. | 2008-10-30 |
20080269125 | Albumin Fusion Proteins - The present invention encompasses albumin fusion proteins. Nucleic acid molecules encodings the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors containing these nucleic acids, host cells transformed with these nucleic acids vectors, and methods of making the albumin fusion proteins of the intention and using these nucleic acids, vectors, and/or host cells. Additionally the present invention encompasses pharmaceutical compositions comprising albumin fusion proteins and methods of treating, preventing, or ameliorating diseases, disorders or conditions using albumin fusion proteins of the invention. | 2008-10-30 |
20080269126 | Albumin Fusion Proteins - The present invention encompasses albumin fusion proteins. Nucleic acid molecules encoding the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors containing these nucleic acids, host cells transformed with these nucleic acids vectors, and methods of making the albumin fusion proteins of the invention and using these nucleic acids, vectors, and/or host cells. Additionally the present invention encompasses pharmaceutical compositions comprising albumin fusion proteins and methods of treating, preventing, or ameliorating diseases, disorders or conditions using albumin fusion proteins of the invention. | 2008-10-30 |
20080269127 | Albumin Fusion Proteins - The present invention encompasses albumin fusion proteins. Nucleic acid molecules encodings the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors containing these nucleic acids, host cells transformed with these nucleic acids vectors, and methods of making the albumin fusion proteins of the intention and using these nucleic acids, vectors, and/or host cells. Additionally the present invention encompasses pharmaceutical compositions comprising albumin fusion proteins and methods of treating, preventing, or ameliorating diseases, disorders or conditions using albumin fusion proteins of the invention. | 2008-10-30 |
20080269128 | Albumin Fusion Proteins - The present invention encompasses albumin fusion proteins. Nucleic acid molecules encodings the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors containing these nucleic acids, host cells transformed with these nucleic acids vectors, and methods of making the albumin fusion proteins of the intention and using these nucleic acids, vectors, and/or host cells. Additionally the present invention encompasses pharmaceutical compositions comprising albumin fusion proteins and methods of treating, preventing, or ameliorating diseases, disorders or conditions using albumin fusion proteins of the invention. | 2008-10-30 |
20080269129 | POLYPEPTIDE AND DNA THEREOF USEFUL AS A NEOVASCULAR MARKER - A marker for neovascularization, vascular disease, inflammatory disease, entoptic neovascular disease, reproductive system disease, central nervous system disease and cancer, the method of detection of the marker and a diagnosis kit of the diseases are provided. Additionally, therapeutic agents of the diseases are provided. | 2008-10-30 |
20080269130 | Methods and compositions for treating hypoglycemic disorders - This invention relates to methods of treating and ameliorating congenital and neonatal hyperinsulinism and post-prandial hypoglycemia, comprising the step of administering an antagonist of the Glucagon-Like Peptide-1 (GLP-1) receptor, e.g. a GLP-1 fragment or analogue thereof. | 2008-10-30 |
20080269131 | Inhibitors of Akt Activity - Invented are novel 1H-imidazo[4,5-c]pyridin-2-yl compounds, the use of such compounds as inhibitors of protein kinase B activity and in the treatment of cancer and arthritis. | 2008-10-30 |
20080269132 | USE OF LOW TEMPERATURE AND/OR LOW PH IN CELL CULTURE - The present invention provides a novel method of reducing protein misfolding and aggregation in the cell culture by growing the cell culture at a reduced temperature and/or reduced pH. As a result, the quality of the protein produced in the cell culture is greatly improved. Thus, the present invention facilitates improvements in the efficacy of therapeutic proteins produced in cell culture. | 2008-10-30 |
20080269133 | COMPOSITIONS AND METHODS OF USE OF EPB1, AND ERBB3 BINDING PROTEIN - Inhibition of the proliferation of hormone refractory prostate cancer cells is achieved by administering EPB1, an ErbB3 binding protein, in combination with another anti-proliferation therapy such as administration of antiandrogens, other anticancer agents, radiation therapy, or surgery. Administration of EPB1 reverses the phenotype of hormone-resistant prostate cancer cells to hormone-sensitive prostate cancer cells. | 2008-10-30 |
20080269134 | DISODIUM SALTS, MONOHYDRATES, AND ETHANOL SOLVATES FOR DELIVERING ACTIVE AGENTS - The inventors have discovered that the disodium salt of certain delivery agents has surprisingly greater efficacy for delivering active agents than the corresponding monosodium salt. Furthermore, the inventors have discovered that the disodium salts of these delivery agents form solvates with ethanol and hydrates with water. The delivery agents have the formula | 2008-10-30 |
20080269135 | Method of treatment for early stage cancer - This patent describes a method and materials to treat cancer diagnosed at an early stage, particularly breast cancer. It considers that metastatic breast cancer growth includes periods of dormancy, that surgery to remove a primary tumor can induce metastatic growth, and that women with Down Syndrome rarely get breast cancer. It elevates the level of an antiangiogenic drug produced by chromosome 21 preferably Endostatin in plasma preferably at least one day prior to surgery and kept at that high level preferably indefinitely. The therapy specifically excludes drugs that significantly inhibit the VEGF pathway since that is important for wound healing. This method will prevent results of surgery from stimulating tumor growth and angiogenesis of micrometastatic disease that is much easier to prevent than control after the fact. This can be done indefinitely since there is no acquired resistance that develops, as happens in most cancer therapies. | 2008-10-30 |
20080269136 | METHOD OF USE OF PEPTIDE ANTAGONISTS OF ZONULIN TO PREVENT OR DELAY THE ONSET OF DIABETES - A method for preventing or delaying the onset of autoimmune diseases is disclosed. | 2008-10-30 |
20080269137 | COMPOSITIONS AND METHODS FOR MODULATING THE IMMUNE SYSTEM - A novel class of embryo derived peptides are described (Preimplantation factor) that were generated synthetically and were tested on peripheral blood immune cells and shown to block activated but not basal immunity, inhibiting cell proliferation and creating a T | 2008-10-30 |
20080269138 | Polyamides with tail structures - The present invention relates to polyamides with a tail comprising a linker and an end-group. A preferred end-group is isophthalic acid and derivatives thereof. Polyamides of the invention are capable of entering the nucleus of cells. Polyamides of the invention are capable of selectively binding DNA. The invention also relates to methods of using the polyamides in therapy and research. | 2008-10-30 |
20080269139 | FGF-5 Supported and Binding Peptides - The present invention provides peptides and supported peptides that bind to FGF-5. | 2008-10-30 |
20080269140 | Conformationally Constrained Smac Mimetics and the Uses Thereof - The invention relates to conformationally constrained mimetics of Smac which function as inhibitors of Inhibitor of Apoptosis Proteins. The invention also relates to the use of these mimetics for inducing apoptotic cell death and for sensitizing cells to inducers of apoptosis. | 2008-10-30 |
20080269141 | Peptide Substance Restoring Myocardium Function - The invention refers to the pharmaceutical means for the treatment of cardiovascular diseases and can be used as a substance restoring myocardium function in the course of treatment for different forms of this pathology. | 2008-10-30 |
20080269142 | ENDOGENOUS THIADIAZABICYCLO GLUTATHIONE-ADDUCT - This invention relates to mediators of apoptosis. Specifically, the invention relates to thiadiazabicyclo-4-oxo-2(E)-nonenal-Glutathione adduct as a novel agent for inducing apoptosis in cells depleted of GSH. | 2008-10-30 |