43rd week of 2021 patent applcation highlights part 8 |
Patent application number | Title | Published |
20210330524 | Transport Apparatus for a Weak Person - A transport apparatus has a mobile chassis, a lifting mechanism, two armpit supports structured and operated mirror-symmetrical to one another, and two seat assemblies. The lifting mechanism includes a lifting arm for assembling a chest rest and two lifting racks, and a linear actuator driving the lifting arm to pivot upward or downward. The armpit supports are assembled on the lifting racks and transversely extend toward a rear of the mobile chassis. The seat assemblies are assembled on the mobile chassis. Each of the seat assembly has a seat plate driven to rotate by a drive motor to form a seat. The weak person can be moved directly by the transport apparatus with voice command or with a remote control. Since the weak person is not moved by the care workers, the weak person can be moved in an easier and safer way. | 2021-10-28 |
20210330525 | Method for Using Patient-Turning Assemblies - Disclosed herein are patient-turning assemblies including a patient-turning assembly for turning a patient, which patient-turning assembly may include: a sling having: a first sling portion having a handle; and a second sling portion extending from the first sling portion; a sleeve fixedly coupled to the second sling portion; a channel disposed between the sleeve and the second sling portion; and a cushion capable of either ingress into or egress from the channel, or both. | 2021-10-28 |
20210330526 | Patient Support Apparatus For Removably Retaining Differently-Sized Portable Electronic Devices - A patient support apparatus for removably retaining differently-sized portable electronic devices. The patient support apparatus comprises a base, a litter with a patient support deck for supporting the patient, and a side rail. The side rail is coupled to the litter and arranged for movement relative to the base. The side rail includes a caddy comprising a back, a first brace, and a second brace spaced from the first brace. The first brace extends laterally from the back and defines a first bottom support region. The second brace extends laterally from the back and defines a second bottom support region converging toward the first bottom support region to arrange the first and second bottom support regions to provide differing points of contact for retaining differently-sized portable electronic devices. | 2021-10-28 |
20210330527 | BRAKE SYSTEM FOR A PATIENT SUPPORT APPARATUS - A brake system for a patient support apparatus including at least one wheel is disclosed. The brake system comprises a braking mechanism to be operatively coupled to at least one wheel of the patient support apparatus. The braking mechanism includes a first coupling portion movable between a lock position for locking the corresponding wheel, and an unlock position for allowing rotation of the wheel. The brake system comprises an actuating tool comprising a second coupling portion complementary to the first coupling portion of the braking mechanism and allowing removably connecting the actuating tool to the braking mechanism of the patient support apparatus. The first and second coupling portions are adapted for allowing engagement between the braking mechanism and the actuating tool to urge the braking mechanism between the lock and unlock positions, and are further adapted for allowing disengagement of the actuating tool from the braking mechanism. | 2021-10-28 |
20210330528 | ASSISTANCE SYSTEM - An assistance system includes an assistance device configured to assist movement of a care receiver; a microphone provided on the assistance device; a speech analyzer configured to analyze speech of at least one of a caregiver or the care receiver included in sound data acquired by the microphone and acquire information related to an action; an echo analyzer configured to analyze an echo included the sound data and acquire information related to a location; and an action history information generator configured to generate action history information of at least one of the caregiver or the care receiver based on the information related to the action and the information related to the location. | 2021-10-28 |
20210330529 | Rotatable bath seat with linear actuator - Disclosed is a movable bath seat device employing a linear actuator to assist an individual with decreased mobility in and out of a bathtub. The linear actuator employs a direct current motor with limit switches to move the seat between positions. The device permits an individual to take a position on the seat outside the bathtub and, by use of the actuator, move their torso to a position inside the bath tub side walls. The seat can then rotate, allowing an individual to lift their legs into the bathtub at their convenience. In a preferred embodiment, the cushion on the rotating seat assembly is constructed of a slip resistant padding comprised of medical grade, closed cell molded polyurethane padding that does not absorb water. | 2021-10-28 |
20210330530 | LIFT FOR FALLEN PERSON AT HOME - A household lift for fallen persons is devised in which a modified stepladder serves as the main lift structure while also serving as a stepladder storably foldable and usable within the house. A removable winch is set atop the stepladder, and it too can serve other purposes and can be of hand-cranked or electric powered design. The winch's lift cable is removably attached to preferably a prior-art sling type which first lays flat on the floor to facilitate moving the person onto it, and next pulls the person up into a secure sit-up position and then high enough to lower onto a wheelchair or other safe destination. | 2021-10-28 |
20210330531 | SUPPORT STRAPS HAVING FEATURES TO AID IN POSITIONING AND ROTATING A SUBJECT USING AN OVERHEAD LIFT, SYSTEMS AND KITS INCLUDING THE SAME, AND METHODS OF USING THE SAME - Support straps having features to aid in positioning and rotating a horizontally laying subject on a support surface, systems including the support straps, and kits of parts including the support straps are described herein. A support strap includes a body having first and second ends spaced a distance apart, at least one first loop extending from the first end, at least one second loop extending from the second end, and indicia on the body, the first loop, and/or the second loop. The indicia indicates an arrangement of the support strap with respect to the subject such that a centerline of the subject is not aligned with a true line of symmetry of the support strap when the first loop is coupled to a first end of a sling bar and the second loop is coupled to a second end of the sling bar. | 2021-10-28 |
20210330532 | LIFT AND METHOD FOR USE OF A LIFT FOR POSITIONING A PATIENT RELATIVE TO A SURGICAL FRAME - A lift, a head support, and methods for use thereof for use with a surgical frame are provided. The lift and the head support can be used with the surgical frame that is capable of reconfiguration before, during, or after surgery. The surgical frame can include a main beam that can be rotated, raised/lowered, and tilted upwardly/downwardly to afford positioning and repositioning of a patient supported thereon, and the lift and the head support can be used in lifting the patient from a table/gurney and positioning the patient with respect to the main beam. | 2021-10-28 |
20210330533 | CONVERTIBLY PREFABRICATED MODULAR INPATIENT UNIT WITH ENABLING CONTINUOUS RECONFIGURATION AND REDEPLOYMENT - The present invention provides an inpatient unit of modular design, built of recycled materials and environmentally friendly materials, allowing reconfiguration, redeployment and quick assembly, preventing indoor air from leaking, applicable to epidemic prevention and treating special patients, with high structural strength, lower cost and good environmental benefit. | 2021-10-28 |
20210330534 | PROTECTIVE BARRIER SYSTEM AND METHOD OF USING SAME - A protective barrier system that blocks and prevents infectious aerosols generated by or around a supine patient from escaping into a surrounding environment and reaching and contaminating a healthcare worker treating the patient with a patient interface device. The system includes a flexible, fluid-impervious sheet that covers the patient and blocks and prevents escape of the infectious aerosols into the surrounding environment. The sheet has an aperture that is adapted to enables access to the patient and couple to the interface device without gapping for blocking of the infectious aerosols and operative positioning of the system over and on the patient. A corresponding method is also disclosed. | 2021-10-28 |
20210330535 | PORTABLE NEGATIVE-PRESSURE MEDICAL/DENTAL PROCEDURES AND ISOLATION CHAMBER - A portable negative air pressure apparatus for isolating a treatment subject to permit a selected treatment procedure to be performed by a treatment operator. The apparatus comprises an air source connected to a closed chamber for sealable disposition over the head, neck and upper thorax of the treatment subject with the chamber having air ports, in and out. The chamber has rigid clear sides and a plurality of sealed ports, with the ports including sealed armholes for access, and with sealed gloves connected to the sealed armholes. The chamber also has at least one instrument hatch to permit introduction into the chamber of instruments for carrying-out the selected treatment procedure. | 2021-10-28 |
20210330536 | LIFT AND METHOD FOR USE OF A LIFT FOR POSITIONING A PATIENT RELATIVE TO A SURGICAL FRAME - A lift, a head support, and methods for use thereof for use with a surgical frame are provided. The lift and the head support can be used with the surgical frame that is capable of reconfiguration before, during, or after surgery. The surgical frame can include a main beam that can be rotated, raised/lowered, and tilted upwardly/downwardly to afford positioning and repositioning of a patient supported thereon, and the lift and the head support can be used in lifting the patient from a table/gurney and positioning the patient with respect to the main beam. | 2021-10-28 |
20210330537 | HEAD SUPPORT AND METHOD FOR USE OF THE HEAD SUPPORT FOR POSITIONING A PATIENT RELATIVE TO A SURGICAL FRAME - A lift, a head support, and methods for use thereof for use with a surgical frame are provided. The lift and the head support can be used with the surgical frame that is capable of reconfiguration before, during, or after surgery. The surgical frame can include a main beam that can be rotated, raised/lowered, and tilted upwardly/downwardly to afford positioning and repositioning of a patient supported thereon, and the lift and the head support can be used in lifting the patient from a table/gurney and positioning the patient with respect to the main beam. | 2021-10-28 |
20210330538 | SLIDING JAW THRUST DEVICE - A device and method that facilitates performance of a jaw thrust maneuver. A base connected to a rack and pinion mechanism including at least one pinion rotatably attached to the base and at least two racks slidably attached to the base and engaged with the pinion to move in opposite directions upon rotation of at least one pinion. A pair of arms, each pivotably coupled to one of the racks to allow rotational freedom of motion. A patient's head is placed in supine position and a pair of arms slides towards the patient's head in synchrony to position the arms to clear the patient's airways. | 2021-10-28 |
20210330539 | MASSAGE DEVICE AND SYSTEM - A massage kit having a foam roller, a massage device, and a removable cover. The massage device includes a flat bottom surface with a curved top surface. Protrusions extend from the massage device and are configured to interact with the removable cover to hold the cover in place on the top surface or the bottom surface of the massage device. The roller includes an opening sized and dimensioned to receive the massage device. | 2021-10-28 |
20210330540 | SYSTEM FOR ASSISTING AN OPERATOR IN A WORK STATION - A system for assisting an operator in a work station includes a collaborative robot, with a robot electronic controller, configured for conducting an operation in an open, non-protected space, adjacent and in cooperation with the operator, an exoskeleton including one or more actuators, wearable by the operator for receiving assistance in conducting one or more operations, a plurality of sensors associable to the body of the operator and configured for detecting at least one parameter. An electronic controller is configured for receiving signals by the sensors and for sending signals to the one or more actuators of the exoskeleton and to the robot controller based on an elaboration of signals received by the sensors, wherein the system controller is configured and programmed for dynamically controlling the exoskeleton and the robot so as to avoid collisions or injuries between the robot and the operator or conditions of lack of safety for the operator, and to enable the robot to cooperate with the operator by assuming positions suitable to the physical and physiological features, to the workload and to the postures of the operator. | 2021-10-28 |
20210330541 | TENSILE FORCE GENERATING DEVICE AND BENDING AND STRETCHING MOTION ASSIST DEVICE PROVIDED WITH SAME - To allow the elastic member to smoothly expand and contract while suppressing increase in size and preventing curving of the elastic member, a tensile force generating device ( | 2021-10-28 |
20210330542 | VESTIBULAR TRAINING APPARATUS AND METHOD OF USE - A vestibular training apparatus and method as disclosed and claimed. Wherein the training apparatus comprises a motorized rotational platform, an adjustable body harness, a swivel coupling attached to the adjustable harness, a beam anchor, and pulley system. The pulley system in connection with the beam anchor allows a user to be lifted by the trainer after rotating on the motorized rotational platform, wherein the user continues to rotate after being lifted by the trainer as a result of inertia. | 2021-10-28 |
20210330543 | INFLATABLE MASSAGE SHOES - An inflatable massage shoe includes a sole, a vamp installed on the sole, and an inflatable massage device having a main airbag and a massage airbag connected to the main airbag. The main airbag is installed on the sole and has an elastic device installed in the main airbag; the massage airbag is installed on an inner side of the vamp and communicated with the main airbag through a pipeline, and a gas in the main airbag can be exchanged with the gas in the massage airbag through the pipeline; and the vamp further includes a protective shell and an inner lining, and the massage airbag is installed between the protective shell and the inner lining. This inflatable massage shoe provides active massage actions, simulates the massage effect, and improves the comfortability, practicality, and promotion of massage shoes. | 2021-10-28 |
20210330544 | EXTERNAL COUNTERPULSATION SYSTEM AND METHOD OF CONTROLLING SAME - The present invention relates to an external counterpulsation system that senses biosignals to monitor a heart condition and performs external counterpulsation on the basis of the monitored heart condition. The external counterpulsation system includes: a compression device wrapping around limbs of a subject to compress or decompress the wrapped limbs; and a controller configured to calculate compression timing and decompression timing for the external counterpulsation by analyzing an electrocardiogram signal and a blood flow rate signal among the sensed biosignals, and control the compression device on the basis of the calculated compression timing and decompression timing. As described above, the present invention can automatically control compression timing and decompression timing, thus ensuring that, unlike the related art technology, the problem of inconvenience that an operator has to control the compression and decompression timings while continuously monitoring procedure is solved, and that operators without specialized knowledge can use the system easily. | 2021-10-28 |
20210330545 | FEMALE STIMULATION DEVICE - A female stimulation device includes a head portion and a handle portion connected to and extending from the head portion. The head portion includes a suction surface and a suction chamber positioned on the suction surface. The stimulation device also includes a suction motor connected to the suction chamber and a plurality of vibration motors adjacent to and connected to the suction chamber. | 2021-10-28 |
20210330546 | SYSTEM, APPLICATION, AND PROCESS FOR EXERCISE RECOVERY - Systems and processes for recommending a recovery routine are described. In various embodiments, an online or mobile application can receive activity data from a user and provide recommended recovery routines based thereon. The activity data can be received from a wearable activity tracker device and/or a smart fitness machine. The application can recommend that the recovery activity be performed using a smart recovery device (e.g., a percussive massage device). In certain instances, data from the recovery activity can also be communicated to the application and compared against an optimal recovery routine. | 2021-10-28 |
20210330547 | SYSTEMS AND METHODS FOR CONTROLLING THE EFFECTS OF TREMORS - A system for treatment of involuntary muscle contraction includes a wearable interface having an internal contact surface, the wearable interface configured to at least partially encircle a first portion of a limb of a subject, and an energy applicator carried by the wearable interface and configured to apply energy of two or more types to the limb of the subject. The system may further comprise a control unit configured to control the operation of the energy applicator. | 2021-10-28 |
20210330548 | A PAIN MANAGEMENT DEVICE - The invention relates to a pain management device with a body portion having an hourglass shaped, elongated handle with an arm at one end for releasably attaching one or more treatment attachments, one or more generally planar scraping wings for Gua Sha treatment, and a motor inside configured to impart vibration in each of several modes optimized for vibration therapy. The invention may also include a kit with the pain management device, and one or more treatment attachments designed for unilateral or bilateral vibration application adjacent to trigeminal and/or vagus nerves. The treatment attachment may have two or more pivotable arms that extend along an axis generally perpendicular to the elongated handle when attached to the pain management device. | 2021-10-28 |
20210330549 | Device and Method for Assisting Breathing in a Subject - A distension/compression device for assisting breathing in a subject is disclosed. In one embodiment, a first tube includes a flexible and elastic material that forms a first tube lumen extending from a proximal end to a distal end of the first tube. Longitudinal expansion of the first tube is restricted less than radial expansion of the first tube. A connection element including a first air supply port is in fluid communication with an open proximal end of the first tube lumen and attached to a proximal end of the first tube. A method for assisting breathing of a patient and a method for assisting the clearing of secretions is also included. | 2021-10-28 |
20210330550 | Hot Stone Placement Pad Systems and Methods - A hot stone placement pad includes a number of retaining pockets, each configured to hold a corresponding stone during a session, wherein substantially all of the retaining pockets face inward toward the central axis of the pad such that the pad may be grasped at opposite ends and lifted from the client's body while the stones remain in their respective pockets. The dimensions of the pad and the positions of the retaining pockets may be scaled to the client's body size. | 2021-10-28 |
20210330551 | METHOD FOR EXTRACORPOREAL BLOOD PURIFICATION AND DIALYSATE DISPOSAL - A method for extracorporeal blood purification and dialysate disposal includes the steps of: passing a patient's blood through a dialyzer through a first line, passing dialysate through the dialyzer through a second line so that the dialysate exits the dialyzer as used dialysate, and collecting the used dialysate in a container. The container can include an inlet and an outlet connector, the inlet being fluidly connected to the dialyzer to receive the used dialysate, and the outlet connector being fluidly connected to a sewer line of a sewage system in a sealed manner to discharge the used dialysate directly into the sewage system. | 2021-10-28 |
20210330552 | STERILIZATION FLUID PATH WITH BARRIER REMOVAL - A device and method is disclosed for assembling a container holder in a clean environment, aseptically adding a solution to a primary container, inserting the primary container into the container holder, applying a first barrier to the container holder, sterilizing the container holder comprising the primary container and the applied first barrier to provide a sterilized container holder, assembling a fluid path module in a clean environment, the assembling comprising applying a second barrier to a first end of the sterilized fluid path module, sterilizing the fluid path module to provide a sterilized fluid path module and assembling a delivery device comprising the sterilized container holder and the sterilized fluid path module. | 2021-10-28 |
20210330553 | CAP FOR SPOUT AND MODIFIED SPOUT - An improvement to a standardized design of a body for small-bore connectors for liquids and/or gases in a healthcare application, wherein the body has a spout with a standardized upper portion. The upper portion can have a standardized external thread or can have a different size and shape for the external thread. The body can have a standardized internal flange or another differently sized and shaped internal flange. The body can have an internal void though which the liquids and/or gases flow. At least a portion of the standardized internal flange or another internal flange can be eliminated or removed to reduce a flow restriction caused by the standardized internal flange and thus increase a flow area of the internal void. | 2021-10-28 |
20210330554 | SYSTEM FOR CLOSED TRANSFER OF FLUIDS - A system for the closed transfer of fluids that provides substantially leak-proof sealing and pressure equalization during engagement of a cannula with a vial, during transfer of a substance from a vial chamber to a barrel chamber via the cannula, and during disengagement of the cannula from the vial is disclosed. The leak-proof sealing of the system substantially prevents leakage of both air and liquid during use of the system. The system of the present disclosure also permits pressure equalization between a vial and the system when the system is attached to the vial. The system is compatible with a needle and syringe assembly for accessing a medication contained within a vial for administering the medication to a patient. | 2021-10-28 |
20210330555 | HERBAL DECARBOXYLATION AND INFUSION SYSTEM - A system for decarboxylating and infusing an organic material is disclosed, including a heated reservoir including a spout to fittingly engage with a complimentary portion of a housing. The decarboxylation and infusion apparatus is in operable communication with a touchscreen user interface whereon a user selects decarboxylation and infusion settings, the heated reservoir including a mixing element to agitate an organic material and solvent disposed therein, the spout to prevent counterrotation caused by the mixing element. A fan actively cools the heated reservoir, the fan in communication with a vent having a filter, the vent to expel and deodorize air emitted therefrom. | 2021-10-28 |
20210330556 | COSMETIC COMPOSITION INCLUDING MICROSPHERES CONTAINING HIGH CONCENTRATION OF OXYGEN AND METHOD OF PREPARING THE SAME - The present invention provides a cosmetic composition including oxygen-containing microspheres for preventing skin aging, in which the microsphere contains 25 to 35 ppm of oxygen. The cosmetic composition including the microsphere according to the present invention is capable of supplying a high concentration of oxygen to the skin by allowing a high concentration of oxygen to slowly release through the microspheres. | 2021-10-28 |
20210330557 | Oral cavity cleaning composition, method, and apparatus - An oral hygiene composition includes a mixture of: (i) a carrier liquid; and (ii) a water-insoluble hydratable polymer fibers forming an entangled three-dimensional network of said water-insoluble hydratable polymer fibers in said carrier; wherein: said carrier liquid comprises one or more humectant in a concentration of total humectant in excess of 5 wt. % based on the weight of the composition; said composition has an elastic modulus G′ and a loss modulus G″, and said elastic modulus G′ is larger that said loss modulus G″; and said water-insoluble hydratable polymer fibers have a diameter of about 10 to about 20,000 nm and a length of at least 100 nm. | 2021-10-28 |
20210330558 | OIL-IN-WATER EMULSION COSMETIC - The invention relates to an oil-in-water emulsion cosmetic which contains 2 to 10 mass % of a self-water-dispersible crosslinked silicone elastomer, at least one of a nonionic surfactant having HLB of 12.5 or more and a water-soluble polymer having emulsifying capability and a silicone oil having a kinematic viscosity at 25° C. of 20 mm | 2021-10-28 |
20210330559 | OIL-IN-WATER EMULSION COSMETIC COMPOSITION - An oil-in-water emulsion cosmetic composition is provided. The oil-in-water emulsion cosmetic composition comprises a carboxylic acid modified silicone (A) that has a specific chemical structure and is liquid at room temperature, an oil agent (B), and water (C). The oil-in-water emulsion cosmetic composition can provide a cosmetic film with high stability and excellent water resistance. | 2021-10-28 |
20210330560 | COSMETIC GEL COMPRISING A TRIGLYCERIDE OIL - According to the invention, a cosmetic gel is provided comprising multilamellar vesicles dispersed in an aqueous phase, wherein the multilamellar vesicles have the shape of a rotational body comprising two or more concentric lipid double layers, the cosmetic gel comprising:
| 2021-10-28 |
20210330561 | METHOD OF MANUFACTURING DERMATOLOGICALLY ACTIVE SUBSTANCE VEHICLE HAVING MULTILAYER STRUCTURE, AND COMPOSITION MATERIAL FOR FUNCTIONAL COSMETIC CONTAINING DERMATOLOGICALLY ACTIVE SUBSTANCE VEHICLE MANUFACTURED USING THE SAME - Disclosed is a method of manufacturing a dermatologically active substance vehicle having a multi-layer structure and a composition material for a functional cosmetic containing a dermatologically active substance vehicle manufactured using the same. The method includes manufacturing a hydrogenated lecithin dispersion solution by adding hydrogenated lecithin to purified water at 70 to 90° C. with agitation to thus perform dispersion, manufacturing a pre-emulsion base by adding saturated fatty alcohol having 12 to 22 carbon atoms to the hydrogenated lecithin dispersion solution at 70 to 90° C. with agitation to thus perform dispersion, manufacturing an emulsion base by adding the pre-emulsion base and a water-soluble substance to the purified water at 70 to 90° C. with agitation to thus perform dispersion, and manufacturing a multi-layer globule including phospholipid bilayers by adding oil to the emulsion base at 70 to 90° C. with agitation to thus perform dispersion. | 2021-10-28 |
20210330562 | Cosmetic Ink Composition Comprising A Surface Tension Modifier - A cosmetic ink composition comprises a particulate material, a polymeric dispersant, a rheology modifier, and a surface tension modifier, wherein the surface tension modifier is selected from the group consisting of C1-C16 alcohols, C5-C18 diols, and mixtures thereof. The particulate material can have a Particle Size Distribution D50 of about 100 nm to about 2,000 nm. The rheology modifier can be selected from the group consisting of alkali swellable emulsion polymers, hydrophobically modified alkali swellable emulsion polymers, and combinations thereof. The cosmetic ink composition can have a surface tension of from about 20 to about 45 mN/m. | 2021-10-28 |
20210330563 | Multi-Chrome Cosmetic Hair Composition - A multi-chrome cosmetic hair composition is disclosed. The composition includes a base formula suitable for hair and an interference pigment providing a colored background exhibiting interference colors that are observable at different angles of observation. The formula is sufficient to enable a homogenous suspension of the interference pigment. The formula includes a propellant, denatured alcohol, neutralized octylacrylamide/acrylates/butylaminoethyl methacrylate copolymer 4, a neutralizing agent sufficient to neutralize the octylacrylamide/acrylates/butylaminoethyl methacrylate copolymer 4 to a range of 80% to 100%, and a plasticizer. The interference pigment includes an opaque-type interference pigment consisting of particles ranging from 5 microns to 60 microns in size to fill in gaps on hair shaft surfaces and create a smooth, chrome-like effect on the hair. The interference pigment includes an inorganic layer that specularly reflects incident light and semi-transparent inorganic layers that refract the reflected light such that the interference colors are observable. | 2021-10-28 |
20210330564 | AQUEOUS ORAL CARE COMPOSITIONS - Disclosed herein are aqueous oral care compositions and methods of making such compositions. One aspect of the aqueous oral care composition comprises sodium bicarbonate, glycerin, sodium gluconate, erythritol, magnesium chloride, zinc citrate, and potassium citrate. Additional aspects include methods for making an aqueous oral care composition. | 2021-10-28 |
20210330565 | Rheological Solid Composition for use in Personal Care Compositions - A rheological solid composition comprising a crystallizing agent and an aqueous phase. | 2021-10-28 |
20210330566 | WATER-SOLUBILIZED MIXTURE OF GINSENOSIDE COMPOUND K AND METHOD OF WATERSOLUBILIZING GINSENOSIDE COMPOUND K - Disclosed is a water-solubilized mixture of ginsenoside compound K manufactured by mixing hexanediol and polyol with ginsenoside compound K and then adding water, and a method of water-solubilizing ginsenoside compound K. The method includes manufacturing a mixture of ginsenoside compound K powder and hexanediol by adding hexanediol to ginsenoside compound K powder and performing mixing, manufacturing a mixture of ginsenoside compound K powder, hexanediol, and polyol by adding polyol to the mixture of ginsenoside compound K powder and hexanediol and performing mixing, and manufacturing an aqueous solution containing ginsenoside compound K by adding the mixture of ginsenoside compound K powder, hexanediol, and polyol to water at 65 to 75° C. during agitation and performing mixing. The water solubility of ginsenoside compound K is improved, and cosmetics including high concentrations of ginsenoside compound K are readily manufactured. | 2021-10-28 |
20210330567 | COMPOUNDS AND COMPOSITIONS FOR USE - The present disclosure provides compounds and compositions which may be used to augment, supplement and/or replace the products of certain UV sensitive/dependent processes. In particular, the disclosure provides sunscreen compositions which avoid problems associated with prior art sunscreen compositions which inhibit the natural progression of certain in vivo sunlight/UV dependent processes including processes which result in Nitric Oxide/Vitamin D production in the skin. | 2021-10-28 |
20210330568 | TOPICAL COSMETIC COMPOSITIONS - The present invention relates to compositions for topical administration to a user's skin that provide a number of dermatological benefits. The compositions include a unique combination of vitamins and additional ingredients that work together to increase skin firmness and decrease wrinkles. | 2021-10-28 |
20210330569 | COSMETIC COMPOSITION AND METHODS OF USE THEREOF - Disclosed is a topical skin composition. The composition can include water, caprylic/capric triglyceride, | 2021-10-28 |
20210330570 | FILM-FORMING COMPOSITION BASED ON LEGUMINOUS STARCH FOR COSMETIC USE - The present invention relates to novel film-forming compositions having good mechanical strength during application and also an ability to be easily eliminated or removed by water washing. The invention also relates to cosmetic care or make-up compositions comprising a film-forming composition as well as to their non-therapeutic uses. | 2021-10-28 |
20210330571 | OIL-IN-WATER TYPE EMULSION COSMETICS - Provided is an oil-in-water emulsion cosmetic composition having a high UV protection or blocking effect (particularly, boost effect of SPF value) and excellent water resistance and the like of a film (e.g., cosmetic film) without impairing the tactile sensation or the feeling of use particular to the oil-in-water emulsion cosmetic composition. The oil-in-water emulsion cosmetic composition comprises: (A) a carboxylic acid-modified silicone in a liquid form at 50° C., (B) a vinyl-based polymer emulsion, (C) a basic compound, and (D) an inorganic UV protecting agent consisting of hydrophobic fine particulate metal oxide. The oil-in-water emulsion cosmetic composition is useful. | 2021-10-28 |
20210330572 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE HYDROPHOBIC FILM-FORMING POLYMER AND AT LEAST ONE AMINOSILICONE - The present invention relates to a cosmetic composition comprising a combination of at least one hydrophobic film-forming polymer chosen from hydrocarbon-based resins, and of at least one aminosilicone in an organic solvent. The present invention also relates to a cosmetic process for treating keratin fibres, in particular human keratin fibres such as the hair, using said cosmetic composition. Finally, the present invention relates to the use of said cosmetic composition for conditioning keratin fibres, in particular human keratin fibres such as the hair. | 2021-10-28 |
20210330573 | METHOD OF EMULSIFICATION USING CORE-CORONA TYPE MICROPARTICLES - A method of emulsification of an oil phase in an aqueous continuous phase, by dispersing core-corona microparticles into the aqueous phase, adding the oil phase, and applying shearing force for a time sufficient to emulsify the resulting mixture. The core-corona microparticles are obtained by radical co-polymerization of a polyethylene oxide macromonomer with at least one hydrophobic acrylate monomer and at least one hydrophobic acrylamide monomer. | 2021-10-28 |
20210330574 | EXTERNAL PREPARATION FOR CONCEALING ROUGHNESS - An objective of the present invention is to provide an external preparation for concealing roughness that is easy to spread when applied, while also having effects of concealing roughness such as fine wrinkles. The external preparation for concealing roughness of the present invention comprises (a) 1% to 15% by mass of a wax; and (b) 4% to 25% by mass of a non-spherical powder; and has a viscosity of 50,000 to 150,000 mPa·s. | 2021-10-28 |
20210330575 | COSMETIC COMPOSITION FOR SKIN WHITENING AND WRINKLE IMPROVEMENT COMPRISING ADVENTITIOUS ROOT EXTRACT OF CENTELLA ASIATICA AS EFFECTIVE INGREDIENT - A composition for skin whitening and wrinkle improvement includes an adventitious root extract of | 2021-10-28 |
20210330576 | Magic Skin Repair Serum - The present invention discloses an advance enhanced stability, enhanced solubility and an enhanced photoprotective effect by proposing an improved process by presenting a technique where the skin care products inform of serum is presented. The proposed method provides compositions with necessary ingredients including but not limited to Organic rose hip oil, organic wheat germ, organic Gotu kola, organic onion seed oil and vitamins such as A, B3, B5 and E containing cosmetics used to address age, wrinkles, stretch marks, dark spots, spider veins, razor bumps, ingrown hair, loose and soggy skin and environmental induced damage. | 2021-10-28 |
20210330577 | METHOD FOR ELIMINATING ODORS COMPRISING A DEODORANT COMPOSITION CONTAINING OPUNTIA FICUS EXTRACT OR PERSIMMON JUICE - Disclosed is a method for eliminating odors including administering a deodorant composition containing an | 2021-10-28 |
20210330578 | TOPICAL COSMETIC COMPOSITIONS - The present invention relates generally to methods of use and compositions for enhancing skin hydration in a person, attracting and binding moisture in the air to the skin's outer layers, transporting surface moisture below the skin's stratum corneum, increasing skin moisture content, plumping and tightening the skin, protecting the skin from moisture loss to the environment, supporting optimal skin barrier function, and/or stimulating production of the skin's own Natural Moisturizing Factor. The composition includes a combination of the | 2021-10-28 |
20210330579 | SKIN CARE FORMULATION - There is provided a formulation for skin rejuvenation comprising lyophilised umbilical cord plasma comprising at least one active chemokine, at least one growth factor and at least one cytokine; a transdermal carrier; and a liposomal base, wherein at least a portion of the lyophilised umbilical cord plasma and transdermal carrier are contained within liposomes of the liposomal base. There is also provided a dosage form for skin rejuvenation comprising 1-5% (w/w) lyophilised umbilical cord plasma comprising at least one active chemokine, at least one growth factor and at least one cytokine; 85-95% (w/w) polyethylene glycol; and 0.1-2% (w/w) gum acacia. | 2021-10-28 |
20210330580 | PORE MINIMIZER - A method for reducing the appearance of a skin pore in skin of a subject in need thereof is disclosed. The method can include topically applying to the skin pore a composition comprising effective amount of | 2021-10-28 |
20210330581 | COSMETIC COMPOSITIONS - A method of treating skin with a composition is disclosed. The method can include topically applying an effective amount of a composition to skin in need thereof, wherein the composition comprises an aqueous extract of plankton comprising an exopolysacchride synthesized by | 2021-10-28 |
20210330582 | Compositions Comprising Antioxidant, Fluid Dispensers, and Methods Involving the Same - A composition includes a salt; a polymer; and an antioxidant. A dispenser includes a flexible container having a closed end and an opposed open end; an osmotically-effective solute composition encapsulating at least a portion of the container, the solute composition including antioxidant in an amount of at least 0.5 wt %, based on weight of the solute composition; a semipermeable membrane encapsulating the osmotically-effective solute composition; a cap having a sealing surface adapted for sealing engagement with the open end of the container; and a port extending from an interior of the container and through the cap. Also disclosed are methods of making and using the composition and osmotic pumps. | 2021-10-28 |
20210330583 | Promoting and enabling for the growth of more hair volume with a lotion made from the radish, garlic, and vitamin E oil combined at room temperature. - The task of initiating a 20 minutes cycle of skin temperature regulation through Gibs Free Energy and sets in the breaking down of the nutrients for skin absorption by taking advantage of assimilating the mechanism of sebaceous gland's function in relation to the growth and maintenance of hair with radish, garlic, and vitamin E oil. | 2021-10-28 |
20210330584 | TOPICAL PREPARATIONS OF DRUG DELIVERY FOR NASAL AND SINUS IRRIGATION - Embodiments of the application are directed toward a liquid topical sinus therapy for a patient, comprising a medicated formulation including at least one medication, and a device for delivering the medicated formulation to the patient's nostrils, nasal passages, or sinuses. The medicated formulation may include drugs selected from the group consisting of corticosteroids, antibiotics, antifungals, antihistamines as well as herbal and alternative medications. Dosage forms include powders, tablets and gels which facilitate clinical testing and enable patient compliance. | 2021-10-28 |
20210330585 | METHOD FOR REDUCING PARASITE BURDEN IN A MOSQUITO - Described herein are methods and compositions for reducing transmission of | 2021-10-28 |
20210330586 | AZOLE COMOPUND OPHTHALMIC PREPARATION - An ophthalmic pharmaceutical composition containing an azole compound, a method for preparing the same, as well as a use of the pharmaceutical composition in the preparation of an ophthalmic preparation for preventing and treating ophthalmic diseases. The ophthalmic preparation contains the azole compound at a concentration of 0.005-400 μM. | 2021-10-28 |
20210330587 | ORAL SANITIZER AND IMMUNE SUPPORT FOR VIRAL AND BACTERIAL PREVENTION - An oral sanitizer composition with immune support for viral, bacterial and COVID-19 prevention. The oral sanitizer composition formulated into a mouthwash, a mouth rinse, a mouth strip a throat lozenge, a mouth spray, a throat spray or a nasal spray. The oral sanitizer composition being formulated with alcohol and without alcohol. | 2021-10-28 |
20210330588 | COMPOSITIONS AND METHODS FOR ADMINISTERING ANESTHETICS - Compositions and methods of use related to formulations comprising anesthetics are generally described. Some embodiments are directed to compositions comprising a plurality of micelles and/or particles, and an anesthetic contained internally. These can be used to control and/or prolong the duration of IVRA while reducing the risk of systemic toxicity commonly due to administering anesthetics. The control and/or prolonged duration of IVRA may be due, at least in part, to the attachment of the sufficiently small micelles and/or particles to a biointerface (e.g., blood vessel surface) where the composition has been administered. Conventional IVRA methods commonly do not utilize potent and long-acting anesthetics (e.g., bupivacaine) due to the risks of cardiac toxicity. The compositions and methods described herein, however, provide a pathway for increased safety and efficiency of the use of such anesthetics, in certain embodiments. Resultantly, the performance (e.g., anesthetic distribution) of the micelles and/or particles internally containing an anesthetic may be comparatively better than the performance of free anesthetic, e.g., with respect to nerve blood and systematic drug distribution. | 2021-10-28 |
20210330589 | METHOD OF ENCAPSULATING ACTIVE INGREDIENTS IN LIPOSOMES - A method for encapsulating active ingredients in liposomes having an active ingredient solution encapsulated with a bilayer composed of two monomolecular layers of a first and a second amphiphilic compound, wherein the method comprises:
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20210330590 | AGENTS FOR ORAL COMPOSITION - The disclosure provides compositions and products configured for oral use. For example, a composition is provided that includes a foam containing a lipid and an active agent and/or a flavorant, and a carrier, wherein the foam is adsorbed onto the carrier. Such a foam can be incorporated, e.g., within lozenges and/or pouched oral products. The disclosure further provides an oral product (e.g., a lozenge and/or pouched oral product) including an encapsulated agent, wherein the encapsulated agent is a porous bead with an exterior portion and an interior portion containing a lipid and an active agent and/or a flavorant. | 2021-10-28 |
20210330591 | CURCUMINOID COMPOSITES - The present invention relates to a melt composite comprising one or more curcuminoids and a carrier selected from rice bran extract, mannitol, maltodextrin and mixtures thereof. The invention also provides a process for preparation of the melt composite, wherein the mixture of curcuminoids, rice bran extract, mannitol, maltodextrin and mixture thereof may be subjected to controlled conditions of heating and granulation. The melt composite may also be optionally comprised of one more excipient suitable for use for human consumption. Curcuminoid composites can be formulated in suitable solid, liquid or semisolid compositions. Curcuminoid composites and the compositions thereof, exhibit rapid dissolution and enhanced bioavailability. | 2021-10-28 |
20210330592 | STABILIZER-CONTAINING SOLID DRUG FORMULATION - An object of the present invention is to provide a solid drug formulation having excellent stability. The solution according to the present invention is a solid drug formulation containing: | 2021-10-28 |
20210330593 | Structured solid dosage form - At present, the most prevalent pharmaceutical dosage forms, the oral immediate-release tablets and capsules, are porous solids of compacted drug and excipient powders. Upon ingestion, physiological fluid percolates the open pores, and the dosage form disintegrates and the drug dissolves. Because the pores in the compacted solids are not well connected, however, fluid percolation generally is not uniform, and the drug release rate is difficult to predict and control. To overcome such limitations, therefore, herein a structured solid dosage form is disclosed. The structured solid dosage form comprises a structural assembly of one or more repeatably arranged, extruded structural elements. The elements comprise segments separated and spaced from adjoining segments by free spacings defining one or more substantially interconnected free spaces, or channels, in the dosage form through which a physiological fluid may percolate. The disclosed dosage form enables more predictable drug release rates, and can be readily manufactured by 3D-printing. | 2021-10-28 |
20210330594 | Fast-Acting Soft Gelatin Capsules Containing A Mixture Of Pain Reliever/Fever Reducer, Diuretic And Antihistamine - Fast-acting, bioavailable liquid softgel fill compositions comprising (a1) a pain reliever/fever reducer; (a2) a diuretic; (a3) an antihistamine; (b1) a pharmaceutically acceptable polyalkylene glycol; (b2) a pharmaceutically acceptable alkylene glycol; (c1) a pharmaceutically acceptable polymeric solubilizer; (c2) water; and (d) an antioxidant/preservative are disclosed, where the liquid softgel fill composition does not crystallize or otherwise deposit any of the active ingredients. Also disclosed are methods for the preparation of such fill compositions, and softgel capsules containing the bioavailable liquid fill composition. | 2021-10-28 |
20210330595 | NON-DIGESTIBLE CAPSULES FOR THE DELIVERY OF FLUID ABSORBING MATERIALS - The invention relates to a product, method of use, and/or method of preparing a capsule or capsular like product that comprises hydrophilic fluid-absorbing materials that bind, entrap, and/or absorb large quantities of fluid. The capsules or capsular like product may be capable of diverting the mode of fluid and waste elimination from the renal route to the gastrointestinal route. | 2021-10-28 |
20210330596 | PHARMACEUTICAL COMPOSITION FOR USE IN A COMBINATION WITH CANNABINOIDS TO ENHANCE BENEFITS OF CANNABINOIDS TO SUPPORT HUMAN ENDOCANNABINOID SYSTEM - The embodiments herein provide a pharmaceutical composition for use in a combination with cannabinoids that includes a primary essential oil, and a secondary essential oil to support the human endocannabinoid system. The primary essential oil replenishes a plurality of first micronutrients lost during the processing of cannabis. The primary essential oil contains a first therapeutically effective amount of crude cannabis essential oil. The secondary essential oil replenishes a plurality of second micronutrients lost during the processing of cannabis. The secondary essential oil contains a second therapeutically effective amount of crude cannabis essential oil. The primary essential oil and the secondary essential oil are in a liquid form. The liquid form of the primary essential oil and the secondary essential oil are respectively transformed into a powder form by performing a microencapsulation process. | 2021-10-28 |
20210330597 | Nanoparticle Depot For Controlled And Sustained Gene Delivery - One aspect of the disclosure describes a lipid conjugated cationic molecule. Other aspects of the disclosure describes nanoparticle delivery systems and methods of making the systems are disclosed. An embodiment of the nanoparticle delivery system has sustained gene delivery properties, the nanoparticle delivery system can be synthesized using biodegradable and biocompatible polymers via self-assembly. The nanoparticle delivery system comprises a plurality of nanoparticle depots, each of which has a particle-in-particle structure, and is composed of a polymeric nanoparticle, which encapsulates cationic molecule/nucleic acid complexes, facilitating enhanced retention and prolonged release of the gene payload. The polymeric nanoparticle comprises a shell, and a nanocomplex of the cationic molecule and a polynucleotide, the nanocomplexes are distributed within the shell and/or embedded in the shell. Another embodiment of the nanoparticle delivery system has one or more nanocomplexes. The one or more nanocomplexes includes a lipid conjugated cationic molecule and a polynucleotide. | 2021-10-28 |
20210330598 | Amphotericin Loaded Pegylated Lipid Nanoparticles And Methods Of Use - Compositions of nanolipid carrier molecules comprising PEG molecules and solid and liquid lipids wherein the PEG has a molecular weight of between about 1000 and 5000 are described. Methods of administering nanolipid carrier molecules are also described. Also described is a method for treating fungal ocular infections by topical ocular administration of nanolipid carrier molecules comprising PEG molecules and solid and liquid lipids wherein the PEG has a molecular weight of between about 1000 and 5000. | 2021-10-28 |
20210330599 | Nanoparticles for Controlled Release of Anti-Biofilm Agents and Methods of Use - The present invention relates to compositions and methods to treat and/or prevent biofilms and biofilm related diseases. The invention comprises a nanoparticle carrier (NPC) and at least one therapeutic agent therein. The NPC binds within biofilm and to surfaces at risk for biofilm formation and accumulation while providing local, sustained, enhanced and controlled delivery of the therapeutic agent, when triggered for release. In one embodiment, the NPC comprises pH-responsive elements that allows for specific delivery of the therapeutic agent when the local environment dictates that the agent should be delivered precisely when it is most needed. | 2021-10-28 |
20210330600 | NANOPARTICLE COMPOSITIONS FOR EFFICIENT NUCLEIC ACID DELIVERY AND METHODS OF MAKING AND USING THE SAME - Nanoparticle compositions for delivery of nucleic acids to subjects including modified dendrimers comprising cores, one or more of homogeneous or heterogeneous intermediate and terminal layers, and therapeutic or immunogenic nucleic acid agents enclosed within nanop article compositions are described. Methods for treating or preventing diseases or conditions in a subject by administering the nanoparticle compositions that provide immune responses and synergistic therapeutic or preventive effects are provided. | 2021-10-28 |
20210330601 | TRANSDERMAL THERAPEUTIC SYSTEM CONTAINING ASENAPINE - The present invention relates to transdermal therapeutic systems (TTS) for the transdermal administration of asenapine comprising a self-adhesive layer structure containing a therapeutically effective amount of asenapine, such asenapine TTS for use in a method of treatment, processes of manufacture of such TTS as well as asenapine and transdermal therapeutic systems containing asenapine for use in a method of treatment and to a method of treating a human patient by transdermal administration of asenapine. | 2021-10-28 |
20210330602 | RIVASTIGMINE PATCH FOR LONG-TERM ADMINISTRATION - The present invention relates to a patch comprising a high content of rivastigmine per unit area, which can be continuously administered for a long time. The rivastigmine patch according to the present invention is capable of continuous release of rivastigmine for a long period of time, preferably 3 days, more preferably 4 days or more after attachment, and has excellent physical and chemical stability. | 2021-10-28 |
20210330603 | METHODS OF USING CANNABINOIDS FOR INHIBITING INDUCTION OF VIRULENCE IN ENTERIC PATHOGENS - Methods of treating a subject having a gram negative bacterial infection by administering a cannabinoid such as 2-AG,CBD, the MgI inhibitor JZL184, or arachidonic acid to the subject are provided. Methods of prophylactically treating a subject at risk of developing a gram negative bacterial infection and for reducing the bacterial virulence in an infected subject are also provided. | 2021-10-28 |
20210330604 | HALOGENATED ETHER COMPOUNDS AND METHODS OF INDUCING ANESTHESIA - A method of inducing anesthesia in a subject is provided. In some embodiments, the method provides administering to the subject via the respiratory system or via injection, an effective amount of a compound or a mixture of compounds selected from the group consisting of methyl-ethyl ethers, methyl-isopropyl ethers, and methyl-propyl ethers. | 2021-10-28 |
20210330605 | ANTI-CANCER ACTIVITY OF ADAMANTANE DERIVATIVES - Provided herein are methods for treating cancer comprising administering to a subject in need thereof an adamantane derivative, or a pharmaceutically acceptable salt thereof, such as rimantadine or amantadine. In some embodiments, the adamantane derivative is PEGylated. | 2021-10-28 |
20210330606 | GLUCOSE CONSUMPTION ACCELERATOR AND GLYCOLYSIS ACCELERATOR - The present invention provides a new drug that can accelerate glucose consumption. The glucose consumption accelerator of the present invention includes: at least one selected from the group consisting of 2-amino-1-cyclohexylethanol, 1-amino-2-propanol, 1,3-bis[tris(hydroxymethyl)methylamino]propane, N-cyclohexylethanolamine, diethanolamine, diethylamine, dipropylamine, morpholine, propylamine, triethanolamine, triethylamine, and trishydroxymethylaminomethane. | 2021-10-28 |
20210330607 | BINGE BEHAVIOR REGULATORS - Methods and compositions utilizing 2-aminoindan derivatives collectively represented by Formula I as described and defined in the specification for regulating binge behavior, particularly binge drinking, are disclosed. | 2021-10-28 |
20210330608 | BINGE BEHAVIOR REGULATORS - Methods and compositions utilizing 2-aminoindan derivatives collectively represented by Formula I as described and defined in the specification for regulating binge behavior, particularly binge drinking, are disclosed. | 2021-10-28 |
20210330609 | BINGE BEHAVIOR REGULATORS - Methods and compositions utilizing 2-aminoindan derivatives collectively represented by Formula I as described and defined in the specification for regulating binge behavior, particularly binge drinking, are disclosed. | 2021-10-28 |
20210330610 | COMPOSITIONS AND METHODS FOR TREATING SEIZURE-INDUCED SUDDEN DEATH - 5-HT receptor agonists are useful in the treatment of a variety of diseases. Provided herein are methods of reducing the incidence and/or severity of seizures in a human patient using a 5-HT receptor agonist, such as, for example, a 5-HT4 agonist (e.g., fenfluramine). Methods of treating epilepsy or epileptic encephalopathy, and/or reducing, ameliorating or eliminating incidence of SUDEP in a subject diagnosed with epilepsy by administering a 5-HT4 agonist (e.g., fenfluramine) to a subject in need thereof are provided. Pharmaceutical compositions for use in practicing the subject methods are also provided. | 2021-10-28 |
20210330611 | THERAPY FOR NEUROLOGICAL DISEASES/DISORDERS - Provided herein are compositions and methods to treat or prevent neurodegeneration in a mammal, inhibit microglial activation in the CNS of a mammal, promote survival of CNS neurons in a mammal, prevent or reduce the rate of demyelination and/or neuronal injury in a mammal, promote remyelination in a mammal and/or treat or prevent or decrease oxidative stress in a mammal. | 2021-10-28 |
20210330612 | METHODS FOR TREATING CANCER RESISTANT TO CDK4/6 INHIBITORS - Disclosed herein are methods of treating a CDK4/6 inhibitor resistant estrogen receptor alpha-positive cancer in a subject having either a wild-type estrogen receptor alpha and/or a mutant estrogen receptor alpha, the method comprising administering to the subject a therapeutically effective amount of elacestrant, or a pharmaceutically acceptable salt or solvate thereof, wherein the mutant estrogen receptor alpha comprises one or more mutations selected from the group consisting of D538G, Y537X | 2021-10-28 |
20210330613 | DOSAGE FORMS AND METHODS FOR ENANTIOMERICALLY ENRICHED OR PURE BUPROPION - This disclosure relates to dosage forms containing an enantiomerically enriched or pure bupropion such as enantiomeric excess of (S)-bupropion, enantiomerically enriched (S)-bupropion, or enantiomerically pure (S)-bupropion and methods of using these dosage forms. These dosage forms may be administered to human beings in a reduced amount as compared to the amount of racemic bupropion that would be administered in the same situation. | 2021-10-28 |
20210330614 | PROCESS FOR MANUFACTURING PHENYLEPHRINE RESINATE PARTICLES; PHENYLEPHRINE RESINATE PARTICLES; AND USE OF PHENYLEPHRINE RESINATE PARTICLES IN PHARMACEUTICAL FORMULATIONS - Phenylephrine particles suitable for solid, semi solid or liquid dosage forms are disclosed. | 2021-10-28 |
20210330615 | S-ENANTIOMERICALLY ENRICHED COMPOSITIONS OF BETA BLOCKERS FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS - The present invention relates to S-enantiomerically enriched compositions of beta blockers and uses thereof, including uses of the beta blocker compositions for treating amyotrophic lateral sclerosis. The beta blocker compositions can also be used for preventing loss of lean mass, preventing body weight loss in subjects, improving quality of life in subjects, and prolonging survival in amyotrophic lateral sclerosis patients. The beta blocker can be oxprenolol or a pharmaceutically acceptable salt thereof. | 2021-10-28 |
20210330616 | AMELIORATING AGENT FOR OBESITY-RELATED METABOLIC DISEASE - An object of the present invention is to provide a drug containing, as an active ingredient, a low-molecular-weight compound that ameliorates obesity-related metabolic diseases, for example, exhibits anti-obesity action without reduction of food intake through binding to Helz2 to lower its action, on the basis of the fact that Helz2 is intensely expressed in the liver both in humans and mice, and expression levels are significantly increased in the human liver with NAFLD, as an obesity-related metabolic disease, and in fatty liver in obese mice. The present invention provides an ameliorating agent for an obesity-related metabolic disease, in particular, an ameliorating agent for fatty liver, the ameliorating agent characterized by containing guanabenz or a salt of guanabenz as an active ingredient. | 2021-10-28 |
20210330617 | METHOD FOR STABILIZING SANSHOOL COMPOUND - A method for stabilizing a sanshool compound is provided. The method for stabilizing a sanshool compound comprises a mixing step in which the sanshool compound is mixed with an antioxidant in a liquid, the liquid comprising water and/or a water-soluble organic solvent and the mixing step being conducted under the conditions of a pH of 6 or higher. | 2021-10-28 |
20210330618 | NASAL FORMULATIONS OF METOCLOPRAMIDE - Nasal formulations of metoclopramide, which remain stable and/or colorless upon storage over a period of time, are provided. Also provided are methods of treating disorders treatable with metoclopramide, comprising administering the nasal solutions to patients in need thereof. | 2021-10-28 |
20210330619 | NASAL FORMULATIONS OF METOCLOPRAMIDE - Nasal formulations of metoclopramide, which remain stable and/or colorless upon storage over a period of time, are provided. Also provided are methods of treating disorders treatable with metoclopramide, comprising administering the nasal solutions to patients in need thereof. | 2021-10-28 |
20210330620 | SCALP COOLING HAIR PRODUCT - The present invention relates generally to new and improved compositions and methods for producing reliable relief from irritation or itching of the skin of the scalp. | 2021-10-28 |
20210330621 | TREATMENT FOR INTERSTITIAL LUNG DISEASE - Methods of treating of interstitial lung disease, reducing pulmonary function decline in a subject with interstitial lung disease (ILD), and increasing forced vital capacity (FVC) in a subject suffering from ILD are provided, wherein the methods include administration of treprostinil. | 2021-10-28 |
20210330622 | VIRAL INFECTION TREATMENT WITH 5-AMINOLEVULINIC ACID - A method for amelioriation of, or prophylaxis against, a viral infection comprising administering to a patient in need of treatment a therapeutically effective amount of 5 aminolevulinic acid, optionally with at least one of cucumarin nano, zinc, vitamin C and methylene blue, and compositions thereof. Such compositions may be used for the treatment of coronavirus infections, including the SARS-CoV-2 virus, and/or rhinoviruses. | 2021-10-28 |
20210330623 | ACTIVE INGREDIENT CONSISTING OF A MIXTURE OF POLYLYSINE COMPOUNDS AND USE IN THE PREVENTION OF STROKES AND THE TREATMENT OF THE POST-STROKE INFLAMMATORY PHASE - The invention relates to an active ingredient consisting of several polylysine compounds, said polylysine compounds consisting of at least one small molecule conjugated to a polylysine, said active ingredient comprising at least the following polylysine compounds:
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