43rd week of 2017 patent applcation highlights part 11 |
Patent application number | Title | Published |
20170304466 | AAV-Based Gene Therapy - The invention relates to the field of andeno-associated virus (AAV) based gene therapy, in particular to the use of a combination of recombinant AAV-transgene vectors with an immunosuppressant and/or empty-AAV capsids. The invention further provides a composition and a kit of parts based on this combination. | 2017-10-26 |
20170304467 | BLUE DYED CHLORHEXIDINE ANTIMICROBIAL COMPOSITION FOR SKIN DISINFECTION - The present invention relates in general terms to an antimicrobial composition having chlorhexidine and a dye selected from 3,7-bis(dimethylamino)-phenothiazin-5-ium chloride and a sodium or calcium salt of [4-(α-(4-diethylaminophenyl)-5-hydroxy-2, 4-disulfophenylmethylidene)-2,5-cyclohexadien-1-ylidene] diethylammonium hydroxide usable in the medical field. In particular, the invention relates to the composition in the form of aqueous solution, hydro-alcoholic solution or gel, and its use as a coloring antiseptic and disinfectant agent, for example in pre-surgical procedures. | 2017-10-26 |
20170304468 | UPAR TARGETING PEPTIDE FOR USE IN PEROPERATIVE OPTICAL IMAGING OF INVASIVE CANCER - There is provided a novel conjugate that binds to the cell surface receptor uPA (uPAR). The conjugate is based on a fluorescence-labeled peptide useful as a diagnostic probe to the surfaces of cells expressing uPAR. The conjugate is capable of carrying a suitable detectable and imageable label that will allow qualitative detection and also quantitation of uPAR levels in vitro and in vivo. This renders the surgical resection of tumors more optimal. | 2017-10-26 |
20170304469 | ANGIOPEP AND DERIVATIVES THEREOF FOR IMAGING AMYLOIDS - The present application relates to the molecular labeling and in vivo imaging of amyloids. Specifically, the present application relates to a polypeptide-based method/vector for targeting amyloids. Such a method/vector enables the transportation of compounds or drugs across blood-brain-barrier of an individual and then binding to amyloids in brain. Particularly, the vector of the present application can transport an imaging group linked to the vector across the blood-brain-barrier, and can binds to amyloids in brain, and thus enables the labeling and imaging of amyloid deposits. When used as an imaging agent for detecting amyloid deposits in body or tissues, the vector may be labeled with suitable optical imaging groups, radioactive isotopes or imaging groups suitable for MRI or CT detection. The method/vector can especially used for the in vivo non-invasive diagnosis of amyloid-related diseases including Alzheimer's disease, and for the observation of the therapeutic effect of drugs targeting amyloid deposits. | 2017-10-26 |
20170304470 | HSP90-TARGETED INFLAMMATION AND INFECTION IMAGING AND THERAPY - The present invention provides new methods for inflammation and infection imaging and related medical applications thereof. In some embodiments, the present invention provides a method for the diagnosis of inflammation and/or infection. In some embodiments, the present invention provides a method for the treatment or prevention of inflammation and/or infection. In some embodiments, the present invention provides methods for monitoring the effect of inflammation and/or infection treatment, and/or methods for monitoring an inflammation and/or infection treatment regimen. In some embodiments, the present invention provides a method for selecting subjects for an inflammation and/or infection treatment. In some embodiments, the present invention provides a method for determining the dosage of a drug for the treatment of inflammation and/or infection. | 2017-10-26 |
20170304471 | ANTICANCER THERAPY - A subject afflicted with a cancer or precancerous condition is treated by administering an agent that increases expression of somatostatin receptors, and a cytotoxic recognition ligand. In an alternative embodiment, somatostatin analogs, which are radiolabeled are used to treat cancer or precancerous conditions. | 2017-10-26 |
20170304472 | METHOD AND APPARATUS FOR STERILIZING AND DISINFECTING AIR AND SURFACES AND PROTECTING A ZONE FROM EXTERNAL MICROBIAL CONTAMINATION - This invention relates to a method, process and apparatus for disinfecting and sterilizing all types of surfaces contaminated with microorganisms and toxic substances to render both inactive. Furthermore, this invention relates to both a method and apparatus for disinfecting and/or sterilizing breathable air and then using this air to protect a confined space from external contamination. The apparatus consists of a new ultra-violet (NUV) source that is more effective than mercury based 254 nm light for destroying DNA of virus, bacteria, spores and cists. It is most effective in breaking chemical bonds in toxic gases and Biotoxins that are useful to terrorists. It is combined with other apparatus that remove particulates and byproducts sometimes produced by the NUV source and maintains positive pressure of the confined space so as to prevent the influx of air from outside the protected zone. | 2017-10-26 |
20170304473 | UV Sterilization Of Container, Room, Space Or Defined Environment - Provided herein are portable ultraviolet (UV) devices, systems, and methods of use and manufacturing same. Methods of use include methods for UV disinfection and sterilization, more specifically, methods for UV disinfection and sterilization of a container, a room, a space or a defined environment. The portable UV devices, systems and methods are particularly useful for the UV disinfection and sterilization of a container, a room, a space or defined environment used in the food, beverage and dairy industry and in the process of fermentation for an alcoholic beverage. Provided are also portable UV devices, systems, and methods for inhibiting the growth of one or more species of microorganisms present in a container, a room, a space or a defined environment, preferably for inhibiting the growth of one or more species of microorganisms present on an interior surface of a container, a room, a space or a defined environment. | 2017-10-26 |
20170304474 | ODOR REMOVAL ASSEMBLY - An assembly for removing odors from items having a first container formed from a material that is at least partially ozone impervious and that defines a first interior that is accessible via a selectively closeable opening, an ozone generator that is adapted to generate and expel ozone gas from the ozone generator into the first interior of the first container, and a fastening mechanism for selectively maintaining the selectively closeable opening in a closed orientation in which the fastening mechanism prevents access to the first interior. In various embodiments, when the selectively closeable opening is in the closed orientation and the ozone generator expels ozone into the first interior of the first container, the ozone concentration in the first interior is at a concentration of between 1 ppm and 2000 ppm and the ozone leakage from the first container is between 0.01 ppm and 0.03 ppm of ozone. | 2017-10-26 |
20170304475 | AEROSOL DEVICE - An aerosol device having a bowl with a bottom defining a drain, and a side wall extending from the bottom to a rim. A nozzle is disposed within the bowl. The nozzle defines a chamber and an outlet orifice directed toward the side wall of the bowl. The aerosol device includes a liquid container fluidly coupled to the nozzle via a first conduit having an outlet tip disposed within the chamber of the nozzle and a second conduit connecting a source of pressurized gas to the chamber of the nozzle. The outlet tip is in the form of a tube defining elongated slots communicating from inside the tube to outside the tube, the slots each having a width defined between two parallel tube surfaces. The aerosol device generates submicron liquid droplets, and is suitable for disinfecting porous articles in an enclosed volume. | 2017-10-26 |
20170304476 | STERILIZATION DEVICE AND METHODS - Embodiments of the present disclosure generally relate to devices and methods for sterilizing equipment. More particularly, one or more embodiments described in the present disclosure are directed to portable devices for sterilizing medical equipment in emergency situations. The sterilization devices and method of the present disclosure address an unmet need for sterilizing surgical equipment in a manner that is not only effective and time-efficient, but is also portable and reliable enough to use in emergency medical situations in remote locations where modern sterilization equipment is not available. | 2017-10-26 |
20170304477 | APPARATUS AND METHOD FOR DETECTING MOISTURE IN A VACUUM CHAMBER - A method of sterilizing medical instruments using a vacuum chamber connected to reservoir by a valve in a closed state is disclosed that includes placing instruments in a non-sterile state into a sterilization pack, opening a chamber, placing the pack into the chamber, closing the chamber, withdrawing a first volume of air from the chamber, changing a volume of liquid water into vapor, opening the valve, introducing sterilant into the chamber, introducing a second volume of air into the chamber, opening the chamber, removing the pack from the chamber, and removing the instruments in a sterile-state from the pack. The process may further include the steps of repeatedly determining pressure within the chamber, calculating second-derivative values of pressure with respect to time, and determining whether any local maxima exist in a plot of second derivative values that correspond to pressures above and/or below the triple-point pressure of water. | 2017-10-26 |
20170304478 | DISINFECTANT WIPE DISPENSER - A disinfectant wipe dispenser is provided comprising a container having first and second compartments, the first compartment being dimensioned to store a supply of wipes in use; and, separated by a baffle including one or more channels communicating between the compartments. The first compartment has an outlet through which wipes may be successively drawn; and, the second compartment is dimensioned to receive one or more portions of a disinfectant composition comprising a peroxy activator, a peroxy compound and optional further excipients, selected so that addition of the dosage form to a predetermined quantity of water produces a disinfectant solution containing peracetic acid at a concentration of at least about 1000 ppm. The channels communicate between the compartments and allow flow of water and aqueous disinfectant between the compartments, and have a maximum dimension configured to prevent movement of particles of disinfectant sediment from the second compartment to the first compartment. | 2017-10-26 |
20170304479 | HOLDER FOR DISINFECTION OF TONOMETER TIPS OR THE LIKE AND METHOD OF USE - A holder device for holding a plurality of tonometer tips or the like during a disinfection procedure has a top wall, spaced rims extending downward from the top wall to engage a support surface and hold the top wall above the support surface, and handle portions extending upwards from the top wall. The top wall has a plurality of spaced holes of predetermined diameter each configured to hold a tip extending partially through the hole with a lower end of the tip spaced above a support surface. A cover plate is releasably secured between the handle portions at a location spaced above the top wall after loading the holes with tips, and holds the tips in the holes while at least a major portion of the device is submerged in a bath of disinfectant. | 2017-10-26 |
20170304480 | WASTE GAS SCRUBBING TOWER - A waste gas scrubbing tower includes a tower body unit, a filtration unit arranged in the tower body unit, a washing unit that introduces water from an external supply into the tower body unit. The tower body unit includes division boards that define a plurality of channels through which waste gas flows, the tower body unit including a waste gas inlet opening and a waste gas outlet opening. The filtration unit includes a plurality of filter members, which are arranged in the channels. The washing unit is operable to generate water mist curtains in the channels to wash the waste gas so that the waste gas that enters the waste gas scrubbing tower is subjected to multiple times of washing and filtration and purification. | 2017-10-26 |
20170304481 | Soft and Durable Nonwoven Web - A nonwoven web that contains a plurality of fibers formed from a polyolefm composition is provided. The polyolefin composition contains a rigid propylene polymer that has a relatively high melting temperature and modulus of elasticity, which can provide good strength and durability to the nonwoven web. The polyolefm composition also contains a ductile propylene polymer that has a relatively high melt flow index, which can help achieve relatively fine fibers that minimize the stiffness of the web. In addition to a rigid and ductile polymer, the polyolefin composition also contains a slip additive (e.g., fatty acid derivative). Among other things, such an additive can even further enhance the overall softness of the composition. | 2017-10-26 |
20170304482 | Porous Polyolefin Material - A polyolefin material that comprises a thermoplastic composition is provided. The composition contains a continuous phase that includes a polyolefin matrix polymer and a nanoinclusion additive dispersed within the continuous phase in the form of discrete domains. The composition further includes a beta-nucleating agent. A porous network is defined within the thermoplastic composition that includes a plurality of nanopores. | 2017-10-26 |
20170304483 | FORMULATIONS FOR WOUND THERAPY - The present invention relates to novel formulations comprising a dry powder fibrin sealant comprised of a mixture of fibrinogen and/or thrombin, for use in the treatment of wounds or injuries, in particular for use as a topical hemostatic composition or for surgical intervention. | 2017-10-26 |
20170304484 | WOUND CARE ARTICLES - Single layer and multi-layer anti-microbial wound care masks having a hydrophilic yarn containing silver and wound care articles are disclosed. | 2017-10-26 |
20170304485 | POROUS DEVICES, KITS, AND METHODS FOR DEBRIDEMENT - Porous devices are provided that include a particle-containing fibrous porous matrix and a fluid absorbed in the particle-containing porous fibrous nonwoven matrix. The particle-containing fibrous porous matrix includes a porous fibrous nonwoven matrix containing first polyolefin fibers, second polyolefin fibers including poly(ethylene), and fiberglass fibers; and microorganism-binding particles. The microorganism-binding particles are enmeshed in said porous fibrous nonwoven matrix. Methods of debridement are provided including providing a porous device including a particle-containing fibrous porous matrix and wiping a wound or an area of skin with the device; and providing a porous device including a porous fibrous nonwoven matrix and wiping a wound with the device. Further, kits are provided including a sterile package containing at least one porous device, and typically also instructions for debridement. | 2017-10-26 |
20170304486 | ABSORBENT ARTICLE COMPRISING COMPLEXED OR ENCAPSULATED REACTIVE COMPOUNDS - Absorbent articles having complexed or encapsulated reactive compounds are described herein. At least two reactive compounds are complexed or encapsulated. The reactive compounds which react with some classes of malodourant compounds and do not have unpleasant odor. | 2017-10-26 |
20170304487 | ARTIFICIAL SCAB FOR USE IN AN AIRWAY - Body tissue and structures in an airway may be treated with an artificial scab comprising an inhomogeneous, uncohesive, solid sheet-like body comprising a granular mixture of chitosan and polysaccharide particles. The artificial scab breaks apart into smaller pieces if peeled away from the surgical site or wound, thus reducing the risk of airway occlusion. | 2017-10-26 |
20170304488 | Compositions and Methods for the Prevention and/or Reduction of Scarring - The present disclosure provides methods of preventing and/or reducing scar contraction by utilizing an electrospun biocompatible scaffold. | 2017-10-26 |
20170304489 | TIME-CONTROLLED GLUCOSE RELEASING HYDROGELS AND APPLICATIONS THEREOF - The present invention relates generally to a hydrogel releasing glucose in a time-controlled manner, to medical applications thereof, and to a method for preparing said hydrogel. | 2017-10-26 |
20170304490 | ABSORBABLE DEVICE FOR BONE REGENERATION - A device for bone regeneration includes a fill element adapted to be inserted, during use, in a cavity present in a bone of a patient; the fill element being made of PGA fibers. | 2017-10-26 |
20170304491 | MATRIX FOR RESTORING SOFT TISSUE AND PRODUCING METHOD THEREFOR - Disclosed are a matrix for restoring soft tissue and a method of producing the same, the method including: forming a sheet-type absorption layer ( | 2017-10-26 |
20170304492 | POROUS COMPOSITE, BONE REGENERATION MATERIAL, AND METHOD FOR PRODUCING POROUS COMPOSITE - Provided are a porous composite containing OCP and collagen having higher compressive strength than before: a bone regeneration material containing the same: and a method for producing a porous composite. The porous composite contains octacalcium phosphate and collagen, has a pore size of 5 to 40 μm as determined by measurement using a mercury porosimeter, and contains pores of 71 to 200 μm at a rate of less than or equal to 8% in all pores of less than or equal to 200 μm. | 2017-10-26 |
20170304493 | PYROPHOSPHATE TYPE MATERIAL, PROCESS FOR PREPARING SUCH A MATERIAL AND USE FOR BONE REPAIR - A material, especially a glassy material of pyrophosphate type, corresponding to the general formula (I): {[(M | 2017-10-26 |
20170304494 | MALLEABLE DEMINERALIZED BONE COMPOSITION AND METHOD OF MANUFACTURE - A malleable demineralized bone composition consists of cortical bone made from a first portion and a second portion. The first portion of cortical bone is made from cut pieces freeze dried then ground into particles and demineralized then freeze-dried. The second portion of cortical bone is shaved into shavings. The shavings are long thin strips subjected to freeze-drying. The freeze-dried shavings are ground and demineralized and then freeze-dried. A volume of the second portion is placed in a solution of sterile water to create a mixture, the water volume being twice the second portion, the mixture is autoclaved under heat and pressure to form a gelatin, and the first portion is mixed with the gelatin to form a malleable putty or paste. | 2017-10-26 |
20170304495 | BONE GEL SHEET COMPOSITION AND METHOD OF MANUFACTURE - A bone gel composition consists of cortical bone. The cortical bone is made from cut pieces freeze-dried then ground into particles and demineralized then freeze-dried. A volume of the particles is placed in a solution of sterile water to create a mixture, the water volume being at least twice the particle volume, the mixture is autoclaved under heat and pressure to form a gelatin, the resulting bone gel is formed into sheets having a thickness (t). | 2017-10-26 |
20170304496 | POLYURETHANES FOR OSTEOIMPLANTS - Biological-based polyurethanes and methods of making the same. The polyurethanes are formed by reacting a biodegradable polyisocyanate (such as lysine diisocyanate) with an optionally hydroxylated biomolecule to form polyurethane. The polymers formed may be combined with ceramic and/or bone particles to form a composite, which may be used as an osteoimplant. | 2017-10-26 |
20170304497 | METHODS FOR INHIBITING STENOSIS, OBSTRUCTION, OR CALCIFICATION OF A STENTED HEART VALVE OR BIOPROSTHESIS - Methods for inhibiting stenosis, obstruction and/or calcification of a heart valve following implantation in a vessel having a wall are disclosed. In one aspect the method includes providing a bioprosthetic heart valve mounted on an elastical stent; treating the bioprosthetic heart valve with a tissue fixative; coating the stent and the bioprosthetic valve with a coating composition including one or more therapeutic agents; implanting the bioprosthetic valve into the vessel in a diseased natural valve site; eluting the coating composition from the bioprosthetic valve; and inhibiting stenosis, obstruction and/or calcification of the bioprosthetic heart valve by preventing the attachment of stem cells to the bioprosthetic heart valve, the stem cells circulating external and proximate to the bioprosthetic heart valve by activating nitric oxide production (i) in the circulating stem cells, (ii) in an endothelial cell lining covering the bioprosthetic heart valve tissue, (iii) or both. | 2017-10-26 |
20170304498 | COCOON-BASED VASCULAR PATCH AND MANUFACTURING METHOD THEREOF - Disclosed herein are a cocoon-based, vascular patch and a method for manufacturing the same. The cocoon-based, vascular patch is manufactured by dividing a cocoon into two or more fragments in a predetermined form, the cocoon having a shell having a predetermined thickness. The cocoon-based vascular patch can be relatively simply manufactured in a more cost efficient manner than conventional vascular patches, and has excellent cell growth potential and biocompatibility. | 2017-10-26 |
20170304499 | INJECTABLE PERIPHERAL NERVE SPECIFIC HYDROGEL - The present invention relates to a peripheral nerve-specific hydrogel material, which is deliverable in a minimally invasive fashion, sustains the growth of neurons, and speeds recovery following surgical reconstruction. | 2017-10-26 |
20170304500 | MICROFABRICATED TISSUE SCAFFOLDS AND METHODS OF MAKING AND USING THE SAME - The present description relates to the discovery of materials, devices, systems and methods for microfabrication of engineered tissue scaffolds for the growth and culture of biological tissues for tissue repair, transplantation, disease treatment, regenerative medicine, drug testing or combinations thereof. The engineered tissue scaffolds mimic native conditions and structures, including, e.g., native physiology, tissue architecture, vasculature, and other properties of native tissues. | 2017-10-26 |
20170304501 | METHOD FOR TREATING A MEDICAL IMPLANT - A method for treating a medical implant uses plasma polymerization to apply a coating At least one treatment parameter is selected so that the reactive chemical groups of the coating are chemically modified to prevent an adsorption of interfering substances into the coating. An implant includes a plasma polymer coating that is biocompatible, and includes a antibiotically acting metal. The coating is free from aldehyde groups | 2017-10-26 |
20170304502 | OSTEOIMPLANT COMPRISING AN INSOLUBLE FIBROUS POLYMER - Methods for making an osteoimplant are provided. In one embodiment the method includes applying a mechanical force to an aqueous slurry of insoluble collagen fibers to entangle the insoluble collagen fibers so as to form a semi-solid mass of entangled insoluble collagen fibers; and lyophilizing the semi-solid mass of entangled collagen fibers to form the osteoimplant. An osteoimplant containing entangled insoluble collagen fibers is also provided. | 2017-10-26 |
20170304503 | TUBULAR STRUCTURE, DEVICE FOR MANUFACTURING TUBULAR STRUCTURE, AND METHOD FOR MANUFACTURING TUBULAR STRUCTURE - An object of the present invention is to provide a cell-containing bioabsorbable tubular structure having molecular permeability, a device for manufacturing the tubular structure, and a method for manufacturing the tubular structure. According to the present invention, there is provided a tubular structure constituted with a cell structure which contains biocompatible polymer blocks and cells, in which the plurality of polymer blocks is disposed in voids between the plurality of cells. | 2017-10-26 |
20170304504 | METHOD FOR PRODUCING THE LAMINATE OF A SHEET-SHAPED CELL CULTURE AND FIBRIN GELS - A method for treating a disease associated with tissue abnormality in a subject. The method includes administering an amount of a pharmaceutical composition to a subject in need of treating a disease associated with tissue abnormality, the pharmaceutical composition comprising a laminate comprising a fibrin gel and a cell culture. The laminate is produced by a method, which includes forming a fibrin gel layer on an upper surface of the cell culture by a reaction between fibrinogen and thrombin, wherein: the cell culture is prepared on a culture dish and the laminate of the fibrin gel and the cell culture are transferred onto a subject's heart. The laminate further includes a reinforcing portion made of a fibrin gel, the reinforcing portion formed by laminating the fibrin gel on the fibrin gel layer of the laminate of the cell culture and the fibrin gel. | 2017-10-26 |
20170304505 | POLYTETRAFLUOROETHYLENE TUBE - A polytetrafluoroethylene tube is provided and has a thickness of 0.1 mm or less, a tensile elongation at break of 350% or more, and a melting energy of 0.6 J/g or more which is calculated from an endothermic peak at 370° C.±5° C. in a procedure of increasing a temperature in differential scanning calorimetry (DSC). | 2017-10-26 |
20170304506 | LUBRICIOUS MEDICAL DEVICE COATING WITH LOW PARTICULATES - Embodiments of the invention include lubricious medical device coatings. In an embodiment the invention includes a coating for a medical device including a first layer comprising polyvinylpyrrolidone derivatized with a photoreactive group; and a first cross-linking agent comprising at least two photoreactive groups; a second layer disposed on the first layer comprising polyvinylpyrrolidone derivatized with a photoreactive group; a second cross-linking agent comprising at least two photoreactive groups; and a polymer comprising polyacrylamide, the polymer derivatized with at least one photoreactive group. Other embodiments are included herein. | 2017-10-26 |
20170304507 | Extracellular Matrix Sheet Structures - A sheet structure formed from an extracellular matrix (ECM) composition that includes acellular ECM derived from small intestine submucosa (SIS) tissue, gentamicin and vancomycin. The sheet structure is configured to modulate inflammation of damaged biological tissue and induce cell and tissue proliferation, bioremodeling of the damaged biological tissue, and regeneration of new tissue and tissue structures with site-specific structural and functional properties, when the tissue structure is delivered to the damaged biological tissue. | 2017-10-26 |
20170304508 | THORACIC CATHETER DEVICE - A thoracic catheter system comprises a flexible thoracic catheter for inserting into a thoracic cavity of a human. A distal end of the thoracic catheter has a plurality of apertures. A proximate end of the thoracic catheter is designed to extend out of the thoracic cavity. A three way valve is one of fused with and removablely attached to the proximal end of the thoracic catheter. | 2017-10-26 |
20170304509 | PRESSURE CONTROL DURING PROCESSING OF ADIPOSE TISSUE - An adipose tissue (AT) transfer system includes, on the aspiration side, an aspiration cannula, an aspiration pump, a container, and flexible tubing connecting the aspiration cannula to the container. On the reinjection side, the system includes a reinjection cannula, flexible tubing connecting the inlet of the reinjection cannula to the container, and a reinjection pump imposing positive-displacement pumping action on the flexible tubing and causing movement of AT in a continuous or pulsed mode. The aspiration pump operates to continually supply harvested AT to the second flexible tubing while the reinjection pumps causes continuous or pulsed deposition of the AT at the injection site. To ensure that internal pressure and/or flow of the AT through a channel of delivery of the AT to the reinjection site does not exceed a predetermined value, the system contains an external pressure sensor configured to measure such internal pressure in absence of a part that is in direct contact with the AT. | 2017-10-26 |
20170304510 | REDUCED PRESSURE APPARATUS AND METHODS - Some embodiments have a pump assembly mounted to or supported by a dressing for reduced pressure wound therapy. The dressing can have visual pressure, saturation, and/or temperature sensors to provide a visual indication of the level of pressure, saturation, and/or temperature within the dressing. Additionally, the pump assembly can have a pressure sensor in communication with the flow pathway through the pump, and at least one switch or button supported by the housing, the at least one switch or button being accessible to a user and being in communication with the controller. The pump assembly can have a controller supported within or by the housing, the controller being configured to control an operation of the pump. The pump can be configured to be sterilized following the assembly of the pump such that all of the components of the pump have been sterilized. | 2017-10-26 |
20170304511 | FLUID COLLECTION SYSTEMS AND METHODS OF USE - Fluid collection systems and methods are disclosed which may utilize suction to draw fluids into containers for storage and eventual disposal. The system may utilize rigid or semi-rigid canisters to provide a chamber in which fluids may be collected under negative pressure, stored, and transported. The system may utilize disposable or reusable flexible, semi-rigid, or rigid liners for isolating fluid and liquid waste from the walls of the canister. In various embodiments, either a single canister assembly or multiple canister assemblies are mounted to a manifold, the manifold being configured to support each canister assembly and/or provide a connection to a source of suction for each canister assembly. | 2017-10-26 |
20170304512 | Methods And Devices For Applying Closed Incision Negative Pressure Wound Therapy - A surgical tissue therapy device includes a sealant layer and a collection chamber. The sealant layer functions so as to create a sealed enclosure, or space between it and the surface of a patient, by forming an airtight seal around a surgical area of skin trauma. The closed incision tissue therapy device also comprises a collection chamber, which may comprise an elongate tubular chamber with a plurality of longitudinally spaced openings. The collection chamber may be configured to be in fluid communication with the sealant layer and the area of skin trauma and functions as to distribute the negative pressure applied to a surgically closed area of skin trauma. Preferably, the pressure under the sealant layer is reduced by expanding the volume of the enclosure space and thereby decreasing the density of air molecules under the sealant layer. The collection material may comprise a material and/or a configuration that permits length changes based upon the length of the corresponding surgical wound or incision. | 2017-10-26 |
20170304513 | METHODS AND SYSTEMS FOR REDUCING THE RISK OF BACTERIAL CONTAMINATION IN COLLECTED PLATELETS - Methods and systems for reducing bacterial contamination of platelets are disclosed. The methods and systems disclosed herein provide for the processing of a pre-determined volume of whole blood so as to reduce the risk that platelets separated and collected from the whole blood have a reduced risk of bacterial contamination. | 2017-10-26 |
20170304514 | GUIDEWIRE SYSTEM AND METHOD OF PUMP INSTALLATION USING SAME - In one embodiment, the present invention is a method of positioning in a mammalian heart of a patient a blood pump including an inflow cannula, a pump housing and an outflow cannula, the method including forming an incision in a low-pressure location on the heart wall; passing the outflow cannula of the blood pump through the incision and into a left ventricle of a heart; positioning a tip of a guidewire into an aorta, distal to an aortic valve; advancing the tip through the aortic valve and into the left ventricle; connecting the tip to the outflow cannula; pulling the blood pump with the guidewire to advance at least a portion of the outflow cannula through the aortic valve and into the aorta; securing the blood pump to the heart, the aorta, or both; disconnecting the tip from the blood pump; and removing the guidewire from the patient. | 2017-10-26 |
20170304515 | THORACIC AORTA VENTRICULAR ASSIST SYSTEM - An implantable heart assist system includes a compressible pumping chamber including an inlet conduit configured to be placed in fluid connection with the descending thoracic aorta and an outlet conduit configured to be placed in fluid connection with the thoracic aorta; and a pump system comprising a first rigid member, a second rigid member spaced from the first rigid member so that at least a portion of the pumping chamber may be positioned between the first rigid member and the second rigid member, a drive system configured to cause the second rigid member to move toward the first rigid member or away from the first rigid member, and a controller in operative connection with the drive system and controlling the motor, wherein movement of the second rigid member toward the first rigid member results in compression of the pumping chamber and movement of the second rigid member away from the first rigid member causes expansion of the pumping chamber. | 2017-10-26 |
20170304516 | DIALYSATE POTASSIUM CONTROL DURING A DIALYSIS SESSION - The present invention relates to devices, systems, and methods for controlling the concentration of potassium in dialysate in a closed loop potassium control system. The devices, systems, and methods can be compatible with any dialysis system including sorbent-based dialysis systems, single pass dialysis systems, or other multi-pass dialysis systems. The systems can use closed loop potassium control over potassium concentration in the dialysate to reduce the probability of patient arrhythmias. The potassium concentration can be controlled and personalized to a patient using certain predetermined patient parameters. Related systems, algorithms, and control systems are contemplated for optimizing the potassium concentration in the dialysate. | 2017-10-26 |
20170304517 | Blood Purification Device - In a blood purification device containing a blood purifier, a blood circuit, a blood pump, and a dialysate line having a fresh dialysate supply line and a used dialysate discharge line, a pair of plunger pumps are disposed in the dialysate line. The pair of plunger pumps are synchronized so that delivery of a fresh dialysate from one plunger pump and suction of a used dialysate into the other plunger pump simultaneously occur and the stroke of at least one of the pair of plunger pumps is made variable. | 2017-10-26 |
20170304518 | DEVICE FOR EXTRACORPOREAL BLOOD TREATMENT INVOLVING A CHANGE OF CONCENTRATE - A device for extracorporeal blood treatment comprising at least a first concentrate connection which is set up to feed at least a first concentrate into the device for extracorporeal blood treatment as the basis for generating a dialysate; at least a second concentrate connection which is configured to feed at least a second concentrate into the device for extracorporeal blood treatment as the basis for generating a dialysate; wherein the device for extracorporeal blood treatment is configured to switch over from supplying the at least first concentrate to supplying the at least second concentrate at a predetermined time or after a predetermined period of time during an ongoing blood treatment. | 2017-10-26 |
20170304519 | Method And Device For Supplying Dialysis Liquid To A Dialysis Apparatus - The invention relates to a method and to a device for supplying a dialysis device with dialysate, and to a dialysis device comprising a device for supplying the dialysis device with dialysate. For producing dialysate, a container | 2017-10-26 |
20170304520 | SYSTEM AND METHOD FOR DELIVERING A TARGET VOLUME OF FLUID - A method for delivering a target volume of fluid to a destination is provided. The method includes delivering a first volume of fluid to the destination in increments each having approximately a first incremental volume, the first volume of fluid being less than the target volume and delivering a second volume of fluid to the destination in increments each having approximately a second incremental volume, the second incremental volume being less than the first incremental volume, such that the sum of the first volume and the second volume is approximately equal to the target volume. | 2017-10-26 |
20170304521 | CLOSED-CIRCUIT DEVICE AND METHODS FOR ISOLATION, MODIFICATION, AND READMINISTRATION OF SPECIFIC CONSTITUENTS FROM A BIOLOGICAL FLUID SOURCE - The present invention relates to a method and apparatus for the isolation, modification and re-administration of a molecule or biomolecule, or a class of biomolecules, from the body fluid of a mammal via an extracorporeal closed circuit device. The device is able to capture and modify the biomolecule by the covalent or non-covalent attachment of a secondary molecule or protein, by cross-linking the captured molecule, or by altering the structure of the molecule (for example, by deglycosylation, peptide cleavage, or aggregation). The apparatus can be used to return the modified molecule or biomolecule to the mammalian subject. The device and methods may be utilized for the patient-specific diagnosis and/or treatment of a disease state which presents an associated molecule or protein in plasma or any other fluidized physiological system. | 2017-10-26 |
20170304522 | Method and Apparatuses for Preparing an Extracorporeal Blood Circuit for the Treatment of Blood - The present disclosure concerns a method for preparing an extracorporeal blood circuit for its use in a blood treatment of a patient, which treatment is carried out using a blood treatment apparatus and using a blood treatment device, which comprises a blood chamber and a dialysate chamber partitioned off therefrom by a membrane, The method comprising: filling the extracorporeal blood circuit using a priming solution, wherein the priming solution comprises citrate, or filling of the extracorporeal blood circuit using a priming solution and using a citrate solution. The invention further comprises devices suitable for carrying out the method. | 2017-10-26 |
20170304523 | Cardioplegic Agent Delivery System - A cardioplegic agent delivery system comprises a syringe pump for providing cardioplegic agent into a carrier fluid of a perfusion system, a flow sensor for sensing a flow of the carrier fluid, and an interlock responsive to the flow sensor. The interlock prevents operation of the syringe pump in the absence of carrier fluid flow sensed by the flow sensor. This provides increased safety in a cardioplegic agent delivery system. | 2017-10-26 |
20170304524 | Therapeutic Compositions for Viral-Associated Disease States and Methods of Making and Using Same - A method comprising obtaining a bodily fluid from a subject; contacting the bodily fluid with an adsorbent material comprising a synthetic carbon particle (SCP) to produce a first filtrate having a level of disease mediators (y); contacting the first filtrate with an adsorbent material comprising the SCP and an anion exchange resin where the ratio of SCP to anion exchange resin is from about 0.1:100 to 100:0.1 to produce a second filtrate; contacting the second filtrate with an adsorbent material comprising the SCP and a cation exchange resin where the ratio of SCP to cation exchange resin is from about 1:100 to produce a third filtrate; and administering the third filtrate to the subject. | 2017-10-26 |
20170304525 | SYSTEM AND METHOD FOR PROVIDING AN INJECTION - A system for preparing an injection includes a first container with a first cavity and a rigid outer wall and two ends, a movable stopper being provided on one side of the first cavity, which sealingly closes this cavity and is displaceable inside the first container and comprising a second container, which encloses a second cavity, one container comprising a first substance, and the other container comprising a second substance. The second container comprises an at least regionally elastic wall and in this way has a variable volume. The second container is designed such that a pressure can be built inside the second container by way of the at least regionally elastic wall. The second container is a tube. | 2017-10-26 |
20170304526 | CLEANING INSTRUMENT FOR LARGE INTESTINE - Disclosed is a colonic irrigator capable of cleansing the inside of the large intestine and removing impacted feces remaining inside the large intestine by spraying a cleansing solution into the large intestine. The colonic irrigator includes a cleansing body | 2017-10-26 |
20170304527 | WOUND IRRIGATION SYSTEM - This document provides devices, systems, and methods for treating patients with wounds. For example, this document provides a multi-lumen tubular device that can deliver wound irrigation, wound suction, and medicinal treatment through the lumens of the tubular device. | 2017-10-26 |
20170304528 | IMPLANTABLE MEDICAL DEVICE FOR DELIVERING CELLS - An implantable and retrievable medical device is provided. The device may be implanted in and extracted from a patient and the device is adapted to house and deliver donor cells or other drugs. The device comprises a hollow core having a volume for receiving cells and a plurality of layers surrounding the core. The layers comprise various materials suitable for enhancing immunoprotection and for promoting vascular growth into the device. | 2017-10-26 |
20170304529 | SELF-ORIENTING SYRINGE AND SYRINGE INTERFACE - A medical injector including at least one syringe port for engaging at least one syringe and having a locking mechanism. The locking mechanism enables the syringe to self-align with the syringe port for locking engagement upon insertion of the syringe into the syringe port and to axially eject the syringe from the port upon rotational disengagement of the syringe from the port. | 2017-10-26 |
20170304530 | INFUSION PREPARATION - An object of the present invention is to provide an infusion preparation in which the Maillard reaction between an amino acid and a reducing sugar does not occur during storage and the size of fat particles in the fat emulsion does not increase during storage, and in which various types of vitamins can be incorporated in a stable manner, in spite of the fact that it is a two-chamber infusion preparation. Furthermore, even if only one of the infusions (of the infusion preparation) is administered, the patient is unlikely to develop hyperkalemia, vascular pain, or phlebitis. The present invention provides an infusion preparation containing two chambers separated by a partition that can be communicably opened, wherein a first chamber contains a first-chamber infusion containing a sugar and a fat emulsion, a second chamber contains a second-chamber infusion containing an amino acid and an electrolyte, the first-chamber infusion is substantially free of potassium, and has a relative osmotic pressure of 2.0 to 3.0, the second-chamber infusion has a potassium concentration of 40 mEq/L or less and a relative osmotic pressure of 2.5 to 3.5, and a mixture of the first- and second-chamber infusions has a potassium concentration of 16 mEq/L or more as measured upon communicably opening the partition. | 2017-10-26 |
20170304531 | DEVICE FOR CONNECTING A VIAL TO A CONTAINER OR TO A FLUID LINE AND TRANSFERRING THE CONTENTS OF A VIAL TO A CONTAINER OR A FLUID LINE AS WELL AS A METHOD FOR DOING SO AND USE OF SUCH A DEVICE - The invention relates to a device and a method for connecting a vial [ | 2017-10-26 |
20170304532 | FLUID-CONNECTION MECHANISM AND METHODS FOR PATCH-PUMPS - Embodiments may include a method of delivering a drug. The method may include removing or releasing a structure from a patch-pump assembly. The patch-pump assembly may include a sealed prefilled drug-reservoir, a fluid passageway, a cannula-containing assembly, and a penetrator. The method may also include penetrating the sealed prefilled drug-reservoir containing the drug to establish fluid communication between the sealed prefilled drug-reservoir and a fluid passageway by removing or releasing the structure. The method may further include flowing the drug from the prefilled drug-reservoir to the fluid passageway. In addition, the method may include flowing the drug from the fluid passageway to a cannula-containing assembly. Furthermore, the method may include delivering the drug subcutaneously to a subject using the cannula-containing assembly. | 2017-10-26 |
20170304533 | IMPLANTABLE MEDICAL DEVICE FOR MINIMALLY-INVASIVE INSERTION - In one aspect, containment devices are provided that include a microchip element having one or more containment reservoirs that are configured to be electrically activated to open; an electronic printed circuit board (PCB) or a silicon substrate positioned adjacent to the microchip element; one or more electronic components associated with the microchip element or the PCB/silicon substrate; and a first inductive coupling device associated with the microchip element or the PCB/silicon substrate, wherein the first inductive coupling device is in operable communication with the one or more electronic components. In another aspect, implantable drug delivery devices are provided that include a body housing at least one drug payload for actively controlled release, wherein the ratio of the volume of the at least one drug payload to the total volume of the implantable drug delivery device is from about 75 μL/cc to about 150 μL/cc. | 2017-10-26 |
20170304534 | THERAPY SYSTEM INCLUDING MULTIPLE POSTURE SENSORS - Posture-responsive therapy is delivered by the medical system based on posture state input from only one of multiple posture sensors at any given time. An example implantable medical system includes a first posture sensor and a second sensor. A processor controls therapy delivery to the patient based on at least one of a patient posture state or a patient activity level determined based on input from only one of the first or second posture sensors. In some examples, one of multiple posture sensors of an implantable posture-responsive medical system is used to automatically reorient another posture sensor (of the system), which has become disoriented. The disoriented posture sensor may be automatically reoriented for one or more posture states at a time. | 2017-10-26 |
20170304535 | DROPPING RATE MEASURING DEVICE, DROPPING RATE CONTROLLER, DRIP INFUSION DEVICE, AND LIQUID DROPLET VOLUME MEASURING DEVICE - A dropping rate measuring device for measuring a flow rate of liquid droplets which grow on a lower end of a nozzle and intermittently drop from the lower end of the nozzle includes an imaging unit that images a growing liquid droplet which is growing on the lower end of the nozzle at a plurality of time points and acquires a plurality of pieces of image data of the growing liquid droplet, and a data processor that calculates the flow rate by analyzing the plurality of pieces of image data acquired by the imaging unit. | 2017-10-26 |
20170304536 | CANNULATED DOSE DELIVERY DEVICE, SYSTEM AND METHOD OF USE - The present subject matter includes a cannulated delivery device made of an adapter configured to connect to a syringe; a delivery device tip configured to connect to a dosing chamber; an internal chamber of the cannulated delivery device connecting the adapter and to the delivery device tip, and the internal chamber defining a dose pathway and a system and method of use of the device to increase dosage delivery to a patient while maintaining a sterile fluid pathway. | 2017-10-26 |
20170304537 | DRIVE MECHANISM OF AN INJECTION DEVICE - A drive mechanism of an injection device for setting and dispensing of a dose of a medicament includes a body accommodating a cartridge filled with a medicament, an insert axially displaceable inside the body between a proximal operating position and a distal reset position, a piston rod to operably engage with a piston of the cartridge, a drive sleeve rotationally coupled with the piston rod and is rotationally lockable to the body for setting of a dose and rotationally releasable from the body for dispensing of a dose, respectively. The drive sleeve is axially displaceable relative to the body from a proximal operating position into a distal reset position through an axial connection of the insert and the drive sleeve, where the drive sleeve is rotationally released from the body when in the distal reset position. | 2017-10-26 |
20170304538 | MEDICAMENT DELIVERY DEVICE - A medicament delivery device is presented having a housing that is arranged to accommodate a medicament container, a drive mechanism capable of, upon activation, act on said medicament container, a communication unit arranged in the housing, a switch operably connectable to the drive mechanism and connected to the communication unit for activating the communication unit when the switch is operated, wherein the switch is operated by the drive mechanism at the end of a dose delivery sequence. | 2017-10-26 |
20170304539 | AUTOMATIC ADMINISTRATION INSTRUMENT FOR MEDICAL USE - An automatic administration instrument includes a syringe and a partition wall in the syringe which partitions the syringe into different rooms for respectively holding plural kinds of drug solutions or a drug and a drug solution. A partition-wall driver displaces the partition wall and an injection needle is connected to the syringe. A body cap attached to the administration instrument body so as to cover the injection needle. The syringe, the partition wall, and the body cap are configured such that displacing the partition wall dissolves or mixes the drug solutions or the drug and the drug solution in a state that the injection needle is covered by the body cap. | 2017-10-26 |
20170304540 | INJECTION DEVICE CONFIGURED TO MATE WITH A MOBILE DEVICE - Methods for operating an injection device that is mated to a mobile device are disclosed. Methods include sensing movements of the injection device and enabling inputs on the mobile device based on the movements of the injection device. Methods also include receiving desired injection parameter values into the mobile device, transmitting signals indicative of injection parameters from the mobile device to the injection device, activating injection of medicament with the injection device in accordance with the signals received from the mobile device, and obtaining data regarding the administered injection from the injection device. | 2017-10-26 |
20170304541 | Medicament Delivery Device - The present invention relates to a medicament delivery device comprising a housing ( | 2017-10-26 |
20170304542 | ACTIVATING MECHANISM FOR A MEDICAMENT DELIVERY DEVICE AND MEDICAMENT DELIVERY DEVICE - The invention relates to an activating mechanism for a medicament delivery device ( | 2017-10-26 |
20170304543 | NEEDLE-FREE INTRADERMAL INJECTION DEVICE - A needle-free injection device suitable for delivering a therapeutic substance into the intradermal space of a patient. The needle-free injection device includes an injector body defining a syringe end. The device also includes a first handle attached with a hinge to the injector body such that the first handle pivots between an open and a closed position and remains attached to the injector body during an injection, a main spring positioned within the injector body, a return sleeve engaged with the main spring, and a first linkage between the first handle and the return sleeve. The first linkage causes the return sleeve to move away from the syringe end of the injector body when the first handle is moved from the open position to the closed position, thereby compressing the main spring. Needle-free injection systems and methods of operating a needle-free injection device are also disclosed. | 2017-10-26 |
20170304544 | NEEDLELESS SYRINGE - A needleless syringe comprises a main syringe body which is a main body thereof and which has, in the main body, a sliding movement passage connected to an opening provided on a front end surface of the main body; a holding unit which has an accommodating unit for accommodating an injection objective substance so that the injection objective substance is releasable; and a driver that is configured to apply energy to the holding unit in order to allow the holding unit to slide toward the opening. When the energy is applied by the driver to the holding unit disposed at the initial position, the holding unit slides in the sliding movement passage to abut against the opening at the abutment position, and thus the injection objective substance accommodated in the accommodating unit is discharged via the opening. Accordingly, the high injection performance of the needleless syringe is appropriately exhibited. | 2017-10-26 |
20170304545 | APPARATUS FOR DETERMINING INFORMATION ASSOCIATED WITH REFLECTION CHARACTERISTICS OF A SURFACE - Apparatus for determining information associated with reflection characteristics of a surface comprising a sensor ( | 2017-10-26 |
20170304546 | APPARATUS FOR DETERMINING INFORMATION ASSOCIATED WITH REFLECTION CHARACTERISTICS OF A SURFACE - Apparatus comprising: a sensor configured to generate sensor output dependent on an intensity of light incident on the sensor and having a field of view directed at an external surface in use; an illumination source configured to emit light onto the external surface in use; a window located such as to allow light to pass from the illumination source to the external surface and to allow light to pass to the sensor from the external surface in use; a shield coupled to or integral with the window, the shield being substantially opaque to substantially all wavelengths of light detectable by the sensor and defining an aperture which limits the field of view of the sensor; and a processor configured to use the sensor output to determine information associated with reflection characteristics of the external surface. | 2017-10-26 |
20170304547 | MEDICAL CONNECTOR WITH INTERNAL VALVE MEMBER MOVABLE WITHIN MALE LUER PROJECTION - Disclosed herein is a valve assembly comprising a male luer end portion and a female luer end portion and a passage for the transfer of fluids extending between the male and female luer end portions, valve means movable between a first position, in which the passage is closed, and a second position, in which the passage is open, biasing means for biasing the valve means toward the first position, and actuating means extending into the male luer end portion and coupled to the valve means to actuate the valve means when a female luer end portion of a medical accessory is engaged with the male luer end portion. | 2017-10-26 |
20170304548 | A Power Pack Assembly for a Medicament Delivery Device - A power pack assembly for a medicament delivery device, the power pack comprising a plunger rod ( | 2017-10-26 |
20170304549 | A SUPPLEMENTARY DEVICE FOR ATTACHMENT TO A DRUG INJECTION DEVICE FOR MONITORING INJECTION DOSES HAVING OCR IMAGING SYSTEM WITH GLARE REDUCTION - The subject matter described herein relates to a supplementary device for attachment to an injection device, the supplementary device comprising: a first imaging arrangement and a second imaging arrangement each configured to capture an image of a moveable number sleeve of the injection device from different respective angles. The supplementary device also comprises a plurality of light sources and a processor arrangement configured to control operation of the first imaging arrangement and the second imaging arrangement and the plurality of light sources and to receive image data from each of the imaging arrangements, wherein the processor arrangement is configured to combine images captured by the first imaging arrangement and the second imaging arrangement into a single image. | 2017-10-26 |
20170304550 | DOSING ASSEMBLY FOR DRUG DELIVERY DEVICE WITH DIFFERENT LEADS AND MULTI-START THREAD SECTION - The present invention is generally directed to an assembly for a drug delivery device comprising a first threaded member ( | 2017-10-26 |
20170304551 | DRUG INJECTION DEVICE WITH RESETTABLE MECHANISM ALLOWING PISTON ROD RETRACTION UPON DRUG CARTRIDGE CHANGE - A drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing, a dose setting element rotatable relative to the housing during dose setting and dose dispensing, a drive member coupled to the dose setting member via a clutch, and a piston rod coupled to the housing and to the drive member. Further, the device further comprises a cartridge holder removably attached to the housing and a reset element, which is axially constrained to the dose setting element, and at least one spring acting on the reset element, such that, if the cartridge holder is detached from the housing, the reset element is axially moved relative to the housing onto a position in which the dose setting element is rotationally constrained to the housing and the drive member is allowed to rotate relative to the housing. | 2017-10-26 |
20170304552 | A DRUG DELIVERY DEVICE WITH AT LEAST ONE TRANSPARENT REGION OF HOUSING - The present disclosure relates to a drug delivery device comprising: a housing; a moveable number sleeve disposed within the housing and having numbers printed thereon; and a transparent window occupying an aperture of the housing and covering the number sleeve such that the number sleeve is visible through the transparent window. At least one region of the housing located adjacent to the transparent window is transparent to visible light and is in optical communication with the transparent window. | 2017-10-26 |
20170304553 | SINGLE SLIDER DOUBLE BARREL SYRINGE AND METHOD TO USE SAME FOR MEDICAL DIAGNOSTICS, THERAPEUTIC USE, AND PLACEMENT CONFIRMATION AND JOINT SPACE INJECTION - A syringe is provided having a hub with an orifice, first and second barrels having interior surfaces to form respective lumens, a slider, and an optional test indicator. The first and second barrels slideably receive respective first and second plungers for movement therein. The slider is operable to provide a fluidly communicative path between the orifice of the hub and the first and second barrel lumens. The optional test indicator is responsive to at least one characteristic of bodily fluid, the test indicator positioned to be exposed to any bodily fluid drawn into the first barrel lumen and visible from an exterior of the first barrel. | 2017-10-26 |
20170304554 | Insert and Drug Delivery Device Herewith - The present disclosure is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament and to an insert for such a device. The insert comprises a cup-shaped body with a distal end and a proximal end. The body has a sidewall and a tube which extends centrally through the cup-shaped body in a longitudinal direction, thereby defining an annular space between the sidewall and the tube. The annular space is open in the proximal direction for receiving a compression spring. The tube comprises a thread provided at an inner surface of the tube. Further, the tube, the sidewall and/or a second part comprise a clutch feature for rotationally constraining a component part to the insert. | 2017-10-26 |
20170304555 | EPIDURAL NEEDLE ASSEMBLY - An epidural needle assembly including an epidural needle assembly and an injection needle assembly. The injection needle assembly is slidably mounted on the needle of the epidural needle assembly between extended and retracted positions. The injection needle assembly includes an injection hub having an injection needle secured thereto which extends forwardly therefrom. When the injection needle assembly is in its retracted position, the forward end of the injection needle is positioned rearwardly of the forward end of the epidural needle. When the injection needle assembly is in its extended position, the forward end of the injection needle is positioned forwardly of the forward end of the epidural needle. When in its extended position, the injection needle is able to create a hole in the skin of a person or animal to permit the epidural needle to be inserted therein. | 2017-10-26 |
20170304556 | Needle Cover Assembly - The present invention relates to a needle cover assembly to be used with a medicament delivery device, wherein said needle cover assembly ( | 2017-10-26 |
20170304557 | VACCINATION DELIVERY SYSTEM AND METHOD - A device can be used for delivering a dose of a vaccine, medicine, medication, drug, or prescription. For example, this document describes a wearable vaccination device that plays an audible sound or musical tune for distracting or entertaining the patient while an intradermal vaccine is delivered via the patient's skin. The control portion of the wearable vaccination device includes a processing unit, a rhythm producer that produces audible sounds to distract or entertain the patient, and an injection module that provides an intradermal injection using one or more microneedles. | 2017-10-26 |
20170304558 | APPLICATOR FOR CRYOANESTHESIA AND ANALGESIA - A handheld cryoanesthesia or analgesia device for cooling a target area on cutaneous membranes, mucous membranes, and tissue of the mucocutaneous zone having an elongated body and a thermoelectric cooling system disposed within the elongated body. The thermoelectric cooling system is configured to physically contact and thermally couple the target area of the cutaneous membranes, mucous membranes, and tissue of the mucocutaneous zone to induce cryoanesthesia or analgesia. The thermoelectric cooling system includes a thermally-conductive cold tip, a thermally-conductive cooling power concentrator thermally coupled to the cold tip, at least one Peltier unit module thermally coupled to the cooling power concentrator, a heatsink thermally coupled to at least one Peltier unit module, a power source, at least one thermal sensor, and a controller operably outputting a control signal to the Peltier unit module to maintain a predetermined temperature. | 2017-10-26 |
20170304559 | Medicament Delivery Device and Cartridge - Described is a cartridge comprising a body adapted to contain a medicament, a bung slidably disposed in the body and having a distal face and a proximal face, and a light element coupled to a component of the cartridge. Further described is a medicament delivery device comprising the cartridge, a first receiver adapted to receive an optical signal from the light element and convert the optical signal into a first electrical signal, and a second receiver adapted to receive an optical signal from the light element and convert the optical signal into a second electrical signal. | 2017-10-26 |
20170304560 | Device for Detecting Moisture for an Arrangement for Monitoring an Access to a Patient - A device for detecting moisture for an arrangement for monitoring an access to a patient for a system by which, via a flexible line, a liquid is fed to a patient and/or a liquid is fed out from the patient, and in particular for monitoring the vascular access in extra-corporeal blood treatment and particularly for monitoring a central venous catheter for acute dialysis includes at least a portion which can be deformed into a sleeve and placed around the circumference of the flexible line or of a connecting system. The portion in sleeve form has fastening means for fixing it in place in the position in which it surrounds the flexible line or the connecting system. The portion in sleeve form allows the device to be fastened quickly and securely to a flexible line or a connecting system. | 2017-10-26 |
20170304561 | NEBULIZERS AND USES THEREOF - The present disclosure generally relates to the field of nebulizers for aerosol generation and methods of using same for treating diseases and disorders. | 2017-10-26 |
20170304562 | Distance Indicators for Medicinal Spray Devices - The present invention is directed to a spray applicator for spraying a tissue treatment medicant onto a tissue that has a container containing the medicant and is positioned at a proximal end of the spray applicator; a spray tip positioned at a distal end of the spray applicator; a cannula connecting the container with the spray tip; an actuatable dispensing mechanism at a proximal end of the applicator to express the medicant from the container through the cannula and through the spray tip toward the tissue; an optional pressurized gas source discharging a gas through the cannula in the vicinity of the spray tip or inside the spray tip; and a distance indicator that provides indicia of the distance between the spray tip and the tissue but does not prevent positioning the spray tip closer to the tissue than a defined distance for the distance indicator. | 2017-10-26 |
20170304563 | INHALATION DEVICE, SYSTEM AND METHOD - A device, system, and method for vaporizing substances in a pod or a cartridge, utilized for inhalation by a user. The device includes components to measure the content and dosage pods or cartridges containing substances, among other features. The device includes a graphical user interface that may be integrated with the device or implemented through a mobile device, which allows the user to transmit user data to a remote database and/or healthcare provider for personal and clinical data collection. The user data can be used for enhancing personal treatment or clinical research. | 2017-10-26 |
20170304564 | INHALABLE DRY POWDERS - The invention related to dry powders that contain a therapeutic agent. The dry powders have characteristics, e.g., they are processable and/or dense in therapeutic agent that provide advantages for formulating and delivering therapeutic agents to patients. | 2017-10-26 |
20170304565 | INHALATION DEVICE FOR USE IN AEROSOL THERAPY OF RESPIRATORY DISEASES - An inhalation device, assembly or system can include a kit and a pharmaceutical composition. The device can be adapted for administering therapeutic aerosols to pediatric patients, including neonates, infants or toddlers. The device can further include a vibrating mesh aerosol generator that can be insertable into a flow channel of the inhalation device through a lateral opening, and a valved face mask. The device can be connectable to a gas source through which a gas, such as oxygen, can be received into the flow channel at a low flow rate. | 2017-10-26 |