42nd week of 2014 patent applcation highlights part 38 |
Patent application number | Title | Published |
20140308580 | TRANSPARENT GAS BARRIER FILM, METHOD FOR PRODUCING TRANSPARENT GAS BARRIER FILM, ORGANIC EL ELEMENT, SOLAR BATTERY, AND THIN FILM BATTERY - A transparent gas barrier film that has excellent gas barrier properties and includes a transparent gas barrier layer having a very low internal stress, and a method for producing the same. The transparent gas barrier film according to the present invention includes: a resin substrate; and a transparent gas barrier layer formed over the resin substrate. The transparent gas barrier layer includes at least one kind selected from the group consisting of metals and metalloids. The transparent gas barrier layer includes a plurality of layers each having a density that changes continuously from high density to low density or from low density to high density and then cycles alternatively from low density to high density or high density to low density, respectively, once or two or more times. | 2014-10-16 |
20140308581 | Aqueous Energy Storage Devices with Organic Electrode Materials - An aqueous metal-ion battery and a method for constructing same. In one embodiment, the battery includes an aqueous electrolyte and at least one electrode comprising at least one organic electrode material. A method comprises incorporating an organic electrode material into the electrode of an aqueous metal-ion battery. The organic electrode material further comprises at least one material chosen from carbonyl compounds. | 2014-10-16 |
20140308582 | NEGATIVE ELECTRODE FOR LITHIUM ION SECONDARY BATTERIES AND METHOD FOR PRODUCING THE NEGATIVE ELECTRODE, AND LITHIUM ION SECONDARY BATTERY - Provided is a negative electrode for lithium ion secondary batteries, which can enhance the penetration of non-aqueous electrolyte, and can improve the input-output characteristics. The negative electrode includes a negative electrode core material sheet, and a negative electrode material mixture layer supported thereon. The negative electrode material mixture layer includes negative electrode active material particles, and a binder. The negative electrode material mixture layer has a plurality of pores interspersed on the surface and in the interior of the negative electrode material mixture layer. The pores have an average maximum diameter R of 45 to 125 μm. The pores have a number density of 8 to 17 pores per 1 cm | 2014-10-16 |
20140308583 | NANOCOMPOSITE ANODE MATERIALS FOR SODIUM-ION BATTERIES - The disclosure relates to an anode material for a sodium-ion battery having the general formula AO | 2014-10-16 |
20140308584 | ACTIVE MATERIAL FOR NONAQUEOUS ELECTROLYTE SECONDARY BATTERY, METHOD FOR MANUFACTURING ACTIVE MATERIAL, ELECTRODE FOR NONAQUEOUS ELECTROLYTE SECONDARY BATTERY, AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY - An active material for a nonaqueous electrolyte secondary battery contains a lithium transition metal composite oxide having an α-NaFeO | 2014-10-16 |
20140308585 | SILICON-BASED ACTIVE MATERIALS FOR LITHIUM ION BATTERIES AND SYNTHESIS WITH SOLUTION PROCESSING - Silicon based anode active materials are described for use in lithium ion batteries. The silicon based materials are generally composites of nanoscale elemental silicon with stabilizing components that can comprise, for example, silicon oxide-carbon matrix material, inert metal coatings or combinations thereof. High surface area morphology can further contribute to the material stability when cycled in a lithium based battery. In general, the material synthesis involves a significant solution based processing step that can be designed to yield desired material properties as well as providing convenient and scalable processing. | 2014-10-16 |
20140308586 | Negative Electrode for Lithium Ion Rechargeable Battery and Manufacturing Method Thereof - The present invention relates to a negative electrode for lithium ion rechargeable battery and a manufacturing method thereof. The negative electrode comprises at least one vermicular graphite and at least one pitch, wherein the vermicular graphite is fabricated by way of thermally treating an expandable graphite powder, and the pitch is adsorbed in the pores of the vermicular graphite. In the present invention, the pitch adsorbed in the vermicular graphite would be carbonized and graphitized, such that a composite graphite having multi-layer flake graphite is formed, and the composite graphite is further pulverized to a composite graphite powder. Moreover, the manufacturing method of the present invention can be used for fabricating the negative electrode for lithium ion rechargeable battery under the conditions of reducing manufacturing cost and solvent usage, so as to protect the environment from the manufacturing process pollution. | 2014-10-16 |
20140308587 | PULSED LASER CHEMICAL VAPOR DEPOSITION AND SURFACE MODIFICATION - An ultra-short pulse laser physically and/or chemically modifies a substrate surface. A laser ablation process is configured to form raised surface features on the substrate. The laser also functions as the energy source in a chemical vapor deposition (CVD) process. The laser delivers energy to the substrate with parameters such as pulse energy, size, duration, and spacing sufficient to simultaneously vaporize substrate material and cause the substrate material to react with a controlled environment that includes constituents of a desired coating composition. A battery electrode having a face with microneedle features coated with an active metal compound can be produced by the process. The active metal compound is a lithium-containing compound in a lithium-ion battery. | 2014-10-16 |
20140308588 | NEGATIVE-ELECTRODE STUFF AND NEGATIVE ELECTRODE FOR USE IN LITHIUM-ION SECONDARY BATTERY AS WELL AS LITHIUM-ION SECONDARY BATTERY - A negative-electrode stuff has negative-electrode active-material particles including: an element being capable of sorbing and desorbing lithium ions, and being capable of undergoing an alloying reaction with lithium; or/and an elementary compound being capable of undergoing an alloying reaction with lithium. The negative-electrode active-material particles includes particles whose particle diameter is 1 μm or more in an amount of 85% by volume or more of them when the entirety is taken as 100% by volume, exhibit a BET specific surface area that is 6 m | 2014-10-16 |
20140308589 | FLUID COMPRESSOR AND FUEL CELL VEHICLE - An air compressor as a fluid compressor includes: a suction port and a delivery port provided at upper and lower portions, respectively, of a pump chamber; a suction passage in communication with the inside of the pump chamber via the suction port; a delivery passage in communication with the inside of the pump chamber via the delivery port; and a driving rotor and a driven rotor provided in the pump chamber. At least a part of the suction passage is located below the suction port. | 2014-10-16 |
20140308590 | SOLID POLYMER ELECTROLYTE, METHOD OF PREPARING SOLID POLYMER ELECTROLYTE AND ELECTROCHEMICAL DEVICE - Provided is a solid electrolyte including an epitaxial thin film crystal made of an electrolyte containing at least lithium. | 2014-10-16 |
20140308591 | ALKALI METAL-OXYGEN CELL HAVING A TITANATE ANODE - An alkali metal-oxygen cell includes a negative electrode, an oxygen electrode, and a separator configured to conduct alkali metal ions. To improve the cycling stability of the negative electrode and also the cycling stability, the life, the high-current loading capability, the pulse loading capability and the safety behavior of the cell, the negative electrode includes at least one alkali metal titanate. In particular the at least one alkali metal titanate is one into or from which an alkali metal can reversibly be intercalated and deintercalated. | 2014-10-16 |
20140308592 | METHOD OF MANUFACTURING DISPERSION LIQUID FOR ELECTRODE CATALYST, DISPERSION LIQUID FOR ELECTRODE CATALYST, METHOD OF MANUFACTURING ELECTRODE CATALYST, ELECTRODE CATALYST, ELECTRODE STRUCTURE, MEMBRANE ELECTRODE ASSEMBLY, FUEL CELL AND AIR CELL - A method of manufacturing a dispersion liquid for an electrode catalyst, the method comprising a step of supporting a precious metal on the surface of a carrier by an electrodeposition process using a raw material mixed solution in which a particulate carrier is dispersed in a solvent and a compound including the precious metal element is dissolved in the solvent, wherein the carrier has oxygen reduction capability and is free of precious metal elements. | 2014-10-16 |
20140308593 | CELL SYSTEM - A cell system using air as a positive-electrode active material and a metal substance as a negative-electrode active material includes a thin film of the metal substance, a pair of reels, each end being connected to the thin film, an electrode positioned in a vicinity of a path of the thin film between each of the reels, and a molten solution that is positioned downstream of the electrode and melts the metal substance oxidized when power is generated. The metal substance may include, for example, magnesium, aluminum, zinc, lithium and iron, the electrode may include a copper electrode, and the molten solution may include a hydrochloric acid solution, a sulfuric acid solution and an acetic acid solution. The cell system includes the pair or reels to which the thin film is connected, where the pair of reels may be configured by a cartridge type. | 2014-10-16 |
20140308594 | GRADIENT POROUS ELECTRODE ARCHITECTURES FOR RECHARGEABLE METAL-AIR BATTERIES - A cathode for a metal air battery includes a cathode structure having pores. The cathode structure has a metal side and an air side. The porosity decreases from the air side to the metal side. A metal air battery and a method of making a cathode for a metal air battery are also disclosed. | 2014-10-16 |
20140308595 | Fuel Cell System - A fuel cell system includes at least one fuel cell, line elements for supplying and discharging starting materials and/or products to/from the fuel cell, and at least one condensation unit. The condensation unit is situated in at least one of the line elements and, at least in individual operating phases of the fuel cell, the condensation unit is at a lower temperature level than the areas surrounding it and the fuel cell. | 2014-10-16 |
20140308596 | METHOD AND DEVICE FOR STOPPING SOLID-OXIDE FUEL CELL SYSTEM - A SOFC system houses a reformer and a fuel cell stack in a module case. Each cell forming the fuel cell stack is made of a porous material having a composition containing at least nickel metal, includes a cell support having a gas passage through which the fuel gas from the reformer flows from an lower end to an upper end on the inside thereof, and the excessive fuel gas is combusted at the upper end of the gas passage. Here, after the power generation stops, until the temperature of the upper end of the fuel cell stack falls below the minimum oxidation temperature of the nickel metal, the supply amount of the fuel gas to the fuel cell stack is controlled in terms of a heat flow rate within a range of 0.1 to 0.5 times that during the system rated power generation. | 2014-10-16 |
20140308597 | Steam Reforming Of Methanol - The invention provides a process for producing H | 2014-10-16 |
20140308598 | FUEL CELL SYSTEMS INCLUDING SPACE-SAVING FLUID PLENUM AND RELATED METHODS - Fuel cell systems and methods having reduced volumetric requirements are described. The systems include, among other things, an enclosed region formed by the bonding of a fuel cell layer with a fluid manifold. The enclosed region transforms into a fluid plenum when, for example, a fluid exiting a manifold outlet pressurizes the enclosed region causing one or more portions of the fuel cell layer and/or the fluid manifold to deform away from each other. | 2014-10-16 |
20140308599 | GASKET DEVICE FOR A FUEL CELL STACK - Provided is a gasket device for a fuel cell stack in which gaskets of different materials are integrally molded in an anode separator (or an anode gas diffusion layer) and a cathode separator (or a cathode gas diffusion layer) to provide sealing stability at low temperatures and long-term stability at high temperatures in a fuel cell integrated with a conventional single material and evenly securing the required physical properties of the fuel cell stack gasket. | 2014-10-16 |
20140308600 | Novel Polymer Networks Based on the Benzimidazole Moiety for High Performance Polymer Electrolyte Membrane Fuel Cells - New polymeric networks bearing benzimidazole units have been prepared. These polymeric networks will combine high proton conductivity, superior mechanical properties and thermal and oxidative stability due to the existence of polar benzimidazole groups and the presence of the unique polymeric architecture. The prepared polymer networks can be used in the catalyst ink of the electrodes in high temperature PEM fuel cells. | 2014-10-16 |
20140308601 | METHOD FOR PRODUCING CERIUM-BASED COMPOSITE OXIDE, SOLID OXIDE FUEL CELL, AND FUEL CELL SYSTEM - On the other hand, the possibility of estimating the dopant ratio of a metal element to each ceria crystalline particle using integral-width or half-width obtained by XRD was considered as follows: an XRD peak is shifted depending on the dopant ratio of La to ceria; when La increases, an XRD peak is shifted to a lower angle; in XRD performed on a raw material obtained by mixing ceria crystalline particles having different dopant ratio, peaks corresponding to the respective dopant ratio exist close to each other; as a result, a peak width is widened; accordingly, the dopant ratio of a metal element to each ceria crystalline particles are supposed to vary when integral-width and half-width obtained by XRD are large. Thus, it was revealed for the first time that integral-width and half-width obtained by XRD indicate variations in dopant ratio. It should be noted that from the direct proportional relationship between the dopant ratio x and the integral-width for dopant ratio ranging from 0.35 to 0.45, integral-widths obtained by XRD are derived to be 0.10 to 0.30 for dopant ratio ranging from 0.35 to 0.45, and half-widths are derived to be 0.10 to 0.30 similarly. | 2014-10-16 |
20140308602 | COLLECTOR PLATE FOR FUEL CELLS AND METHOD FOR PRODUCING SAME - Provided are a collector plate for a fuel cell, which has low contact resistance and excellent corrosion resistance, and can be reliably used for a long period of time, while exhibiting excellent cost performance, and a method of producing the collector plate for a fuel cell. A collector plate for a fuel cell ( | 2014-10-16 |
20140308603 | TITANIUM SUBOXIDE SUPPORTS FOR CATALYST ELECTRODE OF FUEL CELL AND LOW TEMPERATURE SYNTHESIS OF TITANIUM SUBOXIDE - Titanium suboxide (Ti | 2014-10-16 |
20140308604 | PHOTO MASK AND METHOD FOR FORMING PATTERN USING THE SAME - An opening width of a main pattern is a width with which a transcription pattern is formed on a target member to be exposed by transmitted exposure light, and is a dimension of 0.8×(λ/NA)×M or less (where λ is a wavelength of the exposure light, and NA and M are a numerical aperture and a reduction ratio of a reduced projection optical system of an exposure apparatus). Each of a first auxiliary pattern adjacent to the main pattern and a second auxiliary pattern located outside the first auxiliary pattern to be adjacent thereto has a width with which a transcription pattern is not formed by the exposure light and generates diffracted light. A first distance between respective centers of the main pattern and the first auxiliary pattern is greater than a second distance between respective centers of the first auxiliary pattern and the second auxiliary pattern. | 2014-10-16 |
20140308605 | PATTERN FORMING METHOD, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, MANUFACTURING METHOD OF ELECTRONIC DEVICE, AND ELECTRONIC DEVICE - There is provided a pattern forming method comprising (i) a step of forming a film by using an actinic ray-sensitive or radiation-sensitive resin composition containing (A) a resin capable of increasing the polarity by the action of an acid to decrease the solubility for an organic solvent-containing developer, (B) a compound capable of generating an acid upon irradiation with an actinic ray or radiation, (C) a solvent, and (D) a resin substantially free from a fluorine atom and a silicon atom and different from the resin (A), (ii) a step of exposing the film, and (iii) a step of performing development by using an organic solvent-containing developer to form a negative pattern. | 2014-10-16 |
20140308606 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND GALLIUM PHTHALOCYANINE CRYSTAL - Provided is an electrophotographic photosensitive member, a process cartridge and an electrophotographic apparatus each having the electrophotographic photosensitive member that can output an image having less image defects due to a ghost phenomenon not only under a normal-temperature, normal-humidity environment but also under a low-temperature, low-humidity environment as a particularly severe condition. The electrophotographic photosensitive member includes a support and a photosensitive layer formed on the support, in which the photosensitive layer includes a gallium phthalocyanine crystal containing a specific amine compound in itself. | 2014-10-16 |
20140308607 | CHARGING MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS - The present invention relates to a charging member. The charging member comprises an electro-conductive substrate and an electro-conductive surface layer, wherein the surface layer includes a binder resin, an electro-conductive particle dispersed in the binder resin, and a resin particle that roughens the surface of the surface layer; the surface layer has a plurality of protrusions each derived from the resin particle in the surface thereof; the resin particle that forms the protrusion has a pore inside thereof; has a porosity Vt of porosity is 2.5% by volume or less as a whole; and has a region whose porosity V11 is from 5% by volume to 20% by volume, wherein the region is farthest away from the electro-conductive substrate in the resin particle, and assuming that the resin particle is a solid particle having no pores, the region corresponds to a 11% by volume-occupying region of the solid particle. | 2014-10-16 |
20140308608 | Sol-Gel Silica Additives - The present disclosure describes toner additive packages comprising two or more colloidal silicas. | 2014-10-16 |
20140308609 | POSITIVELY CHARGEABLE TONER FOR NONMAGNETIC MONO-COMPONENT DEVELOPMENT SYSTEM - The invention addresses the problem of providing a positively chargeable toner for nonmagnetic mono-component development systems, which is free from image density reduction, back ground and toner scattering inside the machine that are caused by insufficient electrification and which has excellent toner starvation on black page, without impairing the durability. In the positively chargeable toner for nonmagnetic mono-component development system, which at least comprises a binder resin, a colorant and a charge control agent, a styrene-acrylic resin is used as the binder resin, and the toner comprises: polytetrafluoroethylene fine particles; and inorganic fine particles that have been surface-treated with an amino group-containing treating agent. | 2014-10-16 |
20140308610 | TONER AND METHOD FOR MANUFACTURING TONER PARTICLES - The present invention provides a toner that contains an azo pigment well-dispersed in a binder resin and has a satisfactory color tone. | 2014-10-16 |
20140308611 | TONER - It is an object of the present invention to provide a toner capable of being fixed at low energy and forming an image with high resistance to external forces, such as rubbing and scratching. | 2014-10-16 |
20140308612 | METHOD AND SYSTEM FOR MAGNETIC ACTUATED MIXING TO PREPARE LATEX EMULSION - A method and system for magnetic actuated mixing which use magnetic particles and magnetic field to facilitate the mixing for preparing latex emulsion. In embodiments, a suitable process includes dissolving a resin in an organic solvent, optionally adding a surfactant, adding a neutralization agent and water, adding magnetic particles, and subjecting the mixture to a magnetic actuated mixing to form a latex emulsion. In embodiments, the latex emulsion thus produced may be utilized to form a toner. | 2014-10-16 |
20140308613 | CARBOXYL-CONTAINING RESIN, RESIN COMPOSITION FOR SOLDER MASK, AND METHOD OF PREPARING CARBOXYL-CONTAINING RESIN - The carboxyl-containing resin in accordance with the present invention has a structure resulting from addition of a carboxylic acid to at least one of epoxy groups of a biphenyl novolac epoxy resin. The carboxylic acid includes at least a polybasic acid. | 2014-10-16 |
20140308614 | PATTERNING PROCESS, RESIST COMPOSITION, POLYMER, AND MONOMER - A negative pattern is formed by applying a resist composition onto a substrate, prebaking, exposing to high-energy radiation, PEB, and developing the exposed resist film in an organic solvent developer to dissolve the unexposed region of resist film. The resist composition is based on a polymer comprising recurring units (a1) of formula (1) wherein R | 2014-10-16 |
20140308615 | CYCLIC COMPOUND, METHOD FOR PRODUCING SAME, COMPOSITION, AND METHOD FOR FORMING RESIST PATTERN - A cyclic compound having a molecular weight of 500 to 5000 is represented by the following formula (1), | 2014-10-16 |
20140308616 | COMPOSITION OF AN AQUEOUS ETCHANT CONTAINING A PRECURSOR OF OXIDANT AND PATTERNING METHOD FOR CONDUCTIVE CIRCUIT - The present invention is primarily related to the composition of an aqueous etchant containing a precursor of oxidant and patterning methods for conductive circuits, in which the chemical structure of the precursor contains chlorine and can produce oxidants through various reactions. And, the patterned conductive circuits can be used for electronic devices, including printed electronics, sensors, displays, organic light emitting diodes (OLED), touch panels, electronic circuit boards, electrodes, electroluminescent (EL) films, antennas, and solar cells. | 2014-10-16 |
20140308617 | Method for Improving Print Performance in Flexographic Printing Plates - A method of making a relief image printing element from a photosensitive printing blank is provided. The method comprising the steps of: | 2014-10-16 |
20140308618 | Organic Solution for Surface Treatment of Induim Zinc Oxide Substrate and Method of Preparing Display Substrate Using the Same - Disclosed are an organic solution for surface-treating an indium zinc oxide (IZO) substrate that is used for surface treatment of an indium zinc oxide (IZO) substrate, and includes an organic material, and a method of preparing a display substrate using the same. | 2014-10-16 |
20140308619 | LEAN PREMIX BURNER HAVING CENTER GAS NOZZLE - A lean premix burner has a center fire nozzle, which includes radial gas outlets and a ring of outlets. The gas outlets from the center fire nozzle are fed from a manifold. The center fire gas is controlled separately from the main gas supply, which has several advantages, including enhanced turn down capability. | 2014-10-16 |
20140308620 | PULVERIZED COAL FIRED BOILER WITH WALL-ATTACHMENT SECONDARY AIR AND GRID OVERFIRE AIR - The present invention relates to a pulverized coal fired boiler with wall-attachment secondary air and grid overfire air. Primary burners including primary air spouts, secondary air spouts and close coupled overfire air spouts arranged at intervals along the height direction of a hearth are arranged on four corners of the hearth. Two-way wall-attachment secondary air spouts and one-way wall-attachment secondary air spouts are arranged from bottom to top in a primary combustion zone where the primary burners are located. One-way wall-attachment secondary air spouts are arranged in a reduction zone between the primary burners and the top overfire air spouts, and grid overfire air spouts are arranged in a burnout zone where the overfire air is supplied. By adopting the pulverized coal fired boiler with wall-attachment secondary air and grid overfire air according to the present invention, the NO amount generated in the hearth is reduced, the NO reduction rate along a flame is improved, the coke burnout rate is improved, less coke which is not burnt out enters into the burnout zone, slagging on the water-cooled wall is reduced, and ultralow emission of NOx may be realized on the premise that the combustion efficiency is not reduced, slag is not agglomerated in the hearth and the flue gas temperature deviation is small. | 2014-10-16 |
20140308621 | SINTERING APPARATUS - A sintering apparatus comprising a furnace core tube having an opening in a top end through which the soot deposition body is inserted, and having atmospheric gas introduced therein from below and expelled upward; a shaft from which the soot deposition body hangs; a lid that has the shaft inserted therethrough and can cover the opening; a heating furnace that heats the soot deposition body; an internal lid in a top portion of the furnace core tube that divides the top portion of the furnace core tube into an upper region and a lower region; and a gas flow path that connects the two regions to each other and has the atmospheric gas flow therethrough. Total cross-sectional area, relative to movement direction of the atmospheric gas, of the gas flow path is less than cross-sectional area, relative to movement direction of the atmospheric gas, of the furnace core tube. | 2014-10-16 |
20140308622 | SELF-LIGATING ORTHODONTIC BRACKET - A self-ligating orthodontic bracket comprising a body and a locking shutter. A mesio-gingival reference plane is defined tangent to a lingual-most point of the archwire slot. The body further includes an occlusal-gingival opening that intersects the reference plane. The locking shutter includes a lingual end located in the opening at a closed lingual location when the locking shutter is in a closed position, and at an open lingual location when the locking shutter is in an open position. The locking shutter further includes a labial end located at a closed labial location when the locking shutter is in the closed position and at an open labial location when the locking shutter is in the open position. A first occlusal-gingival distance from the closed lingual location to the open lingual location is at least about 70% of a second occlusal-gingival distance from the closed labial location to the side surface. In addition, the first occlusal-gingival distance is at least about 60% of a third occlusal-gingival distance from the closed lingual location to an end of a tie wing. | 2014-10-16 |
20140308623 | COMPUTER FABRICATION OF DENTAL PROSTHETICS - A method is disclosed to fabricate a dental prosthesis by obtaining an image of the patient's dentition and generating a three-dimensional model of the dentition; positioning a portion of the dentition into a computer model of a mill blank; defining a margin region surrounding a dental object; defining an abutment ditch outside of said margin; generating a milling model having two virtual portions including the margin region and the abutment ditch region; and milling the dental prosthesis with a differential speed, wherein the milling of the abutment ditch portion is done at a higher speed than the milling of the prosthesis portion. | 2014-10-16 |
20140308624 | METHOD AND APPARATUS FOR PREPARING REMOVABLE DENTAL PROSTHESIS - A method for manufacturing a removable dental prosthesis using a three-dimensional (3D) printer includes receiving dental impressions of a patient obtained using a dental impression tray assembly, the dental impressions including a bite registration and at least a mandibular impression or a maxillary impression; receiving information related to the patient's jaw relations obtained using the dental impression tray assembly, the jaw relations including a vertical dimension and a centric relation obtained during the patient's single visit to a dentist; scanning the received dental impressions with a 3D scanner to provide data representative of an edentulous shape of the patient; generating a 3D model of the dental prosthesis based on the data and the received information related to the patient's jaw relations using 3D design software; displaying the generated 3D model on a display, allowing customization of the 3D model; and 3D printing the dental prosthesis according to the 3D model. | 2014-10-16 |
20140308625 | DEVICE FOR DELIVERY OF A TOOTH WHITENING AGENT - A delivery device ( | 2014-10-16 |
20140308626 | DENTAL ASPIRATION DEVICE AND METHOD OF USE - A dental aspiration device comprising an inside housing having a proximal portion and a distal portion with an interior surface; an outside housing having a proximal portion and a distal portion with an interior surface; at least one of the interior surfaces of the inside housing and the outside housing including vacuum channels; a hinge connection mechanism hingeably connecting the proximal portions of the inside housing and the outside housing; and a locking mechanism for removably attaching the distal portions of the inside housing and the outside housing to each other. | 2014-10-16 |
20140308627 | PROXIMAL TOOTH SEPARATOR - The present disclosure is directed to a proximal tooth separator. One embodiment comprises a handle and at least one separator connected to an end. The at least one separator comprising rigid metals, steel, titanium, or other materials suitable for separating teeth, and being sized so as to appropriately separate the teeth as known to those of skill in the art. | 2014-10-16 |
20140308628 | METAL MATERIALS HAVING A SURFACE LAYER OF CALCIUM PHOSPHATE, AND METHODS FOR PREPARING SAME - The present invention relates to a multi-layer material comprising a metal or metal alloy substrate, the metal or alloy substrate being coated with an intermediate layer comprising at least one ceramic or crystalline, or partially crystalline, structure, including a metal or a metal alloy, said intermediate layer being coated with a layer of calcium phosphate having a cellular nanometric structure, and uses thereof. | 2014-10-16 |
20140308629 | METHODS AND APPARATUS FOR MONITORING AND ENCOURAGING HEALTH AND FITNESS - Methods and apparatus are provided for monitoring and encouraging health and fitness. In accordance with a first aspect, an apparatus is provided that is adapted to assist in weight loss and exercise. The apparatus comprises a personal digital assistant (PDA) having computer program code adapted to assist in at least one of calorie counting, meal selection, meal suggestion, weight monitoring, weight loss or gain monitoring, fat consumption monitoring, sugar consumption monitoring and salt consumption monitoring. The PDA also includes computer program code adapted to display historical data regarding at least one of calorie counting, meal selection, meal suggestion, weight monitoring, weight loss or gain monitoring, fat consumption monitoring, sugar consumption monitoring and salt consumption monitoring. Numerous other embodiments are provided, as are methods, systems and computer program products. | 2014-10-16 |
20140308630 | MULTILINGUAL TRANSLATION DEVICE DESIGNED FOR CHILDHOOD EDUCATION - Portable, real time voice translation systems, and associated methods of use, are provided. The systems include a translation system for use on a single unit, portable computing device and operable for accessing a multilanguage database, selecting a source language from a plurality of source languages and a destination language from a plurality of destination languages, inputting a source phrase, transmitting the source phrase to a speech recognition module, a translation engine, and a template look-up engine for finding the phrase template associated with the destination phrase from among the multiple languages. The spoken translation is then output in the selected destination language. The translation system has a total time between the input of the source phrase and output of the destination phrase that is no slower than 0.010 seconds, and a communications interface operable for communicating with a second computer system. | 2014-10-16 |
20140308631 | SYSTEMS AND METHODS FOR COMPUTERIZED INTERACTIVE SKILL TRAINING - The present invention is directed to interactive training, and in particular, to methods and systems for computerized interactive skill training. An example embodiment provides a method and system for providing skill training using a computerized system. The computerized system receives a selection of a first training subject. Several related training components can be invoked, such as reading, watching, performing, and/or reviewing components. In addition, a scored challenge session is provided, wherein a training challenge is provided to a user via a terminal, optionally in video form. | 2014-10-16 |
20140308632 | HAZARD-ZONE INCIDENT COMMAND TRAINING AND CERTIFICATION SYSTEMS - Systems designed to train and certify persons to act as at least one responsible person(s) for decision making and management operations as part of an emergency response at incidents that contain at least one hazard zone; such hazard zone defined as any work area which contains a hazard that can injure or kill, for example, burning structures, hazardous material incidents, roadways with active traffic, natural disaster sites, and/or other emergency response scenes. | 2014-10-16 |
20140308633 | Fire Safety Simulator - The system has in one embodiment a representative structure having a predefined area having a plurality of changeable targets, each of the changeable targets having at least first and second positions. At least one aiming device has an activator for effecting a change of a selected changeable target between the first and second positions thereof when the activator is triggered while the aiming device is aimed at the selected changeable target. At least one signal device is activated by changes from respective first positions to respective second positions of at least some of the changeable targets. | 2014-10-16 |
20140308634 | METHOD AND SYSTEM FOR ACTUALIZING PROGRESSIVE LEARNING - Disclosed herein is a web-based learning apparatus and a method for progressive learning. The apparatus and a method enables identifying a learning flow pattern of the user for a particular topic by mapping the synchronicity of events with interest graphs in similarity sets. Further, the shift in user learning pattern and interest graph is recorded to enable the system derive an updated learning matrix of the user that is capable of presenting and recommending to the user of new expanded matrix comprising topics of his evolving interest. | 2014-10-16 |
20140308635 | SYSTEM AND METHOD FOR GENERATING A TRAVEL STRESS INDEX - A method for calculating a traveler stress index may include retrieving a dataset including transaction data on a plurality of trips from a storage device; calculating, using at least one processor, a maximum possible lost time value for each respective trip in at least a first subset of the plurality of trips; calculating, using the at least one processor, an actual lost time value for each respective trip in the first subset; summing the calculated maximum possible lost time values and actual lost time values to determine a total MPLT value for the first subset and a total ALT value for the first subset, respectively; and generating a stress index for the first subset by dividing the ALT value by the MPLT value. | 2014-10-16 |
20140308636 | PROVIDING RECOMMENDATIONS BASED ON DETECTED STRESS AND A PREDICTED TYPE FOR AN INDIVIDUAL - The methods and systems described herein may involve determining at least one lifeotype of at least one individual, analyzing the at least one lifeotype, and delivering content to at least one individual based on the analysis. The methods and systems described herein may involve providing a game, determining at least one lifeotype of at least one player of the game, analyzing the at least one lifeotype, and affecting the game play based on the analysis. The methods and systems described herein may involve providing an interactive space, determining at least one lifeotype of at least one individual in the space, analyzing the at least one lifeotype, and modifying at least one attribute of the space based on the analysis. | 2014-10-16 |
20140308637 | METHODS AND APPARATUSES FOR FACILITATING A CHANGE FOR AN INDIVIDUAL - Methods and apparatus for facilitating a change for an individual. The methods and apparatus may include determining a current stage of change for an individual based upon information received about making a change. The methods and apparatus may also include setting up a sounding board to communicate with a select number of individuals to receive feedback and/or advice for facilitating a change. | 2014-10-16 |
20140308638 | USING AN EARNED POINTS SYSTEM TO PROVIDE INTERNET ACCESS - Systems and methods to restrict or meter internet access and usage using virtual currency based on chores, behaviors, and activities. The systems and methods allow controlled internet access using positive rewards, negative rewards, positive punishment, and negative punishment. Described herein is a system and method to create chores, behaviors, and activities that either grant or remove access or allow the earning of points with the conversion of the points into recreational internet access time, money, merchandise, or other reward. | 2014-10-16 |
20140308639 | DATA FROM WEARABLE SENSOR DEVICES TO MANAGE EDUCATIONAL CONTENT - The methods and systems described herein may involve determining at least one lifeotype of at least one individual, analyzing the at least one lifeotype, and delivering content to at least one individual based on the analysis. The methods and systems described herein may involve providing a game, determining at least one lifeotype of at least one player of the game, analyzing the at least one lifeotype, and affecting the game play based on the analysis. The methods and systems described herein may involve providing an interactive space, determining at least one lifeotype of at least one individual in the space, analyzing the at least one lifeotype, and modifying at least one attribute of the space based on the analysis. | 2014-10-16 |
20140308640 | Method to Improve Skilled Motion Using Concurrent Video of Master and Student Performance - A method to improve a skilled motion through holistic viewing, in-place and/or across a horizontal plane, involving a video camera, computer, and monitor system that displays a prerecorded video clip of a master's performance selected from a library of video clips recorded in a plurality of perspectives and also displays a live video feed of the student performing the master's motion in the same perspective, controlled by placement of the video camera relative to the student. Slight variations of the master's skilled motion loop repeatedly and contain blacked-out segments such that the student dynamically performs the selected motion both with and without the visual guidance of the master's performance. The video library includes invention-specific tutorials on why to use specific digital video playback controls known to the art such as horizontal orientation, freeze frame, slow motion, as well as recording the live video to disk. | 2014-10-16 |
20140308641 | SHOELACE TYING AIDE FOR DEVELOPMENT AND LEARNING OF THE SHOELACE TYING PROCESS - A shoelace tying device which acts as a learning aide and assistant for individuals who may lack the capacity either mentally and/or physically to fully grasp and complete all of the steps required to tie one's shoe laces. The device consists of a solid thin piece of material which fastens to a shoe's shoelace with a clip on its backside. The device also consists of four holes on the top which pass from front to back and two hooks on the bottom end of the device. The two inner holes are used to cinch the starting knot of a double bow knot tight and hold it in place. The two outer holes and hooks are used to assist in forming and holding the loops in place while the user forms the knot using their method of choice. In addition, the front contains an image which is intended to excite and inspire the user to learn one or more of the many loop type methods used to tie one's shoelaces. | 2014-10-16 |
20140308642 | Simulated Medical Device - A simulated medical device may include a visual display, a processor, a memory, a switch connected to a power supply, a body housing the visual display, the processor, the memory, and the switch, and a simulated probe coupled to the body. The body is configured to receive internally at least a portion of the simulated probe. The switch is configured to provide a supply of power to the processor when the at least a portion of the simulated probe is external to the body and to disconnect the supply of power to the processor if the at least a portion of the simulated probe is inserted in the body. The processor is configured to cause the visual display to display at least a first simulated medical value in response to receiving the supply of power at the processor and after a time duration indicated by a simulated acquisition time. | 2014-10-16 |
20140308643 | Ultrasound Phantom Models, Materials, and Methods - Devices, systems, and methods appropriate for use in medical training that include materials that better mimic natural human tissue are disclosed. In one aspect a polysiloxane mixture for simulating human biological tissue, especially human breast tissue, is disclosed. In another aspect, a method of manufacturing a biological tissue ultrasound phantom is disclosed. In another aspect, a human breast tissue models are disclosed. In some instances, the human breast tissue model includes at least one simulated pathological structure that simulates such pathologies as a cyst, a medullary carcinoma, a ductal carcinoma, an infiltrating scirrhus carcinoma, a lobular carcinoma, and a fibroadenoma. | 2014-10-16 |
20140308644 | Foreign Body Removal System - A system and method for the practice of removing foreign objects from a human eye. The system can be mounted onto a biomicroscope such that a trainee can utilize the device to practice careful removal of foreign objects on or embedded in an artificial eyeball. | 2014-10-16 |
20140308645 | CUSTOMIZED TESTS THAT ALLOW A TEACHER TO CHOOSE A LEVEL OFDIFFICULTY - An educational electronic book (e-Book) facility that may be suitable for use in public school classrooms and many other environments may be based on an encapsulated HTML technology to facilitate complete interactive operation without use or risks associated with an external network connection, such as the Internet. | 2014-10-16 |
20140308646 | Method and System for Creating Interactive Training and Reinforcement Programs - Methods and system for creating an interactive training and reinforcement programs. Training program content is delivered to training participants in accordance with a data structure representing a timeline or schedule. A graphical representation of the timeline is presented to a trainer/user to construct a training program. Training program content comprises scheduled messages in the form of emails, videos, photos, pdf files, links to databases, text messages, questions, and surveys. The content including answers to questions is weighted. The timeline is modified in accordance with weighted scoring of the content delivered and responses by participants. A network-accessible computer system ( | 2014-10-16 |
20140308647 | COMPUTER-BASED VIRTUAL TRAINER - Embodiments of a system and method for generating a computer-based virtual training application are generally described herein. One embodiment for the method comprises generating input data, converting the input data to a predefined format for use by a virtual trainer framework, and generating the virtual training application comprising interactive displays, configured for use on a computer, in response to the virtual trainer framework rendering the input data in the predefined format. | 2014-10-16 |
20140308648 | SYSTEM FOR QUESTION ANSWERING - A system includes: a controller; a memory coupled to the controller, wherein the memory is configured to store program instructions executable by the controller; wherein in response to executing the program instructions, the controller is configured to: in response to receiving a request to generate an advisor list, wherein the request includes a topic area value, access a database including a plurality of advisor records, wherein each advisor record includes at least one topic area value, an advisor merit score value, and a recency of registration value; selecting advisor records for use in the advisor list, wherein the selected advisor records include at least three of the advisor records, including a first record selected based on advisor merit score values and a second record based on recency of registration values; and generate the advisor list using the selected advisor records. | 2014-10-16 |
20140308649 | CUMULATIVE TESTS IN EDUCATIONAL ASSESSMENT - New methods and systems are disclosed for improved assessments of student progress in education. Using a new concept called a cumulative test, examinee ability may be measured by combining discrete measures into one test representing ability measured over an extended period of time. (FIG. | 2014-10-16 |
20140308650 | EVALUATION CONTROL - Systems and methods for evaluation control are disclosed herein. An evaluation control system can be used in evaluating one or several artifacts. The evaluation control system can be used to verify an evaluation and/or to provide evaluation training. The evaluation system can include a processor and a user device. The evaluation system can provide one or several artifacts and evaluation criteria to an evaluator. The evaluation system can receive one or several tags associated with the one or several artifacts and/or the evaluation criteria. The one or several tags can include information that, in connection with the evaluation criteria, support an evaluation and/or score for the one or several artifacts. | 2014-10-16 |
20140308651 | 3-D Interactive Tattoo Practice Skin - A tattoo-able practice prosthetic device may be worn to protect the wearer of a permanent mark, while allowing tattoo student to begin to understand the art of tattooing, by leaving that permanent mark on a non-permanent device. | 2014-10-16 |
20140308652 | SOLUTION UTILIZING NITROGEN CONTAINED WATER FOR PRESERVING OR FLUSHING ORGANS FOR TRANSPLANTATION, METHOD FOR PREPARING THE SOLUTION AND METHOD FOR PRESERVING OR FLUSHING ORGANS FOR TRANSPLANTATION UTILIZING THE SOLUTION - A solution utilizing nitrogen contained water for preserving or flushing organs for transplantation, wherein a solvent of the solution is the nitrogen contained water which was prepared by adding nitrogen gas to water and reducing dissolved oxygen. A method for preparing a solution for preserving or flushing organs for transplantation, comprising a step of dissolving a composition comprising a plurality of component materials which are intended to be solutes of the solution in liquid which is intended to be a solvent of the solution. The liquid which is intended to be the solvent of the solution is the nitrogen contained water which was prepared by adding nitrogen gas to water and reducing dissolved oxygen. | 2014-10-16 |
20140308653 | METHODS AND SYSTEMS FOR ASSESSING EX-VIVO ORGAN HEALTH - Methods of determining the health of an organ, such as a transplant organ, by measuring the ex-situ oxygen consumption rate of the organ. Systems for preserving and transporting organs while monitoring viability by measuring oxygen consumption rates. | 2014-10-16 |
20140308654 | ORGAN PERFUSION SYSTEMS - An organ perfusion system comprises: a perfusion fluid circuit ( | 2014-10-16 |
20140308655 | Device for Manipulating Biological Materials in a Process of Cryopreservation and a Use of Such a Device - The device comprises a loading portion ( | 2014-10-16 |
20140308656 | METHODS FOR PRODUCTION AND USE OF SUBSTANCE-LOADED ERYTHROCYTES (S-IEs) FOR OBSERVATION AND TREATMENT OF MICROVASCULAR HEMODYNAMICS - Disclosed herein are methods, kits, and compositions for medical imaging relating to fluorescent dyes entrapped in erythrocytes. Also disclosed therein are methods, and compositions further comprising erythrocytes entrapping at least one therapeutically active agent, as well as methods for releasing the entrapped therapeutically active agent(s). Disclosed herein also are methods for preparation of the cells entrapping dye and therapeutically active agent(s) in a freeze-dried form that makes them readily available and easy to use in a clinical environment. | 2014-10-16 |
20140308657 | SERINE PROTEASE INHIBITOR KAZAL ANTIBODIES - This invention describes a relevant etiology of cancer and a novel anti-cancer therapeutic strategy, based on the discovery that a protein named serine protease inhibitor (SPIK/SPINK/PSTI) was up-regulated by hepatitis B and C virus infections consequently suppressing the cell apoptosis. Accordingly, this invention provides an inhibitor of SPIK and/or a technology of suppression of over-expression of SPIK in cells. The inhibitors include: 1) chemical compounds, which can inhibit SPIK transcripts, protein activity, and gene expression, 2) SPIK siRNA (RNAi gene silence or dsRNA of SPIK, 3) DNA anti-sense and anti-SPIK antibody. Further, this invention provides a method of using the inhibitor as an anti-cancer agent to re-instate cancer cell apoptosis (e.g., serine protease dependent cell apoptosis). Also provided is an anti-SPIK antibody specific for an epitope comprising the first nine amino acids of intact SPIK. Further, a diagnostic kit is provided comprising at least one antibody specific for an epitope comprising the first nine amino acids of intact SPIK to diagnose patients exhibiting disease symptoms or at risk for developing a disease, wherein the disease is HBV infection, HCV infection, hepatitis, cancer or hepatic cancer. | 2014-10-16 |
20140308658 | UTILITIES OF STIMULATED WHOLE BLOOD CULTURE SYSTEMS - The invention describes a method for determining how to stimulate, monitor and/or inhibit virus production in whole blood culture. The invention relates to a test kit for performing the method and to the use of a suitable blood sampling system. The system can be used to determine how to activate or target latently HIV-infected cells, for clinical management of HIV treatments and for personalized therapeutic strategies. | 2014-10-16 |
20140308659 | Liquid to Liquid Biological Particle Concentrator - A rapid one-pass liquid filtration system efficiently concentrates biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. Additional concentration stages may be added in “cascade” fashion, in order to concentrate particles below the size cut of each preceding stage remaining in the separated fluid in a concentrated sample suspension. This process can also be used to create a “band-pass” concentration for concentration of a particular target size particle within a narrow range. | 2014-10-16 |
20140308660 | METHOD FOR DISCRIMINATION OF METAPLASIAS FROM NEOPLASTIC OR PRENEOPLASTIC LESIONS - The present invention relates to a method for discrimination of p16.sup.INK4a overexpressing metaplasias from neoplastic or preneoplastic p16.sup.INK4a overexpressing lesions by determination of the level of high risk HPV encoded gene-products such as e.g. HPV E2 and/or HPV E7 molecules in biological samples in the course of cytological testing procedures. The method thus enables for reduction of false positive results in the p16.sup.INK4a based detection of anogenital lesions in cytological testing procedures. | 2014-10-16 |
20140308661 | SYSTEMS AND METHODS FOR MULTI-ANALYSIS - Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample. | 2014-10-16 |
20140308662 | MSP NANOPORES AND RELATED METHODS - Provided herein are | 2014-10-16 |
20140308663 | METHOD OF NUCLEIC ACID AMPLIFICATION AND MEASURING REAGENT AND REAGENT KIT THEREFOR - The object of the present invention is to provide a method that allows stable amplification of an internal standard material while maintaining an accurate assay value for a target nucleic acid in a nucleic acid detection system involving the use of an internal standard material and a reagent kit used therefor. The present invention relates to a method for nucleic acid amplification comprising preventing an internal standard amplification product from affecting amplification reaction of a target nucleic acid by performing amplification of an internal standard material prior to amplification of the target nucleic acid in the method for amplifying a target nucleic acid in a sample using an internal standard material and a reagent and reagent kit used therefor. | 2014-10-16 |
20140308664 | Compounds and Methods for the Enrichment of Mutated Nucleic Acid from a Mixture - The detection of the presence of rare somatic mutations from a biological sample is often challenging due to the simultaneous presence of a vast excess of wild-type DNA. The present invention describes novel compounds and methods that would allow the enrichment of mutant DNA by depleting amplifiable wild-type DNA. | 2014-10-16 |
20140308665 | DIAGNOSIS OF HEREDITARY SPASTIC PARAPLEGIAS (HSP) BY DETECTION OF A MUTATION IN THE KIAA1840 GENE OR PROTEIN - An ex vivo method of diagnosing or predicting an hereditary spastic paraplegias (HSP) in a subject is provided which comprises detecting a mutation in the KIAA1840 gene or protein (spatacsin), wherein that mutation is indicative of an hereditary spastic paraplegias (HSP). | 2014-10-16 |
20140308666 | DEVELOPMENT OF NOVEL DETERGENTS FOR USE IN PCR SYSTEMS - This disclosure relates to novel detergents for use in various procedures including, for example, nucleic acid amplification reactions such as polymerase chain reaction (PCR). Methods for preparing the modified detergents are also described. | 2014-10-16 |
20140308667 | METHODS FOR ANALYZING NUCLEIC ACIDS - The invention generally relates to methods for analyzing nucleic acids. In certain aspects, methods of the invention involve obtaining a sample including a nucleic acid template. A plurality of molecular inversion probes are tiled across a portion of the template. The probes are designed such that immediately adjacent probes hybridize to opposite strands of the nucleic acid template and probes on the same strand hybridize to the template in an overlapping manner. A region between targeting arms of a plurality of the molecular inversion probes is filled-in with nucleotides, and the filled-in region of a plurality of the probes is analyzed to obtain sequence information about the nucleic acid template. | 2014-10-16 |
20140308668 | Method of Determining Susceptibility of a Tumor Cell to a Chemotherapeutic Agent: Novel Use of Herpes SImplex Virus - The present invention provides a method of determining if a tumor cell is susceptible to killing by a chemotherapeutic agent, comprising: (a) providing a tumor cell; (b) infecting said tumor cell with a herpes simplex virus or a herpes simplex virus defective in an immediate early gene selected from the group consisting of ICP27, ICP4, and ICP22; and (c) determining the presence of apoptotic killing of said tumor cell, wherein the presence of apoptotic killing is indicative of susceptibility to said chemotherapeutic agent. Chemotherapeutic agent may include doxorubicin, etoposide, paclitaxel, cisplatin, or 5-fluororuacil. The present invention also provides a herpes simplex virus promoter construct having a lacZ gene to assess tumor resistance to chemotherapeutic agents. | 2014-10-16 |
20140308669 | METHODS FOR OBTAINING SINGLE CELLS AND APPLICATIONS OF SINGLE CELL OMICS - The present application provides methods for obtaining single cells from a sample. Methods for isolating and analyzing molecular features obtained from a single cell are also disclosed herein. For example, individual circulating tumor cells (CTCs) from a sample such as a patient's blood sample can be identified and obtained using methods disclosed herein, and picked for further analysis. | 2014-10-16 |
20140308670 | SIMULTANEOUS EXTRACTION OF DNA AND RNA FROM FFPE TISSUES - The present provides methods and kits for extracting DNA and RNA from FFPE tissues and samples. | 2014-10-16 |
20140308671 | Sampling Device - The present invention generally relates to devices, systems, and methods for acquiring and/or dispensing a sample without introducing a gas into a microfluidic system, such as a liquid bridge system. An exemplary embodiment provides a sampling device including: a sampling member for acquiring or dispensing a sample; and a supply of a fluid that is immiscible with the sample; in which the device is configured to provide a continuous flow of immiscible fluid enveloping the sampling member. | 2014-10-16 |
20140308672 | DNA POLYMERASES WITH INCREASED 3'-MISMATCH DISCRIMINATION - Disclosed are mutant DNA polymerases having increased 3′-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases. | 2014-10-16 |
20140308673 | METHODS FOR NUCLEIC ACID MANIPULATION - A method for replicating and amplifying a target nucleic acid sequence is described. A method of the invention involves the formation of a recombination intermediate without the prior denaturing of a nucleic acid duplex through the use of a recombination factor. The recombination intermediate is treated with a high fidelity polymerase to permit the replication and amplification of the target nucleic acid sequence. In preferred embodiments, the polymerase comprises a polymerase holoenzyme. In further preferred embodiments, the recombination factor is bacteriophage T4 UvsX protein or homologs from other species, and the polymerase holoenzyme comprises a polymerase enzyme, a clamp protein and a clamp loader protein, derived from viral, bacteriophage, prokaryotic, archaebacterial, or eukaryotic systems. | 2014-10-16 |
20140308674 | Characterizing Melanoma - The presently disclosed subject matter provides methods of characterizing a melanoma in a subject by measuring amounts of one or more RNAs, miRNAs, and/or polypeptides present in cancer-derived microvesicles isolated from a biological sample from the subject. | 2014-10-16 |
20140308675 | MUTAGENICITY TEST METHOD USING MAMMALIAN CELLS - Provided is a test method that allows mutagenicity on a mammal including a human to be confirmed accurately and simply in a short time. Specifically, provided is a mutagenicity test method, including the steps of: (1) culturing a transformant of a mammalian cell harboring a recombinant vector including a p53 binding sequence, a minimal promoter that can function in the mammalian cell, and a reporter gene linked so that the gene can be expressed by the minimal promoter, in the presence of a test substance for a predetermined time; and (2) assessing whether or not the test substance affects an expression amount of the reporter gene in the transformant by comparing an expression amount of the reporter gene in the transformant cultured in the step (1) to an expression amount of the reporter gene in the transformant free of contact with the test substance. | 2014-10-16 |
20140308676 | CITRULLINATED PROTEINS: A POST-TRANSLATED MODIFICATION OF MYOCARDIAL PROTEINS AS MARKER OF PHYSIOLOGICAL AND PATHOLOGICAL DISEASE - Disclosed herein are methods for diagnosing cardiovascular disease. The methods comprise detection of citrullinated proteins. | 2014-10-16 |
20140308677 | PROTEINS AND METHOD FOR DETECTION OF LYME DISEASE - Recombinant | 2014-10-16 |
20140308678 | SMYD2 AS A TARGET GENE FOR CANCER THERAPY AND DIAGNOSIS - The present invention arises from the discovery that the SMYD2 gene is both specifically over-expressed in cancer and involved in cancer cell survival. The present invention features methods for detecting or diagnosing the presence of or predisposition for developing cancer, using the SMYD2 gene as a diagnostic marker. The present invention further provides methods of screening for therapeutic substances useful in either or both of the treatment and prevention of cancer. | 2014-10-16 |
20140308679 | Fluorometry - The invention relates to fluorometry, and in particular to methods and apparatus for time-delayed detection of fluorescence in a sample, for example for use in a clinical setting. Exemplary embodiments disclosed relate to a fluorometer ( | 2014-10-16 |