41st week of 2011 patent applcation highlights part 42 |
Patent application number | Title | Published |
20110251227 | ANALGESIC AGENTS - The invention provides a compound of formula (I) or a salt thereof, as well as compositions comprising such compounds. The compounds and compositions are useful as analgesics. | 2011-10-13 |
20110251228 | NALMEFENE HYDROCHLORIDE DIHYDRATE - The present invention relates to the Nalmefene hydrochloride dihydrate, methods of manufacturing Nalmefene hydrochloride dihydrate, a pharmaceutical composition comprising Nalmefene hydrochloride dihydrate and a method of treatment comprising administering Nalmefene hydrochloride dehydrate. | 2011-10-13 |
20110251230 | THERAPEUTICS FOR NEUROLOGICAL DISORDERS - The present invention relates to therapeutic compounds that are Nrf2-ARE pathway activators suitable for the treatment of diseases known to be mediated by oxidative stress such as motor neurone disease. The invention also includes compounds identified by methods of the invention for treatment of neurogenerative diseases. | 2011-10-13 |
20110251231 | Modified release compositions comprising tacrolimus - A modified release composition comprising tacrolimus releases less than 20% w/w of the active ingredient within 0.5 hours when subjected to an in vitro dissolution test using USP Paddle method and using 0.1 N HCl as dissolution medium and has increased bioavailability by effectively reducing or even avoiding the effects of CYP3A4 metabolism. The modified composition may be coated with an enteric coating; and/or may comprise a solid dispersion or a solid solution of tacrolimus in a hydrophilic or water-miscible vehicle and one or more modifying release agents; and/or may comprise a solid dispersion or a solid solution of tacrolimus in an amphiphilic or hydrophobic vehicle and optionally one or more modifying release agents. | 2011-10-13 |
20110251232 | Modified release compositions comprising tacrolimus - A modified release composition comprising tacrolimus releases less than 20% w/w of the active ingredient within 0.5 hours when subjected to an in vitro dissolution test using USP Paddle method and using 0.1 N HCl as dissolution medium and has increased bioavailability by effectively reducing or even avoiding the effects of CYP3A4 metabolism. The modified composition may be coated with an enteric coating; and/or may comprise a solid dispersion or a solid solution of tacrolimus in a hydrophilic or water-miscible vehicle and one or more modifying release agents; and/or may comprise a solid dispersion or a solid solution of tacrolimus in an amphiphilic or hydrophobic vehicle and optionally one or more modifying release agents. | 2011-10-13 |
20110251233 | FORMULATION FOR THE BUCCAL TRANSMUCOSAL ADMINISTRATION OF SETRONS - The invention provides a formulation for transmucosal administration of at least one active ingredient from the setron family, the formulation comprising said active ingredient in base form and/or in salt form, a hydroalcoholic solution titrating at least 30° alcohol, and optionally a pH correcting agent, said active principle being present in the state of stable and complete dissolution in the hydroalcoholic solution. The invention also provides a method of preparing this formulation and its use for the treatment and prevention of major nausea and/or vomiting syndromes, and also for the treatment and prevention of digestive spasms. | 2011-10-13 |
20110251234 | MESYLATE SALT OF 5-(2--1-HYDROXYETHYL)-8-HYDROXYQUINOLIN-2(1H)-ONE AS AGONIST OF THE BETA2 ADRENERGIC RECEPTOR - The present disclosure relates to a mesylate salt of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one as well as pharmaceutical compositions comprising them, and their use in therapy as agonists of the β2 receptor. | 2011-10-13 |
20110251235 | STABLE LAQUINIMOD PREPARATIONS - The invention relates to a pharmaceutical composition comprising a pharmaceutically acceptable salt of N-ethyl-N-phenyl-1,2,-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide, N-methylglucamine, and a pharmaceutically acceptable carrier. | 2011-10-13 |
20110251236 | GALACTOKINASE INHIBITORS - Therapeutic agents for treatment of Galactosemia and disorders thereof, and other enzyme related disorders thereof are identified. The compounds inhibit galactokinase (GALK) and other kinase activity and are identified by a high throughput screening assay. | 2011-10-13 |
20110251237 | 2,5-Disubstituted Piperidine Orexin Receptor Antagonists - The present invention is directed to 2,5-disubstituted piperidine amide compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved. | 2011-10-13 |
20110251238 | PPAR AGONIST COMPOSITIONS AND METHODS OF USE - Method for treating or preventing a PPAR-responsive condition in a subject, comprising administering to the subject a PPAR agonist that comprises a 8-hydroxyquinoline-methylene-N- group in an amount effective to activate a PPAR polypeptide. | 2011-10-13 |
20110251239 | COMBINATION THERAPY FOR THE TREATMENT OF DEMENTIA - Provided herein is a combination therapy useful for the treatment of Alzheimer's disease and Alzheimer's disease related dementia. The combination comprises memantine in an immediate or sustained release form and donepezil in a sustained release form. | 2011-10-13 |
20110251240 | Dosing Regimen of Flavopiridol for Treating Cancer - A dosing regimen comprising a therapeutically effective amount of flavopiridol or a pharmaceutically acceptable salt thereof optionally in combination with a pharmaceutically acceptable carrier suitable for bolus infusion and subsequently for infusion is disclosed and claimed. Also disclosed and claimed is a method of treating a variety of cancers in a patient comprising administering to said patient the dosing regimen of the invention. | 2011-10-13 |
20110251241 | GREASE-LIKE GEL FOR REPELLING RODENTS - Grease-like compositions are provided for repelling rodents. The compositions utilize nontoxic mineral, synthetic, or vegetable oil based gels containing silica, clay, urea, polytetrafluoroethylene, or metallic soap thickeners and capsaicin. | 2011-10-13 |
20110251242 | PHOTOSTABILIZATION OF RESVERATROL WITH ALKOXYCRYLENE COMPOUNDS - The photostabilizing electronic excited state energy—particularly singlet state energy from resveratrol compounds—has been found to be readily transferred to (accepted by) α-cyanodiphenylacrylate compounds having an alkoxy radical in the four (para) position (hereinafter “alkoxycrylenes”) on one of the phenyl rings having the formula (I): | 2011-10-13 |
20110251243 | Method and Kit for Assessing a Patient's Genetic Information, Lifestyle and Environment Conditions, and Providing a Tailored Therapeutic Regime - A method of determining a personalised therapeutic regime, comprising: receiving genetic information relating to a patient; determining genetic criteria relevant to a personalised therapeutic regime for the patient using the genetic information; receiving personal information relating to the patient; determining personal criteria relevant to the personalised therapeutic regime using the personal information; and combining the genetic criteria and the personal criteria to determine the personalised therapeutic regime for the patient. | 2011-10-13 |
20110251244 | Oral Dosage Form Containing A PDE 4 Inhibitor As An Active Ingredient And Polyvinylpyrrolidone As Excipient - Dosage forms for oral administration of a PDE 4 inhibitor whose solubility is slight are described. They contain PVP as binder. | 2011-10-13 |
20110251245 | SOLID PHARMACEUTICAL COMPOSITION COMPRISING AMLODIPINE AND LOSARTAN - The present invention relates to a solid pharmaceutical composition for preventing or treating cardiovascular disorders comprising amlodipine and losartan as active ingredients, and a disintegrant which is a mixture of at least two components selected from the group consisting of sodium starch glycolate, crosscarmellose sodium, and crosspovidone, which exhibits a high and stable level of amlodipine and losartan dissolution rates. | 2011-10-13 |
20110251246 | SMALL MOLECULE INHIBITORS OF MUC1 AND METHODS OF IDENTIFYING THE SAME - The invention provides methods for the identification of small molecules that inhibit MUC1 oligomerization, and the functions flowing therefrom. In addition, small molecules that prevent MUC1 oligomerization are disclosed. Identified molecules will find use in treating a variety of MUC1-related inflammatory conditions, including MUC1-related cancers. | 2011-10-13 |
20110251247 | SUBSTITUTED ISOXAZOLINE DERIVATIVES - This invention recites substituted isoxazoline derivatives of Formula (1) | 2011-10-13 |
20110251248 | GLUCAGON RECEPTOR ANTAGONIST COMPOUNDS - Glucagon receptor antagonist compounds are disclosed. The compounds are useful for treating type 2 diabetes and related conditions. Pharmaceutical compositions and methods of treatment are also included. | 2011-10-13 |
20110251249 | DUAL-ACTING ANTIHYPERTENSIVE AGENTS - The invention relates to compounds having the formula: | 2011-10-13 |
20110251250 | USE OF DIMIRACETAM IN THE TREATMENT OF CHRONIC PAIN - The use of dimiracetam in the treatment of chronic pain is disclosed. At doses higher than those previously disclosed in relation with its cognition enhancing activity (i.e. amelioration of learning and memory), dimiracetam was able to completely revert hyperalgesia or allodynia associated with several animal models of chronic pain. Dimiracetam showed high activity in iatrogenic neuropathies associated with antiviral and chemotherapeutic drug treatments and in painful conditions caused by osteoarthritis. In addition, dimiracetam was devoid of toxicity even at doses 10-fold higher than the highest therapeutic dose. The possibility of treating such debilitating pathologies with a highly effective and essentially non-toxic compound is therefore disclosed. | 2011-10-13 |
20110251251 | POLYMORPH II OF AN ANTIFUNGAL COMPOUND - The invention relates to a crystalline polymorph of a pharmaceutically acceptable salt of an optically active anti-fungal imidazole compound of formula (III), the pharmaceutical and agricultural compositions containing such polymorph, its use in the treatment or prevention of skin or mucous membrane infections caused by fungi or yeasts in humans or pets, and its use in the treatment or prevention of agricultural diseases produced by such infectious agents. | 2011-10-13 |
20110251252 | BIOMARKERS FOR MDM2 INHIBITORS FOR USE IN TREATING DISEASE - Provided herein are methods for selecting and treating a subject with leukemia, wherein the subject is selected for treatment and is treated with an MDM2 inhibitor because said subject's cells contain an FLT3-ITD mutation. | 2011-10-13 |
20110251253 | SOLID FORMS OF (R)-1-(2,2-DIFLUOROBENZO[D][1,3]DIOXOL-5-YL)-N-(1-(2,3-DIHYDROXYPROPYL)-6- -FLUORO-2-(1-HYDROXY-2-METHYLPROPAN-2-YL)-1H-INDOL-5-YL) CYCLOPROPANECARBOXAMIDE - The present invention relates to solid forms of (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide (Compound 1) in substantially crystalline form (Form A) or amorphous form, pharmaceutical compositions thereof, and methods of treatment therewith. | 2011-10-13 |
20110251254 | NOVEL SALT OF TEGASEROD - The present invention relates to a novel salt of tegaserod, namely tegaserod suberate, and to processes for the preparation thereof. The invention also relates to crystalline forms of the novel salt and to pharmaceutical compositions comprising the novel salt. Further, the invention relates to uses of said compositions in treating patients suffering from gastrointestinal disorders. | 2011-10-13 |
20110251255 | Methods and Compositions for Inhibiting the Proliferation of Cancer Cells - A method of decreasing the expression of LIM kinase 1 in a cancer cell comprising; providing an oligonucleotide consisting of the sequence of SEQ ID NO: 1; providing a cancer cell comprising an mRNA encoding LIM kinase 1; and introducing the oligonucleotide into the cancer cell, wherein the oligonucleotide decreases the expression of LIM kinase 1 in the cancer cell. The method also provides compositions of an antisense RNA LIM kinase 1 that can be administered to an individual for the purpose of inhibiting a protein kinase pathway and which further comprises methods for treating and monitoring the proliferation and metastasis of cancer cells. A kit may be used in the detection and treatment of cancer. | 2011-10-13 |
20110251256 | USE OF TRIM72 AS A TARGET FOR MUSCLE AND HEART ENHANCER - The present invention relates to a new use of TRIM72 as a target for muscle enhancer and heart enhancer, more particularly to a composition for enhancing muscle or heart comprising an expression or action inhibitor of TRIM72 protein. The present invention further relates to a new TRIM mutant protein inducing muscle differentiation and hypertrophy and its gene. The inventors of the present invention have identified that TRIM72 overexpression inhibits myogenesis whereas TRIM72 knockdown enhances myogenesis, and first elucidated that TRIM72 is a negative regulator of skeletal muscle differentiation. Accordingly, the inhibition of TRIM72 acts exclusively on skeletal muscle and heart muscle, but does not affect IGF-I signaling pathway in other tissues. Therefore, a drug or gene therapy using TRIM72 as a target may be helpful in treating obesity and type 2 diabetes by promoting skeletal muscle differentiation, hypertrophy and energy consumption in adipose tissue and inducing strong muscle by promoting physiological hypertrophy of heart muscle, without cancer or other side effects. | 2011-10-13 |
20110251257 | METHODS AND COMPOSITIONS FOR TREATING NEUROLOGICAL DISEASE - This invention relates to methods and compositions for treating neurological disease, and more particularly to methods of delivering iRNA agents to neural cells for the treatment of neurological diseases. | 2011-10-13 |
20110251258 | RNAI CONSTRUCTS AND USES THEREOF - The invention relates to improved double-stranded RNAi constructs (sometimes referred to as “solo-rxRNA”) and uses thereof. The construct comprises a structure formed in some aspects of the invention by two identical single-stranded polynucleotides, with the structure having two double-stranded stem regions (each having less than 21 base pairs) and a loop or bulge having about 4 to 11 nucleotides on each strand. The construct is resistant to cleavage by Dicer or other Dicer-like RNase III enzymes and is capable of being loaded into a RISC complex to effect RNA interference. In addition, the nucleotides of the present hairpin constructs may be modified to greatly enhance functionality, such as stability and specificity. | 2011-10-13 |
20110251259 | COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF CD274/PD-L1 GENE - The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the CD274/PD-L1 gene, and methods of using such dsRNA compositions to inhibit expression of CD274/PD-L1. | 2011-10-13 |
20110251260 | NOVEL siRNAS AND METHODS OF USE THEREOF - The invention relates to compounds, in particular siRNAs, which inhibit the expression of specific human genes. The invention also relates to pharmaceutical compositions comprising such compounds and a pharmaceutically acceptable carrier. The present invention also provides a method of treating and/or preventing the incidence or severity of various diseases or conditions associated with the genes and/or symptoms associated with such diseases or conditions comprising administering to a subject in need of treatment for such disease or condition and/or symptom the compound or the pharmaceutical composition in a therapeutically effective dose so as to thereby treat the subject. The invention also provides antibodies which inhibit specified human polypeptides and pharmaceutical compositions comprising one or more such antibodies. | 2011-10-13 |
20110251261 | COMPOSITIONS AND METHODS FOR INHIBITION OF NUCLEIC ACIDS FUNCTION - The invention relates generally to compositions and methods for inhibiting the function of target nucleic acids by sequence specific binding. The compositions and methods can be used for inhibition of micro RNAs and other relatively short non-coding RNAs. | 2011-10-13 |
20110251262 | Compositions And Methods For Inhibiting Expression Of An RNA From West Nile Virus - This invention relates to double-stranded ribonucleic acid (dsRNA), and its use in mediating RNA interference to inhibit the expression of an RNA from the West Nile virus (WNV), and the use of the dsRNA to treat pathological processes mediated by WNV infection, such as viral encephalitis. | 2011-10-13 |
20110251263 | RNAi Modulation of the BCR-ABL Fusion Gene and Uses Thereof - The invention relates to compositions and methods for modulating the expression of Bcr-Abl, and more particularly to the down-regulation of Bcr-Abl mRNA and Bcr-Abl protein levels by oligonucleotides via RNA interference, e.g., chemically modified oligonucleotides. | 2011-10-13 |
20110251264 | TRANSCRIPTION FACTOR DECOYS - Methods and compositions for altering prokaryotic cellular viability phenotypes, including antibiotic susceptibility. | 2011-10-13 |
20110251265 | POLYAMINE-CONTAINING POLYMERS AND METHODS OF SYNTHESIS AND USE - The present invention relates to polyamine-containing polymers and methods of their synthesis and use. The polymer may be hydroxyethylcellulose, dextran, poly(vinyl alcohol) or poly(methyl acrylate). | 2011-10-13 |
20110251266 | APTAMER FOR NGF AND USE THEREOF - Provided are an aptamer having an inhibitory activity against NGF; a complex containing an aptamer having a binding activity or inhibitory activity against NGF and a functional substance (e.g., affinity substances, labeling substances, enzymes, drug delivery vehicles, drugs and the like); a medicament, a diagnostic agent, a labeling agent and the like containing an aptamer having a binding activity or inhibitory activity against NGF, or a complex containing the aptamer and the functional substance; and the like. | 2011-10-13 |
20110251267 | METHODS OF USING POLYNUCLEOTIDES ENCODING TRUNCATED GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR - Disclosed are novel proteins, referred to as truncated glial cell line-derived neurotrophic factor (truncated GDNF) proteins, that promote dopamine uptake by dopaminergic cells and promote the survival of nerve cells. Also disclosed are processes for obtaining the truncated GDNF proteins by recombinant genetic engineering techniques. | 2011-10-13 |
20110251268 | ANTIOXIDANT-CONTAINING FOOD COMPOSITION FOR USE IN INHIBITING HISTAMINE PATHWAYS IN COMPANION ANIMALS - The invention encompasses methods for inhibiting histamine release pathways in a companion animal, for example, felines and in treating or preventing idiopathic cystitis or interstitial cystitis. The compositions and methods of the invention include an amount of lipoic acid that is effective in inhibiting histamine release pathways in a companion animal, for example, felines and in treating or preventing idiopathic cystitis or interstitial cystitis. | 2011-10-13 |
20110251269 | PREPARATION METHOD OF POLYMERIC MICELLES COMPOSITION CONTAINING A POORLY WATER-SOLUBLE DRUG - Provided is a method for preparing a drug-containing polymeric micelle composition, which includes: dissolving a drug and an amphiphilic block copolymer into an organic solvent; and adding an aqueous solution to the resultant mixture in the organic solvent to form polymeric micelles, wherein the method requires no separate operation to remove the organic solvent prior to the formation of micelles. The method for preparing a drug-containing polymeric micelle composition is simple, reduces the processing time, and is amenable to mass production. | 2011-10-13 |
20110251270 | COMPOUNDS AND METHODS FOR REPELLING BLOOD-FEEDING ARTHROPODS AND DETERRING THEIR LANDING AND FEEDING - This invention relates to a group of compounds for repelling blood-feeding ectoparasitic arthropods, and a method of deterring their landing and feeding on animals including humans, by applying in one or more formulations compounds that incorporate one or more sulfide and one or more hydroxyl groups to the skin, clothing or environment of animals, including humans. A method of repelling and deterring landing and feeding by blood-feeding arthropods on an animal by applying in effective amount one or more compounds that incorporate alkyl sulfide and alcohol moieties, or alkyl sulfide and amide moieties, or alkyl sulfide and amide moieties to the skin, clothing or environment of an animal. | 2011-10-13 |
20110251271 | COSMETIC COMPOSITION WITH ANTI-FREE RADICAL ACTIVITY - Cosmetic compositions with anti-free radical activity have been developed. Such compositions preferably contain an association of at least the following three substances with anti-free radical activity: idebenone; N-acetylcysteine, and alpha-tocotrienol or an ester thereof with a C | 2011-10-13 |
20110251272 | METHODS AND COMPOSITIONS FOR PREDICTING DRUG RESPONSES - The present invention relates to methods and compositions for predicting drug responses. In particular, the present invention provides methods and compositions for determining individualized Warfarin dosages based on genotype of DNA polymorphisms and haplotypes derived from them in the VKORC1 gene. | 2011-10-13 |
20110251273 | COMPOSITION AND METHOD OF TREATING SKIN CONDITIONS - This invention relates to compositions containing a retinoid and use of the compositions for treating skin conditions. | 2011-10-13 |
20110251274 | Natural Vitamin E Compositions with Superior Antioxidant Potency - Compositions for increased antioxidant potency of natural vitamin E (d-alpha-tocopherol), comprising alpha-, beta-, delta-, and gamma-forms of tocopherols and tocotrienols are disclosed. All of these compositions provide 400 International Units (IU), based on one mg of d-alpha-tocopherol provides 1.49 IU. These compositions showed antioxidant activities superior to natural d-alpha-tocopherol. These compositions are designed to provide protection of the cell membrane lipid layer, and protection against heart disease, cancer, and eye disease. | 2011-10-13 |
20110251275 | OMEGA-3 FATTY ACIDS FOR REDUCTION OF LP-PLA2 LEVELS - Methods are provided for utilizing omega-3 fatty acids, or a combination of a dyslipidemic agent and omega-3 fatty acids, for the reduction of lipoprotein-associated phospholipase A | 2011-10-13 |
20110251276 | BIOLOGICAL OIL COMPOSITION, FORMULATIONS COMPRISING THE OIL COMPOSITION, AND USE THEREOF TO PREVENT OR TREAT CARDIOVASCULAR DISEASE - This invention relates to a biological oil composition, preferably obtained from a copepod, most preferably the copepod | 2011-10-13 |
20110251277 | FOAMED CLEANSER WITH SUSPENDED PARTICLES - One aspect of the invention is a new foam which includes a liquid having a plurality of bubbles therein and a plurality of particles suspended therein. The foam is made in a dispenser that suspends the bubbles in the liquid. The liquid may be a single liquid with particles therein or may be made from two liquids which are mixed together. The particles may be such that, prior to foaming the particles sink, float or are suspended in the liquid. | 2011-10-13 |
20110251278 | MICROALGAE EXTRACT CONTAINING OMEGA 3-POLYUNSATURATED FATTY ACIDS AND METHOD FOR EXTRACTING OIL FROM MICRO-ORGANISMS - The present invention relates to a biphasic microalgae extract comprising 15-95 wt. % of an aqueous phase and 5-85 wt. % of an oil phase, said extract containing at least 1% by weight of total fatty acids of ω3-fatty acids selected from the group consisting of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and combinations thereof, said extract further being characterized in that it contains: • 40-100% by weight of the oil phase of lipids selected from triglycerides, diglycerides, monoglycerides, phosphatides, free fatty acids and combinations thereof; • 0.01-10% of carotenoids by weight of the oil phase; • 0.5-10% of sodium chloride by weight of the aqueous phase; • 0-3 wt. % of non-dissolved material other than dispersed droplets of aqueous phase or oil phase; and • 0-10% of C | 2011-10-13 |
20110251279 | Composition of Amino Acids for Sublingual Applying for Enhanced Skin Integument Repigmentation in Vitiligo and Method of its Administration - The task of this invention is in use of composition containing natural metabolites—amino acids, and in method of its administration which make it possible to increase skin repigmentation through sulfurcontaining compounds rise and activation of endogenic metabolic reactions, and to get persistent normalization of melanogenesis thus improving skin integument and as a consequence patient's quality of life. | 2011-10-13 |
20110251280 | Stable Aqueous Compositions Comprising Amide-Protected Bioactive Creatine Species and Uses Thereof - The present invention provides amide-protected creatine molecules and compositions, containing one or more bioactive forms of creatine in aqueous compositions, wherein bioactive forms of creatine do not appreciably degrade into creatinine. Also provided are various beneficial effects of administering aqueous compositions having at least one amide-protected creatine molecule. | 2011-10-13 |
20110251281 | Composite Material Comprising High-Molecular-Weight Matrix and Low-Molecular-Weight Organic Compound and Process For Producing Same - Previously reported composite materials comprising a hydrophilic high-molecular-weight matrix and a low-molecular-weight organic compound involve a problem in that: it is difficult to compound a high load of the low-molecular-weight organic compound in the high-molecular-weight matrix; and thus produced composite material yields a high-molecular-weight matrix component that can form a thrombus when contacting with blood. Now, it becomes possible to produce a composite material having an antithrombogenic activity and a high content of a low-molecular-weight organic compound by the present invention comprising the steps of: crosslinking a polymer with an organic acid derivative which is used as a crosslinker in an organic solvent while at the same time embedding the low-molecular-weight organic compound therein; and substituting the organic solvent by water after the production of the high-molecular-weight matrix to effect precipitation and compounding of the low-molecular-weight organic compound in the high-molecular-weight matrix. | 2011-10-13 |
20110251282 | LIQUID COMPOSITIONS OF CALCIUM ACETATE - The invention relates to an aqueous liquid composition of calcium acetate, sweetener, and taste masking agent. Also provided is a method for binding phosphorus within the gastrointestinal tract of an individual by administering to the individual an aqueous solution of at least calcium acetate. | 2011-10-13 |
20110251283 | 1-AMINO-ALKYLCYCLOHEXANE DERIVATIVES FOR THE TREATMENT OF MAST CELL MEDIATED DISEASES - The present invention relates to the treatment of an individual afflicted with mast cell mediated diseases comprising administering to the individual an effective amount of a 1-amino-alkylcyclohexane derivative. | 2011-10-13 |
20110251284 | HALO ACTIVE AROMATIC SULFONAMIDE ORGANIC COMPOUNDS AND USES THEREFOR - Aromatic N-halosulfonamide organic compounds have been known for over one hundred years. The ability of these compounds to release active halogen ions has been utilized in a range of biocidal and fungicidal applications. This disclosure deals with the use of halo active aromatic sulfonamide organic compounds as odor control and/or biocidal agents in a cleaning solution for use with bovines and other dairy animals. | 2011-10-13 |
20110251285 | COMBINATIONS OF PRESERVATIVES FOR OPHTHALMIC COMPOSITIONS - The present invention provides a preservative composition for protecting ophthalmic solutions from microbial attack comprising a combination of benzalkonium ion and polyhexamethylene biguanide (PHMB) wherein the combined concentrations of benzalkonium ion and polyhexamethylene biguanide (PHMB) in said composition is sufficient to provide protection against microbial attack when said composition is added to an ophtalmic solution as compared to said ophthalmic soulution having the same concentration of benzalkonium ion and polyhexamethylene biguanide (PHMB), alone. | 2011-10-13 |
20110251286 | Crystalline salts and/or co-crystals of O-desmethyltramadol - Salts and/or co-crystals of (+)-3-[2-(dimethylamino)-methyl-1-hydroxycyclohexyl]-phenol or of (−)-3-[2-(dimethylamino)methyl-1-hydroxy-cyclohexyl]phenol, present in crystalline form, with cinnamic acid, C | 2011-10-13 |
20110251287 | HCI POLYMORPHS OF 3-((2-(DIMETHYLAMINO)METHYL (CYCLOHEX-1-YL))PHENOL - A crystalline salt of 3-[2-(dimethylamino)methyl(cyclohex-1-yl)]phenol and hydrogen chloride, preferably in a 1:1 composition, including various crystalline forms of this salt, processes for preparing the various crystalline forms of this salt, pharmaceutical compositions containing the various crystalline forms of this salt, and the use of this salt as a pharmacologically active agent in a pharmaceutical composition to treat or inhibit pain or other disorders or disease states. | 2011-10-13 |
20110251288 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE AMINES - The present invention relates to an improved process for the preparation of (R)-1-aminoindan (2), rasagiline (1) and pharmaceutically acceptable salts of rasagiline. | 2011-10-13 |
20110251289 | NEW COMPOUNDS FOR THE TREATMENT OF CANCER - The invention provides a method of preparing the stereoisomers of 1,11-diamino-6-aza-undecane-2,4,8,10-tetraol. | 2011-10-13 |
20110251290 | TREATMENT OF HEPATIC ENCEPHALOPATHY AND LIVER CIRRHOSIS - The compounds D9-tetrahydrocannabinol (THC), cannabidiol (CBD) and capsaicin are useful for prevention, treatment, or both, of hepatic encephalopathy. The compounds capsaicin, 2-arachidonoylglycerol (2-AG), HU-308 and cannabidiol are useful for prevention, treatment, or both, of liver cirrhosis. | 2011-10-13 |
20110251291 | Topical Compositions Containing CIS-6-Nonenol and its Derivatives and Methods for Treating Skin - Cosmetic compositions comprising cis-6-nonenol and methods of using such compositions to impart anti-aging benefits to the skin are disclosed. Cis-6-nonenol is believed to have modulatory activity against at least one biochemical pathway implicated in skin aging. | 2011-10-13 |
20110251292 | MIXTURE AND METHOD FOR CONTROLLING THE INSECT ACROBASIS NUXVORELLA ON CARYA ILLINOIENSIS PLANTS - The invention consists of a mixture of organic chemicals avoiding the use of insecticides, and a method for pest control based on the mixture consisting in bringing about the premature eclosion of the hibernating larva and its possible death through inanition; experimentation has demonstrated it to be effective in bringing about the premature eclosion of the pecan nut casebearer or | 2011-10-13 |
20110251293 | COLOURED GLASS PARTICLES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF - Glass particles colored with at least one colorant, where the colored glass particles are glass platelets with an average diameter of 1 to 500 μm and the colorants comprise or consist of at least one of metallic nanoparticles and metal oxides. The glass platelets are planar and the colorants are present in a concentration from 1% to 55% by weight, based on the total weight of the colored glass platelets. The disclosure further relates to a method for producing the colored glass particles and to the use thereof. | 2011-10-13 |
20110251294 | FAST RECOVERY OF THIXOTROPY BY ORGANOGELS WITH LOW MOLECULAR WEIGHT GELATORS - Low molecular weight gelators, methods of making such gelators, organogels comprising such gelators and methods of using such organogels are described. In exemplary methods, the gelators can be used in a variety of applications including the delivery of pharmaceutical active pharmaceutical ingredients, in food, cosmetics and consumer products, and in containing the unexpected release of chemical that occur for example in spills. | 2011-10-13 |
20110251295 | Electronic Grade Metal Nanostructures - Methods for producing electronic grade metal nanostructures having low levels of contaminants are provided. Monolayer arrays, populations, and devices including such electronic grade nanostructures are described. In addition, novel methods and compositions for production of Group 10 metal nanostructures and for production of ruthenium nanostructures are provided, along with methods for recovering nanostructures from suspension. | 2011-10-13 |
20110251296 | PRE-EXPANDED PARTICLES, PROCESS FOR PRODUCING THE SAME, AND EXPANDED MOLDED ARTICLE - A process for producing pre-expanded particles, comprising the steps of:
| 2011-10-13 |
20110251297 | WATER-BLOWN RIGID FOAMS WITH IMPROVED MECHANICAL PROPERTIES AT LOW TEMPERATURES - The present invention relates to a rigid polyurethane foam which can be obtained by mixing (a) isocyanates, (b) compounds having groups which are reactive toward isocyanates, (c) blowing agents comprising water, (d) catalysts and optionally (e) further additives to form a reaction mixture, applying the reaction mixture to a reinforcing material and curing the reaction mixture, where the isocyanates (a) have a viscosity of not more than 500 mPas at 25° C. and the compounds (b) having groups which are reactive toward isocyanates comprise a polyetherol (b1) having a functionality of 4 or more and a viscosity at 25° C. of 10 000 mPas or less, a polyetherol (b2) having a functionality of 3.5 or less and a viscosity at 25° C. of 600 mPas or less, a polyesterol (b3) having a viscosity at 25° C. of 2000 mPas or less, chain extenders (b4) comprising at least 30% secondary OH groups and optionally a crosslinker (b5). The present invention further relates to a process for producing such rigid polyurethane foams and the use of the rigid polyurethane foams for the insulation of liquefied natural gas tanks. | 2011-10-13 |
20110251298 | RADIATION-CURABLE INK COMPOSITION, INK JET RECORDING METHOD, AND RECORDED MATTER - A radiation-curable ink composition contains (A) aminoacrylate at 1 mass % to 10 mass %, inclusive, (B) phenoxyethyl acrylate at 20 mass % to 50 mass %, inclusive, and (C) tetraethylene glycol diacrylate at 1 mass % to 20 mass %, inclusive, in its reaction component, as well as (E) bis(2,4,6-trimethylbenzoyl)-phenylphosphine oxide at 3 parts by mass to 8 parts by mass, inclusive, (F) 2,4,6-trimethylbenzoyl-diphenyl-phosphine oxide at 3 parts by mass to 5 parts by mass, inclusive, in 100 parts by mass of the reaction component, and (G) diethylthioxanthone at 1 part by mass to 3 parts by mass, inclusive, in 100 parts by mass of the reaction component. | 2011-10-13 |
20110251299 | PHOTO-ENFORCED STRATIFICATION OF POLYMERIC MATERIALS - The invention provides a process for manufacturing a polymeric material having a compositional gradient, comprising: forming a mixture comprising a first photopolymerizable polymer precursor and a second photopolymerizable precursor, and subjecting said mixture to an intensity gradient of electromagnetic radiation, wherein said first precursor has a greater reactivity ratio than said second precursor, and/or said first precursor is mono-functional and said second precursor is di-functional, and/or said first precursor is less inhibited by oxygen than said second precursor. | 2011-10-13 |
20110251300 | SOFT SHAPEABLE ADHESIVE PASTE - The present invention relates to a pressure sensitive paste composition for skin application. The paste comprises 10-50% (w/w) based on the total paste formulation of a blend of polar polyethylene copolymer(s) and polar oil. | 2011-10-13 |
20110251301 | POLYMERIZABLE LIQUID COMPOSITION AND PROCESS FOR THE PRODUCTION OF ORGANIC GLASS STARTING FROM POLYMERIZABLE LIQUID COMPOSITIONS OF THE POLYURETHANE TYPE - Polymerizable liquid compositions of the polyurethane type, consisting of two components (A) and (B), wherein component (A) contains at least one cyclo-aliphatic diisocyanate monomer or a mixture of one cyclo-aliphatic diisocyanate monomer and a pre-polymer obtained by reaction, in the presence of an acid phosphate ester catalyst, between said cyclo-aliphatic diisocyanate monomer and one or more polyols having two or more hydroxy 1 groups per molecule and a molecular weight ranging from 50 to 2,000 g/mole; the second component (B) contains one or more polyols having a molecular weight ranging from 50 to 2,000 g/mole and a functionality between 2 and 5; in the absence of polyalkoxylated tertiary diamines and organometallic catalysts, said components (A) and (B) being present in a weight ratio which varies from 1:1 to 2:1 and the process for the production of organic glass starting from polymerizable liquid compositions of the polyurethane type. | 2011-10-13 |
20110251302 | Mixtures, Compositions, and Methods of Applying Mixtures as Coatings - Mixtures are provided that can include: latex polymer; antifoam; surfactant; plasticizer; ether; fungicide; glycol; and liquid stabilizer. Mixtures comprising: glycol; antioxidant; and defoamer. Compositions are provided that can include: a substrate; and a mixture over the substrate, the mixture comprising one or more of: latex polymer; antifoam; surfactant; plasticizer; ether; fungicide; glycol; liquid stabilizer; and antioxidant. Vehicle tires are provided. Plastic vehicle components are provided. Substrate treatment methods are provided that can include applying compositions to the substrate, the compositions comprising one or more of: latex polymer; antifoam; surfactant; plasticizer; ether; fungicide; glycol; liquid stabilizer; and antioxidant. Vehicle tire treatment methods are provided. Vehicle component treatment methods are provided. | 2011-10-13 |
20110251303 | PIGMENT GRANULES - Pigment granules comprise one or more flake-form effect pigments, polymer particles or polymer particle mixtures, adhesion promoters, antioxidants and optionally additives. A process for the preparation of pigment granules comprises mixing one or more flake-form effect pigments, one or more polymer particles, at least one adhesion promoter, at least one antioxidant and optionally one or more additives with one another simultaneously or successively. The pigment granules may be used for the pigmentation of powder coatings, plastics and for the preparation of masterbatches. The pigment granules may be employed as a mixture with plastic powders or as a mixture with plastic granules for use in masterbatch applications. | 2011-10-13 |
20110251304 | OPACIFYING PARTICLES AND COMPOSITIONS FORMED THEREFROM - An opacifying particle including a pigment particle having an average particle diameter of from 0.15 micron to 1.0 micron and a refractive index of at least 1.8, the pigment particle being at least partially encapsulated in a polymeric shell having a calculated thickness of from 35 nm to 200 nm, wherein the polymeric shell includes at least a first polymer phase and a second polymer phase, wherein the first polymer is substantially in contact with the surface of the pigment particle providing a calculated shell thickness of at least 25 mm. and wherein the first polymer has a refractive index of at least 0.03 units less than the refractive index of the second polymer is provided as is a composition such as, for example, a coating or a plastic including the opacifying particle. Further provided is a composition including pigment particles having an average particle diameter of from 0.15 micron to 1.0 micron and a refractive index of at least 1.8, the pigment particles being at least partially encapsulated in a shell of a first polymer having a calculated thickness of from 25 nm to 200 nm, and the encapsulated pigment particles in contact with from 10% to 600% by weight, based on the weight of the first polymer, second polymer, wherein the first polymer has a refractive index of at least 0.03 units less than the refractive index of the second polymer. | 2011-10-13 |
20110251305 | EPOXY COMPOSITION FOR ENCAPSULATING AN OPTICAL SEMICONDUCTOR ELEMENT - The present invention has a purpose of providing an epoxy composition for encapsulating an optical semiconductor element which composition provides a cured product having a low gas permeability and excellent curability in a form of a thin film together with good light transmission and crack resistance. The present invention provides a composition comprising (A) a silicone-modified epoxy compound represented by the formula (1), (B) a curing agent and (C) a polyhydric alcohol. The present invention further provides a composition comprising a composition prepared by reacting (A) the silicone-modified epoxy compound, (B) the curing agent and (C) the polyhydric alcohol and (D) a curing catalyst, and a cured product thereof. | 2011-10-13 |
20110251306 | WAX BLENDS FOR USE WITH ENGINEERED WOOD COMPOSITES - Wax is a key ingredient in engineered wood composites, such as oriented strand board (OSB) and oriented strand lumber (OSL), to prevent and reduce swelling caused by water uptake. Wax, normally a byproduct of oil refining and lube production, is now considered a precious feedstock for producing higher margin product such as fuel or diesel. Disclosed herein are suitable alternative waxes to petroleum wax for use as sizing agents in producing engineered wood composites. | 2011-10-13 |
20110251307 | USE OF A STYRENE LATEX 100 NM IN SIZE AS A RHEOLOGICAL AGENT IN A PAPER COATING, THE PAPER COATING, AND THE METHOD FOR OBTAINING IT - The invention relates to coating slip including latex comprising styrene and with a particle size centered around 100 nm, the use of latex as an agent for reducing the low shear gradient viscosity and increasing the low shear gradient viscosity, and methods thereof. | 2011-10-13 |
20110251308 | FUNCTIONALIZED MULTI-ARM POLYMERS WHICH COMPRISE FUNCTIONALIZED POLYMERS SYNTHESIZED BY ANIONIC POLYMERIZATION AND THEIR APPLICATIONS - Functionalized multi-arm polymers which comprise the reaction product of a coupling agent and a polymer synthesized by anionic polymerization. Furthermore, the invention relates to their preparation method and their different uses, especially as hot-melt adhesives. | 2011-10-13 |
20110251309 | BRANCHED MELT POLYCARBONATE WITH LOW CONTENT OF DEFECTIVE STRUCTURES - The present invention relates to an aromatic branched polycarbonate, produced via melt transesterification of a bisphenol with a diaryl carbonate in the presence of a branching agent, wherein the aromatic branched polycarbonate comprises branching point structures and structures of formula (D) | 2011-10-13 |
20110251310 | Hydrophosphorylation of Phosphonous Acid Derivatives for Flame Retardants - The invention relates to addition compounds of a) alkylphosphonous acid derivatives of the formula A-P(═O)(OX)—H (I) in which A represents C | 2011-10-13 |
20110251311 | ADDITION CURABLE SELF-ADHESIVE SILICONE RUBBER COMPOSITION - An addition curable self-adhesive silicone rubber composition comprising (A) an organopolysiloxane containing at least two alkenyl groups, (B) an organohydrogenpolysiloxane containing at least three SiH groups, (C) an aromatic ring-free organohydrogenpolysiloxane containing at least two SiH groups, and (F) an addition reaction catalyst, with a SiH/alkenyl molar ratio ranging from 0.8 to 5.0, is briefly moldable and cures to various metals and organic resins. | 2011-10-13 |
20110251312 | Process for Preparing Ethylenedialkylphosphinic Acids, Esters and Salts by Means of Acetylene and Use Thereof - The invention relates to a process for preparing ethylenedialkylphosphinic acids, ethylenedialkylphosphinic esters and ethylenedialkylphosphinic salts, characterized in that a) a phosphinic acid source (I) is reacted with olefins (IV) in the presence of a catalyst A to give an alkylphosphonous acid, its salt or ester (II), b) the resultant alkylphosphonous acid, its salt or ester (II) is reacted with an acetylenic compound (V) in the presence of a catalyst B, to give the ethylenedialkylphosphinic acid derivative (III), where R | 2011-10-13 |
20110251313 | Phosphonate Compound and Flame Retardant Styrenic Resin Composition Including the Same - The present invention provides phosphonate compounds represented by Chemical Formula 1. In addition, the invention provides flame retardant styrene resin compositions comprising (A) styrene resin, (B) polyphenylene ether resin, and (C) the phosphonate compound. The flame retardant styrene resin compositions according to the invention: can provide protection against fire, exhibit improved impact strength, and can be environment-friendly. | 2011-10-13 |
20110251314 | Method for the Production of Alkylphosphonic Acids, Esters, and Salts by Oxidizing Alkylphosphonous Acids, and Use Thereof - The invention relates to a method for producing monocarboxy-functionalized dialkylphosphinic acids, esters, and salts, characterized in that a) a phosphinic acid source (I) is reacted with olefins (IV) in the presence of a catalyst A to obtain an alkylphosphonous acid, the salt or ester (II) thereof, and b) the obtained alkylphosphonous acid, the salt or ester (II) thereof is reacted with an oxidizing agent or with an oxidizing agent and water or with oxygen and water in the presence of a catalyst B to obtain the alkylphosphonic acid derivative (III), wherein R | 2011-10-13 |
20110251315 | Method for the Production of Monofunctionalized Dialkylphosphinic Acids, Esters and Salts, and Use Thereof - The invention relates to a method for producing monofunctionalized dialkylphosphinic acids, esters, and salts, characterized in that a phosphinic acid source (I) is reacted with olefins (IV) in the presence of a catalyst A to obtain an alkylphosphonous acid, the salt or ester thereof, whereupon said alkylphosphonous acid, the salt or ester (II) thereof is reacted with compounds containing C═C, C═O, or C═N double bonds to obtain compounds of type (III), wherein R | 2011-10-13 |
20110251316 | FLAME RETARDANT POLYCARBONATE COMPOSITIONS - The present invention relates to impact-modified polylactic acid/polycarbonate compositions, containing
| 2011-10-13 |
20110251317 | Aqueous Polymerization of Fluorinated Monomer Using Polymerization Agent Comprising Fluoropolyether Acid or Salt and Short Chain Fluorosurfactant - A process comprising polymerizing at least one fluorinated monomer in an aqueous medium containing initiator and polymerization agent to form an aqueous dispersion of particles of fluoropolymer, the polymerization agent comprising:
| 2011-10-13 |
20110251318 | ADHESIVE COMPOSITION - An adhesive composition is provided particularly excellent in thermal shock resistance for adhesive strength as well as high shear adhesive strength, peel adhesive strength and impact adhesive strength. The adhesive composition of the present invention contains (a) a 2-cyanoacrylate such as 2-ethoxyethyl 2-cyanoacrylate and (b) a polyfunctional cyanoacrylate having two or more 2-cyanoacryloyl groups, the number average molecular weight of the polyfunctional cyanoacrylate (b) is in the range from 1,000 to 50,000, and preferably from 2,000 to 30,000, and the content of the polyfunctional cyanoacrylate (b) is in the range from 1 to 400 parts by weight, and preferably from 1 to 200 parts by weight based on 100 parts by weight of the 2-cyanoacrylate (a). | 2011-10-13 |
20110251319 | DIELECTRIC PASTE COMPOSITION, METHOD OF FORMING DIELECTRIC LAYER, DIELECTRIC LAYER, AND DEVICE INCLUDING THE DIELECTRIC LAYER - A dielectric paste composition including: a plurality of inorganic dielectric particles, a binder, a solvent, and a halogenated hydrocarbon. Also disclosed is a method of forming a dielectric layer, a dielectric layer, and a device including the dielectric layer. | 2011-10-13 |
20110251320 | NOVEL ELASTOMERIC COMPOSITIONS WITH IMPROVED HEAT RESISTANCE, COMPRESSION SET, AND PROCESSABILITY - An elastomeric composition containing a rubber polymer, an acid acceptor, and a silane-modified needle-like/acircular mineral additive. Compositions according to the present invention have superior heat resistance, compression set resistance, and improved processability (lower compound Mooney) compared to known rubber compositions. | 2011-10-13 |
20110251321 | Silicone Gel-Forming Compositions and Hysteretic Silicone Gel and Device Comprising the Gel - There is provided silicone gel-forming composition comprising a unique combination of polyorganosiloxane and organohydrogenpolysiloxane, which can produce silicone gel with improved hysteresis. | 2011-10-13 |
20110251322 | NON-BENZENE ADHESIVE AND MANUFACTURING PROCESS THEREOF - The present invention relates to a non-benzene adhesive and a manufacturing process thereof. The process includes: mixing a mixed solvent including 50 wt % of methylcyclohexane (MCH), 30 wt % of n-propyl acetate (NPAC) and 20 wt % of methyl ethyl ketone (MEK) with a first natural rubber, then mixing the mixture with a monomer under a heating condition; adding a thermal initiator to carry out a thermal polymerization reaction; stopping the thermal polymerization reaction with a terminator; adding a vulcanization accelerator after cooling down to produce a liquid semi-finished product; subsequently firstly mixing the semi-finished product with the MCH and the NPAC, then adding a second natural rubber; and continuously and successively adding the NPAC while maintaining a stirring and flowing state, so as to produce an industrial non-benzene adhesive including no benzene components for applying in pasting different kinds of shoes, without compromising the stickiness of the adhesive. | 2011-10-13 |
20110251323 | COMPOSITION FOR FORMING RESIST LOWER LAYER FILM - A composition for forming a resist lower layer film, which contains (A) a resin, (B) a butyl ether group-containing crosslinking agent and (C) a solvent. | 2011-10-13 |
20110251324 | Composition - A composition for use in injection molded protective articles including:
| 2011-10-13 |
20110251325 | RECYCLED THERMOPLASTIC COMPOSITIONS - A thermoplastic composition comprising recovered poly(arylene ether), less than or equal to 0.1 weight percent based on the total weight of the thermoplastic composition of a second recovered thermoplastic that gives off greater than or equal to 10 percent by mass of volatiles at a processing temperature for the thermoplastic composition; 0.025 to 4.0 weight percent, based on the total weight of the thermoplastic composition, of a third recovered thermoplastic selected from the group consisting of polyolefin, acrylonitrile-butadiene-styrene, polycarbonate, polycarbonate/acrylonitrile-butadiene-styrene blend, polymethyl methacrylate, polyamide, polyester, polycarbonate/polyester blend and combinations of two or more of the foregoing third recovered thermoplastics, wherein combinations of two or more of the foregoing third recovered thermoplastics are present in an amount of less than or equal to 10 weight percent, based on the total weight of the thermoplastic composition; and an optional virgin thermoplastic. | 2011-10-13 |
20110251326 | AROMATIC POLYCARBONATE COMPOSITION - The present invention relates to a polymer composition containing the following components: a) 30-97 mass % of aromatic polycarbonate, b) 0.5-20 mass % of a metal compound capable of being activated by electromagnetic radiation and thereby forming elemental metal nuclei, and c) 2.5-50 mass % of at least one rubber-like polymer, wherein the sum of a)-c) is 100%. | 2011-10-13 |
20110251327 | Antistatic White Coating with a Hydroxylated Acrylic Base - An antistatic white paint suitable for application on spacecraft notably, based on a binder of the acrylic polymer type. | 2011-10-13 |