41st week of 2011 patent applcation highlights part 40 |
Patent application number | Title | Published |
20110251027 | Exercise Apparatus - An exercise apparatus comprising a clamping assembly, one or more adjustment plates, one or more pivot plates, and a weight bearing assembly is provided. The clamping assembly comprises claw members, each comprising a vertical web and horizontal flanges extending from the vertical web. The horizontal flanges detachably clamp to a support structure. The adjustment plates are rigidly attached to the vertical web of one of the claw members and comprise apertures for enabling positional adjustment of the weight bearing assembly. The pivot plates are rigidly attached to the vertical web of another one of the claw members. The weight bearing assembly comprises a leg member rigidly attached to a support frame, and gripping handles. The leg member is pivotally connected to the pivot plates and detachably connected to the adjustment plates. The gripping handles that are rigidly supported by the support frame are held by a user for performing exercises. | 2011-10-13 |
20110251028 | Exercise Apparatus - An exercise apparatus comprising an elongate support member, an exercise attachment, a frame member, and lateral arm supports is provided. The elongate support member is removably attached to a support frame of the exercise apparatus. The exercise attachment, for example, a rod member, a strapping element, etc., is connected to a lower end of the elongate support member via a pulley system for supporting the user's arms and/or legs. The pulley system comprises a first pulley connected to the lower end of the elongate support member, and a cable rollably attached to the first pulley. The frame member is rigidly attached to the elongate support member. The lateral arm supports are rigidly attached on opposing sides of the frame member. The lateral arm supports extend outwardly from the frame member for supporting the user's arms. The user utilizes the exercise attachment and/or the lateral arm supports for performing an exercise. | 2011-10-13 |
20110251029 | EXERCISE DEVICE WITH SUSPENDED INERTIAL CORE - An inertial exercise device includes a hollow outer ball and a weighted inner ball elastically suspended inside the outer ball by at least two opposing suspension members. The weighted innerball may contain a fluid mass. The hollow outer ball, the weighted inner ball and the at least two opposing suspension members may all be integrally formed with each other. In one embodiment, the outer ball, the inner ball, and the suspension members are all formed from integral segments of a pliant tube. The hollow outer ball is formed by everting first and second end segments of the tube over the middle segment of the tube and joining the first and second end segments of the tube together at their openings. The weighted inner ball is formed from the middle segment of the tube which, in one embodiment, is a bulge in the tube. | 2011-10-13 |
20110251030 | EXERCISE DEVICE - An exercise device is disclosed having a main body including a material chamber formed therein. A flowable material is disposed within the material chamber and a level indicator is coupled to the main body. The exercise device is grasped by user. The flowable material and the level indicator provide sensory feedback to the user in respect of maintaining the exercise device in a substantially level position while in use. | 2011-10-13 |
20110251031 | DYNAMIC BALANCE REFORMER EXERCISE APPARATUS - A reformer exercise apparatus is disclosed that has a generally rectangular frame with a head end and a foot end and parallel spaced tracks therebetween supporting a movable carriage thereon. The frame includes a foot support at the foot end of the frame and one or more elastic resistance members fastened between the carriage and the foot end of the frame. Supporting the frame is a first rocking support assembly supporting the head end of the frame and a second rocking support assembly supporting the foot end of the frame, whereby the frame can rock from side to side to provide a dynamic feedback to a user of the apparatus as to whether or not the user is properly centered on the apparatus. A kit for changing a conventional reformer into a rocking reformer apparatus is also disclosed. | 2011-10-13 |
20110251032 | EXERCISE APPARATUS AND METHOD THEREFOR - The total body exercise apparatus comprises a unique movable structure to provide resistance for a variety of exercises. In one or more embodiments, the exercise apparatus comprises arms rotatably secured via a joint that allows the arms to provide resistance in virtually any direction. The exercise apparatus utilizes this capability to resist motions of various exercises and body motions to tone and strengthen a user's muscles. The resistance provided may be adjustable by an adjustable resistance assembly or by a cuff and socket assembly that applies variable force to a spherical head of the joint of the exercise apparatus. | 2011-10-13 |
20110251033 | MULTI-PLANAR RESISTANCE BAND EXERCISE SYSTEM - The present invention describes a portable resistance band exercise system used for training muscles, which may be used in a multi-planar workout routine, allowing various muscle groups to be exercised simultaneously. The user attaches each of one or more body attachment fasteners to one or more resistance bands, which are in turn attached to attachment points on a board. The attachment points are arranged in a semi-circular orientation on the board. The board may be used horizontally or upright, to permit a variety of exercises to be performed. Said exercise system also employs an ankle strap which has bumpers to cushion the user's shin and a foot strap to prevent the ankle strap from sliding up the user's lower leg. | 2011-10-13 |
20110251034 | Total body strengthening toning workstation and method of using same - A stand-alone exercise apparatus includes a seat to support a user in a position thereon, and upper and lower body exercising assemblies which are configured for activation either sequentially or simultaneously to permit the concurrent exercising movement of his or her upper body area and lower body leg muscles, respectively, without necessitating that the user stop exercising when switching from upper body exercises to lower body exercises. The lower body exercising assembly includes a lower frame assembly which is operable to provide resistance exercise to the user's leg muscles, and which includes a selectively reciprocally movable pedal, platform or bar which is coupled to a suitable resistance mechanism, and which is engagable by the user's feet and/or legs as they are moved together in unified movement to effect leg extensions or curls. The upper body exercising assembly includes one or more reciprocally movable frame members, hand pulleys or swing arms coupled to a resistance mechanism, and which are engagable by the user's hands and/or arms. The resistance mechanisms used to provide the selected resistance to the upper and lower exercising assemblies are operable independently from each other, and enable the user to select the degree of resistance to each of the upper and lower body exercising assemblies separately. | 2011-10-13 |
20110251035 | TOOL CHAIN MAGAZINE - A tool chain magazine, in particular for program-controlled milling machines and machining centers, comprising a stationary supporting structure to which linear guiding devices, chain wheels, and a drive assembly as a rotary drive for at least one of the chain wheels are mounted. The tool chain comprises an endless magazine chain consisting of a series of chain links connected in an articulate manner to one another, wherein supporting and guiding elements are provided on each chain link, and each chain link has a respective socket as a holder for a tool taper. The base bodies of the chain links of the magazine chain are formed by the tool stations centrally disposed therein, and the front and rear connecting joints of the chain links are arranged in the longitudinal center axis of the magazine chain. | 2011-10-13 |
20110251036 | Apparatus For Repairing A Vibration Roller - The present invention relates to an apparatus for repairing a vibration roller or a similar rotational tool, the outside jacket of which has been worn out up to a wear limit, comprising at least two repair segments which are arranged especially in their inside geometry in an at least partly complementary way with respect to the outside jacket and can be placed on the same by forming a repair jacket. | 2011-10-13 |
20110251037 | Methods and Apparatus for Prepaid Card Packaging - Techniques for providing cost effective and tamper evident prepaid card packaging are described. By forming a cutout in a panel of the prepaid card packaging, covering the cutout with a material such as red glassine, and aligning an activation bar code or other indicia on the card with the cutout when mounting the card within the packaging, the security of the activation indicia can be better maintained. After purchase, the bar code can be scanned through the red glassine but prior to purchase, the red glassine prevents photocopying. | 2011-10-13 |
20110251038 | Methods and Apparatuses for Tucking Side Panels of Absorbent Articles - Aspects of the present disclosure relate to tucking opposing side panels into a chassis of a diaper pant. The apparatuses and methods may utilize one or more conveyors that advance the chassis along a machine direction. Each conveyor may have a vacuum zone that applies a vacuum force to hold the chassis. The chassis may be positioned between a first conveyor having a first vacuum zone and a second conveyor having a second vacuum zone. The conveyors may apply opposing vacuum forces to hold the first waist region apart from the second waist region while the chassis advances in the machine direction toward a tucking device. The vacuum forces are then removed from the waist regions as the tucking device pushes the side panels toward each other. Pushing the side panels toward each other causes the inner surfaces of the waist regions to simultaneously move toward each other. | 2011-10-13 |
20110251039 | KNEE AIRBAG AND METHOD OF FOLDING THE SAME - A method of folding a knee airbag. One side surface of the airbag is roll-folded toward the centerline defined by the airbag and the other the side surface is thereafter roll-folded toward the centerline. After the steps of roll-folding both of the side surfaces, the knee airbag is vertical roll-fold from an end toward a connection part. With the roll-folding of the side surfaces, the side surfaces are roll folded such that they form different inclination angles with respect to the centerline of the airbag. | 2011-10-13 |
20110251040 | Apparatuses and Methods for Folding an Absorbent Article - Aspects of the present disclosure involve methods and apparatuses for folding absorbent articles. | 2011-10-13 |
20110251041 | Method and Apparatus for Separating a Material - A separation system for separating a multiple component material into at least two fractions. The separation system includes a separation device having a first end, a second end opposite to the first end, and a sidewall that extends between the first end and the second end to define a separation chamber having an interior volume. The system also includes a valve moveable between an open position and a closed position, the valve is mounted at a fixed location within the separation chamber at a position that is closer to the second end than to the first end and is spaced apart from the second end, the valve is operable to isolate a first fraction of the multiple component material having a first density on a first side of the valve from a second fraction having a second density on a second side of the valve that is opposite to the first side. | 2011-10-13 |
20110251042 | ALUMINA SINTERED BODY - An alumina sintered body of the present invention has alumina crystals as a main phase and an amorphous grain boundary glass phase. The amorphous grain boundary glass phase is a grain-boundary glass phase having an amorphous glass component in which at least one of either CaO or MgO is added to SiO | 2011-10-13 |
20110251043 | MINERAL WOOL FROM RECYCLABLE MATERIALS - Provided is a mineral wool that includes recycled material. The mineral wool is characterized by an acid to base ratio within a specified range. Also provided is a method of manufacturing the mineral wool that includes selection of post-consumer or post-industrial recyclable materials. Application of the mineral wool to products such as an acoustical ceiling panel is also provided. | 2011-10-13 |
20110251044 | GLASS SUBSTRATE AND ITS PRODUCTION PROCESS - To provide a glass substrate which has a high glass transition temperature, which has a thermal expansion coefficient close to that of soda lime glass, which has a low specific gravity, which will hardly undergo yellowing, and which further has good melting characters and is thereby produced with high productivity. | 2011-10-13 |
20110251045 | BINDER FOR MONOLITHIC REFRACTORIES AND MONOLITHIC REFRACTORY - The binder for monolithic refractories according to the present invention includes SrAl | 2011-10-13 |
20110251046 | Systems and Methods for Regenerating A Spent Catalyst - Systems and methods for regenerating a spent catalyst are provided. The method can include heating a hydrocarbon and a coke precursor in the presence of catalyst particles to provide a cracked hydrocarbon product and coked catalyst particles. The cracked hydrocarbon product and the coked catalyst particles can be selectively separated to provide a hydrocarbon product and coked catalyst particles. The coked catalyst particles can be mixed with a carrier fluid to provide a mixture. The mixture can be introduced to an upper surface of a dense phase catalyst zone disposed within a regenerator. A gas can be introduced to a lower zone of the dense phase catalyst zone. At least a portion of the carbon deposited on the coked catalyst particles can be combusted to provide a flue gas, heat, and a regenerated catalyst. | 2011-10-13 |
20110251047 | Systems and Methods for Regenerating A Spent Catalyst - Systems and methods for regenerating a spent catalyst are provided. The method can include mixing a spent catalyst with a carrier fluid to provide a mixture. The spent catalyst can include carbon deposited on at least a portion thereof. The carrier fluid can include an oxygen containing gas. The mixture can be introduced to or above an upper surface of a dense phase catalyst zone disposed within a regenerator. A gas can be introduced to a lower zone of the dense phase catalyst zone. At least a portion of the carbon deposited on the catalyst can be combusted to provide a flue gas, heat, and a regenerated catalyst. | 2011-10-13 |
20110251048 | CHABAZITE-TYPE ZEOLITE AND PROCESS FOR PRODUCING THE SAME - A subject for the invention is to provide a chabazite-type zeolite that is expected to have durability and thermal resistance, which are practical properties required of catalyst supports and adsorbent bases, and that has profitability. A chabazite-type zeolite having an SiO | 2011-10-13 |
20110251049 | Method for manufacturing zeolite Y with aluminum and titanium inserted therein - A catalytic composition for hydrotreating of hydrocarbons is made in which a metallic component for hydrogenation is carried on a carrier formed of zeolite Y with aluminum and titanium inserted therein and a porous inorganic oxide. The zeolite Y has: unit cell dimension in a range from 24.25 to 24.60 Å, crystallinity of 95% or more, specific surface area of 500 m | 2011-10-13 |
20110251050 | METHOD AND APPARATUS FOR TESTING A CATALYST MATERIAL - A method of ageing a catalyst material includes at least the steps of: (a) heating a gaseous stream; (b) adding a least one pure hydrocarbon gas and an oxygen-containing gas to the heated gaseous stream to provide a combined stream; and (c) passing the combined stream through the catalyst material. The use of at least one pure hydrocarbon gas and an oxygen-containing gas allows maximum re-circulation of the exit stream from the catalyst material for reuse, while maintaining the correct C, H and O proportions being provided in the combined stream to replicate realistic use of the catalyst material. | 2011-10-13 |
20110251051 | PHOTOCATALYTIC COATING - In one aspect, the present invention is directed to a coating composition. The coating composition comprises photocatalytic particles and an alkali metal silicate binder comprising an alkoxysilane. In another aspect, the present invention is directed to a coated article. The coated article has a photocatalytic coating with improved durability on its external surface that is formed from the aforesaid coating composition. | 2011-10-13 |
20110251052 | CATALYST FOR THE OXIDATION OF SO2 TO SO3 - The invention relates to a catalyst for the oxidation of SO | 2011-10-13 |
20110251053 | SOLVENT-BASED INFILTRATION OF POROUS STRUCTURES - A method for infiltrating a metal salt into a porous structure is described wherein the pores of the porous structure are first flooded with a solvent before contacting the salt mixture to the structure. In one embodiment the metal salt is in molten form when brought into contact with the flooded porous structure. In another embodiment, the metal salt is first brought into contact with the porous structure, and the mixture heated to melt the salt and evaporate the solvent. Thereafter the metal salt can be further reacted to convert it to a desired composition. | 2011-10-13 |
20110251054 | METHOD FOR PREPARING IRON OXIDES - Highly pure iron oxides are prepared by reaction of metallic iron, in the form of microspheroidal particles or of scraps or cuttings, with an agitated aqueous solution of a mono- or polycarboxylic acid with a pKa of 0.5 to 6 relative to the first carboxyl and capable of decomposing, by heating in air at 200 to 350° C., to carbon dioxide and water, using 0.03 to 1.5 moles of acid per g-atoms of iron, a water/iron weight ration of 1 to 20, and by oxidation of the ferrous carboxilate to ferric salt, with an agent selected from oxygen, mixtures containing oxygen, hydrogen peroxide, organic peroxides and hydroperoxides. | 2011-10-13 |
20110251055 | Supported Precious Metal Catalysts Via Hydrothermal Deposition - A process for making a catalyst having precious metal nanoparticles deposited on a support includes first providing an aqueous dispersion of support particles. A pre-treatment slurry is prepared by mixing the aqueous dispersion of support particles with a water-soluble precious metal precursor and a reducing agent. The pre-treatment slurry is hydrothermally treated at a temperature in the range of from about 40° C. to about 220° C. for a time sufficient to deposit precious metal nanoparticles on the surface of the support particles, the precious metal nanoparticles having an average particle size less about 50 nm. | 2011-10-13 |
20110251056 | Method of Fabricating Layered Nano-Carbonate Used for Medium-High Temperature CO2 Sorbent - A technique of fabricating a medium-high temperature CO | 2011-10-13 |
20110251057 | SILICA PARTICLE MANUFACTURING PROCESS - Methods of forming a silica-based products are disclosed. One method comprises: (a) providing a silica containing precursor (SCP) contained in solution that has a pH less than or equal to a pH of 7; (b) optionally doping the SCP with one or more metal species, wherein said doping occurs when the solution has a pH less than or equal to a pH of 7; (c) adjusting the pH of the solution to greater than 7; (d) adding an effective amount of salt to the solution so that the conductivity of the solution is greater than or equal to 4 mS, wherein said addition occurs prior to, simultaneous with, or after the pH adjustment in step 1c; (e) optionally filtering and drying the SCP; and (f) optionally reacting the dried product from step e with a functional group and optionally wherein the resultant functionalized dried product is at least one of the following: a functionalized metal oxide-doped or metal sulfide-doped silica product. Another method comprises: (a) providing a silica containing precursor (SCP) contained in solution that has a pH greater than 7; (b) adjusting the pH of the solution to less than or equal to 7; (c) optionally doping the SCP with one or more metal species, wherein said doping occurs when the solution has a pH less than or equal to a pH of 7; (d) adjusting the pH of the solution to greater than 7; (e) adding an effective amount of salt to the solution so that the conductivity of the solution is greater than or equal to 4 mS, wherein said addition occurs prior to, simultaneous with, or after the pH adjustment in step 2d; (f) optionally filtering and drying the SCP; and (g) optionally reacting the dried product from step f with a functional group and optionally wherein the resultant functionalized dried product is at least one of the following: a functionalized metal oxide-doped or metal sulfide-doped silica product. | 2011-10-13 |
20110251058 | SULFUR CONTAINING SILICA PARTICLE - A silica containing composition is disclosed. The composition comprises a compound having the following formula: (SiO | 2011-10-13 |
20110251059 | PHOTOCHEMICAL MODIFICATION OF SOLID MATERIALS - The present invention relates to a process for modifying or functionalizing oxide surfaces, such as surfaces of SiO | 2011-10-13 |
20110251060 | Thermographic Imaging Element - A thermographic substrate assembly comprised of a colorant and a flexible substrate. This assembly also contains a thermosensitive layer, and the thermosensitive layer contains a binder, a multiplicity of hollow sphere organic pigments, and a thermal solvent. | 2011-10-13 |
20110251061 | Agrochemical Formulations Containing Pyrrolidone Alkylene Oxides - The present invention relates to a composition comprising pesticide and polyalkylene oxide. The invention furthermore relates to pyrrolidone alkylene oxides and the use thereof in agrochemical formulations. It furthermore relates to the use of the composition according to the invention for controlling phytopathogenic fungi and/or undesired vegetation and/or undesired attack by insects or mites and/or for regulating the growth of plants. Furthermore, it relates to the use of a composition according to the invention for controlling undesired attack by insects or mites on plants and/or for controlling phytopathogenic fungi and/or for controlling undesired vegetation, where seeds of useful plants are treated with the composition. Finally, the present invention also relates to seed treated with the composition according to the invention. The present invention comprises combinations of preferred features together with other preferred features. | 2011-10-13 |
20110251062 | Active compound combinations - The invention relates to active compound combinations, in particular within a fungicide composition, which comprises (A) a compound of formula (I) and at least one further respiratory chain complex in inhibitor (B). Moreover, the invention relates to a method for curatively or preventively controlling the phytopathogenic fungi of plants or crops, to the use of a combination according to the invention for the treatment of seed, to a method for protecting a seed and not at least to the treated seed. | 2011-10-13 |
20110251063 | HETEROCYCLIC DIKETONE DERIVATIVES WITH HERBICIDAL ACTION - Heterocyclic compounds of the formula I | 2011-10-13 |
20110251064 | AQUEOUS FLOWABLE CONCENTRATE COMPOSITIONS OF A MICROENCAPSULATED DINITROANILINE HERBICIDE - The present invention relates to aqueous flowable concentrate compositions of a microencapsulated dinitroanline herbicide, in particular pendimethalin, which are flowable and have improved storage stability. The compositions contain: i. 50 to 400 g/l of a dinitroaniline herbicide in the form of microcapsules comprising a core material containing the dinitroaniline herbicide, in particular pendimethalin, and a polymeric wall material, the microcapsules being dispersed in an aqueous phase; ii. 100 to 500 g/l of a glyphosate salt which is dissolved in the aqueous phase and iii. at least one anionic surface-active substance. | 2011-10-13 |
20110251065 | SOLID HERBICIDAL COMPOSITION - A solid herbicidal composition, comprising (1) 1-(4,6-dimethoxypyrimidin-2-yl)-3-(3-trifluoromethyl-2-pyridylsulfonyl)urea or a salt thereof, (2) at least one member selected from the group consisting of N-(phosphonomethyl)glycine, 4-[hydroxy(methyl)phosphinoyl-homoalanine, 4-[hydroxy(methyl)phosphinoyl]-homoalanylalanylalanine and salts thereof, (3) a surfactant, and (4) a stabilizer. | 2011-10-13 |
20110251066 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS - The present invention relates to isoxazole compounds of formula (I) having plant growth regulating properties, to agricultural compositions comprising them, and to the use of said compounds for regulating plant growth. | 2011-10-13 |
20110251067 | Hydrolysis Resistant Organomodified Trisiloxane Surfactants - Three types of trisiloxane surfactants having the basic formula: | 2011-10-13 |
20110251068 | PARASITIC PLANT CONTROL AGENT AND PARASITIC PLANT CONTROL METHOD - Disclosed is a parasitic plant control agent which can control a parasitic plant effectively. Also disclosed is a parasitic plant control method. A parasitic plant can be controlled by inhibiting the metabolism of gentianose in the parasitic plant to inhibit the germination of the parasitic plant. | 2011-10-13 |
20110251069 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS - The present invention relates to thiophene, furan and pyrrole compounds of formula (I) having plant growth regulating properties, to agricultural compositions comprising them, and to the use of said compounds for regulating plant growth. | 2011-10-13 |
20110251070 | Agrochemical Oil Compositions Comprising Alkylpolysiloxane Adjuvants of High Silicone Character - The invention relates to agrochemical compositions comprising oils and alkylpolysiloxanes of high silicone character (HSCAS) with good oil compatibility which improve the spreading behavior and reduce surface tension of oil-based agricultural formulations, and optionally comprising agrochemically active ingredients such as fungicides, insecticides or herbicides and/or inert ingredients such as emulsifiers and other agrochemically acceptable components. | 2011-10-13 |
20110251071 | Method of Realization of Hyperconductivity and Super Thermal Conductivity - The application relates to electricity, electro-physics and thermo conductivity of materials, to the phenomena of zero electric resistance, i.e. to hyperconductivity (superconductivity) and zero thermal resistance, i.e. to superthermoconductivity of materials at near-room and higher temperatures. The matter: on the surface of in the volume of non-degenerate or poorly degenerate semiconductor material or layer of such material on semi-insulating or dielectric substrate the electrodes are located forming rectifying contacts to the material. The distance between the electrodes (D) is chosen much smaller comparing to the depth of penetration into the material of the electric field caused by their contact difference of potentials (L), (D<2011-10-13 | |
20110251072 | ASSEMBLY OF QUASICRYSTALLINE PHOTONIC HETEROSTRUCTURES - A method and system for assembling a quasicrystalline heterostructure. A plurality of particles is provided with desirable predetermined character. The particles are suspended in a medium, and holographic optical traps are used to position the particles in a way to achieve an arrangement which provides a desired property. | 2011-10-13 |
20110251073 | Compositions And Methods Comprising Variant Microbial Proteases - The present invention provides methods for protein engineering. Specifically, the invention provides methods utilizing site evaluation libraries to design libraries that optimize two or more properties of a protein. The present invention also provides variant subtilisins suitable for various uses. | 2011-10-13 |
20110251074 | METHOD FOR IDENTIFYING HLA COMPLEXES ASSOCIATED WITH ADVERSE DRUG REACTIONS - A method for identifying from an HLA library an HLA complex that specifically binds to a compound. This method can be relied on to assess whether a compound is likely to induce an adverse drug reaction and, if so, in which human population. | 2011-10-13 |
20110251075 | SYSTEM AND METHOD FOR THE ANALYSIS OF BODILY FLUIDS - A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into which a plurality of cavities may be formed. A series of chemically sensitive particles are, in one embodiment positioned within the cavities. The particles may be configured to produce a signal when a receptor coupled to the particle interacts with the analyte. Using pattern recognition techniques, the analytes within a multi-analyte fluid may be characterized. | 2011-10-13 |
20110251076 | NON-INVASIVE DETECTION OF FETAL GENETIC TRAITS - Blood plasma of pregnant women contains fetal and (generally >90%) maternal circulatory extracellular DNA. Most of said fetal DNA contains ≦500 base pairs, said maternal DNA having a greater size. Separation of circulatory extracellular DNA of <500 base pairs results in separation of fetal from maternal DNA. A fraction of a blood plasma or serum sample of a pregnant woman containing, due to size separation (e.g. by chromatography, density gradient centrifugation or nanotechnological methods), extracellular DNA substantially comprising ≦500 base pairs is useful for non-invasive detection of fetal genetic traits (including the fetal RhD gene in pregnancies at risk for HDN; fetal Y chromosome-specific sequences in pregnancies at risk for X chromosome-linked disorders; chromosomal aberrations; hereditary Mendelian genetic disorders and corresponding genetic markers; and traits decisive for paternity determination) by e.g. PCR, ligand chain reaction or probe hybridization techniques, or nucleic acid arrays. | 2011-10-13 |
20110251077 | Methods and Systems for Diagnosis of Non-Central Nervous System (CNS) Diseases in CNS Samples - The invention features methods, systems, and compositions for diagnosing non-central nervous system (non-CNS) disorders by detecting changes in gene expression in the CNS, e.g., in cerebrospinal fluid, in brain or spinal cord tissue samples, or other bodily fluid samples. | 2011-10-13 |
20110251078 | Methods for Sequencing Individual Nucleic Acids Under Tension - The invention provides apparatuses and methods of use thereof for sequencing nucleic acids subjected to a force, and thus considered under tension. The methods may employ but are not dependent upon incorporation of extrinsically detectably labeled nucleotides. | 2011-10-13 |
20110251079 | HIGH THROUGHPUT NUCLEIC ACID SEQUENCING BY EXPANSION - Nucleic acid sequencing methods and related products are disclosed. Methods for sequencing a target nucleic acid comprise providing a daughter strand produced by a template-directed synthesis, the daughter strand comprising a plurality of subunits coupled in a sequence corresponding to a contiguous nucleotide sequence of all or a portion of the target nucleic acid, wherein the individual subunits comprise a tether, at least one probe or nucleobase residue, and at least one selectively cleavable bond. The selectively cleavable bond(s) is/are cleaved to yield an Xpandomer of a length longer than the plurality of the subunits of the daughter strand, the Xpandomer comprising the tethers and reporter elements for parsing genetic information in a sequence corresponding to the contiguous nucleotide sequence of all or a portion of the target nucleic acid. Reporter elements of the Xpandomer are then detected. Corresponding products, including Xpandomers and oligomeric and monomeric substrate constructs are also disclosed. | 2011-10-13 |
20110251080 | SAMPLE PROCESSING APPARATUS AND METHOD - The invention relates to a sample processing apparatus comprising a holder for a microtiter plate comprising a plurality of microwells, optical measurement unit for measuring optical responses of samples dosed to the microwells, and a computing unit configured to analyze the optical responses in order to detect dosing failures in said plurality of microwells, and if a dosing failure has been detected in one or more of the microwells, to communicate the existence of the dosing failure to a user of the apparatus through signaling means or to store data indicative of the dosing failure to data storage means for further use. In particular, the invention relates to detecting dosing failures in before, during and after a PCR process. | 2011-10-13 |
20110251081 | METHODS AND COMPOSITIONS FOR DETERMINING GENE FUNCTION - The invention relates to methods and systems (e.g., computer systems and computer program products) for characterizing cellular constituents, particularly genes and gene products. In particular, the invention provides methods for assigning or determining the biological function of uncharacterized genes and gene products by using “response profiles,” i.e., measurements of pluralities of cellular constituents in cells having a modified gene or gene product, as phenotypic markers for the gene or gene product. Methods are provided for clustering such response profiles so that similar or correlated response profiles are organized into the same cluster. The invention also provides databases or “compendiums” of response profiles to which the response profile of an uncharacterized gene or gene product can compared. | 2011-10-13 |
20110251082 | BIOMARKERS FOR BREAST CANCER - The present invention uses 2-dimensional differential gel electrophoresisgel (2D-DIGE) and mass spetrum techniques to identify breast cancer biomarkers in transformed breast cells. In summary, the present invention identifies numerous putative breast cancer markers from various stages of breast cancer. The results of the invention aids in developing proteins identified as useful diagnostic and therapeutic candidates on breast cancer research. | 2011-10-13 |
20110251083 | Multiplexed Amplification of Short Nucleic Acids - The present teachings provide methods, compositions, and kits for reverse transcribing and amplifying small nucleic acids such as micro RNAs. High levels of multiplexing are provided by the use of a zip-coded stem-loop reverse transcription primer, along with a PCR-based pre-amplification reaction that comprises a zip-coded forward primer. Detector probes in downstream decoding PCRs can take advantage of the zip-code introduced by the stem-loop reverse transcription primer. In some embodiments, further amplification is achieved by cycling the reverse transcription reaction. The present teachings also provide compositions and kits useful for performing the reverse transcription and amplification reactions described herein. | 2011-10-13 |
20110251084 | System for the Detection of a Biological Pathogen and Use Thereof - The invention features compositions and methods that are useful for the detection of a target analyte, such as a pathogen, in a sample. | 2011-10-13 |
20110251085 | IN VITRO METHOD TO DETERMINE WHETHER A DRUG CANDIDATE ACTIVE AGAINST A TARGET PROTEIN IS ACTIVE AGAINST A VARIANT OF SAID PROTEIN - The present invention relates to the field of virology. More precisely, the invention provides a method of determining the ability of a test compound to modulate the biological activity of a variant of a target protein, wherein said test compound is previously known to modulate the biological activity of said protein. This invention is useful to determine whether a drug candidate, such as anti-viral compounds (eg. against hepatitis C virus: NS5B, NS3), active against a target protein is active against a variant of said protein (eg. polymorphisms, genotypes or mutants). | 2011-10-13 |
20110251086 | NEUROBLASTOMA PROGNOSTIC MULTIGENE EXPRESSION SIGNATURE - The current invention relates to new tools and methods enabling neuroblastoma patient stratification into prognostic favorable or unfavorable groups. The invention is based on the re-analysis of published gene expression data-sets studying neuroblastoma tumors generating different prognostic gene lists. The overlapping gene lists were subsequently tested for their prognostic power on both the published tumor samples and on an unseen large set of unpublished samples, greatly increasing the statistical power of prognostic analyses. In addition, expression analysis of miRNAs in neuroblastoma tumors with different prognosis was performed. By doing this, the inventors could establish a neuroblastoma prognostic classifier with highly improved prognostic power, which is independent from the tumor sample set used to establish it. This classifier and its related prognostic tools and methods are thus perfectly suitable for routine clinical assessment of neuroblastoma prognosis. | 2011-10-13 |
20110251087 | PROGNOSTIC AND DIAGNOSTIC METHOD FOR CANCER THERAPY - The present invention relates to methods for the diagnosis and prognosis of aggressive forms of cancer using a combination of gene expression signatures. | 2011-10-13 |
20110251088 | LARIAT APTAMER: APTAMER CANDIDATE EXCLUSION BY NUCLEASE DIGESTION - A method for identifying aptamers that bind to target molecules may include contacting an oligonucleotide library with target molecule and digesting unbound oligonucleotides with one or more endonucleases, one or more exonucleases, or one or more endonucleases in combination with one or more exonucleases. The unbound oligonucletides lend themselves to nuclease digestion because their flanking sequences are complementary and form predictable, terminal, secondary structure (a Lariat Aptamer). Bound molecules (aptamers) are protected from nuclease digestion and become enriched. A method for identifying aptamers may further include optionally subjecting selected aptamers to one or more rounds of selection under conditions of increased stringency. A method for identifying aptamers may include yet further amplifying selected aptamers. The described methods may be performed in a screen for identifying aptamers either alone or in combination with other methods typically employed in the art for selecting aptamers (such as, e.g., SELEX). Also contemplated herein are systems and kits for accomplishing the above. | 2011-10-13 |
20110251089 | METHODS FOR SYNTHESIS OF ENCODED LIBRARIES - The present invention provides a method of synthesizing libraries of molecules which include an encoding oligonucleotide tag. | 2011-10-13 |
20110251090 | PANCREATIC CANCER RELATED GENE TTLL4 - The present invention relates to the roles played by TTLL4 genes in pancreatic cancer carcinogenesis and features a method for treating or preventing pancreatic cancer by administering a double-stranded molecule against one or more of the TTLL4 genes or a composition, vector or cell containing such a double stranded molecule. Also, disclosed are methods of identifying compounds for treating and preventing pancreatic cancer, using as an index their effect on the over-expression of TTLL4 in the pancreatic cancer cell. | 2011-10-13 |
20110251091 | THYROID TUMORS IDENTIFIED - The invention relates to methods and kits for detecting thyroid cancer by detecting differences in the expression of genes that are differentially expressed in thyroid cancer cells. | 2011-10-13 |
20110251092 | Use of Photopolymerization for Amplification and Detection of a Molecular Recognition Event - The invention provides methods to detect molecular recognition events. The invention also provides methods to detect the presence of or identify a target species based on its interaction with one or more probe species. The methods of the invention are based on amplification of the signal due to each molecular recognition event. The amplification is achieved through photopolymerization, with the polymer formed being associated with the molecular recognition event. In one aspect, a fluorescent polymer, a magnetic polymer, a radioactive polymer or an electrically conducting polymer can form the basis of detection and amplification. In another aspect, a polymer gel swollen with a fluorescent solution, a magnetic solution, a radioactive solution or an electrically conducting solution can form the basis of detection and amplification. In another aspect, detectable particles can be included in the polymer formed. In another aspect, sufficient polymer forms to be detectable by visual inspection. | 2011-10-13 |
20110251093 | ANALYSIS, SECURE ACCESS TO, AND TRANSMISSION OF ARRAY IMAGES - Systems and methods are provided the autocentering, autofocusing, acquiring, decoding, aligning, analyzing and exchanging among various parties, images, where the images are of arrays of signals associated with ligand-receptor interactions, and more particularly, ligand-receptor interactions where a multitude of receptors are associated with microparticles or microbeads. The beads are encoded to indicate the identity of the receptor attached, and therefore, an assay image and a decoding image are aligned to effect the decoding. The images or data extracted from such images can be exchanged between de-centralized assay locations and a centralized location where the data are analyzed to indicate assay results. Access to data can be restricted to authorized parties in possession of certain coding information, so as to preserve confidentiality. | 2011-10-13 |
20110251094 | BIOMARKERS FOR HYPERTENSIVE DISORDERS OF PREGNANCY - The application discloses new biomarkers for hypertensive disorders of pregnancy and particularly preeclampsia; methods for the diagnosis, prediction, prognosis and/or monitoring said disorders based on measuring said biomarkers; and kits and devices for measuring said biomarker and/or performing said methods. | 2011-10-13 |
20110251095 | MARA FAMILY HELIX-TURN-HELIX DOMAINS AND THEIR METHODS OF USE - An important advance in the battle against drug resistance by elucidating the domains of MarA which are critical in mediating its function. Accordingly, MarA family protein helix-turn-helix domains, mutant MarA family protein helix-turn-helix domains and methods of their use, for example, in screening assays to identify compounds which are useful as antiinfective agents and in screening assays to identify loci which are involved in mediating antibiotic resistance are described. | 2011-10-13 |
20110251096 | Health Test for a Broad Spectrum of Health Problems - Provided herein are methods and devices for the detection of conditions or disorders by detecting altered levels of stress response pathway biomarkers. Also provided are methods and reagents for identifying panels of biomarkers associated with a condition or disorder. | 2011-10-13 |
20110251097 | DIAGNOSTIC KIT OF COLON CANCER USING COLON CANCER RELATED MARKER AND DIAGNOSTIC METHOD THEREOF - The present invention relates to a composition for diagnosing colon cancer. The composition comprises at least one marker for measuring an mRNA or protein expression level of at least one gene specific for colon cancer. It can screen the genes which are overexpressed specifically only in colon cancer tissues or blood. The present invention can quantitatively analyze both the mRNA expression levels of the genes and the expression levels of the proteins encoded by the gene at the same time, thereby diagnosing colon caner of an early stage with a high level of reliability. | 2011-10-13 |
20110251098 | Biomarkers in Peripheral Blood Mononuclear Cells for Diagnosing or Detecting Lung Cancers - Methods and compositions are provided for diagnosing or detecting a condition, e.g., lung disease in a mammalian subject by use of a micro-RNA expression level or an expression level profile of multiple miRNA in the peripheral blood mononuclear cells (PBMC) of the subject which is characteristic of COPD or NSCLC. Detection of changes in expression in specific miRNA biomarkers from that of a reference sample or miRNA expression profile are correlated with non-small cell lung cancer (NSCLC) and/or COPD and permit differentiation among healthy subjects, subjects with COPD and subjects with adenocarcinoma or squamous cell carcinoma. | 2011-10-13 |
20110251099 | SERUM MARKERS PREDICTING CLINICAL RESPONSE TO ANTI-TNFa ANTIBODIES IN PATIENTS WITH ANKYLOSING SPONDYLITIS - The invention provides tools for management of patients diagnosed with ankylosing spondylitis and prior to the initiation of therapy with an anti-TNFalpha agent. The tools are specific markers and algorithms of predicting response to therapy based on standard clinical primary and secondary end-points using serum marker concentrations. In one embodiment the baseline level of leptin or osteocalcin is used to predict the response at Week 14 after the initiation of therapy. In another embodiment, the change in a serum protein biomarker after 4 weeks of therapy is used such as complement component 3. | 2011-10-13 |
20110251100 | COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING INFLAMMATORY BOWEL DISEASE AND RELATED DISORDERS - The present invention features biomarkers capable of diagnosing inflammatory bowel disease and methods of using such biomarkers to diagnose and selecting treatments for inflammatory bowel diseases. | 2011-10-13 |
20110251101 | COMBINATORIAL DECODING OF RANDOM NUCLEIC ACID ARRAYS - Methods disclosed herein relate to identification of nucleotides in a nucleotide sequence. | 2011-10-13 |
20110251102 | HIGH THROUGHPUT SCREENING OF ION CHANNELS - Multi-well plates having contoured well designs allow multi-stage high throughput parallel assaying of ion channels or ion transporters. A well of a multi-well plate has a bottom region that is sized and shaped to simultaneous accommodate a sensing electrode and a pipette for delivering, e.g., test compounds, wash fluid, and optionally ligands. Such multi-well plates may be coupled with an instrument having a pipette head and an electrode plate. Such arrangement facilitates fluidic contact between cells and fluids provided via a pipette. It also facilitates washing of wells with buffers or other wash solutions to allow serial exposure of test cells to various reagents or other stimuli. Generally, the design allows control and test experiments to be performed on the same cell (or cells) in a single well. | 2011-10-13 |
20110251103 | TARGETED CHEMICAL HIGH-THROUGHPUT SCREENING METHOD - A novel method which integrates a “sensitized” chemical genetic high-throughput screen (HTS) with RNA interference (RNAi) screening technology is described herein. The present inventors used this method to identify specific small molecule inhibitors and activators of the Wnt pathway. More particularly, the screening method of the present invention may be used to identify small molecule inhibitors and activators that specifically target the activity of a stabilized pool of β-catenin. A number of compounds identified using the instant method, are shown herein to be small molecule inhibitors of the Wnt pathway that specifically target the activity of the stabilized pool of β-cat. The inhibitors identified by the present method may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, cancer, and others. | 2011-10-13 |
20110251104 | COMPOSITIONS AND METHODS FOR DETECTING DEACETYLASE ACTIVITY - A method for the quantitative determination of the activity of enzymes in the Sirtuin family through the quantification of the acetyl-ADPr product that is formed is provided. The method described allows for a wide range of substrates, including peptides, intact proteins, or protein complexes (e.g. nucleosomes) to be used as substrates without the need for additional analytical methods to be developed. | 2011-10-13 |
20110251105 | METHODS FOR DETECTING TARGET ANALYTES AND ENZYMATIC REACTIONS - A microsphere-based analytic chemistry system and method for making the same is disclosed in which microspheres or particles carrying bioactive agents may be combined randomly or in ordered fashion and dispersed on a substrate to form an array while maintaining the ability to identify the location of bioactive agents and particles within the array using an optically interrogatable, optical signature encoding scheme. A wide variety of modified substrates may be employed which provide either discrete or non-discrete sites for accommodating the microspheres in either random or patterned distributions. The substrates may be constructed from a variety of materials to form either two-dimensional or three-dimensional configurations. In a preferred embodiment, a modified fiber optic bundle or array is employed as a substrate to produce a high density array. The disclosed system and method have utility for detecting target analytes and screening large libraries of bioactive agents. | 2011-10-13 |
20110251106 | PVII PHAGE DISPLAY - The present invention provides an alternative scaffold for peptides displayed on filamentous phages through novel fusion proteins primarily originating from pVII. Libraries of filamentous phages can be created from fusion proteins, and a phage display system comprising a phagemid and a helper phage is a part of the invention. An aspect of the invention is a kit containing a phage display system comprising a phagemid and a helper phage that contains a nucleic acid encoding the fusion protein of the invention. | 2011-10-13 |
20110251107 | G-QUADRUPLEX BINDING ASSAYS AND COMPOUNDS THEREFOR - The present invention provides methods for assaying binding of compounds to G-quadruplex structures. Also provided are methods for screening candidate compounds for use as modulators of G-quadruplex activity, and methods for screening candidate compounds for telomerase inhibitory activity. The invention further provides novel compounds useful in the assays of the invention. | 2011-10-13 |
20110251108 | METHODS AND MATERIALS RELATING TO STEM CELL GROWTH FACTOR-LIKE POLYPEPTIDES AND POLYNUCLEOTIDES - The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted stem cell growth factor-like polypeptides. Other aspects of the invention include vectors containing processes for producing novel human secreted stem cell growth factor-like polypeptides, and antibodies specific for such polypeptides. | 2011-10-13 |
20110251109 | Fluidic methods for devices for parallel chemical reactions - Fluidic methods and devices for conducting parallel chemical reactions are disclosed. The methods are based on the use of in situ photogenerated reagents such as photogenerated acids, photogenerated bases, or any other suitable chemical compounds that produce active reagents upon light radiation. The present invention describes devices and methods for performing a large number of parallel chemical reactions without the use of a large number of valves, pumps, and other complicated fluidic components. The present invention provides microfluidic devices that contain a plurality of microscopic vessels for carrying out discrete chemical reactions. Other applications may include the preparation of microarrays of DNA and RNA oligonucleotides, peptides, oligosaccharides, phospholipids and other biopolymers on a substrate surface for assessing gene sequence information, screening for biological and chemical activities, identifying intermolecular complex formations, and determining structural features of molecular complexes. | 2011-10-13 |
20110251110 | Methods for Sequencing Individual Nucleic Acids Under Tension - The invention provides apparatuses and methods of use thereof for sequencing nucleic acids subjected to a force, and thus considered under tension. The methods may employ but are not dependent upon incorporation of extrinsically detectably labeled nucleotides. | 2011-10-13 |
20110251111 | FOAMING AGENT FOR SUBTERRANEAN FORMATIONS TREATMENT, AND METHODS OF USE THEREOF - A wellbore treatment fluid is formed from an aqueous medium, a gas component, a viscosifying agent, and a surfactant. The surfactant is represented by the chemical formula: | 2011-10-13 |
20110251112 | Graft Polymer and Related Methods and Compositions - The present invention relates to a graft polymer of (a) a polyalphaolefin having a weight average molecular weight of less than 15000 and a polydispersity of 1.1 to 10; (b) a nitrogenous, ethylenically unsaturated, aliphatic or aromatic, graftable monomer having from 2 to about 50 carbon atoms; and (c) an organo-metallic compound selected from organo-molybdenum, organo-titanium, organo-manganese compounds and mixtures thereof; a process for making the graft polymer; and a lubricating oil composition comprising a major amount of a base oil and a minor amount of the graft polymer. | 2011-10-13 |
20110251113 | LUBRICATING GREASE COMPOSITIONS - A Lubricating grease composition comprising a base oil and a thickener system comprising (a) a lithium soap of a C | 2011-10-13 |
20110251114 | METHOD FOR PRODUCING MANNICH ADDUCTS THAT CONTAIN POLYISOBUTYLENE PHENOL - Polyisobutenylphenol-containing Mannich adducts are prepared by
| 2011-10-13 |
20110251115 | HYDROPHOBIC GROUP-CONTAINING COPOLYMER AND PROCESS FOR THE PRODUCTION THEREOF - [Objective] This invention is to provide a novel copolymer suitably applicable to a detergent composition having an excellent precipitation inhibitory ability and showing a good washing effect even under severe conditions of washing with water used to take Japanese bath. | 2011-10-13 |
20110251116 | MULTIPLE MUTATION VARIANTS OF SERINE PROTEASE - The present invention provides novel | 2011-10-13 |
20110251117 | ALPHA-AMYLASE MUTANTS - The present invention relates to a method of constructing a variant of a parent Termamyl-like alpha-amylase, which variant has alpha-amylase activity and at least one altered property as compared to the parent alpha-amylase, comprises
| 2011-10-13 |
20110251118 | ADSORPTION AGENT FOR SEPARATING DYED COMPOUNDS FROM AQUEOUS FORMULATIONS - In order to separate dyes from aqueous solutions, an improved adsorption agent is proposed, which can be produced according to a method, wherein in a first reaction step, a multifunctional alcohol is reacted with an alkylene oxide into a star-shaped OH-terminated polyether. In a second reaction step, the polyether is reacted with a silane compound such that at an average more than one alkoxy silane group per molecule polyether is present, and in a third reaction step a cross-linking product is obtained by condensation in the presence of acids, wherein optionally further siloxane group-containing modifying agents can be incorporated, and wherein in a final treatment step, the cross-linked products obtained in said manner are separated and optionally dried or ground, | 2011-10-13 |
20110251119 | MIXTURES OF ITACONIC ACID OR ITACONIC ACID DERIVATIVES AND PRIMARY AMINES FOR PRODUCING 1,3- AND 1,4-ALKYL METHYL PYRROLIDONES - The present invention relates to a mixture comprising itaconic acid or an itaconic acid derivative and a primary amine of the formula (I) | 2011-10-13 |
20110251120 | Antimicrobial Peptides and Methods of Identifying the Same - Antimicrobial peptides and methods of identifying the same are provided. | 2011-10-13 |
20110251121 | USE OF CYSTEINE-RICH WHEY DERIVED PROTEIN IN PATIENTS RECEIVING CHEMOTHERAPY AND/OR RADIOTHERAPY TO IMPROVE PATIENT SURVIVAL - A cysteine-rich undenatured whey-derived protein formulation did not interfere with the tumor-cytotoxic effects of chemotherapy and radiation therapy and did not have a negative effect on the clinical outcome, that is, negatively affect survival and increase mortality. Indeed, use of a high-cysteine undenatured whey derived protein in the treatment of cancer patients resulted in an increase in patient survival. | 2011-10-13 |
20110251122 | POLYNUCLEOTIDE CONSTRUCTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TARGETED DOWNREGULATION OF ANGIOGENESIS AND ANTICANCER THERAPY - A novel nucleic acid construct for down-regulating angiogenesis in a tissue of a subject is provided. The nucleic acid construct includes: (a) a first polynucleotide region encoding a chimeric polypeptide including a ligand binding domain fused to an effector domain of an apoptosis signaling molecule; and (b) a second polynucleotide region encoding a cis acting regulatory element being for directing expression of the chimeric polypeptide in a specific tissue or cell; wherein the ligand binding domain is selected such that it is capable of binding a ligand present in the specific tissue or cell, whereas binding of the ligand to the ligand binding domain activates the effector domain of the apoptosis signaling molecule. Also provided are methods of utilizing this nucleic acid construct for treating diseases characterized by excessive or aberrant neo-vascularization or cell growth. | 2011-10-13 |
20110251123 | ORAL PHARMACEUTICAL COMPOSITION OF DESMOPRESSIN - The present invention relates to a liquid oral pharmaceutical composition of desmopressin, and its use for the treatment of central diabetes insipidus, primary nocturnal enuresis, bleeding in patients with Hemophilia A, with von Willebrand-Jürgens disease and postoperative bleeding. | 2011-10-13 |
20110251124 | REGULATION OF MINERAL AND SKELETAL METABOLISM - A method is disclosed whereby levels of calcium, phosphate and parathyroid hormone are measured in a patient. The patient is treated with a formulation comprising a compound having phosphotonin activity and thereafter measurements are made again. Dosing of the formulation is adjusted based on measurements with measuring, administering and adjusting dosing continually repeated as needed. | 2011-10-13 |
20110251125 | DISODIUM SALTS, MONOHYDRATES, AND ETHANOL SOLVATES FOR DELIVERING ACTIVE AGENTS - The inventors have discovered that the disodium salt of certain delivery agents has surprisingly greater efficacy for delivering active agents than the corresponding monosodium salt. Furthermore, the inventors have discovered that the disodium salts of these delivery agents form solvates with ethanol and hydrates with water. The delivery agents have the formula | 2011-10-13 |
20110251126 | INTESTINAL TREATMENT - Y4 receptor agonists which are selective for the Y4 receptor over the Y1 and Y2 receptors, are useful in the prevention and/or treatment of damage to bowel function caused by radiation therapy, radiation exposure, cytotoxic chemotherapy, inflammation, or ischemia-reperfusion of intestinal mucosa. | 2011-10-13 |