| 41st week of 2008 patent applcation highlights part 37 |
| Patent application number | Title | Published |
|---|
| 20080248402 | PHOTOSENSITIVE COMPOSITION FOR VOLUME HOLOGRAM RECORDING AND PHOTOSENSITIVE MEDIUM FOR VOLUME HOLOGRAM RECORDING - A photosensitive composition and A photosensitive medium for volume hologram recording comprises a photopolymerization reactive compound (a monomer) and any one of the following binder: (a) an organic-inorganic hybrid polymer obtainable by copolymerizing an organometallic compound of the formula 1 “R | 2008-10-09 |
| 20080248403 | METHOD AND SYSTEM FOR IMPROVING CRITICAL DIMENSION UNIFORMITY - A method for improving critical dimension uniformity of a wafer includes exposing a plurality of mask patterns on a first plurality of substrates at predetermined locations with common splits conditions of focus and exposure dose for each of the first plurality of substrates to form a plurality of perturbed wafers; measuring a critical dimension of the plurality of mask patterns at each of the predetermined locations for each of the plurality of perturbed wafers; averaging the critical dimension measured at each of the predetermined locations over the plurality of perturbed wafers to form a perturbed critical dimension map; measuring a sidewall angle of the plurality of mask patterns; averaging the sidewall angle measured to form a perturbed sidewall angle map; and providing the perturbed critical dimension map and the perturbed sidewall angle map to an exposure tool. | 2008-10-09 |
| 20080248404 | Method for Controlling Phase Angle of a Mask by Post-Treatment - A method for controlling phase angle of a mask is provided. A mask comprising a substrate and an absorber is formed. A nitrogen-containing plasma treatment is performed on the mask to reduce the phase angle. Alternatively, a nitrogen-containing plasma treatment is performed on the mask, followed by a vacuum ultraviolet treatment to form a passivated layer on the mask. | 2008-10-09 |
| 20080248405 | LIQUID TONER-BASED PATTERN MASK METHOD AND SYSTEM - A liquid toner-based pattern mask system and methods of masking and patterning a substrate employ a polymer-based liquid toner as a pattern mask. The liquid toner is deposited on the substrate in a masking pattern. The pattern mask is lifted off of the substrate after patterning the substrate using a lift-off technique that breaks a bond between the surface of the substrate and the pattern mask. | 2008-10-09 |
| 20080248406 | PELLICLE AND METHOD FOR PREPARING THE SAME - The present invention aims at reducing the thickness of a pellicle membrane while providing a strong pellicle membrane. The method for manufacturing a pellicle of the present invention comprises the steps of forming, on a base plate, a pellicle membrane comprising a fluorocarbon resin; peeling the membrane off the base plate; and heating the pellicle membrane. The heating temperature is preferably lower than the glass transition temperature of the pellicle membrane. The pellicle membrane has a tensile strength not smaller than 38.25 MPa (390 kgf/cm | 2008-10-09 |
| 20080248407 | PELLICLE - The invention aims at providing a pellicle that does not impair photomask flatness when the pellicle is bonded to the photomask. In the pellicle of the present invention, the surface at which the pellicle frame is mounted on a photomask has a flatness not exceeding 30 μm, while the surface of the pellicle frame on the pellicle membrane side has a flatness not exceeding 15 μm. | 2008-10-09 |
| 20080248408 | Photomask and Method for Forming a Non-Orthogonal Feature on the Same - A photomask and method for forming a non-orthogonal feature on the photomask are provided. A method for forming a non-orthogonal feature on a photomask blank includes providing a mask layout file including a primitive shape and fracturing the primitive shape to create a plurality of writeable shapes in a mask pattern file. A non-orthogonal feature formed by the writeable shapes is formed on a photomask blank by using a lithography system to image the writeable shapes from the mask pattern file onto a resist layer of the photomask blank. | 2008-10-09 |
| 20080248409 | Reflective Mask Blank, Reflective Mask and Methods of Producing the Mask Blank and the Mask - A reflective mask blank has a substrate ( | 2008-10-09 |
| 20080248410 | METHOD FOR FORMING COLOR FILTER - A method for forming a color filter is provided. A substrate having a passivasion layer thereon is provided. The passivasion layer has at least one trench therein within a peripheral region of the substrate. A first color filter layer is formed over the passivasion layer to fill the trench by performing a first spin-on coating process with a first spin rate. Thereafter, the first color filter layer is patterned so as to form a plurality of first color filter blocks in a display region of the substrate and expose a portion of the passivasion layer. A second color filter layer is formed over the passivasion layer by performing a second spin-on coating process with a second spin rate, which is larger than the first spin rate. Next, the second color filter layer is patterned to form a plurality of second color filter blocks between the first color filter blocks respectively. | 2008-10-09 |
| 20080248411 | Display Medium and Displaying Method - Provided are an indicating material having excellent facility and high security and an indicating method for recording and indicating information on this indicating material. The indicating material has a structure that an ultraviolet light-screening layer having visible light-transmitting ability is laminated on a recording layer having visible light-transmitting ability and composed of a recording layer-forming material containing a color-developing component that becomes a color-developed state by the action of ultraviolet light. The indicating method is an indicating method for recording and indicating information on the above-described indicating material, comprising condensing a laser beam having a wavelength of a visible range or longer on the recording layer in the indicating material to irradiate the recording layer with the laser beam and recording and indicating the information by two-photon absorption. | 2008-10-09 |
| 20080248412 | SUPERVISORY ETCH CD CONTROL - Exemplary embodiments provide a controller system and method to control etch critical dimensions (CDs) during semiconductor manufacturing processes when the etch elements cannot be manipulated to control such end. The controller system includes a photo CD controller and an etch CD controller. The photo CD controller includes a first feedback loop that correlates a measured photo CD of a photo-processed semiconductor product back to the photo-process. The etch CD controller calculates a CD bias from the measured photo CD, a measured etch CD of a further etch-processed semiconductor product, and manufacturing targets for the photo CD and the etch CD. The CD bias is then fed back to the photo CD controller as a device-level CD-offset to adjust the target photo CD, which modifies the photo-process and generates the etch CD on the target etch CD. This automated etch CD control can be used for error corrections for product-to-product variations. | 2008-10-09 |
| 20080248413 | LIQUID DEVELOPING AGENT, METHOD OF PRODUCING THE SAME AND METHOD OF PRODUCING DISPLAY DEVICE - On the surface of a core particle of a toner particle, a silane coupling agent treatment layer, a coating layer of thermoplastic resin microparticles applied to the core particle and a charge control agent added to the coating layer through the silane coupling agent treatment layer are provided, wherein the toner particle has a particle diameter of 1 to 10 μm, or on the surface of a core particle of a toner particle, a coating layer of thermoplastic resin microparticles and a charge control agent added to the coating layer and made of an organic compound containing at least one type of lanthanoid metal are provided, or on a ZnS type fluorescent body core particle, a coating layer of thermoplastic resin microparticles and a charge control agent added to the coating layer and including a metal compound containing the IIA metal or IIIA group metal are provided. | 2008-10-09 |
| 20080248414 | POLYESTERS FOR TONER FOR ELECTROPHOTOGRAPHY - The present invention relates to a polyester having an excellent hydrolysis resistance even when used in a process for producing a toner for electrophotography which includes a step of forming a raw material into particles in an aqueous medium, and a toner for electrophotography which contains the polyester and is excellent in storage stability and fixing property. There are provided a polyester for a toner for electrophotography which is used in a process for producing a toner including a step of forming a raw material component into particles in an aqueous medium or a solution, and produced by polycondensing an alcohol component with a carboxylic acid component containing at least one compound selected from the group consisting of an alkyl succinic acid and an alkenyl succinic acid, as well as a toner for electrophotography which contains the polyester. | 2008-10-09 |
| 20080248415 | METHOD OF MANUFACTURING AGGREGATE PARTICLES AND TONER - A method of manufacturing aggregate particles capable of obtaining aggregate particles having high mechanical strength, small particle size, with narrow particle size distribution width by preventing interfusion of bubbles in the aggregate particles during stirring is provided. Aggregate particles are manufactured by stirring a resin particle slurry including resin particles dispersed in an aqueous medium and contained in a stirring vessel by a stirring section having a impeller and two or more screen members disposed so as to surround the impeller in the stirring vessel and each formed with a plurality of slits and aggregating the resin particles. | 2008-10-09 |
| 20080248416 | TONER PREPARATION METHOD AND APPARATUS, AND TONER PREPARED THEREBY - A method of preparing a toner, including periodically dripping and discharging a droplet of a toner constituent liquid including a resin and a colorant; and solidifying and granulating the droplet, wherein the dripper includes a thin film including plural nozzles; and an oscillator including an oscillation generator generating an oscillation; and an oscillation amplifier, including an oscillation surface facing the thin film in parallel therewith, amplifying the oscillation, and wherein the toner constituent liquid is fed between the thin film and the oscillation surface. | 2008-10-09 |
| 20080248417 | Polyhydric phenol compound and chemically amplified resist composition containing the same - The present invention provides a polyhydric phenol compound represented by the formula (I): | 2008-10-09 |
| 20080248418 | SYNTHESIS OF FLUOROALCOHOL-SUBSTITUTED (METH)ACRYLATE ESTERS AND POLYMERS DERIVED THEREFROM - This invention relates to processes for preparing fluoroalcohol-substituted (meth)acrylate esters. This invention also relates to block copolymers incorporating repeat units derived from fluoroalcohol-substituted (meth)acrylate esters, and photoresists derived therefrom. | 2008-10-09 |
| 20080248419 | POSITIVE RESIST COMPOSITION AND PATTERN FORMING METHOD USING THE SAME - A positive resist composition, includes: (A) a resin that has a group having absorption at 248 nm at a main chain terminal of the resin (A), and a pattern forming method uses the composition. | 2008-10-09 |
| 20080248420 | POSITIVE RESIST COMPOSITION AND PATTERN-FORMING METHOD - A positive resist composition includes: (A) a resin capable of increasing the solubility in an alkali developing solution by the action of an acid, including: (a1) a repeating unit selected from repeating units represented by following formulae (a1-1) to (a1-3); (a2) a repeating unit represented by a following formula (a2); and (a3) a repeating unit selected from repeating units represented by following formulae (a3-1) to (a3-4); (B) a compound capable of generating an acid upon irradiation with actinic ray or radiation; (C) a resin having at least one of a fluorine atom and a silicon atom, and being insoluble in an alkali developing solution; and (D) a solvent, wherein the formulae above are defined in the specification. | 2008-10-09 |
| 20080248421 | POSITIVE RESIST COMPOSITION AND PATTERN FORMING METHOD - A positive photosensitive composition comprises: (A) a resin that has an acid decomposable repeating unit represented by formula (I) and increases its solubility in an alkali developer by action of an acid: (B) a compound generating an acid upon irradiation with actinic light or radiation; (C) a hydrophobic resin insoluble in an alkali developer and having at least either one of a fluorine atom and a silicon atom; and (D) a solvent, | 2008-10-09 |
| 20080248422 | RESIST COMPOSITION, METHOD OF FORMING RESIST PATTERN, COMPOUND AND ACID GENERATOR - A resist composition including a base component (A) and an acid-generator component (B), the acid-generator component (B) including an acid generator (B1) including a compound represented by general formula (b1-8) shown below (wherein R | 2008-10-09 |
| 20080248423 | Chemically amplified resist composition - A chemically amplified resist composition comprising: | 2008-10-09 |
| 20080248424 | Photopolymer Composition Suitable for Lithographic Printing Plates - Radiation-sensitive element comprising (a) a substrate and (b) a radiation-sensitive coating comprising (i) at least one component selected from photoinitiators and sensitizer/coinitiator systems which absorbs radiation of a wavelength in the range of 250 to 1,200 nm; (ii) at least one oligomer A of formula (I) wherein X | 2008-10-09 |
| 20080248425 | POSITIVE RESIST COMPOSITION AND PATTERN-FORMING METHOD - A positive resist composition comprises: (A) a resin that has a repeating unit represented by general formula (a1) and increases its solubility in an alkali developer by action of an acid; (B) a compound which generates an acid upon irradiation with an actinic ray or a radiation; and (C) a resin that has at least one of a fluorine atom and a silicon atom and has a group selected from the group consisting of (x), (y) and (z); and (D) a solvent:
| 2008-10-09 |
| 20080248426 | Antihalation compositions - Antihalation compositions and methods for reducing the reflection of exposure radiation of a photoresist overcoated said compositions. The antihalation compositions of the invention comprise a resin binder and material capable of causing a thermally induced crosslinking reaction of the resin binder. | 2008-10-09 |
| 20080248427 | Composition for Coating over a Photoresist Pattern Comprising a Lactam - The present invention relates to an aqueous coating composition for coating a photoresist pattern comprising a polymer containing a lactam group of structure (1) | 2008-10-09 |
| 20080248428 | Method for Producing Flexographic Printing Forms by Thermal Development - The invention relates to a method for producing flexographic printing forms by thermal development during which a flexographic printing element exposed in an image-like manner is developed by heating and removing the softened, non-polymerized portions of the relief-forming layer, whereby the flexographic printing element used contains a styrene butadiene block copolymer mixed with a softener, and the proportion of butadiene which is 1,2-coupled, ranges from 15 to 50% by weight of the block copolymer. | 2008-10-09 |
| 20080248429 | METHOD OF FORMING A CONTACT HOLE - A method of forming a contact hole is provided. A pattern is formed in a photo resist layer. The pattern is exchanged into a silicon photo resist layer to form a first opening. Another pattern is formed in another photo resist layer. The pattern is exchanged into a silicon photo resist layer to form a second opening. The pattern having the first, and second openings is exchanged into the interlayer dielectric layer, and etching stop layer to form the contact hole. The present invention has twice exposure processes and twice etching processes to form the contact hole having small distance. | 2008-10-09 |
| 20080248430 | Process for preparing a nano-carbon material field emission cathode plate - A nano-carbon material field emission cathode plate is prepared by an oxidation-reduction reaction, which includes immersing a substrate having a first metal layer thereon in a solution of a second metal salt with a nano-carbon material dispersed therein. A difference between the two standard redox potentials of the first metal and the second metal is so great that ions of the second metal in the solution are reduced to elemental metal while the first metal is oxidized, and thus a layer of the second metal is formed on the first metal layer with the nano-carbon material partially embedded in the second metal layer. | 2008-10-09 |
| 20080248431 | PATTERN FORMING METHOD USED IN SEMICONDUCTOR DEVICE MANUFACTURING AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE - A pattern forming method includes forming a first anti-reflection coating on a substrate, the substrate having an uneven surface; forming a second anti-reflection coating on the first anti-reflection coating, the first anti-reflection coating having an uneven surface, and the second anti-reflection coating planarizing the uneven surface of the first anti-reflection coating; forming an intermediate layer film on the second anti-reflection coating; forming a resist film on the intermediate-layer film; patterning the resist film to form a resist pattern; forming an intermediate-layer pattern by etching the intermediate-layer film using the resist pattern as a mask; and forming an under-layer pattern by etching the first and second anti-reflection coatings using the intermediate-layer pattern as a mask. | 2008-10-09 |
| 20080248432 | NEAR-FIELD EXPOSURE METHOD - A near-field exposure method wherein an exposure mask having a light blocking film with an opening smaller than a wavelength of light from an exposure light source is used and wherein an object to be exposed is exposed by near-field light produced at the opening of the exposure mask based on the exposure light from the exposure light source, includes a step of determining a width of the opening so as to satisfy equations (1), (2) and (3) below, where the width of the opening of the exposure mask is denoted by s (nm), a processing pitch of the object to be exposed is denoted by p (nm) and coefficients are denoted by a and b, | 2008-10-09 |
| 20080248433 | PHOTOGRAPHIC ELEMENT CONTAINING A SPEED-ENHANCING COMPOUND - The invention provides a colour photographic element comprising at least one light-sensitive silver halide emulsion layer or a non silver-containing light-insensitive layer, in which at least one of these layers contains a colourless imidazole compound of formula (I) that undergoes less than 10% chemical or redox reaction directly with oxidized developer and which has a partition coefficient to enable the photographic speed of the element to be increased by at least 0.03 stop without increasing granularity, compared to the same element without the compound, wherein the compound of formula: (I) has the structure: wherein X is H or a substituent; Z represents the atoms necessary to complete an unsubstituted or substituted imidazole ring, which may form part of a fused unsubstituted or substituted ring system containing no further ring heteroatoms; wherein there is present at least one —NH group either in the imidazole ring or directly attached to the imidazole ring as part of X; provided that (a) when Z represents the atoms necessary to complete an unsubstituted or substituted benzimidazole ring, an —NH group is directly attached to the imidazole ring as part of X, and X is located between the imidazole nitrogen atoms; (b) when the —N—H group is located in the ring adjacent to the carbon atom bearing X, and X is located between the imidazole nitrogen atoms, the imidazole ring is not fused to a phenanthrene ring. The compounds of formula (I) increase speed without a concomitant increase in size of the light-sensitive silver halide grains. | 2008-10-09 |
| 20080248434 | MAGNETIC LIGHTER - A magnetic lighter, whereby a lighter and at least one magnet material are combined so as to form a magnetic lighter capable of magnetically engaging objects having magnetic properties as well as various accessories. | 2008-10-09 |
| 20080248435 | Devices For High Voltage Ignition of Combustible Gas - High voltage gas igniters are described, including a hand held portable gas torch igniter of the piezoelectric-type which includes a finger grip housing body actuated by inward depression of the push button igniter to generate a spark-producing voltage when held near the combustible gas exiting the bum tube of a torch or combustible gas exit of a heating device. The igniter has a tube electrode for easy construction, and deflector shield for user protection and gas mixing. Other igniters have multiple spark gaps for increased effective spark length. | 2008-10-09 |
| 20080248436 | METHOD OF FILLING LARGE VOIDS WITH CERAMIC FIBER FOAM AND KILN CAR BLOCKS MADE VIA THE SAME - A method of filling cavities in refractory bodies, comprising lofting refractory fibers in flowing air, mixing lofted refractory fibers with refractory foam to generate a fibrous refractory foam, and filling a substantially enclosed cavity in a refractory material with fibrous refractory foam to produce a foam-filled cavity, heating the foam-filled cavity to a first drying temperature for sufficient time to dry the fibrous refractory foam filling, and heating the foam-filled cavity to a second substantially higher firing temperature to produce a fired body. The substantially enclosed cavity is defined by at least one refractory wall. | 2008-10-09 |
| 20080248437 | DETERMINING BRACKET LOCATIONS ON ELECTRONIC MODELS OF TEETH - Locating desired placement locations of brackets for a patient's teeth includes obtaining an array of data points from a cast of the teeth and generating a virtual model from the array of scanned data points. Individual teeth from the virtual model can be manually severed or “cut” and manually dragged from a start position to a finished position to determine a treatment plan. The orthodontist virtually marks the position on the virtual model where a physical bracket is desired. Brackets can then be automatically placed onto a cast of the teeth at corresponding positions. | 2008-10-09 |
| 20080248438 | ORTHODONTIC APPLIANCES AND MATERIALS FOR MAKING SAME - The polymeric shell of a removable dental positioning appliance is formed from transparent polymeric materials having a tensile strength at yield of greater than 6,000 pounds per square inch (psi), an elongation at yield of greater than 4%, an elongation at break of greater than 80%, a tensile modulus greater than 200,000 psi, a flexural modulus greater than 200,000 psi, stress relaxation over time of not more than 50%, and a transmissivity of light between 400 nm and 800 nm greater than 75%. | 2008-10-09 |
| 20080248439 | ORTHODONTIC APPARATUS AND METHOD - An orthodontic device includes a bracket having a body and the body includes external surfaces. An archwire passageway is formed in the body. An aperture extends from one of the external surfaces of the body to the passageway. A pawl is attached to the body and includes stop and cam surfaces which extend into the aperture. An extendable archwire includes an adjustment portion having a locking surface and a loop-spring therein and the adjustment portion is inserted into and through the passageway. The pawl and the locking surface form a ratchet. The cam surface of the pawl interengages the extendable archwire as the extendable archwire is extended through the bracket under the application of force to the extendable archwire. The stop surface of the pawl interengages the locking surface of the adjustment portion of the extendable archwire preventing retraction of the extendable archwire upon discontinuation of the application of force. | 2008-10-09 |
| 20080248440 | Orthodontic Bracket - An orthodontic bracket includes a base, an archwire slot extending through the base, and archwire slot extensions extending substantially in the mesiodistal direction from opposite sides of the base. | 2008-10-09 |
| 20080248441 | ORTHODONTIC IMPLANT - Implant with fastening means ( | 2008-10-09 |
| 20080248442 | ORTHODONTIC BRACE WITH POLYMERIC ARCH MEMBER - A brace for an orthodontic patient includes a polymeric arch member that is removably connected to a series of appliances that are affixed to the patient's teeth. The arch member is preferably made of an aesthetic polymeric material that transmits light and has shape memory properties. Optionally, a sequential set of arch members may be provided to move the teeth in incremental steps toward desired final positions. | 2008-10-09 |
| 20080248443 | Clinician review of an orthodontic treatment plan and appliance - A computer is used to create a plan for repositioning an orthodontic patient's teeth. The computer receives an initial digital data set representing the patient's teeth at their initial positions and a final digital data set representing the teeth at their final positions. The computer then uses the data sets to generate treatment paths along which teeth will move from the initial positions to the final positions. | 2008-10-09 |
| 20080248444 | ULTRASONIC ENDODONTIC TIP HAVING A LOW-MODULUS OF ELASTICITY - An ultrasonic endodontic tip is provided having an elastic modulus of less than 8 Msi. The low-modulus of the material provides the ultrasonic endodontic tip the ability to navigate a curved tooth canal during a root canal procedure and controllably remove the dentine around canal without excessively enlarging the canal. The tip can include an abrasive on at least a portion of the working surface of the tip. | 2008-10-09 |
| 20080248445 | Dental abrasive strip - A abrasive dental filing strip coated with some superfine abrasive material, especially but not limited to diamond dust like particles, or alternatively a sharp cutting system along the lateral surface, and having cutting edge like serrated or saw tooth along the longitudinal edge or edges. | 2008-10-09 |
| 20080248446 | Ultrasonic crown and bridge remover - A dental tool having a pair of opposing jaw members. A biasing mechanism connected to at least one of the jaw members biases the jaw members toward a proximate rest position. A separating mechanism is connected to at least one jaw member for separating the jaw members. An ultrasonic vibrator is connected to the jaw members for vibrating them. Securing means connect the pair of opposing jaw members. | 2008-10-09 |
| 20080248447 | Interproximal Tooth Defects Detection - There is provided a method for detecting interproximal tooth defects such as caries by injecting light at one or more wavelengths into a tooth and detecting reflected/diffracted light or emitted fluorescence. The detected light intensity is characteristic of a healthy or diseased tooth in the interproximal area. | 2008-10-09 |
| 20080248448 | Intra-Radicular Post to Rebuild Teeth with Passage Treatment - An intra-radicular post is described for rebuilding of teeth, with treatment of passages, comprised of one apical portion, a body adjacent to the apical portion, and one head adjacent to the body; characterized because the body is frusto-conical and tapered in such a way that its diameter is greater at the side proximal to the head and lower at the side proximal to the apical portion; apical portion comprises cylindrical segments with a flat end; and the head portion comprises conical segments having at least one flat lateral face; the post having thus improved insertion and retention properties. | 2008-10-09 |
| 20080248449 | Shooting Calibration Systems And Methods - The present invention relates to target acquisition and related systems and devices, and more particularly to telescopic gunsights and associated equipment used to achieve shooting accuracy at, for example, close ranges, medium ranges and extreme ranges. The present invention also provides targets and methods of using the systems to achieve enhanced shooting accuracy. | 2008-10-09 |
| 20080248450 | Method for modeling smoke propagation - A method and computer-readable medium for modeling smoke propagation in a structure are presented, along with applications of the method. A model is provided of a multiplicity of compartments within the structure, and the presence of a fire within a compartment is determined. The energy and smoke released by the fire is estimated, and smoke flows out of the compartment are determined. Each compartment having a smoke source is analyzed, individually, for the propagation of smoke. Each compartment is assumed to have a homogenous upper smoke layer and a lower cool air layer. The analysis includes a mass and energy balance to determine the change in characteristics of the upper smoke layer, where a known pressure for the lower cool air layer is used for the balance. For multiple smoke sources into a compartment, the contributions to the mass and energy balance of each smoke source are considered additive. | 2008-10-09 |
| 20080248451 | Method and apparatus for improved memory retention - A method for improving human memory through the exploitation of the functions of both sides of the human brain that involves the reading of material aloud with one eye and the opposite ear covered and a second reading of the same material aloud with the other eye and the ear opposite the other ear covered and an headset apparatus for the facilitation of said method, with an optional recording mechanism that plays back in the ear of the plugged ear a recording read through a microphone that extends in front of the subject's mouth, said apparatus being usable on both sides of the human subject's head. | 2008-10-09 |
| 20080248452 | Method and apparatus for demonstrating hydrocephalus treatment - Method and apparatus for demonstrating hydrocephalus shunt implantation includes a fabricated body including a fill, a shell covering the fill and including respective torso, head, and valve openings formed in the shell, a simulated torso including the torso opening, and a simulated head including the head and valve openings. An implant includes an abdominal tube attached to the body within the torso opening and a ventricular tube attached to the body within the head opening. An insertion tube is selectively insertable and useable to thread each of the abdominal and ventricular tubes beneath the shell from the respective torso and head openings to the valve opening, for example, along a pocket of the body formed therebetween. The implant can further include a simulated valve connectible to respective free ends of the abdominal and ventricular tubes. The simulated valve can be passable into the body via the valve opening, and a flap can close the valve opening over the simulated valve. | 2008-10-09 |
| 20080248453 | Method of Delivering a Test to a Candidate - The invention relates to a method and apparatus for delivering a test, such a test to a candidate. The invention also concerns an apparatus and method of assessing the relative cognitive ability of a candidate. The invention also concerns a method of assessing the progress of a candidate in response to a learning program. The test, assessing or learning program comprise delivering a series of questions type to a candidate, the questions increasing in difficulty as the candidate successfully completes easier questions, the questions being delivered to the candidate in ranges. The questions may be “Swaps” type questions. The candidate may provide their confidence that their answer to any question is correct. A quantifier may be used to assess the candidates progress and/or cognitive skills. | 2008-10-09 |
| 20080248454 | REMOTE LABS FOR INTERNET-DELIVERED, PERFORMANCE-BASED CERTIFICATION EXAMS - A computer implemented method, apparatus, and computer program product for presenting an internet-delivered, performance-based certification exam to a user. The process requests connection details for a remote computing server in response to receiving a login from the user. The process transmits a web form to the user, wherein the web form presents an objective portion of the certification exam to the user. The process initiates a remote computing client to present a practical portion of the certification exam to the user, and responsive to receiving the completed certification exam from the user, the process calculates a score for the certification exam according to a verification script. | 2008-10-09 |
| 20080248455 | APPARATUS, SYSTEM, AND METHOD FOR REMOTELY CONTROLLING A MULTISCREEN DISPLAY FOR DELIVERY OF INSTRUCTIONAL INFORMATION - An apparatus, system, and method are disclosed for remotely controlling multiple displays for delivery of instructional information from multiple inputs. A setup module is included to store a plurality of display instructions where each display instruction is configured to display at least one image of one or more input devices on each of at least three display devices and each display device capable of displaying a separate image to students in a classroom. A linking module is included to link one or more display instructions with a preset. The preset is located on a remote control device with a plurality of presets. A display module is included to display the images from the input devices on the display devices associated with a display instruction in response to a user selecting the preset linked to the one or more display instructions. | 2008-10-09 |
| 20080248456 | Reorientable Dry Erase Board - This invention relates generally to boards for writing or display, and more particularly to reusable, double sided, reorientable, portable and reconfigurable boards that permit writing to be easily removed. In one embodiment, a writing board comprises a frame, a front panel and a rear panel mounted in the frame, wherein the front panel comprises a first writing surface and the rear panel comprises a second writing surface opposite the first writing surface, wherein the first writing surface and the second writing surface are each adapted to erasably receive writing thereon. The writing board is reorientable to receive erasable writing on the first writing surface and the second writing surface. | 2008-10-09 |
| 20080248457 | Sensor Chip and Manufacturing Method Thereof - Provided are a sensor chip and a manufacturing method of this sensor chip, that includes a substrate, a cover layer, a spacer layer sandwiched between the substrate and the cover layer, and a hollow reaction section between the substrate and the cover layer, wherein warping due to changes in the environmental temperature and humidity does not occur. | 2008-10-09 |
| 20080248458 | Purification, Characterization and Reconstitution of a Ubiquitin E3 Ligase - The present invention provides a native or reconstituted complex comprising Bmi1 and/or Ring1 and/or Ring2, wherein the complex has ubiquitin E3 ligase activity. Optionally, the complex further comprises HPH2 and/or HPC3. Also disclosed are methods of producing the reconstituted complex, methods of identifying compounds that modulate the ubiquitin E3 ligase activity of the native or reconstituted complex, and methods of identifying candidate compounds for treating cancer. Kits for determining modulation of protein ubiquitination and/or for ubiquitinating a target substrate are further provided. | 2008-10-09 |
| 20080248459 | Multiplex detection of agricultural pathogens - Described are kits and methods useful for detection of seven agricultural pathogens (BPSV; BHV; BVD; FMDV; BTV; SVD; and VESV) in a sample. Genomic sequence information from 7 agricultural pathogens was analyzed to identify signature sequences, e.g., polynucleotide sequences useful for confirming the presence or absence of a pathogen in a sample. Primer and probe sets were designed and optimized for use in a PCR based, multiplexed Luminex assay to successfully identify the presence or absence of pathogens in a sample. | 2008-10-09 |
| 20080248460 | Composition and method for modulating an inflammatory response - The invention relates to compositions and methods comprising lymphotoxin-beta receptor (LTβR) modulators, which activate or inhibit LTβR signaling. LTβR modulators are useful for treating lymphocyte mediated immunological diseases and cancer, and more particularly, for regulating mitochondrial-mediated apoptosis. This invention relates to soluble forms of the LTβR complex proteins that act as LTβR activating or inhibiting agents. This invention also relates to the use of soluble molecules, directed against either the LTβR, its ligands, LIGHT and LTβ1α2, or its intracellular binding partners, that function to regulate LTβR signaling. A novel screening method for selecting soluble receptors, antibodies and other agents that modulate LTβR signaling is provided. | 2008-10-09 |
| 20080248461 | PNA Probes, Kits, and Methods for Detecting Genotypes of Human Papillomavirus - Disclosed are PNA probes capable of genotype specifically binding with Human Paillomavirus (HPV) DNA, kits for detecting HPV genotypes comprising the probes, and methods for detecting HPV genotypes by using the kits, which enables the accurate detection of all 24 genotypes of HPV found in cervix, diagnosis of combined infection with more than one HPV genotype, and detection of HPV genotypes with high specificity and sensitivity. | 2008-10-09 |
| 20080248462 | Diagnostics and Therapeutics for Diseases Associated with Arginyl Aminopeptidase (Aminopeptidase B)-Like 1 (Rnpepl1) - The invention provides a human RNPEPL1 which is associated with the cardiovascular diseases, endocrinological diseases, metabolic diseases, cancer, inflammation, gastroenterological diseases, hematological diseases, respiratory diseases, neurological diseases, urological diseases and reproduction disorders. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases, endocrinological diseases, metabolic diseases, cancer, inflammation, gastroenterological diseases, hematological diseases, respiratory diseases, neurological diseases, urological diseases and reproduction disorders. The invention also features compounds which bind to and/or activate or inhibit the activity of RNPEPL1 as well as pharmaceutical compositions comprising such compounds. | 2008-10-09 |
| 20080248463 | Split Enzyme Linked Immunosorbent and Nucleic Acid Assays - A method for detecting the presence of an analyte in a solution. The analyte includes at least two mutually exclusive recognition sites that are capable of binding to corresponding recognition molecules. Biosensors are provided that include the recognition molecules, which are attached to the inactive portions of a split enzyme. The recognition sites are located such that the inactive enzyme portions combine to form a detectable biologically active enzyme when the recognition molecules bind to recognition sites. | 2008-10-09 |
| 20080248464 | Method of DNA Shuffling with Polynucleotides Produced by Blocking or Interrupting a Synthesis or Amplification Process - Disclosed is a process of performing “sexual” PCR which includes generating random polynucleotides by interrupting or blocking a synthesis or amplification process to show or halt synthesis or amplification of at least one polynucleotide, optionally amplifying the polynucleotides, and reannealing the polynucleotides to produce random mutant polynucleotides. Also provided are vector and expression vehicles including such mutant polynucleotides, polypeptides expressed by the mutant polynucleotides and a method for producing random mutant polypeptides. | 2008-10-09 |
| 20080248465 | Polymorphisms in the Fcgr2b Promoter and Uses Thereof - The invention relates to the FCGR2B gene and its promoter. In particular, the invention relates to FCGR2B promoters with specific nucleotides at polymorphic sites. Characterization of the nucleotides at polymorphic sites is useful for characterizing the gene and the protein and is useful for determining predisposition or susceptibility to certain diseases and infections in a subject or a population of subjects. Such characterization of the gene or protein is also useful for determining immunoresponsiveness or responsiveness to therapeutic agents in a subject or population of subjects. Thus, disclosed herein are a variety of related nucleic acids, methods and tools. | 2008-10-09 |
| 20080248466 | Method Of Detecting Mutations In The Gene Encoding Cytochrome P450-2C19 - The present invention describes a method for the simultaneous identification of two or more mutations located in the gene encoding Cytochrome P450-2C19. Multiplex detection is accomplished using multiplexed tagged allele specific primer extension (ASPE) and hybridization of such extended primers to a probe, preferably an addressable anti-tagged support. | 2008-10-09 |
| 20080248467 | System for pulling out regulatory elements using yeast - Disclosed are methods for identifying molecular interactions between DNA sequences and proteins in vivo. The methods of the invention employ known or suspected DNA-binding proteins and genomic DNA in a plasmid library. Interacting molecules direct the expression of a reporter gene, the expression of which is then assayed. Also disclosed are genetic constructs useful in practicing the methods of the invention. | 2008-10-09 |
| 20080248468 | Method for Improved Selection of Rnai Transfectants - The present invention is directed to a method for inactivation of expression of a gene in a eucaryotic cell comprising (i) transfection of a eucaryotic cell with DNA comprising an expression cassette for expression of a cell surface protein and an expression cassette for expression of a RNAi compound, said compound being capable of inactivating expression of said gene, wherein said expression cassette for expression of a cell surface protein and said expression cassette for expression of a RNAi compound are located on the same vector DNA, and (ii) enrichment and/or selection of cells which express said cell surface protein. | 2008-10-09 |
| 20080248469 | Methods for Identifying Nucleotides of Interest in Target Polynucleotides - In some embodiments, the present teachings provide a method of identifying a nucleotide of interest in a target polynucleotide. In some embodiments, the method can comprise forming an amplification strand, wherein the amplification strand comprises a hairpinning end region; hybridizing the hairpinning end region of the amplification strand with a hairpinning region of a target polynucleotide, to form a self-complementary amplification product. After performing an extension reaction, wherein the hairpinning end region of the amplification strand is extended, an extended reaction product is formed. Detection of the extended reaction product can result in the identification of a nucleotide of interest in the target polynucleotide. Additional methods, as well as kits, are also provided. | 2008-10-09 |
| 20080248470 | GENETIC SCREENING FOR PREDICTING ANTIDEPRESSANT DRUG RESPONSE BASED ON THE MONOAMINE TRANSPORTER GENE POLYMORPHISM COMBINATION - The present invention discloses is a method of selecting a drug based on personal genetic information when prescribing an antidepressant for a depressed patient. According to the invention, either a noradrenaline reuptake inhibitor (NRI) antidepressant or a selective serotonin reuptake inhibitor (SSRI) antidepressant can be selected based on the combination of monoamine transporter gene polymorphisms, that is, NET G1287A polymorphism in a norepinephrine transporter (NET) gene, serotonin transporter gene (5-HTT) promoter polymorphism and 5-HTT gene intron 2 polymorphism. Also, based on the norepinephrine transporter gene NET G1287A polymorphism alone, the noradrenaline reuptake inhibitor (NRI) antidepressant can be selected. | 2008-10-09 |
| 20080248471 | Methods for disease detection - The present invention provides methods for detecting disease by analysis of a patient sample to determine the integrity of nucleic acids in the sample. | 2008-10-09 |
| 20080248472 | Method and Kit for Determination of Thymidine Kinase Activity and Use Thereof - A method and assay kit for determination of thymidine kinase (TK) activity in a biological sample, such as blood, serum, plasma, Cerebral Spinal Fluid (CSF), pleural fluid, ascites, tissues, cells and extracts thereof, is described. The method comprises contacting, in a buffer, a Basic Reaction Mixture comprising: solid surface-attached primer and/or template, a modified deoxy nucleoside, such as BromodeoxyUridine, IododeoxyUridine, Fluorodeoxy-Uridine or VinyldexoyThymidine as a kinase enzyme substrate, a phosphate donor, a nucleotide polymerizing enzyme, and a kinase enzyme source devoid of TK activity, such as a yeast extract, with the biological sample. After incubation the amount of modified deoxy nucleoside that has been incorporated into the solid surface-attached primer and/or template, is determined and the TK activity present in the biological sample is directly proportional to the amount of incorporated modified deoxy nucleoside. The method and assay kit are useful in the diagnosing, prognosis monitoring of disease progression and treatment effects of cell-proliferation disorders or diseases, such as cancer, and in the screening of compounds, e.g. new drug candidates, affecting enzymatic pathways, which may obstruct the formation of thymidine phosphates or interfere with nucleic acid synthesis. | 2008-10-09 |
| 20080248473 | Method and Kit for the Detection of Bacterial Species by Means of Dna Analysis - The present invention relates to the detection and identification of different bacterial species, all of which cause zoonosis, based on DNA analysis. More specifically, the invention provides the primers, probes, genes and genic regions required to apply a method for the simultaneous detection of bacteria and bacterial groups belonging to the genera | 2008-10-09 |
| 20080248474 | AMPLIFICATION METHODS - Methods are provided for amplification and monitoring of oligonucleotide amplification in which a primer has an overlap with one or more bases of a detection probe. | 2008-10-09 |
| 20080248475 | Methods and Compositions for Modulating Gluconeogenesis Using PGC-1 - The invention provides novel methods and compositions for modulating gluconeogenesis through modulation of PGC-1 activity or expression. Also provided are methods for identifying compounds that modulate gluconeogenesis through modulation of PGC-1 activity or expression, as well as methods for identifying compounds that modulate the interaction of PGC-1 with PGC-1 target molecules. Further provided are methods for treating disorders characterized by aberrant gluconeogenesis. | 2008-10-09 |
| 20080248476 | Genetic polymorphisms associated with myocardial infarction, methods of detection and uses thereof - The present invention is based on the discovery of genetic polymorphisms that are associated with myocardial infarction. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection. | 2008-10-09 |
| 20080248477 | Novel ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST protein and nucleic acid molecules and uses therefor - Novel ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST proteins, the invention further provides isolated ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST fusion proteins, antigenic peptides and anti-ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST antibodies. The invention also provides ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which an ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided. | 2008-10-09 |
| 20080248478 | MOLECULAR HISTOLOGICAL ANALYSIS OF MULTICELLULAR SAMPLES - The present invention provides modified digital images of a multicellular sample using molecular profiles of cells from said multicellular sample for a molecular histological analysis. | 2008-10-09 |
| 20080248479 | Methods for Isolating and Characterizing Endogenous mRNA-Protein (mRNP) Complexes - Cellular mRNA-protein (mRNP) complexes are partitioned in vivo by contacting a biological sample with at least one ligand that specifically binds at least one component of a mRNP complex. Suitable biological samples comprise at least one mRNA-protein (mRNP) complex and include cell cultures, cell extracts, and whole tissue, including tumor tissue. Ligands include antibodies that specifically bind RNA-binding or RNA-associated proteins present in the mRNP complex. The mRNP complex is separated by binding the ligand with a binding molecule specific for the ligand, where the binding molecule is attached to a solid support. The mRNP complex is collected by removing the mRNP complex from the solid support. After collecting the mRNP complex, the mRNA bound within the complex may be characterized and identified. Subsets of the total mRNA population of a cell may accordingly be characterized, and a gene expression profile of the cell obtained. | 2008-10-09 |
| 20080248480 | Novel nucleotide mixture for improved nucleic acid amplification performance - The present invention relates to modification of amplification buffer used in amplification reactions. The modifications result in a significant improvement in results of amplification. In particular, the present invention provides methods and buffers for performing an amplification reaction utilizing a buffer comprising nucleotide triphosphates comprising treating the buffer to substitute a portion of the nucleotide triphosphates with nucleotide diphosphates. | 2008-10-09 |
| 20080248481 | METHODS OF EVALUATING CELLS AND CELL CULTURES - Methods of evaluating the composition of a cell culture (e.g., to distinguish chondrocytes from fibroblasts) and methods for evaluating the phenotype of an individual cell (e.g., as a chondrocyte) are disclosed. The methods may be used, for example, for assessing chondrocyte cultures used for treatment of cartilage defects. In some embodiments, the invention involves identifying cell culture composition or the identity of a cell based on expression level of a fibroblast marker. In other embodiments, the invention involves comparing expression levels of at least one chondrocyte marker and at least one fibroblast marker in a cell culture sample or in an individual cell. In illustrative embodiments, the chondrocyte marker is hyaluronan and proteoglycan link protein 1 (HAPLN1), and the fibroblast marker is microfibrillar associated protein 5 (MFAP5). | 2008-10-09 |
| 20080248482 | BIOMARKERS FOR TOXIC ALGAE - The present invention is directed toward biomarkers that identify characteristics of algae. The invention is further directed toward biomarkers that serve to identify algae species and strains of algae species as well as detect the presence of algal toxins. Additional embodiments feature methods utilizing algal biomarkers and polypeptides that can serve as biomarkers. | 2008-10-09 |
| 20080248483 | METHODS OF IDENTIFYING THERAPEUTIC COMPOUNDS IN A GENETICALLY DEFINED SETTING - The invention provides a method of identifying therapeutic compounds in a genetically defined setting. The method consists of contacting a cell indicative of a pathological condition from a diseased individual and a cell from a genetically related normal individual with a plurality of candidate therapeutic compounds under suitable assay conditions, and identifying a compound that preferentially alters a predetermined property of the cell from the diseased individual. | 2008-10-09 |
| 20080248484 | METHOD FOR THE EARLY DETECTION OF PANCREATIC CANCER AND OTHER GASTROINTESTINAL DISEASE CONDITIONS - The present invention uses peripheral blood monocyte-lymphocyte for the early diagnosis of pancreatic cancer, as well as other conditions of the pancreas and other organs. The peripheral blood lymphocytes recognize the new neoplasm in the pancreas, as well as disease processes in other organ systems. The evaluation of this specific recognition of the disease process by the peripheral blood monocyte-lymphocyte through gene microarray expression patterns constitute a successful method for the early detection of pancreatic cancer and other organ disease processes. This document describes the process used in this method of early diagnosis. | 2008-10-09 |
| 20080248485 | Radiolabeled 3-[3- (Benzoyl-Amido) Benzyloxy] Aspartic Acid Derivative and Method of Producing the Same - The present invention provides a radiolabeled ligand which is highly selective and potent for glutamate transporters and is usable in specifically detecting the glutamate transporter. | 2008-10-09 |
| 20080248486 | Type Pept1 Protein Assay - The present invention relates to a type PepT1 protein assay and in particular a process for identifying a substrate and/or a modulator of the PepT1 protein. | 2008-10-09 |
| 20080248487 | MODULATION OF PROTEIN FUNCTIONALITIES - New methods for the rational identification of molecules capable of interacting with specific naturally occurring proteins are provided, in order to yield new pharmacologically important compounds and treatment modalities. Broadly, the method comprises the steps of identifying a switch control ligand forming a part of a particular protein of interest, and also identifying a complemental switch control pocket forming a part of the protein and which interacts with said switch control ligand. The ligand interacts in vivo with the pocket to regulate the conformation and biological activity of the protein such that the protein assumes a first conformation and a first biological activity upon the ligand-pocket interaction, and assumes a second, different conformation and biological activity in the absence of the ligand-pocket interaction. Next, respective samples of said protein in the first and second conformations are provided, and these are screened against one or more candidate molecules by contacting the molecules and the samples. Thereupon, small molecules which bind with the protein at the region of the pocket maybe identified. Novel protein-modulator adducts and methods of altering protein activity are also provided. | 2008-10-09 |
| 20080248488 | Platelet-Derived Microparticles as a Novel Diagnosis Maker for a Cardiovascular Disease - The present invention relates to a diagnosis maker for a cardiovascular disease comprising platelet-derived microparticles. The present invention also relates to a method for diagnosing a cardiovascular disease in a subject with symptoms of cardiovascular disease or suspected of having cardiovascular disease, wherein said method comprises: (a) obtaining a sample from said subject; (b) reacting an antibody to platelet-derived microparticles or a fragment thereof with a biological sample; (c) detecting a presence or an absence of the platelet-derived microparticles or a fragment thereof in said sample; and (d) diagnosing cardiovascular disease in said subject having said symptoms when said platelet-derived microparticles or a fragment thereof are detected in said sample. | 2008-10-09 |
| 20080248489 | METHODS AND COMPOSITIONS FOR DIRECTED MICROWAVE CHEMISTRY - The present invention concerns a novel means by which specific chosen reactions can be accelerated through the use of a new type of artificial enzyme. The invention allows specific reactions to occur at an accelerated rate, even in the presence of other non-chosen molecules, which may be very similar in structure to the chosen reactant. The reactions may be stoichiometric or catalytic. | 2008-10-09 |
| 20080248490 | Reagents for the detection of protein phosphorylation in Leukemia signaling pathways - The invention discloses nearly 288 novel phosphorylation sites identified in signal transduction proteins and pathways underlying human Leukemia, and provides phosphorylation-site specific antibodies and heavy-isotope labeled peptides (AQUA peptides) for the selective detection and quantification of these phosphorylated sites/proteins, as well as methods of using the reagents for such purpose. Among the phosphorylation sites identified are sites occurring in the following protein types: Adaptor/Scaffold proteins, Cytoskeletal proteins, Cellular Metabolism enzymes, G Protein/GTPase Activating/Guanine Nucleotide Exchange Factor proteins, Immunoglobulin Superfamily proteins, Inhibitor proteins, Lipid Kinases, Nuclear DNA Repair/RNA Binding/Transcription proteins, Serine/Threonine Protein Kinases, Tyrosine Kinases, Protein Phosphatases, and Translation/Transporter proteins. | 2008-10-09 |
| 20080248491 | BIOMARKER FRAGMENTS FOR THE DETECTION OF HUMAN BNP - The present invention relates among other things to a composition comprising at least two (2) human BNP fragments, wherein each of the human BNP fragments of the composition are cross-linked to at least one of the other human BNP fragments of the composition. | 2008-10-09 |
| 20080248492 | Membrane Based Assays - Membrane-based assays using surface detector array devices suitable for use with a biosensor are disclosed. The device is formed of a substrate having a surface defining a plurality of distinct bilayer-compatible surface regions separated by one or more bilayer barrier regions. The bilayer-compatible surface regions carry on them, separated by an aqueous film, supported fluid bilayers. The bilayers may contain selected receptors or biomolecules. A bulk aqueous phase covers the bilayers on the substrate surface. Arrays may be engineered to display natural membrane materials in a native fluid bilayer configuration, permitting high-throughput discovery of drugs that target and affect membrane components. The membrane-based assays detect binding events by monitoring binding-induced changes in one or more physical properties of fluid bilayers. | 2008-10-09 |
| 20080248493 | ACRIDINIUM PHENYL ESTERS USEFUL IN THE ANALYSIS OF BIOLOGICAL SAMPLES - The present invention relates to methods and kits for detecting an analyte in a test sample using acridinium-9-carboxylate aryl esters. | 2008-10-09 |
| 20080248494 | Test Methods and Devices - A method and test device for differentiating between states of an analyte that can exist in different forms, such as follicle stimulating hormone (FSH). The method or test device uses two contemporaneous assays, the first of which does not differentiate between the two analyte states and the second of which does, and the assay results are compared. A novel pair of anti-FSH monoclonal antibodies that can be used together in a sandwich-format assay to differentiate pre-menopausal and post-menopausal FSH samples is disclosed. | 2008-10-09 |
| 20080248495 | Guinea pig proteinase-activated receptor 4 and its activating peptide - This invention relates to nucleic acid encoding guinea pig PAR 4 and to the protein encoded thereby. The guinea pig DNA and protein are useful for the development of models of human platelet aggregation. The invention further relates to an animal model to assess the role of PAR antagonists in thrombosis. | 2008-10-09 |
| 20080248496 | NUCLEAR MATRIX PROTEIN ALTERATIONS ASSOCIATED WITH COLON CANCER AND COLON METASTASIS TO THE LIVER, AND USES THEREOF - Proteins useful in the diagnosis of proliferative disorders of the colon are present in nuclear matrix protein preparations and can be characterized by molecular weight, isoelectric point, and amino acid sequence. The proteins may be identified, for example, by 2D-gel electrophoresis or by specific binding partners, such as antibodies. | 2008-10-09 |
| 20080248497 | Detection of Anaplasma platys - The invention provides compositions and methods for the detection of | 2008-10-09 |
| 20080248498 | METHODS AND COMPOSITIONS TO DIAGNOSE TRICHOMONAS INFECTION - The present invention provides methods and compositions for diagnosing | 2008-10-09 |
| 20080248499 | Methods and Apparatus for the Isolation and Enrichment of Circulating Tumor Cells - Embodiments in accordance with the present invention relate to methods and apparatuses for concentrating and isolating Circulating Tumor Cells (CTCs) from body fluids. One embodiment of the present invention includes a micro-fabricated or nano-fabricated device having channels configured for separating and excluding. Embodiments in accordance with the present invention utilize features that reduce the hydrodynamic pressure experienced by the cells during the separation, isolation and concentration processes, and therefore reduce the likelihood of cell lysis or other damage to the cells. | 2008-10-09 |
| 20080248500 | Apolipoprotein A-II Isoform As A Biomarker For Prostate Cancer - The present invention provides a protein-based biomarker, ApoA-II isoform, that is useful in determining prostate cancer status in a patient. In particular, the biomarker of this invention is useful to classify a biological sample as prostate cancer or non-prostate cancer. The ability of ApoA-II to detect disease in patients with a normal prostate-specific antigen (PSA) makes the biomarker of this invention useful in identifying indolent disease. The biomarker can be detected by SELDI mass spectrometry, HPLC, PAGE and Western blotting. | 2008-10-09 |
| 20080248501 | Methods of Diagnosing Ovarian Cancer and Kits Therefor - A method for the diagnosis of ovarian cancer comprising providing a biological sample from a subject (subject sample), and detecting the expression level of each of the markers FGF-2, CA 125 and IL-18 in the subject sample A kit comprising means for detection of an expression level of each of the markers CA 125, FGF-2 and IL-18 in a biological sample from a subject (subject sample), and instructions to use said markers in a method of the present invention. | 2008-10-09 |
