41st week of 2015 patent applcation highlights part 23 |
Patent application number | Title | Published |
20150284627 | PDMS-BASED LIGANDS FOR QUANTUM DOTS IN SILICONES - The invention provides a process for the production of a wavelength converter containing a siloxane polymer matrix with wavelength converter nano particles embedded therein, the process containing (a) mixing (i) a first liquid containing (i1) short chain siloxane polymers and (i2) wavelength converter nano particles having an outer surface grafted with siloxane grafting ligands and (ii) curable siloxane polymers, and (b) curing the curable siloxane polymers, thereby producing the wavelength converter ( | 2015-10-08 |
20150284628 | Coatings for Photoluminescent Materials - The teachings are generally directed to phosphors having combination coatings with multifunctional characteristics that increase the performance and/or reliability of the phosphor. The teachings include highly reliable phosphors having coatings that contain more than one inorganic component, more than one layer, more than one thicknesses, more than one combination of layers or thicknesses, a gradient-interface between components, a primer thickness or layer to inhibit or prevent leaching of phosphor components into the coatings, a sealant layer to inhibit or prevent entry of moisture or oxygen from the environment, a mixed composition layer as a sealant and multifunctional combination coatings. | 2015-10-08 |
20150284629 | Nitride Phosphors with Interstitial Cations for Charge Balance - Phosphors comprising a nitride-based composition represented by the chemical formula: M | 2015-10-08 |
20150284630 | ALUMINATE LUMINESCENT MATERIAL AND PREPARATION METHOD THEREFOR - An aluminate luminescent material with a general molecular formula of Y | 2015-10-08 |
20150284631 | SILICATE LUMINESCENT MATERIAL AND PREPARATION METHOD THEREFOR - The present invention provides a silicate luminescent material, wherein said silicate luminescent material has a general molecular formula of Li | 2015-10-08 |
20150284632 | Liquid Crystal Compound Containing Cyclobutyl Group and Difluoromethyleneoxy Linking Group, and Preparation Method and Use Thereof - A liquid crystal compound containing cyclobutyl and a linking group difluoromethyleneoxy, and a preparation method and use thereof are disclosed. The compound is as shown in Formula I. The liquid crystal compound containing cyclobutyl as a terminal group and difluoromethyleneoxy (—CF | 2015-10-08 |
20150284633 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY - A liquid crystal composition includes a first compound represented by following Chemical Formula 1, a second compound represented by following Chemical Formula 2, and at least one of a third compound represented by following Chemical Formula 3 and a fourth compound represented by following Chemical Formula 4. | 2015-10-08 |
20150284634 | NEMATIC LIQUID CRYSTAL COMPOSITION - A liquid crystal composition having positive dielectric anisotropy and sufficiently low viscosity without decreasing refractive index anisotropy or increasing nematic phase-isotropic liquid phase transition temperature, and prevents display failures is provided. The liquid crystal composition comprises one or more compounds selected from compounds represented by general formula (LC0) and one or more compounds selected from the group of compounds represented by general formula (LC1) to general formula (LC5), wherein the liquid crystal composition comprises one or more compounds in which at least one of A | 2015-10-08 |
20150284635 | LIQUID-CRYSTALLINE MEDIUM AND ELECTRO-OPTICAL LIQUID-CRYSTAL DISPLAY - The invention relates to an electro-optical liquid-crystal display having a re-alignment layer for the re-alignment of the liquid crystals whose field has a component, crucial for the re-alignment, parallel to the liquid-crystal layer, containing a liquid-crystalline medium, characterised in that it contains at least one compound of the formula (I), at least one compound of the formula (II), and at least one compound of the formula (III), in which the parameters R | 2015-10-08 |
20150284636 | LIQUID-CRYSTALLINE MEDIUM AND ELECTRO-OPTICAL LIQUID-CRYSTAL DISPLAY - The invention relates to an electro-optical liquid-crystal display having a re-alignment layer for re-alignment of the liquid crystals whose field has a component, crucial for the re-alignment, parallel to the liquid-crystal layer, containing a liquid-crystalline medium, characterised in that it comprises one or more compounds of the formula I1 to I3, (I1) (I2) (I3) and at least one compound of the formula II, in which the parameters R | 2015-10-08 |
20150284637 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE - A liquid crystal composition and an AM LCD device including the same are described. The liquid crystal composition has a negative dielectric anisotropy and contains a specific compound having a large negative dielectric anisotropy as a first component and a compound having a large optical anisotropy as a second component, and may further contain a specific compound having a high maximum temperature or a small viscosity as a third component, a specific compound having a large negative dielectric anisotropy as a fourth component, and/or a specific compound having a polymerizable group as an additive component. | 2015-10-08 |
20150284638 | FIREPROOF COMPOSITION AND FIREPROOF THERMAL INSULATION BOARD - Disclosed are a fireproof composition and a fireproof thermal insulation board containing the fireproof composition. The fireproof composition comprises by weight: a thermosetting resin of 30-65 parts, an inorganic flame retardant of 15-45 parts, a flame retardant structure reinforcer of 2-25 parts, a solvent of 5-15 parts and a curing agent of 2-6 parts, wherein the curing agent is separately packaged and is added before use. The fireproof thermal insulation board comprises foamed plastic particles and the fireproof composition bonding with the foamed plastic particles. The fireproof thermal insulation board has thermal insulation features, prevents burning at high temperature and collapse at high temperature, and reduces poisonous black smoke. | 2015-10-08 |
20150284639 | METHOD FOR CONVERTING CARBON AND HYDROCARBON CRACKING AND APPARATUS FOR HYDROCARBON CRACKING - A method for converting carbon into a carbon oxide, comprises: contacting carbon with steam in presence of a carnegieite-like material of formula (Na | 2015-10-08 |
20150284640 | METHOD FOR PRODUCING HIGH VCM COKE - A process and apparatus for improving the production of coke having a high volatile combustible material content are disclosed. The process may include, for example: heating a coker feedstock to a coking temperature to produce a heated coker feedstock; contacting the heated coker feedstock with a quench medium to reduce a temperature of the heated coker feedstock and produce a quenched feedstock; feeding the quenched feedstock to a coking drum; subjecting the quenched feedstock to thermal cracking in the coking drum to (a) crack a portion of the quenched feedstock to produce a cracked vapor product, and (b) produce a coke product having a volatile combustible material (VCM) concentration in the range from about 13% to about 50% by weight, as measured by ASTM D3175. | 2015-10-08 |
20150284641 | METHOD AND APPARATUS FOR CONTROLLING CATALYST IN REACTION ZONES AND PURIFYING AND COOLING REGENERATED CATALYST - A process and an apparatus used in the catalytic reaction process with feed of petroleum hydrocarbons or alcohols for controlling catalyst in reaction zones, purifying, heat transferring and cooling regenerant are provided. The apparatus comprises a catalyst regenerator, an external heat exchanger, a purifying controller for regenerant, a reactor and catalyst conveying pipes. The regenerator is connected with the external heat exchanger and the purifying controller for regenerant respectively, and the purifying controller for regenerant is connected with the reactor via two conveying pipes. The process for controlling reaction and catalyst participating in the reaction comprises the following parts: controlling contact gasification reaction of liquid phase feed, controlling gas phase reaction, at first withdrawing the regenerant from the purifying controller and removing nitrogen, oxygen, carbon dioxide and gaseous impurities carried with the regenerant, then feeding the regenerant into the reactor under the feeding point of feed and above the gasification contact zone after the control temperature reached the reaction requirement. The three-level control of the reactor, before reaction, after liquid phase gasification reaction and outlet reaction conditions of the reactor, is realized, while nitrogen and oxygen carried with the regenerant are limited to fed into the reactor. The yield of products is improved. | 2015-10-08 |
20150284642 | SULFONE CRACKING USING SUPERCRITICAL WATER - A process for employing supercritical water, optionally in the presence of a catalyst, for the cracking of sulfones sulfoxides and mixtures thereof, which have been recovered and separated after the oxidative desulfurization of a stream of crude oil or distilled fractions thereof. | 2015-10-08 |
20150284643 | SINGLE STEP CATALYTIC PROCESS FOR THE CONVERSION OF N-PARAFFINS AND NAPHTHA TO DIESEL RANGE HYDROCARBONS - The present invention discloses a single step catalytic process for the conversion of n-paraffins and naphtha to diesel range hydrocarbons. A bi-metallic Pt—Sn/ZSM-5 catalyst has been developed for the direct conversion of n-heptane as well as naphtha into diesel range hydrocarbons in a single step process. | 2015-10-08 |
20150284644 | PROCESS FOR PRODUCTION OF LIGHT OLEFINS AND BTX USING AN FCC UNIT PROCESSING A HEAVY FEEDSTOCK OF THE HIGHLY HYDROTREATED VGO TYPE, COUPLED WITH A CATALYTIC REFORMING UNIT AND AN AROMATIC COMPLEX PROCESSING A NAPHTHA-TYPE FEEDSTOCK - The present invention relates to the FCC units processing heavy feedstocks enriched with hydrogen, such as for example a highly hydrotreated VGO, or the unconverted part at the end of hydrocracking this same type of VGO feedstock, feedstocks which have the characteristic of cracking to light olefins such as ethylene and propylene. The integration of an FCC with an aromatic complex allows the recovery by the aromatic complex of the BTX formed in the FCC, and the recovery by the FCC from the flow at the bottom of the column, of heavy aromatics from the aromatic complex. | 2015-10-08 |
20150284645 | PROCESS FOR PREPARING OLEFIN-CONTAINING PRODUCTS BY THERMAL STEAM CRACKING - A process for preparing olefinic products by thermal steam cracking of a first furnace feed composed of hydrocarbons in at least one first cracking furnace and of a second furnace feed composed of hydrocarbons in at least one second cracking furnace. The first furnace feed is at least partly converted into a first product stream in the first cracking furnace and the second furnace feed is at least partly converted into a second product stream in the second cracking furnace. A first pyrolysis oil is isolated from the first product stream and is at least partly treated chemically. The first pyrolysis oil is at least partly recirculated as furnace feed from downstream of the chemical treatment to the first cracking furnace. The first cracking furnace and the second cracking furnace are operated under different cracking conditions. | 2015-10-08 |
20150284646 | PROCESS FOR THE PRODUCTION OF LIGHT OLEFINS AND BTX USING A CATALYTIC CRACKING UNIT, NCC, PROCESSING A NAPHTHA TYPE FEED, A CATALYTIC REFORMING UNIT AND AN AROMATICS COMPLEX - The present invention concerns a process for the production of light olefins and BTX using a catalytic cracking unit, NCC, processing a naphtha type feed, and an aromatics complex. It can be used to exploit the synergies between these two units. The thermal balance of the NCC, which is intrinsically deficient in coke, is resolved by the optimal use of heat from the reforming furnaces in order to preheat the feed for the NCC, and by introducing at least a portion of the raffinate obtained from the aromatics complex as a mixture with the naphtha. | 2015-10-08 |
20150284647 | WTE-PROCESSES AND RENEWABLE ENERGY OPTIMIZATION SYSTEM - The present disclosure encompasses systems, machinery, and processes for handling municipal, solid waste mixtures through which this material is recycled into renewable energy. The system comprises three processes: a waste handling process, a recycling and transforming process that converts the waste into fuel, and an energy renewal process. The waste handling process includes collection, sorting, an sizing of the mixed waste; the recycling and transforming process converts collected material into RDF (refuse derived fuel) pellets, and the energy renewal process comprises decomposition of mixture rich in organic matter using biogas/anaerobic technology to collect methane gas and biogas residues, and gasification of the solid RDF pellets, converting them into renewable energy and synthetic carbon. | 2015-10-08 |
20150284648 | TEMPERATURE MONITORING IN A GASIFICATION REACTOR - A gasification reactor for the partial combustion of a carbonaceous feed comprising a gasifier having a gasifier wall, and a method for monitoring temperature development in the gasifier. the gasifier wall comprises coolant lines. At least one of the coolant lines is a temperature monitoring line connected to a supply of a liquid coolant, in particular water. The temperature monitoring line comprises temperature measuring units for measuring temperature change over at least a section of the temperature monitoring line, where the coolant temperature is below the coolant boiling point. | 2015-10-08 |
20150284649 | Methods and Compositions for the Recombinant Biosynthesis of N-Alkanes - The present disclosure identifies methods and compositions for modifying photoautotrophic organisms as hosts, such that the organisms efficiently convert carbon dioxide and light into n-alkanes, and in particular the use of such organisms for the commercial production of n-alkanes and related molecules. | 2015-10-08 |
20150284650 | N-MONOMETHYL-SUBSTITUTED ANILINES AS COMPONENTS INCREASING THE OXIDATIVE RESISTANCE OF PETROL - The invention relates to application of N-monomethyl-4-methoxyaniline, N-monomethyl-4-ethoxyaniline and N-monomethyl aniline and their mixtures as oxidation-preventive additives for engine fuel. This invention may be used to improve their performance parameters. It also relates to fuel compositions containing the above-mentioned chemical compounds. | 2015-10-08 |
20150284651 | Method and Apparatus for Generating a Methane-Containing Substitute Natural Gas and Related Energy Supply System - The invention relates to a method and an apparatus for generating a methane-containing substitute natural gas from a carbon oxide-containing input gas and also to an energy supply system equipped with such an apparatus. According to the invention, the input gas is subjected to a methanation reaction where a superstoichiometric hydrogen fraction is established in the reactant gas. The product gas of the methanation reaction is divided by gas separation into a methane-containing retentate gas, which yields the substitute natural gas, and a hydrogen-containing permeate gas. At least some of the permeate gas is returned to the input gas and admixed therein to form the reactant gas for the methanation reaction. The invention may be used, for example, for renewable energy supply systems with biomass valorization. | 2015-10-08 |
20150284652 | DIESEL FUEL WITH IMPROVED IGNITION CHARACTERISTICS - Diheterocyclo diazene dicarboxamides have been found to effectively reduce the ignition delay and/or as effective cetane number improvers in diesel fuels and is suitable for use in modern engines. | 2015-10-08 |
20150284653 | THERMALLY STABLE SELF-LUBRICATING COATINGS - In some examples, an article includes a substrate and a coating on the substrate. The coating includes a stabilized microstructure including Magnéli oxide phase including an oxide of at least one of W, Mo, Nb, Ta, or Re. In some examples, a technique may include forming a coating including a refractory metal on a surface of a substrate. The technique also may include heat treating the coating at a temperature between about 500° C. and about 700° C. to form a coating including a stabilized microstructure including Magnéli oxide phase. The stabilized microstructure including Magnéli oxide phase may include an oxide of at least one of W, Mo, Nb, Ta, or Re. In some examples, the coating including the stabilized microstructure including Magnéli oxide phase exhibits a coefficient of friction that is at least 25% less than the coefficient of friction exhibited by the as-deposited coating under similar conditions. | 2015-10-08 |
20150284654 | HYDROPHOBIC AND HYDROPHILIC INTERPENETRATING POLYMER NETWORKS DERIVED FROM HYDROPHOBIC POLYMERS AND METHODS OF PREPARING THE SAME - A composition of matter comprising a hydrophobic or hydrophilic (or both) interpenetrating polymer network containing a non-ionic/ionic polymer and a hydrophobic thermoset or thermoplastic polymer, articles made from such composition and methods of preparing such articles. The invention also includes a process for preparing a hydrophobic/hydrophilic IPN or semi-IPN from a hydrophobic thermoset or thermoplastic polymer including the steps of placing an non-ionizable/ionizable monomer solution in contact with a hydrophobic thermoset or thermoplastic polymer; diffusing the monomer solution into the hydrophobic thermoset or thermoplastic polymer; and polymerizing the monomers to form a penetrating polymer inside the hydrophobic thermoset or thermoplastic polymer, thereby forming the IPN or semi-IPN. | 2015-10-08 |
20150284655 | SILICONE LUBRICANT - A curing formulation operative as a lubricant is provided that has a plurality of silicone polymer precursors constituting a majority by weight of the formulation, each of the plurality of the silicone polymer precursors has a single curable moiety. A crosslinker is provided for reaction with the single curable moiety of each of the plurality of silicone polymer precursors to yield a thermoplastic silicone polymer having a majority by total weight of silicone polymer being comb- or branched-polymer form as the lubricant. A process of lubricating an interface is provide that includes the application of an aforementioned composition to the interface. Upon allowing sufficient time for the formulation to cure in ambient temperature conditions, a thermoplastic silicone polymer is formed having a majority by total weight of silicone polymer being comb- or branched-polymer. | 2015-10-08 |
20150284656 | VISCOSITY INDEX IMPROVER, METHOD FOR PRODUCING SAME, AND OIL COMPOSITION - The present invention provides a viscosity index improver that is excellent in an effect of improving a viscosity index and a high-temperature high-shear viscosity of oils, etc. The viscosity index improver of the present invention includes a hydrogenated product of a copolymer containing a constitutional unit (a) derived from an aromatic vinyl compound and a constitutional unit (b) derived from a conjugated diene, a content of a constitutional unit (b | 2015-10-08 |
20150284657 | Concentrated MetalWorking Fluid and MetalWorking Process - A concentrated metalworking fluid comprising from 60 to 90 percent by weight base oil selected from the group consisting of water soluble polyalkylene glycols, methoxypolyethylene glycols, polyethylene glycols, and combinations of two or more thereof; from 5 to 20 percent by weight glycol ether; from 0.01 to 5 percent by weight oil soluble polyalkylene glycol; and from 0.2 to 6 percent by weight one or more additives selected from the group consisting of anti-weld agents, corrosion inhibitors, extreme pressure additives, buffers, biocides, lubricity additives, and combinations of two or more thereof is provided. Further provided is a metalworking process. | 2015-10-08 |
20150284658 | ENZYMATIC DEGUMMING - The present invention relates to a method for treating vegetable oils and/or animal fats. The method comprises adjusting temperature, treatment with acid, adjusting pH, contacting the aqueous mixture with enzyme, crystallization of high melting glycerides and separation. | 2015-10-08 |
20150284659 | METHOD AND COMPOSITION FOR INCREASING RECOVERY OF OIL FROM FERMENTATION PROCESSES - The present invention relates to a method for increasing recovery of oil, such as vegetable oil, from a fermentation process. | 2015-10-08 |
20150284660 | METHOD TO IMPROVE THE PERFORMANCE OF ENCAPSULATED FRAGRANCES - The invention relates to a perfume composition that includes a first perfume microcapsule encapsulating a first perfume oil that has a Log T greater than −2.5 and a cLogP greater than 2.5 and/or a volatility value of at least 30 μg/l air; and a second perfume microcapsule encapsulating a second perfume oil ingredient that has a LogT less than −2.5 and a cLogP greater than 2.5 and/or a volatility value of at least 30 μg/l air. The invention also relates to the use of such mixtures of microcapsules as a perfuming ingredient or perfuming composition for home or personal care products, as well as to the resulting home and body care compositions. Also, a method for increasing shelf life of a home- or personal-care product that contains a perfuming composition which comprises providing the perfume composition as one of the mixtures of microcapsules disclosed herein. | 2015-10-08 |
20150284661 | Waxy Oxidation Products Of Rice Bran - The invention relates to waxy oxidation products of rice bran, which are characterized by an acid number measured according to DIN ISO 21 14 of at least 70 mg KOH/g, preferably at least 100 mg KOH/g, most preferably at least 140 mg KOH/g, and their use for producing synthetic ester waxes by esterification with one or more mono- or polyvalent alcohols. | 2015-10-08 |
20150284662 | LINEAR ALKYLBENZENES FROM NATURAL OILS AND METHODS OF PRODUCING - A linear alkyl benzene product and production of linear alkylbenzene from a natural oil are provided. A method comprises the step of deoxygenating the natural oils to form a stream comprising paraffins. The paraffins are dehydrogenated to provide mono-olefins. Then, benzene is alkylated with the mono-olefins under alkylation conditions to provide an alkylation effluent comprising alkylbenzenes and benzene. Thereafter, the alkylbenzenes are isolated to provide the alkylbenzene product. | 2015-10-08 |
20150284663 | NON-SILICATED HIGH ALKALINE CLEANER WITH ALUMINUM PROTECTION - Warewashing detergents suitable for dishwashing, immersion or dipping cleaning, and hard surface cleaning are disclosed for use on hard surfaces, including for example alkaline sensitive metals, such as aluminum or aluminum containing alloys. Alkaline compositions of a mixture of phosphono ethane carboxylates phosphono oligomers and methods employing the same are disclosed. The compositions eliminate the use of highly abrasive silicates, while retaining cleaning performance and corrosion prevention. The compositions according to the invention prevent the corrosive effect of highly alkaline compositions on aluminum or aluminum containing alloys. | 2015-10-08 |
20150284664 | Dishwashing Detergent Composition Comprising Soapwort Extract - The invention relates to a detergent composition that comprises a soapwort extract that is formulated to provide effective cleaning at low temperatures. | 2015-10-08 |
20150284665 | Capsules - Core-shell capsules comprising a fragrance-containing core and a shell formed around said core, wherein the shell is formed of polycarboxylic acid having a molecular weight of 1,000 to 10,000,000 Daltons | 2015-10-08 |
20150284666 | DEGREASING MIXTURE - The invention relates to a degreasing mixture for removing grease, oils, or similar hydrophobic components from a surface of a substrate. The degreasing mixture contains a solvent-free silicate mixture as the main component. The silicate mixture contains granules of phyllosilicate and granules of tectosilicate. Up to 90% by mass of the granules contained in the silicate mixture has a particle size of less than 60 μm, and the maximum particle size of the granules of phyllosilicate is smaller than the maximum particle size of the granules of tectosilicate. | 2015-10-08 |
20150284667 | ALCOHOLIC BEVERAGES WITH HEALTH-BENEFITTING AND PROTECTIVE CHARACTERISTICS - An alcoholic beverage and method for production thereof are provided. The alcoholic beverage includes ingredients that enhance the flavor and taste profile and the health-benefiting and protective characteristics of the alcoholic beverage. The alcoholic beverage may include at least one of L-theanine, resveratrol, and epigallocatechin in effective amounts. | 2015-10-08 |
20150284668 | Cyclic Microfluidic Chip and Method of Using the Same - The present invention related to a cyclic microfluidic chip that comprises a substrate and a top cover. The substrate having a surface that provides a chamber providing location of a first cell and having a first microchannel, a second microchannel being wrapped around the outside of the chamber and comprising an ECM inlet and an ECM outlet; and a third microchannel being wrapped around the outside of the second microchannel and comprising an cell inlet and an cell outlet to provide a second cell input and output respectively. The top cover comprises a fourth microchannel to provide a medium input and a medium output. | 2015-10-08 |
20150284669 | METHODS OF CULTURING CELLS OR TISSUES AND DEVICES FOR CELL OR TISSUE CULTURE - A method of culturing cells or tissues is provided. The method comprises a) providing a support, wherein the support is an optical medium with a patterned surface; b) contacting the support with cells and a culture medium; and c) culturing the cells under suitable cultivation conditions. A device for cell or tissue culture comprising an optical medium, wherein a patterned surface of the optical medium forms a support upon which cells are cultivated, is also provided. | 2015-10-08 |
20150284670 | Horizontal Plate Microbial Support Media - A horizontal plate microbial support media. The horizontal plate microbial support media having a plurality of frustum shaped protuberances extending there-from, the frustum shapes having a hole in their upper base for allowing fluid to flow there-through. These media plates able to be stacked for use in a bioreactor. | 2015-10-08 |
20150284671 | SINGLE USE CENTRIFUGE SYSTEM FOR HIGHLY CONCENTRATED AND/OR TURBID FEEDS - A method and apparatus for cell harvest of production scale quantities of cell cultures using single use components includes a flexible membrane mounted on a rigid frame and is supported within a multiple use rigid centrifuge bowl, such single use components including a core with an increased diameter and an internal truncated cone shape in order to permit the system to maintain a sufficiently high angular velocity to create a settling velocity suited to efficiently processing highly concentrated cell culture streams. Features which minimize feed turbidity, and others which permit the continuous or semi-continuous discharge of cell concentrate, increase the overall production rate over the rate which can be achieved using current intermittent processing methods for large cell culture volumes. Injection of a diluent during the cell concentrate removal process permits more complete removal of viscous cell concentrates. | 2015-10-08 |
20150284672 | SYSTEMS AND METHODS OF SEPARATING AND SINGULATING EMBRYOS - Separating and singulating embryos employs a spray module configured to spray a plurality of embryos which are loaded on a porous substrate so as to separate and singulate the plurality of embryos, and a drying module configured to dry the plurality of separated and singulated embryos retained on the porous substrate while the porous substrate is moved across the drying module. A robotic arm operates to transfer the porous substrate from module to module, and a control device controls the operation of the system of separating and singulating embryos. | 2015-10-08 |
20150284673 | HARVESTING ALGAE FROM WATER - The present application includes methods to harvest a non-vascular photosynthetic organism (NVPO) such as microalgae from an aqueous culture comprising brackish, non-brackish, marine, sea or saline water using polymer flocculants. The methods are suitable for harvesting NVPO from aqueous culture with total dissovled solids (TDS) of at least 1500 mg/L. Methods are also provided to harvest a NVPO using flocculation with or without a Dissolved Air Flotation (DAF) process. Methods are further provided to flocculate and harvest a NVPO directly in a pond. The present application further provides NVPO-containing intermediates, compositions, or products produced by the methods provided herein. | 2015-10-08 |
20150284674 | CAMPYLOBACTER BACTERIA AND DETECTION - There is provided a polynucleotide comprising a sequence at least 98.5% identical to SEQ ID NO: 1 and cells comprising this sequence, for example ECACC Deposit Reference 12022102. The polynucleotides and cells are useful in the detection of spotty liver syndrome and spotty liver disease. | 2015-10-08 |
20150284675 | STREPTOCOCCUS THERMOPHILUS STRAINS FOR TREATING HELICOBACTER PYLORI INFECTION - The present invention relates to a strain of | 2015-10-08 |
20150284676 | EXTRACTION OF NITROGEN FROM ORGANIC MATERIALS THROUGH AMMONIFICATION BY MIXED BACTERIAL POPULATIONS - The invention provides a process for producing ammonia or ammonium from an organic material by fermenting a medium comprising organic material in the presence of a mixed bacterial population capable of ammonification, wherein the fermenting is under conditions, and for a sufficient period of time, to produce a fermentation product that comprises ammonia or ammonium. The organic material includes nitrogenous compounds suitable for conversion to ammonia or ammonium. | 2015-10-08 |
20150284677 | Mycoplasma Hyopneumoniae Vaccine - This invention provides an immunogenic composition including a soluble portion of a | 2015-10-08 |
20150284678 | PCV/Mycoplasma Hyopneumoniae/PRRS Combination Vaccine - This invention provides a trivalent immunogenic composition including a soluble portion of a | 2015-10-08 |
20150284679 | USE OF STEM CELL CONDITIONED MEDIUM TO INHIBIT MELANIN FORMATION FOR SKIN WHITENING - A use of a stem cell conditioned medium to inhibit melanin formation for skin whitening is revealed. First, mesenchymal stem cells are cultured in a cell culture dish containing complete growth media. After mesenchymal stem cells are sub-cultured in a complete growth media for three times, a conditioned medium can be acquired from the basal media. | 2015-10-08 |
20150284680 | THIN FILMS FOR CONTROLLED CELL GROWTH - A method for controlling the attachment and growth of cells on a surface of an article, the method comprising contacting the article with living tissue, living organisms, or with water in an aqueous system comprising living organisms wherein the article comprises a substratum having a surface and a film on the surface, the film comprising a network of a net positively charged composition and a net negatively charged composition, wherein the net positively charged composition comprises a net positively charged polyelectrolyte or the net negatively charged composition comprises a net negatively charged polyelectrolyte, and the net positively charged polyelectrolyte or the net negatively charged polyelectrolyte contain (i) a polymer repeat unit having at least two fluorine atoms, or (ii) a polymer repeat unit having a zwitterion group. | 2015-10-08 |
20150284681 | Direct Conversion of Cells to Cells of Other Lineages - Methods, compositions and kits for producing functional neurons, astroctyes, oligodendrocytes and progenitor cells thereof are provided. These methods, compositions and kits find use in producing neurons, astrocytes, oligodendrocytes, and progenitor cells thereof for transplantation, for experimental evaluation, as a source of lineage- and cell-specific products, and the like, for example for use in treating human disorders of the CNS. Also provided are methods, compositions and kits for screening candidate agents for activity in converting cells into neuronal cells, astrocytes, oligodendrocytes, and progenitor cells thereof. | 2015-10-08 |
20150284682 | BLOOD STORAGE BAG SYSTEM AND DEPLETION DEVICES WITH OXYGEN AND CARBON DIOXIDE DEPLETION CAPABILITIES - A blood storage system. The system has a collection bag for red blood cells; an oxygen/carbon dioxide depletion device; a storage bag for red blood cells; and tubing connecting the collection bag to the depletion device and the depletion device to the storage bag. The depletion device includes a receptacle of a solid material having an inlet and an outlet adapted to receiving and expelling a flushing gas; a plurality of hollow fibers or gas-permeable films extending within the receptacle from an entrance to an exit thereof. The hollow fibers or gas-permeable films are adapted to receiving and conveying red blood cells. | 2015-10-08 |
20150284683 | METHOD, COMBINATION AND/OR COMPOSITION FOR INDUCING CARDIOMYOCYTE DIFFERENTATION - The present invention relates to a method for inducing cardiomyocyte differentiation using a combination and/or composition of factors. The present invention also includes the combination and/or composition of factors. For example, the factors comprise at least one p38-MAPK modulator, at least one immunomodulator, at least one Wnt modulator and/or at least one ROS modulator. In particular, the factors comprise at least one p38-MAPK inhibitor, at least one immunosuppressant, at least one Wnt modulator and/or at least one ROS activator. | 2015-10-08 |
20150284684 | DIFFERENTIATION OF PRIMATE PLURIPOTENT STEM CELLS TO CARDIOMYOCYTE-LINEAGE CELLS - The present application describes the new methods for the differentiation of primate pluripotent stem cells into cardiomyocyte-lineage cells. The methods utilize sequential culturing of the primate pluripotent stem cells in certain growth factors to produce cardiomyocyte-lineage cells. In certain embodiments of the invention, the population of cells produced by the sequential culturing is further enriched for cardiomyocyte-lineage cells so as to produce a higher percentage of those cells. | 2015-10-08 |
20150284685 | DEVICE AND METHOD FOR OPENING EXTRACTED TEETH AND REMOVAL OF PULP - A tooth cracking device improves the efficiency of removal of pulp from extracted teeth. The device may have:
| 2015-10-08 |
20150284686 | Method for Culturing Mesenchymal Stem Cells - Disclosed is a method for culturing mesenchymal stem cells, comprising culturing mesenchymal stem cells in a medium containing calcium in a concentration of from 2.1 to 3.8 mM and magnesium in a concentration of from 1.0 to 3.0 mM under a hypoxic condition of 2 to 5% oxygen. The culturing method can increase the population of mesenchymal stem cells even with a small number of passages by improving mesenchymal stem cells in proliferative capacity and viability. In addition, the mesenchymal stem cells prepared by the culturing method are effectively used not only as a safe cell therapeutic agent due to their lacking immunogenicity, but also as a cartilage regenerating medicine owing to their excellent secretion of cytokines. | 2015-10-08 |
20150284687 | CELL THERAPY: A METHOD AND A COMPOSITION FOR TREATING DIABETES - A method of obtaining beta-islet cells from pancreases of rabbits and a composition for transplantation (xenografts or xenotransplants) of beta-islet cells isolated and cultured from rabbit pancreases to promote natural insulin production among people with diabetes. | 2015-10-08 |
20150284688 | DIFFUSIBLE FACTORS AND CANCER CELLS - The present invention relates to modified cancer cells that are defective in the production of diffusible factors (e.g., growth factors), and to the use of such cells for impairing the growth of a population of human cells, in particular wherein the cells are human cancer cells and the population of cells is a neoplasm, tumour or cancer. The invention preferably comprises the step of modifying tumour cells by deleting or modifying endogenous genes that code for (or affect the production of), diffusible growth factors that promote cell survival and proliferation. | 2015-10-08 |
20150284689 | STRATEGY FOR ENGINEERING VARIOUS 3D TISSUES, ORGANOIDS AND VASCULATURE - Provided are methods and compositions for constructing stable mammalian epithelial and/or endothelial tissues and organs. Disclosed are methods of using active epithelial and/or endothelial growth factors having the capability of effectuating induction of growth and morphogenesis of cells. | 2015-10-08 |
20150284690 | HEPATITIS B VIRUS MUTANT, MUTANT AMPLIFICATION KIT AND USE THEREOF - The present invention relates to the field of biotechnology, and discloses a hepatitis B virus mutant, a mutant amplification kit and use thereof. The HBV mutant of the invention takes place mutation of the hepatitis B virus mutant in genome sequence No. 216 and/or 285, the mutation occurred at position 216 is that base T mutates to C, the mutation occurred at position 285 is that base G mutates to A. The two mutations are closely related to the inflammation aggravation of the hepatitis B. The invention further provides a HBV mutant amplification kit to detect the above mutation, the usage of the kit and its application, therefore offering help for the clinical early diagnosis and intervention of severe hepatitis B, and providing references for further studying the functional changes caused by HBV gene mutation. | 2015-10-08 |
20150284691 | COMPOSITION OF VIRAL VECTORS IN LECITHIN LIPOSOMES, PREPARATION METHOD AND TREATMENT METHODS - A composition is provided which comprises a recombinant viral particle comprising a capsid, wherein the viral particle is encapsulated into an anionic liposome comprising lecithin and polyethylene glycol (PEG). A method for preparing and purifying the encapsulated viral particles is provided as well. Methods for treating patients by using the encapsulated viral particles are provided as well. | 2015-10-08 |
20150284692 | RECOMBINANT MICROORGANISMS AND USES THEREFOR - The invention provides, inter alia, methods for the production of acetone, isopropanol and/or precursors of acetone and/or isopropanol by microbial fermentation of substrates comprising CO, genetically modified microorganisms of use in such methods, nucleic acids suitable for preparation of genetically modified microorganisms, a novel alcohol dehydrogenase and nucleic acids encoding same. | 2015-10-08 |
20150284693 | PROTEIN COMPLEX CAPABLE OF CATALYZING ASYMMETRIC OXIDATION REACTION AND METHOD FOR PRODUCING SAME - Provided are: a protein complex capable of selectively and asymmetrically oxidizing an enantiomer of a secondary alcohol without adding a coenzyme and having an asymmetric oxidation activity in a water-soluble solvent system in the presence of oxygen; a method for producing the same; and a method for coating the protein complex with a high molecular weight compound. The method for producing the protein complex includes: (1) enclosing a crude water-soluble protein in a gel, air-oxidizing the gel, and eluting the protein complex into an aqueous solution; and (2) applying gravity to concentrate and precipitate the protein complex, redissolving the precipitate in an aqueous glycine sodium hydroxide solution of about 0.5 mM and allowing the same to homogeneously coexist with a high molecular weight compound, and re-precipitating the solution and dehydrating and drying the same to yield a protein complex coated with a high molecular weight compound. | 2015-10-08 |
20150284694 | ALDEHYDE DEHYDROGENASE MUTANT, POLYNUCLEOTIDE ENCODING THE MUTANT, VECTOR AND MICROORGANISM HAVING THE POLYNUCLEOTIDE, AND METHOD OF PRODUCING 1,4-BUTANEDIOL BY USING THE SAME - An aldehyde dehydrogenase mutant polypeptide, a recombinant microorganism including a polynucleotide encoding the polypeptide, and a method of producing 1,4-butanediol by using the same. | 2015-10-08 |
20150284695 | Recombinase Polymerase Amplification - This disclosure describes related novel methods for Recombinase-Polymerase Amplification (RPA) of a target DNA that exploit the properties of recombinase and related proteins, to invade double-stranded DNA with single stranded homologous DNA permitting sequence specific priming of DNA polymerase reactions. The disclosed methods have the advantage of not requiring thermocycling or thermophilic enzymes, thus offering easy and affordable implementation and portability relative to other amplification methods. Further disclosed are conditions to enable real-time monitoring of RPA reactions, methods to regulate RPA reactions using light and otherwise, methods to determine the nature of amplified species without a need for gel electrophoresis, methods to improve and optimize signal to noise ratios in RPA reactions, methods to optimize oligonucleotide primer function, methods to control carry-over contamination, and methods to employ sequence-specific third ‘specificity’ probes. Further described are novel properties and approaches for use of probes monitored by light in dynamic recombination environments. | 2015-10-08 |
20150284696 | DNA POLYMERASES WITH IMPROVED ACTIVITY - Disclosed are DNA polymerases having increased reverse transcriptase efficiency relative to a corresponding, unmodified polymerase. The polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the DNA polymerases. | 2015-10-08 |
20150284697 | ENDORIBONUCLEASE COMPOSITIONS AND METHODS OF USE THEREOF - The present disclosure provides variant Csy4 endoribonucleases, nucleic acids encoding the variant Csy4 endoribonucleases, and host cells genetically modified with the nucleic acids. The variant Csy4 endoribonucleases find use in a variety of applications, which are also provided. The present disclosure also provides methods of detecting a specific sequence in a target polyribonucleotide; and methods of regulating production of a target RNA in a eukaryotic cell. | 2015-10-08 |
20150284698 | PURIFICATION OF RECOMBINANT HUMAN GALACTOCEREBROSIDE B-GALACTOSIDASE (rhGALC) - The present invention relates to a process for purifying recombinant human Galactocerebroside β-Galactosidase dase (rhGALC) from a cell culture, wherein a fraction of said cell culture comprising rhGALC is subjected to chromatography on three distinct resins. | 2015-10-08 |
20150284699 | NOVEL XYLANASE - The purpose of the present invention is to provide a novel xylanase having various excellent enzymological properties, and that is suitable for industrial applications. The polypeptide is selected from the group consisting of (a), (b), and (c) below: (a) a polypeptide comprising an amino acid sequence selected from SEQ ID NOs: 1 to 7; (b) a polypeptide having xylanase activity and comprising an amino acid sequence selected from SEQ ID NOs: 1 to 7, the amino acid sequence having substitution, deletion, insertion, and/or addition of one or several amino acid residues; and (c) a polypeptide having xylanase activity and comprising an amino acid sequence having at least 80% identity with an amino acid sequence selected from SEQ ID NOs. 1 to 7. | 2015-10-08 |
20150284700 | BGL7 Beta-Glucosidase and Nucleic Acids Encoding the Same - The present invention provides a novel β-glucosidase nucleic acid sequence, designated bgl7, and the corresponding BGL7 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL7, recombinant BGL7 proteins and methods for producing the same. | 2015-10-08 |
20150284701 | FUSION PROTEINS OF COLLAGEN-BINDING DOMAIN AND PARATHYROID HORMONE - Fusion proteins containing active agonist or antagonist fragments of parathyroid hormone (PTH) and parathyroid hormone related peptide (PTHrP) coupled to a collagen-binding domain are presented. The fusion proteins can be used to promote bone growth, to promote hair growth, to prevent cancer metastasis to bone, to promote immune reconstitution with a bone marrow stem cell transplant, to promote mobilization of bone marrow stem cells for collection for autologous stem cell transplant, and to treat renal osteodystrophy. Pharmaceutical agents comprising a collagen-binding polypeptide segment linked to a non-peptidyl PTH/PTHrP receptor agonist or antagonist are also presented. | 2015-10-08 |
20150284702 | METHOD FOR THE DETERMINATION OF BOTULINUM NEUROTOXIN BIOLOGICAL ACTIVITY - The present invention relates to means and methods for determining neurotoxin activity. Specifically, it relates to a polypeptide having caspase activity comprising a large subunit and a small subunit wherein the caspase further comprises a neurotoxin cleavage site which upon cleavage activates the caspase activity. Also encompassed are polynucleotides encoding the polypeptides as well as vectors or host cells comprising the polynucleotides. The present invention further relates to a method for determining neurotoxin activity in a sample based on the polypeptide of the invention as well as the use of the polypeptide for determining neurotoxin activity in a sample, in general. | 2015-10-08 |
20150284703 | Thermally Stable Enzymes, Compositions Thereof and Methods of Using Same - Described herein are proteins having lyase activity and nucleic acid sequences which code therefor; along with methods of expressing, isolating, purifying, and using same. | 2015-10-08 |
20150284704 | INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF CYSTEINYL-TRNA SYNTHETASE - Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications. | 2015-10-08 |
20150284705 | INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF METHIONYL-TRNA SYNTHETASIS - Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications. | 2015-10-08 |
20150284706 | INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF THREONYL-TRNA SYNTHETASES - Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications. | 2015-10-08 |
20150284707 | APPARATUS AND METHOD FOR NUCLEIC ACID SEQUENCING BASED ON NANOCHANNELS - An apparatus for nucleic acid sequencing includes a nanochannel and a conveying device, configured to move a nucleic acid strand through the nanochannel. The conveying device includes: a first electrode, a second electrode, and a third electrode, which are arranged along the nanochannel so as to be in contact with a fluid occupying the nanochannel, the second electrode being arranged between the first electrode and the third electrode; and a control unit configured to apply a first voltage, a second voltage, and a third voltage, respectively, to the first electrode, the second electrode and the third electrode, for controlling movement of the nucleic acid strand through the nanochannel. | 2015-10-08 |
20150284708 | Oligonucleotide Complex Compositions - Compositions and methods of treatments of cells are provided for altering the phenotype of a cell by administering an oligonucleotide complex to the cell, the complex having two strands and chemical modifications. | 2015-10-08 |
20150284709 | SYSTEM AND METHOD FOR PROCESSING PARAFFIN EMBEDDED SAMPLES - Method and apparatus for processing paraffin embedded samples, e.g., to disassociate paraffin from tissue components and/or other biomolecules from the paraffin. The sample may be exposed to focused acoustic energy while held in a vessel containing a non-solvent, aqueous solution. Disassociated paraffin may be emulsified into the liquid or otherwise separated from the sample. | 2015-10-08 |
20150284710 | METHOD OF MANIPULATING SOLID CARRIERS AND AN APPARATUS OF MANIPULATING SOLID CARRIERS - The present invention provides a method of manipulating a solid carrier and an apparatus of manipulating a solid carrier in which the solid carrier is passed through more regions in liquid in a vessel. More specifically, the method of manipulating the solid carrier is a method of manipulating a solid carrier in a liquid contained in a vessel, the solid carrier being magnetic and capable of carrying a substance, the method comprising: manipulating the solid carrier using a magnetic force application unit adapted to applying a magnetic force to the solid carrier in the vessel so that the relative position between the magnetic force application unit and the vessel is altered over a period of time by means of directing the solid carrier in a direction along either one or a combination of the vectors of the longitudinal direction of the vessel and the direction crossing the longitudinal direction of the vessel. | 2015-10-08 |
20150284711 | USE OF A REWIRED GENETIC CONTROL NETWORK TO INCREASE PRODUCT EXPRESSION - A method of identifying a cell with increased production of a desired product, the method comprising: (a) providing a population of cells which produce the desired product; (b) introducing a plurality of distinct nucleic acid molecule species into the population of cells, wherein the nucleic acid molecules comprise a first region which is operably-linked to a second region, wherein the first region comprises a promoter region from a first gene, and the second region comprises a nucleic acid sequence from a second gene that is capable of expressing a regulatory product under control of the promoter region; (c) culturing the population of cells under conditions in which the cells express the regulatory product under control of the promoter region; and (d) testing the population of cells for production of the desired product, thereby to identify a cell or cells with increased production of the desired product. The method may further comprise isolating a cell or cells with increased production of the desired product. The method may further comprise repeating steps (b), (c) and (d) on the isolated cells or cells, or descendants thereof with increased production of the desired product, thereby to identify a cell or cells with further increased production of the desired product. Typically the desired product is not encoded by the introduced nucleic acid molecule. The plurality of distinct nucleic acid molecule species typically comprise a plurality of combinations of multiple first and multiple second regions. The expressed regulatory product typically is a polypeptide but may be an RNA molecule. The method may further comprise isolating the nucleic acid molecule(s) introduced into the cell or cells with increased production of the desired product. | 2015-10-08 |
20150284712 | BARCODING NUCLEIC ACIDS - Methods of barcoding nucleic acids, such as genomic DNA, are provided herein. In some embodiments, a fragment of genomic DNA may comprise a first and a second barcode. | 2015-10-08 |
20150284713 | RECOGNITION TAGS FOR TGASE-MEDIATED CONJUGATION - The present application relates to methods for the functionalization of antibodies using transglutaminase, in particular antibodies lacking Fc regions. Also disclosed herein are peptide tags for transglutaminase, linking reagents, functionalized antibodies, multi-specific antibodies, pharmaceutical compositions, and method of treating disease and/or conditions. | 2015-10-08 |
20150284714 | SAMPLE PREPARATION ON A SOLID SUPPORT - Presented are methods and compositions for using immobilized transposase and a transposon end for generating an immobilized library of 5′-tagged double-stranded target DNA on a surface. The methods are useful for generating 5′- and 3′-tagged DNA fragments for use in a variety of processes, including massively parallel DNA sequencing. | 2015-10-08 |
20150284715 | Enrichment Methods - Methods are described for the separation of microspheres covered with nucleic acids of interest from undesired microspheres and/or molecules. These separations may be negatively affected by the presence of non-specific interactions between nucleic acids or microspheres. | 2015-10-08 |
20150284716 | METHOD FOR SINGLE CELL SEQUENCING OF MIRNAS AND OTHER CELLULAR RNAS - Provided herein are methods for single cell sequencing of miRNAs and other low abundance and/or or short cellular RNAs. | 2015-10-08 |
20150284717 | OLIGOMERS WITH CONFORMATIONALLY RESTRICTED MONOMERS AND UNLOCKED NUCLEOMONOMERS - This invention provides single-stranded and multi-stranded compounds that are useful in various therapeutic modalities to regulate the expression of nucleic acid molecules in a cell. A range of compounds is provided, each containing one or more conformationally restricted nucleomonomers (CRN). In addition, compounds can contain one or more conformationally restricted nucleomonomers and one or more hydroxymethyl substituted nucleomonomers (unlocked nucleomonomers, UNA). | 2015-10-08 |
20150284718 | miRNA169 COMPOSITIONS AND METHODS FOR THE REGULATION OF CARBOHYDRATE METABOLISM AND FLOWERING IN PLANTS - Compositions and methods for modulating flowering, sugar metabolism and stress response in plants are provided. | 2015-10-08 |
20150284719 | METHODS AND COMPOSITIONS INVOLVING MIRNA AND MIRNA INHIBITOR MOLECULES - The present invention concerns methods and compositions for introducing miRNA activity or function into cells using synthetic nucleic acid molecules. Moreover, the present invention concerns methods and compositions for identifying miRNAs with specific cellular functions that are relevant to therapeutic, diagnostic, and prognostic applications wherein synthetic miRNAs and/or miRNA inhibitors are used in library screening assays. | 2015-10-08 |
20150284720 | METHODS AND COMPOSITIONS INVOLVING MIRNA AND MIRNA INHIBITOR MOLECULES - The present invention concerns methods and compositions for introducing miRNA activity or function into cells using synthetic nucleic acid molecules. Moreover, the present invention concerns methods and compositions for identifying miRNAs with specific cellular functions that are relevant to therapeutic, diagnostic, and prognostic applications wherein synthetic miRNAs and/or miRNA inhibitors are used in library screening assays. | 2015-10-08 |
20150284721 | ORGANIC COMPOSITIONS TO TREAT HSF1-RELATED DISEASES - The present disclosure relates to methods of treating heat shock factor 1 (HSF1)-related diseases such as cancer and viral diseases, using a therapeutically effective amount of a RNAi agent to HSF. | 2015-10-08 |
20150284722 | METHODS AND COMPOSITIONS FOR USE IN TREATMENT OF FOXP2-RELATED CANCERS - The present invention relates, in part, to the treatment and prevention of cancers by administering agents that modulate the activity or expression of microRNAs. | 2015-10-08 |
20150284723 | PME-1 AS A BIOMARKER TO PREDICT AND DIAGNOSE ENDOMETRIAL AND BREAST CANCER AND GENE SILENCING OF PME-1 TO INHIBIT EPITHELIAL TO MESENCHYMAL TRANSITION - Disclosed are methods of attenuating activity of the PME-1 gene. siRNAs or shRNAs are used to target against PME-1, thereby reducing the PME-1 mRNA. It is disclosed that the siRNAs or shRNAs targeted against PME-1 attenuate the epithelial to mesenchymal transition, thereby inhibit endometrial cancer and triple negative breast cancer development. A kit containing siRNA or shRNA reagents for attenuating the PME-1 gene expression is also disclosed. | 2015-10-08 |
20150284724 | TREATMENT OF SIRTUIN (SIRT) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO A SIRTUIN (SIRT) - The present invention relates to antisense oligonucleotide that modulate the expression of and/or function of a Sirtuin (SIRT), in particular, by targeting natural antisense polynucleotides of a Sirtuin (SIRT). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of Sirtuins (SIRT)s. | 2015-10-08 |
20150284725 | METHODS OF TREATING KENNEDY'S DISEASE - Certain embodiments are directed to methods of ameliorating, treating, or preventing Kennedy's Disease in a subject carrying a mutation in the Androgen Receptor (AR) gene, such as expansion of a CAG trinucleotide repeat, which is associated with Kennedy's Disease, by administering an antisense compound targeted to AR. Several embodiments provided herein relate to the discovery that antisense compounds targeting Androgen Receptor can ameliorate, treat, or prevent Kennedy's Disease in a subject carrying a mutation in the Androgen Receptor gene, such as expansion of a CAG trinucleotide repeat, which is associated with Kennedy's Disease. | 2015-10-08 |
20150284726 | RNAi Inhibition of A1pha-ENaC Expression - The invention relates to compositions and methods for modulating the expression of alpha-ENaC, and more particularly to the downregulation of alpha-ENaC expression by chemically modified oligonucleotides. | 2015-10-08 |