39th week of 2014 patent applcation highlights part 42 |
Patent application number | Title | Published |
20140287377 | GUIDED DENTAL IMPLANTATION SYSTEM AND ASSOCIATED DEVICE AND METHOD - A dental implantation system is provided, comprising an implantation device adapted to prepare a site within a mouth of a patient for receiving a dental implant. A guidance device is operably engaged with the implantation device and is adapted to operably engage the mouth of the patient. The engagement between the guidance device and the mouth of the patient provides a fiducial marker for guiding the implantation device to prepare the site for receiving the dental implant. An associated method of implanting a dental implant, and associated devices, are also provided. | 2014-09-25 |
20140287378 | DENTAL CURING LIGHTS AND RELATED METHODS - Embodiments of the present invention include dental curing lights comprising a battery, and a fire resistant mesh bag at least partially enclosing the battery therein. Additionally, the battery and fire resistant mesh bag may be located within the dental curing light. Additional embodiments of the present invention include methods of manufacturing a dental curing lights. The methods may comprise enclosing a battery within a fire resistant mesh bag, and positioning the battery and fire resistant mesh bag into the dental curing light. | 2014-09-25 |
20140287379 | Determination Of A Three Dimensional Relation Between Upper and Lower Jaws With Reference To A Temporomandibular Joint - An apparatus including a bite frame and a bite shaped member is provided. The bite frame includes one or more arcuate frame elements defining an opening for accommodating a mesh element or the bite shaped member that receives a bite registration material for registering a bite impression. The bite shaped member has a geometrical body structure, upper and lower channels of configurable shapes, and upper and lower windows. The upper and lower windows are separated by a space for receiving and allowing flow of the bite registration material to register a vertical distance between the upper and lower jaws. An image processing system operably connected to the apparatus determines the three-dimensional relation between the upper and lower jaws with reference to temporomandibular joints using panoramic images of the upper and lower jaws, reference points provided by radio-opaque markers, three-dimensional scanned images of the bite impression, and three-dimensional head surface images. | 2014-09-25 |
20140287380 | ORAL CARE GELS - The invention provides an orally acceptable plaque indicator gel comprising a dye in sufficient concentration to visibly stain plaque upon application, optionally for use in combination with an orally acceptable plaque removal gel comprising an antiplaque agent in sufficient concentration to remove plaque and or kill bacteria upon application, in each case the gel having a specific viscosity permitting efficient application using a pen dispenser, as well as reduced dye or antiplaque agent concentration, together with methods of using the same. | 2014-09-25 |
20140287381 | System, Method and Apparatus for Adaptive Driver Training - An application for an adaptive training system includes a computer interfaced to one or more graphics displays, one of more input/output devices and having access to a plurality of training segments. The input/output devices are in communication with a trainee. Software operates in either a simulation mode in which a trainee interacts with the adaptive training system as if the trainee was operating a target vehicle or in a training mode in which the trainee receives computer-based training from the adaptive training system, in particular, when the trainee does not perform well during the simulation mode of operation. | 2014-09-25 |
20140287382 | Writing, Braille and Drawings Board for Blind or Visually Impaired Persons - The invention relates to a board for blind persons, which makes it easier to write, draw and learn shapes through positive relief elements that can be reused. When writing or drawing, it is possible to check what has been done and to correct errors detected with the fingertip ( | 2014-09-25 |
20140287383 | Scoring Server - A scoring server for assessing technical skills in a practical environment. A client application acts as a middle man between a terminal and an operating system to capture and forward all input from and output to students to the scoring server. The scoring server compares recorded student activity against a list of tasks deemed capable of accomplishing course objectives assigned to students. As objectives are met by a student, the students' grade is updated in real-time. Each student passes or fails an exam based on tasks performed and skills employed. The client application exists for two operating system types: windows and LINUX. A LINUX client employs a pseudoterminal to permit access to terminal input/output and communication through stdin, stdout, and stderr channels. A windows client (WC) comprises a WC command line activity logger and a WC monitor process to intercept all communication through stdin, stdout, and stderr communication channels. | 2014-09-25 |
20140287384 | Method, system and apparatus for improved nutritional analysis - A system having an incorporated software program attempts to tailor a person's diet with the person's desired nutritional goal and their current food consumption. The system provides food exchange lists to assist a person making food choices from a category of food. | 2014-09-25 |
20140287385 | Enunciation Device - This invention relates an enunciation device comprising a hollow device shaped in a manner to fit a mouth. This enunciation device assists with improving enunciation, slowing speech, and strengthens mouth, tongue, and jaw muscles so that a user can build confidence while speaking. | 2014-09-25 |
20140287386 | Method and Apparatus for Teaching and Cognitive Enhancement - The present invention is a teaching and learning tool built on the principle that the human sense of touch makes a significant contribution in the visualization of objects. Sighted individuals can produce visual images inside the brain (commonly referred to as the “mind's eye”) via the sense of touch, where we use our minds, rather than our eyes, to visualize concrete objects allowing us to “get a picture” of that object. A “brain-sight” apparatus is disclosed that provides a box for containing object manipulatives and/or math manipulatives, two openings for receiving hands of a user, which openings are covered by a veil such that the user cannot see into the box. A user who places his hands into the box and manipulates the object manipulatives and/or math manipulatives in response to a posed problem, and then solves the posed problem in a traditional manner, benefits from cognitive enhancement provided by multi-modal stimulation of the somatosensory cortex and lateral occipital cortex. | 2014-09-25 |
20140287387 | EMOTION RECOGNITION SYSTEM AND METHOD FOR ASSESSING, MONITORING, PREDICTING AND BROADCASTING A USER'S EMOTIVE STATE - Systems and methods are provided for assessing, monitoring and predicting a person's emotive state based on the person's day-to-day social and physical activity, including biometric, geospatial and other data, and storing the emotive state in a form that can be used by others to enhance interaction with the person. Such interaction may be in the form of downloadable application, such as a video game, in which the play interaction is altered based upon the detected emotive state of the player. | 2014-09-25 |
20140287388 | Interactive Tumble Gymnastics Training System - A system for training and reviewing gymnast skills. A student performs a sequence of gymnastic maneuvers in front of a screen and a motion-capturing camera. The sequence of movements are captured by the camera and analyzed. The captured movements are projected alongside an animated silhouette character performing the defined movements of the gymnastic maneuver in sequence. Each captured movement of the student is compared to each animated silhouette character image for aligning the movements of the student to the defined movements of the animated silhouette character | 2014-09-25 |
20140287389 | SYSTEMS AND METHODS FOR REAL-TIME ADAPTIVE THERAPY AND REHABILITATION - Virtual reality-based adaptive systems and methods are disclosed for improving the delivery of physical therapy and rehabilitation. The invention comprises an interactive software solution for tracking, monitoring and logging user performance wherever sensor capability is present. To provide therapists with the ability to observe and analyze different motion characteristics from the exercises performed by patients, novel visualization techniques are provided for specific solutions. These visualization techniques include color-coded therapist-customized visualization features for motion analysis. | 2014-09-25 |
20140287390 | Training Device - This invention relates to a device for controlling of movement of limbs of a user in a substantially mirror symmetrical manner, a user's limb or limbs being held in position via support arms, said device comprising a bar (or bars) adapted to move about a point of rotation, said bar (or bars) having a first end and a second end, said ends separated by the point of rotation, a first support arm(s) operatively coupled at or towards one end of said bar and a second support arm(s) operatively coupled at or towards a different end of the bar wherein the first and second support arms are adapted to substantially support and/or hold the limbs of a user of said device, the first and second support arms and the bar (or bars) configured such that, in use, as the bar (or bars) rotate(s) the support arms move in a substantially tandem synchronised manner with respect to each other. | 2014-09-25 |
20140287391 | METHOD AND SYSTEM FOR TRAINING ATHLETES - A method and system is provided for training athletes using films or videotapes of game situations so that a player's reaction can be applied to such situations. The videos are taken from the player's eye-level perspectives on the field or court. The method and system can be used for various sports, including basketball, football, baseball, hockey, soccer, volleyball, wrestling, and any other sport, particularly team sports. Using this system and method of the present invention will enhance and expedite training of athletes. | 2014-09-25 |
20140287392 | BOARD GAME INSTRUMENT FOR LEARNING - Provided is a board game instrument for learning. The board game instrument includes at least two projectiles, a launch pad, at least two baskets, a game board, and at least two magic cards. The projectiles are thrown in a basket using a launch pad. The launch pad launches the projectile using an elastic force. The baskets are formed to be concave so as to hold the projectile launched from the launch pad and have a rim of a top surface and a bottom surface thereof formed to be flat. The game board includes an area in which the baskets are placed, and is configured such that at least three baskets acquired in a game are stacked up into a pyramid of two or more tiers on the area. | 2014-09-25 |
20140287393 | SYSTEM AND METHOD FOR THE EVALUATION OF OR IMPROVEMENT OF MINIMALLY INVASIVE SURGERY SKILLS - A system to assist in at least one of the evaluation of or the improvement of skills to perform minimally invasive surgery includes a minimally invasive surgical system, a video system arranged to record at least one of a user's interaction with the minimally invasive surgical system or tasks performed with the minimally invasive surgical system, and a data storage and processing system in communication with the minimally invasive surgical system and in communication with the video system. The minimally invasive surgical system provides at least one of motion data, ergonomics adjustment data, electrical interface interaction data or mechanical interface interaction data of at least a component of the minimally invasive surgical system in conjunction with time registered video signals from the video system. The data storage and processing system processes the at least one of motion data, ergonomics adjustment data, electrical interface interaction data or mechanical interface interaction data to provide a performance metric in conjunction with the time registered video signals to be made available to an expert for evaluation. | 2014-09-25 |
20140287394 | SYSTEM, METHOD, AND APPARATUS FOR ASSISTING IN THE DEVELOPMENT OF GOOD ORAL HYGIENE HABITS AMONG YOUNG CHILDREN - Brushing systems include a base configured to assist in keeping the system in an upright position. The base is coupled to a stand being sized, shaped, and positioned so as to couple the base and a support structure. The support structure is configured to provide support for a audio/video device positioned thereon, the audio/video device being configured to provide an audio/visual presentation to a child while brushing his or her teeth, the audio/visual presentation including information on proper oral hygiene habits. | 2014-09-25 |
20140287395 | METHOD AND SYSTEM FOR MEDICAL SKILLS TRAINING - A method for medical skills training is provided that includes simulating a current condition of at least one simulated patient wherein the current condition comprises dynamic physiology, appearance, and behavior of the patient using one or more physiology models; outputting the simulated patient in the current condition on a visual display; receiving input from one or more users, wherein the input represents one or more medical interactions to be virtually applied to the simulated patient; processing the inputs using the physiology model in conjunction with one or more physiological variables that change over time based on the physiology model, in response to corresponding deterioration clocks and the inputs; and outputting one or more changes to the current condition of the simulated patient by applying different animations to the simulated patient based on the processed inputs. As system and computer readable media for medical skills training are also provided. | 2014-09-25 |
20140287396 | SYSTEM, METHOD AND APPARATUS FOR CONSOLIDATING AND SEARCHING EDUCATIONAL OPPORTUNITIES - An application for a method and system providing educational seekers a search tool that finds education opportunities across a large number of educational/training providers. The search tool finds courses and/or programs of interest such as certifications, vocational programs, two-year programs, four-year programs, MBA programs, certain financial aide features, specific course offerings, specific sports programs, placement success, etc, The system includes educational software robots called edu bots that visit educational program hosting web sites of the various educational/training providers, extracting information regarding the programs, courses, faculty, financial assistance, sports programs, location, extra-curricular activities, etc. The information is then stored in a common, searchable database for later searching by the educational seeker. | 2014-09-25 |
20140287397 | SYSTEMS AND METHODS FOR CUSTOMIZED LESSON CREATION AND APPLICATION - A computer-implemented method according to various aspects of the present disclosure includes: retrieving, by a computer system, a lesson module from a database; receiving, by the computer system, information regarding a student; modifying the lesson module, by the computer system, based on the information regarding the student; and providing the lesson module to the student. | 2014-09-25 |
20140287398 | Computer Implemented System and Method for Statistically Assessing Co-Scholastic Skills of a User - A system and method for assessing the co-scholastic skills of users have been disclosed. The system envisaged by the present disclosure envisages screening speechless short films to individuals in order to assess their strengths and weaknesses in co scholastic areas such as attitude towards life, moral values, critical thinking skills, creative thinking skills, decision making skills, analytical skills; problem solving skills, communication skills and emotional sensitivity. The system exploits various ideas, concepts and messages imparted by the short speechless movies to enhance the co-scholastic skills of individuals. The user is required to view the short speechless film displayed on a user interface. Subsequent to viewing the short speechless film, the user is required to answer an assessment test, preferably online assessment test. Based on the answers of users to the displayed assessment questions, the user's competency in co-scholastic skills is determined by an assessment processor. | 2014-09-25 |
20140287399 | SYSTEMS AND METHODS FOR LEARNING AND LEARNING ORIENTED ASSESSMENT - The technique relates to a system and method for learning and learning oriented assessment of at least one learner based on a role to be performed by the at least one learner. This technique involves identifying knowledge areas related to a particular role to be performed by the learner. Under each knowledge area different learning workflows are identified and relevant topics are mapped to the learning workflows. The performance expectation from the learner at each learning workflow level is defined. The one more challenges related to the mapped topics are created and presented to the learner to solve and a score is generated for solving the challenges. This score is compared with the predefined performance expectation to determine the learning effectiveness of the learner and a capability index is computed for the learner. | 2014-09-25 |
20140287400 | OBJECT-BASED SYSTEM AND LANGUAGE FOR DYNAMIC DATA OR NETWORK INTERACTION INCLUDING LEARNING MANAGEMENT - A system including an object-oriented programming language for building state-based applications with flow control, event loops, measures of similarity, and Boolean logic to dynamically control the interaction between members in a social network around content and, in particular, project-based activities, where the system collects and groups individuals who are members of a social network, projects or assignments and their content, and activities or processes within projects based on the attributes of the objects and runtime events to create a social context for learning or for other interaction. | 2014-09-25 |
20140287401 | MODEL - The present disclosure is directed to model figures of beings or objects, such as animate and inanimate objects. Animate objects include living beings, such as humans, animals, plants. Such models may comprise a wire frame formed of body segments movably connected with three-way, two-way and one-way joints. The frame may be wrapped with an additional wire. The joints may also include multi-axial joints. | 2014-09-25 |
20140287402 | METHOD FOR SCREENING CELLS - The invention relates to high throughput screening methods for identifying, isolating and retrieving cells secreting antibodies of interest, e.g., having functional activity and/or multi-antigen specificities. It further provides methods for the cloning of said antibodies VH/VL sequences and the generation of recombinant monoclonal antibodies derived thereof having the features of interest. | 2014-09-25 |
20140287403 | NANOSCALE MOTION DETECTOR - Motion detector comprising a flexible support ( | 2014-09-25 |
20140287404 | DETECTION OF BISULFITE CONVERTED NUCLEOTIDE SEQUENCES - The invention is to improved compositions and methods for the detection of target bisulfite converted methylated nucleotide sequences. | 2014-09-25 |
20140287405 | METHOD FOR DETECTING AND QUANTIFYING WHEAT ENDOGENOUS GENE - Provided is a method of detecting or quantifying a wheat species-specific DNA in a test sample by polymerase chain reaction. The method comprises a step of amplifying a nucleic acid molecule having a partial sequence of a nucleotide sequence identified as SEQ ID NO: 1 using a nucleic acid molecule in the test sample or a nucleic acid molecule extracted from the test sample as the template and using a primer pair capable of amplifying the partial sequence and a step of detecting or quantifying the amplified nucleic acid molecule. | 2014-09-25 |
20140287406 | CORN PLANT MON88017 AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF - The present invention provides a corn plant designated MON88017 and DNA compositions contained therein. Also provided are assays for detecting the presence of the corn plant MON88017 based on a DNA sequence and the use of this DNA sequence as a molecular marker in a DNA detection method. | 2014-09-25 |
20140287407 | SYSTEM AND METHOD FOR ANALYSIS OF PLANT MATERIAL FOR A SET OF UNIQUE EXOGENOUS GENETIC ELEMENTS - This disclosure concerns a system and method for detecting heterologous DNA in plant materials. | 2014-09-25 |
20140287408 | TARGET SEQUENCE ENRICHMENT - The present invention provides methods, systems, kits, and compositions for magnetically purifying target nucleic acid sequences from a sample using bait molecules configured to bind both target nucleic acid sequences and magnetic binding particles. In certain embodiments, the bait molecules comprise a short target capture sequence (e.g., 18 to 48 bases), and the methods employ a short hybridization time (e.g., 1-4 hours) and a low hybridization temperature (e.g., about room temperature). | 2014-09-25 |
20140287409 | Detection And Assessment Of Cancer Risk Using Telomere Health - Compositions and methods related to assessing the risk of cancer, such as breast cancer, lung cancer and bladder cancer, through analyzing the length of telomeres, such as chromosome 9p, 15p, and/or Xp telomere, such as the short arm of the 9p, 15p, and/or Xp telomere. | 2014-09-25 |
20140287410 | Probe:Antiprobe Compositions for High Specificity DNA or RNA Detection - Probe systems and methods are provided for detecting nucleic acid targets using labeled polynucleotide probes and antiprobes that interact together and with complementary targets. These interactions result in signaling changes that indicate target frequency and provide error-checking functions that facilitate single base discrimination. These probe:antiprobe compositions enable real-time PCR detection, end-point detection and microarray detection of microbial species, drug resistant mutants, and cancer related variants. The probe:antiprobe may be an internal probe between two primers or may be a primer-probe. The probe also may be modified by introducing a base mismatch to increase thermodynamic discrimination of a correct versus incorrect target differing by a single base. Probe systems also are provided for use in methods of increasing target amplification and detecting specific single base variants. | 2014-09-25 |
20140287411 | COMPOSITIONS, KITS AND RELATED METHODS FOR THE DETECTION AND/OR MONITORING OF LISTERIA - Provided are compositions, kits, and methods for the identification of | 2014-09-25 |
20140287412 | ACF DETECTION METHOD - The present invention provides a method for detecting ACF by analyzing a test region of large intestine tissue at the molecular level. Namely, the present invention relates to a method for detecting aberrant crypt foci (ACF) that comprises detecting an ACF detection marker in a test region of large intestine tissue, by using one or more types of molecules for which ACF-specific expression increases as the ACF detection marker, the molecule being selected from the group consisting of SLC2a1, and SLC7a7; an ACF detection marker for detecting the ACF in human-derived large intestine tissue, that is SLC2a1, or SLC7a7; and, a method for evaluating risk of colorectal cancer and colorectal adenoma in subjects based on the results of detecting ACF in a test region of large intestine tissue of the subjects using the aforementioned ACF detection method. | 2014-09-25 |
20140287413 | METHODS, COMPOSITIONS, AND DEVICES UTILIZING MicroRNA TO DETERMINE PHYSIOLOGICAL CONDITIONS - Methods, compositions, and devices are disclosed which use microRNA to detect, predict, treat, and monitor physiological conditions such as disease or injury. microRNA are isolated and their differential expression is measured to provide diagnostic information. This information may then be utilized for evaluation and/or treatment purposes. | 2014-09-25 |
20140287414 | SYSTEM AND METHOD FOR ANALYZING DNA USING APPLICATION OF MOBILE DEVICE - A DNA analysis system that controls DNA analysis by wireless using an application of a mobile device and a very small DNA analysis apparatus, and that receives a DNA analysis result in real time on the spot is provided. Therefore, by performing DNA analysis by simultaneously controlling a plurality of small DNA analysis apparatuses using signal processing and screen display functions of a mobile device, analysis speed of DNA is improved, and an analysis result of DNA can be provided in real time. Further, by forming a DNA analysis apparatus in a very small size, DNA can be immediately analyzed with low power consumption on the spot using a small sample, and the DNA analysis apparatus can be carried. | 2014-09-25 |
20140287415 | Polymerases - Modified DNA polymerases have an affinity for DNA such that the polymerase has an ability to incorporate one or more nucleotides into a plurality of separate DNA templates in each reaction cycle. The polymerases are capable of forming an increased number of productive polymerase-DNA complexes in each reaction cycle. The modified polymerases may be used in a number of DNA sequencing applications, especially in the context of clustered arrays. | 2014-09-25 |
20140287416 | POLYELECTROLYTE-COATED SIZE-EXCLUSION ION-EXCHANGE PARTICLES - A polyelectrolyte-coated particle, devices for using the particle, methods for using the particle for separating PCR reaction products and/or DNA sequencing reaction products, and compositions for coating the particle are provided. | 2014-09-25 |
20140287417 | EGFR Blood Monitoring - Improved methods of assessing status of a solid-tumor cancer in a subject involving detection of tumor-associated mutations in the subject's blood. | 2014-09-25 |
20140287418 | COMPOSITION FOR AMPLIFYING NUCLEIC ACIDS - The invention relates to a concentrated and buffered liquid composition for amplifying nucleic acids, comprising at least one dNTP, at least one enzyme required for the amplification, at least one oligonucleotide primer, and at least one fluorescent nucleotide probe, in the presence of a polyol and/or of polyvinylpyrrolidone (PVP). | 2014-09-25 |
20140287419 | Compositions Having Dicamba Decarboxylase Activity and Methods of Use - Compositions and methods comprising polynucleotides and polypeptides having dicamba decarboxylase activity are provided. Further provided are nucleic acid constructs, host cells, plants, plant cells, explants, seeds and grain having the dicamba decarboxylase sequences. Various methods of employing the dicamba decarboxylase sequences are provided. Such methods include, for example, methods for decarboxylating an auxin-analog, method for producing an auxin-analog tolerant plant, plant cell, explant or seed and methods of controlling weeds in a field containing a crop employing the plants and/or seeds disclosed herein. Methods are also provided to identify additional dicamba decarboxylase variants. | 2014-09-25 |
20140287420 | Microfluidics Polymerase Chain Reaction and High Resolution Melt Detection - The present invention relates to a method and system for Polymerase Chain Reaction (“PCR”), High Resolution Melt (“HRM”) analysis and microfluidics, and, more specifically, to a method and system for implementing the processes of PCR and HRM on a microscale in a microfluidics chamber for certain purposes including for purposes of DNA detection and/or extraction. | 2014-09-25 |
20140287421 | GENE EXPRESSION MARKERS FOR BREAST CANCER PROGNOSIS - The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of breast cancer. | 2014-09-25 |
20140287422 | Method for Selecting a Treatment for Non-Small Cell Lung Cancer Using Gene Expression Profiles - The present invention identifies and quantifies changes in gene expression associated with non-small cell lung cancer NSCLC by examining gene expression in tissue from normal lung and diseased lung. The present invention also identifies and quantifies expression profiles which serve as useful diagnostic markers as well as markers that are useful to monitor disease states, disease progression, drug toxicity, drug efficacy and drug metabolism. | 2014-09-25 |
20140287423 | DEVICE AND METHOD FOR APPORTIONMENT AND MANIPULATION OF SAMPLE VOLUMES - The present invention relates to methods and apparatus for apportionment and manipulation of sample volumes into smaller discrete volumes. The method exploits the interplay of hydrophilic and hydrophobic forces to partition sample volumes. These compartmentalized volumes allow for isolation of samples and partitioning into a localized array that can subsequently be manipulated and analyzed. The partition into extremely small volumes along with the device's inherent portability render our invention versatile for use in many areas, including but not limited to PCR, digital PCR, biological assays for diagnostics and prognostics, cancer diagnosis and prognosis, high throughput screening, single molecule and single cell reactions or assays, the study crystallization and other statistical processes, protein crystallization, drug screening, environmental testing, and the coupling to a wide range of analytical detection techniques for biomedical assays and measurements. | 2014-09-25 |
20140287424 | SLIDE CHIP FOR DETECTION SENSOR OF FOOD-BORNE PATHOGENS AND PREPARATION METHOD THEREOF - The present invention relates to a slide chip for a sensor for detection of food-borne bacteria and a fabrication method thereof. More particularly, the invention relates to a slide chip for a sensor for detection of food-borne bacteria and a fabrication method thereof, the slide chip comprising: a substrate coated with a metal; a linker having a substituent which may be bonded to the metal and is located at the 5′ end of deoxythymidine (dT); and a food-borne bacterium-derived RNA aptamer that is bound to the linker by the 3′-end poly A tail. The slide chip makes it possible to detect food-borne bacteria in a rapid and accurate manner. | 2014-09-25 |
20140287425 | GLUCOSE AND INSULIN SENORS AND METHODS OF USE THEREOF - Described herein are glucose and insulin sensors. The sensors are composed of host cells with DNA specifically designed to produce fluorescence when the cells come into contact with glucose and/or insulin in the sample. Once the fluorescence has been quantified, it can be correlated with the amount of glucose and/or insulin present in the sample. | 2014-09-25 |
20140287426 | ANTIBODY AND ANTIBODY MIMETIC FOR VISUALIZATION AND ABLATION OF ENDOGENOUS PROTEINS - Provided are compositions and methods for labeling an endogenous protein, in particular, in a live cell, or for ablating an endogenous or target protein. The compositions relate to a fusion protein having a binding moiety such as an antibody, an antigen binding fragment of an antibody or an antibody mimetic that recognizes the endogenous or target protein. | 2014-09-25 |
20140287427 | COMPOSITIONS AND METHODS FOR CAPTURE OF CELLULAR TARGETS OF BIOACTIVE AGENTS - The present invention provides compositions and methods for capture and identification of the cellular targets of a bioactive agent. In particular, provided herein are bioactive agents tethered to capture ligand, cellular targets (optionally tagged with a reporter), capture proteins (optionally present as capture dimers), surfaces (e.g., displaying, capture ligands, capture proteins, or capture dimers), and methods of capturing and identifying the cellular targets of a bioactive agent therewith. | 2014-09-25 |
20140287428 | METHOD FOR DETECTION OF BACTERIA IN MILK - A method of detecting the presence of bacteria in milk is provided, wherein milk is contacted with a preparation which may comprise an effective amount of at least one type of antibodies, said antibodies being capable of specifically binding to bacteria to be detected; staining said antibodies, before or after said contacting, with a staining preparation, said staining preparation being selected so that the antibodies stained therewith exhibit a color change or a change in color concentration when in contact with said bacteria; and determining the concentration of stained antibodies bound to bacteria in said milk from the presence and/or the relative intensity of the color change caused by contacting said milk with said stained antibodies. | 2014-09-25 |
20140287429 | PRETREATMENT SOLUTION FOR IMMUNOHISTOCHEMICAL STAINING AND CONDENSED SOLUTION THEREOF - Disclosed are a pretreatment solution for immunohistochemical staining, which elutes a paraffin-containing embedding medium from a glass slide with a tissue specimen embedded in the medium, and retrieves antigenicity of the tissue specimen, and which is usable three or more times, and a pretreatment solution concentrate for immunohistochemical staining which allows ready preparation of the pretreatment solution and a method of immunohistochemical staining using the same. The pretreatment solution contains an antigen retrieving agent, particular nonionic surfactants, and cyclodextrin or a derivative thereof, with the balance being not less than 80 mass % of water. The content of the antigen retrieval agent is such that the pH of the pretreatment solution is in a predetermined range, and the content of cyclodextrin or a derivative thereof is a particular amount. | 2014-09-25 |
20140287430 | ABSORBENT PAPER AND USE THEREOF FOR BREAST CANCER DETECTION - Biological samples of mammary fluid or components thereof are obtained using a breast pump device coupled with an absorbent paper or membrane, optionally facilitated by administering oxytocin to the subject. The breast pump device stimulates expression of mammary fluid and provides for collection of diagnostic samples on the absorbent paper or membrane to evaluate breast disease, including cancer. The biological sample may include fluid containing one or more of cells or cellular components, proteins, glycoproteins, peptides, nucleotides or other desired constituents comprising a breast disease marker. Absorbent paper or membrane, and methods relating to the paper or membrane, and a breast pump device are also provided. | 2014-09-25 |
20140287431 | ANTIBODY SPECIFIC TO PROFILAGGRIN C-TERMINAL DOMAIN, AND USE THEREOF - The present invention provides an antibody specific to a C-terminal domain of a human profilaggrin gene, wherein the C-terminal domain is a peptide comprising the amino acid sequence set forth in SEQ ID NO:1 or a variant thereof, a method for detecting a filaggrin gene mutation using the antibody, and a kit for the detection. | 2014-09-25 |
20140287432 | Diagnosis, Prevention and Treatment of Disorders Characterized by Undesirable Cell Proliferation - The present invention relates to methods for the diagnosis, prevention and treatment of heart disease or heart failure in a subject. The present invention also relates to methods for the diagnosis, prevention and treatment of atherosclerosis with vulnerable plaque in a subject. Furthermore, the present invention relates to methods for the diagnosis, prevention and treatment of cardiomyopathies resulting from Chagas disease. | 2014-09-25 |
20140287433 | MEANS AND METHODS FOR DETERMINING CLOSTRIDIAL NEUROTOXINS - This invention relates to a method of determining presence, amount and/or activity of a clostridial neurotoxin in a sample, the method comprising or consisting of the following steps: (a) bringing said sample into contact with a liposome, said liposome comprising (aa) at least one receptor on its outer surface, said receptor being capable of binding said neurotoxin and comprising or consisting of (i) a glycolipid and (ii) a peptide or protein; and (ab) a substrate in its interior, said substrate (i) being cleavable by the peptidase comprised in said neurotoxin and (ii) generating a detectable signal upon cleavage, said detectable signal preferably being generated by (1) the donor of a FRET pair, said donor exhibiting increased fluorescence upon cleavage by said peptidase, (2) a luminescent compound formed upon said cleavage, or (3) an enzyme formed upon said cleavage; and (b) determining whether an increase in signal occurs as compared to the absence of said sample, wherein such increase is indicative of the presence of said neurotoxin and/or the degree of such increase is indicative of the amount and/or activity of said neurotoxin in said sample. | 2014-09-25 |
20140287434 | METHODS OF SCREENING FOR AND IDENTIFYING COMPOSITIONS WHICH MODULATE CELLULAR KINASE ACTIVITIES - The present invention relates to drug screening assays, therapeutic protocols and pharmaceutical compositions designed to target non-receptor tyrosine family kinases and components of the tyrosine kinase family signal transduction pathways. This includes primarily diseases or conditions associated with immune responses and can include treatment for cancers as well as various immune disorders. The invention reports a novel substrate SH2 domain docking mechanism apart from the kinase active site that is required for appropriate tyrosine phosphorylation by these tyrosine kinases. | 2014-09-25 |
20140287435 | KITS, COMPOSITIONS AND METHODS FOR DETECTING A BIOLOGICAL - The present invention provides kits, apparatus and methods for determining a biological condition in a mammalian subject, the method includes incubating a specimen from a patient with at least one composition in a kit for a predetermined period of time to form at least one reaction product, when the subject has said biological condition, and receiving an indication of the at least one reaction product responsive to at least one reporter element in the kit thereby providing the indication of the biological condition in the subject. | 2014-09-25 |
20140287436 | Physical Removal Of Biological Agents Detected By A Magnecytometer - A system and method for analyzing a sample of liquid having an NMR signal in response to a magnetic field for the presence of an analyte. Included is an NMR device having a testing section that is adapted to contain a liquid and apply a magnetic field to the liquid. A complex comprised of a conjugate having a field gradient bound to the analyte that is of sufficient magnitude to quench the NMR signal of the liquid, when in the test section whereby the presence of the complex is determined by the absence of the NMR signal. The system and method also include a container having a binding agent therein that has an affinity for the analyte or foreign agent that is used to remove the foreign agent from a patient's blood or plasma. Blood or plasma is shunted through the container to remove or reduce the foreign agent by extracorporeal circulation. | 2014-09-25 |
20140287437 | MAGNETIC SEPARATION OF CELLS - An apparatus, system, and method for magnetic separation of cells are disclosed. By combining inkjet printing technology and magnetic labeling of cells, accurate cell counts are obtained using an optical microscope. Mouse CD4+ lymphocytes are attached to micron sized magnetic beads and printed through a modified, commercial inkjet printer. The labeled cells are then attached to a glass slide covering a permanent magnet. Cell counts can be obtained by use of regular and inverted optical microscopes and imaging software. The magnetically-labeled beads are collected for evaluation on a modified polymer coupon that is placed in front of a permanent magnet and the unlabeled cells fall into an excess container. Flow cytometry results verify the presence of the CD4+ protein on the LBRM-33 lymphocytes membrane. Protein-specific attachment of magnetic microspheres to the lymphocytes is utilized for sorting CD4+ lymphocytes. | 2014-09-25 |
20140287438 | Rapid and Inexpensive Assay for Evaluation of Antibody Efficacy with Custom-Designed Fluorescent Nanoparticles - A method for determining the efficacy of a vaccine comprising: providing serum from an animal inoculated with a vaccine; providing a plurality of antigen-linked nanoparticles; contacting the serum with the plurality of antigen linked nanoparticles; contacting the serum and the plurality of antigen linked nanoparticles with a plurality of Fc receptor-expressing cells; measuring amount antigen-linked nanoparticle uptake by of the Fc receptor-expressing cells; determining efficacy of the vaccine by comparing the level of antigen-linked nanoparticle uptake to a baseline level of uptake wherein a greater nanoparticle uptake compared to the baseline level of uptake is indicative of greater vaccine efficacy. | 2014-09-25 |
20140287439 | METHOD FOR MANUFACTURING MULTIPLE-DIAGNOSIS MEMBRANE SENSOR BY USING SCREEN PRINTING - Provided is a method for manufacturing a multiple-diagnosis membrane sensor provided with multiple channels by using screen printing, and more specifically, to a method for manufacturing a membrane sensor capable of performing multiple-diagnosis by screen-printing hydrophobic ink on a membrane to form multiple channels. | 2014-09-25 |
20140287440 | Melittin Peptide Conjugates and Methods Employing Same - Methods and reagents are disclosed for conducting assays for IgE specific for honey bee venom allergen. A reagent comprises a conjugate of a small molecule linked to a terminal glycine amino acid of a synthetic 26 amino acid melittin peptide. In the method a combination is provided that comprises a sample and the aforementioned reagent. The combination is subjected to conditions for binding of IgE specific for honey bee venom allergen to the reagent to form a complex. One or both of the presence and amount of the complex is detected and related to one or both of the presence and amount in the sample of IgE specific for honey bee venom allergen. | 2014-09-25 |
20140287441 | IMMUNOASSAY FOR CYCLOPROPYLINDOLE BASED SYNTHETIC CANNABINOIDS, METABOLITES AND DERIVATIVES THEREOF - The invention relates to the detection and quantification of cyclopropylindole based synthetic cannabinoids UR-144 and XLR-11 by providing antibodies based on novel immunogens. These antibodies can be incorporated into methods and kits for the detection of UR-144, XLR-11 and their metabolites. | 2014-09-25 |
20140287442 | METHOD FOR DETERMINING DEGREE OF MODIFIED POTENCY OF BIPATHIC MEDICAMENT - The invention comprises a method for determining degree of modified potency of a bipathic medicament. A bipathic medicine is a medicament comprising a therapeutic component and a homeopathic component, wherein the homeopathic component has some physical, chemical or biological affect on the therapeutic component and/or the pharmacological efficacy thereof. An analytical measurement of at least one characteristic parameter of the therapeutic form is made prior to its interaction with the activated-potentiated form. The same analytical measurement(s) are made and after interaction between the therapeutic and activated-potentiated forms. This data is used to confirm the presence of any modified potency is caused by the presence of molecular form in the activated-potentiated form. Further, the claimed analytical measurement of at least one characteristic parameter of the therapeutic form prior to its interaction with the activated-potentiated form and again after such interaction serves to quantify the degree of modifying potency associated with the activated-potentiated form in relative dimensionless activity units (release activity). | 2014-09-25 |
20140287443 | CHARACTERIZATION OF CHO-MIF GENE AND PROTEIN, AND USE THEREOF - The present invention is concerned with the specific and highly sensitive detection of specific CHO-MIF (macrophage migration inhibitory factor from Chinese Ovarian Hamster cell line) complexes in the production of anti-MIF antibodies. The present invention is further concerned with the provision of specific antibodies which can be used for a CHO-MIF detection method. The present invention is also concerned with a CHO MIF knockout cell line and use thereof. The present invention also provides preparations obtained from recombinant production in CHO cell lines which are essentially free of CHO-MIF. | 2014-09-25 |
20140287444 | METHOD OF LIPID ASSAY AND REAGENT FOR USE THEREIN - A method of lipid assay characterized by assaying the lipids contained in a blood component in the presence of an organic silicon compound. The method can cause specific conditions for direct methods while satisfying requirements such as no influence on precision of assay, no burden on assay apparatus, and easy availability. | 2014-09-25 |
20140287445 | FLAVIN-BINDING GLUCOSE DEHYDROGENASE, METHOD FOR PRODUCING FLAVIN-BINDING GLUCOSE DEHYDROGENASE, AND GLUCOSE MEASUREMENT METHOD USING THEREOF - A flavin-binding glucose dehydrogenase (FAD-GDH), which in addition to having high substrate specificity and adequate desirable heat stability, is suitable for efficient production, preferably using | 2014-09-25 |
20140287446 | Monoclonal Antibody For Acetylamantadine - A method of producing an antibody comprises immunizing a mammal with an amine-derivative of acetylamantadine, immunizing the mammal with acetylamantadine, and producing the antibody from the mammal. The antibody recognizes acetylamantadine but does not recognize amantadine. | 2014-09-25 |
20140287447 | Ultrasensitive methodology for quantifying the kinase catalytic activity of any protein kinase in biological/clinical samples or recombinant/purified proteins using near-infrared-fluorescence (NIRF)-labeled, kinase-selective peptide substrates and a combination of kinase-selective inhibitors to define individual kinase activity - A non-radioactive, ultrasensitive methodology for the quantification of protein kinase catalytic activity of any protein kinase in, for example, biological/clinical samples or recombinant/purified proteins, based on using near-infrared-fluorescence (NIRF)-labeled peptide substrates that are selective for individual protein kinases and using a combination of kinase-selective inhibitors to define the catalytic activity of individual protein kinases, including but not limited to, a substrate for phosphorylation by a protein kinase comprising a core peptide having the formula: (N-terminus)-Arginine-Lysine-Arginine-Serine-Arginine-Lysine-Glutamic-acid-(C-terminus); and an indicator component covalently bonded to the core peptide. | 2014-09-25 |
20140287448 | METHOD FOR DETERMINING DEGREE OF MODIFIED POTENCY OF A MEDICAMENT - The invention comprises a method for determining degree of modified potency of a medicament. A medicine is a medicament comprising a therapeutic component and a homeopathic, i.e., activated-potentiated, component, wherein the activated-potentiated component has some physical, chemical or biological affect on the therapeutic component and/or the pharmacological efficacy thereof. The therapeutic component is biologically related to the starting substance of the homeopathic component. An analytical measurement of at least one characteristic parameter of the therapeutic form is made prior to its interaction with the activated-potentiated form. The same analytical measurement(s) are made and after interaction between the therapeutic and activated-potentiated forms. This data is used to confirm the presence of any modified potency is caused by the presence of molecular form in the activated-potentiated form. Further, the claimed analytical measurement of at least one characteristic parameter of the therapeutic form prior to its interaction with the activated-potentiated form and again after such interaction serves to quantify the degree of modifying potency associated with the activated-potentiated form in relative dimensionless activity units (release activity). | 2014-09-25 |
20140287449 | Photosynthetic microorganism condition detection sensor - The present invention provides an optical probe apparatus and method for microorganism culture monitoring. The optical probe can be immersed within the microorganisms and include at least one emitter and at least two detectors that excite photosynthetic pigments in the culture medium. The optical probe can measure the culture spectral characteristics, targeting those that are an indication of the healthiness and productivity condition. The optical probe can also include a microcontroller and storage. The microcontroller can compare past measurements of the optical probe with current measurements and determine a health status of the microorganisms. The optical probe is optimized to measure spectral characteristics from the microorganism in real time. The present invention relates to a sensor tune to detect the healthiness condition of photosynthetic microorganisms. | 2014-09-25 |
20140287450 | Methods for Natural Product Optimization - Methods and compositions for natural product optimization are provided. In particular, methods and compositions for selecting bacterial strains (e.g., predatory bacteria such as myxobacteria) which produce a desired compound (e.g., antibiotic, antifungal, or anticancer agent) are provided. | 2014-09-25 |
20140287451 | FLOW CHAMBERS, METHODS OF USING THE FLOW CHAMBER, AND METHODS OF MAKING THE FLOW CHAMBER - In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure, in one aspect, relate to a device (or “flow chamber”), methods of making a device, methods of using a device, and the like. | 2014-09-25 |
20140287452 | METHOD FOR OBSERVING STEM CELLS, METHOD FOR REMOVAL OF CELL REGION IN STATE TENDING TOWARD DIFFERENTIATION, AND DEVICE FOR OBSERVING STEM CELLS - A method for observing stem cells by an observation device | 2014-09-25 |
20140287453 | SAMPLE INJECTION DEVICE FOR BIOCHEMICAL ANALYSIS, FLOW-TYPE BIOCHEMICAL ANALYSIS DEVICE, AND MEASUREMENT METHOD FOR HEMOGLOBIN COMPONENT - When injecting a sample into carrier-liquid channels ( | 2014-09-25 |
20140287454 | SUSCEPTIBILITY TO SELECTIVE CDK9 INHIBITORS - The present invention relates to a method of selecting (a) cell(s), (a) tissue(s) or (a) cell culture(s) with susceptibility to a selective CDK9 inhibitor. Also a method for determining the responsiveness of a mammalian tumor cell or cancer cell to treatment with a selective CDK9 inhibitor is described herein. In particular, the present invention provides for an in vitro method for the identification of a responder for or a patient sensitive to a selective CDK9 inhibitor, whereby the patient is suspected to suffer from NUT midline carcinoma (NMC). The present invention also relates to a method of monitoring or predicting the efficacy of a treatment of NUT midline carcinoma (NMC), wherein treatment with a selective CDK9 inhibitor is in particular envisaged. Also the use of a (transgenic) non-human animal or a (transgenic) cell having at least one rearrangement in the NUT gene for screening and/or validation of a medicament for the treatment NUT midline carcinoma (NMC) is described. Furthermore, a kit useful for carrying out the methods described herein as well as an oligo- or polynucleotide capable of detecting rearrangements in the NUT gene are provided. | 2014-09-25 |
20140287455 | MICROORGANISM DETECTING DEVICE EVALUATION KIT, MICROORGANISM DETECTING DEVICE EVALUATION KIT MANUFACTURING METHOD, AND MICROORGANISM DETECTING DEVICE EVALUATING METHOD - An evaluation kit for a microorganism detecting device includes an immobilized microorganism. A manufacturing method for an evaluation kit for a microorganism detecting device includes immobilizing a microorganism. An evaluating method for the microorganism detecting device includes detecting an immobilized microorganism by the microorganism detecting device. The immobilized microorganisms may be dispersed in a solvent. The solvent may be water. The immobilized microorganisms may be immobilized with an aldehyde. The aldehyde may be formaldehyde. The immobilized microorganisms emit, for example, fluorescent light. | 2014-09-25 |
20140287456 | METHOD OF REMOVING FLOATATION LIQUID - A method of removing a floatation liquid from between a microscope slide and a paraffin embedded biological specimen including position the microscope slide with the paraffin embedded biological specimen floated thereon onto a slide support element. The slide support element is rotated to cause the microscope slide and the paraffin embedded biological specimen to turn in a way that causes the floatation liquid disposed between the microscope slide and the paraffin embedded biological specimen to be drawn from between the microscope slide and the paraffin embedded biological specimen. | 2014-09-25 |
20140287457 | SYNTHETIC GENES FOR PLANT GUMS AND OTHER HYDROXYPROLINE-RICH GLYCOPROTEINS - A new approach in the field of plant gums is described which presents a new solution to the production of hydroxyproline(Hyp)-rich glycoproteins (HRGPs), repetitive proline-rich proteins (RPRPs) and arabinogalactan-proteins (AGPs). The expression of synthetic genes designed from repetitive peptide sequences of such glycoproteins, including the peptide sequences of gum arabic glycoprotein (GAGP), is taught in host cells, including plant host cells. | 2014-09-25 |
20140287458 | PHOTOSYNTHETIC PROCESS - The present invention provides a method of producing a photosynthetic product, the method comprising maintaining a photosynthetic plant or algal cell suspension culture, in the presence of water, light and a carbonic acid-enriched growth medium. The carbonic acid may, for example be provided by feeding the photosynthetic plant cell suspension culture with a carbonic acid solution, a solid or liquid precursor thereof, or a gaseous mixture of carbon dioxide and one or more other gases. The invention also provides a method for producing a photosynthetic product, the method comprising maintaining a photosynthetic plant or algal cell suspension culture, in the presence of water, light and a carbon source selected from carbon dioxide and carbonic acid, wherein the culture is maintained at a pH of less than 7.0, preferably 4.5 to 5.5. | 2014-09-25 |
20140287459 | TEMPERATURE SHIFT FOR HIGH YIELD EXPRESSION OF POLYPEPTIDES IN YEAST AND OTHER TRANSFORMED CELLS - Methods for producing heterologous proteins are disclosed. In particular, the present disclosure provides improved methods of producing desired proteins, including multi-subunit proteins such as antibodies, with a higher yield and improved purity. In exemplary embodiments, the transformed cells are a yeast, e.g., methylotrophic yeast such as | 2014-09-25 |
20140287460 | PRODUCTION OF RECOMBINANT PROTEIN IN INSECT CELLS USING A BACULOVIRUS EXPRESSION SYSTEM - The present invention describes a novel method for recombinant protein production using a baculovirus protein expression system in insect cells, wherein baculovirus virion production is suppressed during recombinant protein production. The novel expression system produces reduced levels of baculovirus virions during recombinant protein production phase, thereby reducing the need for purification of the recombinant protein from the contaminating virus. The novel baculovirus expression system may further suppress expression of recombinant protein by baculovirus-infected cells during virus amplification prior to induction, thereby reducing selection pressure on the expression cassette for the recombinant protein. | 2014-09-25 |
20140287461 | METHOD FOR PRODUCING SUGAR LIQUID - A method of producing a sugar liquid using a cellulose-containing biomass as a raw material includes (a) hydrolyzing a cellulose-containing biomass to produce an aqueous sugar solution and (b) filtering the obtained aqueous sugar solution through a reverse osmosis membrane to collect a purified sugar liquid from a feed side, while removing fermentation-inhibiting substances from a permeate side. | 2014-09-25 |
20140287462 | GENE INACTIVATED MUTANTS WITH ALTERED PROTEIN PRODUCTION - A recombinant filamentous fungal cell (e.g. | 2014-09-25 |
20140287463 | ENGINEERED PICHIA STRAINS WITH IMPROVED FERMENTATION YIELD AND N-GLYCOSYLATION QUALITY - The present invention relates to novel engineered | 2014-09-25 |
20140287464 | In Vivo Unnatural Amino Acid Expression in the Methylotrophic Yeast Pichia Pastoris - The invention provides orthogonal translation systems for the production of polypeptides comprising unnatural amino acids in methylotrophic yeast such as | 2014-09-25 |
20140287465 | Polypeptides Having Xylanase Activity and Polynucleotides Encoding Same - The present invention relates to polypeptides having xylanase activity, catalytic domains, and carbohydrate binding domains, and polynucleotides encoding the polypeptides, catalytic domains, and carbohydrate binding domains. The present invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains, and carbohydrate binding domains. | 2014-09-25 |
20140287466 | PROCESS FOR THE CONVERSION OF LIGNOCELLULOSE MATERIAL INTO AN ORGANIC ACID - The invention relates to a process for the conversion of lignocellulose into an organic acid including an alkaline pretreatment step and a fermentation step, wherein liquid phase obtained in the fermentation step is recycled to the alkaline pretreatment step and/or the fermentation step. Organic acid is recovered as its magnesium of calcium salt from solid phase obtained in the fermentation step. | 2014-09-25 |
20140287467 | PROCESSING BIOMASS - Feedstocks, obtained at least in part from a plant material that has been modified with respect to its wild type, are processed to produce useful intermediates and products, such as energy, fuels, foods or materials. For example, systems are described that can treat such feedstock materials, e.g., to reduce the recalcitrance of the feedstock, and use the treated feedstock materials to produce an intermediate or product, e.g., by saccharification and/or fermentation. | 2014-09-25 |
20140287468 | Enrichment of Target Sequences - Methods and compositions are provided for enriching for target sequences from a population of nucleic acids, that includes combining in solution, a population of nucleic acids and a target isolation probe wherein the target isolation probe includes an affinity binding domain; permitting a single stranded region of the target isolation probe to hybridize to all or a portion of a target sequence in the population of nucleic acids; selectively immobilizing the hybridized nucleic acids from the population containing the target sequences by associating the target isolation probe with a capture domain and removing unbound material; and removing from the 3′ end of the target sequence, a non-target sequence by means of one or more 3′ single strand specific exonucleases. Target enrichment may be used to detect variations in nucleotide sequence for detecting phenotypic changes related to health or disease. | 2014-09-25 |
20140287469 | FILTRATION - Biomass feedstocks (e.g., plant biomass, animal biomass, and municipal waste biomass) are processed to produce useful products, such as fuels. For example, systems are described that can be useful for separating solids from liquids of saccharified biomass material slurries. | 2014-09-25 |
20140287470 | PROCESSING BIOMASS AND ENERGY - Biomass feedstocks (e.g., plant biomass, animal biomass, and municipal waste biomass) are processed to produce useful products, such as fuels, heat and energy. | 2014-09-25 |
20140287471 | VARIANT CBH I POLYPEPTIDES WITH REDUCED PRODUCT INHIBITION - The present disclosure relates to variant CBH I polypeptides that have reduced product inhibition, and compositions, e.g., cellulase compositions, comprising variant CBH I polypeptides. The variant CBH I polypeptides and related compositions can be used in variety of agricultural and industrial applications. The present disclosure further relates to nucleic acids encoding variant CBH I polypeptides and host cells that recombinantly express the variant CBH I polypeptides. | 2014-09-25 |
20140287472 | Method for Producing L-Amino Acids Using Bacteriua of the Enterobacteriaceae Family - There is disclosed a method for producing L-amino acid, for example L-threonine, L-lysine, L-histidine, L-phenylalanine, L-arginine or L-glutamic acid, using a bacterium of the Enterobacteriaceae family, wherein the bacterium has been modified to enhance an activity of D-xylose permease. | 2014-09-25 |
20140287473 | METHODS AND COMPOSITIONS FOR ENHANCED PRODUCTION OF ORGANIC SUBSTANCES FROM FERMENTING MICROORGANISMS - The present invention relates methods and compositions for producing an organic substance from fermenting microorganism using simultaneous saccharification and fermentation. One aspect of the invention provides producing alcohol by simultaneous saccharification and fermentation by combining a cellulosic substrate, and whole fermentation broth, and an ethanologenic microorganism under conditions conducive both to hydrolysis of cellulose to glucose and to conversion of glucose to alcohol. | 2014-09-25 |
20140287474 | METHOD OF TREATING ORGANIC MATERIAL TO PRODUCE METHANE GAS - The present invention relates to a method of treating organic materials to produce methane gas, comprising the steps of: a) subjecting an organic feedstock comprising organic materials to a liquefaction process at subcritical conditions in at least one reaction stage, to obtain a mixture containing low molecular weight materials and optionally lignins; b) subjecting the obtained mixture containing low molecular weight materials and optionally lignins, to a methane fermentation process; wherein said organic feedstock comprises liquid water and/or is combined with liquid water before and/or during said liquefaction, and the subcritical conditions for said at least one or more reaction stage(s) in a) is a temperature of 280-374° C. during a reaction time of less than 1 minute, wherein if more than one reaction stage is used in step a) the obtained mixture after each reaction stage is subjected to a separation of the produced low molecular weight materials from the remaining solid materials of the treated feedstock. | 2014-09-25 |
20140287475 | Methods For Eliminating Or Reducing The Expression Of A Gene In A Filamentous Fungal Strain - The present invention relates to methods for reducing or eliminating the expression of a target gene in a filamentous fungal strain, comprising: (a) inserting into the genome of the filamentous fungal strain a double-stranded transcribable nucleic acid construct comprising a first nucleotide sequence comprising a promoter operably linked to a homologous coding region of the target gene and a second nucleotide sequence comprising the homologous coding region, or a portion thereof, of the target gene, wherein the first and second nucleotide sequences are complementary to each other and the second nucleotide sequence is in reverse orientation relative to the first nucleotide sequence; and (b) inducing production of an interfering RNA encoded by the double-stranded transcribable nucleic acid construct by cultivating the filamentous fungal strain under conditions conducive for production of the interfering RNA; wherein the interfering RNA interacts with RNA transcripts of the target gene to reduce or eliminate expression of the target gene. The present invention also relates to the filamentous fungal strains and to methods of producing a biological substance of interest in such filamentous fungal strains. | 2014-09-25 |
20140287476 | VIBRIO CHOLERAE 0139 CONJUGATE VACCINES - The disclosure pertains to conjugates of the capsular polysaccharide of | 2014-09-25 |