| 38th week of 2010 patent applcation highlights part 36 |
| Patent application number | Title | Published |
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| 20100239461 | Self-Running Sample Holder and System Having Self-Running Sample Holders - A self-running sample holder includes a holder main body, a motor provided in the holder main body, a wheel, a transceiver and a battery. The holder main body has a holder portion which holds a sample with recorded information in an upright state. The wheel is provided in the holder main body and rotated in conjunction with the motor. The motor allows the self-running sample holder to self-run in an upright state. The transceiver is provided in the holder main body. The transceiver outputs a drive signal and drive stop signal to the motor in response to a signal from an external controller. The transceiver exchanges a signal with the controller. The battery is provided in the holder main body. The battery supplies the motor and transceiver with electricity. The battery is chargeable. | 2010-09-23 |
| 20100239462 | Assembly of at Least One Microfluidic Device and Mounting Piece - An assembly comprising at least one microfluidic device and a mounting piece, this microfluidic device comprising at least one material layer and at least one first fluidic port, which first fluidic port it situated at least partially in an end surface of the material layer and which mounting piece comprises at least one fluidic component, wherein the mounting piece is coupled to the microfluidic device by means of first coupling means provided for this purpose such that the fluidic component is connected to the first fluidic port. The invention also relates to such a mounting piece. | 2010-09-23 |
| 20100239463 | LEAD-FREE PIEZOELECTRIC CERAMIC FILMS AND A METHOD FOR MAKING THEREOF - This invention relates to lead-free piezoelectric ceramic films and a method of making thereof. Specifically, the invention is directed to a method for fabricating lead-free piezoelectric free standing films having enhanced piezoelectric properties. The films may be used for a number of applications including incorporation in microelectronic devices such as energy harvesting devices and sensor technologies. | 2010-09-23 |
| 20100239464 | SUBSTRATE MANUFACTURING METHOD FOR SENSOR APPLICATIONS USING OPTICAL CHARACTERISTICS AND THE SUBSTRATE THEREFROM - A method for manufacturing a substrate of an analytical sensor and the substrate thus prepared are disclosed. The method for manufacturing the substrate of the sensor application according to the present invention is characterized in that it comprises (a) the step of preparing a dispersed solution of nanoparticles, which are stable in a volatile organic solvent due to surface modification of nanoparticles having a pre-designed certain size on the nanometer level with an organic functional group (b) the step of preparing a single layer film of nanoparticles surface-modified with the organic functional group on the interface using said dispersed solution of nanoparticles on the basis of the Langmuir-Blodgett method, and then transferring said single layer film of nanoparticles to the substrate; and (c) the step of coating the substrate to which said single layer film of nanoparticles is transferred, with the metal thin film by means of the vacuum vapor deposition, and then optionally removing nanoparticles to manufacture a nanostructure to be used as the analytical sensor using optical characteristics. According to the method for manufacturing the substrate of the sensor application according to the present invention as above, the nanoparticles can be uniformly fixed on the solid substrate having a great area above 10×10 cm | 2010-09-23 |
| 20100239465 | Fluorescence Sensor for Detecting Gas Compositions - A fluorescent sensor for the detection of gas compositions has a carrier substrate and a fluorescent layer. The carrier substrate and fluorescent layer consists of a gas-permeable polymer matrix with an embedded fluorescent dye. A diffusion layer of gas-permeable ceramics and/or polymers is arranged over the fluorescent layer and is adapted to cause a time delay of the gas diffusion from a detected-environment to the fluorescent layer and from the fluorescent layer to a detected-environment. | 2010-09-23 |
| 20100239466 | Surface Plasma Gas Processing - The invention relates to a gas processing unit adapted for generating a surface plasma in the vicinity of a photocatalyst, that has a planar configuration. The photocatalyst is deposited in the form of a thin layer on a dielectric substrate and at least one plasma supply electrode is formed above the photocatalyst thin layer. Such a configuration increases the interaction between the plasma and the photocatalyst. The unit can be used for a gas processing of the pollution-control, odour reduction or bactericidal treatment type with a high efficiency. | 2010-09-23 |
| 20100239467 | METHODS AND SYSTEMS FOR UTILIZING WASTE SOURCES OF METAL OXIDES - Methods are provided for producing a composition comprising carbonates, wherein the methods comprise utilizing waste sources of metal oxides. An aqueous solution of divalent cations, some or all of which are derived from a waste source of metal oxides, may be contacted with CO | 2010-09-23 |
| 20100239468 | EXHAUST GAS PURIFYING APPARATUS AND METHOD FOR MANUFACTURING EXHAUST GAS PURIFYING APPARATUS - An exhaust gas purifying apparatus includes an exhaust gas treating body, a metal casing, and a holding sealing material. The exhaust gas treating body has a longitudinal direction and includes cell walls extending along the longitudinal direction to define cells between the cells. The metal casing has an inner surface and houses the exhaust gas treating body to face the inner surface. The holding sealing material is provided between the exhaust gas treating body and the inner surface of the metal casing to hold the exhaust gas treating body in the metal casing. The holding sealing material includes an inorganic fiber aggregated body. The metal casing has a corrosion area at least on a part of the inner surface. The corrosion area includes a corroded base material of the metal casing. | 2010-09-23 |
| 20100239469 | Monolithic exhaust treatment unit for treating an exhaust gas - A monolithic exhaust treatment device on unit ( | 2010-09-23 |
| 20100239470 | Photocatalysts Based on Structured Three-Dimensional Carbon or Carbon-Containing Material Forms - The invention relates to a photocatalyst comprising a cellular foam selected from carbon foam and the foam of a carbon material, such as a polymer, and a photocatalytically active phase, deposited directly on said cellular foam or on an intermediate phase deposited on said cellular foam. The average size of the cells is between 2500 μm and 5000 μm. The foam can comprise nanotubes or nanofibers (in particular TiO | 2010-09-23 |
| 20100239471 | CASSETTE FOR SAMPLE PREPARATION - A cassette for preparing a sample is disclosed herein. The cassette includes a housing, which encloses the structures and the processes used to prepare the sample. | 2010-09-23 |
| 20100239472 | REACTOR | 2010-09-23 |
| 20100239473 | APPARATUS FOR DECOMPOSING ORGANIC MATTER WITH RADICAL TREATMENT METHOD USING ELECTRIC DISCHARGE - An apparatus performs radical treatment by electric discharge. The radical treatment apparatus includes an electrode unit having a gas flow path that blows gas onto treatment water and an electrode member that generates the electric discharge at a leading edge in order to generate a radical from the gas. | 2010-09-23 |
| 20100239474 | SYNTHESIS REACTION SYSTEM - There is provided a synthesis reaction system which synthesizes a hydrocarbon compound by a chemical reaction of a synthesis gas including hydrogen and carbon monoxide as main components, and a slurry having solid catalyst particles suspended in liquid and which extracts the hydrocarbon compound from the slurry. The synthesis reaction system includes a reactor main body which accommodates the slurry, a separator which separates the hydrocarbon compound included in the slurry from the slurry, a first flow passage which allows the slurry including the hydrocarbon compound to flow to the separator from the reactor main body, a second flow passage which allows the slurry to flow to the reactor main body from the separator, and a fluid supply nozzle which supplies a fluid toward at least any one of the separator, the first flow passage, and the second flow passage. | 2010-09-23 |
| 20100239475 | Apparatus for Feed Preheating with Flue Gas Cooler - Hydrocarbon feed to a catalytic reactor can be heat exchanged with flue gas from a catalyst regenerator. This innovation enables recovery of more energy from flue gas thus resulting in a lower flue gas discharge temperature. As a result, other hot hydrocarbon streams conventionally used to preheat hydrocarbon feed can now be used to generate more high pressure steam. | 2010-09-23 |
| 20100239476 | CARTRIDGE-TYPE DISPENSER - The present invention relates to improved cartridge-type dispenser for a chemical treatment composition which, when contacted with water or other liquid will at least partially dissolve or disperse, and thereby elute one or more chemical compounds to the water or other liquid. The improved cartridge-type dispense may be used itself, or in conjunction with a further apparatus. | 2010-09-23 |
| 20100239477 | Method of decarbonation and its use in producing crystalline sodium sulfite or other alkali products - A sodium sulfite liquor is formed by reacting sodium carbonate with sulfur dioxide. A CO | 2010-09-23 |
| 20100239478 | FILTER - A filter for filtering particulate matter (PM) from exhaust gas emitted from a positive ignition engine, which filter comprising a porous substrate having inlet surfaces and outlet surfaces, wherein the inlet surfaces are separated from the outlet surfaces by a porous structure containing pores of a first mean pore size, wherein the porous substrate is coated with a washcoat comprising a plurality of solid particles wherein the porous structure of the washcoated porous substrate contains pores of a second mean pore size, and wherein the second mean pore size is less than the first mean pore size. | 2010-09-23 |
| 20100239479 | Process For Removing Toxic Metals From A Fluid Stream - A process for removing at least one of As, Cd, Hg and Se from a fluid stream, comprising: (I) providing a plurality of Group A particles of a Group A sorbent material, said Group A sorbent material comprising: an activated carbon matrix defining a plurality of pores; sulfur; and an additive adapted for promoting the removal of at least one of As, Cd, Hg and Se from a fluid stream, wherein the additive is distributed throughout the activated carbon matrix; and (II) contacting the fluid stream with a plurality of Group A particles of the Group A sorbent material. The process can involve powder injection, a packed sorbent bed, a fluidized sorbent bed, and combinations thereof. | 2010-09-23 |
| 20100239480 | Method And Apparatus For The Treatment Of Nitrogen Oxides Using An Ozone And Catalyst Hybrid System - The present invention is a method of treating nitrogen oxides using an ozone and catalyst hybrid system, as well as an apparatus, specifically relating to a method of treating nitrogen oxide using an ozone and catalyst hybrid system comprising: | 2010-09-23 |
| 20100239481 | PROCESS FOR TRITIUM REMOVAL FROM WATER BY TRANSFER OF TRITIUM FROM WATER TO AN ELEMENTAL HYDROGEN STREAM, FOLLOWED BY MEMBRANE DIFFUSION TRITIUM STRIPPING AND ENRICHMENT, AND FINAL TRITIUM ENRICHMENT BY THERMAL DIFFUSION - A diffusion based process for tritium removal from water by tritium transfer from water to an elemental hydrogen stream, followed by a membrane diffusion cascade for tritium stripping and enrichment, and final tritium enrichment by one or more thermal diffusion columns. The combination of process steps takes advantage of membrane diffusion's large throughput capability at low tritium concentration with the simplicity of thermal diffusion for small throughput final tritium enrichment. The membrane diffusion stages use supported or unsupported microporous or hydrogen permeable metal membranes (such as Pd/Ag alloy). The diffusion process is compatible with any front-end process to transfer tritium from tritiated water to elemental hydrogen. The process may be designed and operated at low pressure, with small gas inventory, and no inherent overpressure hazard. | 2010-09-23 |
| 20100239482 | METHOD OF PRODUCING GAS BARRIER LAYER, GAS BARRIER FILM FOR SOLAR BATTERIES AND GAS BARRIER FILM FOR DISPLAYS - A method according to the invention comprises: starting plasma discharge for forming the gas barrier layer in a film deposition chamber; and producing the gas barrier layer by using a plasma after a first predetermined period of time has elapsed from a start of the plasma discharge. | 2010-09-23 |
| 20100239483 | Diamond-Bonded Bodies and Compacts with Improved Thermal Stability and Mechanical Strength - Thermally stable diamond-bonded compacts include a diamond-bonded body having a thermally stable region extending a distance below a diamond-bonded body surface. The thermally stable region comprises a matrix first phase of bonded together diamond crystals, and a second phase interposed within the matrix phase. At least some population of the second phase comprises a reaction product formed between an infiltrant material and the diamond crystals at high pressure/high temperature conditions. The diamond bonded body further includes a polycrystalline diamond region that extends a depth from the thermally stable region and has a microstructure comprising a polycrystalline diamond matrix phase and a catalyst material disposed within interstitial regions of the matrix phase. The compact includes a substrate attached to the diamond-bonded body. | 2010-09-23 |
| 20100239484 | Method for Refining Solar Grade (SoG) Silicon by Using Physical Metallurgy - The present invention discloses a method for physically refining solar grade silicon comprises: firstly, by using a vacuum induction furnace, selecting a high oxidizing crucible to avoid carbon pollution; secondly, conducting the vacuum-pumping during the heating process; thirdly, injecting a protective gas, after the smelting temperature reaches a predetermined temperature, the powerful oxidizing gas (chlorine) is injected into the bottom of the crucible; fourthly, producing chemical reaction with the powerful oxidizing gas and impurity such as Fe—Al—Ca—P—V, so that the reaction resultant is gasified, while the power oxidizing gas stirs with the metallic silicon liquation, and preserving the temperature; fifthly, injecting the refined metallic silicon into a pouring box to enter into a oriented crystallization procedure. The present invention has following advantages: being easy and convenient to be implemented, rapid heating, no pollution, and the purity of the silicon material refined by using the method in the present invention can be graded to 5N or more. | 2010-09-23 |
| 20100239485 | METHOD OF MANUFACTURING FLUORINATED GAS COMPOUNDS AND APPARATUS FOR MANUFACTURING THE SAME - An apparatus of generating fluorinated gas compounds by means of reacting liquid stock with gaseous material is characterized by providing a circulating system comprised of a reaction chamber where a liquid mixture containing the liquid stock reacts with the gaseous material, a fluid conduit through which the liquid mixture alone flows, an upper fluid channel through which the reacted liquid mixture moves from the top of the reaction chamber to the top of the fluid conduit, and a lower fluid channel through which the liquid mixture moves from the bottom of the fluid conduit to the bottom of the reaction chamber, and sparging into the bottom of the reaction chamber (A) the virgin gaseous material and (B) at least one selected from the fluorinated gas compounds resulted from the reaction in the reaction chamber, including the first fluorinated gas product generated in the first cycle of the reaction and the second or later gas product resulted from further fluorinating the first or later gas product in the succeeding cycle, so as to circulate the liquid mixture. | 2010-09-23 |
| 20100239486 | Method for making carbon composite material - A method for making a carbon composite material, the method including providing a 1,4-benzenedicarboxylate-metal complex in a vessel, putting the vessel carrying the 1,4-benzenedicarboxylate-metal complex into an environment with a protective gas therein, and heating the 1,4-benzenedicarboxylate-metal complex to a temperature in a range from about 500° C. to about 1300° C. | 2010-09-23 |
| 20100239487 | NON-CEMENTITIOUS COMPOSITIONS COMPRISING CO2 SEQUESTERING ADDITIVES - Non-cementitious CO | 2010-09-23 |
| 20100239488 | Controlled Placement and Orientation of Nanostructures - A method for controlled deposition and orientation of molecular sized nanoelectromechanical systems (NEMS) on substrates is disclosed. The method comprised: forming a thin layer of polymer coating on a substrate; exposing a selected portion of the thin layer of polymer to alter a selected portion of the thin layer of polymer; forming a suspension of nanostructures in a solvent, wherein the solvent suspends the nanostructures and activates the nanostructures in the solvent for deposition; and flowing a suspension of nanostructures across the layer of polymer in a flow direction; thereby: depositing a nanostructure in the suspension of nanostructures only to the selected portion of the thin layer of polymer coating on the substrate to form a deposited nanostructure oriented in the flow direction. By selectively employing portions of the method above, complex NEMS may be built of simpler NEMSs components. | 2010-09-23 |
| 20100239489 | Methods for Controlling the Quality of Metal Nanocatalyst for Growing High Yield Carbon Nanotubes - Methods are provided for the preparation of single-walled carbon nanotubes using chemical vapor deposition processes. In some aspects, single-walled carbon nanotubes having narrow distribution of diameters are formed by contacting a carbon precursor gas with a catalyst on a support, wherein the catalyst has an average diameter of less than about 2 nm. | 2010-09-23 |
| 20100239490 | Processes for growing carbon nanotubes using disordered carbon target - Processes for producing single-wall carbon nanotubes without catalysts are provided. The nanotubes are produced by vaporizing silicon carbide and carbon. | 2010-09-23 |
| 20100239491 | Method of producing carbon nanotubes - The present teachings are directed to methods of preparing cylindrical carbon structures, specifically single-walled carbon nanotubes, with a desired chirality. The methods include the steps of providing a catalyst component on a substrate and a carbon component, contacting the catalyst component and the carbon component to produce a cylindrical carbon structure. Then, no longer providing the carbon component and determining the chirality of the cylindrical carbon structure. The catalyst component is then cleaned and the process is repeated until the cylindrical carbon structure fulfills a desired characteristic, such as, length. The chirality of the single-walled carbon nanotube grown, after cleaning of the catalyst component, has the same chirality as the initially produced nanotube. | 2010-09-23 |
| 20100239492 | Method and system for manufacturing carbon black - A method of manufacturing carbon black comprising the steps of mixing waste tire material and waste plastic in a pressure vessel, charging the pressure vessel with an inert gas to a desired pressure control range, controllably heating the pressure vessel to increase temperature inside the vessel until the temperature reaches a desired temperature control range, while maintaining pressure within the pressure control range, and maintaining temperature and pressure within the respective control ranges for a desired soak time while venting gases generated in the pressure vessel, wherein substantially pure carbon black is produced, is disclosed. | 2010-09-23 |
| 20100239493 | METHODS AND COMPOUNDS FOR FORMING MONOLITHIC TITANIA, OPTIONALLY BIOMOLECULE DOPED, WITH CONTROLLED MORPHOLOGY USING BIOCOMPATIBLE SOL-GEL PROCESSES - The present invention includes polyol modified titanium compounds, their preparation and use in methods to make biomolecule compatible monolithic titania. The invention also includes the use of the biomolecule compatible monolithic titania in bioanalytic applications, for example in biosensors, chromatographic columns, microarrays and bioaffinity columns. | 2010-09-23 |
| 20100239494 | Method for Producing Hydrogen Using Block Copolymer and Oxidation Reaction of Metals - The present inventions are a method for production of hydrogen which decomposes water into hydrogen by oxidation of metals only when the metals are exposed to the water, while preventing oxidation of pure metal nanoparticles using block copolymers and, in addition, hydrogen produced by the method described above. The method of the present invention has advantages of improved convenience and simplicity, achieves a preferable approach for hydrogen storage because the metal nanoparticles enclosed by the block copolymer have the ease of delivery and reaction thereof. Additionally, the method of the present invention only using water and the metal is considered eco-friendly and useful in industrial energy applications. | 2010-09-23 |
| 20100239495 | Hydride composite and preparation process of hydrogen gas - The present invention is: a hydride composite containing NaH and a metal salt containing an alkali earth metal or a transition metal; and a preparation process of a hydrogen gas including a reaction process to react such a hydride composite with an ammonia gas. Further, the present invention is: a hydride composite containing NaH, a metal salt containing an alkali earth metal or a transition metal, and an ammonia source that is a solid at ordinary temperatures and generates an ammonia gas by decomposition; and a preparation process of a hydrogen gas including a reaction process to heat such a hydride composite. | 2010-09-23 |
| 20100239496 | Imaging agents for detecting neurological disorders - Imaging agents of formula (I) and methods for detecting neurological disorders comprising administering to a patient in need compounds of formula (I) capable of binding to tau proteins and β-amyloid peptides are presented herein. The invention also relates to methods of imaging Aβ and tau aggregates comprising introducing a detectable quantity of pharmaceutical formulation comprising a radiolabeled compound of formula (I) and detecting the labeled compound associated with amyloid deposits and/or tau proteins in a patient. These methods and compositions enable preclinical diagnosis and monitoring progression of AD and other neurological disorders. | 2010-09-23 |
| 20100239497 | OXIDIZED AVIDIN WITH HIGH RESIDENCY TIME IN THE TREATED TISSUES - The present invention describes chemically modified avidins that have higher permanence in treated tissues compared to wild type avidin. Avidin oxidation is performed by periodate incubation in the presence of the low affinity ligand HABA which, occupying the biotin binding sites, prevents protein denaturation during the oxidation step. Periodate oxidation generates CHO groups from avidin mannose ring opening that, once injected, react with tissue NH | 2010-09-23 |
| 20100239498 | METHOD OF MAINTAINING THE FUNCTION OF LIVER TISSUE CELLS OVER LONG TIME - The function of liver tissue cells can be maintained over a long period of time by culturing the liver tissue cells on a cell culture support, which is coated with a polymer showing a change in the hydration force in the temperature range of from 0 to 80° C., within the temperature range wherein the polymer has a small hydration force, then changing the temperature of the liquid culture medium to a level at which the polymer shows a large hydration force, thus stripping off the liver tissue cells having been cultured, and transplanting the thus obtained liver tissue cells into a definite site in vivo. | 2010-09-23 |
| 20100239499 | Methods and compositions for genetic and retinal disease - An inventive method for treatment or prevention of vascular diseases of the retina is provided. A Norrin compound is optionally administered to a subject either directly and/or as expressed by a cell. The presence of the compound is either protective of or therapeutic for a pathological condition of the retina. Preferred pathological conditions are those linked to the absence of or mutation of norrin protein and are preferably Norrie disease, FEVR, or macular degeneration. | 2010-09-23 |
| 20100239500 | SUBSTITUTED TRIAZINE COMPOUNDS FOR NERVE REGENERATION - A family of substituted triazine compounds is synthesized by combinatorial solid phase chemistry. These compounds were found to increase the growth of neurons/axons from central nervous system neurons that had been damaged, and can be used in methods and pharmaceutical compositions for treating injuries, diseases and conditions associated with nerve damage. | 2010-09-23 |
| 20100239501 | GENE SENSITIVE TO BONE/JOINT DISEASE AND USE THEREOF - The present invention provides a suppressing agent for inflammatory cytokine expression in joints and/or joint destruction (e.g., articular cartilage destruction) and/or pain in a bone/joint disease, comprising a substance that suppresses the expression or activity of a protein comprising the same or substantially the same amino acid sequence as the amino acid sequence shown by SEQ ID NO:2, a screening method for a substance that regulates inflammatory cytokine expression in joints and/or joint destruction (e.g., articular cartilage destruction) and/or pain in a bone/joint disease, comprising using the protein or a partial peptide thereof, and a diagnostic method for genetic susceptibility to a bone/joint disease, comprising detecting a polymorph in the base shown by base number 24007 in the partial base sequence of the human EDG2 gene shown by SEQ ID NO:3. | 2010-09-23 |
| 20100239502 | IN VIVO EXPRESSION ANALYSIS USING ULTRASOUND-INDUCED TRANSFECTION OF REPORTER CONSTRUCTS - The invention features compositions and methods for in vivo expression analysis. The data presented herein demonstrates that ultrasound-enhanced delivery and/or expression of a composition for expression analysis comprising microbubbles vectors as well as a genetic payload, comprising a “always-on” promoter, a “reference” reporter gene, a “query” promoter and an “answer” reporter gene, enables in vivo analysis of gene expression both without requiring prior preparation (especially genetic modification) of the test subject (animal or patient) and without causing long term or systemic effects on the subject. Such an invention can be used, for example, to query the epigenotypic or phenotypic response of the individual subject to a foreign effector substance such as a pyrogen, pharmaceutical compound, pharmaceutical lead compound, an allergen, an autoimmunogene, a toxin, a polyclonal antibody, a monoclonal antibody, an antigen, a lipid, a carbohydrate, a peptide, a protein, a protein-complex, an amino acid, a fatty acid, a nucleotide, DNA, RNA, PNA, siRNA and micro RNA. | 2010-09-23 |
| 20100239503 | CALCIUM-BINDING AGENTS INDUCE HAIR GROWTH AND/OR NAIL GROWTH - This invention provides novel methods for inducing hair growth and/or inhibiting hair loss and/or inducing nail growth in a mammal. In various embodiments the methods involve administering, e.g., to a mammal in need thereof, a calcium-binding peptide and/or peptide-like moiety in an amount sufficient to induce hair growth and/or to inhibit hair loss. In certain embodiments the agent is topically and/or transdermally administered. | 2010-09-23 |
| 20100239504 | IMAGING NUCLEIC ACID BINDING PROTEINS - Reporter conjugates for non-invasive in vivo detection, e.g., imaging, of expression or activity of nucleic acid binding proteins are disclosed. The conjugates include a targeting nucleic acid linked to a reporter group, e.g., a contrast agent, such as a paramagnetic label that can be used with magnetic resonance imaging. The targeting nucleic acid can be a double-stranded nucleic acid that binds to the nucleic acid binding protein the expression of which is to be imaged. In some embodiments, the contrast agent is a chelated metal such as gadolinium or dysprosium. The invention also features methods to image protein expression in various tissues, including the brain, and therapeutic methods. | 2010-09-23 |
| 20100239505 | APPARATUS WITH AN ECHOGENIC COATING AND ECHOGENIC LAYER - An apparatus having an echogenic coating of a polymer with hollow spaces present in the polymer. In order to achieve an echogenicity that supplies largely isotropic ultrasonic echo images, the hollow spaces should be microhollow spheres embedded in the polymer. | 2010-09-23 |
| 20100239506 | METHODS FOR DETECTION AND DETERMINATION OF VITAMIN C BY LUMINESCENCE - The present invention provides a method for detection or determination of vitamin C by luminescence that employs a redox-responsive fluorogenic probe consisting of porphyrin or phthalocyanine with a nitroxide radical(s), or that employs a liposome preparation comprising the said redox-responsive fluorogenic probe. The present method can overcome the problems of prior art methods, and in particular, are applicable for bioimaging to allow elucidation of the behavior of vitamin C in vivo. | 2010-09-23 |
| 20100239507 | SURFACE MODIFIED AEROSOL PARTICLES, A METHOD AND APPARATUS FOR PRODUCTION THEREOF AND POWDERS AND DISPERSIONS CONTAINING SAID PARTICLES - A method and apparatus for multicomponent surface modified aerosol particle production suitable for, for instance, therapeutic, cosmetic or diagnostic use in which an aerosol containing an active agent is introduced in an aerosol reactor together with a surface agent or surface agent source and/or precursor and wherein the surface agent and/or surface agent precursor is volatilizable. The surface agent vapor saturation ratio is elevated so to cause it to nucleate from the gas phase. Reactor conditions are maintaining such that the active agent remains in the condensed phase and provides a surface for the surface agent to deposit on the active agent containing aerosol particle thus producing surface modified aerosol particles. The method can be used for batch or continuous production. Particles made according to the method and powders and dispersions containing the particles are also described. | 2010-09-23 |
| 20100239508 | ULTRAVIOLET ABSORBER - There is provided an ultraviolet absorber having a strong absorptive capacity in the UVA range and an absorptive capacity in the UVB range to have an ultraviolet inhibitory effect in a wide range of wavelength, increasing in an ultraviolet absorptive capacity over the course of ultraviolet irradiation time in both the UVA and the UVB ranges and having an excellent solubility. An ultraviolet absorber comprising, as an active ingredient, a compound of General Formula I: | 2010-09-23 |
| 20100239509 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS - The present patent application relates to a cosmetic or dermatological composition comprising, in a cosmetically or dermatologically acceptable medium, a polymer comprising:
| 2010-09-23 |
| 20100239510 | SKIN-CARE COMPOSITION COMPRISING DILL EXTRACT - A skin-care composition may comprise a dill extract, a safe and effective amount of a peptide, a safe and effective amount of a hydrating skin active, and a dermatologically acceptable carrier. The skin-care composition may further comprise a safe and effective amount of an acute skin-care active. Further, a method of producing a chronic skin-firming benefit and, optionally, an acute skin-tightening sensation, said method comprising the step of topically applying to the skin of a mammal in need of such treatment, a safe and effective amount of the skin-care composition. | 2010-09-23 |
| 20100239511 | SPHERICAL CALCIUM CARBONATE AND METHOD OF PRODUCING THE SAME - When spherical calcium carbonate is produced by blowing a carbon dioxide gas or a carbon dioxide-containing gas into an aqueous suspension containing calcium hydroxide to react them, after start of the reaction, an aqueous solution or suspension of a water-soluble phosphoric acid compound or a water-soluble salt thereof is added to the reaction mixture when carbonation ratio reaches 2 to 10%, and the reaction is further allowed to continue at a low gas blowing rate of 1.0 NL/minute or lower (step (a)). Subsequently, an aqueous suspension containing calcium hydroxide and an aqueous solution or suspension of a water-soluble phosphoric acid compound or a water-soluble salt thereof are added to the reaction mixture, and a carbon dioxide gas or a carbon dioxide-containing gas is introduced to allow to react and thereby produce spherical calcium carbonate having a mean particle diameter of 10 μm or larger. This production method is performed under high velocity revolution from the start of the reaction to the end of the step (a). This method provides calcite type spherical calcium carbonate showing high brightness and small friction coefficient, and having a shape comparatively close to a true sphere and a mean particle diameter of 10 μm or larger. | 2010-09-23 |
| 20100239512 | ADSORPTION AND RELEASE OF NITRIC OXIDE IN METAL ORGANIC FRAMEWORKS - Disclosed are metal organic frameworks that adsorb nitric oxide, NO-loaded metal organic frameworks, methods of preparing the NO-loaded metal organic frameworks, methods of releasing the nitric oxide into a solution or into air, and uses of the metal organic frameworks. | 2010-09-23 |
| 20100239513 | AQUEOUS COMPOSITIONS COMPRISING VESICLES HAVING CERTAIN VESICLE PERMEABILITY - Compositions for effectively delivering a water-soluble active material to a surface comprise:
| 2010-09-23 |
| 20100239514 | COMPOSITIONS AND METHODS FOR USE ON ARTIFICIALLY COLORED HAIR - The present invention provides a cosmetic composition comprising at least one saccharide-siloxane copolymer, a cosmetically-acceptable medium, and optionally, at least one auxiliary agent chosen from a nonionic agent and a cationic agent, wherein the pH of the composition is up to about 5.8. The present invention also provides for a method of using said composition for enhancing color protection of artificially colored hair while providing color vibrancy, excellent conditioning, natural feel and brilliant shine. | 2010-09-23 |
| 20100239515 | COSMETIC COMPOSITION CONTAINING A GLYCINE COMPOUND - Composition useful for coating the eyelashes containing an aqueous phase and an emulsifying system including at least one glycine derivative and/or a salt thereof. | 2010-09-23 |
| 20100239516 | Poly cationic compounds - The present invention relates to a novel class of polymeric compounds having specific quaternized amine based upon a dimer acid reacted with a combination of a monohydroxy functional amine and a specific di-hydroxy functional tertiary alkanolamine, to make an ester tertiary amine, which is a subsequent step is converted to a quaternary compound. Dimer acid is a C-36 diacid having a cyclic structure and reacting it with the two type of amine groups allow for the synthesis of a high molecular weight cationic compound which is extremely substantitive to human skin and are well tolerated by human tissue making them suitable for use preparation of barrier products for personal care applications. These materials are dimethylaminopropyl amine free, which is highly desirable in personal care applications. | 2010-09-23 |
| 20100239517 | NOVEL CONJUGATED PROTEINS AND PEPTIDES - The invention provides a novel process for conjugating a polymer, especially PEG, to a protein or peptide, which comprises reacting a polymeric conjugation reagent with a protein or peptide containing a polyhistidine tag under conditions such that conjugation occurs via said polyhistidine tag. The resulting conjugates are novel. The invention further relates to novel conjugates of the general formula (I) in which one of X and X′ represents a polymer, and the other represents a hydrogen atom; each Q independently represents a linking group; W represents an electron-withdrawing moiety or a moiety preparable by reduction of an electron-withdrawing moiety; or, if X′ represents a polymer, X-Q-W— together may represent an electron withdrawing group; and in addition, if X represents a polymer, X′ and electron withdrawing group W together with the interjacent atoms may form a ring; Z represents a protein or a peptide linked to A and B via respective histidine residues; A is a C | 2010-09-23 |
| 20100239518 | OPHTHALMIC COMPOSITION - The present invention provides an ophthalmic composition which stabilizes the tear film during wearing contact lens, prevents eye dryness, imparts a favorable sensation in using, is highly convenient with no risk of misuse and shows a high efficiency in the course from manufacturing to sales. More specifically, the present invention provides a wetting solution—eye drops for contact lenses comprising (A) one or more member (s) selected from the group consisting of a cellulose-based polymer, a vinyl-based polymer, polyethylene glycol and dextran; and (B) a terpenoid. | 2010-09-23 |
| 20100239519 | Foam Stabilizer Composition - This invention provides a composition for sterilization comprising povidone iodine in which by improving the persistence and stability of foam, the composition for sterilization is capable of preventing dripping in use as well as of achieving reliable disinfection and sterilization. The composition for sterilization in this invention is capable of forming stable and persistent foam as well as of achieving effective disinfection and sterilization by blending a specific amount of a sulfate type surfactant therein. | 2010-09-23 |
| 20100239520 | ORGANIC COMPOUNDS - The present invention provides heterocyclic derivatives that modulate the activity of stearoyl-CoA desaturase. Methods of using such derivatives to modulate the activity of stearoyl-CoA desaturase and pharmaceutical compositions comprising such derivatives are also encompassed. | 2010-09-23 |
| 20100239521 | METHOD FOR THE PREPARATION OF MICRO- AND NANO-SIZED CARRIER SYSTEMS FOR THE ENCAPSULATION OF BIOACTIVE SUBSTANCES - The various embodiments herein provide a method for producing a carrier system for the encapsulation or entrapment of a bioactive agent. According to one embodiment herein, producing a carrier complex of a bioactive ingredient disposed within a carrier material, the method comprising the steps of: (a) providing a complexation zone supplied with an aqueous medium containing the carrier material; (b) simultaneously stirring and heating the aqueous medium; (c) adding the bioactive ingredient to the aqueous medium and maintaining the complexation zone under conditions of temperature effective to facilitate complexation of the bioactive ingredient by the carrier material; and (d) recovering from the complexation zone a carrier complex of the bioactive ingredient. | 2010-09-23 |
| 20100239522 | CHEMOTHERAPEUTIC FOR INDUCING AN MSH2-DEPENDENT APOPTOTIC PATHWAY - A method of treating cancer in a subject in need thereof comprises administering said subject reserpine, yohimbine, an analog thereof, or a pharmaceutically acceptable salt or prodrug thereof, in an amount effective to treat the cancer. Compounds and compositions useful for carrying out the method are also described. | 2010-09-23 |
| 20100239523 | TLR MODULATORS AND METHODS FOR USING THE SAME - The invention provides Toll-like receptor (TLR) modulators, compositions comprising the same, and methods for using the same. | 2010-09-23 |
| 20100239524 | MICROPARTICLES PREPARED USING AN IONIC LIQUID - Microparticles comprising at least one active agent embedded within a biocompatible, biodegradable polymeric matrix, wherein said microparticles are prepared with an ionic liquid. | 2010-09-23 |
| 20100239525 | SUBSTITUTED 5,6-DIHYDRO-6-PHENYLBENZO[F]ISOQUINOLIN-2-AMINE COMPOUNDS - The present invention relates to substituted 5,6-dihydro-6-phenylbenzo[f]isoquinolin-2-amine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted 5,6-dihydro-6-phenylbenzo[f]isoquinolin-2-amine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof. | 2010-09-23 |
| 20100239526 | SUBSTITUTED IMIDAZOLYL-5,6-DIHYDROBENZO[N]ISOQUINOLINE COMPOUNDS - The present invention relates to substituted imidazolyl-5,6-dihydrobenzo[n]isoquinoline compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted imidazolyl-5,6-dihydrobenzo[n]isoquinoline compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof. | 2010-09-23 |
| 20100239527 | 2,3-SUBSTITUTED AZAINDOLE DERIVATIVES FOR TREATING VIRAL INFECTIONS - The present invention relates to 2,3-Substituted Azaindole Derivatives, compositions comprising at least one 2,3 -Substituted Azaindole Derivatives, and methods of using the 2,3-Substituted Azaindole Derivatives for treating or preventing a viral infection or a virus-related disorder in a patient. | 2010-09-23 |
| 20100239528 | Treating or Ameliorating a Neuroinflammatory or Demyelinating Disorder with Prolactin and Interferon-Beta - Methods, compositions and kits for treating or ameliorating a disorder associated with neuroinflammation or de-myelination in a mammal are disclosed. Said methods, compositions and kits comprise prolactin, a prolactin-inducing agent, or a variant, analog or functional fragment of prolactin in combination with interferon-β. | 2010-09-23 |
| 20100239529 | PEG-Interferon-Beta Formulations - The invention relates to a liquid pharmaceutical composition comprising a pegylated IFN-β (PEG-IFN-β), an excipient, a surfactant and a buffer wherein said excipient is a polyol, wherein said surfactant is a non-ionic surfactant and wherein said buffer is a sodium acetate buffer. | 2010-09-23 |
| 20100239530 | IFNAR2 MUTANTS, THEIR PRODUCTION AND USE - The present invention relates to mutant polypeptides of the beta chain of the type I IFN receptor (IFNAR2 mutant) with enhanced affinity for IFNβ as compared to the wild type protein for prolonging the effect of IFNβ in vivo. | 2010-09-23 |
| 20100239531 | STABLE LIQUID INTERFERON FORMULATIONS - Liquid interferon compositions having a pH between 4.0 and 7.2 are described. The compositions comprise interferon-beta and a stabilizing agent at between about 0.3% and 5% by weight which is an amino acid selected from the group consisting of acidic amino acids, arginine and glycine. If needed, salt is added to provide sufficient ionic strength. The liquid composition has not been previously lyophilized or previously cavitated. The liquid is preferably contained within a vessel having at least one surface in contract with the liquid that is coated with a material inert to adsorption of interferon-beta. A kit for parenteral administration of a liquid interferon formulation and a method for stabilizing liquid interferon compositions are also described. | 2010-09-23 |
| 20100239532 | INTERFERON ALPHA2A MODIFIED BY POLYETHYLENE GLYCOL, THE PREPARATION AND USE THEREOF - The present invention relates to interferon (IFN)-α2a modified at a specific Lys residue with Y-shaped branched polyethylene glycol (PEG) derivative and the preparation thereof, as well as the use of the prepared IFN-α2a modified by PEG at a single amino acid residue in medicines. | 2010-09-23 |
| 20100239533 | Thraustochytrids, Fatty Acid Compositions, and Methods of Making and Uses Thereof - The present invention is directed to isolated thraustochytrid microorganisms as well as strains and mutants thereof. The invention is further directed to biomasses, microbial oils, compositions, cultures, methods of producing microbial oils, and methods of using the isolated thraustochytrids, biomasses, and microbial oils. | 2010-09-23 |
| 20100239534 | Hybrid proteins that migrate retrogradely and transynaptically into the CNS - The non-toxic proteolytic C fragment of tetanus toxin (TTC peptide) has the same ability to bind nerve cells and be retrogradely transported through a synapse as the native toxin. A hybrid protein encoded by the IacZ-TTC gene fusion retains the biological functions of both proteins in vivo, i.e. retrograde transynaptic transport of the TTC fragment and β-gal enzymatic activity. After intramuscular injection, enzymatic activity could be detected in motoneurons and connected neurons of the brainstem areas. This strategy is useful for the delivery of a biological activity to neurons from the periphery to the central nervous system. Such a hybrid protein can also be used to map synaptic connections between neural cells. | 2010-09-23 |
| 20100239535 | METHOD FOR ISOLATING HOMOGENEOUS POPULATIONS OF TRANSDUCED PROGENITORS STABLY EXPRESSING SPECIFIC LEVELS OF A TRANSGENE - The invention is directed to a method for producing precursor cells expressing a target gene, for example VEGF, at desired levels comprising stably transducing precursor cells with the target gene linked to a cell-surface marker gene, for example truncated CD8/CD8 | 2010-09-23 |
| 20100239536 | Modified Bacteriophage Including an Alpha/Beta Small Acid-Soluble Spore Protein (SASP) Gene - Provided is a modified bacteriophage capable of infecting a target bacterium, which bacteriophage includes an α/β small acid-soluble spore protein (SASP) gene encoding a SASP which is toxic to the target bacterium, wherein the SASP gene is under the control of a constitutive promoter which is foreign to the bacteriophage and the SASP gene. | 2010-09-23 |
| 20100239537 | BACTERIAL ISOLATE AND METHODS FOR DETOXIFICATION OF TRICHOTHECENE MYCOTOXINS - The invention provides a bacterial isolate defined by accession number 180507-1 filed with the International Depository Authority of Canada. The bacteria are capable of degrading trichothecene mycotoxins. Also provided are compositions comprising the bacteria and methods of preventing or treating food, foodstuffs, crops and harvested crops that are contaminated or susceptible to contamination with trichothecene mycotoxins. Kits are also provided. | 2010-09-23 |
| 20100239538 | COMPOSITIONS COMPRISING VASCULAR AND MYOCYTE PROGENITOR CELLS AND METHODS OF THEIR USE - The invention provides compositions of adult cardiac vascular progenitor cells (VPCs) and adult cardiac myocyte progenitor cells (MPCs) useful for the treatment of various cardiac conditions. The invention also encompasses methods of generating a biological bypass, repairing damaged myocardium, and treating or preventing hypertensive cardiomyopathy and heart failure with the compositions of the invention. Methods of isolating the cardiac progenitor cells are also disclosed. | 2010-09-23 |
| 20100239539 | Methods for promoting differentiation and differentiation efficiency - The invention is directed to methods for promoting differentiation of stem cells to hematopoietic cell lineages. The invention is further directed to increasing the differentiation efficiency of hematopoietic stem/progenitor cells. Such methods utilize novel compositions, including but not limited to, Amnion-derived Multipotent Progenitor cells (herein referred to as AMP cells) and conditioned media derived therefrom (herein referred to as Amnion-derived Cellular Cytokine Solution or ACCS), each alone or in combination with each other or other agents. | 2010-09-23 |
| 20100239540 | Peptide Linked Cell Matrix Materials for Stem Cells and Methods of Using the Same - Biostructures that comprises modified alginates entrapping one or more stem cells are discloses. The modified alginates comprise at least one alginate chain section to which is bonded by covalent bonding at least one cell attachment peptide. Pluralities of stem cells are also disclosed. Methods of preventing death of stem cells and cells differentiated there from are disclosed. Methods of preparing a plurality of stem cells are disclosed. Methods of treating an individual who has a degenerative disease, such as a neurological disorder, or injury involving nerve damage by administering stem cells to said individual are disclosed. | 2010-09-23 |
| 20100239541 | TRANSPLANTATION OF HUMAN NEURAL CELLS FOR TREATMENT OF NEURODEGENERATIVE CONDITIONS - A method of treating neurodegenerative conditions is provided. Neural stem cells may be implanted at and/or remote from a region of neuron degeneration. The methods can include isolating neural stem cells from regions where specific types of neurons corresponding to the neurons to be replaced are generated. The methods can include isolating neural stem cells secreting growth factors affecting the growth and/or regeneration of specific types of neuron. In this invention, we disclose a method of treating such disorders, including several neurodegenerative disorders arising from the lack of cells that produce particular neurotransmitters in neural circuitry by transplanting exogenously cultured and expanded neural progenitors which, upon transplantation into a neural tissue, differentiate into neurons capable of integrating and producing neurotransmitters in sufficient quantities and in a sufficient manner to overcome the symptoms associated with the neurodegeneration. | 2010-09-23 |
| 20100239542 | PLURIPOTENT EMBRYONIC-LIKE STEM CELLS, COMPOSITIONS, METHODS AND USES THEREOF - The present invention relates to pluripotent stem cells, particularly to pluripotent embryonic-like stem cells. The invention further relates to methods of purifying pluripotent embryonic-like stem cells and to compositions, cultures and clones thereof. The present invention also relates to a method of transplanting the pluripotent stem cells of the present invention in a mammalian host, such as human, comprising introducing the stem cells, into the host. The invention further relates to methods of in vivo administration of a protein or gene of interest comprising transfecting a pluripotent stem cell with a construct comprising DNA which encodes a protein of interest and then introducing the stem cell into the host where the protein or gene of interest is expressed. The present also relates to methods of producing mesodermal, endodermal or ectodermal lineage-committed cells by culturing or transplantation of the pluripotent stem cells of the present invention. | 2010-09-23 |
| 20100239543 | PLURIPOTENT EMBRYONIC-LIKE STEM CELLS, COMPOSITIONS, METHODS AND USES THEREOF - The present invention relates to pluripotent stem cells, particularly to pluripotent embryonic-like stem cells. The invention further relates to methods of purifying pluripotent embryonic-like stem cells and to compositions, cultures and clones thereof. The present invention also relates to a method of transplanting the pluripotent stem cells of the present invention in a mammalian host, such as human, comprising introducing the stem cells, into the host. The invention further relates to methods of in vivo administration of a protein or gene of interest comprising transfecting a pluripotent stem cell with a construct comprising DNA which encodes a protein of interest and then introducing the stem cell into the host where the protein or gene of interest is expressed. The present also relates to methods of producing mesodermal, endodermal or ectodermal lineage-committed cells by culturing or transplantation of the pluripotent stem cells of the present invention. | 2010-09-23 |
| 20100239544 | METHODS OF TREATMENT USING ELECTROMAGNETIC FIELD STIMULATED STEM CELLS - Methods of modifying stem cells and compositions of modified stem cells, in particular mesenchymal stem cells, using electric or electromagnetic fields. In various embodiments, the present invention's methods are for the treatment of a human or other mammal subject in need thereof, comprising providing an in vitro culture comprising mesenchymal stem cells, administering an electric stimulation to the in vitro culture, and implanting the mesenchymal stem cells into the subject. Methods also include treatment of a human or other mammal subject, comprising implanting mesenchymal stem cells into the subject, and administering an electric stimulation to the mesenchymal stem cells in situ. Other embodiments include methods of administering electric stimulation in conjunction with growth factors to stem cells. | 2010-09-23 |
| 20100239545 | Methods of expressing LIM mineralization protein in non-osseous cells - Methods of expressing LIM mineralization protein in non-osseous mammalian cells, such as stem cells or intervertebral disc cells (e.g., cells of the annulus fibrosus, or cells of the nucleus pulposus) are described. The methods involve transfecting the cells with an isolated nucleic acid comprising a nucleotide sequence encoding a LIM mineralization protein operably linked to a promoter. Transfection may be accomplished ex vivo or in vivo by direct injection of virus or naked DNA, or by a nonviral vector such as a plasmid. Expression of the LIM mineralization protein can stimulate proteoglycan and/or collagen production in cells capable of producing proteoglycyan and/or collagen. Methods for treating disc disease associated with trauma or disc degeneration are also described. | 2010-09-23 |
| 20100239546 | BACTERIAL MEDIATED TNF ALPHA GENE SILENCING - Methods are described for the delivery of one or more small interfering RNAs (siRNAs) to a eukaryotic cell using a bacterium. Methods are also described for using this bacterium to regulate gene expression in eukaryotic cells using RNA interference, and methods for treating an inflammatory disease or disorder. The bacterium includes one or more siRNAs or one or more DNA molecules encoding one or more siRNAs. Vectors are also described for use with the bacteria of the invention for causing RNA interference in eukaryotic cells. | 2010-09-23 |
| 20100239547 | SYNTHETIC HLA BINDING PEPTIDE ANALOGUES AND USES THEREOF - The present invention is directed to a synthetic peptide comprising a sequence of amino acids containing at least a segment that is an analogue of a native peptide that specifically binds to HLA A0201 or HLA A0301 molecules on a cell characteristic of a pathophysiologic state in a mammal. The synthetic peptide may be derived form native peptides comprising a breakpoint region of the WT1 protein. | 2010-09-23 |
| 20100239548 | Isolation and Identification of T Cells - The present invention relates to improved autologous T cell vaccines and improved methods for their production. The invention is also directed to methods for treating autoimmune diseases such as multiple sclerosis or rheumatoid arthritis using autologous T cell vaccines. The invention further directed to the diagnosis of T associated diseases. | 2010-09-23 |
| 20100239549 | ALPHA LIPOIC ACID CAPSULE COMPOSITION STABILIZED IN WATER PHASE AND METHOD FOR PREPARING THE SAME - The present invention relates to an alpha lipoic acid capsule composition stabilized in aqueous phase, which can effectively prevent alpha lipoic acid from decomposing due to external environmental conditions, such as water, temperature, light, and the like, and can maintain the stability of alpha lipoic acid from the interaction between the lipoic acid and other materials, which are added together with the lipoic acid when the lipoic acid is applied to cosmetics, foods, or medical supplies, by mixing water-dispersed alpha lipoic acid, a water-insoluble polymer having self-emulsification properties, and a hydrophilic solvent, thus capsulating alpha lipoic acid, and to a method of preparing the same. | 2010-09-23 |
| 20100239550 | MUTANT CyaA POLYPEPTIDES AND POLYPEPTIDE DERIVATIVES SUITABLE FOR THE DELIVERY OF IMMUNOGENIC MOLECULES INTO A CELL - The invention relates to mutant CyaA/E570Q+K860 polypeptides suitable for use as proteinaceous vectors for delivering one or more molecules of interest into a cell, in particular into a cell expressing the CD11b receptor. The invention further relates to polypeptide derivatives suitable for eliciting an immune response in a host. | 2010-09-23 |
| 20100239551 | COMPOUNDS AND COMPOSITIONS AS CHANNEL ACTIVATING PROTEASE INHIBITORS - The invention provides compounds and pharmaceutical compositions thereof, which are useful for modulating chan-nel activating proteases, and methods for using such compounds to treat, ameliorate or prevent a condition associated with a channel activating protease, including but not limited to prostasin, PRSS22, TMPRSS11 (e.g., TMPRSS11B, TMPRSSI1E), TMPRSS2, TMPRSS3, TMPRSS4 (MTSP-2), matriptase (MTSP-1), CAP2, CAP3, trypsin, cathepsin A, or neutrophil elastase. | 2010-09-23 |
| 20100239552 | Combination Therapies for Treating Metabolic Disorders - This invention is directed to pharmaceutical combinations comprising an antioxidant agent, an anti-inflammatory agent, and optionally at least one other anti-diabetic agent useful for treating metabolic disorders. This invention also encompasses pharmaceutically acceptable compositions comprising an antioxidant agent, an anti-inflammatory agent, optionally at least one other anti-diabetic agent, and at least one pharmaceutically acceptable carrier. The combinations and compositions of this invention are useful as methods for treating metabolic disorders including diabetes, particularly Type I and Type II diabetes, as well as diseases and disorders associated with diabetes, including but not limited to atherosclerosis, cardiovascular disease, inflammatory disorders, nephropathy, neuropathy, retinopathy, β-cell dysfunction, dyslipidemia, LADA, metabolic syndrome, hyperglycemia, insulin resistance, and/or chronic obstructive pulmonary disease in a mammal, particularly a diabetic mammal, and specifically a human patient. This invention is particularly directed to pharmaceutical compositions comprising an lipoic acid, one or more anti-inflammatories selected from the group consisting of diflunisal, diclofenac, dexibuprofen, dexketoprofen, naproxen, and salicylate, and optionally one or more pharmaceutically acceptable carriers. The compositions of this invention are useful as methods for treating metabolic disorders including type II diabetes, insulin resistance, beta-cell dysfunction, and hyperglycemia in a patient, particularly a diabetic patient. | 2010-09-23 |
| 20100239553 | METHODS FOR PROMOTING CELLULAR HEALTH AND TREATMENT OF CANCER - Systems and methods are provided herein that provide for promoting cellular health and treatment of cancer, and allied diseases such as diabetes and glaucoma. | 2010-09-23 |
| 20100239554 | EXTENDED RECOMBINANT POLYPEPTIDES AND COMPOSITIONS COMPRISING SAME - The present invention relates to compositions comprising biologically active proteins linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of glucose-related diseases, metabolic diseases, coagulation disorders, and growth hormone-related disorders and conditions. | 2010-09-23 |
| 20100239555 | Enzymatically active compositions for suppressing sulfide generation and methods of use thereof - The present invention provides an enzymatically active composition for suppressing sulfide generation. The composition is free from sulfur dehydrogenase and comprises at least one enzyme having sufficient sulfide-production inhibiting activity in an acidic medium to at least inhibit biogenic sulfide production, and an oxidized nitrogenous inorganic salt present in an amount sufficient to act as an electron acceptor for the enzyme. The oxidized nitrogenous inorganic salt preferably is selected from an alkali metal nitrite, an alkaline earth metal nitrite, an alkali metal nitrate, an alkaline earth metal nitrate, or a mixture of two or more of the foregoing salts. The enzymatically active composition is free from viable bacteria and is non-toxic (i.e., has an oral LD | 2010-09-23 |
| 20100239556 | PROMOTING ECM PRODUCTION BY FIBROBLAST CELLS AND/OR PROMOTING MIGRATION OF FIBROBLAST CELLS IN A BIOLOGICAL SYSTEM - The present invention relates to a method of promoting production of one or more components of extracellular matrix by one or more fibroblast cells in a biological system and/or promoting migration of one or more fibroblast cells in a biological system. The method includes exposing one or more fibroblast cells in the biological system to an effective amount of an agent with peroxidase activity. | 2010-09-23 |
| 20100239557 | COMPOSITIONS AND METHODS OF USING CHONDROITINASE ABCI MUTANTS - One aspect of the present invention relates to mutants of chondroitinase ABCI. Such chondroitinase ABCI mutants exhibit altered chondroitin lyase activity or increased resistance to inactivation from stressors including exposure to UV light or heat. Methods of using chondroitinase ABCI mutant enzymes are also provided. | 2010-09-23 |
| 20100239558 | Lipid Hydrolysis Therapy for Atherosclerosis and Related Diseases - The present invention comprises a method to diminish and/or eliminate atherosclerotic plaques, in mammals, through direct and indirect treatment of these plaques, in situ, using suitable substances which are capable of lipid removal, primarily through hydrolysis, either by a catalytic or stoichiometric process, wherein the substance targets receptors in and/or on the cell which lead to uptake into the lysosome. Such substances used to diminish and/or eliminate atherosclerotic plaques are generally comprised of lipid hydrolyzing proteins and/or polypeptides. | 2010-09-23 |
| 20100239559 | Novel nutritional food products for improved digestion and intestinal absorption - The present invention is directed to novel food products, e.g., nutritional food products and infant formula, which contain one ore more enzymes selected from lipase, protease, and amylase that have been formulated/stabilized to have sustained stability in an aqueous medium. Such formulations are intended to provide a greater degree of compliance based on their ability to be incorporated into aqueous media while avoiding unstable breakdown of the enzyme and large overdosing due to expected breakdown when exposed to an aqueous environment, including saliva. Further described in the invention are additives packaged with instructions for combination with an aqueous medium, and instructions for the administration of the resulting mixture to a subject. In certain embodiments, enzyme insufficient patients, e.g., infants and elderly persons, would find particular benefit from the food products described herein. | 2010-09-23 |
| 20100239560 | MULTI COMPONENT NON-WOVEN - The formation of a non-woven, free from organic solvent, formed through parallel formation of fibers on a collection device is disclosed. As the individual fibers are dry prior to contact with other fibers, the different contents of the various fiber types do not interact. However, when wetted, the fibers will start to be dissolved, or swell, and the different contents will be released and then interact. For the example of thrombin and fibrinogen, the interaction will initiate the formation of a fibrin coagulum by the cleavage of fibrinogen through the action of thrombin to form fibrin monomers that spontaneously polymerize to form a three dimensional network of fibrin. | 2010-09-23 |
