38th week of 2020 patent applcation highlights part 12 |
Patent application number | Title | Published |
20200289726 | Systems, Apparatuses, And Methods For Negative-Pressure Treatment With Pressure Delivery Indication - A dressing for treating a tissue site with negative pressure may include a core having a first surface, a second surface, and an absorbent between the first surface and the second surface, a cover disposed over the first surface of the core, a pressure indicator configured to change shape under negative pressure, and a fluid conductor coupling the pressure indicator to the second surface of the core. | 2020-09-17 |
20200289727 | WOUND DRESSING WITH NEGATIVE PRESSURE RETAINING VALVE - A wound dressing includes a cover layer, a tube, and a one-way valve. The cover layer is sealable to skin surrounding a wound site and includes a port extending through the cover layer. The tube includes a first end coupled to the cover layer via the port and a second end including an in-line connector configured to releasably attach the tube to a negative pressure source and detach the tube from the negative pressure source. The one-way valve is located along the tube between the first end and the second end and configured to allow fluid flow through the tube in a first direction from the first end to the second end and prevent fluid flow through the tube in a second direction from the second end to the first end. | 2020-09-17 |
20200289728 | Lyophilization Loading Tray Assembly and System - Provided is a loading tray assembly for housing a lyophilization container and a related system and method. The loading tray assembly includes a chassis including a contact void configured to facilitate direct contact between the attached lyophilization container and a lyophilizer shelf. The method includes securing a multi-part lyophilization container including a peelable seal on a lyophilization loading tray assembly, inputting a liquid into a non-breathable section of the lyophilization container, loading the tray assembly into a lyophilizer, freezing the liquid, applying heat energy and a vacuum, the vacuum causing an opening of the peelable seal and occluding the lyophilization container to isolate the frozen liquid. | 2020-09-17 |
20200289729 | EXPRESSION KIT - The present invention relates to an expression kit ( | 2020-09-17 |
20200289730 | METHOD OF MONITORING HEALTH CONDITIONS OF A PATIENT HAVING AN IMPLANTABLE BLOOD PUMP - A method of predicting an adverse event in a patient having an implantable blood pump including correlating a pulsatility value to a flow trough value associated with the blood pump to determine a flow peak value; dividing the determined flow peak value by a pump current to determine a pulsatility peak value; tracking a first moving average of the pulsatility peak value, the first moving average defining a threshold range; tracking a second moving average of the pulsatility peak value, the second moving average being faster than the first moving average; and generating an alert when the second moving average deviates from the threshold range. | 2020-09-17 |
20200289731 | SYSTEMS AND METHODS FOR CONTROLLING AN IMPLANTABLE BLOOD PUMP - Systems and methods for controlling an implantable pump are provided. For example, the exemplary controller for controlling the implantable pump may only rely on the actuator's current measurement. The controller is robust to pressure and flow changes inside the pump head, and allows fast change of pump's operation point. For example, the controller includes, a two stage, nonlinear position observer module based on a reduced order model of the electromagnetic actuator. The controller includes an algorithm that estimates the position of the moving component of the implantable pump based on the actuator's current measurement and adjusts operation of the pump accordingly. Alternatively, the controller may rely on position measurements and/or velocity estimations. | 2020-09-17 |
20200289732 | BLOOD PUMP FOR THE INVASIVE APPLICATION WITHIN A BODY OF A PATIENT - The invention relates to a blood pump for the invasive application within a body of a patient comprising a rotor which is drivable about an axis of rotation and is radially compressible or expandable and which has a hub and at least one impeller blade fastened thereto, as well as comprising a housing which is compressible or expandable in the radial direction by an axial stretching or axial compression. The object of making both the rotor and the housing expandable and compressible in as simple a manner as possible is achieved in accordance with the invention in that a control body is provided which passes through the hub in the longitudinal direction, which is freely axially displaceable relative to the hub and which is coupled to the housing on the distal side of the rotor such that it exerts pulling and/or compression forces on the housing by a movement in the longitudinal direction with respect to the housing. | 2020-09-17 |
20200289733 | Filtration System for Preparation of Fluids for Medical Applications - A system for filling multiple sterile containers includes a filter with an inlet port and multiple outlet ports, the outlet ports being pre-attached to sterile containers by respective filling lines of each container. Each container has an interior and each of the respective filling lines are connected to a respective container interior. The respective filling lines are sealed to the outlet ports and the containers such that the container interiors are isolated from an external environment except the inlet port, via the filter, forming a combined interior volume which is sterile. A container that is connectable to an outlet port the system has a bladder, a first tube and a second tube connected to the bladder, and a sterilizing filter. The container, the first tube and the second tube, and the sterilizing filter are sterile before water is flowed through the sterilizing filter into the bladder. | 2020-09-17 |
20200289734 | Sorbent Processing of Dialysate to Increase Solute Removal During Hemodialysis - A hemodialysis device and method are provided in which a hemodialyzer is designed for blood to flow past a semipermeable membrane and for a dialysate to flow in the opposite direction on the other side of the semipermeable membrane where uremic solutes are capable of diffusing from the blood into the dialysate passing the semipermeable membrane, and further designed in which a sorbent incorporated in a dialysate path as the dialysate passes the semipermeable membrane. The sorbent binds to non-urea uremic solutes and in particular to non-urea uremic solutes that bind to plasma proteins. In addition, the sorbent binds urea and inorganic ions much less effectively than non-urea uremic solutes and in particular to non-urea uremic solutes that bind to plasma proteins. | 2020-09-17 |
20200289735 | Method of Dialysis of Blood - The present disclosure provides a method for hemodialysis of blood, comprising providing a hemodialysis catheter having a low recirculation distal tip, a first and a second extension tubes that are configured to be connected to a dialysis machine, providing a hemodialysis machine with an arterial patient connector and a venous patient connector; conducting hemodialysis with the first extension tube connects to the arterial patient connector of the dialysis machine, and the second extension tube connects to the venous patient connector of the dialysis machine; and periodically reversing the first and second extension tubes connections to the arterial and venous patient connectors of the dialysis machine in a subsequent hemodialysis. The present disclosure also provides a hemodialysis catheter, comprising a switchable connection indicator indicating connection to arterial or venous flow path. The switchable connection indicator can be integrated with a clamp. | 2020-09-17 |
20200289736 | SYSTEM FOR THE EXTRACORPOREAL ELIMINATION OF CARBON MONOXIDE - A system for the extracorporeal elimination of carbon monoxide, includes at least one pump and a gas exchange chamber, wherein the at least one pump can be connected to the blood circulatory system of a person by way of a first tube section connectable to a cannula and is connected to a gas exchange chamber via a second tube section, wherein the system is configured to transfer blood, via the first tube section, from the blood circulatory system of the person by way of at least one pump into the gas exchange chamber, and to return the blood from the gas exchange chamber to the blood circulatory system of the person via the same first tube section. | 2020-09-17 |
20200289737 | CONTACTLESS ACTUATION FOR VALVE IMPLANT - An example magnetically activated implantable valve according to the present disclosure includes an implantable valve, the implantable valve including a first set of passive magnets, and an actuator configured to actuate the implantable valve. The actuator includes a second set of passive magnets corresponding to the first set of passive magnets. The first set of passive magnets is configured to interact with the second set of passive magnets to actuate the valve. Another example magnetically activated implantable valve and an implantable valve for controlling flow of an active fluid are also disclosed. | 2020-09-17 |
20200289738 | CENTRIFUGE AND METHOD OF USE - A centrifuge having a housing containing a rotational mechanism and a centrifugal container having a longitudinal axis. The rotational mechanism has a circuit including an electrical motor, a switch, and an internal electrical power source. The centrifugal container is operably connected to the rotational mechanism through the housing, and is rotatable about the longitudinal axis. The centrifuge is portable and is for single use. | 2020-09-17 |
20200289739 | COMBINATION FLUID INSTILLATION AND NEGATIVE PRESSURE DRESSING - Some illustrative embodiments of an instillation assembly for treating a tissue site may include a fluid distribution lumen and a fluid hub that may define a fluid instillation pathway. The fluid distribution lumen may be defined by a first film layer and a second film layer, and the fluid hub may be positioned in fluid communication with the fluid distribution lumen. The instillation assembly may be used in combination with a reduced-pressure assembly that may define a reduced-pressure pathway separate from the fluid instillation pathway. | 2020-09-17 |
20200289740 | DRUG DELIVERY STORAGE DEVICE AND SYSTEM - A drug delivery system includes a storage container defining one or more storage compartments and having at least one container sensor coupled thereto, a container condition change mechanism coupled to the storage container for imparting a change on one or more conditions of the one or more storage compartments, at least one drug delivery device adapted to deliver a drug to a user and adapted to be at least partially disposed within one or more of the one or more storage compartments, at least one delivery device sensor, a delivery device condition change mechanism coupled to the drug delivery device, and a controller coupled to the storage container. The storage container may be adapted to hold a number of drug delivery devices within a number of sealable storage compartments. The container sensor is adapted to sense a condition of the storage container, and the delivery device sensor is adapted to sense a condition of the at least one drug delivery device. The controller is adapted to instruct the container condition change mechanism and/or the delivery device change mechanism to impart a change on at least one condition of the storage container and/or the drug delivery device. | 2020-09-17 |
20200289741 | SYSTEM COMPRISING A PRE-FILLABLE SYRINGE AND A PACKAGE FOR THE PRE-FILLABLE SYRINGE - System comprising a pre-fillable syringe with a syringe barrel and a syringe tip and a package suitable and intended for receiving the pre-fillable syringe, wherein the syringe tip is provided with a tip cap, wherein the system comprises a replacement cap for the pre-fillable syringe, wherein the package is suitable and intended for receiving the replacement cap. | 2020-09-17 |
20200289742 | SYSTEM COMPRISING A PRE-FILLABLE SYRINGE AND A PACKAGE FOR THE PRE-FILLABLE SYRINGE - System comprising a pre-fillable syringe with a syringe barrel and a syringe tip and a package suitable and intended for receiving the pre-fillable syringe, wherein the syringe tip is provided with a tip cap, wherein the system comprises a replacement cap for the pre-fillable syringe, wherein the package is suitable and intended for receiving the replacement cap. | 2020-09-17 |
20200289743 | MEDICATION FLUID INFUSION SET COMPONENT WITH INTEGRATED PHYSIOLOGICAL ANALYTE SENSOR, AND CORRESPONDING FLUID INFUSION DEVICE - Disclosed is a medical device component for delivering medication fluid to a patient. The medical device component includes a fluid infusion device to regulate delivery of medication fluid, a body-mountable base unit, and a top cover assembly that is removably couplable to the base unit and to the fluid infusion device. The base unit includes a cannula to deliver medication fluid under the control of the fluid infusion device, and a physiological analyte sensor to measure a physiological characteristic. The base unit also includes an electronics assembly electrically connected to sensor leads to obtain measurements in the analog domain, to convert measurements into digital sensor data, and to communicate conditioned digital sensor data to the fluid infusion device. The top cover assembly is configured to provide both fluid and electrical connections for the base unit, by way of an infusion tube having sensor conductors integrated therein or otherwise associated therewith. | 2020-09-17 |
20200289744 | APPARATUS FOR SECURELY AND GENTLY HOLDING A FLEXIBLE ELONGATED MEDICAL DEVICE - A clip for holding a flexible elongated medical device. In embodiments, the clip has a hinge; first and second jaws movable with respect to each other about the hinge from a closed position to an open position, each of the jaws having a contact surface, the contact surface of the first jaw being disposed against the contact surface of the second jaw when the clip is in the closed position and away from the contact surface of the second jaw when the clip is in the open position; and flexible material disposed on at least one of the jaws, the flexible material comprising the contact surface. The invention also includes methods of holding a flexible elongated medical device. | 2020-09-17 |
20200289745 | DRUG DELIVERY DEVICE WITH DRIVE ASSEMBLY AND RELATED METHOD OF ASSEMBLY - Drug delivery devices and related methods of assembly are disclosed. The drug delivery device may include a main housing having an exterior surface releasably attachable to a patient, a container disposed in an enclosed space defined by an interior surface of the main housing, and a drive assembly. The container may include a reservoir containing a drug and a stopper. The drive assembly may include drive housing and a tether which slidably engages and is pulled taut against a guide surface of the drive housing. A first end of the tether may be wound around a capstan which is mounted rotatably relative to the drive housing. A second end of the tether may be operably connected to a stopper biasing member. The tether may initially retain the stopper biasing member in an energized state. When released, the stopper biasing member may expand to move the stopper through the reservoir. | 2020-09-17 |
20200289746 | FLUID DELIVERY APPARATUS HAVING A GAS EXTRACTION DEVICE AND METHOD OF USE - A gas extraction device for a fluid delivery apparatus includes a first layer and a vent membrane coupled to the first layer. The vent membrane enables a gas to pass through the vent membrane and prevents a fluid from passing through the vent membrane. The gas extraction device also includes a second layer coupled to the vent membrane opposite the first layer. The second layer has a first channel formed therethrough. In addition, the gas extraction device includes an impermeable membrane coupled to the second layer opposite the vent membrane. The first channel is configured to receive a fluid having a gas dispersed therein. The fluid is pressurized to move the fluid through the first channel against the vent membrane and to move the gas through the vent membrane. | 2020-09-17 |
20200289747 | DEVICE, SYSTEM AND METHODS FOR THE ORAL DELIVERY OF THERAPEUTIC COMPOUNDS - Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade within the wall to release the drug to produce a therapeutic effect. The preparation can be coupled to a delivery mechanism having one or more balloons or other expandable devices which are expandable responsive to a condition in the small intestine or other GI lumen to advance the preparation out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract. | 2020-09-17 |
20200289748 | Infusion Set And Inserter Assembly Systems and Methods - An inserter assembly comprising a first unit including a skin contacting face which surrounds an opening and a second unit housed within the first unit. The second unit comprises an infusion set base disposed within the opening and having a bottom face which is substantially level with the skin contacting face and covered at least partially with adhesive and further comprising a spring biased insertion assembly. The second unit further comprising a cannula sub assembly carried by an insertion sharp of the insertion assembly. The spring biased insertion assembly and a cannula of the cannula sub assembly are driven into skin and the cannula sub assembly is coupled into the infusion set base by an insertion spring which is released from an energy storing state after the skin has been tugged upward beyond a certain distance by the adhesive as the inserter assembly is withdrawn from the body. | 2020-09-17 |
20200289749 | DROPLET MEASUREMENTSYSTEM, DROPLET MEASUREMENT METHOD AND DROPLET MEASUREMENT PROGRAM - A droplet measurement system, etc. is provided that is capable of measuring the volume of a droplet with high precision by means of image processing with a lighter arithmetic load than before. The droplet measurement system is a droplet measurement system that measures the volume of a droplet dripping from a nozzle being provided with: an imaging unit that images an object to be imaged and outputs image data, wherein the imaging unit is placed such that a field of view is directed to a tip of the nozzle and a region extending vertically downward from the tip; an imaging control unit that sets the field of view of the imaging unit to a rectangular region long in a vertical direction and that causes the imaging unit to execute imaging; and an image processing unit that: acquires a plurality of images, in a temporal sequence order, that correspond to the rectangular region and that have captured therein the tip of the nozzle and the region extending vertically downward from the tip based on the image data output from the imaging unit; and that calculates the volume of the droplet based on the images acquired in a temporal sequence order. | 2020-09-17 |
20200289750 | INFUSION DEVICE AND METHOD FOR ADMINISTERING A MEDICAL FLUID TO A PATIENT - An infusion device ( | 2020-09-17 |
20200289751 | ELECTRONIC MODULES FOR A SYRINGE - An injection monitoring device includes a syringe having a barrel configured to contain a medicament and a plunger configured to be displaced linearly into the interior of the barrel to dispense the medicament, a flange positioned between a proximal end and a distal end of the injection monitoring device and configured to be gripped during performance of the injection, and one or more force sensors positioned to detect data associated with an amount of force applied to the injection monitoring device during performance of an injection. | 2020-09-17 |
20200289752 | Injection Device and Method of Making and Using the Same - Provided herein are an injection device and a method of injecting a patient. The injection device includes a base portion including a body section and a control section, at least one bracket secured to the body section, an articulation element secured to the control section, and a pusher plate coupled to the articulation element, wherein the articulation element moves the pusher plate with respect to the base portion. The method includes positioning at least two syringes in the injection device, placing an injection end of the injection device in contact with an injection site on the patient, and activating the articulation element, wherein activating the articulation element moves the pusher plate towards the at least two syringes, depressing a plunger and dispensing a fluid from the at least two syringes. | 2020-09-17 |
20200289753 | DRIVE UNIT FOR A MEDICAMENT DELIVERY DEVICE - A drive unit for a medicament delivery device is presented having an elongated plunger rod extending in a longitudinal direction, a drive force element capable of applying a drive force on the elongated plunger rod, and an actuator operably connected to the elongated plunger rod for releasably holding the elongated plunger rod in an energized state when the drive force element is exerting a drive force on the elongated plunger rod. An activator is operably connected to the actuator for releasably holding the actuator in a holding position where the actuator is designed to be movable from the holding position in a direction generally transversal to the longitudinal direction upon a displacement of the activator for releasing the plunger rod. | 2020-09-17 |
20200289754 | Injector Device - An injector device comprising an elongate housing having a proximal end and a distal end, and configured to receive a container of medicament, a needle sleeve mounted within the housing and moveable between an extended position in which the needle sleeve at least partially extends from the distal end of the housing, and a retracted position in which the needle sleeve is received further within the housing than in the extended position, a piston rod moveable longitudinally within the housing, a piston spring configured to bias the piston rod towards a distal end of the housing to engage a container of medicament when received within the housing, and a release mechanism configured to control actuation of the piston rod. The release mechanism comprises a locking arm moveable between a locked position in which the locking arm is in cooperating engagement with the piston rod and prevents movement of the piston rod, and a release position in which the locking arm is out of engagement with the piston rod so that the piston rod is free to move longitudinally within the housing. The needle sleeve is configured such that movement of the needle sleeve from the extended position to the retracted position causes the locking arm to move from the locked position to the release position. | 2020-09-17 |
20200289755 | Injector Device - An injector device includes an elongate housing configured to receive container of medicament. The injector device also includes a needle sleeve mounted within the housing and moveable between an extended position in which the needle sleeve at least partially extends from the distal end of the housing, and a retracted position in which the needle sleeve is received further within the housing than in the extended position. The injector device also includes a release mechanism configured to control actuation of a piston rod. The release mechanism includes a rotatable member disposed within the housing and in cooperating engagement with the needle sleeve such that movement of the needle sleeve from the extended position to the retracted position causes the rotatable member to rotate within the housing from a first position to a second position. | 2020-09-17 |
20200289756 | AUTO INJECTOR DEVICE - Aspects of an auto injector device are provided which allow for increased reusability, portability and convenience, thermal insulation, and safety. The auto injector device is encapsulated in a case for a mobile communications device and includes a cartridge, an outer casing fixed to the case and attached to the cartridge and including a piston, and a sensor attached to the case. The cartridge is configured to contain a fluid and includes a needle. The piston is configured to pump the fluid in the cartridge through the needle in response to application of a force during injection of the auto injector device. The cartridge is detachable from the outer casing. The sensor is in wireless communication with an emergency alert system, and the sensor is configured to sense movement of the needle and to communicate with the emergency alert system in response to application of the force during the injection. | 2020-09-17 |
20200289757 | Injection Device Having Variable Dosing - An injection device for injecting medicament in a patient comprises a housing configured to house a fluid reservoir that has one of a plurality of volumes of medicament. An injection conduit fluidly coupled to the fluid reservoir defines a fluid pathway from the fluid reservoir to the patient. A firing mechanism is coupled to the fluid reservoir and is configured to expel the medicament from the fluid reservoir through the injection conduit. A volume setting mechanism is coupled to the firing mechanism and is configured to select the one of the plurality of volumes of medicament for the firing mechanism to expel. A dose setting mechanism is configured to select all or a fraction of the one of the plurality of volumes of medicament that is injected from the injection conduit when the firing mechanism is actuated. | 2020-09-17 |
20200289758 | PHARMACEUTICAL CONTAINER AND LIQUID COMPOSITION - A pharmaceutical container for drug delivery includes a barrel configured to slidably receive a stopper. The stopper has a proximal end suitable for contacting a plunger rod and a distal end suitable for contacting a pharmaceutical composition. The stopper has a circumferential surface partially contacting an inner surface of the barrel. A surface roughness of the inner surface of the barrel declines from the stopper's start position to its end position by at least 3% of at least one of Ra roughness or Rms roughness. | 2020-09-17 |
20200289759 | PHARMACEUTICAL CONTAINER AND LIQUID COMPOSITION - A pharmaceutical container for drug delivery includes a barrel configured to slidably receive a stopper. The container exhibits a ratio of a break loose force (BLF) relative to a glide force (GF) of BLF/GF≤2 during a break loose and glide force test and a total glide force variation TGFV=GF | 2020-09-17 |
20200289760 | SUBASSEMBLY FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE - The present specification relates to a subassembly for a drug delivery device, the subassembly comprising:
| 2020-09-17 |
20200289761 | SYRINGE HAVING AT LEAST ONE RADIALLY-OUTWARDLY EXTENDING PANEL - A syringe is provided herein for injecting medication into a patient, the syringe including a tubular barrel having opposing inner and outer surfaces, an open proximal end, and a distal end having a wall extending thereacross. An opening is defined in the wall with a needle mount extending distally from the wall about the opening. A first panel extends radially outwardly from the outer surface of the barrel, the first panel having opposing first and second faces. Further, a first scale including a series of spaced-apart first graduations is disposed on the first face of the first panel. Advantageously, with the subject invention, a syringe may be provided having a planar portion, in addition to its barrel, with graduations marked thereon for improved viewing by a practitioner in determining a proper dose amount. | 2020-09-17 |
20200289762 | INJECTION DEVICE WITH FLEXIBLE DOSE SELECTION - An injection device incorporating a dose setting mechanism is presented where the dose setting mechanism contains a dose selector having one or more dose stops corresponding to a finite set of predetermined fixed doses, where the set of finite predetermined fixed doses includes a lowest fixed dose and one or more higher fixed doses, and where at least one of the one or more higher fixed doses is equal to the lowest fixed dose plus a fractional amount of the lowest fixed dose. The dose setting mechanism can further include a floating spline that is rotationally engaged with a snap element such that the snap element can rotate relative to the floating spline during both dose setting and dose delivery. | 2020-09-17 |
20200289763 | INJECTION DEVICE WITH FLEXIBLE DOSE SELECTION - An injection device incorporating a dose setting mechanism is presented where the dose setting mechanism contains a dose selector having one or more dose stops corresponding to a finite set of predetermined fixed doses, where the set of finite predetermined fixed doses includes a lowest fixed dose and one or more higher fixed doses, and where at least one of the one or more higher fixed doses is equal to the lowest fixed dose plus a fractional amount of the lowest fixed dose. The dose setting mechanism can further include a floating spline that is rotationally engaged with a snap element such that the snap element can rotate relative to the floating spline during both dose setting and dose delivery. | 2020-09-17 |
20200289764 | Drug Delivery Device - The present specification relates to a drug delivery device comprising:
| 2020-09-17 |
20200289765 | PLUNGER COVERS AND PLUNGERS FOR USE IN SYRINGES - A plunger cover for use with a syringe includes a sealing portion adapted to form a seal with the syringe and a central portion adapted to contact fluid within the syringe. The central portion can, for example, be more rigid than the sealing portion. The sealing portion and the central portion are connected in an overmolding process. The sealing portion can, for example, be formed from a thermoplastic elastomer or a thermoplastic polyurethane. The central portion can, for example, be formed from polypropylene, acrylonitrile butadiene styrene, polycarbonate or copolymers thereof. | 2020-09-17 |
20200289766 | METHOD AND APPARATUS FOR APPLYING AN ANESTHETIC AND BACTERICIDE - A method and an apparatus for applying an anesthetic that includes a receptacle having an upper end, a substantially hollow interior, a lower end having a tube or nozzle extending therefrom, and an attachment for attaching to the barrel of a syringe or vice versa. The receptacle receives a container or canister containing an endothermic gas or vapor (propellant) that rapidly absorbs heat when released to the atmosphere. A depressible actuating member or trigger propels the gas or vapor through an outlet nozzle that is oriented to project a stream of gas or vapor along a delivery axis that intersects a delivery axis of the needle, therefore, the gas or vapor can be successively delivered to an injection site with minimal repositioning of the housing. | 2020-09-17 |
20200289767 | GAS RECIRCULATION SYSTEM AND METHOD - Gas recirculation systems for use in endoscopic surgical procedures including a gas recirculation pump are disclosed. The gas recirculation pump may work in conjunction with an insufflator used to inflate a patient's peritoneal cavity during surgery. The gas recirculation system may recirculate a high flow rate of gas from and to the patient while filtering particulate matter out of the gas and while maintaining an adequate moisture content in the gas. The gas recirculation pump may include a disposable pump cartridge releasably connected to a pump motor. A controller may detect a fault or safety condition in the gas recirculation system based on the load placed on the pump motor. | 2020-09-17 |
20200289768 | DRUG DELIVERY DEVICES AND METHODS FOR ADMINISTERING SUBSTANCES TO A BODY CAVITY BY HETEROGENOUS AEROSOLIZATION - The present invention provides means and methods for delivering a predetermined volume of a substance, within at least one body cavity of a subject, comprising a predefined volume for containing the predetermined volume of the at least one substance; a delivery end for placement in proximity to the body cavity; the delivery end comprises at least one orifice of diameter D [mm]; a valve mechanically connectable to the container, characterized by at least two configurations: (i) an ACTIVE CONFIGURATION in which the valve enables delivery of predetermined volume V | 2020-09-17 |
20200289769 | DEVICE FOR DISPENSING A FLUID PRODUCT - A fluid dispenser device having a dispenser head; an air expeller; and a reservoir containing a single dose of fluid. The reservoir includes a proximal axial end and a distal axial end, and is removably mounted so that after the device has been actuated, the empty reservoir can be removed from the device and replaced by a new full reservoir. The air expeller is adapted to return to its rest position to enable a new actuation with the new full reservoir. The dispenser head includes a proximal perforator tip to perforate the proximal axial end of the reservoir. The device includes a movable perforator member that slides axially around the dispenser head between a loading position and an actuation position and includes a distal perforator tip adapted to perforate the distal axial end of the reservoir when the movable perforator member is moved into its actuation position. | 2020-09-17 |
20200289770 | NASAL DRUG DELIVERY APPARATUS AND METHODS OF USE - A nasal droplet delivery device and related methods for delivering precise and repeatable dosages to a subject via the nasal passageways and sinus cavities is disclosed. The droplet delivery device includes a housing, a nosepiece, a reservoir, an ejector mechanism, and at least one differential pressure sensor. The droplet delivery device is automatically actuated by the user when the differential pressure sensor senses a predetermined pressure change within the nosepiece. The droplet delivery device is then actuated to generate a plume of droplets having an average ejected particle diameter of greater than about 6 microns, preferably greater than about 10 micron, so as to target the nasal passageways and sinus cavities of the user. | 2020-09-17 |
20200289771 | MEDICAL DEVICE LOCATION TRACKING - Location tracking of medical devices or any consumer device. A location monitoring system can include a wireless communication system, such as a Global System for Mobile (GSM), a cellular system, a Wi-Fi system, or a global positioning system, programmed to transmit the device location under certain events. The system can also be configured to maintain the back up battery life by periodically turning a second global system for mobile communication on and off for a predetermined period of time. The system can also be configured to activate when the device is taken outside a predefined boundary, for example, a hospital. | 2020-09-17 |
20200289772 | ADAPTIVE PATIENT CIRCUIT COMPENSATION WITH PRESSURE SENSOR AT MASK APPARATUS - In certain embodiments, a system for providing respiratory therapy is provided. The system comprises a pressure generator for generating a pressurized flow of breathable gas; a subject interface for guiding the pressurized flow of breathable gas to a point of delivery at or near the airway of the subject, wherein the subject interface causes a pressure drop between an output of the pressure generator and the point of delivery; one or more sensors for generating output signals conveying information related to gas parameters of the pressurized flow of breathable gas; one or more processors configured to adjust one or more model parameters of a parameter-based model that models the subject interface; estimate the pressure drop between the output of the pressure generator and the point of delivery based on the adjusted model parameters; and adjust levels of the gas parameters based on the estimated pressure drop. | 2020-09-17 |
20200289773 | Mechanical User Control Elements For Fluid Input Module - A multi-lumen catheter for cleaning an inner surface of a tracheal ventilation tube is provided, which enables single-handed simultaneous activation of inflation of an inflatable element and suctioning in a closed suction system for use with the in tracheal ventilation tube. The closed suction system allows catheters to be used repeatedly without being detached from the tube system including the ventilation air supply. The cleaning catheter is insertable into the tracheal ventilation tube, and is shaped so as to define one or more distal suction orifices. The cleaning catheter comprises an elongate, flexible, tubular catheter main body, and an inflatable element, which is mounted to the catheter main body. An input module is coupled to the cleaning catheter, and comprises an inflation module, which comprises an inflation chamber separate from a suction source. The input module also comprises a flow regulator, which is shaped so as to define a suction port coupleable in fluid communication with the suction source. | 2020-09-17 |
20200289774 | RESPIRATORY MASK WITH NASOGASTRIC TUBE PATH - A respiratory mask can be used to provide therapy to patients who also require a nasogastric (NG) tube. The mask seal can include a path that is designed to deform around an NG tube or other without lifting the mask away from a patient's face. The deforming path can help to minimize gaps that form between the patient's face and the mask seal as a result of the tube, thus reducing leaks and improving the efficacy of the treatment. | 2020-09-17 |
20200289775 | BREATHING ASSISTANCE APPARATUS - A patient interface that is comfortable for a user to wear is disclosed. The patient interface includes a forehead rest and cushion. In particular the cushion includes a deformable resilient member that when compressed creates a uniformly and gradually increasing force while evenly distributing the pressure on the forehead of the patient. | 2020-09-17 |
20200289776 | HEADGEAR FOR A RESPIRATORY MASK AND A METHOD FOR DONNING A RESPIRATORY MASK - Headgear for a respiratory mask includes a strap arrangement including front strap portions adapted to be disposed over a patient's cheeks and having front ends adapted for attachment to an airway interfacing portion, top strap portions connected to respective front strap portions and adapted to be disposed over the top of a patient's head and to connect to each other, and a back strap extending rearwardly from and connecting respective junctions of the front strap portions and top strap portions or regions adjacent these junctions and adapted to locate underneath a patient's occiput. In use with a patient having long hair, the back strap is adapted to extend under the patient's hair and urge upwardly on the patient's hair and against the patient's head beneath the occiput. In use with a patient having short hair, the back strap is adapted to urge against the patient's head beneath the occiput. In an embodiment, front strap portions of the headgear may be provided with a sleeve or cover (e.g., constructed of a fleece material) to enhance comfort in use. | 2020-09-17 |
20200289777 | HEADGEAR FOR BREATHING MASK - An interface assembly includes an interface, such as a mask, that is secured to a head using a headgear assembly. The headgear assembly can include at least one halo portion and a plurality of straps. The headgear assembly can include both a front halo portion and a rear halo portion. In some arrangements, the headgear and mask define an adjustable closed loop. In some arrangements, the headgear can include one or more rigid portions that contact the user's face to at least partially isolate a seal of the mask from tightening forces applied to the headgear. In some arrangements, the mask is an oral-nasal mask and the headgear applies a force to the mask comprising an upward force component. In some arrangements, the headgear can be contoured to the user's head. | 2020-09-17 |
20200289778 | RESPIRATORY GAS HUMIDIFIER - A gas humidifier can have a gas channel comprising an inlet and an outlet. A portion of the gas channel can have a region having a reduction in cross-sectional area relative to the portions of the gas channel outside of the region. A water conduit can extend from the region to a water reservoir. A heating element can heat water entering the region from the water conduit. Water vaporized using the heating element can join the flow of gases passing through the gas channel in use. | 2020-09-17 |
20200289779 | NEBULIZER ORIENTATION APPARATUS - There is provided a nebulizer orientation apparatus for orientating an aerosol or mist forming means of the nebulizer into a substantially vertical position relative to the ground level under force of gravity. Particularly, there is provided a nebulizer orientation apparatus comprising first and second straight hollow bodies in flow communication with each other via a joint means, which joint means facilitating movement of the first and second straight hollow bodies relative to each other in a first plane facilitated by the joint means, and wherein the first straight hollow body is weighted relative to the second straight hollow body to facilitate displacement of the first body under force of gravity relative to the second body. | 2020-09-17 |
20200289780 | CONNECTORS FOR RESPIRATORY ASSISTANCE SYSTEMS - Connectors for respiratory assistance systems are disclosed that are configured to at least decrease the proportion of condensate that drains into an inspiratory conduit. The connectors include a setup that causes the portion of a wye-piece connected to an expiratory conduit to be positioned below the portion of the wye-piece connected to the inspiratory conduit. The connector can alternatively, or additionally, include a wye-piece that includes a ball attached to the wye-piece adjacent the inspiratory conduit port such that when the ball is connected to a medical stand, the expiratory conduit port is positioned below the inspiratory conduit port. The connector can alternatively or additionally include a circuit hanger that includes a cradles for both conduits and a ball attached to the circuit hanger adjacent the inspiratory conduit cradle such that when the ball is connected to a medical stand, the expiratory conduit cradle is positioned below the inspiratory conduit cradle. The connector can alternatively or additionally include a coaxial wye-piece that includes an inspiratory branch, an expiratory branch, and a patient end. The tip of the inspiratory branch that is internal to the coaxial wye-piece may have a lip and a narrowed diameter, features which obstruct or reduce condensate from entering the inspiratory branch and the inspiratory conduit regardless of the coaxial wye-piece orientation or position. | 2020-09-17 |
20200289781 | EXHALATION PORT - Several embodiments of exhalation ports for use respiratory systems are described. Some of the embodiments provide an elongate body defining a lumen through which gases may flow. A plurality of tapered openings is arranged on a portion of the elongate body and configured to vent gases. A shroud extends from the elongate body and surrounds one or more of the plurality of tapered openings. The exhalation port is arranged to removably connect in-line with a circuit for delivering gases to a patient. | 2020-09-17 |
20200289782 | COMPONENTS FOR MEDICAL CIRCUITS - Condensation or “rain-out” is a problem in medical circuits and previous attempts to manage and/or prevent rain-out have resulted in relatively expensive and/or difficult to manufacture medical circuit components. The subject patent provides an improved medical circuit component for managing rain-out. In particular the component may be an improved breathing tube, or insufflation system limb comprising a helically corrugated tube preferably incorporating a heater wire. | 2020-09-17 |
20200289783 | USABILITY FEATURES FOR RESPIRATORY HUMIDIFICATION SYSTEM - A humidification system for delivering humidified gases to a user can include a heater base, humidification chamber having an inlet, outlet, and associated fluid conduit, and breathing circuit including a supply conduit, inspiratory conduit, and optional expiratory conduit. The humidification system can include various features to help make set-up less difficult and time-consuming. For example, the supply conduit, inspiratory conduit, and optional expiratory conduit can be coupled into a one-piece circuit to aid set-up. Various components can be color-coded and can have corresponding structures to indicate which components should be connected to one another during set-up. Such features can also help make the set-up process more intuitive for an operator, which can reduce the need for specialized training and reduce the number of potential errors. | 2020-09-17 |
20200289784 | OXYGEN MONITORING AND CONTROL SYSTEM - An Automatic Supplemental Oxygen Control unit, a portable device that automatically monitors and adjusts the flow of supplemental oxygen to the subject in response to the oximetry and other readings derived from sensors attached to the subject and the oxygen source and provides programmed responses to physical inputs from such sensors to provide a closed loop oxygen delivery system. | 2020-09-17 |
20200289785 | TREATMENT OF CENTRAL NERVOUS SYSTEM CONDITIONS USING SENSORY STIMULUS - The invention discloses methods and systems for modulation of the central nervous system and more particularly for modulation of brain oscillatory activity and the brain networks that give rise to it. The methods involve using one or more non-invasive stimuli, either alone or in combination, to increase, decrease, or otherwise modulate neural oscillations, the rhythmic and/or repetitive electrical activity generated spontaneously and in response to stimuli by neural tissue in the central nervous system. Various embodiments concern methods and devices for detecting sub-optimal or pathological neural oscillatory patterns, developing treatment protocols to modify the neural oscillations in a desired manner, introducing a non-invasive stimulus or stimuli through one or more sensory pathways to treat the conditions, and for adjusting the treatment protocol to optimize the therapeutic effect of the stimulus or stimuli. | 2020-09-17 |
20200289786 | MEASUREMENT APPARATUS AND MEASUREMENT SYSTEM - A measurement apparatus includes a wearing portion, a body portion, a first measurement portion, and a second measurement portion. The wearing portion is configured to be worn at an auricle of a subject. The body portion is joined to the wearing portion. The first measurement portion is joined to the body portion, and configured to be worn by the subject and measure oxygen saturation. The second measurement portion is joined to the body portion, and configured to be in contact with the subject in a state in which the wearing portion is worn and measure body temperature. | 2020-09-17 |
20200289787 | SUPPORT SYSTEM, SUPPORT METHOD, AND SUPPORT PROGRAM - A support system, a support method, and a support program in the form of a non-transitory computer readable medium, which supports selection of a medical instrument and selection of a use form of the medical instrument. A support system includes the data acquisition unit that acquires health care worker data on a health care worker, medical institution data on a medical institution, patient data on a patient, and operation data on a past operation experience of the health care worker, a learning unit that performs machine learning using the health care worker data, the medical institution data, the patient data, and the operation data, and a presentation unit that presents a medical instrument recommended for use in operation on the patient and a recommended use form of the medical instrument based on a result of the machine learning. | 2020-09-17 |
20200289788 | Apparatus and methods for Loading Suture - Various embodiments of a cartridge for loading a suture onto a suturing instrument are disclosed. In some embodiments, the cartridge is operable for loading a pre-tied knot formed from the suture onto the suturing instrument. The suturing instrument is typically of the type having a suture passing member defining a suture receiving passage therein. In some embodiments, the cartridge comprises a housing defining a chamber, and a partially pre-tied knot mounted about the housing or the chamber. The cartridge additionally provides a base coupled to the housing, the base defining a seat for releasably holding a portion of a suture to be aligned with, and. transferred to, the suturing instrument. The portion of the suture may be held independently, or it may be coupled to a component such as a ferrule or shuttle. | 2020-09-17 |
20200289789 | STEERABLE MEDICAL DEVICE AND METHOD - In various examples, a system includes a steerable medical device including a handle including a longitudinal axis. An elongate shaft extends distally from the handle. The elongate shaft includes a distal tip and a lumen through the elongate shaft. At least four pullwires are disposed within the handle and extending to and anchored proximate the distal tip of the elongate shaft. At least two actuators are associated with the handle. The at least two actuators are operably coupled to the at least four pullwires with actuation of the first actuator causing tension in the first or second pullwire to deflect the distal tip in a first or second tip direction, respectively, and actuation of the second actuator causing tension in the third or fourth pullwire to deflect the distal tip in a third or fourth tip direction, respectively. | 2020-09-17 |
20200289790 | INVASIVE MEDICAL DEVICE AND MANUFACTURING METHODS - An invasive medical device ( | 2020-09-17 |
20200289791 | INTEGRATED VASCULAR DELIVERY SYSTEM - An integrated vascular delivery system and method of use, the system including: a frame having a catheter hub that provides a first anchoring point on the patient and receives a catheter insertable in the patient to transfer fluid at an insertion site, a stabilization hub that provides a second anchoring point on the patient, at least one lateral member extending between the catheter and stabilization hubs, and a fluidic channel. The frame operates in a folded configuration in which the hubs are coupleable and an unfolded configuration in which the anchoring points are distributed around the insertion site to anchor the frame to the patient, thereby stabilizing the catheter. In some embodiments, the system further includes a septum that helps prevent fluid leakage from the catheter hub, or a needle shield that covers the distal end of a needle used during catheter insertion. | 2020-09-17 |
20200289792 | MEDICAL DEVICE WITH RESILIENTLY RETRACTING SAFETY NEEDLE - A medical device for percutaneous or venous access for the purposes of administering a fluid to a patient or sampling from one is disclosed. The device includes a cannula holder that has a part or portion of cross-section which is reduced or different from its distal end and proximal end. The part or portion of reduced or different cross-section allows cannula holder to deform within the body of the device when activating means are activated to separate the cannula holder from an immobilising member allowing the cannula holder to move in the body of the device and re-enter and disappear within such body of the cannula. | 2020-09-17 |
20200289793 | Multi-Purpose Catheter for Brachytherapy and Intratumoral Injection - A single treatment catheter is provided for delivery of brachytherapy radiation in combination with intratumoral injection into tumor tissue with a single skin and tumor insertion site. The catheter also enables precise delivery of anti-cancer agents, such as immunotherapy or other medical substances, to specific locations within the tumor with radiographic confirmation of the injection delivery area and location. | 2020-09-17 |
20200289794 | DUAL HUB INTRODUCER SHEATH - There is provided an introducer system for percutaneously delivering a first and a second medical device to a patient. The system may comprise an introducer sheath having a longitudinal axis and a lumen formed therein. The system may also comprise a hub coupled to a proximal end of the sheath. The hub may comprise a first arm having a first lumen and a first hemostasis valve for the passage of the first medical device. The hub may also comprise a second arm coupled to the first arm and having a second lumen and a second hemostasis valve for the passage of the second medical device. Further, the hub may comprise a connection port such that the first lumen and the second lumen are in communication with the lumen of the introducer sheath for the passage of at least one of the first and second medical devices through the introducer sheath for delivery to the patient. | 2020-09-17 |
20200289795 | GUIDEWIRE - A guidewire comprises a core shaft, a coil body covering a distal end portion of the core shaft, and a coating agent covering an outer periphery of the coil body, wherein the coil body includes a distal coil body disposed on a distal side of the coil body, and a proximal coil body disposed on a proximal side of the distal coil body, a surface roughness of the proximal coil body is higher than a surface roughness of the distal coil body. | 2020-09-17 |
20200289796 | Transseptal Puncture Apparatus and Method for Using the Same - Devices and methods for performing a transseptal puncture procedure using a device which includes either an untapered or tapered blunt end cannula disposed in an introducer carrying a sharp guidewire disposed longitudinally through the lumen of the blunt cannula, and a blunt end dilator wherein the guidewire is flexible and has an atraumatic shape at its tip. The cannula gives the more flexible introducer a defined shape and steerabilty allowing an ordinarily skilled physician to easily access a selected location on the septal wall of the heart for transseptal puncture and introducer placement thereacross without employing an exposed sharp end needle during the procedure. | 2020-09-17 |
20200289797 | STABILIZING AND SEALING CATHETER FOR USE WITH A GUIDING CATHETER - A coaxial stabilizing and sealing catheter provides increased support to a guide catheter that is seated in an ostium of a branch artery by extending through and out of a distal end of the guide catheter and anchoring in position within the vessel that is being treated. The stabilizing and sealing catheter includes, as part of a relatively flexible distal section, a balloon that locks the distal end of the stabilizing and sealing catheter in place to provide support to the therapeutic devices that are introduced and further seals the artery to prevent blood from entering the artery. A sealing cuff at a proximal end of the stabilizing and sealing catheter provides a seal between the exterior of the stabilizing and sealing catheter and the interior of the guide catheter. In addition, a fixing mechanism it utilized to lock the guide catheter in place to exchange therapeutic devices. | 2020-09-17 |
20200289798 | ENDOVASCULAR MOBILE BALLOON SUPPORT CATHETER - The invention refers to endovascular catheters and methods useful to endovascular surgery. In particular, it refers to support catheters with balloons that are used for the placement or the forwarding of the guidewire through demanding tortuosity and important vascular stenoses in cases where the guidewire needs the best possible backup support of the catheter. This is achieved with the development of an endovascular support catheter with a mobile balloon, which has the ability to move along the body of the catheter, at its distal part. The movement of the balloon is achieved with the use of two mobile external rings, one inner wire circuit, and one control handle which is found at the proximal end of the device. The mobile balloon allows the catheter to move inside the vessel even when it is inflated and basically anchored within the vessel. | 2020-09-17 |
20200289799 | METHODS AND DEVICES FOR TRANSCERVICAL TREATMENT OF ENDOMETRIAL CANCER AND HYPERPLASIA - An infusion catheter includes a housing, a proximal shaft assembly, a first distal shaft assembly and a second distal shaft assembly. The housing has one or more inflation ports and one or more infusion ports. The proximal shaft assembly supports a first balloon. The first distal shaft assembly extends distally from the proximal shaft assembly and supports a first distal balloon. The second distal shaft assembly extends distally from the proximal shaft assembly and supports a second distal balloon. The first and second distal shaft assemblies define infusion openings in fluid communication with the one or more infusion ports. The infusion catheter may be inserted into a uterine cavity to occlude tubal ostia and an internal cervical OS of the uterine cavity for sealing the uterine cavity. A therapeutic agent may be delivered through the infusion catheter and into the sealed uterine cavity to treat the uterine cavity. | 2020-09-17 |
20200289800 | MULTIPLE BALLOON VENOUS OCCLUSION CATHETER - A multiple balloon catheter designed to quickly and easily obtain hemostasis during open and minimal access surgery in the event of venous injury. | 2020-09-17 |
20200289801 | BLOW MOLDED COMPOSITE DEVICES AND METHOD - The present disclosure is directed toward a composite balloon comprising a layer of material having a porous microstructure (e.g., ePTFE or expanded polyethylene) and a thermoplastic polymeric layer useful for medical applications. The layers of the composite balloons become adhered through a stretch blow-molding process. Methods of making and using such composite balloons are also described amongst others. | 2020-09-17 |
20200289802 | Drainage Catheter System Including a Hub - A drainage device may include a catheter including a proximal end and a distal end. The drainage device may further include a hub coupled to the proximal end of the catheter. The hub may include a fastener element configured to secure the distal end of the catheter. In some aspects, the fastener element may be a hinged element. In some aspects, the drainage device may further include a puncture element including a tip and an expander portion. In still other aspects, the puncture element may also include an attachment portion. | 2020-09-17 |
20200289803 | Cerebrospinal Fluid Shunt Valve System - The present invention provides a cerebrospinal fluid shunt system that monitors the intracranial pressures over a portion of a monitoring cycle to calculate short intervals of drainage for every monitoring cycle necessary to produce the desired pressure correction. The system operates to significantly reduce the time during which draining occurs allowing tissue surrounding the catheter to rebound from the catheter holes returning to its normal position for a sufficient amount of time to recover its normal shape. | 2020-09-17 |
20200289804 | FLORA TREATMENT - A flora treatment of the invention includes a step (A) in which an instrument is introduced into a lumen; a step (B) in which the instrument is made to reach an intestinal cecum; a step (C) in which an appendico is recognized; and a step (D) in which probiotics is supplied to the appendico. | 2020-09-17 |
20200289805 | Method and System for Treating Vulvodynia - Among other things, a system and a method are provided for generating space-filling foam for treating vulvodynia with medication compounded of multiple reactants; the system comprises an aerosol surmounted on a vulva-enclosing container configured to seal the vulva; the actuator on the aerosol operates a one-way valve to dispense said space-filling foam; and the method includes the following steps: selecting the vulvar cap delivery dispenser, affixing the dispenser over the vulva, depressing the pressure-sensitive switch operating the valve to deliver the appropriate quantity of medication in a space-filling foam, removing the delivery dispenser, and cleansing the dispenser; repeating the procedure according to a treatment regimen. | 2020-09-17 |
20200289806 | OXYGEN THERAPY WITH FLUID REMOVAL - An apparatus for treating a tissue site includes a dressing, an oxygen source, a valve, and a negative-pressure source. The dressing is configured to be sealed around the tissue site. The oxygen source is fluidly coupled to the dressing and configured to provide a low flow of oxygen. A first port of the valve is fluidly coupled to the dressing and the valve moves between a closed position preventing flow through the valve and an open position permitting flow through the valve. The negative-pressure source is fluidly coupled to a second port of the valve and provides negative pressure to the second port of the valve at a non-therapeutic level. The valve separates the negative-pressure source from the dressing and selectively opens when a positive pressure is applied on an upstream side of the valve. | 2020-09-17 |
20200289807 | METHODS AND DEVICES FOR LOCALIZING COMPOSITIONS - Methods for limiting dissipation of neurotoxins and dermal fillers from an injection site are disclosed, which includes applying a repellant electric field to the skin around the injection site to limit dissipation of an injected neurotoxin or dermal filler. | 2020-09-17 |
20200289808 | APPLICATOR FOR APPLYING A MICRONEEDLE ARRAY TO SKIN - An applicator and method for applying a microneedle array to skin. The applicator can include a body having a first portion and a second portion defining a cavity, the second portion having a slot presented on an outside surface for insertion of the microneedle array into the cavity. The first portion and the second portion are slidable relative to one other along an axis enabling the body to be in an unprimed configuration and a primed configuration. The applicator further includes a door operable with the second portion, the door being movable from a first door position to a second door position, wherein when the device is in the unprimed configuration, the door at least partially obstructs the slot and access into the cavity. When the device is in the primed configuration, the door does not obstruct the slots and enables access into the cavity. | 2020-09-17 |
20200289809 | FUNCTIONAL MEMBER AND METHOD OF FABRICATING THE SAME - A functional member includes: a plurality of microneedles on a surface. Further, the microneedles adjacent to each other are spaced apart by a pitch ranging from 1 to 500 μm, and the microneedles have a diameter ranging from 0.25 to 250 μm and have a height ranging from 5 to 200 μm. | 2020-09-17 |
20200289810 | DUAL LUMEN TUBING EXTENDING FROM BODILY INSERTED MEDICAL APPLIANCE AND COLOCATED INFUSION AND VACUUM PUMPS - An integrated multi-lumen tubing includes two or more lumens. A webbing is provided between each of said two or more lumens and holding the two or more lumens together as a ribbon. A set of terminations are provided at opposing ends of each of the two or more lumens. A sheath can also be provided surrounding the two or more lumens. A system for supply of intravenous fluid and vacuum to a patient includes the aforementioned integrated multi-lumen tubing. An intravenous bag or bottle is provided that is in fluid communication with an infusion pump. The integrated multi-lumen tubing connects the infusion pump and a vacuum pump to a percutaneous access device (PAD). A method of using said integrated multi-lumen tubing to delivery simultaneously two or more inputs into a subject in need thereof is also provided. | 2020-09-17 |
20200289811 | APPARATUSES FOR CLEANING CATHETER PORTS - Methods and apparatus for cleaning a central venous catheter port are disclosed. An apparatus includes a body, a coupling configured to connect the body to the hub, a cleaning cap coupled to the body, and an actuator disposed within the body for rotating and translating the cap relative to the hub. The cleaning cap includes a cap body defining a cavity and a cleaning member disposed within the cavity, the cleaning member having threads that engage with the threads on the hub. | 2020-09-17 |
20200289812 | Connector System - A connector which couples to an outlet conduit to decrease an outlet conduit passageway pressure differential between outlet conduit opposing first and second ends, whereby the connector includes a mixing chamber having a first inlet port in fluidic communication with a connector first open end and the mixing chamber; an outlet port in fluidic communication with the mixing chamber and a connector second open end; and a second inlet port in fluidic communication with the connector second open end and the mixing chamber. Additionally, a connector including a connector internal surface defining a connector passageway which communicates between connector first and second open ends; and a sensor module operatively coupled to the connector passageway to sense a parameter of a first fluid flowing in a first fluid flow path through the connector passageway. | 2020-09-17 |
20200289813 | ELECTRICAL TREATMENT DEVICE - A electrical treatment device ( | 2020-09-17 |
20200289814 | SYSTEMS AND METHODS FOR PERIPHERAL NERVE STIMULATION IN THE FINGER OR HAND TO TREAT HAND TREMORS - Systems, devices, and methods for stimulating peripheral nerves in the fingers or hand to treat tremor are described. For example, a wearable ring device for delivering electrical stimulation to sensory nerves in a patient's finger can include an annular ring having a plurality of electrodes and a detachable unit having a power source and a pulse generator. | 2020-09-17 |
20200289815 | Method and System For Physiological Target Localization From Macroelectrode Recordings and Monitoring Spinal Cord Function - Provided herein are a method and system are provided for the localization of clinically relevant electrophysiological signals necessary for the proper placement of the electrodes for nervous system stimulation. The system provides electrical and mechanical means to stimulate or excite neural structures in order to elicit specific neural responses. The method can include mechanical vibratory stimulation, cutaneous electrical stimulation, electrical stimulation of the peripheral nerves, or photic stimulation, and recording of local field potentials and extracting evoked potentials in response to stimulation. The method also includes extracting components of the evoked potentials that relate the signal in the evoked potentials to specific anatomical structures and localization of the source of the evoked potentials recorded so as to identify the location of the source relative to the recording electrode with high resolution by sampling the evoked potentials with a relative large (macro) electrode that is moved in small incremental steps. | 2020-09-17 |
20200289816 | SUBSTERNAL LEADLESS ELECTRICAL STIMULATION SYSTEM - Implantable leadless cardiac pacing systems and methods for providing substernal pacing using the leadless cardiac pacing systems are described. In one embodiment, an implantable leadless cardiac pacing system includes a housing, a first electrode on the housing, a second electrode on the housing, and a pulse generator within the housing and electrically coupled to the first electrode and the second electrode. The housing is implanted substantially within an anterior mediastinum of a patient and the pulse generator is configured to deliver pacing pulses to a heart of the patient via a therapy vector formed between the first and second electrodes. | 2020-09-17 |
20200289817 | ELECTRICALLY ANESTHETIZING A PERIPHERAL NERVE WITH ON-DEMAND ELECTRICAL NERVE BLOCK FOR CHRONIC PAIN MANAGEMENT - Chronic pain management can be achieved by electrically anesthetizing a peripheral nerve with on-demand electrical nerve block (OD-ENB). OD-ENB can be provided by an implantable capsule. Externally, at least a portion of the capsule can be constructed of a conductive membrane and the rest of the capsule comprises a biocompatible material. A blocking electrode contact, a return electrode contact, and a powering/communication component can be within the capsule. The blocking electrode contact can deliver a direct current (DC) through a portion of the conductive membrane to block conduction in the neural tissue to provide the OD-ENB. The return electrode contact can receive a return current from the neural tissue through another portion of the conductive membrane. The powering/communication component can communicate with one or more external components located external to the patient's body to receive a power signal. Notably the capsule has no internal battery. | 2020-09-17 |
20200289818 | VARIABLE CURRENT DENSITY SINGLE NEEDLE ELECTROPORATION SYSTEM AND METHOD - This invention comprises an improved electroporation electrode system comprising a single needle and a ring or donut shaped electrode wherein the difference in surface area of the electrodes provide for a substantial reduction of current density near the surface of the treated tissue and a more concentrated current density sufficient for electroporation only in tissues adjacent to the terminal portion of the single needle electrode. Thus, this invention provides for targeting specific tissue for electroporation and also should provide for lessening the sensation of electric current in the treated tissue. | 2020-09-17 |
20200289819 | SYSTEM, METHOD AND COMPUTER-ACCESSIBLE MEDIUM FOR TREATING CIRCULATING TUMOR CELLS IN THE BLOOD STREAM - An exemplary apparatus, can include, for example, a circulating tumor cell (CTC) treatment arrangement, a pump arrangement configured to circulate a fluid through the CTC treatment arrangement, and an electric field generator electrically connected to the CTC treatment arrangement, and configured to apply an electric field to the fluid circulating through the CTC treatment arrangement. The pump arrangement can be a peristaltic pump, which can be configured to continuously circulate the fluid through the CTC treatment arrangement. According to another exemplary embodiment of the present disclosure, method, system and computer-accessible medium can be provided for killing at least one circulating tumor cell (CTC). Using such exemplary embodiment, blood can be pumped from a body of a patient to an electroporation chamber inside of a CTC treatment arrangement. An electric field can be applied to the blood located in the electroporation chamber in order to kill the CTC. The electric field-applied blood can be pumped back into the body. | 2020-09-17 |
20200289820 | KIDNEY TREATMENT - Described is a low voltage, pulsed electrical stimulation device for controlling expression of klotho, a useful protein, by tissues. Also described are methods of enhancing expression of klotho in cells and treating a subject's kidneys. | 2020-09-17 |
20200289821 | LEADLESS PACING SYSTEM INCLUDING SENSING EXTENSION - A leadless pacing system includes a leadless pacing device and a sensing extension extending from a housing of the leadless pacing device. The sensing extension includes one or more electrodes with which the leadless pacing device may sense electrical cardiac activity. The one or more electrodes of the sensing extension may be carried by a self-supporting body that is configured to passively position the one or more electrodes proximate or within a chamber of the heart other than the chamber in which the LPD is implanted. | 2020-09-17 |
20200289822 | THERAPEUTIC MODULATION TO TREAT ACUTE DECOMPENSATED HEART FAILURE, AND ASSOCIATED SYSTEMS AND METHODS - Systems and methods for treating a patient having acute decompensated heart failure (ADHF) using electrical stimulation are disclosed. A representative method for treating a patient includes positioning an implantable signal delivery device proximate to a target location at or near the patient's spinal cord within a vertebral range of about T1 to about T12, directing an electrical therapy signal to the target location via the implantable signal delivery device, wherein the electrical signal has a frequency in a frequency range of from 1.2 kHz to 100 kHz to modulate one or more of the patient's sympathetic nerves and treat the patient's ADHF. | 2020-09-17 |
20200289823 | SYSTEMS AND METHODS FOR DELIVERING VAGAL NERVE STIMULATION - According to various method embodiments, a person is indicated for a therapy to treat a cardiovascular disease, and the therapy is delivered to the person to treat the cardiovascular disease. Delivering the therapy includes delivering a vagal stimulation therapy (VST) to a vagus nerve of the person at a therapeutically-effective intensity for the cardiovascular disease that is below an upper boundary at which upper boundary the VST would lower an intrinsic heart rate during the VST. | 2020-09-17 |
20200289824 | TELEMETRY COMMUNICATION SYSTEM FOR AN IMPLANTABLE MEDICAL DEVICE - The invention relates to a telemetry communication system for an implantable medical device ( | 2020-09-17 |
20200289825 | Actuated Electrode Lead in Minimally Invasive Cochlear Implant Surgery - An implantable electrode arrangement for a cochlear implant system is described. An electrode lead contains a lead structure control element configured to control a lead shape of the electrode lead between an insertion state wherein the electrode lead within a mastoid tunnel has a longitudinal lead axis lying entirely along the tunnel axis, and a post-insertion state wherein a facial recess portion of the electrode lead fitting within a limited diameter portion of the mastoid tunnel associated with a facial recess portion of the mastoid bone has a longitudinal lead axis along the tunnel axis, and a storage portion of the electrode lead fitting within an enlarged diameter portion of the mastoid tunnel lateral to the facial recess portion has a longitudinal lead axis coiled in a helical shape radially around the tunnel axis. | 2020-09-17 |