37th week of 2013 patent applcation highlights part 43 |
Patent application number | Title | Published |
20130236858 | SURROUNDING BIRD VIEW MONITORING IMAGE GENERATION METHOD AND TRAINING METHOD, AUTOMOBILE-SIDE DEVICE, AND TRAINING DEVICE THEREOF - A surrounding bird view image generation method for use in an automobile-side device of an articulated vehicle is provided. The articulated vehicle includes a first body part, a second body part and a connection part. The proceeding directions of the first and the second body parts form an angle. The image processing method includes the steps of: storing an angle-to-surrounding-image model table; detecting an angle and providing an angle measurement; accessing the angle-to-surrounding-image model table to obtain a selected angle and a selected surrounding image model corresponding to the angle measurement; capturing 6 adjacent images corresponding to the surrounding of the vehicle body by the image capturers disposed on the 6 surrounding sides of the articulated vehicle; obtaining a practical operating surrounding image by processing the first to the sixth images with the selected surrounding image model. | 2013-09-12 |
20130236859 | APPARATUS AND SYSTEM FOR APPLYING REMOVEABLE, SHEET MATERIAL ON A WALL - An apparatus and system for applying a removable, sheet material on a substrate. One example embodiment includes an applicator or roller device that is used to apply a temporary, removable sheet of material on walls to preview or sample the color of a ceiling, wall (interior or exterior), or room (or other surfaces) prior to painting a ceiling, wall, or room by placing of sample of paint on the removable sheet. | 2013-09-12 |
20130236860 | SYSTEM AND METHOD FOR TESTING PROGRAMMING SKILLS - The present embodiment discloses a test engine to evaluate a test taker's programming skills. The test engine includes at least one partial program logic module that defines a set of predefined conditions in relation to the solution to a problem, an input module that receives test taker input relating to the problem and an evaluation module that combines the predefined conditions and the test taker input to form a complete functionality to be evaluated and assigns a score based upon at least the correctness of the complete functionality. | 2013-09-12 |
20130236861 | PACKAGE FOR CONSUMABLE PRODUCTS - A package is provided for housing consumable products. Methods for teaching children to identify foods to consume and for identifying product brands are also provided. In a general embodiment, the present disclosure provides packages including a body defining a perimeter and at least one interior compartment for housing a consumable product. The perimeter alone, or the perimeter in conjunction with the compartments, forms a shape that is not a typical geometric shape and that is a recognizable shape to a child such as, for example, a ghost or a dog. | 2013-09-12 |
20130236862 | APPARATUS FOR DISPLAYING GENEALOGY INFORMATION - An apparatus and system are disclosed for displaying genealogy information. The apparatus includes a container. One or more first generation pieces fit together to form a first layer in the container. At least one first generation piece includes identity information of a person (“first generation person”). Each first generation person is related to a person (“original person”) through a genealogical relationship. One or more second generation pieces fit together to form a second layer in the container. At least one second generation piece includes identity information of a person (“second generation person”). Each second generation person is related to a first generation person identified on at least one of the first generation pieces through a genealogical relationship. | 2013-09-12 |
20130236863 | SYSTEM AND METHOD FOR PROVIDING TELEPHONY BASED MATHEMATIC TESTING - The present invention generally relates to testing methods. Specifically, the present invention relates to a computer implemented system and method for providing testing in one or more academic subjects over one or more telephone or audio/voice communication means. | 2013-09-12 |
20130236864 | Use of colored beads in an augmented simple abacus - The use of colored beads with an augmented simple abacus, adds an addition or expansion to the previous augmentations described in my previous patent which has the title: Augmented Simple Abacus With an Underlying Grid of Numbers or a Blank Sheet. And this invention has been given Publication No. US-2012-0028229-A1, and a Publication Date of: Feb. 1, 2012. | 2013-09-12 |
20130236865 | SYSTEMS AND METHOD FOR MODIFYING HUMAN BEHAVIOR USING AN AUDIO RECORDING DURING SLEEP - The invention provides a method or system for modifying behavior in a human subject using an audio recording during sleep. The audio recording includes positive suggestions for achieving a desired result recorded over background music. Binaural beats are incorporated into the background music. The positive suggestions are directed to the subconscious mind and address a specific goal the human subject wishes to achieve or a specific problem that the human subject wishes to overcome. The audio is pre-recorded and designed to be listened to by the human subject on a daily basis for a pre-determined period of time. The method includes a Guide that provides important information, recommendations, and key language terms for the human subject and/or caregiver for best results. It also provides Evaluation Forms to measure and track the progress and results throughout the process. | 2013-09-12 |
20130236866 | CHILDREN'S EXERCISE PLAY SET - A children's instructional floor exercise apparatus for developing physical, cognitive and social skills. The apparatus has a plurality of tiles that have an anatomy indicium and an independent tile orientation indicium. When the tiles are placed in a predetermined pattern and with each tile's orientation indicia indicating the same rotational orientation, the anatomy indicia correspond to a predetermined physical movement designed to exercise a specific muscle group and develop a specific physical skill. The apparatus may be provided with written instructions describing the desired tile pattern and physical movement. Multiple apparatus may be provided in a set so as to create an obstacle course of movements, with each obstacle designed to work with and complement other obstacles in the set to provide a well-rounded exercise routine. | 2013-09-12 |
20130236867 | BRAIN RE-TRAINING SYSTEM FOR AMBULATORY AND/OR FUNCTIONAL PERFORMANCE THERAPY - A simple and practical clinical system and method to objectively assess and evaluate patient status and progress in different aspects of gait and functional performance is provided in which a complete functional clinical program that emphasizes the functional parameters relevant to gait or functional performance, such as walking, sit to stand (STS), standing, weight shifting ability, stair-climbing, the heel to toe gait pattern, symmetry in weight bearing, and adequate limb loading patterns is possible in the clinics and at home. An objective therapy regimen personalized to the patient is loaded into a handheld device to guide the patient through the exercises and to monitor compliance. Various forms of encouraging feedback are provided to the patient during the sessions. The therapy regimen may be updated remotely based on the patient's performance. | 2013-09-12 |
20130236868 | TRAINING APPARATUS FOR GUIDING USER TO IMPROVE FITNESS - A processing system includes a memory storing tasks that define a physical exercise and a target value. The tasks are divided into categories of training requirements, and each category is linked to a progress status indicator. The processing system determines a progress status and retrieves a task from a category corresponding to the progress status; instructs the user to carry out a physical exercise; acquires measurement data generated during physical exercise; compares information acquired from the measurement data with the target value. Upon determining, on the basis of the comparison that the user reached the target value, the processing system stores a task indicator to indicate that the task was completed the progress status of the user has increased sufficiently as a result of completing the task, the processing system raises the progress status of the user, and retrieves a subsequent task. | 2013-09-12 |
20130236869 | SKILL JUDGING DEVICE, SKILL JUDGING METHOD AND STORAGE MEDIUM - Every time a performance action is played with a performance appliance, a state of each performance action is detected. A degree of variations of the states of the performance actions is detected by using a variations sensor and a degree of skill of the performance action is judged and notified based on the result detected by the variations sensor. | 2013-09-12 |
20130236870 | Online Interactive Practice System - An online, interactive practice system is provided, which allows users to practice skills and to learn about desired subjects using interactive, multimedia practice modules (tools) relating to desired subjects. The system includes a computer system in communication with a plurality of remote user devices via a network, a plurality of multimedia practice modules stored in a database of the computer system each including a lesson relating to a healthcare-related topic and allowing a user to practice a skill relating to the lesson, and a common directory structure for aggregating each of the plurality of multimedia practice modules. The system transmits a software module corresponding to a selected multimedia practice module to at least one of the plurality of remote user devices, for execution thereby to generate a virtual practice environment where the user can view a lesson and virtually practice a skill relating to the lesson. | 2013-09-12 |
20130236871 | METHOD AND SYSTEM FOR DELIVERING PATIENT SPECIFIC CONTENT - A method of providing patient specific content includes storing desired health related information; obtaining patient characteristics; obtaining health related information in accordance with the patient characteristics; and providing the obtained health related information to the patient. | 2013-09-12 |
20130236872 | Automatic Injection Training Device - Exemplary embodiments of the present disclosure provide reusable training automatic injection training devices, and components thereof, to simulate and/or mimic an operation of an actual automatic injection device. Exemplary embodiments of the training device can provide audible instructions, which can be in different languages, output from circuitry associated with the training device. Exemplary embodiment of the training device can be a self-contained and portable device that mimics a shape, size, and function of an actual automatic injection device without including a needle or any drug on board. Exemplary embodiments can be implemented to train a user on an operation and/or usage of an actual automatic injection device using embodiments of the automatic injection training devices so that a user can practice an autoinjection without injecting a therapeutic agent, such as a liquid drug, into a recipient | 2013-09-12 |
20130236873 | Sialendoscopy Demonstration Apparatus - Models, kits and methods useful in the demonstration of sialendoscopy devices and techniques are described. An exemplary demonstration apparatus comprises a support structure, an insert structure contacting the support structure, and a duct structure contacting the insert structure. The insert structure has a top surface defining a first opening and a bottom surface defining a second opening, and defines a channel with a first end in communication with the first opening and a second end in communication with the second opening. The duct structure comprises an elongate tubular member and has a first end in fluid communication with the first opening of the insert member, a second end, and defines a lumen extending from the first end to the second end. A portion of the duct structure is releasably disposed within the channel defined by the insert structure. | 2013-09-12 |
20130236874 | METHOD AND SYSTEM FOR PRODUCING AT LEAST ONE PATIENT-SPECIFIC SURGICAL AID - In an embodiment of the present invention, a method for producing at least one patient-specific surgical aid is described. A native patient tissue having at least one patient tissue surface of interest is provided. A moldable substance is placed into contact with at least a portion of the patient tissue surface of interest. An impression of the patient tissue surface of interest is maintained upon the moldable substance. The moldable substance is solidified into a patient-specific surgical aid. The patient-specific surgical aid is removed from the native patient tissue. A system for producing at least one patient-specific surgical aid is also disclosed. | 2013-09-12 |
20130236875 | CHOICE GENERATION METHOD FOR NUMERICAL MULTIPLE CHOICE QUESTION - A choice generation method for a numerical multiple choice question comprises steps: establishing a numerical multiple choice question, and obtaining a correct numerical answer of the numerical multiple choice question; determining the number of numerical choices for the numerical multiple choice question; and generating a plurality of the numerical choices either greater or smaller than the correct numerical answer according to a choice-answer relationship. The present invention applies to generate numerical choices for a numerical multiple choice question, and the generated numerical choices are different from the numerical correct answer. | 2013-09-12 |
20130236876 | Generating Visually Enhanced Question Topic Repetition Learning Content - A method performed by one or more processing devices, comprises: displaying, through a graphical user interface, test information in a layered structure; wherein a first layer in the layered structure is configured to display the test information following selection of a control in the graphical user interface; wherein a second layer in the layered structure is configured to display the test information following a display of the test information in the first layer; receiving, through the graphical user interface, one or more answers to one or more questions received in the test information; and generating, in response to receiving, information indicative of a test score. | 2013-09-12 |
20130236877 | SYSTEMS AND METHODS FOR PROVIDING EDUCATIONAL PRODUCTS AND SERVICES VIA CLOUD MASSIVE ONLINE OPEN COURSE - Provided are methods and systems for delivering educational products and services via a cloud massive online open course. Users may access the cloud massive online open course at any point of time using a networked client device. Educational resources are stored on a remote server of a cloud provider and are delivered to users over a network using cloud computing services. Users are also provided with tools for interaction within a cloud education environment. Along the learning process users of the cloud massive online open course may communicate with each other within the cloud education environment and share educational content with each other. Users' learning activity may be graded through online assessment. | 2013-09-12 |
20130236878 | Method for Testing and Developing Intelligence - The present invention is a method for testing and developing Artificial Intelligence, more particularly intelligence of machines, based on prediction of elements in human-generated documents. Essentially, if Artificial Intelligence can predict elements as effectively as human subjects, it can be considered an intelligent as human beings. | 2013-09-12 |
20130236879 | THREE-DIMENSIONAL, PREVASCULARIZED, ENGINEERED TISSUE CONSTRUCTS, METHODS OF MAKING AND METHODS OF USING THE TISSUE CONSTRUCTS - Embodiments of the present disclosure provide for three-dimensional (3D), prevascularized, engineered tissue constructs, 3D prevascularized engineered tissue models of cancer, and bioreactors and bioreactor arrays including the tissue constructs. The present disclosure also provides methods of making the tissue constructs, methods of using the tissue constructs, methods of drug discovery using the tissue constructs and/or cancer models, and the like. | 2013-09-12 |
20130236880 | DIRECT DETECTION OF UNAMPLIFIED HEPATITIS C VIRUS RNA USING UNMODIFIED GOLD NANOPARTICLES - A gold nanoparticle-based colorimetric assay kit for hepatitis C virus RNA that detects unamplified HCV RNA in clinical specimens using unmodified AuNPs and oligotargeter polynucleotides that bind to HCV RNA. A method for detecting hepatitis C virus comprising contacting a sample suspected of containing hepatitis C virus with a polynucleotide that binds to hepatitis C virus RNA and with gold nanoparticles, detecting the aggregation of nanoparticles, and detecting hepatitis C virus in the sample when the nanoparticles aggregate (solution color becomes blue) in comparison with a control or a negative sample not containing the virus when nanoparticles do not aggregate (solution color remains red). | 2013-09-12 |
20130236881 | THREE-DIMENSIONAL METAL-COATED NANOSTRUCTURES ON SUBSTRATE SURFACES, METHOD FOR PRODUCING SAME AND USE THEREOF - The invention relates to a method for producing column-shaped or conical nanostructures, wherein the substrate surface is covered with an arrangement of metal nanoparticles and etched, the nanoparticles acting as an etching mask and the etching parameters being set such that column structures or cone structures are created below the nanoparticles and the nanoparticles are preserved as a structural coating. | 2013-09-12 |
20130236882 | Micro-Devices for Improved Disease Detection - Among others, the present invention provides micro-devices for detecting or treating a disease, each comprising a first sorting unit capable of detecting a property of the biological subject at the microscopic level and sorting the biological subject by the detected property; a first detection unit capable of detecting the same or different property of the sorted biological subject at the microscopic level; and a first layer of material having an exterior surface and an interior surface, wherein the interior surface defines a first channel in which the biological subject flows from the first sorting unit to the first detection unit. | 2013-09-12 |
20130236883 | PROCESS OF DIRECTLY DETECTING AND IDENTIFYING A MICROORGANISM IN A BIOLOGICAL SAMPLE DILUTED IN AN ENRICHMENT BROTH - The present invention generally relates to the field of analysis for example biological analysis. More specifically, the present invention relates to a process of detecting at least one microorganism present in a sample placed in a closed container, said method comprising essentially the following steps:
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20130236884 | COMPOSITIONS FOR USE IN IDENTIFICATION OF ORTHOPOXVIRUSES - Oligonucleotide primers and compositions and kits containing the same for rapid identification of | 2013-09-12 |
20130236885 | MULTIPLE SEPARATION DEVICE AND METHOD OF SEPARATING BLOOD CANCER CELL - The present inventive concept provides a multiple separation device and a method of separating a blood cancer cell using the same. In the device and the method, a blood sample is put in a fine channel and then cancer cells can be separated according to the type of cancer by controlling a flow velocity of the blood or a magnetic force of ferromagnetic pattern. | 2013-09-12 |
20130236886 | Phage Phi 29 DNA Polymerase Chimera - A DNA polymerase chimera comprising an amino-terminal (N-terminal) region encoding a φ29 type DNA polymerase and a carboxyl-terminal (C-terminal) region comprising at least one HhH domain which are bound by a connecting amino acid sequence is disclosed along with and the use thereof for replicating, amplifying or sequencing a template DNA. Also disclosed is a method for replicating, amplifying or sequencing a deoxyribonucleic acid with a DNA polymerase chimera and kits for carrying out the methods. | 2013-09-12 |
20130236887 | Method and Apparatus for Measuring Analyte Transport Across Barriers - The present invention includes a method and apparatus for measuring the transport of analytes through a cell barrier. | 2013-09-12 |
20130236888 | ENZYME SUBSTRATE COMPRISING A FUNCTIONAL DYE AND ASSOCIATED TECHNOLOGY AND METHODS - Enzyme substrates and associated technology of the present invention are provided. An enzyme substrate of the invention may comprise a biologically functional fluorescent dye and an enzyme-specific substrate moiety attached in such a way that the functionality of the functional dye is diminished. An enzymatic reaction may cleave at least a portion of the substrate moiety from the enzyme substrate to provide a more functional product dye. This product dye may be nonfluorescent or weakly fluorescent, in general, and relatively fluorescent, in a particular condition, such as when bound to a partner biological molecule or an assembly of partner biological molecules. An enzyme substrate of the present invention may thus be useful in fluorescence detection, and/or in any of a variety of useful applications, such as the detection of enzymatic activity in a cell-free system or in a living cell, the screening of drugs, or the diagnosis of disease. | 2013-09-12 |
20130236889 | Vascularization Inhibitors - This invention provides a therapeutic agent for inhibiting neovascularization, a therapeutic agent for a solid cancer, a therapeutic agent for a disease pathologically caused by neovascularization, and a therapeutic agent for repairing a tissue comprising as the effective ingredient, a substance that potentiates the action of CXCR4. | 2013-09-12 |
20130236890 | NOVEL METHOD FOR ANALYZING CIRCULATING TUMOR CELLS OF A PATIENT FOR THE PRESENCE OF METASTASIS-INITIATING CELLS - This invention relates to a novel method for analyzing circulating tumor cells of a patient for the presence of metastasis-initiating cells. The method comprises the step of detecting cells exhibiting the simultaneous presence of c-MET, CD44 and CD47. The invention further relates to novel kits, novel methods for treating patients, and novel bifunctional analytes. | 2013-09-12 |
20130236891 | METHOD AND COMPOSITION FOR THE TREATMENT, PREVENTION, AND DIAGNOSIS OF CANCER CONTAINING OR DERIVED FROM CANCER STEM CELLS - The invention provides a method and composition for the treatment, prevention, and diagnosis of cancer containing or derived from cancer stem cells. | 2013-09-12 |
20130236892 | MEANS AND METHODS FOR THE DETECTION OF A PREDISPOSITION OF A FEMALE SUBJECT TO RECURRENT PREGNANCY LOSS (RPL), PREECLAMPSIA (PE) AND/OR FETAL GROWTH RESTRICTION (FGR) - The present invention relates to a method for diagnosing or detecting a predisposition of a female subject to recurrent pregnancy loss (RPL), preeclampsia (PE) and/or fetal growth restriction (FGR), comprising examining the human annexin A5 (ANXA5) promoter in a sample obtained from the intended biological father or the biological father and to detect nucleotide exchanges therein, wherein the presence of the nucleotide exchanges defined in (i) and/or (ii) indicates a predisposition of said female subject to recurrent pregnancy loss (RPL), preeclampsia (PE) and/or fetal growth restriction (FGR). The present invention also relates to a nucleic acid sequence comprising a human annexin A5 (ANXA5) promoter, which promoter comprises specific nucleotide exchanges defined herein, for use in the methods disclosed herein. The present invention further relates to a kit for use in the diagnostic methods disclosed herein. | 2013-09-12 |
20130236893 | METHOD OF DETECTING TYPE II DIABETES - A single-nucleotide polymorphism in the UBE2E2 locus or C2CD4A-C2CD4B locus is analyzed and type II diabetes is examined based on the results of the analysis. | 2013-09-12 |
20130236894 | MUTATIONS IN SPTLC2 GENE ASSOCIATED WITH SENSORY NEUROPATHY - Described are methods and kits for identifying a subject at risk of, or having, a sensory neuropathy related disease, such as sensory neuropathies. In particular, the disclosure is based on the determination of mutations in the SPTLC2 gene causing sensory neuropathies. | 2013-09-12 |
20130236895 | METHOD OF SEQUENCE DETERMINATION USING SEQUENCE TAGS - The invention is directed to the use of sequence tags to improve sequence determination of amplicons of related sequences, particularly large and complex amplicons, such as those comprising recombined nucleic acids encoding immune receptor molecules. In one aspect, sequence reads having the same sequence tags are aligned after which final base calls are determined from a (possibly weighted) average base call from sequence read base calls at each position. Similarly, in another aspect, sequence reads comprising series of incorporation signals are aligned by common sequence tags and base calls in homopolymer regions are made as a function incorporation signal values at each “flow” position. | 2013-09-12 |
20130236896 | E. COLI O157:H7 SPECIFIC ASSAY - Disclosed are assays, methods and kits for the specific detection of | 2013-09-12 |
20130236897 | Anaplasma FAMILY MEMBERS CAUSE A NUMBER OF BLOOD-BORNE DISEASES - A method of assaying for the presence of | 2013-09-12 |
20130236898 | Anaplasma FAMILY MEMBERS CAUSE A NUMBER OF BLOOD-BORNE DISEASES - A method of assaying for the presence of | 2013-09-12 |
20130236899 | Methods And Compositions For Detecting Multiple Analytes With A Single Signal - Compositions, methods, and devices for the detection of multiple analytes with a single signal are provided. | 2013-09-12 |
20130236900 | REAGENT FOR THE DISRUPTION OF CELL MATERIAL HAVING A COMPLETELY INTEGRATED INTERNAL STANDARD - The present invention relates to a reagent for the disruption of cell material, containing an internal standard that is completely integrated into the reagent for control and evaluation of the completeness of disruption of the cell material and subsequent steps, comprising a step selected from sample preparation, extraction, enrichment, isolation, purification, reverse transcription, amplification and detection of the cell components obtained from the disrupted cells, or a combination of a plurality or all of these steps. | 2013-09-12 |
20130236901 | MICROFLUIDIC DEVICE FOR PRODUCTION AND COLLECTION OF DROPLETS OF A FLUID - A microfluidic device and method for producing and collecting single droplets of a first fluid, the device including a microfluidic platform having at least a droplet microchannel wherein is produced a flow of single droplets of the first fluid dispersed in a second fluid immiscible with the first fluid, the droplet microchannel having at least one inlet extremity and at least one outlet extremity for distributing the flow of droplets, the device further including:
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20130236902 | Collection and Methods For Its Use - The present disclosure enables collections of variable heavy chain and variable light chain pairs comprising, in part, germline protein sequences that are pre-selected for functional properties relevant to developability, wherein the collections may be used to select against any antigen using, for example, phage display. | 2013-09-12 |
20130236903 | AUTOMATIC NECLEIC ACID PURIFICATION APPARATUS AND METHOD FOR AEROSOL-PROTECTING - Disclosed is an automatic nucleic acid purification apparatus which can prevent pollution due to aerosol generated from a biological sample containing high concentration target nucleic acid when the biological sample containing the high concentration target nucleic acid is mixed with other biological sample containing low concentration target nucleic acid or not containing the target nucleic acid. Further, disclosed is an automatic nucleic acid purification apparatus which can be applied to all kinds of nucleic acid purification equipments for purifying a plurality of biological samples using a magnet rode or a multi-pipette block moving in two or three axial directions, and which can minimize pollution due to the aerosol generated from the biological sample containing high concentration target nucleic acid and also can obtain accurate results. | 2013-09-12 |
20130236904 | METHOD FOR SCREENING FOR MATERIALS FOR PROMOTING THE DIFFERENTIATION OF SKIN CELLS - The present invention relates to a method for screening for materials for promoting the differentiation of skin cells, comprising: a step of treating skin cells with a test material; and a step of checking the relative degree of the expression of the DUOX 1 gene in the skin cells treated with the test material in the previous step. The present invention also relates to a kit for screening for materials for promoting the differentiation of skin cells, comprising a device for checking the relative degree of expression of the DUOX 1 gene in skin cells. The present invention also relates to a composition which contains, as an active ingredient, a material for increasing the expression of the DUOX 1 gene to promote the differentiation of skin cells, moisturize the skin, improve skin barrier function, or alleviate or treat symptoms of atopic dermatitis. | 2013-09-12 |
20130236905 | ASSAY FOR IDENTIFYING ANTIGENS THAT ACTIVATE B CELL RECEPTORS COMPRISING NEUTRALIZING ANTIBODIES - The invention described herein provides a method for screening pathogenic viral envelope proteins and protein complexes to identify protein constructs with enhanced effectiveness as vaccine immunogens. The method is carried out by (i) expressing of a membrane-bound isotype of an antibody that has the same binding activity and specificity of an antibody that is known, or identified, to bind and neutralize the targeted virus, and that has the capacity to activate signaling pathways down-stream of B cell receptor ligand binding and activation—a modified neutralizing antibody-based B cell receptor; (ii) exposing the cell to antigen; and (iii) assay for signaling downstream of B cell receptor activation. The present invention also provides the antigens identified using the as say described herein, and neutralizing antibodies derived by immunization with the antigens identified using the assay described herein. | 2013-09-12 |
20130236906 | DIAGNOSTIC METHOD FOR THE DETECTION OF CELLS EX VIVO - The present invention provides an ex vivo method for detecting a subset of cells with a specific binding domain, the binding domain, diagnostic compositions comprising the binding domain, and kits comprising the binding domain. | 2013-09-12 |
20130236907 | COMPOSITION, APPARATUS, AND METHOD FOR SEPARATING AN ANALYTE FROM A SAMPLE - An analyte is separated from a fluid sample by introducing the sample into a cartridge having a sample port and a first flow path extending from the sample port. The first flow path includes an extraction chamber containing a solid support for capturing the analyte from the sample. The cartridge has a second flow path for eluting the captured analyte from the extraction chamber, the second flow diverging from the first flow path after passing through the extraction chamber. The sample is forced to flow through the extraction chamber and into a waste chamber, thereby capturing the analyte with the solid support as the sample flows through the extraction chamber. The captured analyte is then eluted from the extraction chamber by forcing an elution fluid to flow through the extraction chamber and along the second flow path. | 2013-09-12 |
20130236908 | METHOD FOR PREDICTING A NEED FOR RENAL REPLACEMENT THERAPY (RRT) - A method for predicting a need for Renal Replacement Therapy (RRT) in a patient comprises: determining a concentration of pi glutathione S transferase-(πGST) in a first urine sample from the patient; and wherein a need for RRT is predicted when the πGST concentration is determined to be elevated in comparison to a patient without kidney injury. The method according to the invention can further comprise detecting for the presence of risk factors for RRT in a patient, the risk factors including elevated serum creatinine concentration, type I diabetes, type II diabetes, hypertension, dyslipidemia, hyperglycaemia, proteinuria and hypoalbuminemia. | 2013-09-12 |
20130236909 | Enzyme Triggered Redox Altering Chemical Elimination (E-Trace) Immunoassay - The present invention is directed to electronic methods of detecting target analytes such that upon binding of the target analyte a shift in electrochemical potential is seen. This assay relies on the use of an electroactive moiety (“EAM”) that is attached to an electrode and comprises a self-immolative moiety, whose presence gives the EAM a first E0, and whose absence, upon irreversible cleavage gives the EAM a second E0. This difference is detected, and if such change occurs, it is an indication of the presence of a target analyte. | 2013-09-12 |
20130236910 | TEST METHOD AND APPARATUS - In a method for testing a patient with a test apparatus for a plurality of diseases using a specimen collected from the subject, if the subject is determined to be positive for one of the plurality of diseases, a test result indicating the positive is outputted from the test apparatus without waiting for completion of the testing of the other diseases. | 2013-09-12 |
20130236911 | HEMOKININ-1 RECEPTOR AND HEMOKININ-1-DERIVED PEPTIDE - The present invention provides a peptide having antagonist activity against SP, pain control activity, anti-inflammation activity, and anti-pruritic activity. The present invention further provides a method for searching for a therapeutic agent for pain, a therapeutic agent for inflammation, and a therapeutic agent for pruritus using G protein coupled receptor (GPR) 83, which is an HK-1 specific receptor. | 2013-09-12 |
20130236912 | Use Of Quinolinone Derivatives As A Research Tool - The present invention relates to the use of quinolinone derivatives of general formula (I), ligands of the Smo receptor or of related receptors which target a binding site of the receptor which is different from the known ligand binding sites, as research tools for identifying modulators of the Smo receptor or of related receptors, characterizing the Hedgehog signalling pathway and diagnosis; the invention also relates to kits containing said derivatives of general formula (I). | 2013-09-12 |
20130236913 | SEROLOGICAL MARKERS FOR DETECTING COLORECTAL CANCER AND THEIR APPLICATION FOR INHIBITING COLORECTAL CANCER CELLS - Embodiments relate to serological markers for detecting the colorectal cancer and applications of the serological markers. A phospholipid scramblase (PLSCR1), a stomatin-like protein 2 (STOML2) or a transport protein Sec61β (SEC61β) increases expression in the blood at the earlier stage of the colorectal cancer. Detecting the expression of the PLSCR1, STOML2 or SEC61β protein or an induced autoantibody of each protein in a blood sample is used to diagnose the colorectal cancer. Moreover, the serological marker improves the detection efficiency and the sensitivity in detecting the colorectal cancer and is used to predict the prognosis. The serological markers are applied in preparing a detection device or inhibiting the growth of the colorectal cancer cells. | 2013-09-12 |
20130236914 | DEVICES AND METHODS FOR ANALYSIS OF SAMPLES WITH DEPLETION OF ANALYTE CONTENT - A system and method for determining the presence and/or concentration of one or more analytes in a sample that comprises a fluid, the system comprising a solid substrate comprising a sample inlet or inlets and one or more analyte determination flow paths, each analyte determination flow path comprising a defined beginning and a defined terminus and comprising at least one capture zone containing a capture agent for an analyte, the capture agent or agents being immobilized along a portion of the flow path or paths, the flow path or paths being designed so that the one or more analytes are depleted from the sample and bound in a non-linear manner to the portion of the flow path or paths containing immobilized capture agent or agents, producing an analyte depletion end region for each analyte between the beginning and the terminus of the analyte determination flow path. | 2013-09-12 |
20130236915 | METHOD OF INSPECTING PERIODONTAL DISEASE CAUSING BACTERIA USING OUTER MEMBRANE VESICLE AND MEASURING APPLIANCE OF THE SAME - The invention provides a method of inspecting bacteria by using an outer membrane vesicle of the bacteria, which is useful for easily diagnosing a periodontopathic bacteria with high precision. An outer membrane vesicle of bacteria to be detected is previously arranged in a measuring portion of a measuring appliance, a specimen material collected from a test subject is brought into contact with the measuring portion, and an anti-outer membrane vesicle antibody corresponding to the outer membrane vesicle in the specimen material is detected on the basis of an antigen antibody reaction. A measuring appliance for executing the inspecting method of the bacteria is structured such that the outer membrane vesicle of the bacteria to be detected is previously arranged in the measuring portion. | 2013-09-12 |
20130236916 | D-DIMER, TROPONIN, AND NT-PROBNP FOR PULMONARY EMBOLISM - The present invention relates to a method of diagnosing acute pulmonary embolism (PE) in a subject including a) determining the amount of fibrin-fibrinogen degradation products, in particular D-dimer in a sample of the subject; b) determining the amount of a natriuretic peptide in a sample of the subject; c) determining the amount of a cardiac troponin in a sample of the subject; and d) comparing the amounts determined in steps a) to c) to reference amounts, thereby establishing the diagnosis. Included is also a method of deciding on a therapy of a subject diagnosed with PE and a method of monitoring the therapy. | 2013-09-12 |
20130236917 | ALBUMIN-BOUND PROTEIN/PEPTIDE COMPLEX AS A BIOMARKER FOR DISEASE - Methods and kits provide for diagnosis and prognosis of ischemia by using biomarkers comprising albumin-bound protein/peptide complex (ABPPC). | 2013-09-12 |
20130236918 | SANDWICH ASSAY FOR IMMUNOSUPPRESSANT DRUGS - Methods are disclosed for determining an immunosuppressant drug in a sample suspected of containing an immunosuppressant drug. The method includes providing in combination in a medium the sample, a first monoclonal antibody for the immunosuppressant drug, and a second monoclonal antibody for the immunosuppressant drug. The second monoclonal antibody binds to a portion of the immunosuppressant drug other than the portion to which the first monoclonal antibody binds to the immunosuppressant drug. The medium is incubated under conditions for binding of the first monoclonal antibody and the second monoclonal antibody to the immunosuppressant drug. The medium is examined for the presence of an immunocomplex comprising the immunosuppressant drug, the first monoclonal antibody and the second monoclonal antibody. The presence and/or amount of the immunocomplex indicates the presence and/or amount of the immunosuppressant drug in the sample. | 2013-09-12 |
20130236919 | METHODS AND COMPOSITIONS FOR DIAGNOSING AND TREATING MOOD DISORDERS - The present invention relates to methods of diagnosing, prognosing or treating diseases or disorders in which elevated or reduced levels of Aβ protein, including Aβ | 2013-09-12 |
20130236920 | POST PROTEIN HYDROLYSIS REMOVAL OF A POTENT RIBONUCLEASE INHIBITOR AND THE ENZYMATIC CAPTURE OF DNA - The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample. | 2013-09-12 |
20130236921 | Manufacture of Active Highly Phosphorylated Human Lysosomal Sulfatase Enzymes and Uses Thereof - This invention provides compositions of active highly phosphorylated lysosomal sulfatase enzymes, their pharmaceutical compositions, methods of producing and purifying such lysosomal sulfatase enzymes and compositions and their use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the lysosomal sulfatase enzyme. | 2013-09-12 |
20130236922 | COPPER(I)-ION SELECTIVE FLUORESCENT PROBE, METHOD FOR PREPARING THE SAME, METHOD FOR DIAGNOSING MALIGNANT DISEASE AND DIAGNOSIS KIT USING THE PROBE - The present disclosure relates to a copper (I) ion-selective fluorescent probe, a method for preparing the same, and a method for diagnosing malignant disease and a diagnosis kit using the probe. The fluorescent probe according to the present disclosure is capable of detecting free copper (I) ions inside cells for a long time with high selectivity and sensitivity for copper (I) ion, with a penetration depth longer than 90 μm in living cells and tissues and without the problems of mistargeting and photobleaching. Accordingly, since a biological sample can be imaged for a long period of time with high resolution without damage, presence of malignance disease in the target biological sample can be diagnosed faster, more accurately and more easily. | 2013-09-12 |
20130236923 | Characteristic Parameters of Cells and Tissue from Quantitative Phase Imaging - Methods mapping a characteristic parameter of a specimen, such as a scattering mean free path and a scattering anisotropy factor, based on a quantitative phase shift measurement. The methods have steps of using spatial light interference microscopy (SLIM) to determine a quantitative phase shift as a function of position in a sample, and applying a generalized scatter-phase transformation to derive at least one of a scattering mean free path (MFP), a scattering anisotropy factor, and a thickness-independent parameter as a function of position in the sample. In some cases, the sample may be a slice of tissue or a cell. | 2013-09-12 |
20130236924 | COMPLIANT MULTI-WELL PLATE - Multi-well plate ( | 2013-09-12 |
20130236925 | DETECTION OF RATE CHANGES IN SYSTEMATIC OSCILLATIONS OF METABOLIC PATHWAYS BY MONITORING ISOTOPE RATIOS - The methods described herein are based on the observation that oscillations in breath isotope ratio data can be used for the purpose of identifying an “unhealthy” state in an organism such as a human. Described herein are methods of determining the state of health of an individual, such as the transition from healthy to infected, by identifying changes in oscillation modes in breath isotope ratio data. Changes in the frequency and/or amplitude of the oscillation modes are correlated with the heath of the individual. The methods can advantageously be used to provide information about the health of an individual in shorter periods of time than previous methods. | 2013-09-12 |
20130236926 | Device For Spraying A Reagent For Fast Microbiological Analysis - The device for spraying a reagent onto a support ( | 2013-09-12 |
20130236927 | Multi-Chambered Tissue Containment System for Molecular and Histology Diagnostics - A container for storing a biological sample is disclosed. The container includes a first chamber having a sidewall extending between an open end and a closed end, defining a first chamber interior adapted to receive a sample holder therein. The container also includes a second chamber having a sidewall extending between an open end and a closed end, defining a second chamber interior adapted to subsequently receive the sample holder therein. The second chamber interior is in fluid isolation from the first chamber interior. A removable closure encloses at least one of the open end of the first chamber and the open end of the second chamber while the sample holder is disposed within one of the first chamber interior and the second chamber interior. A first fluid may be disposed within the first chamber interior, and a second different fluid may be disposed within the second chamber interior. | 2013-09-12 |
20130236928 | ROMIDEPSIN-BASED TREATMENTS FOR CANCER - The invention provides an improved process for preparing romidepsin. The process involves producing, purifying, or storing romidepsin under conditions that prevent the formation of undesired adducts. Purifying romidepsin at an apparent pH lower than approximately 6.0 (e.g., between an apparent pH of 4.0 and 6.0) has been discovered to prevent the reduction of the disulfide bond of romidepsin and the subsequent formation of dimerized, oligomerized, or polymerized adducts. The invention also provides pharmaceutical compositions of monomeric romidepsin free of dimerized, oligomerized, or polymerized adducts. | 2013-09-12 |
20130236929 | IMMORTALIZED AVIAN CELL LINES AND USE THEREOF - The present invention relates to specific immortalized avian cell lines expressing telomerase reverse transcriptase (TERT), and exhibiting distinct biologics production patterns. More particularly, the present invention relates to immortalized avian cell line capable of either amplifying Flaviviridae but not capable of amplifying Vaccinia virus strain Copenhagen (VV-COP) nor Modified Vaccinia virus Ankara (MVA), or capable of amplifying both Flaviviridae and Poxviridae. The invention further relates to the use of said immortalized avian cell lines and related methods for producing biologics, including viruses and proteins. | 2013-09-12 |
20130236930 | PROCESS FOR PRODUCING IGF-1 POLYPEPTIDES - A process is described for producing a polypeptide heterologous to | 2013-09-12 |
20130236931 | SEQUENCE DIVERSITY GENERATION IN IMMUNOGLOBULINS AND OTHER PROTEINS - An in vitro system for generating sequence, and thus structural, diversity in proteins is described. The system can be constructed using appropriately selected nucleic acid molecules that encode regions of a selected protein or proteins and recombination signal sequences (RSS). The selected protein(s) can be, for example, immunoglobulin (Ig) V, D, J and/or C regions, regions of a non-immunoglobulin (non-Ig) protein, or a combination of Ig regions and non-Ig regions. Assembly of such appropriately selected components and their introduction into suitable recombination-competent host cells allows for recombination between the RSS sequences and introduction of sequence and structural diversity into the protein(s). | 2013-09-12 |
20130236932 | POLYPEPTIDES WITH PERMEASE ACTIVITY - The invention relates to a polypeptide having a mutation at one or more position corresponding to T219 of SEQ ID NO: 55, wherein the polypeptide has at least 50% sequence identity with SEQ ID NO: 55, and wherein the polypeptide has permease activity. | 2013-09-12 |
20130236933 | Methods for Producing a Fermentation Product from Lignocellulose-Containing Material - The present invention provides a method for producing a fermentation product from lignocellulose-containing material, a method for converting lignocellulose-containing material into a hydrolyzate comprising mono- and oligo-saccharides, and a method for treating lignocellulose-containing material, all of which comprise the step of mixing an acid pre-treated lignocellulose-containing material and an alkaline pre-treated lignocellulose-containing material. The present invention further provides a fermentation product made according to the method for producing a fermentation product. | 2013-09-12 |
20130236934 | RECOMBINANT BACTERIUM FOR L-HOMOSERINE PRODUCTION - The present invention encompasses a recombinant bacterium that is capable of producing L-homoserine and methods of using the bacterium for producing L-homoserine. | 2013-09-12 |
20130236935 | EXTRACTION SOLVENTS DERIVED FROM OIL FOR ALCOHOL REMOVAL IN EXTRACTIVE FERMENTATION - In an alcohol fermentation process, oil derived from biomass is hydrolyzed into an extractant available for in situ removal of a product alcohol such as butanol from a fermentation broth. The glycerides in the oil can be catalytically (e.g., enzymatically) hydrolyzed into free fatty acids, which form a fermentation product extractant having a partition coefficient for a product alcohol greater than a partition coefficient of the oil of the biomass for the product alcohol. Oil derived from a feedstock of an alcohol fermentation process can be hydrolyzed by contacting the feedstock including the oil with one or more enzymes whereby at least a portion of the oil is hydrolyzed into free fatty acids forming a fermentation product extractant, or the oil can be separated from the feedstock prior to the feedstock being fed to a fermentation vessel, and the separated oil can be contacted with the enzymes to form the fermentation product extractant. The fermentation product extractant can be contacted with a fermentation broth for in situ removal of a product alcohol. | 2013-09-12 |
20130236936 | A SYSTEM AND METHOD FOR SEPARATING HIGH VALUE BY-PRODUCTS FROM GRAINS USED FOR ALCOHOL PRODUCTION - Systems and methods are provided for separating high value by-products, such as oil and/or germ, from grains used for alcohol production. In one embodiment, a method for separating by-products from grains used for alcohol production includes, subjecting milled grains to liquefaction to provide a liquefied starch solution including fiber, protein, and germ. The germ is separated from the liquefied starch solution. The separated germ is ground, e.g., to a particle size less than 50 microns, to release oil to provide a germ/oil mixture. Then, prior to fermentation, the oil is separated from the germ/oil mixture to yield an oil by-product. The pH of the germ/oil mixture can be adjusted to about 8 to about 10.5 and/or cell wall breaking enzymes or chemicals may be added to help release oil from the germ. In one example, the oil yield is greater than 1.0 lb/Bu. | 2013-09-12 |
20130236937 | Algal Thermoplastics, Thermosets, Paper, Adsorbants and Absorbants - Provided are biomass-based materials and valuable uses of microalgal biomass including: (i) acetylation of microalgal biomass to produce a material useful in the production of thermoplastics; (ii) use of triglyceride containing microalgal biomass for production of thermoplastics; (iii) combination of microalgal biomass and at least one type of plant polymer to produce a material useful in the production of thermoplastics; (iv) anionization of microalgal biomass to form a water absorbant material; (v) cationization of microalgal biomass, and optional flocculation, to form a water absorbant material; (vi) crosslinking of anionized microalgal biomass; (vii) carbonization of microalgal biomass; and (viii) use of microalgal biomass in the making of paper. | 2013-09-12 |
20130236938 | BIODIESEL FUEL PRODUCTION, SEPARATION METHODS AND SYSTEMS - The present invention provides for a method for treatment of fats, oils and grease (FOG) for separation of target products and/or the efficient production of biodiesel while reducing disposal of solid or liquid waste matter into landfills or water treatment facilities. | 2013-09-12 |
20130236939 | METHOD OF ORGANIC ACID FERMENTATION BY RUMEN FLUID USING CELLULOSE-CONTAINING WASTE MATTER - The present application provides a method for producing organic acid, such as acetic acid, propionic acid, butyric acid, or another high-quality raw material designed for methane fermentation and obtained by converting waste paper and other forms of cellulose-based biomass to organic acid, wherein said method comprising a step for reacting rumen fluid collected from a ruminant animal with cellulose-containing waste matter. This method provides the effective use of cellulose-containing waste matter, which is a high-quality fermentation resource. | 2013-09-12 |
20130236940 | METHOD FOR THE OXIDATION OF ORGANIC COMPOUNDS - A method is described for the oxidation of organic compounds in which the organic compound that is to be oxidized is brought to reaction in an aqueous solution in the presence of cytochrome P 450, and wherein perfluorinated organic compound is added to the aqueous reaction mixture as activator. | 2013-09-12 |
20130236941 | Integrated Biorefinery - Systems and methods for producing bioproducts are shown. The systems and methods herein can be configured and used in an integrated biorefinery. The integrated biorefinery may comprise a sugar production facility such as a sugar mill, a production facility for one or more bioproduct(s) such as butanol, and optionally an ethanol production facility employing the system and method. | 2013-09-12 |
20130236942 | PRODUCTION OF ACETYL-COENZYME A DERIVED ISOPRENOIDS - Provided herein are compositions and methods for the heterologous production of acetyl-CoA-derived isoprenoids in a host cell. In some embodiments, the host cell is genetically modified to comprise a heterologous nucleotide sequence encoding an acetaldehyde dehydrogenase, acetylating (ADA, E.C. 1.2.1.10) and an MEV pathway comprising an NADH-using HMG-CoA reductase. In some embodiments, the host cell is genetically modified to comprise a heterologous nucleotide sequence encoding an ADA and an MEV pathway comprising an acetoacetyl-CoA synthase. In some embodiments, the genetically modified host cell further comprises one or more heterologous nucleotide sequences encoding a phosphoketolase and a phosphotransacetylase. In some embodiments, the genetically modified host cell further comprises a functional disruption of the native PDH-bypass. The compositions and methods described herein provide an energy-efficient yet redox balanced route for the heterologous production of acetyl-CoA-derived isoprenoids. | 2013-09-12 |
20130236943 | Method for production of isoprenoid compounds - The present invention is directed to variant squalene synthase enzymes, including | 2013-09-12 |
20130236944 | METHODS FOR THE INACTIVATION OF ANTIBIOTICS - The invention relates to methods for inactivating antibiotics in the environment. The invention further relates to the use of a laccase, a lipase or a cellulase for inactivation of antibiotics. It also relates to compositions to decontaminate the polluted environment and to prevent the pollution of the environment by inactivating antibiotics from waste and wastewater effluents before they reach the environment. | 2013-09-12 |
20130236945 | Fusion Protein Having Factor VII Activity - A fusion protein comprising factor VII (FVII) and transferrin according to the present invention has an improved specific activity of FVII compared to existing FVII fusion proteins comprising other fusion partners than transferrin, and thus can be effectively used in a therapy using FVII. | 2013-09-12 |
20130236946 | MEGANUCLEASE VARIANTS CLEAVING A DNA TARGET SEQUENCE FROM THE MOUSE ROSA26 LOCUS AND USES THEREOF - An I-CreI variant, wherein one of the two I-CreI monomers has at least two substitutions, one in each of the two functional subdomains of the LAGLIDADG core domain situated respectively from positions 26 to 40 and 44 to 77 of I-CreI, said variant being able to cleave a DNA target sequence from the mouse ROSA26 locus. Use of said variant and derived products for the engineering of transgenic mice and recombinant mouse cell lines expressing an heterologous protein of interest. | 2013-09-12 |
20130236947 | SUBSTRATE HAVING ROD-LIKE MOLECULES ON SURFACE THEREOF AND METHOD FOR PRODUCING THE SAME - A substrate having rod-like molecules on a surface thereof including: a substrate in which a pattern including a convex portion with a flat upper surface is formed on at least a portion thereof; and a plurality of rod-like molecules, which are formed into rod-like shape, are aligned in line in a direction crossing a molecular length direction of each of the rod-like molecules an the upper surface of the convex portion, and have liquid crystalline states, wherein the molecular length L | 2013-09-12 |
20130236948 | RECOMBINANT MICROORGANISMS AND USES THEREOF - The present invention provides live recombinant microorganisms such as prokaryote organisms, particularly enterobacteria, preferably | 2013-09-12 |
20130236949 | COMPOSITION AND METHOD FOR BIOREMEDIATION OF DEICING FLUIDS - The present invention is a kit and method for bioremediation of deicing fluids containing glycol. Using a combination | 2013-09-12 |
20130236950 | METHOD AND APPARATUS TO REDUCE THE CARBON DIOXIDE CONTENT IN THE EARTH'S ATMOSPHERE - The object of the present invention is an atmospheric bioremediation system focused to reduce the Carbon Dioxide content in the Earth's atmosphere. The disclosed system includes an apparatus to distribute iron in low oxidation states such as zero or plus two trough out the photic region of high nutrients low clorophylls (HNLC) oceans over a period of time. This special apparatus is needed to provide a slow and continuous release of the iron to prevent premature precipitation. It has been shown that microalgae growth is usually initiated by the addition of iron and its sustained feed in water whose only limiting nutrient to prevent algal growth is iron itself. It has also been shown that southern oceans are a possible large batch area where iron is the limiting nutrient. | 2013-09-12 |
20130236951 | Microalgae for Removal of Carbon Dioxide Generated from Biogas and Biogas Electric Generator - The present invention relates to biogas and biogas electric generator and a biogas electricity generation method by use microalgae for removal of carbon dioxide generated from biogas and biogas electric generator. The electric generator integrates biogas production and purification, microalga culture, electricity generation, heat recycling and others into a unit volume, and, during microalgae culturing, uses carbon dioxide contained in biogas and that produced from electricity generation as a carbon source for photosynthesis to reduce the carbon dioxide contained in the biogas and the electricity generation exhaust gas, thereby attaining the goal of zero carbon emission. | 2013-09-12 |
20130236952 | SYSTEM FOR PROCESSING BIOMASS - A system for processing biomass using anaerobic digestion includes an anaerobic acidification reactor having an inlet for biomass and an outlet for acidified biomass, and an anaerobic settling chamber having an inlet for receiving the acidified biomass from the anaerobic acidification reactor wherein an acidified liquid biomass and a sludge biomass is formed. The anaerobic settling chamber includes a first outlet for the acidified liquid biomass, a second outlet for the sludge biomass and a third outlet for gaseous biogas effluent. The system further includes an anaerobic methane synthesis reactor for anaerobic microbial conversion of acidified liquid biomass into biogas and processed liquid biomass, having an inlet for receiving the acidified liquid biomass and a first outlet for gaseous biogas effluent and a second outlet for the processed liquid biomass. | 2013-09-12 |
20130236953 | METHOD AND APPARATUS FOR LIGNOCELLULOSE PRETREATMENT USING A SUPER-CELLULOSE-SOLVENT AND HIGHLY VOLATILE SOLVENTS - Embodiments of the present invention overcome the well-known recalcitrance of lignocellulosic biomass in an economically viable manner. A process and a system are provided for the efficient fractionation of lignocellulosic biomass into cellulose, hemicellulose, and lignin. The cellulose and hemicellulose thus obtained are highly amorphous and can be readily converted into highly concentrated mixtures of five and six carbon sugars using known methods. Typical yields of sugars exceed 100 grams of sugars per liter of sugar solution. Other products, such as alcohols, can easily be prepared according to methods of the invention. The modest process conditions and low solvent/solid ratios of some embodiments of the invention require relatively low capital and processing costs. | 2013-09-12 |
20130236954 | Method for Isolation of Transcription Termination Sequences - The invention relates to efficient, high-throughput methods, systems, and DNA constructs for identification and isolation of transcription termination sequences. The invention relates further to specific terminator sequences identified by said methods isolated from rice. | 2013-09-12 |
20130236955 | CELL PASSAGE DEVICE - A cell passage device for automatic passage of a suspension of biological tissue or cells from a first culture vessel into one or more additional culture vessels includes a sampling unit, a dosing unit, at least one reservoir for fluid, a pressure recipient and a fluid block. The sampling unit removes the suspension from the first culture vessel and includes at least one ascending tube and at least one pressure tube. An ascending tube receives the suspension. A pressure tube pressurizes the first culture vessel. The ascending tube and pressure tube are inserted into the first cell culture vessel and sealable with the first cell culture vessel in a pressure-proof manner. The dosing unit doses the suspension into additional culture vessel(s). The fluid block has horizontally oriented fluid channels and valves assigned them, making fluid connections with the sampling unit, dosing unit, at least one reservoir and the pressure recipient. | 2013-09-12 |
20130236956 | NUCLEIC ACID FRAGMENTS FROM A RIBOSOMAL PROTEIN PROMOTER FOR ENHANCING GENE EXPRESSION - The present invention relates to nucleic acid fragments and constructs comprising genomic nucleotide sequences from the promoter region of a 60S ribosomal protein L32 gene (RPL32), for the production of a gene product of interest in a eukaryotic, preferably mammalian, host cell in the presence of a stringent selectable marker. The invention further relates to host cells comprising the nucleic acid constructs, to methods for generating the host cells and to methods for producing a gene product of interest using the host cells. | 2013-09-12 |
20130236957 | EXPRESSION VECTOR AND METHODS OF PRODUCING HIGH LEVELS OF PROTEINS - A process for high expression of protein of interest using an expression vector. The process comprises at least the following regulatory elements:
| 2013-09-12 |