| 36th week of 2008 patent applcation highlights part 51 |
| Patent application number | Title | Published |
|---|
| 20080214622 | Substituted Triazole Derivatives As Oxytocin Antagonists - The present invention relates to a class of substituted triazoles of formula (I) with activity as oxytocin antagonists, uses thereof, processes for the preparation thereof and compositions containing said inhibitors. These inhibitors have utility in a variety of therapeutic areas including sexual dysfunction, particularly premature ejaculation (P.E.). | 2008-09-04 |
| 20080214623 | N-(2,2-Dimethylpropyl)-6- -3-Pyridinecarboxamide - The present invention relates to a novel compound, processes for its preparation, compositions comprising the same and its use in the treatment of condition or diseases mediated by p38 kinase activity. | 2008-09-04 |
| 20080214624 | Fungicidal Composition Comprising a Pyridylmethylbenzamide Derivative and a Thiazolecarboxamide Derivative - A composition comprising at least a pyridylmethylbenzamide derivative of general formula (1) | 2008-09-04 |
| 20080214625 | Roflumilast for the Treatment of Diabetes Mellitus - The invention relates to the use of Roflumilast and/or Roflumilast N-Oxide for the treatment of diabetes mellitus and accompanying disorders thereof. The invention additionally relates to combinations of Roflumilast and/or Roflumilast N-Oxide with other active agents for the treatment of diabetes mellitus. | 2008-09-04 |
| 20080214626 | Methods for prevention and treatment of diseases causes by hypertension - A method for the prevention and/or treatment of a disease caused by hypertension comprising administering to a mammal, such as a human, in need thereof pharmaceutically effective amounts of (5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2′-(1H-tetrazol-5-yl(biphenyl-4-yl]methyl]imidazol-5-carboxylate and a calcium channel blocker which is amlodipine or amlodipine besylate. | 2008-09-04 |
| 20080214627 | DIACYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES IN MAMMALIAN SYSTEMS VIA AN ECDYSONE RECEPTOR COMPLEX - The present invention relates to non-steroidal ligands for use in nuclear receptor-based inducible gene expression system, and a method to modulate exogenous gene expression in which an ecdysone receptor complex comprising: a DNA binding domain; a ligand binding domain; a transactivation domain; and a ligand is contacted with a DNA construct comprising: the exogenous gene and a response element; wherein the exogenous gene is under the control of the response element and binding of the DNA binding domain to the response element in the presence of the ligand results in activation or suppression of the gene. | 2008-09-04 |
| 20080214628 | Compounds Capable of Activating Cholinergic Receptors - Compounds incorporating aryl substituted olefinic amine are provided. Representative compounds are (4E)-N-methyl-5-(3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-pyrimidinyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-methoxy-3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(6-amino-5-methyl-3-pyridyl)-4-penten-2-amine, (2R)-(4E)-N-methyl-5-(3-pyridyl)-4-penten-2-amine, (2R)-(4E)-N-methyl-5-(5-isopropoxy-3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-bromo-3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-ethoxy-3-pyridyl)-4-penten-2-amine, (2S)-(4E)-N-methyl-5-(3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-isopropoxy-3-pyridyl)-4-penten-2-amine and (2S)-(4E)-N-methyl-5-(5-isopropoxy-3-pyridyl)-4-penten-2-amine. | 2008-09-04 |
| 20080214629 | CONTROLLED RELEASE COMPOSITIONS OF TIZANIDINE - The present invention relates to a novel controlled release formulations of tizanidine. The invention also provides methods of using novel controlled release formulations of tizanidine to treat a patient. | 2008-09-04 |
| 20080214630 | Desferrithiocin polyether analogues - Compounds represented by structural formulas described herein, such as Structural Formula (I): | 2008-09-04 |
| 20080214631 | USE OF RILUZOLE FOR THE TREATMENT OF MULTIPLE SCLEROSIS - Methods and compositions for the treatment of multiple sclerosis comprising riluzole (6-(trifluoromethoxy)-benzothiazolamine) are disclosed herein. | 2008-09-04 |
| 20080214632 | Parasiticidal Compositions - The present invention relates to products comprising a macrocylic lactone and an amidine, which products are suitable for controlling parasites, in particular ectoparasites, on animals. | 2008-09-04 |
| 20080214633 | Alpha-form or beta-form crystal of acetanilide derivative - To provide novel crystals useful as an ingredient for the production of a diabetes remedy. The invention is concerned with α-form crystal and β-form crystal of (R)-2-(2-aminothiazol-4-yl)-4′-[2-[(2-hydroxy-2-phenylethyl)amino]ethyl]acetanilide. The α-form crystal does not exhibit hygroscopicity and has stability such that it can be used as a medicine, and is useful for mass synthesis in the industrial production. The β-form crystal does not relatively exhibit hygroscopicity and is also useful as a production intermediate of the α-form crystal. | 2008-09-04 |
| 20080214634 | Active substance combinations having insecticidal and acaricidal properties - The present invention relates to novel insecticidally and acaricidally active compound combinations of N | 2008-09-04 |
| 20080214635 | Modulation of pathogenicity - The present invention relates to the use of compounds of the general Formula (I): | 2008-09-04 |
| 20080214636 | Glycyrrhetinic Acid-30-Amide Derivatives and Their Use - The present invention relates to the field of a medicine for treating diseases associated with inflammation, immunity or infection, and in particular, to glycyrrhetinic acid-30-amide derivatives of general formula I and their preparation, and a pharmaceutical composition containing the same. Said derivatives and composition exhibit anti-inflammatory, analgesic, anti-allergic, cough-preventing, liver-protecting and anti-viral properties, | 2008-09-04 |
| 20080214637 | Process for the Synthesis of Tetrazoles - A process for the synthesis of tetrazol derivative has been developed which starts from a tetrazole derivative where acidic hydrogen atom has been replaced by a protecting group and the deprotection is performed with a catalytic amount of organic acid and can proceed in an aqueous solvent. | 2008-09-04 |
| 20080214638 | Anthranilic Acid Derivatives Active as the Hm74a Receptor - Therapeutically active anthranilic acid derivatives of Formula (I) or of Formula (Ia) wherein R, R | 2008-09-04 |
| 20080214639 | Leuprolide acetate and acetylcholinesterase inhibitors/NMDA receptor antagonists for the treatment of alzheimer's disease - Methods of treating, mitigating, slowing the progression of, or preventing Alzheimer's Disease include administration of gonadotropin-releasing hormone analogues in combination with acetylcholinesterase inhibitors and/or N-methyl-D-aspartate receptor antagonists. | 2008-09-04 |
| 20080214640 | Thrombopoietin mimetics - Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative. | 2008-09-04 |
| 20080214641 | Chemical compounds 572 - Compounds of formula (I): | 2008-09-04 |
| 20080214642 | Fungicidal N-Benzyl-5-Hydroxy-5-Phenylpryrazolines, Processes For Their Preparation and Compositions Comprising Them - N-benzoyl-5-hydroxy-5-phenylpyrazolines of the formula I | 2008-09-04 |
| 20080214643 | FUSED HETEROCYCLIC SUCCINIMIDE COMPOUNDS AND ANALOGS THEREOF, MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION - Fused cyclic compounds, methods of using such compounds in the treatment of nuclear hormone receptor-associated conditions such as cancer and immune disorders, and pharmaceutical compositions containing such compounds. | 2008-09-04 |
| 20080214644 | 2-(1H-INDOLYLSULFANYL)-BENZYL AMINE DERIVATIVES AS SSRI - The present invention relates to 2-(1H-indolylsulfanyl)-benzyl amine derivatives of general formula (I): | 2008-09-04 |
| 20080214645 | USES OF 2-(1H-INDOLYLSULFANYL)-BENZYL AMINE DERIVATIVES AS SSRIS - The present invention relates to uses of 2-(1H-indolylsulfanyl)-benzyl amine derivatives of general formula (I): | 2008-09-04 |
| 20080214646 | Novel Nsaids Possessing a Nitric Oxide Donor Diazen-1-Ium-1,2-Diolate Moiety - This invention provides a prodrug that help arthritis patients without increasing cardiovascular and gastrointestinal risk. A novel group of hybrid nitric oxide-releasing non-steroidal anti-inflammatory drugs (NO-NSAIDs), moiety attached via a one -carbon methylene spacer to the carboxylic acid group of the traditional NSAIDs aspirin, ibuprofen and indomethacin were synthesized. The ester prodrugs showed equipotent anti-inflammatory activities in vivo to that of the parent aspirin, ibuprofen and indomethacin. The simultaneous release of parent drug and nitric oxide from the NO- prodrugs constitutes a potentially beneficial property for the prophylactic prevention of thrombus formation and adverse cardiovascular events such as stroke and myocardial infarction. Data acquired in an in vivo ulcer index (UI) assay showed that this group of ester prodrugs in which no lesions were observed when compared to the parent drugs at equivalent doses. Accordingly, these hybrid NO-NSAID prodrugs possessing a diazen-1-ium-1,2-diolate moiety, represents a new approach for the rational design of anti-inflammatory drugs with reduced gastric ulcerogenicity. | 2008-09-04 |
| 20080214647 | SUBSTITUTED INDOLE ACID DERIVATIVES AS INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1) - This invention provides compounds of the formula: | 2008-09-04 |
| 20080214648 | Hiv Prodrugs Cleavable by Cd26 - The present invention provides new prodrugs which are conjugates of a therapeutic compound and a peptide wherein the conjugate is cleavable by dipeptidyl-peptidases, more preferably by CD26, also known as DPPIV (dipeptidyl aminodipeptidase IV). The present prodrugs have the formula | 2008-09-04 |
| 20080214649 | Compositions and Therapeutic Use of N-Acetyl Aldosamines and N-Acetylamino Acids - Embodiments relate to compositions and use of compositions comprising amino acids and/or N-acetylamino acids for systemic administration to a mammal. Systemic administration is believed to alleviate or improve symptoms or syndromes associated with nervous, vascular, musculoskeletal, or cutaneous systems. | 2008-09-04 |
| 20080214650 | Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel process for preparing other forms - The present invention provides novel forms of atorvastatin designated Forms VI, VIII, IX, X, XI and XII and novel processes for their preparation as well as processes for preparing atorvastatin Forms I, II, IV, V and amorphous atorvastatin. | 2008-09-04 |
| 20080214651 | Crystalline forms of [R-(R*, R*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid calcium salt (2:1) - Novel crystalline forms of [R—(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemi calcium salt designated Form V, Form VI, Form VII, Form VIII, Form IX, Form X, Form XI, Form XII, Form XIII, Form XIV, Form XV, Form XVI, Form XVII, Form XVIII, and Form XIX are characterized by their X-ray powder diffraction, solid-state NMR, and/or Raman spectroscopy are described, as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, and Alzheimer's disease. | 2008-09-04 |
| 20080214652 | Methods of treating hyperlipidemia - The current invention relates to methods for treating hyperlipidemia in mammals, including humans. More specifically, the current invention relates to the use of retinoid or retinoid derivative that is able to act as an antagonist or inverse agonist of a retinoid receptor to treat hyperlipidemia. | 2008-09-04 |
| 20080214653 | Methods and Compositions for the Prevention and Treatment of Kindney Disease - The invention provides compositions for preventing or treating kidney disease and improving kidney function comprising at least two ingredients selected from the group consisting of antioxidants and mitochondrial cofactors in amounts sufficient for preventing or treating kidney disease or for improving kidney function and methods for preventing and treating kidney disease or improving kidney function comprising administering such compositions to an animal susceptible to or suffering from kidney disease or impaired kidney function. In a preferred embodiment, the composition is admixed with one or more food ingredients to produce a food composition useful for preventing or treating kidney disease and improving kidney function, particularly in senior animals. | 2008-09-04 |
| 20080214654 | Substituted Benzyloxy-Phenylmethylamide Derivatives - The present invention relates to novel substituted benzyloxy-phenylmethylamide derivatives, processes for their preparation, and their use in medicaments, especially for the prophylaxis and treatment of diseases associated with Cold Menthol Receptor 1 (CMR-1) activity, in particular for the treatment of urological diseases or disorders, such as detrusor overactivity (overactive bladder), urinary incontinence, neurogenic detrusor oeractivity (detrusor hyperflexia), idiopathic detrusor overactivity (detrusor instability), benign prostatic hyperplasia, and lower urinary tract symptoms; chronic pain, neuropathic pain, postoperative pain, rheumatoid arthritic pain, neuralgia, neuropathies, algesia, nerve injury, ischaemia, neurodegeneration, stroke, and inflammatory disorders such as asthma and chronic obstructive pulmonary (or airways) disease (COPD). | 2008-09-04 |
| 20080214655 | Paclitaxel enhancer compounds - Disclosed is a compound represented by the Structural Formula (I): | 2008-09-04 |
| 20080214656 | Compounds With Diphenoyl-Structure For the Treatment of Immune Diseases - A composition comprising compounds with a diphenoyl (DP 5 structure for preventing or treating an immune disease and a prophylactic or therapeutic method for the immune disease based on the application of the compounds are provided. The compounds with the DP structure increase the number and activity of regulatory T cells involved in regulating an accelerated immune system. Also, the compounds can be an effective prophylactic or therapeutic agent for various immune diseases including transplantation rejection, graft-versus-host diseases, autoimmune diseases, and hypersensitive inflammatory diseases. | 2008-09-04 |
| 20080214657 | TOPICAL AVERMECTIN FORMULATIONS AND METHODS FOR ELIMINATION AND PROPHYLAXIS OF SUSCEPTIBLE AND TREATMENT-RESISTANT STRAINS OF HEAD LICE - An avermectin-based topical formulation is disclosed which is useful for prevention and treatment of head lice (Pediculus humanus | 2008-09-04 |
| 20080214658 | Composition Comprising Isoorientin for Suppressing Histamine - The present invention relates to a pharmaceutical composition for the prevention or treatment of diseases mediated by excessive histamine comprising naturally-derived isoorientin, a use of isoorientin for the manufacture of a medicament for the prevention or treatment of diseases mediated by excessive histamine, and a method for preventing or treating diseases mediated by excessive histamine comprising administering a therapeutically effective amount of isoorientin to a subject. The composition, use and method of the present invention show excellent histamine suppression effects, and so can be used for the prevention or treatment of various kinds of allergic disease, atopic disease, inflammatory disease, skin disease, hyperacidity and nervous system disorder. | 2008-09-04 |
| 20080214659 | Stage-Specific Reduction of LUTS in Prostate Disease - Methods and compositions are presented in which catechin-containing compositions have statistically significant and strong therapeutic effect in the treatment of LUTS wherein such compositions are stage-specifically administered to a patient diagnosed with HG-PIN and optional coexistent BPH. | 2008-09-04 |
| 20080214660 | Compounds and Methods for the Inhibition of the Expression of VCAM-1 - This invention is in the area of methods and compositions for the inhibition of the expression of VCAM-1 and, in particular, for the treatment of diseases mediated by VCAM-1, including cardiovascular and inflammatory diseases. | 2008-09-04 |
| 20080214661 | Process To Obtain Dibenzylbutyrolactonic, Tetrahydrofuranic Lignans And Their Synthetic And Semi-Synthetic Derivatives, Their Analgesic And Anti-Inflammatory Activities, Topical And/Or Systemic Formulations Containing Said Lignans And Their Respective Therapeutic Method - A process to obtain dibenzylbutyrolactonic lignans from (-)-cubebin, isolated from a | 2008-09-04 |
| 20080214662 | METHODS FOR THE TREATMENT OF DEMENTIA BASED ON APO E GENOTYPE - This invention relates to methods to prevent worsening of and/or to improve cognitive functioning and behaviour problems in patients with dementia by means of ApoE genotyping to guide the use of AChEI drugs, including rivastigimine. Also included are kits for determining ApoE4 status and recommended treatment strategy. | 2008-09-04 |
| 20080214663 | Levodopa dimethyl-substituted diester prodrugs compositions, and methods of use - Levodopa dimethyl-substituted diester prodrugs pharmaceutical, compositions comprising levodopa dimethyl-substituted diester prodrugs, and methods of using such prodrugs and pharmaceutical compositions for treating diseases such as Parkinson's disease are provided. | 2008-09-04 |
| 20080214664 | ANESTHETIC SPRAY COMPOSITION - An anesthetic spray composition suitable for application to the back of the throat comprising a topical anesthetic and a mucoadhesive polymer. | 2008-09-04 |
| 20080214665 | Novel Approach to Anti-Microbial Host Defense with Molecular Shields with Lipoxin Compounds - Methods to cause tissue, such as mucosal cells, to express increased amounts of bactericidal permeability increasing protein (BPI) are described. The BPI inducing agents include, for example, lipoxin compounds. | 2008-09-04 |
| 20080214666 | Products and Methods Related to Mono-Methyl Branched-Chain Fatty Acids - Disclosed are genes and proteins related to the biosynthesis and function of mono-methyl branched-chain fatty acids (mmBCFA) in eukaryotes, as well as the functions of mmBCFA in eukaryotic organisms. Also disclosed are methods to regulate the biosynthesis and function of mmBCFA in an organism, methods to use the valuable targets associated with mmBCFA biosynthesis and function as therapeutic agents and to screen for pharmaceuticals and nutraceuticals, or to investigate or screen for regulators of metabolism, growth, development, and reproduction in eukaryotes. The present invention also includes highly specific and useful animal models for mmBCFA biosynthesis and function that can be used to explore pharmaceutical applications of the mmBCFA-involved biological processes. | 2008-09-04 |
| 20080214667 | Elongase Gene and Uses Thereof - The subject invention relates to the identification of a gene involved in the elongation of polyunsaturated fatty acids containing unsaturation at the carbon 9 position (i.e., “Δ9-elongase”) and to uses thereof. In particular, Δ9-elongase may be utilized, for example, in the conversion of linoleic acid (LA, 18:2n-6) to eicosadienoic acid (EDA, 20:2n-6). The production of dihomo-γ-linolenic acid (DGLA, 20:3n-6) from eicosadienoic acid (EDA, 20:2n-6), and arachidonic acid (AA, 20:4n-6) from dihomo-γ-linolenic acid (DGLA, 20:3n-6) is then catalyzed by Δ8-desaturase and Δ5-desaturase, respectively. AA or polyunsaturated fatty acids produced therefrom may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics. | 2008-09-04 |
| 20080214668 | USE OF RETINOIDS TO TREAT HIGH BLOOD PRESSURE AND OTHER CARDIOVASCULAR DISEASE - This invention provides methods of treating a disease in a mammal where the disease is characterized by a symptom ameliorated by inhibition of cellular calcium influx. The methods involve administering to the mammal an effective amount of a retinoid and a pharmacologically acceptable excipient. | 2008-09-04 |
| 20080214669 | Composition and Method For Treating Hyperpigmented Skin - An improved cosmetic and dermatological composition and a method for treating hyperpigmented skin is disclosed. The composition demonstrates an enhanced ability to lighten mammalian skin color, and is nontoxic and nonirritating. The composition comprises a hydroxycinnamic acid or a methoxycinnamic acid dissolved in a compound having one or more hydroxy groups, like a monoC | 2008-09-04 |
| 20080214670 | Therapeutic Malonic Acid/Acetic Acid C60 Tri-Adducts of Buckminsterfullerene and Methods Related Thereto - Disclosed and claimed herein are e,e,e malonic acid/acetic acid tri-adduct of buckminsterfullerene of the general formula C | 2008-09-04 |
| 20080214671 | Dicarbonic Acid Derivatives, Metastasis Inhibitors and Agents Increasing Chemotherapeutic Activity of Anti-Tumor Preparations, Method for Enhancing the Cytostatic Efficiency and Metastasis Process Inhibiting Method - The invention relates to dicarbonic acid derivatives and concerns dicarbonic acid monooxydamines and dioxydamides, which are physiologically active substances and can be used as low-toxic and non-toxic agents for enhancing the anti-tumor and anti-metastasis effects of known cytostatics (cyclophosphane and cisplatin) in cytostatic chemotherapy of tumors. | 2008-09-04 |
| 20080214672 | Treatment of Asthma with Aryl Sulfonamides - The present invention relates to compounds that modulate various chemokine receptors. These compounds are useful for treating asthma. | 2008-09-04 |
| 20080214673 | Acetylene Derivatives - The invention provides compounds of formula (I) | 2008-09-04 |
| 20080214674 | ACYLHYDRAZONE DERIVATIVES AND THE USE THEREOF IN THE INHIBITION, REGULATION AND/OR MODULATION OF KINASE SIGNAL TRANSDUCTION - Acylhydrazone derivatives of the formula (I) are SGK inhibitors and can be used for the treatment of SGK-induced diseases and conditions, such as diabetes, obesity, metabolic syndrome (dyslipidaemia), systemic and pulmonary hypertonia, cardiovascular diseases and renal diseases, generally in any type of fibrosis and inflammatory process. In which R | 2008-09-04 |
| 20080214675 | Hydroxybenzoic Acid Amides and the Use Thereof For Masking Bitter Taste - The use is described of hydroxybenzoic acid amides having formula (I)
| 2008-09-04 |
| 20080214676 | DI-FLUORO CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS - The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S, and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them. | 2008-09-04 |
| 20080214677 | Chitosan-Silicon Dioxide Coprecipitate and Use as Excipient in Solid Dosage Forms - Chitosan silicon dioxide coprecipitate composition, method of production thereof, pharmaceutical composition comprising the chitosan silicon dioxide coprecipitate composition and use of the chitosan silicon dioxide coprecipitate composition for manufacturing a sustained or immediate release formulation. | 2008-09-04 |
| 20080214678 | Biopesticide Comprising a Composition Rich in Diallyl Polysulphides - The present invention relates to compounds based on diallyl polysulfides, and to biopesticides comprising said compositions. The invention also relates to the use of biopesticides based on said compositions rich in diallyl polysulfides for the effective insecticidal activity thereof in relation to a large number of insects. | 2008-09-04 |
| 20080214679 | TREATED BIODIESEL GLYCERIN - Disclosed are compositions that include treated biodiesel glycerin. The disclosed compositions may be utilized as soil-amendments for controlling pests, weeds and for enhancing growth of plants. The biodiesel glycerin utilized in the disclosed compositions may be treated by one or more steps including neutralization, heating, refluxing, condensing, and distilling. | 2008-09-04 |
| 20080214680 | Application of arsenic as a cancer prevention agent - Arsenic in drinking water at levels between 25 and <75 μg/L is cancer protective, compared to levels between 0 and <25 μg/L and levels at or above 75 μg/L. Methods are presented to decrease the cancer rate or not increase the cancer rate, for specific cancers and for cancers in general, based on this observation. | 2008-09-04 |
| 20080214681 | TASTE REDUCING COMPOSITIONS AND RELATED METHODS - A method includes contacting a surface in an oral cavity with a first composition capable of reducing a taste of a selected material, and orally administering a second composition separate from the first composition, the second composition including the selected material. The selected material can include a drug, and/or the second composition can further include a drug. In some embodiments, the first and second compositions are included in a kit. | 2008-09-04 |
| 20080214682 | METHODS OF TREATING PNEUMONIC PLAGUE - The present invention relates to methods of treating pneumonic plague. More specifically, the present invention relates to methods of using plasmin or Pla inhibitors to treat pneumonic plague. | 2008-09-04 |
| 20080214683 | Rapid Low-Foam Wetting Agents for Hydrophobic Surfaces - The present invention relates to the use of surfactants of the general formula (I) | 2008-09-04 |
| 20080214684 | Process for Dissolution of Highly Fluorinated Ion-Exchange Polymers - Highly fluorinated ion-exchange polymers achieve dissolution in aqueous tetrahydrofuran at lower pressures and temperatures than in other solvents, with few or no side products being formed. | 2008-09-04 |
| 20080214685 | Multibrached Polymer and Method for Producing the Same - The present invention provides a multibranched polymer represented by the following formula (I), and a method for producing the multibranched polymer: | 2008-09-04 |
| 20080214686 | PROCESS FOR PRODUCTION OF ZEOLITE FILM - A process for producing a zeolite membrane comprising a seed crystal forming step of placing, in a pressure-resistant vessel, a seeding sol containing silica, water and a structure-directing agent and a support in a state that the support is immersed in the seeding sol and heating the heat-resistant vessel to form a zeolite seed crystal on the surface of the support, and a membrane formation step of allowing the zeolite seed crystal to grow to form a zeolite membrane on the surface of the support. In the seed crystal forming step, the molar ratio of water/silica in the seeding sol is set 10 to 50 and the heating of the pressure-resistant vessel is conducted at 90 to 130° C. The crystal c-axis of the present zeolite membrane is oriented in a direction vertical to the surface of the support and its thickness is uniform. | 2008-09-04 |
| 20080214687 | Cross Linking Treatment of Polymer Membranes - Methods of forming a hydrophilic porous polymeric membrane which include preparing a porous polymeric membrane from a polymer blend which typically contains a hydrophobic non crosslinkable component (e.g. PVdF) and a component which is cross-linkable (for instance, PVP) and treating said porous polymeric membrane under cross linking conditions to produce a modified membrane with greatly improved water permeability and hydrophilic stability. Cross linking condition include chemical (e.g. peroxodisulfate species), thermal or radiation and/or combinations thereof. Non cross linked material may be washed out if desired. | 2008-09-04 |
| 20080214688 | SILICONE RUBBER SPONGE COMPOSITION - A silicone rubber sponge composition comprising (A) an organopolysiloxane, (B) a non-cyano organic azo blowing agent which is thermally decomposable to cause thickening or curing of component (A), (C) an azodicarbonamide or dinitrosopentamethylenetetramine blowing agent, and (D) a curing agent is crosslinkable and expandable with atmospheric hot air. The composition makes it possible to freely control the blowing magnification and the cell size of the resulting sponge, enabling to form a fully expanded silicone rubber sponge with crosslinked surface. The sponge free of cyano compounds is least toxic. | 2008-09-04 |
| 20080214689 | Manufacturing method and foaming manufacturing method of polymethyl methacrylate/silica composite material - A manufacturing method and a foaming manufacturing method of polymethyl methacrylate/silica composite material are disclosed. At first, synthesize silica by a sol-gel process. Then, prepare polymethyl methacrylate/silica composite material by bulk polymerization. At last, prepare polymethyl methacrylate/silica foam nanocomposite material from polymethyl methacrylate/silica composite material by a foaming method. | 2008-09-04 |
| 20080214690 | Grafted Material, and Method of Manufacturing the Same - There is provided a technique for introducing grafted side chains having a narrow molecular weight distribution onto a molded organic polymer substrate, for example polyolefin substrate, while maintaining the form of the substrate. One aspect of the present invention relates to a method of manufacturing a grafted material, comprising the steps of (a) irradiating an organic polymer substrate with ionizing radiation, and then bringing a polymerizable monomer and a polymerization initiating group-introducing agent into contact with the substrate, thus introducing grafted side chains having polymerization initiating groups on ends thereof onto trunk polymer of the substrate, and (b) then bringing a polymerizable monomer into contact with the substrate, thus causing the grafted side chains to grow. | 2008-09-04 |
| 20080214691 | Low-viscosity allophanates containing actinically curable groups - A process for preparing binders containing allophanate groups which contain, at the oxygen atom of the allophanate group that is bonded via two single bonds, organic radicals with activated groups capable of participating in a polymerization reaction with ethylenically unsaturated compounds on exposure to actinic radiation; the process includes reacting A) one or more compounds containing uretdione groups with B) one or more OH-functional compounds which contain groups capable of participating in a polymerization reaction with ethylenically unsaturated compounds on exposure to actinic radiation, and C) optionally further NCO-reactive compounds, and D) in the presence of one or more compounds containing phenoxide groups, as catalysts. The binders can be used in preparing coatings, coating materials, coating compositions, adhesives, printing inks, casting resins, dental compounds, sizes, photoresists, stereolithography systems, resins for composite materials and sealants. | 2008-09-04 |
| 20080214692 | OXIDATION RESISTANT HOMOGENIZED POLYMERIC MATERIAL - The present invention relates to methods for making oxidation resistant homogenized polymeric materials and medical implants that comprise polymeric materials, for example, ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making antioxidant-doped medical implants, for example, doping of medical devices containing, cross-linked UHMWPE with vitamin E by diffusion and annealing the antioxidant doped UHMWPE in a super critical fluid, and materials used therein. | 2008-09-04 |
| 20080214693 | Integrated Coating Material System Based on Uv-A-Curable Solventborne Coating Materials, Process for Producing it, and Use Thereof - An integrated coating material system comprising
| 2008-09-04 |
| 20080214694 | Waterborne Curable Resin Composition - To provide a waterborne curable resin composition that is advantageous for environmental protection measures, can be applied without use of a film-forming assistant and can improve the dispersion stability of the emulsion, and also improve physical properties of the coat such as curability, durability, and stain resistance. | 2008-09-04 |
| 20080214695 | Biocompatible crosslinked polymers with visualization agents - Biocompatible crosslinked polymers, and methods for their preparation and use, are disclosed in which the biocompatible crosslinked polymers are formed from water soluble precursors having electrophilic and nucleophilic functional groups capable of reacting and crosslinking in situ. Methods for making the resulting biocompatible crosslinked polymers biodegradable or not are provided, as are methods for controlling the rate of degradation. The crosslinking reactions may be carried out in situ on organs or tissues or outside the body. Applications for such biocompatible crosslinked polymers and their precursors include controlled delivery of drugs, prevention of post-operative adhesions, coating of medical devices such as vascular grafts, wound dressings and surgical sealants. Visualization agents may be included with the crosslinked polymers. | 2008-09-04 |
| 20080214696 | COMPOSITIONS AND METHODS FOR RESISTING SOIL EROSION & FIRE RETARDATION - Compositions and methods for concomitantly resisting fire and soil erosion. The compositions comprise an aqueous mixture of a polymer mixed with an organic material. The polymer preferably comprises polyacrylamide or a copolymer of polyacrylamide having anionic functional groups. The organic material comprises either cellulose, mulch and/or seed and mulch. The methods of the present invention comprise providing or forming an aqueous mixture of the compositions of the present invention and applying them to an area of land sought to be provided with soil erosion and/or fire resistant properties. | 2008-09-04 |
| 20080214697 | Reactive organo-modified inorganic particles and biodegradable hybrid material containing the same - A reactive organo-modified inorganic particle. Inorganic particles are modified with functional groups through chemical bonding, ionic bonding, hydrogen bond or complex formation. The functional groups of organo-modified inorganic particle can react with monomer or oligomer of biodegradable materials to facilitate crosslinking and functionalization, thus improving physical properties of the inorganic particle-biodegradable hybrid materials. | 2008-09-04 |
| 20080214698 | Polymer Blends Including Surface-Modified Nanoparticles and Methods of Making the Same - The present invention relates to the use of surface-modified nanoparticles to alter the morphology and microstructure of polymer blends. The addition of surface modified nanoparticles to polymer blends comprised of immiscible polymers facilitates the uniform distribution of the dispersed phase of the polymer blend. In an embodiment, the present invention relates to a polymer blend comprising (1) a continuous phase comprising at least one polymer, monomer or oligomer, and a plurality of surface-modified nanoparticles, having a particle diameter of less than about 100 nanometers, distributed in the continuous polymer phase; and (2) a dispersed phase comprising at least one polymer, monomer or oligomer, wherein the continuous polymer phase and the dispersed polymer phase are immiscible. | 2008-09-04 |
| 20080214699 | PROCESS FOR PRODUCING COMPATIBILIZED POLYMER BLENDS - A process is provided for producing a compatibilized polymeric blend. A first thermoplastic polymer and a reactive moiety are provided to a progressive melt kneading apparatus. The reactive moiety comprises a first reactive group capable of reacting with the first thermoplastic polymer but not a second polymer and a second reactive group capable of reacting with the second polymer but not the first polymer. The first thermoplastic polymer and the reactive moiety are then melt kneaded so that the first reactive group reacts with the first thermoplastic polymer and the second reactive group is grafted to the first thermoplastic polymer, forming a molten self-compatibilizer. A molten second polymer is then provided. The molten self-compatibilizer is melt kneaded with the molten second polymer so that the second reactive group reacts with the second polymer to form a compatibilized polymeric blend. Also provided are articles formed from the compatibilized polymer blend. | 2008-09-04 |
| 20080214700 | Natural Rubber Masterbatch And Method Of Producing The Same - The present invention provides a natural rubber masterbatch effective in achieving a tread rubber composition which is suitable for heavy-duty tires for rough roads and which is effective in greatly enhancing the abrasion resistance of the tires without impairing the low heat build-up of the tires, a method of producing the natural rubber masterbatch, a rubber composition prepared using the natural rubber masterbatch, and a tire. In a mixing step of mixing a natural rubber latex with a slurry containing water and a carbon black dispersed therein, 10 to 100 weight parts of the carbon black is mixed with 100 weight parts of a natural rubber component in the natural rubber latex. The carbon black satisfies the following conditions: (1) N | 2008-09-04 |
| 20080214701 | Fibers and a Pet Liquid Container - Use of thermoplastic molding compositions comprising
| 2008-09-04 |
| 20080214702 | Biodegradable Aliphatic-Aromatic Polyesters - Biodegradable aliphatic/aromatic copolyester comprising 50 to 60 mol % of an aromatic dicarboxylic acid and 40 to 50 mol % of an aliphatic acid, at least 90% of which is a long-chain dicarboxylic acid (LCDA) of natural origin selected from azelaic acid, sebacic acid, brassylic acid or mixtures thereof; and a diol component. | 2008-09-04 |
| 20080214703 | Pellet and fiber length for polyester fiber reinforced polypropylene composites - The present disclosure is directed generally to polyester fiber reinforced polypropylene resin pellets and methods for producing therein. The polyester fiber reinforced polypropylene resin pellets include at least 25 wt % polypropylene based polymer; from 10 to 40 wt % polyester fiber; from 0 to 60 wt % inorganic filler; and from 0 to 0.2 wt % lubricant. The polyester fiber is incorporated into the resin pellets by feeding chopped fiber or continuous fiber unwound from one or more spools. Articles molded from the polyester fiber reinforced polypropylene resin pellets exhibit a drop dart impact resistance that is dependent on the pellet length and whether the PET fiber is incorporated as chopped fiber or continuous fiber during the extrusion compounding process. Articles molded from the polyester fiber reinforced polypropylene resin pellets find application as automotive parts, household appliance parts, or boat hulls. | 2008-09-04 |
| 20080214704 | Polyproylene of Improved Processability for Production of Pipes - The present invention relates to a polymer composition, comprising (i) a polypropylene-based matrix which comprises a polypropylene random copolymer prepared by copolymerization of propylene with an olefin comonomer, wherein the amount of olefin comonomer units is within the range of (0.2) wt % to (5) wt %, based on the weight of the polypropylene-based matrix, and (ii) an elastomeric copolymer of propylene and at least one olefin comonomer, the polymer composition having a storage modulus G1 at a loss modulus G″=5 kPa of G′(5 kPa)<(3100) Pa, measured at (220° C.). | 2008-09-04 |
| 20080214705 | Pigment Dispersions with Polymeric Dispersants Having Pending Chromophore Groups - A pigment dispersion includes a color pigment and a polymeric dispersant having at least one pending chromophore group covalently bound to the polymeric backbone of the polymeric dispersant through a linking group | 2008-09-04 |
| 20080214706 | Moulded Object Exhibiting a Polychromatic Effect, Associated Light Device and Resin - The present invention relates to a moulded object made of a transparent and coloured plastic exhibiting a polychromatic effect, characterized in that the transparent plastic comprises from 0.1 to 1500 ppm of at least one fluorescent dye and from 50 to 10 000 ppm of at least one optical brightener. It also relates to the resin used for forming the moulded object. It also relates to a light device combining the said moulded object with at least one artificial light source which exhibits an emission in the region of excitation of the optical brightener, in particular in the 300-450 nm range, preferably 350-420 nm range, more preferably still 350-400 nm range. | 2008-09-04 |
| 20080214707 | Nanocomposite Comprising Stabilization Functionalized Thermoplastic Polyolefins - This invention relates to nanocomposites comprising organo-clay and at least one stabilization functionalized thermoplastic polyolefin. Preferably the stabilization functionalized thermoplastic polyolefin is represented by the formula: | 2008-09-04 |
| 20080214708 | Asymmetrically substituted phosphinic acids - The invention relates to asymmetrically substituted phosphinic acids of the formula (I) | 2008-09-04 |
| 20080214709 | Polyurethane Dispersion Containing Alkanolamines - A polyurethane dispersion whose polyurethane comprises anionic groups at least 10 mol % of which are neutralized by alkanolamines having at least two hydroxyl groups, excluding polyurethane dispersions comprising water-emulsifiable polyisocyanates. | 2008-09-04 |
| 20080214710 | Aqueous dispersions - The invention concerns hydrous compositions based on polychloroprene and hydroxylamine derivatives, processes for their production and their use as adhesives. The polychloroprene dispersions are stabilized by the addition of hydroxyalkylamine after removal of residual monomer. | 2008-09-04 |
| 20080214711 | HARD COATS WITH A CATIONIC ACRYLIC POLYMER - A hard coat composition comprising a cationic acrylic polymer is disclosed. The hard coat is suitable for application to a substrate, and can be used without an adhesive promoting primer. | 2008-09-04 |
| 20080214712 | Adjustble Block Copolymer Having Acid Functional Groups and Adhesive and Thermoplastic Compositon Containing It - The invention relates to a linear ethylenic block copolymer comprising:
| 2008-09-04 |
| 20080214713 | Antistatic Method For Biodegradable Polyester Resin Composition And Products Thereof - The present invention relates to antistatic method for a polyester polymer or resin which is a biodegradable resin, especially polybutylene succinate, etc., having a high antistatic ability and persistence thereof, suppressing bleeding with a slight environmental load and to provide a film, a sheet and a molded product, moreover, to provide the antistatic method for the biodegradable polyester resin composition comprising a diglycerol fatty acid ester in a polyester resin having biodegradability, said polyester resin composition is at least one of polybutylene succinate, polyethylene succinate, polybutylene adipate, or polybutylene succinate adipate, constituent fatty acids of said diglycerol fatty acid ester have 16-18 Carbon atoms, and HLB of the diglycerol fatty acid ester is within the range of 4-8, moreover, the content of the diglycerol fatty acid is =0.2 to <2.0 wt. %. | 2008-09-04 |
| 20080214714 | POLYTETRAFLUOROETHYLENE AQUEOUS DISPERSION AND ITS PRODUCT - To provide a polytetrafluoroethylene (PTFE) aqueous dispersion, which does not substantially contain ammonium perfluorooctanoate and is excellent in mechanical stability, wettability, permeability and coating property, and its product. | 2008-09-04 |
| 20080214715 | Flame Retardant Polymeric Compositions - The present invention provides flame retardant thermoplastic moulding compositions comprising:
| 2008-09-04 |
| 20080214716 | Use of a Thermally Curable Aqueous Composition as a Binder for Substrates - The present invention relates to the use of a heat-curable aqueous composition comprising dispersed polymer particles of at least
| 2008-09-04 |
| 20080214717 | Resin Composition - The present invention has its object to provide a resin composition excellent in gas barrier properties, mechanical strength and elasticity and further showing only a slight extent of gravity deformation under high temperature conditions. The invention relates to a resin composition which comprises an isobutylene-based polymer (A), an isobutylene-based block copolymer (B) comprising a polymer block (b1) the constituent monomer(s) of which is(are) an aromatic vinyl compound(s) and a polymer block (b2) the constituent monomer(s) of which is(are) isobutylene, and a filler (C). This composition can be used as a sealant, in particular as a hot melt sealant for double glazing units, and as a hot melt spacer material for double glazing units. | 2008-09-04 |
| 20080214718 | HYDROPHOBIC METAL AND METAL OXIDE PARTICLES WITH UNIQUE OPTICAL PROPERTIES - Treating metal or metal oxides such as ZnO with PIBSA and analogous molecules yields a hydrophobic powder. The powder can provide improved optical clarity when incorporated into a polymer matrix in comparison to untreated hydrophilic ZnO. | 2008-09-04 |
| 20080214719 | Aqueous Formulations Containing Polyaromatic Compounds With Acid Groups - The present invention relates to a process for preparing aqueous formulations (A) comprising at least one polyaromatic compound bearing acid groups, in particular a sulfonated polyaromatic compound, and also aqueous formulations (A) which have been prepared by the process of the invention. Furthermore, the present invention relates to a process for preparing dried formulations (B) by removing the water from the aqueous formulations (A) and also the dried formulations (B) themselves. The present invention further provides a formulation (C) comprising the dried formulation (B) of the invention and water or the formulation A of the invention and a water-comprising formulation (D) comprising the aqueous formulation (A) or the formulation (C) of the invention and additionally at least 2% by weight of an organic solvent. Furthermore, the present invention relates to dry formulations (E) which are obtained by removing water and solvent from the water-comprising formulations (D) of the invention. The present invention further provides for the use of the water-comprising formulations (D) of the invention and of the dry formulations (E) obtained from these for producing a polymer electrolyte membrane and also the polymer electrolyte membrane itself and a membrane-electrode assembly (MEA) and also a fuel cell comprising the polymer electrolyte membrane of the invention. | 2008-09-04 |
| 20080214720 | Thermoplastic molding composition based on AES rubber with low surface gloss - A thermoplastic composition suitable for making articles having low gloss and good impact properties is disclosed. The composition contains
| 2008-09-04 |
| 20080214721 | POLYESTER-POLACRYLATE DISPERSIONS FOR TWO-COMPONENT COATING COMPOSITIONS - The invention relates to aqueous polyester-polyacrylate dispersions based on copolymers, to a process for their preparation, and to aqueous coating compositions based thereon and the use thereof as lacquers. The dispersions are prepared from a polyester component A) that comprises the reaction product of A1) one or more saturated, aliphatic and/or aromatic di-, tri- or tetra-carboxylic acids or their anhydrides, and A2)one ore more diols and/or polyols, and a polyacrylate component B) that comprises the reaction product of B1) one or more OH-group-free (meth)acrylic acid esters and/or vinyl aromatic compounds, B2) one or more hydroxy-functional vinyl monomers or hydroxy-functional (meth)acrylic acid esters, and B3) one or more acid-group-containing monomers capable of free-radical copolymerisation, herein te polyester component A) has a hydroxyl number of from 180 to 300 mg KOH/g substance and an acid number of from 0.5 to 30 mg KOH/g, and the polyacrylate component B) has a hydroxyl number of from 10 to 180 mg KOH/g and an acid number of from 10 to 100 mg KOH/g, and the copolymer has an OH number smaller than that of the polyester component A) and greater than 27 mg KOH/g. | 2008-09-04 |
