| 36th week of 2015 patent applcation highlights part 5 |
| Patent application number | Title | Published |
|---|
| 20150245955 | CONTAINER FOR SURGICAL ABSORBENT ARTICLES - A surgical container has more than one surgical sponge, more than one dispensing containers containing respectively the more than one surgical sponge, and more than one disposal containers each proximate to and visually associated respectively with the more than one dispensing containers to receive a used surgical sponge, wherein a selected surgical sponge is visible in one of the dispensing container or the corresponding disposal container. | 2015-09-03 |
| 20150245956 | ABSORBENT ARTICLE - An absorbent article includes a liquid-permeable top sheet, a liquid-impermeable back sheet, and an absorbent body between the top and back sheets. The top sheet has first and second areas, each of which includes a blood lubricity-imparting agent that has a kinematic viscosity of 0.01-80 mm2/s at 40 C, a water hold percentage of 0.01-4.0 mass %, and a weight average molecular weight of less than 1,000. The first area overlaps at least partially with an excretory orifice contact area of the top sheet that is configured to contact with the excretory orifice of the wearer. The second area is arranged more to a rear side in a lengthwise direction of the absorbent article than is the first area. A basis weight of the blood lubricity-imparting agent in the first area is higher than that of the blood lubricity-imparting agent in the second area. | 2015-09-03 |
| 20150245957 | ABSORBENT ARTICLE - In an absorbent article, in which each of pressure-bonded parts has a linear shape extending in the length direction of the absorbent article, the pressure-bonded parts are formed with spacing at regular intervals in a discontinuous manner with respect to the length direction of the absorbent article and are also formed in multiple lines with spacing at regular intervals with respect to the width direction of the absorbent article, depressed parts are formed on a back-sheet-facing surface of an absorbent body that is located beneath the pressure-bonded parts, each of an excretory opening-contacting region in a top sheet and the pressure-bonded parts contains a blood lubricity-imparting agent having a kinematic viscosity of 0.01 to 80 mm | 2015-09-03 |
| 20150245958 | ABSORBENT ARTICLE WITH MULTI-LAYER FOLDED ABSORBENT CORE - Absorbent laminates and multi-layer, folded absorbent cores comprising the absorbent laminates for use in absorbent articles are presented. Specifically, multi-layer, folded absorbent cores are presented that are formed from an absorbent laminate comprising an absorbent layer between two tissue layers, in which the absorbent core includes a central channel running longitudinally along the core and crenellations profiled along the thickness of the core and providing enhanced liquid distribution across the core surface area or profile and improved liquid absorption into the laminate. | 2015-09-03 |
| 20150245959 | FASTENER FOR AN ABSORBENT ARTICLE - An absorbent article includes front and rear portions and a fastener for connecting side edges of the front and rear portions. The fastener includes a grasping element attached to an outer surface of the fastener to provide for grasping by the wearer or caregiver. The grasping element may be formed of flexible material and may have a variety of configurations, including a tube, a flange, a tunnel or a pocket. | 2015-09-03 |
| 20150245960 | DISPOSABLE ARTICLE COMPRISING NON HOOK COMPATIBLE AREAS - The invention relates to a disposable article having a longitudinal direction, a longitudinal centre line and a transverse direction, wherein the article has a first and a second longitudinal edge, a first and a second transverse edge, wherein the article comprises a first covering layer comprising a first surface intended to face towards the user and a second surface intended to face away from the user in use, wherein at least a first and a second fixing member comprising hook elements are arranged on the first surface close to the first transverse edge, wherein the first fixing member is arranged close to the first longitudinal edge and the second fixing member is arranged close to the second longitudinal edge, wherein substantial parts of the first surface are compatible with the hook elements. | 2015-09-03 |
| 20150245961 | METHOD FOR PRODUCING OR CALIBRATING A CONTROL PROFILE FOR A WHEELCHAIR - A method and system for calibrating a control profile of a controller having at least one output variable used to control the operation of a mobility device. The calibration system controls the mobility device according to a prescribed routine under a range of changes of values of the output variable. One or more sensors provided, either temporarily or permanently, on the mobility device sense operational parameters of the mobility device and send sensed data to the calibration system. The calibration system determines mobility device stability associated with the changes of the at least one output variable based on the sensed data and produces a control profile that restricts a controller from outputting changes of values of the output variable associated with mobility device instability. | 2015-09-03 |
| 20150245962 | PASSENGER CARRYING MOBILE ROBOT - A single passenger carrying mobile robot, includes a single operated member that is operated by a passenger to instruct both a moving direction and a moving speed of the passenger carrying mobile robot, a moving member configured to move the passenger carrying mobile robot and a controller configured to control the moving member based on input information input to the operated member by the passenger, wherein the passenger carrying mobile robot further includes a sensor that acquires obstacle information of a surrounding of the passenger carrying mobile robot, and the controller predicts an expected course of the passenger carrying mobile robot based on the input information and determines based on the obstacle information whether or not an obstacle is located in the expected course, and changes a control of the moving member when determining that the obstacle is located. | 2015-09-03 |
| 20150245963 | FOLDABLE WHEELCHAIR FRAME INCLUDING A SELF LOCKING DEVICE - The present invention relates to a foldable wheelchair frame ( | 2015-09-03 |
| 20150245964 | WHEELCHAIR BACKREST HAVING POSITION ADJUSTMENT - An adjustable backrest support provides a seat back angle adjustment that eases the task of adjusting the position of a wheelchair backrest while keeping the user seated in their wheelchair. In one embodiment, the adjustable backrest support includes a strut, an adjuster ring, an adjusting barrel nut, an angle adjuster, and a clamping system including a clamp. The clamp may include clamping screws that permit adjustment of the seat back reclining angle the angle or the seat back lateral position when loosened. | 2015-09-03 |
| 20150245965 | Operating Unit for a Medical Apparatus - This disclosure provides operating units for a medical apparatus having a driven movable element comprising a fixing device for being fixed to the movable element, an actuating element, a signal processing device, at least one actuation sensor for detecting an actuation of the actuating element in at least one predetermined actuation axis (B | 2015-09-03 |
| 20150245966 | Support Surface System for Securing Objects - An apparatus has conforming arms each respectively attached to a support surface in a pattern for cooperatively receiving an object. Actuators respectively position the plurality of conforming arms between a disengaged state to receive the object and an engaged state to contact the object at a respective contact area to immobilize the object. A control system selectively controls each of the actuators to cause the respective one of the conforming arms to curve inwardly toward the object to cooperatively exert a grasping force upon the object such that only a fraction of total force required to immobilize the object is applied to the object by each individual conforming arm. A selected grasping force of a selected one of the conforming arms corresponds to a relative fragility of the respective contact area. | 2015-09-03 |
| 20150245967 | HEAD RELAXING PILLOW - The present invention is to provide a head relaxing pillow, which is made of an elastic material and includes a supporting main body having a top for supporting the neck of a user who lies face up and a bottom concavely provided with a recess, two contact portions each having one end connected to one of the two corresponding ends of the supporting main body and the other end corresponding in configuration to one of the user's parietal bones, and a pressing portion extending from one side of the supporting main body and located between the contact portions. The supporting main body is provided with two sunken portions which are adjacent to two corresponding ends thereof respectively. Thus, when the user's neck and head are resting on the supporting main body and the contact portions respectively, the two sunken portions are corresponding in position to the user's temporal bones respectively. | 2015-09-03 |
| 20150245968 | Facial Cradle - A cradle for facial support of a prone patient's head, the patient's head having a glabellar acupressure point between his or her eyes, the cradle including an “E” cushion having upper and lower ends, and having left, right, and medial arms, each arm among the left, right, and medial arms having proximal and distal ends; the “E” cushion's medial arm being adapted for, upon the facial support of the patient's head, impinging against his or her glabellar acupressure point; the cradle further incorporating a rigid base fixedly attached to the “E” cushion's lower end and “velcro” pads for releasably mounting the “E” cushion upon the support bracket arms of an examination table. | 2015-09-03 |
| 20150245969 | DUAL COLUMN SURGICAL TABLE HAVING A SINGLE-HANDLE UNLOCK FOR TABLE ROTATION - A surgical patient support includes a foundation frame, a support top, and a brake system. The foundation frame includes a first column and a second column. The support top is coupled to the first column and the second column for rotation about a top axis extending along the length of the support top. A single-handle unlock for the support top is also provided. | 2015-09-03 |
| 20150245970 | Method of Securing a Patient onto an Operating Table when the Patient is in the Trendelenburg Position and Apparatus Therefor Including a Kit - A method of securing a patient onto an operating table when the patient is in the Trendelenburg position and apparatus therefor including a kit. A viscoelastic pad is used to support and hold a patient on a medical procedure table during a medical procedure performed while the table, and thus the patient lying thereon, is in an inclined position, such as the Trendelenburg position. The viscoelastic pad has characteristics which promote a minimization of pressure forces on the patient's body, as well as promote a secure cushioning and holding of the patient in a desired position on the table, in order to minimize injury to the patient. | 2015-09-03 |
| 20150245971 | ADAPTER PLANE FOR SURGICAL TABLE, IN PARTICULAR FOR HIP REPLACEMENT SURGERY WITH ANTERIOR APPROACH - Adapter plane ( | 2015-09-03 |
| 20150245972 | FINGER JOINT DRIVING DEVICE - A finger joint driving device is provided on a hand and causes a finger joint to be turned. The finger joint driving device includes a first base portion that is mounted on the hand, a first link portion that is turnably provided on the first base portion, a second link portion that is turnably provided on the first link portion, a second base portion that is mounted on the end side of a finger from the first base portion in the hand and is provided on the second link portion so as to relatively approach with respect to and to be separated from the first base portion, and a driving unit that drives the second link portion to be turned. | 2015-09-03 |
| 20150245973 | WALKER APPARATUS AND BACKREST THEREFOR - There is provided a walker apparatus having a pair of spaced-apart, upright frame members. The walker apparatus includes a seat operatively connected to the upright frame members. The walker apparatus has a backrest cantilevered from the frame members. The backrest has at least one opening extending therethrough for permitting a user's vision past the backrest when the user grips the upright frame members. | 2015-09-03 |
| 20150245974 | COMPONENT MODULE FOR A REDUCED PRESSURE TREATMENT SYSTEM - A reduced pressure treatment system includes a control unit having a control system and a reduced pressure source. The reduced pressure treatment system further includes a manifold unit in fluid communication with the reduced pressure source and a component module to augment treatment. The component module is configured to communicate with the control system of the control unit, and the component module includes a first mounting region configured to be coupled to a complimentary mounting region of the control unit. The component module further includes a second mounting region identical to the complimentary mounting region of the control unit to allow a second component module to be coupled to the first component module. | 2015-09-03 |
| 20150245975 | Therapeutic Compression Apparatus - A bladder assembly for a compression apparatus for providing pressure to a limb, where the bladder assembly includes at least one bladder. The bladder includes a first and a second flexible wall secured to one another about a peripheral edge thereof to form an air pocket. The bladder further includes at least one spot weld provided in a predetermined location inward of the peripheral edge connecting the first and second walls to one another to define a plurality of chambers within the air pocket. | 2015-09-03 |
| 20150245976 | PRESSURE CUFF OR GARMENT - A pressure cuff or garment for prophylactic treatment of deep vein thrombosis includes a series of three chambers arranged in series and coupled fluidically to one another by bleed tubes or chokes. The chambers are otherwise sealed to the environment, save for the first chamber which also provides an inlet/outlet for coupling to a fluid pump. The chambers are also of curved shape so as to overlap one another. The cuff or garment provides more effective pulsating pressure treatment than prior art structures. | 2015-09-03 |
| 20150245977 | REHABILITATION DEVICE - A rehabilitation device is provided. The rehabilitation device may include a plurality of modular canes, a plurality of rollers, at least one divider, a first end cap and a second end cap. Each tubular modular cane may terminate in the first end and an opposing second end. The second end diameter may be sized to slidably receive the first end. The second end cap may have a second connection end sized to slidably receive the first end. The first end cap may have first connection end adapted to slidably receive the second end. The plurality of rollers may be made of compressible material. The plurality of rollers may be mounted on the plurality of modular canes so that the rehabilitation device may have an adjustable length with interchangeable rollers. The plurality of rollers may be separated by at least one divider so as to adjust the spacing of the plurality of rollers. | 2015-09-03 |
| 20150245978 | SYSTEMS AND METHODS FOR HAPTIC STIMULATION - A system for sexual stimulation includes a first sexual stimulation device having a first sensor and a first actuator and a second sexual stimulation device having a second sensor and a second actuator. The first sexual stimulation device is configured to communicate information from the first sensor to actuate the second actuator of the second sexual stimulation device and the second sexual stimulation device is configured to communicate information from the second sensor to actuate the first actuator of the first sexual stimulation device. | 2015-09-03 |
| 20150245979 | Control Arrangement for Controlling the Intensity of the Massaging Motion of a Massage Device and a Massage Device Comprising a Control Arrangement of this Type - The invention relates to a method for controlling the intensity of the massaging motion of a massage device including at least one preferably elongated massage section with at least one wall that forms the outer surface of the massage section. The massage device also has at least one first electric drive device having a first electric motor unit and at least one second drive device having a second electric motor unit, at least some sections of each unit being operatively connected either directly or indirectly to the wall in order to generate a massaging motion. A control assembly, which is connected to the electric motor units, is provided to control the intensity of the massaging motion. The current electric power consumption of at least the first electric motor unit is particularly advantageously determined periodically or continuously, the electric power consumption that has been determined is compared to at least one predefined reference power consumption and the intensity of the massaging motion generated by the second electric motor unit is controlled depending on the result of said comparison. | 2015-09-03 |
| 20150245980 | CHILD RESISTANT PACKAGING - A child resistant blister pack includes a blister layer which includes one or more blister cavities for receiving a product. A frangible retaining layer is attached to the blister layer over the blister cavities to retain the product within the blister cavities. A first backing layer is attached to the retaining layer on a side opposite the blister layer. The first backing layer has one or more lines of weakness aligned with the blister cavities. A second backing layer is attached to the first backing layer on a side opposite the retaining layer. The second backing layer has a plurality of removable sections. At least two removable sections are arranged over each line of weakness in the underlying first backing layer. | 2015-09-03 |
| 20150245981 | Teething Bracelet - A bracelet to be worn by an adult caretaker of an infant or baby is disclosed. A washable terry cloth bracelet fastens around the wearer's wrist with hook and loop fabric or other suitable fastener. A plurality of loops is sewn to the bracelet around its lower circumference and retains a set of teething rings. The rings may be removable or non-removable. In addition, a plurality of smaller loops is also sewn to the lower circumference of the bracelet. These loops may be used to attach additional toys, charms and other articles that wearer may like to provide for the baby or display. The bracelet, large and small loops, and teething rings may be provided in a wide variety of colors, shapes, patterns, styles, and designs. | 2015-09-03 |
| 20150245982 | NAIL POLISH DRYING METHOD AND PRODUCT THEREFOR - The invention comprises a nail drying aerosol spray that comprises a combination of solvents having different rates of volatility. One of the solvents is dimethyl ether. | 2015-09-03 |
| 20150245983 | FLUORIDE RELEASING DENTAL COMPOSITION AND DENTAL APPLIANCE - A fluoride-releasing dental composition includes a polymeric compound selected from (meth)acrylate polymers, (meth)acrylate copolymers, ethylene vinyl acetate copolymers, and mixtures and combinations thereof; and a cariostatically effective amount of a fluoride compound. A dental appliance made from the fluoride-releasing dental composition. | 2015-09-03 |
| 20150245984 | METHOD OF SIMULTANEOUSLY CLEANING AND WHITENING TEETH - Compositions and methods for whitening the teeth of a patient or subject include the application of at least one tooth whitening composition having a viscosity of at least 100 centipoise to the surface of a stained tooth, accompanied by the application of a sealant composition that forms protective film or coating on the tooth surface to resist moisture contamination of the oxidizing composition. The whitening procedure can be further enhanced by removal of acquired pellicle from the tooth surface prior to application of oxidizing and sealant compositions. The novel procedure allows for a high degree of tooth whitening by protecting the oxidizing composition while it is in contact with the tooth surface. | 2015-09-03 |
| 20150245985 | FLAVOR AND FRAGRANCE FORMULATION (II) - The present invention relates to the use of specific organic compounds as flavor and fragrance material. Furthermore the invention relates to a new specific organic compound, as well as to flavor and fragrance formulations comprising at least one of the specific organic compounds. | 2015-09-03 |
| 20150245986 | Foam improvement of soap containing compositions - The present invention concerns the use of a combination of an amphoteric surfactant and a cationic polymer derivative of polysaccharide to increase the foam volume and foam quality of soap containing compositions. Said advantage may be used to produce cleansing products like cleansing liquid, paste, gel or foam, body shampoo or hair shampoo. | 2015-09-03 |
| 20150245987 | COMPOSITION AND PROCESS FOR PERMANENT SHAPING OF HUMAN HAIR - Present invention relates to a composition and a process for the permanent shaping of human hair used both for the permanent waving of human hair with an excellent waving effect as well as for the straightening of either naturally or chemically curled hair wherein optimum hair conditioning is observed. The present invention is an aqueous composition for permanent shaping and/or straightening hair based on at least one reducing agent and comprising further aqueous dispersed droplets of ethylene/octene copolymer stabilized with ethylene/sodium acrylate copolymer. Present invention is at the same time on the process for permanent shaping wherein the composition of the invention is used. | 2015-09-03 |
| 20150245988 | LIQUID COSMETIC AND/OR DERMOCOSMETIC COMPOSITION - A cosmetic and/or dermocosmetic composition for its application in the treatment of skin, scalp and/or hair is disclosed. The composition is characterized for being a liquid compound that is dosed using a spray/aerosol system and for being composed by an active ingredient consisting on clay and cocoa powder, a skin beneficial compound if desired and water and wine alone or combined as disperse phase. The composition is isolated in a chamber without any contact with the propellant, suffers a distinctive maturation process and is rheologically designed for being able to fill and dose from the packing. | 2015-09-03 |
| 20150245989 | SKIN CARE METHOD AND KIT - A skin care method and kit is disclosed that includes instructions for a dietary skin care regimen. The regimen includes a list of prohibited and allowed foods. The list of prohibited foods includes red meat, chocolate, eggs, confections, alcoholic beverages, shellfish, fried foods, and tomatoes. The list of allowed foods includes chicken, turkey, non-fried fish, vegetables, fruit other than a tomato, and olive oil as a salad dressing. The skin care kit further includes a compliance report including the list of prohibited and allowed foods with corresponding data input fields for each food in the list of prohibited and allowed foods. The user indicates an amount of each prohibited and allowed food item consumed by the user in the corresponding data input field. A compliance rating system is disclosed in which the total number of servings of prohibited and allowed foods consumed by the user determines the user's compliance level. | 2015-09-03 |
| 20150245990 | OLIVE SEED JUICE AND A METHOD TO PREPARE IT - The invention relates to cosmetics sector. The invention particularly relates to cell regenerative juice obtained from olive seed ash to be used in place of aqua (mineral) and distilled water in the cosmetics sector and to the method of obtaining this juice. | 2015-09-03 |
| 20150245991 | Anti-aging dermal composition comprising herbal extracts - This application discloses an anti-aging composition for dermal application comprising cannabidiol hemp oil, chuanxiong extract, mondo grass extract, Chinese foxglove extract, female and | 2015-09-03 |
| 20150245992 | PHARMACEUTIC OSMOTIC PUMP PREPARATION - Provided in the present invention is a pharmaceutic osmotic pump preparation comprising a tablet core, wherein the tablet core contains drugs (or pharmaceutically active ingredients) and materials forming a chamber structure; and a coating film coating the tablet core where a drug release hole is set; wherein when the pharmaceutic osmotic pump preparation releases drugs in water or an aqueous medium, the materials forming the chamber structure lead to the formation of a superfine chamber structure in the coating film, and the total volume of the superfine chamber structure Vb gradually increases over the releasing time, but the releasing rate R (or release amount A) of the pharmaceutically active ingredients is proportional to Vb. The osmotic pump preparation of the present invention is suitable for water-soluble drugs and water-insoluble drugs, and especially is suitable for the controlled release of low solubility drugs or pH dependent drugs. | 2015-09-03 |
| 20150245993 | MATRIX CARRIER COMPOSITIONS, METHODS AND USES - Provided is a matrix carrier composition for use in pharmaceutical delivery system, the composition comprising an intermolecular association of at least a first solid phase comprising nanoparticles having hydrophobic surface, wherein the size of the nanoparticles is in the range of about 5-1000 nm, a second solid phase, comprising a biopolymer having hydrophilic and hydrophobic parts, and a continuous phase comprising oil associated with the first and said second solid phases. | 2015-09-03 |
| 20150245994 | THERAPEUTIC OR PREVENTIVE AGENT FOR MEIBOMIAN GLAND DYSFUNCTION OR MEIBOMIAN GLAND BLOCKAGE - The objective of the present invention is to provide a new medicinal use of clarithromycin. The present invention is a therapeutic agent or a preventive agent for meibomian gland dysfunction or meibomian gland blockage and comprises clarithromycin as an active ingredient. The dosage form is preferably an eye drop or eye ointment. | 2015-09-03 |
| 20150245995 | Stable Quick Dissolving Dosage Form Comprising Amoxicillin and Clavulanic Acid - A quick dissolving pharmaceutical formulation is disclosed. In one embodiment, the formulation includes at least the following components: (1) from about 35 to about 50 weight percent amoxicillin or a pharmaceutically acceptable salt thereof; (2) from about 2.0 to about 12 weight percent clavulanic acid or a pharmaceutically acceptable salt thereof; (3) from about 30 to about 40 weight percent mannitol; (4) from about 2 to about 7 weight percent crospovidone; (5) from about 0.5 to about 2.0 weight percent colloidal silicon dioxide; and (6) from about 2.0 to about 5.0 weight percent sodium stearyl fumarate. A method for making a quick dissolving pharmaceutical tablet is also disclosed. | 2015-09-03 |
| 20150245996 | REMELTED INGESTIBLE PRODUCTS - A method of preparing an orally ingestible hard boiled product, comprising: i) heating a sugar material to a first temperature sufficient to liquefy the sugar material; ii) cooling the liquefied sugar material to provide a cooled sugar material having a solid or semi-solid form; iii) heating the cooled sugar material to a second temperature, which is lower than the first temperature; iv) combining the sugar material with one or more temperature sensitive ingredients before, during, or after said heating step iii), but after said cooling step ii), such that an intimate mixture of the second liquefied sugar material and the one or more temperature sensitive ingredients is provided; and v) cooling the intimate mixture to form an orally ingestible product. Orally ingestible hard boiled products prepared according to this method are also provided. | 2015-09-03 |
| 20150245997 | LIPID MEMBRANE STRUCTURE INCLUDING BACTERIAL CELL COMPONENT HAVING DISPERSIBILITY IN NON-POLAR SOLVENT, AND METHOD FOR PRODUCING SAME - [Problem] To provide: a lipid membrane structure which has such a particle diameter that the lipid membrane structure can be sterilized by filtration, contains a lipid that is bound to a peptide composed of multiple arginine residues as a constituent lipid, and includes a bacterial cell component having dispersibility in a non-polar solvent; and a method for producing a lipid membrane structure which has such a particle diameter that the lipid membrane structure can be sterilized by filtration and includes a substance of interest having dispersibility in a non-polar solvent. | 2015-09-03 |
| 20150245998 | Doxycycline Formulations, and Methods of Treating Rosacea - The present invention is directed to a pharmaceutical composition in unit dose form for orally delivering doxycycline to a human, the pharmaceutical composition comprising: a capsule, wherein the capsule is coated with a delayed release layer; wherein the delayed release layer comprises about 4 to 6 mg of doxycycline monohydrate and a binding agent, and wherein the delayed release layer is coated with an enteric coating; wherein the enteric coating dissolves at pH of about 5 to 6, and wherein the enteric coating is coated with an immediate release layer; wherein the immediate release layer comprises about 32 mg of doxycycline monohydrate and a binding agent, wherein the relative mean C | 2015-09-03 |
| 20150245999 | PHARMACEUTICAL COMPOSITION - The invention provides a pharmaceutical composition comprising activated carbon particles, for oral administration. The pharmaceutical composition may be for (use in) the treatment of gastrointestinal fistula. | 2015-09-03 |
| 20150246000 | DRUG DELIVERY SYSTEM AND METHOD FOR THE TREATMENT OF NEURO-DEGENERATIVE DISEASE - Embodiments of the present invention are directed to the oral administration of Bryostatins for the treatment of neuro-degenerative disease. | 2015-09-03 |
| 20150246001 | PROCESS FOR THE MANUFACTURING OF A MULTILAYER DRUG DELIVERY CONSTRUCT - The present invention relates to a process for the manufacturing of a multilayer construct comprising layering at least one drug loaded film from which each film comprises a polymer and at least a drug manufactured by the steps of dissolving the polymer in an organic solvent, mixing the dissolved polymer with the drug, laminating the mixture between at least two polymeric sheets, whereby at least one sheet is permeable to the organic solvent, removing the sheets to provide the drug loaded film, layering the drug loaded film and fusing the drug loaded films into a multilayer construct. The present invention also relates to the multilayer construct obtainable by the process according to the present invention and to the use of the multilayer construct in ophthalmology, cardiovascular, pain management, musculoskeletal, cancer treatment or in vaccine delivery. | 2015-09-03 |
| 20150246002 | ABUSE-RESISTANT MUCOADHESIVE DEVICES FOR DELIVERY OF BUPRENORPHINE - The present invention provides abuse deterrent mucoadhesive devices for delivery of buprenorphine. Each device comprises a mucoadhesive layer and a backing layer, and the pH in each layer is selected, such that absorption of buprenorphine is maximized. | 2015-09-03 |
| 20150246003 | MULTIDIRECTIONAL MUCOSAL DELIVERY DEVICES AND METHODS OF USE - The present invention relates to a pharmaceutical dosage form for transmucosal delivery of an active agent to two or more mucosal surfaces. The dosage form is presented as a transmucosal delivery device. The devices of the invention may include at least two mucoadhesive surfaces. The devices may further include an intermediate layer disposed between the mucoadhesive layers. The pharmaceutical can be incorporated in any one or all of the mucoadhesive layers or the intermediate layer. Upon application, the device adheres to at least two surfaces, providing transmucosal delivery of the drug to at least two surfaces. | 2015-09-03 |
| 20150246004 | TRANSDERMAL DELIVERY DEVICE AND METHOD - A transdermal delivery device is provided for delivering at least one active therapeutic compound to rapidly induce a therapeutic effect, the device comprising: a pad for receiving a depot of the at least one therapeutic compound, the pad having a portion of material of high compression resistance; and the device also comprising a backing layer of greater cross-section than the pad. A method for rapidly reducing a therapeutic effect and a transdermal delivery but for delivering at least one therapeutic compound to rapidly induce a therapeutic effect are also provided. | 2015-09-03 |
| 20150246006 | TRANSDERMAL SYSTEMS HAVING CONTROL DELIVERY SYSTEM - Transdermal delivery systems are disclosed including a backing layer, a polymer membrane within the backing layer, an adhesive layer for attaching the delivery system to the patient's skin or mucosa, and a releasable layer covering the adhesive layer prior to use, the polymer membrane impregnated with sufficient fluid medium to alter the rate of transmission of an active agent through the polymer membrane, with the amount of fluid medium being greater than the amount retained by the fluid membrane upon drying. | 2015-09-03 |
| 20150246007 | TRANSDERMAL NICOTINE SALT DELIVERY SYSTEM - A transdermal nicotine salt delivery system to an individual. The system has a high nicotine salt loading to effect therapeutic flux rate. Acrylate polymeric drug reservoir with the high nicotine salt dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties. | 2015-09-03 |
| 20150246008 | USES OF COMPOSITIONS CONTAINING A ROASTED EXTRACT AND XANTHOHUMOL - The present invention primarily relates to specific uses of a composition containing a roasted extract and xanthohumol for health-promoting purposes. In particular, the invention relates to a composition, preferably pharmaceutical composition, comprising xanthohumol (XN), preferably in a therapeutically effective amount, for (i) use in the treatment and/or prevention of cancer, and/or (ii) use in the treatment and/or prevention of osteoporosis, and/or (iii) use in the treatment and/or prevention of metabolic syndrome, and/or (iv) use in the treatment and/or prevention of diabetes, and/or (v) use in the treatment and/or prevention of cardiovascular disease(s), and/or (vi) use as anti-oxidant, and/or (vii) use as detoxifying agent, and/or (viii) inhibiting metabolic activation of procarcinogens, and/or (ix) use as anti-mutagenic and/or anti-genotoxic agent, and/or (x) use as anti-estrogenic and/or estrogenic agent, and/or (xi) inducing apoptosis, and/or (xii) use as anti-angiogenetic agent, and/or (xiii) use as anti-inflammatory agent, and/or (xiv) inhibiting NF-κB, and/or (xv) use in the treatment and/or prevention of infection(s), in particular, use as antimicrobial agent, wherein the composition comprises or consists of (a) a roasted extract and (b) XN, preferably a hop extract comprising XN, and/or wherein the composition is obtainable or obtained by mixing (a) a roasted extract and (b) XN or, preferably, a hop extract comprising XN. | 2015-09-03 |
| 20150246009 | Stable injectable pharmaceutical composition of epinephrine or salts thereof - The present invention refers to a stabilized injectable pharmaceutical composition of epinephrine or salts thereof comprising sodium metabisulfite, wherein the ratio of the amount of epinephrine or salt thereof to sodium metabisulfite in the composition ranges from about 1:0.005 to about 1:1.5 by weight. It has been observed that stable injectable epinephrine compositions with excellent storage stability and substantially free of overages can be prepared using sodium metabisulfite in said ratios. Particularly, it was found that using sodium metabisulfite in said ratios controls levels of adrenaline sulfonate impurity in said pharmaceutical compositions. | 2015-09-03 |
| 20150246010 | HISTONE ACETYL TRANSFERASE ACTIVATORS AND HISTONE DEACETYLASE INHIBITORS IN THE TREATMENT OF ALCOHOLISM - The present invention relates to the reduction of a symptom of an alcohol withdrawal state comprising administering a modulator of histone acetylation. | 2015-09-03 |
| 20150246011 | NUTRITIONAL COMPOSITIONS INCLUDING CALCIUM BETA-HYDROXY-BETA-METHYLBUTYRATE, PROTEIN AND LOW LEVELS OF ELECTROLYTES - Disclosed are nutritional compositions, and methods of using and making the nutritional compositions, that include calcium beta-hydroxy-beta-methylbutyrate and protein. The calcium beta-hydroxy-beta-methylbutyrate is in sequestered or ion-exchanged form to reduce the interaction of the calcium with the protein in the nutritional composition and improve the overall stability of the nutritional composition. | 2015-09-03 |
| 20150246012 | OMEGA 3 FATTY ACID FOR USE AS A PRESCRIPTION MEDICAL FOOD AND OMEGA 3 FATTY ACID DIAGNOSTIC ASSAY FOR THE DIETARY MANAGEMENT OF CARDIOVASCULAR PATIENTS WITH CARDIOVASCULAR DISEASE (CVD) WHO ARE DEFICIENT IN BLOOD EPA AND DHA LEVELS - The present invention provides a kit for the dietary management of cardiovascular patients with cardiovascular disease who are deficient in blood Eicosapentaenoic acid (EPA) and Docosahexaenoic acid (DHA) levels, said kit including a diagnostic assay for determining blood levels of EPA, DHA and Docosapentaenoic acid (DPA) and a pharmaceutical grade prescription medical food omega-3 fatty acid formulation containing about 90% or more omega 3 fatty acids by weight including a combination of EPA, DPA and DHA in a weight ratio of EPA:DHA of from 5.7 to 6.3, wherein the sum of the EPA, DHA and DPA are about 82% by weight of the total formulation and about 92% of the total omega 3 fatty acid content of the composition. | 2015-09-03 |
| 20150246013 | OMEGA-3 ENRICHED FISH OIL-IN-WATER PARENTERAL NUTRITION EMULSIONS - An emulsion is provided including: an oil component and a water component, the oil component including: fish oil triglycerides in an amount of about 60% to about 90% based on the weight of the oil component; wherein the fish oil triglycerides include omega-3 fatty acids, expressed as triglycerides, in an amount of at least 60%, based on the total weight of the fatty acids of the fish oil triglycerides; wherein the fish oil triglycerides include a total amount of EPA and DHA, expressed as triglycerides, of at least 45%, based on the total weight of the fatty acids of the fish oil triglycerides; and, at least one medium-chain triglyceride, wherein a total amount of the at least one medium-chain triglyceride is from about 10% to about 40% based on the weight of the oil component. | 2015-09-03 |
| 20150246014 | Derivatives of Propane Diyl Dicinnamate - The present invention provides a method for treating a cancer in a subject involving administering to the subject a compound of formula (II) or (II′): | 2015-09-03 |
| 20150246015 | Esters of Short Chains Fatty Acids for Use in the Treatment of Immunogenic Disorders - The present invention relates to short chain fatty acids (SCFA) for use in transmucosal administration to a subject for the prevention, attenuation or treatment of a disease or disorder associated with a compromised Th1 immune response and/or an unwanted Th2 or Th2-like immune response by modulating a Th2 immune response towards a Th1 immune response, particularly for the treatment, prevention and/or amelioration of viral infections and as an adjuvant for promoting the efficiency of vaccines and/or prevention of allergic diseases or disorders. | 2015-09-03 |
| 20150246016 | CONTROLLED RELEASE ENTERIC SOFT CAPSULES OF FUMARATE ESTERS - Described herein are pharmaceutical compositions comprising fumarate esters, methods for making the same, and methods for treating subjects in need thereof. In particular, oral pharmaceutical compositions comprising controlled release enteric soft capsules and matrices comprising fumarate esters are described. | 2015-09-03 |
| 20150246017 | PHARMACEUTICAL COMPOSITION COMPRISING BENZYL ALCOHOL FOR THE TREATMENT OF MIGRAINES - The present invention relates to intranasally administered pharmaceutical compositions for the treatment of headaches, such as migraines. Such pharmaceutical compositions comprise benzyl alcohol or a combination of benzyl alcohol and tetracaine. The invention also relates to methods for treating headaches, such as migraines, using these pharmaceutical compositions. | 2015-09-03 |
| 20150246018 | N-ACETYL L-CYSTEINE CHELATES AND METHODS FOR MAKING AND USING THE SAME - A nutritional supplement for a human, the supplement having a chelate comprised of an N-acetyl-L-cysteine ligand bonded to zinc to form a chelate ring. A method of treating a human for one or more of oxidative stress, cardiovascular disease, cerebrovascular disease, neurodegenerative diseases, Alzheimer's disease, ADHD, bipolar, schizophrenia, autism, dementia, and HIV in a human comprising administering an effective amount of a composition having N-acetyl-L-cysteine in a chelate formation with zinc. A compound having a chelate formulation with zinc being chelated by an N-acetyl-L-cysteine ligand. | 2015-09-03 |
| 20150246019 | METHODS TO MOBILIZE PROGENITOR/STEM CELLS - Methods to elevate progenitor and stem cell counts in animal subjects using compounds which bind to the chemokine receptor CXCR4 are disclosed. Preferred embodiments of such compounds are of the formula | 2015-09-03 |
| 20150246020 | CYCLIC NITRO COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF AND USES THEREOF - The present invention provides cyclic nitro compound, pharmaceutical compositions of cyclic nitro compounds and methods of using cyclic nitro compounds and/or pharmaceutical compositions thereof to treat or prevent diseases or disorders characterized by abnormal cell proliferation, such as cancer, inflammation, cardiovascular disease and autoimmune disease. | 2015-09-03 |
| 20150246021 | PROLINE SULFONAMIDE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS - The present invention relates to (S)-proline sulfonamide compounds of formula (I), wherein R | 2015-09-03 |
| 20150246022 | BIOSTABLE, MULTIPURPOSE, MICROBICIDAL INTRAVAGINAL DEVICES - Biostable, multipurpose, microbicidal intravaginal devices in the form of rings, ringed-meshes, sponges, or diaphragms for use by women and condoms for use by male partners are provided, wherein each of the devices contains a drug effective in treating a particular vaginal infection, while further exhibiting at least one additional function selected from the group dealing with non-hormonal contraception, management of sexually transmitted diseases, viral infections, and retroviral infections as well as the treatment of cervical cancer. | 2015-09-03 |
| 20150246023 | BENDAMUSTINE DERIVATIVES AND METHODS OF USING SAME - The present invention is directed to bendamustine esters and bendamustine amides and their use for the treatment of cancer. | 2015-09-03 |
| 20150246024 | METHODS AND COMPOSITIONS FOR INHIBITING GRAM POSITIVE BACTERIA - Methods and compositions are provided for treating or preventing a Gram-positive bacteria infection using an inhibitor of lipo-teichoic acid synthase (LtaS). In some embodiments, the inhibitor is a small molecule. In certain embodiments, the inhibitor is 2-oxo-2-(5-phenyl-1,3,4-oxadiazol-2-ylamino)ethyl 2-naphtho[2,1-b]furan-1 -ylacetate, or a salt thereof. | 2015-09-03 |
| 20150246025 | 2-PHENYL-5-HETEROCYCLYL-TETRAHYDRO-2H-PYRAN-3-AMINE COMPOUNDS FOR USE IN THE TREATMENT OF DIABETES AND ITS ASSOCIATED DISORDERS - The present invention relates to novel compounds of the general formula (I) their tautomeric forms, their enantiomers, their diastereoisomers, their pharmaceutically accepted salts, or pro-drugs thereof, which are useful for the treatment or prevention of diabetes mellitus (DM), obesity and other metabolic disorders. The invention also relates to process for the manufacture of said compounds, and pharmaceutical compositions containing them and their use. | 2015-09-03 |
| 20150246026 | NOVEL QUINUCLIDINE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME - A compound according to formula (I) wherein z© is a phenyl ring, a C | 2015-09-03 |
| 20150246027 | FIXED DOSE PHARMACEUTICAL COMPOSITION COMPRISING DEFERASIROX AND DEFERIPRONE - The present invention relates to a fixed dose pharmaceutical composition comprising iron chelating agents. | 2015-09-03 |
| 20150246028 | PYRIDONE AMIDES AS MODULATORS OF SODIUM CHANNELS - The invention relates to pyridone amide compounds of formula I and I′ or pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels: | 2015-09-03 |
| 20150246029 | Positive Allosteric Modulators and Uses Thereof - The present invention relates to compounds useful in the positive modulation of the alpha 7 nicotinic acetylcholine receptor (α7nAChR). The invention also relates to the use of these compounds in the treatment or prevention of a broad range of diseases in which the positive modulation of α7nAChR is advantageous, including neurodegenerative and neuropsychiatric diseases and also inflammatory diseases. | 2015-09-03 |
| 20150246030 | Compounds Having CRTH2 Antagonist Activity - Compounds of general formula (II) | 2015-09-03 |
| 20150246031 | PHARMACEUTICAL COMPOSITION AND ADMINISTRATIONS THEREOF - The present invention relates to pharmaceutical compositions containing a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and processing the powders, granules and mini-tablets, and methods for treating cystic fibrosis employing the pharmaceutical composition. | 2015-09-03 |
| 20150246032 | PHARMACEUTICAL COMPOSITION COMPRISING REBAMIPIDE - The present invention relates to a rebamipide-containing ophthalmic composition which achieves a superior re-dispersibility and transparency by comprising various additives as well as a zinc compound as a preservative (which supplements the antiseptic-effect) in the amount which does not produce an adverse effect. | 2015-09-03 |
| 20150246033 | METHODS FOR INHIBITING TIE-2 KINASE USEFUL IN THE TREATMENT OF CANCER - The present invention relates to methods of inhibiting TIE2 kinase useful in the treatment of tumor growth, invasiveness, intravasation, dissemination, metastasis, and immunosuppression. Specifically, the invention relates to methods of using 1-(3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl)-3-(2-fluoro-4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)urea and salts thereof of Formula I. | 2015-09-03 |
| 20150246034 | PHARMACEUTICAL COMPOSITIONS FOR EXTENDED RELEASE OF OXYCODONE AND ACETAMINOPHEN RESULTING IN A QUICK ONSET AND PROLONGED PERIOD OF ANALGESIA - The present disclosure provides extended release pharmaceutical compositions comprising oxycodone and acetaminophen that produce a quick initial onset of analgesia, yet, maintain analgesia for about 12 hours after administration of the composition to a subject in need thereof. The pharmaceutical compositions disclosed herein also reduce the levels of acetaminophen in a subject's blood near the end of the dosing interval because the acetaminophen released by the pharmaceutical composition is being eliminated by a subject's body faster than it is being absorbed. | 2015-09-03 |
| 20150246035 | CRUSH-RESISTANT TABLETS INTENDED TO PREVENT ACCIDENTAL MISUSE AND UNLAWFUL DIVERSION - Water-insoluble matrix tablets which are capable of prolonged release of active principles liable to be diverted for drug addiction purposes, the said active principles being dispersed within a tabletting matrix composed of at least one excipient selected from the group consisting of pH-independent, water-insoluble delay polymers, inorganic excipients and mixtures thereof, and exhibiting a crush resistance of at least 4 MPa. | 2015-09-03 |
| 20150246036 | Morphine Formulations - Provided herein, generally, are pharmaceutical formulations, e.g., injectable pharmaceutical formulations with improved stability, comprising morphine sulfate or a hydrate thereof, and methods of producing and using the same. Also provided herein are kits comprising the formulations, e.g., injectable morphine formulations. | 2015-09-03 |
| 20150246037 | TREATMENT FOR NEURODEGENERATION - Provided is a method of treating and/or preventing Wolfram Syndrome (WS)-related neurodegeneration (i.e. of Wolfram Syndrome-Associated Neuronal Degeneration), by increasing the expression and/or functional activity of p21. A method of screening for pharmacological agents useful in treating and/or preventing such conditions is also provided. | 2015-09-03 |
| 20150246038 | TABLET FORMULATION OF A PHOSPHATIDYLINOSITOL 3-KINASE INHIBITOR - The present invention is directed to compositions and methods that target the PI3K signaling pathway for the treatment or prevention of cancer. In one aspect, there is provided a pharmaceutical formulation comprising Polymorph E of N-(3-{[(2Z)-3-[(2-chloro-5-methoxyphenyl)amino]quinoxalin-2(1H)-ylidene]sulfamoyl}phenyl)-2-methylalaninamide. | 2015-09-03 |
| 20150246039 | TREATMENT FOR VITILIGO - Compounds I and II, as well as prodrugs, hydrates, solvates, N-oxides, salts and pharmaceutical compositions containing them, are useful for treating vitiligo. In certain embodiments, the compounds are provided in topical compositions. | 2015-09-03 |
| 20150246040 | HETEROCYCLIC COMPOUNDS AND USES THEREOF - The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same. | 2015-09-03 |
| 20150246041 | COMPOUNDS AND METHODS FOR TREATING MULTIPLE SCLEROSIS - The invention described herein pertains to the treatment of multiple sclerosis. In particular, the invention described herein pertains to the treatment of multiple sclerosis using compounds that modulate the action of acrolein. | 2015-09-03 |
| 20150246042 | RAF KINASE MODULATOR COMPOUNDS AND METHODS OF USE THEREOF - Compounds, compositions and methods are provided for modulating the activity of RAF kinases, including BRAF kinase and for the treatment, prevention, or amelioration of one or more symptoms of disease or disorder mediated by RAF kinases. | 2015-09-03 |
| 20150246043 | ORAL DOSAGE FORMS FOR MODIFIED RELEASE COMPRISING RUXOLITINIB - The invention essentially relates to oral dosage forms comprising a JAK kinase inhibitor, preferably Ruxolitinib, suitable for modified release, and processes of preparing such oral dosage forms. | 2015-09-03 |
| 20150246044 | NEW THERAPEUTIC APPROACHES FOR TREATING PARKINSON'S DISEASE - The present invention relates to compositions and methods for the treatment of Parkinson's disease and related disorders. More specifically, the present invention relates to novel combinatorial therapies of Parkinson's disease and related disorders targeting the alpha-synuclein aggregation network. In particular, the invention relates to compounds which, alone or in combination(s), can effectively protect neuronal cells from alpha-synuclein aggregates. The invention also relates to methods of producing a drug or a drug combination for treating Parkinson's disease and to methods of treating Parkinson's disease or a related disorder. | 2015-09-03 |
| 20150246045 | MEDICAL USE OF A DPP-4 INHIBITOR - The present invention relates to the use of a certain DPP-4 inhibitor for use in a patient being at risk of or having heart failure with preserved ejection fraction (HFpEF). | 2015-09-03 |
| 20150246046 | JAK1 INHIBITORS FOR THE TREATMENT OF MYELODYSPLASTIC SYNDROMES - This invention relates to JAK1 selective inhibitors, particularly pyrrolo[2,3-d]pyrimidine and pyrrolo[2,3-b]pyridine derivatives, and their use in treating myelodysplastic syndromes (MDS). | 2015-09-03 |
| 20150246047 | NOVEL EGFR MODULATORS AND USES THEREOF - The present invention relates to certain pyrrolopyrimidine derivatives, pharmaceutical compositions containing them, and methods of using them, including methods for the treatment of tumors and related diseases related to the dysregulation of kinase (such as EGFR (including HER), Alk, PDGFR, but not limited to) pathways. | 2015-09-03 |
| 20150246048 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES - Described herein are pyrrolo{2,3-d}pyrimidine derivatives, their use as Janus Kinase (JAK) inhibitors, and pharmaceutical compositions containing them. | 2015-09-03 |
| 20150246049 | METHODS OF USING A METHYLXANTHINE COMPOUND - The invention relates to compositions and methods for treating various diseases or medical conditions by administering a methylxanthine compound. Specifically, the invention relates to compositions and methods for treating cytochrome oxidase (CcOX) mediated diseases or medical conditions by administering compositions comprising a methyl xanthine compound. | 2015-09-03 |
| 20150246050 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, CONTAINING ENOBLOCK AS ACTIVE INGREDIENT - The present invention relates to ENOblock, which is a non-substrate analogue having an enolase inhibitory activity, and a pharmaceutical composition for preventing or treating cancer or enolase-associated diseases, containing the same. The ENOblock of the present invention directly binds to enolase so as to inhibit an activity thereof, and the inhibition is more effective in hypoxia than in normoxia. In addition, the ENOblock of the present invention inhibits migration, metastasis and invasion of cancer cells. Furthermore, the ENOblock of the present invention induces glucose uptake into cells, down-regulates the expression of PEPCK, and inhibits adipogenesis and foam cell formation. Therefore, a composition containing the ENOblock of the present invention can be very effectively applied to prevent or treat cancer or enolase-associated diseases. | 2015-09-03 |
| 20150246051 | PHARMACEUTICAL COMPOSITION OF 1-ADAMANTYLETHYLOXY-3-MORPHOLINO-2-PROPANOL OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF FOR THE TREATMENT OF CARDIOVASCULAR DISEASE - A pharmaceutical composition for parenteral administration containing the active ingredient 1-adamantylethyloxy-3-morpholino-2-propanol, or pharmaceutically acceptable salts thereof, in a concentration range of from 3 to 100 mg/ml for the treatment of cardiovascular disease. | 2015-09-03 |
| 20150246052 | 1,2,5-SUBSTITUTED BENZIMIDAZOLES AS FLAP MODULATORS - The present invention relates to compounds of Formula (I), | 2015-09-03 |
| 20150246053 | SOLID ORAL COMPOSITIONS OF TOLVAPTAN - The present invention relates to solid dispersion compositions of tolvaptan and process for the preparation of oral dosage forms. | 2015-09-03 |
| 20150246054 | COGNITIVE FUNCTION - Provided herein are methods, drug formulations, and dosing regimens for improving cognitive function in a normal or cognitively impaired subject. For instance, methods provided herein comprise administering a GABA | 2015-09-03 |
| 20150246056 | METHODS FOR TREATING OR PREVENTING SYMPTOMS OF HORMONAL VARIATIONS - A method for treating or preventing symptoms of hormonal variation includes administering an effective amount of a receptor antagonist to a subject having one or more symptoms of hormonal variations, wherein the receptor antagonist binds to at least one selected from the group consisting of a serotonin type 2A (5-HT | 2015-09-03 |
