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35th week of 2011 patent applcation highlights part 32
Patent application numberTitlePublished
20110212363POWER STORAGE SYSTEM AND MANUFACTURING METHOD THEREFOR AND SECONDARY BATTERY AND CAPACITOR - The present invention relates to a power storage system including a negative electrode which has a crystalline silicon film provided as a negative electrode active material on the surface of a current collector and contains a conductive oxide in a surface layer section of the crystalline silicon film. Alternatively, the present invention relates to a method for manufacturing a power storage system, which includes the step of forming an amorphous silicon film on a current collector, adding a catalytic element for promoting crystallization of the amorphous silicon, onto a surface of the amorphous silicon film, heating the amorphous silicon film with the catalytic element added to crystallize the amorphous silicon film and thereby form a crystalline silicon film, and using the crystalline silicon film as a negative electrode active material layer.2011-09-01
20110212364POSITIVE ELECTRODE FOR NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY AND METHOD OF MANUFACTURING THE SAME, AND NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY USING THE POSITIVE ELECTRODE AND METHOD OF MANUFACTURING THE SAME - A positive electrode for a non-aqueous electrolyte secondary battery, having a positive electrode current collector and a positive electrode active material layer formed on the positive electrode current collector and containing LiCoO2011-09-01
20110212365Carbon-Coated Li-Containing Powders and Process for Production Thereof - The invention provides a new route for the synthesis of carbon-coated powders having the olivine or NASICON structure, which form promising classes of active products for the manufacture of rechargeable lithium batteries. Carbon-coating of the powder particles is necessary to achieve good performances because of the rather poor electronic conductivity of said structures. For the preparation of coated LiFePO2011-09-01
20110212366Non-aqueous electrolyte secondary battery - A non-aqueous electrolyte secondary battery has a positive electrode containing a positive electrode active material, a negative electrode containing a negative electrode active material, and a non-aqueous electrolyte. The positive electrode active material includes a lithium-nickel-manganese composite oxide having a hexagonal layered rock-salt structure that belongs to the space group R-3m, and contains lithium in 3b sites that contain transition metals. The lithium-nickel-manganese composite oxide is represented by the molecular formula Li[Li2011-09-01
20110212367Non-aqueous electrolyte secondary battery - A non-aqueous electrolyte secondary battery has a positive electrode containing a positive electrode active material, a negative electrode containing a negative electrode active material, and a non-aqueous electrolyte. The positive electrode active material includes a lithium-nickel-manganese composite oxide having a hexagonal layered rock-salt structure that belongs to the space group R-3m, and contains lithium in 3b sites that contain transition metals. The lithium-nickel-manganese composite oxide is represented by the molecular formula Li[Li2011-09-01
20110212368ROLLED ELECTRODE FOR A STORAGE BATTERY - The invention relates to a rolled electrode for a storage battery, wherein the electrode (2011-09-01
20110212369PRESSING-TYPE CYLINDRICAL METAL AIR BATTERY - The present invention relates to a metal air battery for improving storage performance. The present invention provides a pressing-type cylindrical metal air battery which comprises: an external case which is formed in a cylindrical shape, and has a cathode terminal on one side and an anode terminal hole on the other side; an internal case which is formed in a cylindrical shape and coaxially inserted into the inside of the external case, has an anode terminal that is inserted into or extracted from the inside or the outside of the anode terminal hole on one side, and has an air inflow hole on the surface of a wall so that air can flow into the air inflow hole; and an elastic sealing means which is formed on the one side of the internal case, enables the air to flow into the anode terminal hole by elastically pressurizing the anode terminal when a battery is inserted into a battery compartment, and seals the anode terminal hole by elastically restoring the anode terminal again if the battery is separated from the battery compartment. Because the invention has a double structure comprised of the external case and the internal case, the air inflow hole of the internal case can be opened to or sealed from the outside when the battery is inserted into or separated from the battery compartment, thereby easily blocking the inflow of the air if the battery is not in use. Consequently, the present invention has the advantage of improving the storage performance by reducing natural discharge of the battery.2011-09-01
20110212370Systems and Methods of Securing Immunity to Air CO2 in Alkaline Fuel Cells2011-09-01
20110212371FUEL CELL SYSTEM - A fuel cell system includes a fuel cell; a circulating system that circulates and supplies fuel off-gas discharged from the fuel cell to the fuel cell; a pump that pumps a fluid in the circulating system; a discharge valve through which the fluid in the circulating system is discharged to the outside; and a control device that controls the pump and the discharge valve. If operation of the fuel cell is started in a cold environment, the control device executes a control to start power generation in the fuel cell for a first period before activating the pump and executes a control to drive the pump while the discharge valve is closed for a second period.2011-09-01
20110212372Motion fuel cell - A fuel cell system (with reference to a single cell arrangement) comprising means to provide for the reciprocating, oscillating and or vibrational motion-movement of an assembly comprised of an electrolyte sandwiched between an anode-electrode and a cathode-electrode; said motion-movement serving to accelerate electrochemical activity within the fuel cell by providing for accelerated reactant exposure to respective electrodes; including instant water removal at the cathode-electrode surface; and boosted cooling to said anode-electrode; while offering accelerated (anti electroosmotic) moisturizing to the specific benefit of the anode side of a polymer electrolyte.2011-09-01
20110212373Hydrogen generator - Hydrogen generation materials are a complex hydride which generates hydrogen upon hydrolysis, and an aqueous solution comprising water for causing the hydrolysis, and an accelerator dissolved therein for accelerating a hydrogen generation reaction. A method of hydrogen generation by a hydrogen generator comprises a first step S2011-09-01
20110212374Hydrogen-Generating Fuel Cell Cartridges - The present application is directed to a gas-generating apparatus (2011-09-01
20110212375HYDROGEN GENERATOR AND FUEL CELL SYSTEM COMPRISING THE SAME - A hydrogen generator of the present invention includes a reformer (2011-09-01
20110212376AMPEROMETRIC SENSOR - A carbon monoxide sensor includes a housing providing an analyte inlet. Multiple electrodes are arranged in the housing and include a sensing electrode in communication with the analyte inlet. The sensing electrode includes a catalytic material niobium that is configured to oxidize carbon monoxide. Output elements are connected to the electrodes and are configured to provide a carbon monoxide signal in response to an analyte reacting with the sensing electrode.2011-09-01
20110212377FUEL CELL SYSTEM AND MOBILE ARTICLE - There is disclosed a fuel cell system including a fuel cell, a fuel supply system to supply a fuel gas to the fuel cell, an injector which adjusts a gas state on an upstream side of the fuel supply system to supply the gas to a downstream side, and a control unit which drives and controls the injector in a predetermined drive cycle. The control unit sets the drive cycle of the injector in accordance with an operation state of the fuel cell.2011-09-01
20110212378FUEL CELL ARRANGEMENT WITH FUEL CELLS DISPOSED IN A SHINGLE CONSTRUCTION AND ALSO PURPOSES OF USE - The present invention relates to a fuel cell arrangement which comprises at least two single fuel cells, the single fuel cells being disposed non-parallel to each other, i.e. being disposed offset or in a shingle construction relative to each other.2011-09-01
20110212379METHOD OF FORMING A FUEL CELL SHEET - An example method of forming a fuel cell sheet includes flattening a screen to form a sheet that has a plurality of apertures operative to communicate a fluid within a fuel cell.2011-09-01
20110212380FUEL CELL STACK ENCLOSURE - A fuel cell device including a fuel cell stack with a flexible enclosure.2011-09-01
20110212381FUEL CELL - A fuel cell comprising: a membrane electrolyte assembly having a polymer electrolyte membrane and a pair of catalyst electrodes, namely an air electrode and a fuel electrode sandwiching the polymer electrolyte membrane; a pair of separators, namely an air electrode separator and a fuel electrode separator sandwiching the membrane electrolyte assembly; two or more oxidizing gas channels running in a certain direction for the purpose of supplying an oxidizing gas to the air electrode; and two or more linear fuel gas channels arranged parallel to the certain direction for the purpose of supplying a fuel gas to the fuel electrode. Large gaps and small gaps are provided alternately between adjacent two oxidizing gas channels along the certain direction, and the fuel gas channels do not overlap portions of the oxidizing gas channels, that are parallel to the fuel gas channels.2011-09-01
20110212382High energy density ionic dielectric materials and devices - Dielectric compositions that include compound of the formula [(M′)2011-09-01
20110212383LIQUID COMPOSITION, PROCESS FOR ITS PRODUCTION, AND PROCESS FOR PRODUCING MEMBRANE-ELECTRODE ASSEMBLY FOR POLYMER ELECTROYLTE FUEL CELLS - An electrolyte membrane is prepared from a liquid composition comprising at least one member selected from the group consisting of trivalent cerium, tetravalent cerium, bivalent manganese and trivalent manganese; and a polymer with a cation-exchange group. The liquid composition is preferably one containing water, a carbonate of cerium or manganese, and a polymer with a cation-exchange group, and a cast film thereof is used as an electrolyte membrane to prepare a membrane-electrode assembly. The present invention successfully provides a membrane-electrode assembly for polymer electrolyte fuel cells being capable of generating the electric power in high energy efficiency, having high power generation performance regardless of the dew point of the feed gas, and being capable of stably generating the electric power over a long period of time.2011-09-01
20110212384ANODE CATALYSTS FOR FUEL CELL MEMBRANE REACTORS - Anode catalysts for conversion of hydrocarbon feeds in solid oxide fuel cell membrane reactors. An anode catalyst may be a mixture of a metal with a metal oxide, for example a mixture of copper or copper-nickel alloy or copper-cobalt alloy with Cr2011-09-01
20110212385FUEL CELL SEPARATOR AND FUEL CELL - A fuel cell separator comprises a first plate and a second plate. The first plate has a plurality of first projections protruded toward the second plate to define reactive gas flow paths, the second plate has a plurality of second projections protruded toward the first plate to define reactive gas flow paths. A top of each of the plurality of first projections is in contact with an intermediate part between adjacent two of the plurality of second projections formed on the second plate, and a top of each of the plurality of second projections is in contact with an intermediate part between adjacent two of the plurality of first projections formed on the first plate.2011-09-01
20110212386CATALYTIC MATERIALS FOR FUEL CELL ELECTRODED AND METHOD FOR THEIR PRODUCTION - Layered catalyst structures for fuel cells, particularly for a Proton Exchange Membrane Fuel Cell (PEMFC), are produced by a reactive spray deposition technology process. The catalyst layers so produced contain particles sized between 1 and 15 nm and clusters of such particles of a catalyst selected from the group consisting of platinum, platinum alloys with transition metals, mixtures thereof and non-noble metals. The catalyst layers without an electrically conducting supporting medium exhibit dendritic microstructure, providing high electrochemically active surface area and electron conductivity at ultra-low catalyst loading. The catalyst layers deposited on an electrically conducting medium, such as carbon, exhibit three-dimensional functional grading, which provides efficient utilization as a catalyst, high PEMFC performance at the low catalyst loading, and minimized limitations caused by reactant diffusion and activation. The catalytic layers may be produced by a single-run deposition method.2011-09-01
20110212387Volume Hologram Comprising Expansion Agent Layer or Contraction Agent Layer for Creating Color Patterns - The invention concerns a security element in the form of a multi-layer film body having a volume hologram layer with two different items of optical information and a process for the production of such a security element.2011-09-01
20110212388ADVANCED PHASE SHIFT LITHOGRAPHY AND ATTENUATED PHASE SHIFT MASK FOR NARROW TRACK WIDTH D WRITE POLE DEFINITION - A method for patterning a wafer using a phase shifting photolithography that can produce a critical symmetrical 2-dimensional structure such as a magnetic write pole of a magnetic write head. In one aspect of the invention, a photolithographic mask has an opaque portion with narrow, transparent phase shifting regions at either side of the opaque portion. A non-phase shifted region extends beyond the narrow phase shifted portion at either side of the structure. The phase shifted regions are symmetrical about the opaque region so that the image produced on the wafer is completely symmetrical. In another aspect of the invention, a phase shifted region in formed in a transparent medium with non-phase shifted regions at either side of the phase shifted region. The transition between the phase shifted region and non-phase shifted region alone defines a pattern on the wafer, without the need for an opaque structure on the mask.2011-09-01
20110212389FOCUS TEST MASK, FOCUS MEASUREMENT METHOD, EXPOSURE METHOD AND EXPOSURE APPARATUS - A focus test reticle for measuring focus information includes an outer pattern. The outer pattern has a line pattern composed of a light shielding film extending in the Y direction, a phase shift portion provided on a side in the +X direction of the line pattern and formed to have a line width narrower than the line pattern, a transmitting portion provided on a side in the −X direction of the line pattern and formed to have a line width narrower than the line pattern, a transmitting portion provided on a side in the +X direction of the phase shift portion, and a phase shift portion provided on a side in the −X direction of the transmitting portion. Focus information of a projection optical system is measured at a high measuring reproducibility and a high measuring efficiency.2011-09-01
20110212390CHEMICALLY AMPLIFIED NEGATIVE RESIST COMPOSITION AND PATTERNING PROCESS - A chemically amplified negative resist composition is provided comprising (A) an alkali-soluble base polymer, (B) an acid generator, and (C) a nitrogen-containing compound, the base polymer (A) turning alkali insoluble under the catalysis of acid. A polymer having a fluorinated carboxylic acid onium salt on a side chain is included as the base polymer. Processing the negative resist composition by a lithography process may form a resist pattern with advantages including uniform low diffusion of acid, improved LER, and reduced substrate poisoning.2011-09-01
20110212391POLYMER, CHEMICALLY AMPLIFIED POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS - A polymer comprising recurring units having a fluorinated carboxylic acid onium salt structure on a side chain is used to formulate a chemically amplified positive resist composition. When the composition is processed by lithography to form a positive pattern, the diffusion of acid in the resist film is uniform and slow, and the pattern is improved in LER.2011-09-01
20110212392PHOTOMASK BLANK, PHOTOMASK, AND METHODS OF MANUFACTURING THE SAME - A photomask blank is for use in manufacturing a photomask to be applied with exposure light having a wavelength of 200 nm or less. The photomask blank has a light-transmitting substrate and a light-shielding film formed thereon. The light-shielding film has a light-shielding layer containing a transition metal and silicon and a front-surface antireflection layer formed contiguously on the light-shielding layer and made of a material containing at least one of oxygen and nitrogen. The light-shielding film has a front-surface reflectance of a predetermined value or less for the exposure light and has a property capable of controlling the change width of the front-surface reflectance at the exposure wavelength to be within 2% when the thickness of the front-surface antireflection layer changes in the range of 2 nm. The material of the front-surface antireflection layer having a refractive index n and an extinction coefficient k capable of achieving such property is selected.2011-09-01
20110212393METHODS FOR MANUFACTURING PIXEL UNIT, LIQUID CRYSTAL DISPLAY PANEL, AND ELECTRO-OPTICAL APPARATUS - A pixel unit having a display area is provided. The pixel unit includes a first substrate, a second substrate, a liquid crystal layer, and at least one ultraviolet light (UV) absorption pattern. The second substrate is disposed in parallel to the first substrate, and the liquid crystal layer is disposed between the first substrate and the second substrate. The UV absorption pattern is disposed between the first substrate and the second substrate. A part of the display area overlaps the UV absorption pattern to define at least one first alignment area, while the part of the display area which does not overlap the UV absorption pattern defines at least one second alignment area. The liquid crystal molecules of the liquid crystal layer present different pre-tilt angles in the first alignment area and the second alignment area.2011-09-01
20110212394EXPOSURE APPARATUS, MEASUREMENT METHOD, STABILIZATION METHOD, AND DEVICE FABRICATION METHOD - The present invention provides an exposure apparatus including a projection optical system configured to project a reticle pattern onto a wafer, a selector configured to select a dummy wafer to be placed near an image plane of the projection optical system, from a plurality of dummy wafers having the same shape as that of the wafer and different reflectance with each other, a transfer unit configured to place the dummy wafer selected by the selector near the image plane of the projection optical system, and a controller configured to perform control such that dummy exposure is performed by irradiating the dummy wafer, which is placed near the image plane of the projection optical system by the transfer unit, with light via the projection optical system.2011-09-01
20110212395ELECTROPHOTOGRAPHIC TONER - A resin binder for use in a toner for electrophotography, containing a polycondensation resin obtainable by polycondensing an alcohol component containing an aliphatic polyhydric alcohol having two or more secondary carbon atoms with a hydroxyl group bound thereto (an alcohol A), and a carboxylic acid component, wherein the alcohol A is contained in an amount of from 10 to 100% by mol, of the alcohol component; and a toner for electrophotography containing the resin binder. The toner for electrophotography of the present invention is suitably used in developing latent images formed in electrophotography, electrostatic recording method, electrostatic printing method or the like.2011-09-01
20110212396BIO-BASED AMORPHOUS POLYESTER RESINS FOR EMULSION AGGREGATION TONERS - Disclosed are amorphous polyesters that contain only renewable resources designed for emulsion aggregation toner fabrication. The amorphous polyesters may be obtained from the mixture of three different monomers: 1,4:3,6-dianhydro-D-sorbitol (isosorbide), nonanedioic acid (azelaic acid), and butanedioic acid (succinic acid). Different polymer properties may be achieved depending on the ratio of these three monomers. By altering the ratio, polymers of high to low acid value can be obtained, as well as different ranges of glass transition temperatures.2011-09-01
20110212397ELECTROPHOTOGRAPHIC TONER - An electrophotographic toner, which is decolorized by heating and a glossiness after decolorization of which is less than 10, comprising an electron donating color former compound, an electron accepting color developing agent, and a polyester binder resin.2011-09-01
20110212398TONER FOR DEVELOPING ELECTROSTATIC LATENT IMAGES AND PRODUCTION METHOD OF THE SAME - A toner for developing electrostatic latent images, including a binder resin, and a colorant, wherein the binder resin includes an amorphous resin obtained from a radical polymerizable monomer unit containing a styrene type monomer and a (meth)acrylic ester type monomer and a crystalline resin, and a ratio (Q2011-09-01
20110212399FERRITE CORE MATERIAL AND FERRITE CARRIER FOR ELECTROPHOTOGRAPHIC DEVELOPER, AND ELECTROPHOTOGRAPHIC DEVELOPER USING THE FERRITE CARRIER - There is provided a ferrite core material for an electrophotographic developer, the ferrite core material having a ferrite particle composition represented by the formula (1) shown below, containing SrO replacing a part of (MnO) and/or (MgO) in the formula (1) shown below, and having a Cl concentration of 0.1 to 100 ppm, as measured by an elution method of the ferrite core material:2011-09-01
20110212400LASER INDUCED THERMAL IMAGING APPARATUS AND LASER INDUCED THERMAL IMAGING METHOD - A laser induced thermal imaging apparatus for imaging an imaging layer of a donor film on an acceptor substrate. The laser induced thermal imaging apparatus includes: a substrate stage having an electromagnet, and adapted to receive an acceptor substrate having a pixel area of the organic light emitting device and a donor film including the organic light emitting layer to be imaged on the pixel area; a laser oscillator for irradiating a laser on the donor film; a contact frame adapted to be located between the substrate stage and the laser oscillator and including an opening portion of a pattern corresponding to a part to be imaged of the donor film and a permanent magnet for forming a magnetic force with the substrate stage; and a contact frame moving mechanism for moving the contact frame toward the substrate stage.2011-09-01
20110212401RADIATION-SENSITIVE RESIN COMPOSITION, AND RESIST PATTERN FORMATION METHOD - A radiation-sensitive resin composition includes a resin, a photoacid generator, a fluorine-containing resin, and a lactone compound. The resin does not include a first fluorine-containing repeating unit. The resin includes a first repeating unit that becomes alkali-soluble due to an acid. The fluorine-containing resin includes a second fluorine-containing repeating unit and a second repeating unit that becomes alkali-soluble due to an acid. A content of the lactone compound in the radiation-sensitive resin composition is about 31 to about 200 parts by mass based on 100 parts by mass of the resin.2011-09-01
20110212402PHOTOSENSITIVE RESIN COMPOSITION AND ITS APPLICATION - A photosensitive resin composition comprising: 2011-09-01
20110212403METHOD AND APPARATUS FOR ENHANCED DIPOLE LITHOGRAPHY - Provided is a lithography system that includes a source for providing energy, an imaging system configured to direct the energy onto a substrate to form an image thereon, and a diffractive optical element (DOE) incorporated with the imaging system, the DOE having a first dipole located in a first direction and a second dipole located in the first direction or a second direction perpendicular the first direction. The first dipole includes a first energy-transmitting region spaced a first distance from a center of the DOE. The second dipole includes a second energy-transmitting region spaced a second distance from the center of the DOE. The first distance is greater than the second distance.2011-09-01
20110212404AUTOMATED SETUP PROCESS FOR METERED COMBUSTION CONTROL SYSTEMS - A method is provided for the automated setup of a metered combustion control system for controlling operation of a boiler combustion system. The automated setup process includes both commissioning and controller tuning, rather than tuning the carbon monoxide and/or oxygen trim controller after the commissioning process has been completed. The oxygen trim controller or the carbon monoxide trim controller is used to identify the air/fuel ratio.2011-09-01
20110212405METHOD FOR THE PRODUCTION OF ULTRAPURE PHOSPHORUS BY ZONE MELTING IN A NON-FLAMMABLE ENVIRONMENT, AND THE APPARATUS USED IN SUCH METHOD - In general, the present invention relates to the production of ultrapure phosphorus. In particular, the present invention relates to the method for the production of ultrapure phosphorus by zone melting in a Non-flammable environment and the equipments used in such method. The process of the present invention is clean, chemical free, fast, and energy efficient.2011-09-01
20110212406HOT MELT DENTAL MATERIALS AND DEVICES AND METHODS FOR USING THE SAME - Example embodiments of the present invention include hot melt dental adhesive materials that can create a reversible bond. In addition, example embodiments of the present invention include hot melt dental impression materials that can be used to accurately and efficiently obtain a dental impression. Moreover, example embodiments of the invention include devices and methods for use with the hot melt dental adhesive materials and the hot melt dental impression materials disclosed herein. The hot melt dental adhesive materials and the hot melt dental impression materials can provide dental professionals with dental materials that are more effective, efficient, and easier to use when compared to conventional dental adhesive materials and conventional dental impression materials.2011-09-01
20110212407SELF-LIGATING ORTHODONTIC BRACKET ASSEMBLY - A clip for a self-ligating orthodontic bracket assembly has a lifting element between the labial surface of the bracket and the labial portion of the clip that can be rotated to provide a range of adjustability in lifting the labial portion of the clip with respect to the bracket. The lifting element thereby controls the range of motion of the tongue of the clip in its closed position. This limits the forces applied by the clip to an archwire held in the archwire slot of the bracket, and also allows an archwire to slide freely in the slot. A threaded shaft or camming mechanism can be employed as the lifting element.2011-09-01
20110212408Buccal tube with square or rectangular auxiliary slot - A buccal tube with a square or rectangular auxiliary slot/tube is provided. The square or rectangular auxiliary slot/tube allows for the attachment of auxiliaries of similar shapes, and thus prevents rotation of square or rectangular auxiliary within the buccal tube. An orthodontic auxiliary such as a headgear facebow, which is round, can still be inserted into the square or rectangular buccal tube so long as the size of the headgear facebow is smaller than the smallest inside dimension of the buccal tube.2011-09-01
20110212409HOT MELT DENTAL MATERIALS AND DEVICES AND METHODS FOR USING THE SAME - Example embodiments of the present invention include hot melt dental adhesive materials that can create a reversible bond. In addition, example embodiments of the present invention include hot melt dental impression materials that can be used to accurately and efficiently obtain a dental impression. Moreover, example embodiments of the invention include devices and methods for use with the hot melt dental adhesive materials and the hot melt dental impression materials disclosed herein. The hot melt dental adhesive materials and the hot melt dental impression materials can provide dental professionals with dental materials that are more effective, efficient, and easier to use when compared to conventional dental adhesive materials and conventional dental impression materials.2011-09-01
20110212410PHOTOTHERAPY METHOD FOR TREATING PSORIASIS - A system and method for phototherapy, including skin tanning, lupus phototherapy, teeth whitening, hair growth and psoriasis therapies, are provided. The system includes a chamber adapted for at least one type of phototherapy and at least one UV LED, at least one nanostructure UV light emitting device or a combination of UV LEDs and nanostructure UV light emitting devices.2011-09-01
20110212411SYSTEM AND METHOD FOR OPTICAL FIBER DIFFUSION - An optical fiber diffusion system and a method of manufacturing an optical fiber diffusion device that has a precisely-controlled emission region are disclosed. An optical fiber diffusion device is produced by subjecting a light emission region of an optical fiber to a series of controlled cycles of stress, heating, elongation and cooling, resulting in a pattern of deformation and modification of the fiber and cladding.2011-09-01
20110212412DISPENSING ASSEMBLIES, ARRAYS AND SYSTEMS FOR DENTAL ARTICLES - Dispensing assemblies for dental articles such as orthodontic brackets include a supply tube having a generally omega-shaped configuration. The supply tube receives a carrier strip as well as a number of containers that are releasably connected to the carrier strip. A dispenser array includes a plurality of supply tubes that are coupled to a spline by connectors. A dispensing system includes a mechanism for selectively positioning an array of supply tubes in either an upright orientation for storage or alternatively in an inclined orientation for dispensing.2011-09-01
20110212413ROTARY ENDODONTIC FILE WITH FRICTIONAL GRIP - An endodontic file has at least a central longitudinal cord, a helically wound wire at least partially surrounding the cord and an elastomeric grip partially covering the helically wound wire near a first end thereof. The elastomeric grip has an outer diameter that is slightly wider than an internal diameter of a barrel of a dental instrument whereby on insertion into the barrel it is supported therein only by friction.2011-09-01
20110212414METHOD FOR RESTORING MISSING TOOTH AND METHOD FOR PRODUCING RESTORATIVE MATERIAL - A method of producing a restorative material used to restore a tooth-deficient area in an oral cavity, the method comprising: positioning, in a support carrier, a first cell mass formed from either mesenchymal cells or epithelial cells and a second cell mass formed from the other of the mesenchymal cells or epithelial cells, one of the mesenchymal cells or epithelial cells being derived from a tooth germ and the first and second cell masses being not mixed with each other but made to closely contact each other; culturing the first and second cell masses to form a reconstructed tooth germ or tooth; and confirming directionality of the reconstructed tooth germ or tooth formed by the culturing so as to enable the reconstructed tooth germ or tooth to be embedded in the tooth-deficient area such that a tip of the tooth faces an interior of the oral cavity, the tooth germ or tooth whose directionality has been confirmed being used as a restorative material to obtain an equivalent of a missing tooth in the tooth-deficient area. A method for restoring a tooth-deficient area, the method comprising; embedding the reconstructed tooth germ or tooth obtained by the production method in the tooth-deficient area.2011-09-01
20110212415SINUS LIFT IMPLANT - A dental implant is provided that has a proximal-most part, a lateral external surface, and a distal implant portion that extends from a distal implant end along up to 50% of a longitudinal length of the implant. The implant is shaped so as to define a lumen therethrough (a) having at least one distal opening through a distal external surface of the distal implant portion, (b) having a lateral opening through the lateral external surface, and (c) not open to a proximal external surface of the implant within 2 mm of the proximal-most part of the implant. Other embodiments are also described.2011-09-01
20110212416IMPLANT HAVING CIRCUMFERENTIALLY ORIENTED ROUGHNESS - A self-tapping implant includes a shaft including a coronal end, an apical end, an outer surface having a first axial section and a second axial section, and a self-tapping configuration at the first axial section. The first axial section may be located coronally of the second axial section. Each of the first and second axial sections may include a series of peaks being axially spaced apart by troughs. In addition, the axial spacing between the adjacent peaks in the first axial section may be different than the axial spacing between adjacent peaks in the second axial section. A coronal end portion of the shaft may include the first axial section of the outer surface, and an apical end portion of the shaft may include the second axial section of the outer surface.2011-09-01
20110212417INSERTION PART OF A TWO-PART IMPLANT WITH INSERTION INSTRUMENT - The invention provides a method for inserting an insertion part of a two-part zirconium-like implant into the jawbone at high force without breaking in order in this way to increase the primary stability of the implant in the jawbone. This is made possible by providing an insertion part at the outside of two or more protrusions at the level of the jawbone line over which an insertion instrument with recesses fits which engages these protrusions in order to subsequently insert the insertion part into the jawbone. The sleeve-shaped insertion instrument with the recesses and the neck of the insertion part with the two or more protrusions can be shaped in such a way that they fit precisely together or that a connection resembling a cardan coupling is produced, so that the implantologist can hold the insertion instrument in various positions above the insertion part while the desired direction of insertion is still maintained.2011-09-01
20110212418METHODS FOR FORMING TOOTH ROOT AND PERIODONTAL TISSUE UNIT, AND REGENERATED TOOTH - A method for forming at least a tooth root in a tooth containing a tooth crown, including: forming a culture core containing the tooth and a cell-containing base material, the tooth being wrapped with the cell-containing base material, and culturing the culture core in a medium to form at least the tooth root in the tooth contained therein, wherein the cell-containing base material contains at least one kind of cells selected from periodontal ligament-derived cells, bone marrow-derived cells, dental follicle-derived cells, dental pulp-derived cells and dental papilla-derived cells, and the medium contains a component contained in a conditioned medium of a serum-free-cultured cell line of a human uterocervical squamous carcinoma cell line; an additive containing at least one selected from IL-1β, IL-6, IL-8, IL-9, EGF, IGF-I, GH, PDGF-AB, VEGF, LIF, HGF, FGF-2, FGF-1, BMP-2, BMP-4, M-CSF, dexamethasone, insulin, thyroxine, thyrocalcitonin, ascorbic acid and β-glycerophosphate; or both of them.2011-09-01
20110212419METHOD, APPARATUS AND COMPUTER PROGRAM FOR PRODUCING A DENTAL PROSTHESIS - A method for producing a tooth replacement and corresponding computer programs and devices are described. The method can comprise generating a tooth replacement having a core and an outer layer which define a boundary surface between each other. To ensure that the prepared tooth replacement is technically acceptable independent of skills and experience of the user and approximate the appearance of a natural tooth, the extension of the boundary surface represents a natural extension of the dentino-enamel junction of a tooth for which the tooth replacement is provided, wherein the extension of the boundary surface (i) is determined based on a recording of the dentino-enamel junction of the tooth for which the tooth replacement is provided, and/or (ii) is determined based on directly or indirectly recorded geometry data of at least a portion of the outer geometry of the tooth for which the tooth replacement is provided.2011-09-01
20110212420Method for dental restoration and related kit - The disclosure generally relates to a method for forming a dental mold. The method generally includes: (a) scanning an existing dental structure to generate a three-dimensional first digital model of the existing dental structure, (b) modifying the first digital model of the existing dental structure to generate a three-dimensional second digital model of a planned dental structure; (c) generating a three-dimensional third digital model corresponding to a negative of the second digital model; (d) digitally sectioning the third digital model into at least one buccal model portion and at least one lingual model portion of the third digital model; and (e) creating a dental mold comprising at least one buccal mold portion and at least one lingual mold portion based on the sectioned third digital model. The disclosure also relates to (a) methods of assembling the dental mold over a tooth and a gum of a patient having an existing dental structure in need of dental restoration, (b) methods of performing a dental restoration on the existing dental structure of the patient using the dental mold, and (c) kits including components for forming the dental mold and/or for performing the dental restoration using the dental mold.2011-09-01
20110212421THERMOCHROMATIC INKS, PRINTING METHODS AND KITS - The present invention relates to thermochromatic inks. The present invention provides a toy, wherein the toy includes at least one thermochromatic ink. The present invention provides a pre-printed item, wherein when the temperature of the pre-printed item is changed to particular temperatures, the color of a marking, the color of a drawing, or both, change. The present invention provides an interactive item, wherein the visual appearance of the item is changed by changing the color of at least one of a first or second inks. The present invention provides a drawing device, wherein the position of a substrate and a temperature element are such that a thermochromatic ink does not change color unless sufficient pressure is applied to the substrate effective to deflect the surface of the substrate and bring it temporarily sufficiently more proximate to the temperature element. The present invention provides a smart wand for drawing on a substrate that includes thermochromatic ink. The present invention provides a backlight system. The present invention provides a light box.2011-09-01
20110212422Cognitive Capacity Assessment System - Systems and methods for cognitive assessment are provided that test a subject's cognitive capacity using a battery of tests that are selected with respect to a specific job that the subject is expected to perform. The test results are analyzed based upon the relative criticality of each cognitive ability that is required by the job to provide an overall assessment of the subject's cognitive capacity to perform the job. Predictions about the subject's future capacity to perform the job can also be made by analysis of expected workload and recovery schedules.2011-09-01
20110212423Adjustable Multi-Sensory Fly Casting Trainer and Teaching Method - A fly casting training apparatus includes a shaft, a ball movable within the shaft, and adjustable limit stops for setting the range of motion of the ball within the shaft. The apparatus is used to simulate a fly casting experience, with the limit stops adjustable to simulate long casting motions, short casting motions, and casting motions therebetween. The device also includes an elastic band that may be used to simulate the double haul casting method.2011-09-01
20110212424Personal Fitness Trainers Online - The present invention method provides personal fitness trainers online training method, for use across an electronic communications network transmitting messages, exercise routines, videos, usage of the Internet and web pages “web sessions” for video and audio streaming between the personal trainer and the client one on one. The online personal fitness is a method for a database of personal trainers whom become members of the named business “Fitness Is Online” or any named business, individually consulting individual user clients, and providing all aspects of the fitness plan online, particularly email custom personalized exercise routines, workouts. The method for all purpose's including muscle building, muscle toning, cardio, aerobics, health tips, diet plans, follow up evaluation, feedback, personal workout videos, one on one web sessions, and other applicable actions implemented by the personal trainer, all personal, one on one to a client, not computer generated.2011-09-01
20110212425Modular Educational Device - A modular educational device includes primary and secondary modular boundary segments each having an outer shell extending to terminate at two socket ends, a plurality of modular plug-ended connectors each having two plug ends configured to mate with the corresponding ones of primary and secondary socket ends so as to enable the primary and secondary outer shell to form a loop-shaped structure that encircles an enclosed space of a certain geometric shape, and a modular support stand having a base and a pair of jaws which extend uprightly from the base and which are spaced apart from each other by a fitting space for accommodating a gripped region of the primary modular boundary segment so as to enable the loop-shaped structure to be stood on a surface.2011-09-01
20110212426Simulation system for training in endoscopic operations - A simulation system for training in endoscopic operations includes an endoscope apparatus, including at least one input for inserting an endoscopic working instrument, a sensor arrangement to detect a movement of the endoscopic working instrument, a control device to generate a virtual image of an endoscopic operation scene depending on a movement of the endoscopic working instrument, transmission means to transmit measured values supplied by the sensor arrangement to the control device for use in generating the virtual image and a display device to display the virtual image, where the sensor arrangement includes at least one optic sensor that interacts with a surface of a shaft of the endoscopic working instrument to detect the movement of the endoscopic working instrument. A flexible endoscope, an endoscopic working instrument and a method for recording a movement of an endoscopic working instrument as well as a method for training in endoscopic operations.2011-09-01
20110212427Surgical-Training Device for Providing Three-dimensional-Tactile Feedback, and Method of Operation Thereof - A surgical-training device for measuring roughness (non-delicate manipulation) during a simulated-surgical technique is described. The device has a housing, a platform, and a sensor module. The platform is movably coupled to the housing, and is configured for three-dimensional motion relative to the housing. The platform is further configured to move from a start position to a displaced position when a force is applied to the platform as a result of a user performing a simulated-surgical technique on the platform. A sensor module, coupled to the housing, is configured to determine when the platform moves a distance (from the start position to the displaced position) that exceeds a preset-threshold distance. If the preset-threshold distance is exceeded, sensor module indicates (by visual and/or auditory alarms within the device, and/or computerized counting and scoring reports) that the user applied excessive force, and was therefore too rough when performing the simulated-surgical technique. A method of manufacturing a surgical-training device is also provided.2011-09-01
20110212428System for Training - The present invention provides for a teaching module having a training scenario database, an editor component, a student component and an artificial intelligence component. The training scenario database has a plurality of video clips, audio files and associated artificial intelligence metadata to simulate a person's personality and mood. The editor component facilitates the creation of a training scenario involving a simulated person. The student component facilitates the interaction with the training scenario by a user. The artificial intelligence component alter the simulated person's personality and mood based on the interaction by the user to provide realistic responses allowing the user to learn how to respond to the simulated person to achieve a desired result. The teaching can be located in a single computer or over a network of computers.2011-09-01
20110212429PRINTED ARTICLE - Apparatus comprise a printed article (2011-09-01
20110212430TEACHING AND LEARNING SYSTEM - A teaching and learning system includes a data store and a server computing device. The server computing device is programmed to retrieve digital data from the data store and to generate and transfer digital data across a network to user computing devices associated with users. The digital data is configured to be interpreted by the user computing devices to display to the users an interactive web site, the web site including a plurality of learning packets. Each learning packet includes a title and multiple content sections. The title includes a text description of a topic associated with an academic topic. The multiple content sections include at least one content window, where each content window includes content having a content type selected by the author of the learning packet from a plurality of different available content types. The content of each content section includes information to teach the user about the topic identified in the title.2011-09-01
20110212431FLUIDICS BASED PULSATILE PERFUSION PRESERVATION DEVICE AND METHOD - In one embodiment, a preservation apparatus is described that includes a storage compartment. The storage compartment is configured to hold an organ or tissue and a preservation fluid. A cover assembly is configured to engage the storage compartment. The cover assembly includes a support element, wherein the support element together with the storage compartment define a storage chamber. The cover assembly also includes a lid and a gas permeable membrane disposed between the lid and the support element. The gas permeable membrane and the support element together define a perfusion chamber configured to hold preservation fluid and an organ or tissue during use.2011-09-01
20110212432SEPARATION OF BLOOD CELLS FROM A BLOOD SAMPLE - Provided is a method for the separation of blood cells from a blood sample, which method comprises: 2011-09-01
20110212433ALCOHOL PRODUCTION PROCESS - The invention relates to the production of products such as alcohols and acids by microbial fermentation, particularly microbial fermentation of substrates comprising CO. It more particularly relates to methods and systems for improving efficiency of production products by microbial fermentation. In particular embodiments, the invention provides a method of controlling substrate supply, such that production of desired metabolites is optimised.2011-09-01
20110212434NOVEL HIV-BASED RECOMBINANT VIRAL CLONES AND USE THEREOF IN ANALYTICAL METHODS - The present invention refers to HIV-based recombinant viral clones that possess the general structure represented in FIG. 2011-09-01
20110212435Antimicrobial Compounds - The compounds disclosed herein are isoxazole derivatives that are useful as antimicrobial compounds, particularly as anti-bacterial compounds. The disclosed methods comprise incubating at least two different substrates in the presence of at least one oxygenase to provide the disclosed compounds, or to prepare and identify compounds that have antimicrobial activity.2011-09-01
20110212436MOLECULAR REDUNDANT SEQUENCING - Methods, systems and compositions where a target nucleic acid includes a registration sequence disposed therein for identification of the number or relative position of determined sequence from the template sequence. Particularly preferred aspects include a registration sequence in a circular template nucleic acid sequence which is, in turn, used in sequence by incorporation processes that rely upon template dependent, polymerase mediated primer extension in the identification of the sequence of the template.2011-09-01
20110212437SINGLE MOLECULE SEQUENCING WITH TWO DISTINCT CHEMISTRY STEPS - Methods, Compositions, and Systems are provided for nucleic acid sequencing where the sequential incorporation of nucleotides uses two distinct chemical steps. A plurality of nucleotide analogs, each having a labeled leaving group at its 3′ hydroxyl can be sequentially added to a growing strand in the presence of a selective cleaving activity that cleaves the 3′ hydroxyl leaving group preferentially after it has been incorporated. The selective cleaving agent can comprise an exonuclease activity, and the exonuclease activity can be a polymerase-associated exonuclease activity. Nucleotide analogs having labels on both a cleavable polyphosphate portion and on a 3′ hydroxyl leaving group can provide signals characteristic of nucleotide analog incorporation. Systems having illumination optics, collection optics, and substrates observe signals from the labels as they are being incorporated into a growing nucleic acid strand, allowing for the sequencing of template nucleic acids.2011-09-01
20110212438Kits and Devices for Performing Methods of Detecting Viability-Associated Molecules - Kits and devices for performing a method of detecting a molecule associated with viability of one or more cells or organisms in a sample are provided. The method comprises the initial step of contacting the sample with an enzyme, which enzyme is capable of adding or removing a chemical moiety to or from a nucleic acid molecule in the presence of the molecule associated with viability of the one or more cells or organisms. This thereby generates a novel detectable nucleic acid molecule. The next step involves detecting the presence of the molecule associated with viability of the one or more cells or organisms by detecting the novel nucleic acid molecule generated only in the presence of the molecule associated with viability of the one or more cells or organisms. A most preferred molecule associated with viability is ATP, although NAD may also be detected. A preferred enzyme for use in the methods is ligase. The kits and devices for performing the method have numerous applications, in particular in monitoring viability of cells, toxicology testing and determining whether there is contamination in a sample or on a surface.2011-09-01
20110212439HLA ALLELES ASSOCIATED WITH ADVERSE DRUG REACTIONS AND METHODS FOR DETECTING SUCH - This invention relates to a method of determining the presence of certain HLA alleles, such as HLA-B*1502 or HLA-B*5801, and a kit for carrying out this method. Also disclosed is a method for assessing whether a patient is at risk for developing adverse drug reactions (e.g., Stevens-Johnson syndrome, toxic epidermal necrolysis, or hypersensitivity syndrome) based on the presence or absence of a genetic marker (e.g., HLA-B*1502, HLA-B*5801, or HLA-B*4601).2011-09-01
20110212440CELL SORTING DEVICE - An integrated microsystem, comprising: a microchannel, a field generator to create a magnetic field in at least one first portion of the microchannel having a direction substantially collinear with the direction of flow in the portion of the microchannel, the magnetic field also presenting a gradient, wherein the microsystem additionally comprises a detection area in fluid connection with the microchannel,2011-09-01
20110212441Methods and Systems for Inferring Bovine Traits - Methods, compositions, and systems are provided for managing bovine subjects in order to maximize their individual potential performance and edible meat value, and to maximize profits obtained in marketing the bovine subjects. The methods and systems draw an inference of a trait of a bovine subject by determining the nucleotide occurrence of at least one bovine SNP that is identified herein as being associated with the trait. The inference is used in methods of the present invention to establish the economic value of a bovine subject, to improve profits related to selling beef from a bovine subject; to manage bovine subjects, to sort bovine subjects; to improve the genetics of a bovine population by selecting and breeding of bovine subjects, to clone a bovine subject with a specific trait, to track meat or another commercial product of a bovine subject; and to diagnose a health condition of a bovine subject. Methods are also disclosed for identifying additional SNPs associated with a trait, by using the associated SNPs identified herein.2011-09-01
20110212442UNIVERSAL NUCLEIC ACID PROBE SET AND METHOD FOR UTILIZATION THEREOF - A nucleic acid probe set includes (A) a fluorescent probe and (B) a binding probe. The fluorescent probe (A) is formed of an oligonucleotide, which includes (a) a nucleotide unit labeled with (d) a fluorescent substance. The binding probe (B) is formed of an oligonucleotide having (b2011-09-01
20110212443Method for determining the specific growth rate of distinct microbial populations in a non-homogeneous system - The present invention pertains to a molecular biology-based method and kit for measuring the specific growth rate (or cell doubling time) of distinct microbial populations. The method and kit can be used to analyze mixed culture samples that have been exposed to chloramphenicol or other protein synthesis inhibitors for defined times. In a preferred embodiment, the method of the invention (also referred to herein as FISH-RiboSyn) is an in situ method that utilizes fluorescence in situ hybridization (FISH) with probes that target: (1) the 5′ or 3′ end of precursor 16S rRNA; or (2) the interior region of both precursor 16S rRNA and mature 16S rRNA. Images can be captured for a defined exposure time and the average fluorescent intensity for individual cells can be determined. The rate of increase of the whole cell fluorescent intensity is used to determine the specific growth rate. The method of the invention can be attractive for rapidly measuring the specific growth rate (or cell doubling time) of distinct microbial populations within a mixed culture in industries such as environmental systems (water and wastewater treatment systems), bioremediation (optimization of conditions for microbial growth), public health (identification of rapidly growing infectious microbes), and homeland security (identification of rapidly growing bioterrorism agents).2011-09-01
20110212444USE OF METHYLATION STATUS OF MINT LOCI AND TUMOR RELATED GENES AS A MARKER FOR MELANOMA AND BREAST CANCER - The invention relates to a method of detecting melanoma or breast cancer using DNA methylation in MINT17, MINT31, or the promoter region of WIF1, TFPI2, RASSF1A, SOCS1, GATA4, or RARβ2 as a biomarker. Also disclosed are methods of using the biomarker for determining the cancer status and predicting the outcome of the cancer.2011-09-01
20110212445SWI5 GENE AS A DIAGNOSTIC TARGET FOR THE IDENTIFICATION OF FUNGAL AND YEAST SPECIES - The invention relates to the SWI5 gene, the corresponding RNA, specific probes, primers and oligonucleotides related thereto and their use in diagnostic assays to detect and/or discriminate between fungal and yeast species.2011-09-01
20110212446FAST PCR FOR STR GENOTYPING - Disclosed is a method of amplifying a nucleic acid sequence, wherein the method comprises subjecting a reaction mixture to at least one amplification cycle, wherein the reaction mixture comprises a double-stranded nucleic acid and at least two primers capable of annealing to complementary strands of the double-stranded nucleic acid and amplifying at least one short tandem repeat (STR) using a Family A DNA polymerase in a Fast PCR protocol having a two-step amplification cycle in 25 seconds or less. Also disclosed are real-time PCR methods using the two-step protocol and kits for STR profiling using the Fast PCR protocol.2011-09-01
20110212447Method of Using FOXO3A Polymorphisms and Haplotypes to Predict and Promote Healthy Aging and Longevity - The invention provides methods and compositions relating to identification and use of genetic information from the FOXO3A gene that can be used for determining and increasing an individual's likelihood of longevity and of retaining physical and cognitive function during aging, and for determining and decreasing an individual's likelihood of developing a cardiovascular-, metabolic- or age-related disease, including coronary artery (heart) disease, stroke, cancer, chronic pulmonary disease, diabetes, Parkinson's disease and dementia.2011-09-01
20110212448GAMMACARBOXYGLUTAMATE-RICH PROTEIN, METHODS AND ASSAYS FOR ITS DETECTION, PURIFICATION AND QUANTIFICATION AND USES THEREOF - The presently disclosed subject matter refers to a gammacarboxyglutamate-rich protein that shows in vivo a high capacity to bind calcium through specific gamma carboxylated glutamic acid residues (Gla). It includes a description of the referred protein, purification procedures, protein detection and quantification tools and methods. A kit for the detection and quantification of said protein in samples is contemplated. This kit can include the use of one or more antibodies produced against the homologous sequence of the target species to be analyzed, and thus, methods for the production of such antibodies are disclosed as well. In another aspect, the methods and tools described hereby can be used as biomarkers for evaluation of presence or risk to develop certain diseases. In another aspect of the disclosed subject matter, available complete GRP cDNA and gene sequences obtained from several species also enable the in vitro production of antigens, the quantification of GRP expression, the screening of GRP polymorphisms to access the predisposition for certain diseases and the screening for GRP mutations.2011-09-01
20110212449DISTINGUISHING PCA3 MESSENGER RNA SPECIES IN BENIGN AND MALIGNANT PROSTATE TISSUES - This invention concerns the discovery of two distinct PCA3 mRNA sequences. One of these sequences corresponds to a short PCA3 mRNA molecule whereas the other PCA3 RNA molecule is longer as it comprises an additional sequence between exon 3 and exon 4a. The short RNA is associated with prostate cancer whereas the long RNA sequence is associated with a non-malignant state of the prostate. Based on the differential expression levels of these two PCA3 RNA sequences, protocols for the diagnosis of prostate disease are provided. The invention also relates to therapeutic approaches to prostate cancer.2011-09-01
20110212450Polarization-enhanced detector with gold nanorods for detecting nanoscale rotational motion and method therefor - A nanoscale motion detector attaches a gold nanorod (2011-09-01
20110212451RNA DETECTION METHOD - The present invention relates to methods for the detection of target RNA sequences and to RNA amplification methods making use of strand displacement techniques employing RNA-dependent RNA polymerases having RNA-oligonucleotide duplex separation activity and being capable of de novo RNA synthesis in the absence of a primer. The present invention further relates to kits for carrying out such methods.2011-09-01
20110212452METHOD FOR PREPARATIVE PRODUCTION OF LONG NUCLEIC ACIDS BY PCR - The invention relates to a method for preparative production of long nucleic acids by PCR. The method involves the following hybridization steps: a) a nucleic acid base sequence is hybridized on the 3′ and 5′ ends with an adapter primer; b) the product from step a) is hybridized on the 3′ and 5′ ends with an extension primer containing an extension sequence, wherein a nucleic acid with extension sequences amplified and enlarged in the 3′ and 5′ ends of the nucleic acid base sequence is then formed from the nucleic acid base sequence. The invention also relates to different applications of the inventive method.2011-09-01
20110212453ASSAY CARD FOR SAMPLE ACQUISITION, TREATMENT AND REACTION - The present disclosure relates to devices and systems and methods for their use for detecting an analyte. In particular, the present disclosure provides a disposable assay card in which reaction reagents are stored within the card to facilitate point-of-care application.2011-09-01
20110212454Assay for Telomerase Activity - The invention is directed to methods for determining the level of telomerasc reverse transcriptase activity in mammalian cells.2011-09-01
20110212455METHOD OF SCREENING MATERIAL FOR IMPROVING SKIN FUNCTIONS - A method of screening a material for improving skin functions includes: (a) treating a skin cell with a candidate material; (b) detecting a change in a relative expression level of membrane-associated protein 17 (MAP17) gene; and (c) selecting a candidate material inducing the change in the expression level of the gene as a material for improving skin functions.2011-09-01
20110212456K-ras and B-raf mutations and anti-EGFr antibody therapy - The present application relates to K-ras mutations, to polynucleotides encoding mutant K-ras polypeptides, and to methods of identifying K-ras mutations. The present application also relates to B-raf mutations, to polynucleotides encoding mutant B-raf polypeptides, to vectors containing those polynucleotides, and to methods of identifying B-raf mutations. The present application also relates to methods of diagnosing cancer; and methods and kits for predicting the usefulness of anti-EGFr specific binding agents in the treatment of tumors.2011-09-01
20110212457Methods and compositions for determining the pathogenic status of infectious agents - The present invention relates to methods and compositions for improved detection of infectious agents and microbes. In particular, the present invention provides novel methods for detecting infectious agents, providing information about the viability status of such infectious agents and for determining drug susceptibility. In certain embodiments, the present invention employs techniques involving nucleic acid amplification-based microbial identification together with phage-based biological detection of drug resistance. The methods of the invention are suitable for all microbes and infectious agents, including bacterial agents such as Mycobacteria.2011-09-01
20110212458Methods for Production of Xylitol in Microorganisms - The invention provides biosynthetic routes to xylitol production that do not require pure 2011-09-01
20110212459NOVEL PRESENILIN ASSOCIATED MEMBRANE PROTEIN (PAMP) AND USES THEREOF - Presenilin Associated Membrane Protein (PAMP), and nucleic acids encoding this protein, are provided. PAMP and PAMP nucleic acids provide diagnostic and therapeutic tools for evaluating and treating or preventing neurodegenerative diseases. In a specific embodiment, mutations in PAMP are diagnostic for Alzheimer's Disease or spina bifida. The invention further relates to screening, particularly using high-throughput screens and transgenic animal models, for compounds that modulate the activity of PAMP and presenilins. Such compounds, or gene therapy with PAMP, can be used in treating neurodegenerative diseases, particularly Alzheimer's Disease. In addition, the invention provides PAMP mutants, nucleic acids encoding for PAMP mutants, and transgenic animals expressing PAMP mutants, which in a preferred aspect result in biochemical changes similar to those induced by mutations in KNAPP, PS1, or PS2, associated with familial Alzheimer's disease.2011-09-01
20110212460ASSAY FOR NITROUS OXIDE NEUROLOGIC SYNDROME - A method for detection of susceptibility to nitrous oxide neurologic syndrome in a subject is disclosed. In one embodiment, the method comprises: (a) providing a sample from a subject, wherein said subject is a candidate for nitrous oxide anesthesia; and (b) detecting the presence or absence of folate, cobalamin, methionine and homocysteine pathway genetic polymorphisms in said sample, wherein the presence of a polymorphism indicates that the subject is susceptible to nitrous oxide neurologic syndrome.2011-09-01
20110212461PREDICTION OF CARDIOTOXICITY - The likelihood that a compound will exhibit cardiotoxicity in an in vitro or in vivo assay predicted by the ability of the compound to inhibit at least one kinase from a selected group.2011-09-01
20110212462ULTRA-SENSITIVE DETECTION OF MOLECULES USING DUAL DETECTION METHODS - Described herein are systems and methods for the detection of and/or determination of a measure of the concentration of analyte molecules or particles in a fluid sample. In some cases, the systems and methods employ techniques to reduce or limit the negative effects associated with non-specific binding events. Certain methods of the present invention involve associating the analyte molecules at least a first type of binding ligand and at least a second type of binding ligand, and spatially segregating the analyte molecules into a plurality of locations on a surface. The presence of an analyte molecule at or in a location may be determined by determining the presence of both the first type of binding ligand and the second type of binding ligand.2011-09-01
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