34th week of 2011 patent applcation highlights part 50 |
Patent application number | Title | Published |
20110207930 | IMPROVED PRODUCTION METHOD FOR ADEFOVIR DIPIVOXIL - The present invention relates to an improved method of preparing adefovir dipivoxil of Formula 1. The method of the present invention is characterized by using dimethylsulfoxide as a reaction solvent, and comprises a process of preparing adefovir dipivoxil of Formula 1 by allowing adefovir of Formula 2 to react with chloromethylpivalate at a reaction temperature of 30 to 50° C. under the presence of dimethylsulfoxide and triethylamine solvents. | 2011-08-25 |
20110207931 | PREPARATION OF VALGANCICLOVIR AND ITS SALTS - The application relates to processes for preparing valganciclovir and pharmaceutically acceptable salts thereof, as well as intermediates for the processes. valganciclovir hydrochloride is represented by Formula II. | 2011-08-25 |
20110207932 | Process for preparing aminocrotonylamino-substituted quinazoline derivatives - The invention relates to an improved process for preparing aminocrotonylamino-substituted quinazoline derivatives of general formula (I) | 2011-08-25 |
20110207933 | PROCESS FOR THE PREPARATION OF ZIPRASIDONE - The invention relates to processes for the preparation of substantially pure ziprasidone. The invention also relates to the preparation of acid addition salts of ziprasidone. More particularly, it relates to the preparation of substantially pure hydrochloride salt of ziprasidone. The invention also relates to pharmaceutical compositions that include the substantially pure ziprasidone or ziprasidone hydrochloride and use of said compositions for treating schizophrenia. | 2011-08-25 |
20110207934 | PYRIDINE BORANE COMPLEXES - The present invention relates to new borane complexes with substituted pyridines, a process for the synthesis of new borane complexes with substituted pyridines, solutions comprising new borane complexes with substituted pyridines and a method of using new borane complexes with substituted pyridines for organic reactions. | 2011-08-25 |
20110207935 | FUSED-RING DERIVATIVE AND MEDICAL APPLICATION OF SAME - The present invention provides compounds useful as agents for the prevention or treatment of a disease associated with abnormal plasma uric acid level and the like. The present invention relates to fused ring derivatives represented by the following formula (I) having xanthine oxidase inhibitory activities and useful as agents for the prevention or treatment of a disease associated with abnormality of plasma uric acid level, prodrugs thereof, salts thereof or the like. In the formula (I), X | 2011-08-25 |
20110207936 | METHOD FOR PRODUCING OXADIAZOLINONE COMPOUND AND INTERMEDIATE THEREOF - A compound represented by the formula (1): | 2011-08-25 |
20110207937 | Compounds that inhibit (block) bitter taste in composition and methods of making same - The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds present in, e.g., coffee. Also, the invention relates to the discovery of specific compounds and compositions containing that function as bitter taste blockers and the use thereof as bitter taste blockers or flavor modulators in, e.g., coffee and coffee flavored foods, beverages and medicaments. Also, the present invention relates to the discovery of a compound that antagonizes numerous different human T2Rs and the use thereof in assays and as a bitter taste blocker in compositions for ingestion by humans and animals. | 2011-08-25 |
20110207938 | Process for the Preparation of Rufinamide - The present invention relates to a process for the preparation of rufinamide of formula I, which process comprises: (i) reacting a 2,6-difluorobenzylhalide of formula II, wherein X is chloride, bromide or iodide, with an azide to obtain 2-(azidomethyl)-1,3-difluorobenzene of formula III; (ii) reacting 2-(azidomethyl)-1,3-difluorobenzene of formula III with methyl propiolate to obtain methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylic acid of formula IV; and (iii) reacting methyl 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxylic acid of formula IV with ammonia to obtain rufinamide of formula I. | 2011-08-25 |
20110207939 | FACTOR VIIA INHIBITOR - The present invention relates to novel inhibitors of Factors VIIa, IXa, Xa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or preventing thromboembolic disorders, cancer or rheumatoid arthritis. Processes for preparing these inhibitors are also disclosed. | 2011-08-25 |
20110207940 | Preparing 5-fluoro-1-alkyl-3-fluoroalkyl-1H-pyrazole-4-carbonyl chlorides - The present invention relates to a novel process for preparing 5-fluoro-1-alkyl-3-fluoroalkyl-1H-pyrazole-4-carbonyl chlorides, a useful intermediate in the manufacture of fungicides. | 2011-08-25 |
20110207941 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF - The invention relates in a first embodiment to a method for the manufacture of esters of the formula I, | 2011-08-25 |
20110207942 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF TRANS-5-CHLORO-2-METHYL-2,3,3a,12b-TETRAHYDRO-1H-DIBENZ[2,3:6,7]-OXEPINO[- 4,5-c]PYRROLE - Disclosed are novel amino acid derivatives of formula (I) and (II) | 2011-08-25 |
20110207943 | NOVEL PROCESS FOR THE PREPARATION OF ELETRIPTAN - The present invention relates to a novel process for the preparation of (R)-3-((1-methylpyrrolidin-2-yl)methyl)-5-(2-(phenylsulfonyl)ethyl)-1H-indole and its intermediates thereof. | 2011-08-25 |
20110207944 | VITAMIN D3 LACTAM DERIVATIVE - Compound represented by formula (1) or a pharmaceutically acceptable solvate thereof, useful for treating or preventing Paget's disease of bone, hypercalcaemia, osteoporosis or asthma. (1) R | 2011-08-25 |
20110207945 | Process for the preparation of enantiomerically pure 1-substituted-3-aminoalcohols - Provided is a process for the preparation of enantiomerically pure 1-substituted-3-aminoalcohols, particularly of (S)-(−)- and (R)-(+)-3-N-methylamino-1-(2-thienyl)-1-propanol, by asymmetrically hydrogenating salts of a carboxylic acids with an aminoketone of formula (II), wherein R | 2011-08-25 |
20110207946 | Process for the preparation of enantiomerically pure 1-substituted-3-aminoalcohols - Provided is a process for the preparation of enantiomerically pure 1-substituted-3-aminoalcohols, particularly of (S)-(−)- and (R)-(+)-3-N-methylamino-1-(2-thienyl)-1-propanol, by asymmetrically hydrogenating salts of a carboxylic acids with an aminoketone of formula (II), wherein R | 2011-08-25 |
20110207947 | METHOD FOR OBTAINING ZARAGOZIC ACID AND DERIVATIVES THEREOF - The present invention is aimed at a process for obtaining zaragozic acid and derivatives thereof, to the intermediate compounds of this synthesis and to the use of these intermediate compounds in the preparation of zaragozic acid. | 2011-08-25 |
20110207948 | PROCESS FOR PREPARING NEBIVOLOL - The present invention relates to a process for preparing Nebivolol and, more particularly, to an improved method of debenzylation of a compound of formula (II) useful for preparing nebivolol endowed with high purity. | 2011-08-25 |
20110207949 | PROCESS FOR THE PREPARATION OF RAMELTEON - Disclosed herein is a process for resolving N-[2-(1,6,7,8-tetrahydro-2H-indeno [5,4-b] furan-8-yl)] ethylamine into its isomers using an optically active acid and a process for preparing ramelteon from the resolved isomer. | 2011-08-25 |
20110207950 | VINYL-CONTAINING COMPOUNDS AND PROCESSES FOR MAKING THE SAME - The present invention provides a process for forming vinyl-containing compounds including the steps of: a) reacting in a nitrogen atmosphere a dicarboxylic acid and/or anhydride and a functional mono or polyfunctional alcohol to provide a hydroxyl-containing polyester; b) reacting the hydroxyl-containing polyester with a vinyl-containing organic acid in the presence of an esterification catalyst, a polymerization inhibitor and an azeotropic agent; and c) reacting the vinyl functional esterified intermediate, residual esterification catalyst and residual vinyl-containing organic acid with an epoxy to provide the vinyl-containing compound. | 2011-08-25 |
20110207951 | 7-Iodo Tetracyclines and Related Methods - 7-substituted fused ring tetracycline compounds, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7-substituted fused ring tetracycline compounds are described. | 2011-08-25 |
20110207952 | CHOLESTEROL EXTRACTION FROM ALGAE AND PREPARATION OF VEGAN VITAMIN D3 - A process for producing vegan vitamin D3 from an algal waste processing stream by saponifying the waste stream to separate out and removing unsaponifiable cholesterol and converting it to vitamin D3 by ultraviolet irradiation, while precipitating out the saponified fatty acids, triglycerides and polysaccharides. | 2011-08-25 |
20110207953 | REFINED EDIBLE OIL HAVING HIGH BENEFICIAL CONSTITUENTS AND METHODS FOR REFINING THEREOF - Methods for producing refined rice bran oil that include caustic treatment step(s) in an amount that is less than or equal to a theoretical amount of caustic required to neutralize practically all of the free fatty acids in the rice bran oil, but avoiding addition of excess caustic. An objective is to retain a high level of oryzanol in the refined oil. | 2011-08-25 |
20110207954 | Method for Producing Alkoxycarbonylfluoroalkanesulfonic Acid Salt - In the present invention, a target alkoxycarbonylfluoroalkanesulfonic acid salt is obtained by using a halofluoroalkanoic acid ester as a starting raw material, sulfinating the halofluoroalkanoic acid ester in the presence of an amine (as a first step), and then, oxidizing the resulting sulfination product (as a second step). Further, an alkoxycarbonylfluoroalkanesulfinic acid onium salt, which is useful as a photoacid generator, is obtained by salt exchange reaction of the alkoxycarbonylfluoroalkanesulfonic acid salt. | 2011-08-25 |
20110207955 | Process for the production of organic dithiopyrophosphates - Organic dithiopyrophosphates of formula wherein R | 2011-08-25 |
20110207956 | INTRAMOLECULAR C-H AMINATION WITH PHOSPHORYL AZIDES - A highly effective Co(II)-based system has been developed for catalytic intramolecular C—H amination with phosphoryl azides without the need of terminal oxidant or other additives, resulting in the high-yielding production of cyclophosphoramidates with nitrogen gas as the by-product; additional features of this new catalytic system include the amination of primary C—H bonds and formation of 7-membered ring structures. | 2011-08-25 |
20110207957 | PROCESSES FOR THE PREPARATION OF BIPHENYL COMPOUNDS - The invention concerns processes for the synthesis of a compound of the formula: wherein: R | 2011-08-25 |
20110207958 | PROCESS FOR THE PREPARATION OF BENZONORGORNENES - The present invention relates to a novel a process for the preparation of 9-dichloromethylene-1,2,3,4-tetrahydro-1,4-methano-naphthalen-5-ylamine which process comprises a) reacting cyclopentadiene in the presence of a radical initiator and CXCI | 2011-08-25 |
20110207959 | HYDROGENATION AND ESTERIFICATION TO FORM DIESTERS - A process is disclosed which employs hydrogenation and esterification to form alkyl diesters. The process subjects an unrefined or otherwise not purified composition comprising maleic anhydride production residue to the processes of hydrogenation and esterification and forming diesters at high conversion efficiency. | 2011-08-25 |
20110207960 | Process For The Preparation Of Iodinated Contrast Agent - The present invention relies on a process for the preparation of non ionic iodinated contrast agents and, in more details, it relates to a process for the preparation of Iopamidol in high yields and with a high degree of purity. In more details, the invention discloses a process for the preparation of a compound of formula (III) comprising the 5 condensation reaction a compound of formula (II) with 2-amino-1,3-propandiol, being said reaction carried out in an aprotic dipolar solvent and in the presence of an alkaline or alkaline rare earth metal oxide or hydroxide. | 2011-08-25 |
20110207961 | PROCESS FOR PREPARING ISOCYANATES - The invention relates to an improved multistage process for the continuous preparation of diisocyanates by reaction of the corresponding diamines with carbonic acid derivatives and alcohols to form low molecular weight monomeric urethanes and thermal dissociation of the latter. | 2011-08-25 |
20110207962 | PRODUCTION METHOD OF METHIONINE - The present invention aims to provide a method of producing methionine by hydrolyzing M-hydantoin in the presence of a basic potassium compound, which can effectively prevent corrosion of reaction vessels in both the liquid phase and gaseous phase of a hydrolysis solution even at a higher temperature, and enables a longer period of stable production of methionine. Provided is a method of producing methionine, comprising hydrolyzing 5-(β-methylmercaptoethyl)hydantoin in water in the presence of a basic potassium compound in a reaction system having a potassium concentration of not more than 9 wt % at a temperature of not less than 170° C. | 2011-08-25 |
20110207963 | PREPARATION OF IODIXANOL - A process for the preparation of iodixanol by dimerisation of 5-acetamido-N,N′-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-isophthalamide (“Compound A”) in which, after the dimerisation step, unreacted Compound A is precipitated from the reaction mixture and recovered for re-use. The process substantially increases the net yield of iodixanol and simplifies its purification. | 2011-08-25 |
20110207964 | PROCESS FOR PRODUCING NITROGEN-CONTAINING COMPOUNDS - The present invention relates to a process for producing a tertiary amine in the presence of a catalyst containing copper and at least one element selected from the group consisting of elements belonging to Groups 2, 3, 7 and 12 of the Periodic Table (long form of the periodic table), said process including the steps of (a) reducing an amide compound in a hydrogen atmosphere; and (b) introducing a dialkyl amine containing a linear or branched alkyl group having 1 to 6 carbon atoms into a reaction product obtained in the step (a), and treating the reaction product with the dialkyl amine. The present invention provides a process for producing high-purity aliphatic tertiary amines containing a less amount of by-products by reducing aliphatic acid amides under moderate conditions using a chromium-free catalyst, as well as a process for producing amine derivatives such as amine oxide by using the aliphatic tertiary amines, with a good productivity in an economical manner. | 2011-08-25 |
20110207965 | PROCESS FOR PREPARING CINACALCET - A process for preparing N-[(1R)-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)-phenyl]propan-1-amine of formula (I) i.e. Cinacalcet and its intermediates of formulae (V), (Va) and (Vb). | 2011-08-25 |
20110207966 | METHOD FOR PRODUCING 6-CHLORODIBENZO[D,F] [1,3,2]-DIOXAPHOSPHEPIN - The invention relates to a method for producing 6-chlorodibenzo[d,f][1,3,2]dioxaphosphepin (formula 1), comprising the following steps: a) addition of 2,2′-dihydroxybiphenyl, which is suspended in an inert solvant. into a reactor to an excess of phosphorous trichloride under inert gas and stirring; b) discharge and neutralization of the resulting gases from the reaction mixture; c) separation of the excess phosphorous trichloride and the solvant; d) obtention of 6-chlorodibenzo[d,f][1,3,2]dioxaphosphepin. | 2011-08-25 |
20110207967 | PROCESS FOR THE PREPARATION OF VITAMIN K2 - Using a combination of Kumada, Suzuki and Biellmann chemistry, various menaquinones can synthesised rapidly and with stereochemical integrity offering a new way of preparing these vitamin K2 components for the pharmaceutical market. In one embodiment a process for the preparation of a compound of formula (I) is defined including a step in which (i) a compound of formula (II) is reacted formula (III) wherein R is an alkyl group; LG is a leaving group; m is an integer from 0 to 8; n is an integer of from 0 to 9; and X is hydrogen, halide, hydroxyl or protected hydroxyl; in the presence of a copper, nickel or palladium catalyst. | 2011-08-25 |
20110207968 | PROCESS FOR PREPARING 4-ISOPROPYLCYCLOHEXYLMETHANOL - The present invention relates to a process for preparing 4-isopropylcyclohexylmethanol (IPCHM) from para-cymene. The process for preparing 4-isopropylcyclohexylmethanol (IPCHM) comprises an electrochemical process for preparing a mixture of 4-isopropylbenzaldehyde dimethyl acetal and 4-(1-alkoxy-1-methylethyl)benzaldehyde dimethyl acetal, and intermediates passed through in the process, a hydrolysis step to form the corresponding benzaldehydes and a hydrogenation of this mixture to form 4-isopropylcyclohexylmethanol (IPCHM). | 2011-08-25 |
20110207969 | PROCESS FOR MAKING POLYOL ETHERS - The present invention generally relates to a process for making polyol ethers by reacting a polyol and a carbonyl compound together in the presence of hydrogen gas and a palladium hydrogenation catalyst on an acidic mesoporous carbon support. | 2011-08-25 |
20110207970 | METHOD OF MAKING CHLOROHYDRINS - Methods and systems for the preparation of chlorohydrins are described herein. The methods and systems incorporate the novel use of a high shear device to promote dispersion and solubility of olefins into the chlorinating phase. The high shear device may allow for lower reaction temperatures and pressures and may also reduce chlorination time. | 2011-08-25 |
20110207971 | PROCESSES AND SYSTEMS FOR THE PRODUCTION OF PROPYLENE GLYCOL FROM GLYCEROL - Processes and systems for converting glycerol to propylene glycol are disclosed. The glycerol feed is diluted with propylene glycol as the primary solvent, rather than water which is typically used. The diluted glycerol feed is sent to a reactor where the glycerol is converted to propylene glycol (as well as other byproducts) in the presence of a catalyst. The propylene glycol-containing product from the reactor is recycled as a solvent for the glycerol feed. | 2011-08-25 |
20110207972 | CATALYSTS AND PROCESSES FOR THE HYDROGENOLYSIS OF GLYCEROL AND OTHER ORGANIC COMPOUNDS FOR PRODUCING POLYOLS AND PROPYLENE GLYCOL - Catalysts for replacing rhenium-containing multimetallic catalysts for the hydrogenolysis of organic compounds to desired polyols, including the conversion of glycerol to propylene glycol, are described. The catalysts are carried on carbon supports, as well as carbon supports impregnated with Zirconium Scandium (ZrSc), Zirconium Yttrium (ZrY), Titanium Scandium (TiSc), or Titanium Yttrium (TiY) to texture the carbon support and to create oxygen-ion vacancies that can be used during the desired reactions. Processes for the hydrogenolysis of organic compounds to desired polyols using the disclosed catalysts, including the conversion of glycerol to propylene glycol, are also described. | 2011-08-25 |
20110207973 | Process for producing allyl alcohol - A process for producing allyl alcohol is disclosed. The process comprises reacting propylene, acetic acid, and oxygen to produce a reaction mixture. The reaction mixture is distilled to produce a vapor stream comprising propylene and a liquid stream comprising allyl acetate, acetic acid, acrolein, and allyl diacetate. The liquid stream is distilled to produce a lights stream comprising acrolein; a side draw comprising allyl acetate, acetic acid, and water; and a bottoms stream comprising acetic acid and allyl diacetate. The bottoms stream is distilled to remove a heavies stream comprising allyl diacetate. The side draw is hydrolyzed to produce allyl alcohol. | 2011-08-25 |
20110207974 | METHOD FOR PRODUCING FLUORINATED ORGANIC COMPOUNDS - Disclosed is a process for producing tetrafluoropropene comprising: (a) catalytically fluorinating at least one tetrafluoropropene in a first reactor to produce HCFO-1233xf; (b) reacting said HCFO-1233xf with hydrogen fluoride in a second reactor to produce HCFC-244bb; (c) recycling at least a portion of said HCFC-244bb back to said first reactor as recycled HCFC-244bb; and (d) catalytically dehydrochlorinating said recycled HCFC-244bb in said first reactor to produce HFO-1234yf. | 2011-08-25 |
20110207975 | INTEGRATED PROCESS TO PRODUCE 2,3,3,3-TETRAFLUOROPROPENE - A method for preparing 2,3,3,3-tetrafluoroprop-1-ene comprising (a) providing a starting composition comprising at least one compound having a structure selected from Formulae I, II and III: | 2011-08-25 |
20110207976 | PROCESS FOR PRODUCING P-DICHLOROBENZENE - To provide a novel process for producing p-dichlorobenzene satisfying both of high selectivity of p-dichlorobenzene and high conversion of chlorine at the same time. | 2011-08-25 |
20110207977 | METHOD FOR PRODUCING A-OLEFIN OLIGOMER, A-OLEFIN OLIGOMER, AND LUBRICATING OIL COMPOSITION - A method of producing an α-olefin oligomer composition of the present invention is a method of producing an α-olefin oligomer composition, the method including the step of causing the molecules of an α-olefin to react with each other with a specific catalyst in the presence of hydrogen. | 2011-08-25 |
20110207978 | Method for starting-up naphtha fraction hydrotreating reactor - A method for starting-up a naphtha fraction hydrotreating reactor which subjects a naphtha fraction obtained in a fractionator by fractional distillation of hydrocarbon compounds produced by a Fischer-Tropsch synthesis reaction to hydrotreating, the method comprising: charging in advance an inactive hydrocarbon compound corresponding to the naphtha fraction into a vapor-liquid separator to which hydrogenated naphtha, which has been subjected to hydrotreating in the naphtha fraction hydrotreating reactor, is transferred; mixing the inactive hydrocarbon compound drawn from the vapor-liquid separator and the naphtha fractions being transferred from the fractionator to the naphtha fraction hydrotreating reactor, and supplying a mixture of the naphtha fractions and the inactive hydrocarbon compound to the naphtha fraction hydrotreating reactor. | 2011-08-25 |
20110207979 | METHOD FOR PRODUCING HIGH VALUE AROMATICS AND OLEFIN FROM LIGHT CYCLE OIL PRODUCED BY A FLUIDIZED CATALYTIC CRACKING PROCESS - The present invention relates to a method of producing aromatic products (benzene/toluene/xylene) and olefin products from petroleum fractions obtained by fluid catalytic cracking, and, more particularly, to a method of producing products comprising high-concentration aromatic products and high value-added light olefin products from light cycle oil obtained by fluid catalytic cracking. | 2011-08-25 |
20110207980 | Method for Production of Styrene from Toluene and Syngas - A method for the production of styrene comprising reacting toluene and syngas in one or more reactors is disclosed. | 2011-08-25 |
20110207981 | ALKYLATION PROCESS USING CATALYSTS WITH LOW OLEFIN SKELETAL ISOMERIZATION ACTIVITY - A process is presented for the production of linear alkylbenzenes. The process includes contacting an aromatic compound with an olefin in the presence of a selective zeolite catalyst. The catalyst includes two zeolites combined to improve the linearity, and to produce detergent grade LAB. The two zeolites are selected to limit skeletal isomerization while producing a desired 2-phenyl content for the LAB. | 2011-08-25 |
20110207982 | PROCESS FOR ETHYLBENZENE PRODUCTION - A method of producing an alkylaromatic by the alkylation of an aromatic with an alkylating agent, such as producing ethylbenzene by an alkylation reaction of benzene, is disclosed. The method includes using an H-beta catalyst in a preliminary alkylation reactor that is located upstream of the primary alkylation reactor. The H-beta catalyst used in a preliminary alkylation reactor can be regenerated and the regenerated H-beta zeolite catalyst can have a deactivation rate that is no more than 120% of the deactivation rate of a fresh H-beta zeolite catalyst. | 2011-08-25 |
20110207983 | Large Crystal Molecular Sieves and Their Manufacture - A process for the manufacture of large crystal size synthetic porous crystalline molecular sieve requires an aqueous reaction mixture that is organic structure directing agent-free, has a H | 2011-08-25 |
20110207984 | ADDITIVE WITH MULTIPLE SYSTEM OF ZEOLITES AND METHOD OF PREPARATION - Additives for mixing with the catalyst inventory in process units for fluid catalytic cracking (FCC) for maximizing the production of LPG and light olefins are described. Said additives comprise a matrix that incorporates a zeolite of type MFI, preferably zeolite ZSM-5, a zeolite of type Y, and a source of phosphorus, in a single particle. Mixing of the additive in proportions from 1.0 to 40 wt. % with the equilibrium catalyst of an FCC unit maximizes the production of LPG and light olefins, chiefly propylene. | 2011-08-25 |
20110207985 | PROMOTERS EXHIBITING ENDOTHELIAL CELL SPECIFICITY AND METHODS OF USING SAME FOR REGULATION OF ANGIOGENESIS - Isolated polynucleotide sequences exhibiting endothelial cell specific promoter activity, novel cis regulatory elements and methods of use thereof enabling treatment of diseases characterized by aberrant neovascularization or cell growth are disclosed. | 2011-08-25 |
20110207986 | SYSTEM AND METHOD FOR RADIATION DOSE REDUCTION IN MOLECULAR BREAST IMAGING - A system and method is provided for analyzing detector data acquired during molecular breast imaging (MBI) that reduces a patient's radiation does without a reduction in image quality. The method processes and combines initial images acquired by the two gamma-camera detectors of the MBI system to produce a hybrid or composite image set having reduced noise and improved contrast. The composite image provides image quality comparable to that of traditional MBI methods, but at a lower patient radiation dose. | 2011-08-25 |
20110207987 | Methods And Devices For Delivering Appropriate Minimally-Invasive Extraocular Radiation - The present invention also features a brachytherapy system comprising a spiral cut tube having a first end and a second end; a radioactive brachytherapy source (RBS) disposed on the first end of the spiral cut tube; and a handle and a generally hollow cannula disposed on the handle, wherein a channel is disposed in the handle aligned with the hollow cannula, and the spiral cut tube and RBS are adapted to slide within the channel and the hollow cannula. | 2011-08-25 |
20110207988 | Method, apparatus and computer program for non-invasive brain stimulation when target muscles are suitably active - The present invention introduces a magnetic stimulation method in which a desired biosignal value or a range of values for at least one target is determined. Upon stimulation, magnetic field pulses of short duration are applied to the brain and the biosignal, such as electromyograph (EMG), value (S) of each target, such as a muscle, is measured before each TMS pulse. The firing of a TMS pulse is automatically prevented if the corresponding measured biosignal value (S) is outside the predetermined limits. | 2011-08-25 |
20110207989 | DEVICES AND METHOD FOR TREATMENT OF DEGENERATIVE JOINT DISEASES WITH ELECTROMAGNETIC FIELDS - Described herein are devices and methods for treating degenerative joint diseases with electromagnetic fields using one or more waveforms that are configured to modulate Ca | 2011-08-25 |
20110207990 | Methods and Apparatus for Aligning Antennas of Low-Powered Intra - and Extra - Oral Electronic Wireless Devices - The present invention relates generally to the design and optimal placement of transmitting and receiving directional antennas, a priori, as used in intra-oral to extra-oral (or visa versa) wireless electronic systems regardless of the type and purpose of the data transmitted between the antennas (intra-oral and extra-oral). Systems related to the invention transmit data via electromagnetic radio waves or through an inductive loop coupling such as in stimulating the human hearing nerve (inner ear) via dental bone conduction pathway when operating in “receive mode”. “Send mode” systems related to the invention transmit non-acoustic information or voice data from inside the mouth to a receiver located outside the mouth. | 2011-08-25 |
20110207991 | METHOD AND APPARATUS FOR PROVIDING THERAPY USING SPONTANEOUS OTOACOUSTIC EMISSION ANALYSIS - A method and apparatus for providing therapy using spontaneous otoacoustic emission (SOAE) analysis is described. In one embodiments, a method for utilizing the voice-ear-brain connection to achieve self-healing includes capturing audio emissions of at least one ear of a patient, determining a frequency spectrum of the audio emissions, identifying a peak frequency in the frequency spectrum, and producing at least one audio signal in response the peak frequency. | 2011-08-25 |
20110207992 | IMPLANTABLE URETHRAL PROSTHESIS HAVING TABLE MEMBER - An implantable urethral prosthesis for the treatment of male incontinence and method of implementing the same includes a support portion, an inflatable member, a reservoir-pump and a restrictor. The support portion includes at least a first set of two arms extending from the support portion, each arm of the first set of two arms configured to be secured around a respective descending rami of a pelvis of a patient, and a second set of two arms extending from the support portion and configured to be secured into tissue anterior to the pelvis to operatively place the support portion under the patient's urethra. The inflatable member is attachable to the support portion and adapted to exert a force on the urethra when inflated with an inflating agent. | 2011-08-25 |
20110207993 | METHOD FOR ARTIFICIAL INSEMINATION OF COWS - The present invention is related to a method of artificial animal reproduction by which healthy cows and heifers are impregnated on the first attempt at artificial insemination. The sperm is deposited at the time the uterine horns are at the optimum time to conceive. | 2011-08-25 |
20110207994 | Methods and Devices for Treating Morbid Obesity Using Hydrogel - An environmentally sensitive hydrogel material swells or collapses in response to a parameter such as pH level associated with consumption of food by a patient. This swelling or collapsing is harnessed to treat morbid obesity or some other condition of the patient. The swelling or collapsing of the hydrogel may be used to tighten a gastric band or gastric valve when the patient starts eating; then loosen the band or valve when the patient is between meals. The swelling or collapsing of the hydrogel may also be used to increase the size of a space occupying device in the patient's stomach when the patient starts eating; then decrease the size of the space occupying device when the patient is between meals. The swelling or collapsing of the hydrogel may also be used to selectively restrict the absorption of nutrients within a patient's gastrointestinal tract, such as in the duodenum. | 2011-08-25 |
20110207995 | INDUCTIVELY POWERED REMOTELY ADJUSTABLE GASTRIC BANDING SYSTEM - A power management system provides wireless power to operate components of a remotely adjustable gastric banding system. The power management system comprises an external power component transmitting power, and an implantable power management component receiving power and converting the power for use in powering one or more components of the remotely adjustable gastric banding system, such as a pump. The internal power management component and the external power component may be tunable. By utilizing the power management system, implantable batteries may be eliminated. | 2011-08-25 |
20110207996 | DEVICES AND METHODS FOR CARDIAC ANNULUS STABILIZATION AND TREATMENT - Devices and methods generally provide enhanced stabilization, exposure and/or treatment of a cardiac valve annulus. Methods generally involve introducing a stabilizing member beneath one or more leaflets of a heart valve to engage the annulus at an intersection between the leaflets and the interior ventricular wall of the heart. Force is then applied to the stabilizing member to stabilize and/or expose the valve annulus. In some embodiments, the stabilizing member may include a series of hydraulically driven tethered anchors, such as hooks or clips, for engaging and cinching valve annulus tissue to decrease the diameter of a regurgitant valve. Alternatively, other treatments may be delivered by a stabilizing member, such as radiofrequency energy, drugs, bulking agents or shape memory stents. A second stabilizing member may also be introduced above the leaflets for further stabilization. | 2011-08-25 |
20110207997 | Locatable Catheter - A catheter having a sensor at a distal end thereof, useable to detect and create signals from an electromagnetic field. The sensor is constructed and arranged to leave a lumen of the catheter open such that it may be used to pass instruments therethrough once a target location has been reached. | 2011-08-25 |
20110207998 | CAPSULE MEDICAL APPARATUS - A capsule medical apparatus capable of injecting a medical agent into a living tissue includes a casing, a pressing member that presses the surface of the living tissue, a driving unit that causes the pressing member to protrude from the casing in a predetermined direction and to press the surface of the living tissue while rotating the pressing member around a rotation axis parallel to the protruding direction, and a needle-like puncturing member that is arranged on the pressing member and punctures the living tissue in an oblique direction with respect to the surface of the living tissue to thereby inject the medical agent into the living tissue along with the rotation of the pressing member driven by the driving unit. | 2011-08-25 |
20110207999 | TORQUE TRANSMISSION DEVICE HAVING CONTROL WIRE - A torque transmission device is a steerable device for an endoscope, and includes a first link element having a first guide lumen. A second link element is disposed at a distal end of the first link element in a longitudinal axis direction, and has a second guide lumen. A control wire is disposed through the first and second guide lumens movably in the longitudinal axis direction. A pivot mechanism couples the first link element to the second link element in a rotatable manner about a pivot axis being perpendicular to the longitudinal axis direction. The control wire through the first and second guide lumens extends in a coplanar manner with the pivot axis and crosswise thereto. Preferably, there is a flexible section having the first and second link elements. A steering unit has third and fourth link elements. | 2011-08-25 |
20110208000 | MEDICAL SYSTEM - A medical system includes: a first operation apparatus used when a first doctor operates a medical instrument; a second operation apparatus that outputs a control instruction signal for controlling a motion of the medical instrument, and is operated by a second doctor; at least one medical action information detection section that detects medical action information based on the motion of the medical instrument when the first doctor operates the medical instrument using the first operation apparatus; a storage apparatus that stores reference information set by the second doctor according to the first doctor for comparing with the medical action information detected by the medical action information detection section; a switching signal generation apparatus that is connected to the second operation apparatus, and switches an output destination of the control instruction signal based on the medical action information detected by the medical action information detection section and the reference information stored in the storage apparatus; and a medical instrument control apparatus that controls the medical instrument according to the control instruction signal of the second operation apparatus outputted from the switching signal generation apparatus. | 2011-08-25 |
20110208001 | ENDOSCOPE - Provided is an endoscope with a handle and an endoscope shaft connected to the handle, which has a bendable section and a rigid section, adjoining it, with a support extending in the longitudinal direction of the endoscope shaft, wherein the bendable section has a flexible outer tube the end of which facing the rigid section rests on the support, wherein a fixing sleeve is connected to the end section and covers the end of the outer tube facing the rigid section such that said end is clamped for fixing between the fixing sleeve and the support. | 2011-08-25 |
20110208002 | ENDOSCOPE APPARATUS - An endoscope apparatus includes a display portion coupled to an operation portion, configured to be moved relative to the operation portion and configured to display an observation image obtained by the endoscope apparatus, a bending operation portion provided at the operation portion and configured to be moved in a basic direction relative to the operation portion wherein the bending operation portion is configured to be moved in an additional direction different from the basic direction, and a movement driving mechanism configured to move the display portion relative to the operation portion according to movement of the bending operation portion in the additional direction relative to the operation portion. | 2011-08-25 |
20110208003 | SUCTION CONDUIT DEVICE OF ENDOSCOPE THAT PREVENTS CLOGGING - In a suction valve in which a suction conduit is connected from a treatment instrument insertion channel through a branch portion so as to open/close this suction conduit, there is no passage between a side face of a valve-portion passage in the valve and a side face of a piston shaft, but only the valve-portion passage and an inner-shaft passage of the piston shaft are used, and their diameters d | 2011-08-25 |
20110208004 | ENDOSCOPIC LED LIGHT SOURCE HAVING A FEEDBACK CONTROL SYSTEM - An external endoscope light source system includes light emitting diodes for providing a light output to an endoscope. The light is provided to a fiber optic cable for transmission to the endoscope. A fiber optic receives a portion of the light output and provides the output to a color sensor for sensing color values. The color values are provided to a controller that adjusts power to the various LEDs to provide a white light output. Instead of a color sensor in the light source, the light source can receive a white balance signal from a video camera provided for an endoscope. The white balance signal varies intensity of light output from each of the LEDs to obtain a white light output. The camera also provides shutter speed of a camera image sensor to the light source. The shutter speed is used to pulse or modulate the light output only when the shutter of the camera is open. By modulating the light output by the light source, the amount of heat generated by the light source is minimized. | 2011-08-25 |
20110208005 | SURGICAL RETRACTOR - A surgical retractor and a method of minimally invasive surgery, wherein the surgical retractor includes ribs and a mechanism for transferring of linear and rotational movements of the ribs and wherein each rib can be easily replaced without use of any additional tools. | 2011-08-25 |
20110208006 | SURGICAL RETRACTOR - A surgical retractor and a method of minimally invasive surgery, wherein the surgical retractor includes ribs and a mechanism for transferring of linear and rotational movements of the ribs and wherein each rib can be easily replaced without use of any additional tools. According to embodiments of the present invention, specific parts composing the surgical retractor are made of materials transparent to Röntgen rays (x-rays). | 2011-08-25 |
20110208007 | Rapid Laparoscopy Exchange System And Method Of Use Thereof - A system for positioning an interchangeable tool in a body cavity that includes a channel having a lumen in direct communication with the body cavity; a tool introducer having a longitudinal axis and a distal end and wherein the tool introducer is capable of traveling through the channel lumen; and a tool holder covering at least a portion of the interchangeable tool wherein the tool holder is pivotally connected to the tool introducer distal end, thereby allowing angular positioning of the interchangeable tool after the tool holder emerges from the channel into the body cavity. A method for engaging an interchangeable tool with a distal portion of a tool manipulator in a body cavity that includes inserting a tool introducer into a channel, the channel having a lumen providing direct communication into the body cavity and wherein a proximal end of the interchangeable tool is reversibly connected to a distal end of the tool introducer; orienting the distal portion of the tool manipulator in the body cavity; emerging the interchangeable tool from the channel into the body cavity; and positioning the interchangeable tool eccentrically to the lumen of the channel wherein the inner passage of the interchangeable tool is angled towards the distal portion of the tool manipulator. | 2011-08-25 |
20110208008 | SURGICAL RETRACTOR - A surgical retractor and a method of minimally invasive surgery, wherein the surgical retractor includes ribs and a mechanism for transferring of linear and rotational movements of the ribs and wherein each rib can be easily replaced without use of any additional tools. According to embodiments of the present invention, specific parts composing the surgical retractor are made of materials transparent to Röntgen rays (x-rays). | 2011-08-25 |
20110208009 | Physiological signal quality classification for ambulatory monitoring - Physiological signal quality classification methods and systems designed to improve ambulatory monitoring. Physiological signals are classified as good, noisy or weak based on signal properties. Once classified, signals are processed differently depending on their classification in order to encourage reliance on reliable physiological data, discourage reliance on unreliable physiological data and induce action to improve signal quality. For example, for a good signal, physiological data may be extracted from the signal and displayed to a person being monitored. For a noisy signal, a noisy signal notification may be displayed to the person in lieu of extracted physiological data. For a weak signal, a weak signal notification may be displayed to the person in lieu of extracted physiological data. Moreover, a noisy or weak signal notification displayed to a person being monitored may be accompanied by a corrective action recommendation, such as “move to quieter environment” for a noisy signal or “check body placement of sensor” for a weak signal. | 2011-08-25 |
20110208010 | MOTION ENERGY HARVESTING WITH WIRELESS SENSORS - A system and method for generating power when one or more motion sensitive structures are moved. The system may include one or more sensing components which, acting alone or in combination, are capable of generating data related to one or more physiological parameters. The system may also include wireless communication circuitry capable of wirelessly transmitting the data related to the one or more physiological parameters. Furthermore, at least one of the one or more sensing components or the wireless communication circuitry may be at least partially powered, directly or indirectly, by the one or more motion sensitive structures. | 2011-08-25 |
20110208011 | SYSTEM AND METHOD FOR GUIDING OF GASTROINTESTINAL DEVICE THROUGH THE GASTROINTESTINAL TRACT - Systems and methods for guidance of a gastrointestinal device through a gastrointestinal tract are provided. A gastrointestinal guidewire is positioned through the gastrointestinal tract, by introduction of an introducing element into the gastrointestinal tract. One end of the gastrointestinal guidewire is attached to the introducing element, and the other end of the gastrointestinal guidewire is attached to an anchoring element, anchored to a location outside of the gastrointestinal tract. Movement of the introducing element through the gastrointestinal tract results in positioning of the guidewire through the gastrointestinal tract. The guidewire is then used as a scaffold to guide the gastrointestinal device, wherein the gastrointestinal device may be externally controlled. This allows for speeding up, slowing down, reversal and stopping of the gastrointestinal device during its descent through the gastrointestinal tract. | 2011-08-25 |
20110208012 | THERAPY PROGRAM MODIFICATION BASED ON A THERAPY FIELD MODEL - Techniques for modeling therapy fields for therapy delivered by medical devices are described. Each therapy field model is based on a set of therapy parameters and represents where therapy will propagate from the therapy system delivering therapy according to the set of therapy parameters. Therapy field models may be useful in guiding the modification of therapy parameters. As one example, a processor compares an algorithmic model of a therapy field to a reference therapy field and adjusts at least one therapy parameter based on the comparison. As another example, a processor adjusts at least one therapy parameter to increase an operating efficiency of the therapy system while substantially maintaining the modeled therapy field. | 2011-08-25 |
20110208013 | Body Parameter Sensor and Monitor Interface - A system for sensing a physiological parameter in a human or animal, and storing a processed sensing signal at a sensor with which the sensing was performed. The system includes a physiological sensor adapted to output a sensor signal representative of a sensed physiological parameter, for processing by a remote processor. A microcontroller has memory, and is located locally to the sensor and is fixedly attached to or housed together with the sensor. An authentication algorithm is stored in the memory and the microprocessor is configured to engage in an authentication process to authenticate the sensor when queried by a remote processor. The memory is configured to receive and store data representative of a sensed physiological parameter after data from the sensor has been processed by a remote processor. The microcontroller may be configured to communicate with a remote processor over a single wire by, for example, using a single wire protocol. | 2011-08-25 |
20110208014 | Determination of extent of congruity between observation of authoring user and observation of receiving user - A computationally implemented method includes, but is not limited to: acquiring a result of an observation of an authoring user; acquiring a result of an observation of a receiving user; comparing the result of the observation of the authoring user with the result of the observation of the receiving user; and presenting data indicative of an extent of congruity between the result of the observation of the authoring user and the result of the observation of the receiving user based at least in part on said comparing. In addition to the foregoing, other related method/system aspects are described in the claims, drawings, and text forming a part of the present disclosure. | 2011-08-25 |
20110208015 | WIRELESS PATIENT MONITORING SYSTEM - A device for obtaining physiological information of a medical patient can include a blood pressure device that can be coupled to a medical patient and a wireless transceiver electrically coupled with the blood pressure device. The wireless transceiver can wirelessly transmit blood pressure data received by the blood pressure device and physiological data received from one or more physiological sensors coupled to the blood pressure device. | 2011-08-25 |
20110208016 | DEVICE FOR QUANTIFICATION AND MONITORING OF CARDIOVASCULAR FUNCTION DURING INDUCED STRESS OR PHYSICAL ACTIVITY AND AT REST - Method and device for the quantification and monitoring of cardiovascular function comprising continuous determination of significant individual cardiovascular function parameters through a multisensory, operator-independent platform during a sample period at rest, recording the data determined, continuously monitoring these data during pharmacological stress or exercise activity, comparing the memorized data with those determined during the same time span of the sample period and comparing the changes in cardiovascular function occurring during stress or exercise vs rest, and comparing the changes in cardiovascular function occurring during recovery vs rest and vs stress or exercise. | 2011-08-25 |
20110208017 | System and method of aquiring blood-vessel data - A system and method is provided for substantially synchronizing the acquisition of blood-vessel data to an identifiable portion of heartbeat data. Specifically, a data-gathering device is adapted to acquire heartbeat data and blood-vessel data from a heart-monitoring device and a data-gathering probe, respectively. In a preferred embodiment of the present invention, the blood-vessel data is acquired during a cyclical portion of the heartbeat data. By identifying a cyclical (or commonly reoccurring) portion of the heartbeat data and acquiring blood-vessel data during this cyclical portion (or during an interval that substantially corresponds thereto), the blood vessel can be analyzed as if it were standing still—i.e., not expanding and relaxing. In one embodiment of the present invention, the heart-monitoring device includes an EKG device, the data-gathering device includes an intra-vascular ultrasound (IVUS) device and a computing device, and the data-gathering probe includes at least one transducer. In another embodiment of the present invention, the data-gathering system further includes a retraction device adapted to move the data-gathering probe though a blood vessel at a substantially steady speed. | 2011-08-25 |
20110208018 | SEPSIS MONITOR - Sensors are attached to a living being so as to generate corresponding sensor signals. A monitor is in communications with the sensors so as to derive physiological parameters responsive to the sensor signals. Predetermined limits are applied to the physiological parameters. At least one indicator responsive to the physiological parameters and the predetermined limits signal the onset of a sepsis condition in the living being. | 2011-08-25 |
20110208019 | WIRELESS-TYPE SUBJECT IN-VIVO INFORMATION ACQUIRING APPARATUS - Provided is a wireless-type subject in-vivo information acquiring apparatus that is introduced into a body cavity of an individual to be examined and acquires subject in-vivo information, and that includes a transmission antenna that has an antenna orientation direction in which a transmission signal that transmits acquired subject in-vivo information is emitted most strongly, and another antenna that has an antenna directivity in a predetermined direction that is different from that of the transmission antenna. The transmission antenna and the other antenna are arranged so that a relationship between the antenna orientation direction of the transmission antenna and the antenna orientation direction of the other antenna is a twisted positional relationship or an intersecting relationship. | 2011-08-25 |
20110208020 | System with a reservoir for perfusion management - A system for perfusion management that monitors, maintains, diagnoses, or treats perfusion deficiencies. | 2011-08-25 |
20110208021 | Systems, devices, and methods including implantable devices with anti-microbial properties - Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant. | 2011-08-25 |
20110208022 | DEVICE AND METHODS FOR SAMPLING PROSTATE FLUID - Disclosed are devices and methods to improve sampling of prostate secretions for purposes of diagnoses, staging, assessment of malignant potential, prognosis. | 2011-08-25 |
20110208023 | Systems, devices, and methods including implantable devices with anti-microbial properties - Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant. | 2011-08-25 |
20110208024 | SYSTEM AND METHOD OF RESOLVING OUTLIERS IN NIRS CEREBRAL OXIMETRY - A system and method for non-invasively estimating the tissue blood oxygen saturation level of a human subject, including so-called “outliers”, whose physiological make-up causes previously-known techniques to generate invalid tissue blood oxygen saturation estimations. The system includes a computing device and a sensor. The sensor includes a light source configured to emit light of at least four different wavelengths, one at a time. The sensor also includes two light detectors, each positioned a different distances from the light source. Optical density measurements are taken by the light detectors and provided to the computing device. A first tissue blood oxygen saturation value is computed using the optical density measurements associated with three of the four wavelengths, and a second tissue blood oxygen saturation value is computed using the optical density measurements associated with four of the wavelengths. The first and second tissue blood oxygen saturation values are compared, and the human subject is identified as an “outlier” based upon that comparison. | 2011-08-25 |
20110208025 | CYANOTIC INFANT SENSOR - A pulse oximetry sensor comprises emitters configured to transmit light having a plurality of wavelengths into a fleshy medium. A detector is responsive to the emitted light after absorption by constituents of pulsatile blood flowing within the medium so as to generate intensity signals. A sensor head has a light absorbing surface adapted to be disposed proximate the medium. The emitters and the detector are disposed proximate the sensor head. A detector window is defined by the sensor head and configured so as to limit the field-of-view of the detector. | 2011-08-25 |
20110208026 | Systems, devices, and methods including implantable devices with anti-microbial properties - Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant. | 2011-08-25 |
20110208027 | Methods And Systems For Providing Therapeutic Guidelines To A Person Having Diabetes - A method is disclosed for providing therapeutic guidelines to a person having diabetes. The method comprises measuring a blood glucose (bG) level of the person for two or more days, wherein at least one bG measurement is taken per day, and the at least one daily bG measurement corresponds to one or more daily events for the person; recording the measured bG levels in a computing device; determining, by the computing device, whether the recorded bG levels are below, within, or above one or more predetermined bG ranges; an automatically providing, by the computing device, therapeutic guidelines to the person, based on whether the recorded bG levels are below, within, or above the one or more predetermined bG ranges. | 2011-08-25 |
20110208028 | DEVICE FOR MEASURING IMPEDANCE OF BIOLOGIC TISSUES - A device for measuring impedance of biological tissue may include a pair of electrodes for contacting the biological tissue, and a drive circuit coupled to the pair of electrodes and configured to drive an alternating current (AC) through the biological tissue and to sense an AC voltage. The AC voltage is towards a reference voltage on at least one of the pair of electrodes. The device may include at least one single-ended amplitude modulation (AM) demodulator configured to demodulate the AC voltage and to generate a corresponding baseband voltage representing the impedance, and an output circuit configured to generate output signals representative of DC and AC components of the baseband voltage. | 2011-08-25 |
20110208029 | DEVICE FOR STIMULATING LIVING TISSUE BY MICROELECTRODES AND REMOVABLE MODULE AND USE THEREOF - The disclosure relates to a device for stimulating living tissue, comprising an array of stimulating microelectrodes that are placed in a defined configuration side by side and able to be selected by applying an electrical signal for stimulation by one of the microelectrodes. According to the disclosure, an additional conducting surface for application against the living tissue, is provided in the vicinity of a defined plurality of sections for local application of microelectrodes, connecting means being provided for electrical connection between the zones, and the additional conducting surface being also connected to a lead and being formed so as to ensure local stimulation via a microelectrode. | 2011-08-25 |