34th week of 2008 patent applcation highlights part 33 |
Patent application number | Title | Published |
20080199340 | Screw Displacement Pump - The invention relates to a screw pump of single-entry, double-shaft construction with an external bearing of the two screw shafts ( | 2008-08-21 |
20080199341 | MOTOR AND METHOD OF OPERATING THE SAME - A motor and a method of operating the motor are described. The motor may have a female rotor shaft having mounted thereon a female compression rotor, a female power rotor, and a spur gear. The motor may also have a male rotor shaft having mounted thereon a male compression rotor, a male power rotor and a power rotor gear. A housing containing the foregoing may have a front housing plate, a compression rotor case, an isolator plate, a power rotor case, a rear housing plate, and a gear cover adjacent the rear housing plate. The various female and male rotors are engaged with one another within the housing. | 2008-08-21 |
20080199342 | Vacuum Pump for Vehicle Motors and a One-Way Valve for Said Vacuum Pump - The invention relates to a vacuum pump ( | 2008-08-21 |
20080199343 | Method for bonding powder metallurgical parts - Method for forming a unitary component from a plurality of powder metallurgy compacts. The method in some embodiments includes fluidizing first and second surfaces, wherein a first powder metallurgy compact defines the first surface and a second powder metallurgy compact defines the second surface. The method also includes joining the fluidizing first and second surfaces to form a bonded structure and thermally treating the bonded structure to fuse the first and second compacts into a unitary component. | 2008-08-21 |
20080199344 | METHOD OF BUILDING UP AN ALUMINUM ALLOY PART - A method of building up an aluminum alloy part by welding, the method comprising the steps of:
| 2008-08-21 |
20080199345 | Austenitic Lightweight Steel and Use Thereof - Austenitic lightweight steel with a characteristic value of the cold formability higher than 30,000 MPa %, with tensile strengths between 600 and 800 MPa, and fracture strains over 50% has a chromium content of >2.0%<18%, a silicon content of >1.0%<4%, a manganese content of >2.0%<20%, an aluminum content of >0.05%<4%, wherein the steel is within an alloying range determined by | 2008-08-21 |
20080199346 | WELD METAL OF HIGH-STRENGTH CR-MO STEEL - A weld metal of a high-strength Cr—Mo steel formed by shielded metal arc welding contains: 0.04 to 0.10% by mass C, 0.15 to 0.5% by mass Si, 0.5 to 1.0% by mass Mn, 2.00 to 3.25% by mass Cr, 0.9 to 1.2% by mass Mo, 0.01 to 0.03% by mass Nb, 0.2 to 0.7% by mass V, 0.003% by mass or below and above 0% by mass B, 0.02 to 0.05% by mass O, and the balance of Fe and inevitable impurities. A residual extracted by electrolytic extraction from only an unaffected zone of the weld metal contains precipitated Cr in a Cr content below 0.3% by mass, and precipitated Nb in a Nb content of 0.005% by mass or above. | 2008-08-21 |
20080199347 | Method of Producing High-Strength Steel Plates with Excellent Ductility and Plates Thus Produced - Steel sheet, the composition of the steel of which comprises, the contents being expressed by weight: 0.08%≦C≦0.23%, 1%≦Mn≦2%, 1≦Si≦2%, Al≦0.030%, 0.1%≦V≦0.25%, Ti≦0.010%, S≦0.015%, P≦0.1%, 0.004%≦N≦0.012%, and, optionally, one or more elements chosen from: Nb≦0.1%, Mo≦0.5%, Cr≦0.3%, the balance of the composition consisting of iron and inevitable impurities resulting from the smelting. | 2008-08-21 |
20080199348 | Elemental material and alloy - A Ti powder is made b y the subsurface reduction of TiCl | 2008-08-21 |
20080199349 | High performance alloys with improved metal dusting corrosion resistance - Alloy compositions which are resistant to metal dusting corrosion are provided by the present invention. Also provided are methods for preventing metal dusting on metal surfaces exposed to carbon supersaturated environments. The alloy compositions include an alloy (PQR), and a multi-layer oxide film on the surface of the alloy (PQR). The alloy (PQR) includes a metal (P) selected from the group consisting of Fe, Ni, Co, and mixtures thereof, an alloying metal (Q) comprising Cr, Mn, and either Al, Si, or Al/Si, and an alloying element (R). When the alloying metal (Q) includes Al, the multi-layer oxide film on the surface of the alloy includes at least three oxide layers. When the alloying metal (Q) includes Si, the multi-layer oxide film on the surface of the alloy (PQR) includes at least four oxide layers. When the alloying metal (Q) includes Al and Si, the multi-layer oxide film on the surface of the alloy (PQR) includes at least three oxide layers. The multi-layer oxide film is formed in situ during use of the alloy composition in a carbon supersaturated metal dusting environment. Advantages exhibited by the disclosed alloy compositions include improved metal dusting corrosion resistance at high temperatures in carbon-supersaturated environments having relatively low oxygen partial pressures. The disclosed alloy compositions are suitable for use as the inner surfaces in reactor systems and refinery apparatus. | 2008-08-21 |
20080199350 | Metastable beta-titanium alloy - Metastable β-titanium alloy contains, in mass %: from 1.5 to 3.5 aluminum; from 4.5 to 8.0 molybdenum; from 1.0 to 3.5 vanadium; from 1.5 to 3.8 iron; titanium balance. This alloy combines high strength and ductility. This allows to use it for production of a wide range of critical parts including fastener components and different coil springs (e.g. in automobile industry). | 2008-08-21 |
20080199351 | ZERO YIELD REACTOR AND METHOD OF SANITIZING AIR USING ZERO YIELD REACTOR - An apparatus (and method) for sanitizing air includes a generating unit that generates reactive oxygen species and ozone from oxygen in air, received by the generating unit, to be sanitized, and a cancellation unit or conversion filter that cancels at least a portion of the ozone before the air is returned to an area to be sanitized. | 2008-08-21 |
20080199352 | Ex vivo antimicrobial devices and methods - A method and device for destroying and inhibiting exposure to microbes and infection includes a first element and a second element, and a power source. At least one of the elements includes antimicrobial metal, which, when energized by the power source, produces ions that are lethal to microbes. The device can be incorporated into virtually any useful object. During normal use of the object, electrical communication is established between the two elements, causing current supplied from the power source to flow through the antimicrobial metal. The two elements are configured and arranged to ensure that ions flowing from the antimicrobial metal flow through the region in which it is desired to kill microbes. The antimicrobial metal can be on the surface of the element, incorporated into the material making up the element, or provided in any other way that allows the antimicrobial effect to be achieved. | 2008-08-21 |
20080199353 | Ultraviolet Sanitization In Pharmacy Environments - Systems and methods to reduce bioburden on at least a portion of a fluid transfer port include supplying a dose of radiation to the portion in optical communication with at least one source of radiation. In an illustrative example, a medical container, such as a vial or IV bag, receives a dose of ultraviolet (UV) energy substantially at a predetermined region of a fluid transfer site. In some examples, such a sanitization process may precede a fluid transfer operation in which a fluid is transferred into or out of the medical container by passing through the sanitized region. Such fluid transfers may be used in automated or semi-automated pharmaceutical processes, such as drug reconstitution. Various embodiments may further include one or more seal assemblies, each seal assembly having an aperture through which the radiation dose is supplied from the source to a controlled region on the fluid transfer port. | 2008-08-21 |
20080199354 | HAND SANITIZER/STERILIZER - A germicidal system and method for deactivating pathogens on the surface of a bodily extremity protected by a prophylactic covering substantially opaque to UV-C radiation. The device includes an enclosure having one or more openings through which the extremity can be inserted. The enclosure contains a radiation source configured to produce germicidal radiation having a wavelength of about 253.7 nm. The openings are configured relative to the radiation source such that the inserted extremity is in close proximity to the radiation source. The prophylactic covered extremity is preferably a gloved hand thereby sanitizing the surface of the glove. The extremity inserted is preferably exposed for a predetermined period of time to ensure a desired level of sanitization. Optionally, the device can include an orientation detector to determine the position of the user's hand and the spread of the user's fingers, and a surface detector to determine whether the user's hand is covered by a glove. | 2008-08-21 |
20080199355 | Membrane Concentrator - Apparatus for concentrating a nebulant comprising a nebulant flow conduit and a counter-flow conduit, or preferably, a plurality of alternating nebulant flow conduits and corresponding counter-flow conduits eg in layered or coaxial arrangement, and wherein at least a portion of the nebulant flow conduit and said counter-flow conduits define respective opposed sides of a gas permeable membrane. In use a nebuliser is in communication with the nebulant flow conduit and the nebulant flow and counter-flow are in the same or opposite directions and act to concentrate the amount of active in a droplet eg from 35 wt % to 60 wt % hydrogen peroxide in water to disinfect and/or sterilize an article. | 2008-08-21 |
20080199356 | System with adapter for cleaning medical appliances - An adapter ( | 2008-08-21 |
20080199357 | Integrated centrifugal blood pump-oxygenator, an extracorporeal life support system and a method of de-bubbling and priming an extracorporeal life support system - The invention relates to an integrated centrifugal blood pump-oxygenator ( | 2008-08-21 |
20080199358 | AUTOMATIC ANALYZER - An object of the present invention is to provide an automatic analysis method and an automatic analyzer which are suitable for improving throughput by changing reagents during analysis without placing a load on an operator, and without stopping the analysis. There is provided an automatic analysis method comprising the steps of: while moving a reagent transfer mechanism with respect to a reagent pipettor, dispensing a reagent placed in the reagent transfer mechanism by use of the reagent pipettor to cause a sample to react with the dispensed reagent; and measuring the reacted sample so as to analyze specified analysis items of the sample. A reagent is transferred from a reagent storage unit to a reagent changing mechanism. Then, the reagent changing mechanism is moved in synchronization with the reagent transfer mechanism so that reagents are changed during the synchronization. | 2008-08-21 |
20080199359 | Soil Moisture Sensor - A soil moisture sensor which includes a processor to derive soil moisture values and a memory store associated with said processor to store measured values on a periodic basis, wherein the processor scales the stored moisture values to establish a moisture range for the sensor that can be used to calibrate each new reading. The sensor includes a capacitive sensor. In one embodiment the processor measures the capacitance at a single frequency and also measures the phase and amplitude to derive measures of soil impedance due to moisture content and conductivity. In another embodiment the soil sensor capacitor is part of a resonant circuit and the resonant frequency of the circuit is measured as an indication of soil moisture. The sensor is constructed on a single substrate, which also functions as its own insertion stake into the soil. | 2008-08-21 |
20080199360 | Method and composition for a platinum embedded sol gel optical chemical sensor with improved sensitivity and chemical stability - A process for manufacturing a material, (medium or matrix) to hold or encapsulate sensing molecules with enhanced sensitivity to oxygen gas and dissolved oxygen by mixing a platinum compound with sol-gel monomers and then coating the tip of an optical fiber is disclosed. The sol-gel polymerizes, trapping the platinum compound in an oxygen permeable glass like solid. The high quenching efficiency of the Pt compound upon oxygen exposure makes the sensor extremely sensitive to oxygen partial pressure variations and also resistant to exposure to hydrocarbons. | 2008-08-21 |
20080199361 | Hand-held pipetting device - A hand-held pipetting device for drawing liquid into and dispensing liquid from a pipette includes head and handle portions that are rotatably connected together. One or more extender modules may be connected between the head and handle portions. The handle portion includes a normally biased trigger mechanism that crimps flexible aspirating and dispensing conduits. Pressure against the conduits may be released by squeezing the trigger mechanism so that one or more of the conduits is partially or fully opened. A pipette holder is rotatably and removably connected to the head portion. When the holder is rotated, the attached pipette can be positioned generally vertically or at an angle with respect to the pipetting device. | 2008-08-21 |
20080199362 | Microfluidics Package and Method of Fabricating the Same - A microfluidics package ( | 2008-08-21 |
20080199363 | POROUS BARRIER MEDIA COMPRISING COLOR CHANGE INDICATORS - The present invention provides porous barrier compositions comprising color change indicators and methods of making and using the same. | 2008-08-21 |
20080199364 | Containers for reading and handling diagnostic reagents and methods of using the same - A container with a rotatable lid for reading and handling diagnostic reagents in tape form comprising a body portion, a lid portion, a continuous tape, a reagent-sensing device, and a storage device. The body portion includes an inner and outer surface. The lid portion is attached to the body portion and is adapted to rotate from a closed position to an open position. The continuous tape includes a diagnostic reagent. The reagent-sensing device is attached to either the body portion or the lid portion and adapted to read the diagnostic reagent. The storage device is attached to the body portion that is adapted to hold and dispense an unused portion of the continuous tape. During the rotation of the lid portion, the continuous tape is advanced from the first storage device and is extended over the reagent-sensing device. | 2008-08-21 |
20080199365 | Planar registration of multi-well plate from well side - A multi-well plate such as a microtiter plate is secured from its well side in a manner that corrects or compensates for any deviations of the plate base from a planar configuration. This is achieved by an apparatus that includes an array of posts with exposed tips that define a plane, a plurality of movable collets that, when appropriately actuated, seize the walls of selected wells, and a biasing means to urge the collets in a direction that forces the wells of the microtiter plate against the exposed tips of the posts. | 2008-08-21 |
20080199366 | Holder for specimen cup - The present invention comprises a holder for a specimen cup, the holder comprising a curved member with a handle and a lever extending continuously therefrom. The curved member receives, engages, and grips the specimen cup. The handle provides a means to hold and carry the specimen cup without soiling one's hands. In addition, the handle and lever spread to expand the curved member's arc, thereby releasing the holder's grip on the specimen cup. | 2008-08-21 |
20080199367 | Indoor air freshener - An air is dehumidified by a dehumidifier. Then the dehumidified air is heated, sterilized and deodorized at an air outlet. | 2008-08-21 |
20080199368 | Night soil drying treatment apparatus - Foreign objects such as carbide and so forth are prevented from being adhered, solidified, accumulated in the interior of a drying cauldron every time drying treatment of night soil is completed, and heat transfer by a cauldron bottom heater caused by the accumulation of foreign objects is not prevented, thereby smoothly implementing treatment of next cycle and succeeding treatment. In a night soil drying treatment apparatus wherein when night soil inside the night soil tank is sucked up and thrown into a drying cauldron and a load of night soil to be treated is stored in the drying cauldron, the drying cauldron is heated to evaporate night soil in the drying cauldron, and completing night soil drying treatment upon completion of heating and evaporating treatment by a predetermined time, there is provided a washing mechanism for removing adherents onto the interior of the drying cauldron for jetting water toward the interior of the drying cauldron every time one cycle of night soil treatment is completed, thereby automatically washing the interior of the drying cauldron to remove the adherents onto the interior of the drying cauldron. | 2008-08-21 |
20080199369 | Extruded porous substrate and products using the same - A highly porous substrate is provided using an extrusion system. More particularly, the present invention enables the production of a highly porous substrate. Depending on the particular mixture, the present invention enables substrate porosities of about 60% to about 90%, and enables advantages at other porosities, as well. The extrusion system enables the use of a wide variety of fibers and additives, and is adaptable to a wide variety of operating environments and applications. Fibers, which have an aspect ratio greater than 1, are selected according to substrate requirements, and are typically mixed with binders, pore-formers, extrusion aids, and fluid to form a homogeneous extrudable mass. The homogeneous mass is extruded into a green substrate. The more volatile material is preferentially removed from the green substrate, which allows the fibers to form interconnected networks. As the curing process continues, fiber to fiber bonds are formed to produce a structure having a substantially open pore network. The resulting porous substrate is useful in many applications, for example, as a substrate for a filter or catalyst host, or catalytic converter. | 2008-08-21 |
20080199370 | Efficient infrared-based reaction vessel - The present invention provides an efficient infrared (IR) reaction vessel system that includes an infrared reaction vessel having an optical window into a reaction reservoir that absorbs minimal infrared energy, a male cap attached to the reaction vessel that allows precise positioning with respect to an infrared heat source, and at least one access tube passing through the cap. The infrared reaction vessel of the present invention further provides vacuum lines that also repulse ions and minimize evaporation loss and novel temperature control feedbacks such as the use of a proximally positioned resistive thermal device (RTD). | 2008-08-21 |
20080199371 | Microfluidic Device for Patterned Surface Modification - A microfluidic device and its use for the production of micro-arrays, in particular for the detection of protein interactions, is described. Said microfluidic device comprises a flow cell part ( | 2008-08-21 |
20080199372 | Thermochemical Reactor for a Cooling and/or Heating Apparatus - The invention relates to a thermochemical reactor ( | 2008-08-21 |
20080199373 | METHOD AND DEVICE FOR THE PRODUCTION OF ALKYLATES - Disclosed is a device for the production of alkylate(s) by sulfuric acid alkylation of at least one isoparaffin such as isobutane with at least one olefin, such as butylenes. The device includes a mixing chamber for preparing a mixture of the isoparaffin with recycled reaction products. It also includes an emulsion chamber for preparing a first hydrocarbons-in-sulfuric acid emulsion, where the mixture prepared in the mixing chamber is injected in multiple parallel jets into a sulfuric acid composition. The device further includes a pre-reaction chamber for preparing a second emulsion, where a given portion of the olefin is injected in jet streams into the first hydrocarbons-in-sulfuric acid emulsion coming from the emulsion chamber. Last of all, the device includes a reaction chamber of given height and cross-section where the second emulsion coming from the pre-reaction chamber is injected through nozzles and another portion of olefin is injected in jet streams all over the cross-section and height of the reaction chamber. The reaction chamber is devised so that the second emulsion is circulated in a closed circuit and it has an outlet through which a balanced amount of reaction mixture is continuously discharged. All of said mixing chamber, emulsion chamber, pre-reaction chamber and reaction chamber are coaxially arranged one above the other in vertical position and altogether form a reactor with the prechamber being located at the bottom of the reactor and the reaction chamber on top thereof. A method for the production of alkylates by means of the above device is also disclosed. | 2008-08-21 |
20080199374 | A Method For Arranging A Chemical Barrier In A Gasifying Reactor For Black Liquor, A Chemical Gasifying Reactor, A Barrier Layer Of A Reactor And A Method For Manufacturing A Building Block For Such a Barrier Layer - A chemical reactor and a method for arranging a ceramic barrier in a gasifying reactor, which reactor is arranged to convert high energy organic waste of black liquor type with a large amount of organic or inorganic alkali metal compounds, by high temperature oxidation with air or oxygen, whereby the organic waste is converted to a hot reducing gas containing a considerable amount of water vapour and the inorganic compounds form an alkali-containing salt melt at a temperature of 750-1150° C., and which reactor is arranged to comprise an outer shell ( | 2008-08-21 |
20080199375 | Installation and Device for Guiding a Gas for Devices Used to Treat Granular Products by Drying, Film Coating and Coating - The invention relates to an installation ( | 2008-08-21 |
20080199376 | Catalytic Reactive Component Reduction System and Methods for the Use Thereof - In accordance with the present invention, there are provided simplified systems and methods for catalytically deactivating, removing, or reducing the levels of reactive component(s) from the vapor phase of fuel storage tanks. The simple apparatus described herein can be utilized to replace complex OBIGGS systems on the market. Simply stated, in one embodiment of the invention, the vapor phase from the fuel tank is passed over a catalytic bed operated at appropriate temperatures to allow the reaction between free oxygen and the fuel vapor by oxidation of the fuel vapor, thus deactivating reactive component(s) in the gas phase. | 2008-08-21 |
20080199377 | Exhaust filter system for non-road engine - An exhaust filter system, adapted for removing substances entrained in an exhaust gas from a nonroad engine, includes a casing having a filter cavity for communicating with an exhaust outlet of the generator and a filter core which includes a plurality of filtering loops, each having a plurality of air pores, coaxially received in the filter cavity, a plurality of filtering spacers each having a plurality of air meshes and positioned between each two filtering loops to define a plurality of air passages therebetween, and a catalyzing element for chemically reacting with the substances of the exhaust gas. Therefore, when the exhaust gas passes through the air passages of the filter core, the exhaust gas is evenly diffused to the filter cavity through the air pores and the air meshes so as to enhance a chemical reaction of the exhaust gas with the catalyzing element. | 2008-08-21 |
20080199378 | Process for disposing waste gas comprising sulfur oxides and apparatus thereof - A method for enlarging the particle diameters of sulfuric acid mists in waste gas and collecting the sulfuric acid mists in high efficiency is provided. A process for disposing waste gas containing sulfur oxides that introduces the waste gas in dry type electrostatic precipitator to remove dusts and then introduces the waste gas in a wet desulfurization apparatus to carry out desulfurization, wherein outside air with a flow rate at which the waste gas introduced in the wet desulfurization apparatus is the dew point of acid is taken in from an introducing tube to mix the outside air in the waste gas. | 2008-08-21 |
20080199379 | Method and Device For Removing Sulphur Dioxide From a Dry Gas Stream - The invention relates to a method for removing sulfur dioxide from a dry gas stream which comprises following steps:
| 2008-08-21 |
20080199380 | Carbon Monoxide Removal Method, Operating Method for Fuel Reforming System, Carbon Monoxide Remover, Fuel Removal System Having the Carbon Monoxide Remover, and Filter - In operating the carbon monoxide removal reactor or the fuel reforming system, there is provided a technique for removing carbon monoxide in a stable manner for an extended period of time. In a method of removing carbon monoxide including an introducing step of introducing a reactant gas including mixture gas and an oxidizer added thereto to a carbon monoxide removal reactor forming in its casing a catalyst layer comprising a carbon monoxide removal catalyst for removing carbon monoxide contained in the mixture gas and a removing step of removing the carbon monoxide by causing the oxidizer to react with the mixture gas on the carbon monoxide removal catalyst, in said introducing step, the reactant gas of 100° C. or lower is introduced to the carbon monoxide removal reactor. | 2008-08-21 |
20080199381 | Process For the Production of Inp Fine Particles and Inp Fine Particle Dispersion Obtained by the Process - The invention is to provide a process for industrially advantageously producing InP fine particles having a nano-meter size efficiently in a short period of time and an InP fine particle dispersion, and there are provided a process for the production of InP fine particles by reacting an In raw material containing two or more In compounds with a P raw material containing at least one P compound in a solvent wherein the process uses, as said two or more In compounds, at least one first In compound having a group that reacts with a functional group of P compound having a P atom adjacent to an In atom to be eliminated with the functional group in the formation of an In—P bond and at least one second In compound having a lower electron density of In atom in the compound than said first In compound and Lewis base solvent as said solvent, and InP fine particles obtained by the process. | 2008-08-21 |
20080199382 | Process For the Preparation of a Biomimetic Bone Substitute and Its Uses - The object of the present invention is a process for obtaining a bone substitute of given chemical and physical characteristics and entirely similar to those of the mineral portion of natural bone tissue. | 2008-08-21 |
20080199383 | FABRICATION OF QUARTZ-CLAD CARBON NANOTUBE BUNDLES - [Objective] To develop a method of fabricating carbon nanotube bundles clad in a quartz sheath with high temperature and chemical resistance. | 2008-08-21 |
20080199384 | Process For Producing Silica, Sodium Sulfite and Sodium Hydrogen Sulfite With Sodium Sulfate - The present invention provides a process for producing silica, sodium sulfite and sodium hydrogen sulfite with sodium sulfate, wherein quartz sand, sodium sulfate and carbon are mixed and charged into a furnace for reaction and the obtained solid sodium silicate and sulfur dioxide are used to prepare silica, sodium sulfite and sodium hydrogen sulfite according to the following steps: 1) To produce silica: said solid sodium silicate is dissolved in water and filtered to produce a water glass solution; then sulfuric acid is reacted with said water glass solution to produce precipitated silica and sodium sulfate; and the precipitated silica is washed, filtered, liquefied and dried to produce silica; 2) To produce sodium sulfite: soda is added into a sodium hydrogen sulfite solution to produce sodium sulfite solution; one part of said sodium sulfite solution is concentrated and evaporated to obtain dry sodium sulfite; and the other part of the sodium sulfite solution is reacted with the sulfur dioxide produced during the production of the sodium silicate to produce sodium hydrogen sulfite solution, which can be recycled and reused in step (2); 3) To produce sodium hydrogen sulfite: soda is added into a sodium hydrogen sulfite solution followed by reacting with the sulfur dioxide produced during the production of the sodium silicate to produce a supersaturated sodium hydrogen sulfite solution, which is crystallized and dried to obtain a dry solid sodium hydrogen sulfite. The process of the present invention produces various products at low production cost and without causing environmental problems, and thus it has great practical value. | 2008-08-21 |
20080199385 | Process for Producing Silica and Sodium Sulfite with Sodium Sulfate - Provided is a process for producing silica and sodium sulfite with sodium sulfate, wherein a mixture of quartz sand, sodium sulfate and carbon is reacted to produce solid sodium silicate and sulfur dioxide, which are used to produce silica and sodium sulfite through the following steps: (1) Said solid sodium silicate is dissolved in water and then filtered to obtain a sodium silicate solution; a sodium hydrogen sulfite solution is added to said sodium silicate solution to produce precipitated silica and sodium sulfite solution and the resultant mixture is filtered; (2) One part of the filtrate obtained at the end of step (1) is brought into contact with said sulfur dioxide and the product, sodium hydrogen sulfite, is recycled to step (1); (3) The filter cake obtained at the end of step (1) is acidified, followed by filtration, washing and drying to obtain silica; and (4) The other part of the filtrate obtained at the end of step (1) is concentrated and dried to obtain solid sodium sulfite. The process of the present invention is of great industrial value due to its simple steps, useful by-products and low production cost. | 2008-08-21 |
20080199386 | Method for producing ammonium hexachlororuthenate and ruthenium powder, as well as ammonium hexachlororuthenate - Ammonium hexachlororuthenate is produced by adding ammonium chloride to a hydrochloric acid solution containing ruthenium. The ammonium hexachlororuthenate is baked to obtain the ruthenium powder. When the moisture content of the ammonium hexachlororuthenate is high, the baked product is so hard sintered product that its pulverization is not easy. In accordance with the present invention, the following steps are carried out. Hydrochloric acid solution containing ruthenium is held at a temperature of 80 to 95° C. for three hours or longer. The ammonium chloride is then added to the hydrochloric acid solution which is stirred by a stirring mill at the rotation of 200 revolutions per minute or more. The hydrochloric acid solution is held at a temperature of from 85 to 95° C. for 1 hour while being stirred at 200 rpm. The resultant precipitate of ammonium hexachlororuthenate is filtered. The inventive crystals of precipitated ammonium hexachlororuthenate has 10 mass % or less of moisture content. | 2008-08-21 |
20080199387 | Surface Treatment of Carbon Microfibers - A method of oxidizing the surface of carbon microfibers that includes contacting the microfibers with an oxidizing agent that includes sulfuric acid and potassium chlorate under reaction conditions sufficient to oxidize the surface. The invention also features a method of decreasing the length of carbon microfibers that includes contacting the microfibers with an oxidizing agent under reaction conditions sufficient to decrease the length. | 2008-08-21 |
20080199388 | Method for manufacturing a diamond composite - A method for manufacturing a diamond composite, includes: a) mixing diamonds with additives, the mixture comprising at least 50 wt % and less than 95 wt % of diamonds and more than 5 wt % additives; b) forming a work piece from the mixture using a pressure of at least 100 Mpa; c) heating the formed work piece to at least 300° C. for removing possible water and wholly or partially removing additives; d) heating the work piece and controlling the heating temperature and heating time so that a certain desired amount of graphite is created by graphitization of diamonds, wherein the amount of graphite created by graphitization is 3-50 wt % of the amount of diamond; e) infiltrating silicon or silicon alloy into the work piece. | 2008-08-21 |
20080199389 | Method and device for producing carbon nanotubes - Methods and devices for producing carbon nanotubes are disclosed herein. These methods and devices are based on chemical vapor deposition (CVD) in an open environment under atmospheric pressure, which eliminates the need for a vacuum chamber or evacuation process to remove oxygen and/or impurities prior to carbon nanotube growth. | 2008-08-21 |
20080199390 | Enhanced Directional Conductivity Of Graphitizable Foam - A graphitizable carbon foam having enhanced directional thermal conductivity is provided. The mesophase portions of a mesophase pitch are aligned with each other to create an oriented mesophase pitch, which is then foamed to provide an oriented pitch foam. The pitch foam can be heated to carbonize the pitch thereby forming an oriented carbon foam. The carbon foam can be further heated to provide an oriented graphite foam. | 2008-08-21 |
20080199391 | Method for circuits inspection and the method of the same - A method for circuit inspection comprises steps of providing a substrate having a conductive line; and forming a metal layer on at least the conductive layer to increase a contrast between the conductive layer and adjacent area for the circuit inspection. The method further comprising removing the metal layer. The metal layer is removed by a mixture of nitric acid, hydrogen peroxide and fluoride boric acid. The metal includes Silver, Nickel or Tin. The deposit metal can be removed by inter diffusion and form intermetallic compounds (for example Cu | 2008-08-21 |
20080199392 | Mixed Oxide Powder Comprising Alkali Metal Oxide, and Silicone Rubber Comprising This Powder - Alkali metal oxide-metal oxide mixed oxide powder in the form of aggregates of pore-free primary particles, comprising from 0.005 to 5% by weight of at least one alkali metal oxide, which has a BET surface area of from 100 to 350 m/g, has a specific DBP number, expressed as DBP number per square metre of specific surface area, greater than or equal to that of a powder which has only the metal oxide component, has the alkali metal oxide distributed in the core and on the surface of the primary particles. Silicone rubber comprising the alkali metal oxide-metal oxide mixed oxide powder. | 2008-08-21 |
20080199393 | Inorganic Compounds - Disclosed is a niobium suboxide powder for the manufacture of capacitors with higher break down voltages, higher temperatures of operation and elongated lifetimes. The powder is doped with nitrogen which is at least partly present in the form homogeneously distributed, x-ray detectable Nb | 2008-08-21 |
20080199394 | Method for obtaining the nano-scale acicular oxidation compound powder - The invention, firstly, SnCl | 2008-08-21 |
20080199395 | Reversible Hydrogen Storage Composition, Method of Making and Uses of Said Composition - The invention relates to a reversible hydrogen storage composition comprising lithium hydride which desorbs hydrogen when heated in a hydrogen environment to a temperature of 470° C. or more to form a hydrogenated state, and absorbs hydrogen when cooled to 420° C. or less, the temperatures of absorption and desorption being independent of the pressure of the hydrogen environment. A partially processed blend of powdered lithium hydride and catalytic amounts of other elements such as Fe, B, Ni, Co or C, added as micron or sub-micron sized powders and still present in the blend as a pure phase, can provide improved hydrogen storage. | 2008-08-21 |
20080199396 | Radioisotope Labelled Biological Compositions, And Their Use In Accelerator Mass Spectrometry - The invention provides a biological composition comprising a biological compound of formula I | 2008-08-21 |
20080199397 | Use of a Tetrapeptide Acsdkp Analogue Resistant to the Angiotensin i Conversion Enzyme, for Measuring Glomerular Filtration Rate in a Human or an Animal and Kit Containing Same - The invention concerns the use of ACE-resistant N-acetyl-Ser-Asp-Lys-Pro analogues for preparing a reagent or marker adapted to measure a glomerular filtration rate. | 2008-08-21 |
20080199398 | Novel Peptides That Promote Lipid Efflux - Disclosed herein are peptides with domains that promote lipid efflux from cells and optionally possess at least one anti-inflammatory domain or a domain that stimulates LCAT activity. Provided herein are methods of using the peptides to treat or inhibit diseases including dyslipidemic disorders, stroke and myocardial infarction. Also provided are methods of detecting plaque in vessels using the labeled peptides of the present invention. | 2008-08-21 |
20080199399 | Interfacing Nanostructures to Biological Cells - Disclosed herein are methods and materials by which nanostructures such as carbon nanotubes, nanorods, etc. are bound to lectins and/or polysaccharides and prepared for administration to cells. Also disclosed are complexes comprising glycosylated nanostructures, which bind selectively to cells expressing glycosylated surface molecules recognized by the lectin. Exemplified is a complex comprising a carbon nanotube functionalized with a lipid-like alkane, linked to a polymer bearing repeated α-N-acetylgalactosamine sugar groups. This complex is shown to selectively adhere to the surface of living cells, without toxicity. In the exemplified embodiment, adherence is mediated by a multivalent lectin, which binds both to the cells and the α-N-acetylgalactosamine groups on the nanostructure. | 2008-08-21 |
20080199400 | Otologic nanotechnology - Diagnosing or treating a human ear includes transporting a conjugated nanoparticle or a magnetically responsive nanoparticle into a human's middle or inner ear. Otologic nanophoresis includes electrically, magnetically or electromagnetically driving a nanoparticle through a membrane of the ear, including a tympanic membrane, a round window membrane, an oval window membrane, or a circulatory membrane. An otologic diagnostic device includes a nanoparticle conjugated with a material selected from the group consisting of lipids, proteins, growth factors, growth hormones, antioxidants, free radical scavengers, steroid preparations, and metabolically active substances; an otologic therapeutic device includes the same categories of substances and chemotherapeutic drugs. Another otologic composition includes a nanoparticle conjugated with a substance perceptible to magnetic resonance imaging. | 2008-08-21 |
20080199401 | Method for Dissolution of Gases with Short-Lived Physical Properties in a Liquid - The invention relates to a process for dissolving a gas with short-lived physical properties in a liquid, comprising the steps of providing the gas with short-lived physical properties, providing the liquid and bringing the gas with short-lived with short-lived physical properties is fed into the liquid via a semi-permeable membrane that is permeable to gas. | 2008-08-21 |
20080199402 | Contrast Agents - The present invention relates to iodine containing compounds containing a central cyclopropane scaffolding moiety allowing for the arrangement of three iodinated phenyl groups bound thereto. | 2008-08-21 |
20080199403 | Composition and Method for Direct Visualization of the Human Appendix - A positive contrast agent composition containing meglumine diatrizoate, sodium diatrizoate, simethicone, famotidine and aspartame in predetermined amounts that is orally administered to a patient for clinical evaluations of appendicitis wherein a positive contrast effect is achieved. Methods of use include orally administering individual doses of the composition approximately 50 minutes prior to appendix visualization using computerized axial tomography. | 2008-08-21 |
20080199404 | Contrast Agents - The present invention relates to a class of compounds and to diagnostic compositions containing such compounds where the compounds are iodine containing compounds. More specifically the iodine containing compounds are chemical compounds containing an aliphatic central moiety allowing for the arrangement of three iodinated phenyl groups bound thereto. | 2008-08-21 |
20080199405 | Compounds and methods for immunotherapy and diagnosis of tuberculosis - Compounds and methods for inducing protective immunity against tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one immunogenic portion of one or more | 2008-08-21 |
20080199406 | Verification Method - The present invention relates to a verification method of tablets, in particular pharmaceutical tablets. It further relates to an invisible secure marking or information which is a part of such tablet. The invention further relates to tablets suitable for such verification method, to processes for manufacturing such tablets and methods for reading the information. | 2008-08-21 |
20080199407 | Drug Detoxification Protocol Using Microdosing - This invention relates to use of an opioid receptor agonist in microdose quantities to reduce or eliminate the withdrawal symptoms associated with discontinuing drug use. The dosage of the agonist is reduced over an extended period of time. | 2008-08-21 |
20080199408 | Azeotropic fumigant compositions of methyl iodide - Azeotropic and azeotrope-like compositions of methyl iodide and at least one fluorocarbon or hydrofluorocarbon such as 1,1,1,3,3-pentafluoropropane (HFC-245fa). The compositions are present as a gas, at temperatures of about 30° C. or below. The inventive compositions serve as a non-ozone-depleting gaseous fumigant which is useful in a variety of applications, in place of methyl bromide. These compositions serve as a drop-in replacement for gaseous methyl bromide, providing the benefits of a methyl iodide fumigant while also utilizing existing methyl bromide equipment. | 2008-08-21 |
20080199409 | Effervescent Acidified Rehydration Preparations - An effervescent acidified rehydration preparation for administration in the drinking water of mammals and poultry includes an amount of a dry generally water soluble acidified electrolyte composition for treatment of dehydration in animals including mammals and poultry by oral administration in the drinking water of animals of interest and an amount of a pH balanced effervescent composition including an amount of one or more compatible water soluble organic acid species and an amount of one or more water soluble effervescent agents wherein effervescence occurs immediately upon the rehydration preparation being added to water. | 2008-08-21 |
20080199410 | Pulmonary surfactant formulations and methods for promoting mucus clearance - Methods and compositions to enhance mucus clearance and to treat of pulmonary lung disorders such as cystic fibrosis are disclosed. The methods utilize pulmonary surfactants, alone or combined with hyperosmotic agents, administered to patients in an amount effective to enhance mucus clearance. The compositions comprise a pulmonary surfactant combined with an osmotically active agent. | 2008-08-21 |
20080199411 | Cosmetic Composition Comprising as Antiperspirant Agent a Flocculating Water-Soluble Polymer; Process For Treating Perspiration - The invention relates to a cosmetic composition comprising at least one aqueous phase and at least one antiperspirant active agent, characterized in that the said antiperspirant active agent consists of at least one flocculating water-soluble polymer comprising amine groups on the main chain and in that it does not contain any aluminium and/or zirconium antiperspirant salts. | 2008-08-21 |
20080199412 | ANTI-STAINING ANTIBACTERIAL DENTIFRICE - An anti-staining, antibacterial dentifrice comprises an anti-staining effective amount of an orally acceptable polymer or copolymer that comprises a plurality of monomeric groups of formula (I) | 2008-08-21 |
20080199413 | Novel Use of Organic Compounds - The present invention is directed to the use of a compound selected from the group consisting of β-carotene, lutein, lycopene and β-cryptoxanthin, and mixtures thereof and combinations thereof with CoQ-10 for maintaining the energy metabolism, the energy flow and/or the energy production in skin or of skin of animals including humans, for maintaining the respiratory function of the skin of animals including humans, for energizing the skin, maintaining and supporting the radiance and natural glow of the skin of animals including humans and for promoting a healthy appearance of the skin of animals including humans for preventing UV-A radiation-induced mtDNA mutagenesis in skin of animals including humans, as well as for the manufacture of a composition, preferably an orally applicable composition, for these uses and the corresponding methods. The present invention is further directed to the use of a compound selected from the group consisting of β-carotene, lutein, lycopene and β-cryptoxanthin, and mixtures thereof and combinations thereof with CoQ-10 in sunscreens as well as daily care products to improve their photoprotective potential, as well as to their use as effective micronutrients for skin maintenance. Furthermore the present invention is directed to compositions, preferably orally applicable compositions, comprising a certain amount of at least one compound selected from the group consisting of β-carotene, lutein, lycopene and β-cryptoxanthin and mixtures thereof and combinations thereof with CoQ-10 as active ingredient, characterized in that the amount is effective for such uses as mentioned above. | 2008-08-21 |
20080199414 | COSMETIC FORMULATION COMPRISING FLAVONOID DERIVATIVES - The invention relates to cosmetic formulations, pharmaceutical preparations, food products and food supplements containing flavonoid derivatives. The flavonoid derivatives act therein, for instance, as UV filter. Some flavonoid derivatives represent novel compounds. | 2008-08-21 |
20080199415 | COMPOSITIONS CONTAINING A BIMODAL FILM FORMER AND CROSS-LINKED STARCH - The invention relates to compositions containing (a) at least one bimodal film former; and (b) at least one cross-linked starch as well as to methods of using such compositions and kits containing such compositions. | 2008-08-21 |
20080199416 | Use of Anionically and Cationically Ampholytic Copolymers - The present invention relates to the use of an anionically ampholytic or cationically ampholytic copolymer which which is obtainable by free-radical copolymerization of
| 2008-08-21 |
20080199417 | Personal Care Composition Comprising Saccharide-Siloxane Copolymers - A personal care composition comprising at least one saccharide-siloxane copolymer having a saccharide component and an organosiloxane component and linked by a linking group, wherein the saccharide-siloxane copolymer has a specified formula, is provided. The personal care composition is adapted to provide at least one benefit to the at least one portion of the body to which it is applied. Emulsions, methods for preparing emulsions comprising saccharide-siloxane copolymers, and personal care products comprising the personal care compositions and emulsions are also provided. | 2008-08-21 |
20080199418 | Polysiloxane block copolymers - This invention encompasses novel amphiphilic block copolymers comprising polysiloxane blocks and polycationic blocks. The polycationic blocks are formed from diallyldialkylammonium derivatives. The formed block copolymers are particularly useful for treating or conditioning keratinous substances such as hair or skin. | 2008-08-21 |
20080199419 | Use of Water-Soluble Polymers Which are Obtained by Means of Controlled Radical Polymerisation as an Agent For Improving the Opacity and/or Brightness of Dry Products Containing Same - The invention relates to agents that are used to improve optical properties such as opacity and/or brightness of dry products based on mineral matter containing said agents. More specifically, the invention relates to a method of producing dry products based on mineral matter, in which the agents used to improve the opacity and/or brightness of said dry products take the form of controlled-structure water-soluble polymers which are obtained using a controlled radical polymerisation method employing a particular alkoxyamine as a polymerisation initiator. The invention also relates to the use of aqueous suspensions and/or dispersions of mineral matter containing said polymers for the same purpose. The aforementioned dry products comprise plastics, filled paper, dry films produced by drying a coating slip, dry films produced by drying an aqueous paint formulation or dry films produced by drying an aqueous cosmetic formulation, which contain mineral matter as well as said polymers. | 2008-08-21 |
20080199420 | Use Of Polyisobutenyl Succinic Anhydride-Based Block Copolymers In Cosmetic Preparations - The invention relates to novel cosmetic preparations comprising an O/W emulsion, where the O/W emulsion comprises at least one amphiphilic polymer comprising one or more hydrophobic units A and one or more hydrophilic units B, where the hydrophobic units A are formed from polyisobutenes modified with terminal, polar groups, at least one component with an HLB value in the range from 8 to 20, and at least one oil and/or fat phase and water. | 2008-08-21 |
20080199421 | W/O EMULSION - The invention relates to a composition preferably for topical application in the form of a water-in-oil emulsion containing at least one emulsifying silicone elastomer and at least one semi-crystalline polymer. The invention also relates to the use of the composition according to the invention for skincare, and in particular for nourishing the skin, preventing transepidermal water loss and protecting the skin. | 2008-08-21 |
20080199422 | Method for the Treatment of Myelodysplastic Syndromes Using 1-Oxo-2-(2,6-Dioxopiperidin-3-Yl-)-4-Methylisoindoline - Methods of treating, preventing and/or managing myelodysplastic syndromes are disclosed. Specific methods encompass the administration of an immunomodulatory compound, or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer, clathrate, or prodrug thereof, alone or in combination with a second active ingredient, and/or the transplantation of blood or cells. Specific second active ingredients are capable of affecting or blood cell production. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed. | 2008-08-21 |
20080199423 | Methods of Using Apo2l Receptor Agonists and Ink Cell Activators - Methods of enhancing apoptosis or cytolytic activity in mammalian cells using Apo-2L receptor agonists and NK cells, or activating agents thereof, are provided. Apo-2L receptor agonists contemplated for use in the methods include the ligand known as Apo-2 ligand or TRAIL, as well as agonist antibodies directed to one or more Apo-2L receptors. NK cell activating agents contemplated for use in the methods of the invention include but are not limited to Toll receptor activating agents, IL-2, IL-12, IL-15, IFN-alpha, IFN-beta, and agonist antibodies to activating receptors such as NKp30, NKp44, NKG2D. | 2008-08-21 |
20080199424 | MART-1 T CELL RECEPTORS - T-cell receptors that recognize MART-1 antigen are provided. The TCRs can be used, for example, to treat patients suffering from melanoma. | 2008-08-21 |
20080199425 | Sensitization of Immune System Against Haptenized Melanoma Antigens - The invention is based on the observation that certain phenols, monophenols or benzenediols, can be metabolized into reactive quinones, in particular ortho-quinones and related reactive intermediates, which is brought about by oxidation of monophenols and benzenediols by proteins exhibiting tyrosinase activity, such as human tyrosinase and the related proteins TRP1 and TRP2. Although the substances and the produced reactive intermediates are toxic and can induce cell death, it is more relevant according to this invention that they function as haptens that become covalently bound to the tyrosinase enzymes, in particular to histidine moieties, in or near the catalytic site of proteins exhibiting tyrosinase activity, such as tyrosinase, TRP1 and TRP2. An immune response is then to be mounted against these haptenized auto-antigens, in order to treat melanocytic malignancies, in particular melanomas. This is brought about by topical administration of the phenol compounds that can function as tyrosinase substrate analogues. The invention hence provides medicaments for and methods of treating melanomas. | 2008-08-21 |
20080199426 | Methods and compositions for the treatment and diagnosis of vascular inflammatory disorders or endothelial cell disorders - Disclosed herein are methods for treating a vascular inflammatory disorder or endothelial cell disorder using inhibitor compounds that inhibit the expression or biological activity of Tie-1, Tie-1 endodomain, thrombin, VEGFR2, VEGFR2 endodomain, EphA2, and any of the cytokines or kinases that are upregulated by activation of Tie-1 or thrombin, as provided herein. Also disclosed are the use of combinations of inhibitor compounds or the use of an eNOS activator compound in combination with any one or more of the inhibitor compounds. Also disclosed are methods for inhibiting the pro-coagulant activity of thrombin using a Tie-1 or Tie-1 endodomain inhibitor compound or an EphA2 inhibitor compound. Methods for diagnosing and monitoring vascular inflammatory disorders or endothelial cell disorders that include the measurement of any of the polypeptides or nucleic acid molecules of the invention are also disclosed. | 2008-08-21 |
20080199427 | Novel pyridazine compound and use thereof - A compound of formula (1) and its salts and solvates are provided for the treatment or prophylaxis of hepatitis C virus infections | 2008-08-21 |
20080199428 | Treatment of Liver Diseases in Which Iron Plays a Role in Pathogenesis - The invention relates to the use of 4-[3,5-Bis-(2-hydroxyphenyl)-[1,2,4]-triazol-1-yl]benzoic acid (hereinafter referred to as “Compound I”) for the manufacture of pharmaceutical compositions for the treatment of liver diseases in humans in which iron plays a role in pathogenesis, including viral diseases, such as chronic hepatitis C, optionally in conjunction with antiviral agents and for the treatment of non viral diseases, such as non-alcoholic steatohepatitis and non-alcoholic fatty liver disease. | 2008-08-21 |
20080199429 | Cell Bandage - The invention provides a method for delivering cells across the surface of a tissue, the method comprising distributing the cells on and/or within a sheet of biomaterial to form a cell bandage and applying the cell bandage to the surface, wherein, after application of the cell bandage to the surface of the tissue, the cells are released from the cell bandage. Further provided is a method for bonding two or more tissues, the method comprising providing a cell bandage in intimate contact with the surfaces to be joined, wherein the cell bandage comprises a sheet of biomaterial, said biomaterial having cells distributed on and/or within it. Also provided is a cell bandage for use in the methods of the invention. | 2008-08-21 |
20080199431 | Self-Assembling Membranes And Related Methods Thereof - The present invention relates to self-assembling membranes. In particular, the present invention provides self-assembling membranes configured for securing and/or delivering bioactive agents. In some embodiments, the self-assembling membranes are used in the treatment of diseases, and related methods (e.g., diagnostic methods, research methods, drug screening). | 2008-08-21 |
20080199432 | ROLE FOR SRY IN PARKINSON'S DISEASE - The present invention relates to a method for treating or preventing Parkinson's disease in a patient, the method comprising administering to the patient a therapeutically effective population of neuronal cells transformed with a nucleic acid molecule encoding SRY, wherein the transformed cells express SRY. | 2008-08-21 |
20080199433 | Complementing cell lines - A packaging cell line that complements recombinant adenoviruses based on serotypes from subgroup B, preferably adenovirus type 35. The cell line is preferably derived from primary, diploid human cells that are transformed by adenovirus E1 sequences either operatively linked on one DNA molecule or located on two separate DNA molecules, the sequences being operatively linked to regulatory sequences enabling transcription and translation of encoded proteins. Also disclosed is a cell line derived from PER.C6 that expresses functional Ad35 E1B sequences. The Ad35-E1B sequences are driven by the E1B promoter or a heterologous promoter and terminated by a heterologous poly-adenylation signal. The cell lines are useful for producing recombinant adenoviruses designed for gene therapy and vaccination. The cell lines can also be used for producing human recombinant therapeutic proteins such as human growth factors and human antibodies. Also, the cell lines are useful for producing human viruses other than adenovirus such as influenza virus, herpes simplex virus, rotavirus, and measles virus. | 2008-08-21 |
20080199434 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CARDIOVASCULAR CONDITIONS - The present invention provides methods and compositions for treating a cardiovascular condition. In particular, provided is a method comprising administering to a subject an agent that increases the level and/or activity of angiotensin II type 2 receptors. Also provided is a method for evaluating the risk of having or developing a cardiovascular condition | 2008-08-21 |
20080199435 | IL-8 Like Protein - This present invention relates to a novel protein, termed INSP085, herein identified as an IL-8 like protein and to the use of this protein and nucleic acid sequence from the encoding genes in the diagnosis, prevention and treatment of disease. | 2008-08-21 |
20080199436 | Polypeptides Having Brain-Localizing Activity and Uses Thereof - DNAs encoding polypeptides comprising random amino acid sequences were synthesized, and incorporated into a phage library. The phage library produced was used to screen for polypeptides having brain-localizing activity. As a result, several polypeptides having brain-localizing activity were obtained. These polypeptides comprise common sequences, and amino acid motif sequences involved in brain-localizing activity were successfully identified. | 2008-08-21 |
20080199437 | Lrp4/Corin Dopaminergic Neuron Progenitor Cell Markers - The present invention relates to polynucleotide probes and antibodies for detecting Lrp4/Corin dopaminergic neuron progenitor cell markers, which enable the efficient separation of dopaminergic neuron progenitor cells; and methods for selecting the progenitor cells by the use thereof. | 2008-08-21 |
20080199438 | Methods For Suppressing Tumor Proliferation - The present invention provides methods for suppressing tumor proliferation comprising the step of inhibiting the expression of PDGF-A or the binding between PDGF-A homodimers and PDGFRα. Activation of the PDGFRα-p70S6K signal transduction pathway by PDGF-AA is an important factor in tumor angiogenesis and relates to the prognosis of patients suffering from tumors. By inhibiting PDGF-A expression in tumors or in their surrounding tissues, or by inhibiting the binding between PDGF-A homodimers and PDGFRα, the formation and retention of tumor vasculature can be inhibited, thereby suppressing tumor proliferation. | 2008-08-21 |
20080199439 | IAP-binding cargo molecules and peptidomimetics for use in diagnostic and therapeutic methods - The present invention features peptides, peptidomimetics and methods of their use for binding to Inhibitor of Apoptosis Proteins (IAPs) in cells and prevents the IAP's from exerting their apoptosis-suppressing function with caspases in the cell. An IAP binding cargo molecule having a binding portion mimicking the structural and biological features of the Smac amino-terminal tetrapeptide that is capable of relieving XIAP-mediated suppression of apoptosis in mammalian cells, and a cargo portion with a functional group having a detectable property or therapeutic function is disclosed. | 2008-08-21 |
20080199440 | Tissue Repair Using Allogenic Dermal Fibroblasts - The present invention provides a method for the repair of subcutaneous or dermal tissue in a subject, comprising in one aspect the injection of a suspension of allogeneic dermal fibroblasts into the subject. By injecting a suspension of allogeneic cells, the invention provides, for example, long-term augmentation of the subadjacent tissue without the disadvantages that accompany the preparation and/or use of presently available materials such as autologous fibroblasts cells or collagen. According to a first aspect of the invention there is provided a method for the augmentation of subcutaneous or dermal tissue in a subject, which method comprises the steps of: (i) providing a suspension of allogeneic dermal fibroblasts; and (ii) injecting an effective volume of the suspension into tissue subadjacent to the subcutaneous or dermal tissue so that the tissue is augmented. The method is preferably cosmetic. | 2008-08-21 |