33rd week of 2011 patent applcation highlights part 45 |
Patent application number | Title | Published |
20110201735 | SILOXANE COMPOSITE-BASED LIGHT-WEIGHT OPTICAL LENSES - Disclosed is a process of preparing a moulded article, comprising 1) hydrolysing a) at least one silane having one non-hydrolysable organic group, and b) at least one compound selected from b1) a silane having two non-hydrolysable organic groups, and b2) a hydrolysable polysiloxane, or a mixture thereof, and c) optionally at least one silane having no non-hydrolysable organic group, to prepare a composite composition comprising a hydrolysate or condensate, 2) placing the composite composition in a mould, 3) curing the composite composition to increase the degree of condensation, 4) removing the moulded article from the mould, and 5) heat treating the moulded article at a temperature of at least 100° C. The moulded article is preferably an optical lens which may be used for automobile headlights. | 2011-08-18 |
20110201736 | PRINTABLE FILM - The invention relates to printable films comprising a substrate and at least a surface layer, said layer covering at least one face of said substrate and comprising a water-dispersible polymer and an ethylenically unsaturated compound; to a process for the manufacture of such films; to printed films and especially to printed labels obtained from such printable films. | 2011-08-18 |
20110201737 | POLYVINYL CHLORIDE RESIN COMPOSITIONS AND MANUFACTURING METHOD THEREFOR - A polyvinyl chloride resin composition contains: from 0.005 to 5 parts by weight of a polyvinyl alcohol having a viscosity average degree of polymerization of from 100 to 3000 and having a ratio Mw/Mn of a weight average molecular weight | 2011-08-18 |
20110201738 | Polyolefin Nanocomposites - Disclosed is a polyolefin nanocomposite. The nanocomposite comprises a polyolefin, a quaternary ammonium modified nanoclay, and a Bronsted acid. The polyolefin nanocomposite can have reduced color compared with those which contain polyolefin and quaternary ammonium modified clay but does not contain Bronsted acid. It is useful for making films, pipes, geomembranes, containers, automotive parts, and wire and cable insulations and jackets. | 2011-08-18 |
20110201739 | METHOD AND SYSTEM FOR PRODUCING GRAPHENE AND GRAPHENOL - This disclosure includes a process that unexpectedly can produce very inexpensive graphene and a new compound called graphenol in particulate or dispersions in solvents. The process can also produce graphene layers on metallic and nonmetallic substrates. Further, the graphenol and graphene can be utilized to form nanocomposites that yield property improvements exceeding anything reported previously. | 2011-08-18 |
20110201740 | COATING COMPOSITION WITH ACCELERATED LOW TEMPERATURE CURE - A coating composition including an unsaturated resin selected from polyesters, alkyds or combinations thereof; an alkoxy (meth)acrylic functional monomer, and a thermoplastic compound containing active hydrogen groups; a curing agent; and a curing promoter such as at least one metal drier. | 2011-08-18 |
20110201741 | VINYL CHLORIDE RESIN COMPOSITION FOR TRANSPARENT PRODUCT, AND TRANSPARENT MOLDED PRODUCT PRODUCED BY MOLDING THE COMPOSITION - The vinyl chloride resin composition for transparent products which does not contain heavy metal stabilizers such as lead, tin and barium, characterized in that (A) 0.001˜10 mass parts of at least one kind of organic acid zinc salts and (B) 0.001˜10 mass parts of at least one kind of zinc-modified hydrotalcite compounds are contained relative to 100 mass parts of vinyl chloride resin; and the transparent molded products produced by molding the said composition. | 2011-08-18 |
20110201742 | Halogenated Elastomers with Heat Activated Latent Curative - Mixtures of halogenated elastomers and latent curatives are provided that cure when subjected to sufficient heat to decompose the latent curative. Decomposition products include CO | 2011-08-18 |
20110201743 | Blends of Carbon Blacks and Products Containing the Same - Blends of carbon black or other fillers is described. The blends of carbon black or other fillers are preferably pre-blended prior to introducing the blend into a product such as an elastomeric or polymeric product. | 2011-08-18 |
20110201744 | ACRYLATED EPOXY-AMINE OLIGOMERS - A reactive component suitable for use in a radiation-curable composition, which comprises an acrylated epoxy-amine oligomer represented by the formula (I): C-B-[A-B] | 2011-08-18 |
20110201745 | POLYMER DISPERSION WHICH COMPRISES A HIGHLY BRANCHED POLYCARBONATE HAVING UNSATURATED FATTY ACID GROUPS - The present invention relates to a polymer dispersion which comprises a highly branched polycarbonate having unsaturated fatty acid groups. The invention further relates to highly branched polycarbonates having groups deriving from unsaturated fatty acids, to a process for preparing such highly branched polycarbonates, and to the use of these highly branched polycarbonates for improving the curing properties of coating compositions based on an aqueous acrylate dispersion. | 2011-08-18 |
20110201746 | POLYLACTIC ACID-BASED FILM OR SHEET - A method of producing a polylactic acid based film or sheet with improved heat resistance and comprised of a resin composition containing a polylactic acid according to a melt film forming method, wherein the resin composition comprises polylactic acid (A), an acidic functional group-denatured olefin based polymer (B) containing an acidic functional group, and having an acid number of 10-70 mg KOH/g and a weight average molecular weight of 10,000-80,000, and a tetrafluoroethylene based polymer (C), which method comprises performing melt film formation at a temperature of the resin composition between the crystallization temperature (Tc) in a decreasing temperature process of the resin composition +15° C. and the melting temperature (Tm) in a raising temperature process −5° C., or solidifying the resin composition melt-formed in a film state by cooling after a temperature controllable step at crystallization temperature (Tc) in the decreasing temperature process ±10° C. | 2011-08-18 |
20110201747 | BRANCHED POLYARYLENE ETHERS AND THERMOPLASTIC MOLDING COMPOUNDS CONTAINING SAID ETHERS - The present invention relates to branched polyarylene ethers (A) comprising branching sites of the formula (I): | 2011-08-18 |
20110201748 | CATIONIC POLYMERS CONTAINING 2-HYDROXYALKYL-(METH)ACRYLATES AS PROMOTERS FOR ASA SIZING - The invention relates to polymers useful as a papermaking additives. The invention also relates to methods for making and using such additives. | 2011-08-18 |
20110201749 | PIGMENT AND POLYMERIC MATERIALS DELUSTRED THEREWITH - The invention provides a pigment, the production and use thereof, furthermore a polymeric material delustred with pigments, processes for producing this polymeric material, and the use thereof. | 2011-08-18 |
20110201750 | Modifiers For Nitrile Containing Elastomers - This invention relates to a polymer composition comprising: 70 wt % to 99.5 wt % of a nitrile-group containing elastomer, wherein the elastomer has: a Mooney Viscosity of 15 to 115 MU; and a nitrile monomer content of 0.5 wt % to 50 wt %; and 0.5 wt % to 30 wt % of a non-functionalized plasticizer (NFP), wherein the NFP has: a kinematic viscosity at 100° C. of 4 to 1000 cSt, a flash point of ≧200° C., a viscosity index of ≧120, and a specific gravity of ≦0.865; and wherein the composition has: a 25% compression set at 70 hours and −30° C. that is at least 110% of the 25% compression set of same composition without the NFP tested at the same conditions, and a retained tensile strength, in MPa, after 168 hours at 175° C., that is at least about 88% of the retained tensile strength of the same composition that has not been aged. | 2011-08-18 |
20110201751 | Film Forming Silicone Emulsions - Silicone emulsions are disclosed containing an organosiloxane reaction product from the emulsion polymerization of an alkoxysilane and an epoxy-functional alkoxysilane. The silicone emulsions provide transparent cured films upon drying. | 2011-08-18 |
20110201752 | HIGH IV MELT PHASE POLYESTER POLYMER CATALYZED WITH ANTIMONY CONTAINING COMPOUNDS - A melt phase process for making a polyester polymer melt phase product by adding an antimony containing catalyst to the melt phase, polycondensing the melt containing said catalyst in the melt phase until the It.V. of the melt reaches at least 0.75 dL/g. Polyester polymer melt phase pellets containing antimony residues and having an It.V. of at least 0.75 dL/g are obtained without solid state polymerization. The polyester polymer pellets containing antimony residues and having an It.V. of at least 0.70 dL/g obtained without increasing the molecular weight of the melt phase product by solid state polymerization are fed to an extruder, melted to produce a molten polyester polymer, and extruded through a die to form shaped articles. The melt phase products and articles made thereby have low b* color and/or high L* brightness, and the reaction time to make the melt phase products is short. | 2011-08-18 |
20110201753 | LONG CHAIN BRANCHED (LCB), BLOCK OR INTERCONNECTED COPOLYMERS OF ETHYLENE IN COMBINATION WITH ONE OTHER POLYMER - An ethylenic polymer comprising amyl groups from about 0.1 to about 2.0 units per 1000 carbon atoms as determined by Nuclear Magnetic Resonance and both a peak melting temperature, T | 2011-08-18 |
20110201754 | High-Molecular Weight Conjugate Of Physiologically Active Substances - Disclosed is a water-soluble high-molecular weight conjugate of physiologically active substances which enable medicament to release without depending on the enzymes in a living body and which is expected to have a useful therapeutic effect. A high-molecular weight conjugate of a physiologically active substance has a substituent group represented by a general formula (1) bonded to a side-chain carboxy group of a block copolymer which has a polyethylene glycol moiety and either a polyaspartic acid moiety or a polyglutamic acid moiety. Formula (1): —Ar—CR15R16-O—C(═O)-A [In the formula: Ar represents an aromatic hydrocarbon group optionally a substituent group, or an aromatic heterocyclic group optionally having a substituent group; R15 and R16 independently represent a hydrogen atom or a (C1-C6) alkyl group optionally having a substituent group; and A represents a residual group of a physiologically active substance that has an carboxy group, or a residual group of a physiologically active substance that has an amino group]. | 2011-08-18 |
20110201755 | THERMOPLASTIC NANOCOMPOSITE MATERIAL BASED ON NANOCRYSTALLINE CELLULOSE (NCC) - A green approach for the development of nanocomposite materials comprising nanocrystalline cellulose (NCC) and appropriate vinyl polymers is conceived. The approach deals with the in-situ graft co-polymerization of hydrophobic vinyl monomers, such as vinyl acetate and methyl methacrylate, onto the NCC surface in an aqueous medium. The resulting material is significantly more hydrophobic and thermally stable than the starting NCC. The nanocomposite material can be suspended in appropriate solvents, dried and moulded with other materials using conventional polymer processing techniques to develop yet new materials with new characteristics. These nanocomposites have wide ranging applications from industrial to medical use. | 2011-08-18 |
20110201756 | NOVEL AMPHIPHILIC BLOCK COPOLYMER, METHOD FOR MANUFACTURING THE SAME, AND POLYMER ELECTROLYTE MEMBRANE USING THE SAME - The present invention provides an amphiphilic block copolymer, a method for manufacturing the same, and a fuel cell membrane using the same. According to preferred embodiments, the amphiphilic block copolymer may contain poly(arylene sulfone ether ketone) (PSEK) as a hydrophobic component and poly(sulfonated styrene-co-acrylonitrile) (PSSAN) as a hydrophilic component. According to other preferred embodiments, polymer electrolyte membrane manufactured using the amphiphilic block copolymer has certain advantages in that the hydrogen ion conductivity is not reduced even at a high temperature of more than 100° C. but is rather increased and the thermal and chemical dimensional stability is excellent. | 2011-08-18 |
20110201757 | Methods for Production of High Impact Polystyrene - A method of preparing a high impact polystyrene comprising contacting styrene monomer, a high cis polybutadiene elastomer, and an initiator under high shear within a reaction zone. A high-impact polystyrene comprising a high cis polybutadiene elastomer. A method of preparing a high impact polystyrene comprising contacting styrene monomer, a high cis polybutadiene elastomer, and an initiator under extreme reaction conditions within a reaction zone. | 2011-08-18 |
20110201758 | Tough composition for food applications - Heterophasic polypropylene composition comprising:—a polypropylene matrix (M) and—an elastomeric copolymer (E) being dispersed in the matrix (M), wherein the elastomeric copolymer (E) comprises units derived from—propylene and—ethylene and/or C4 to C20 α-olefin, and wherein further,—the intrinsic viscosity of the xylene cold soluble fraction (XCS) of the heterophasic polypropylene composition is above 2.1 dl/g measured according to ISO 1628-1 (at 135° C. in decaline) and/or—Mz/Mw of the xylene cold soluble fraction (XCS) of the heterophasic polypropylene composition is more than 2.6, preferably 2.7, wherein the Mz is the z-average molecular weight measured according to ISO 16014-4:2003 and Mw is the weight average molecular weight measured according to ISO 16014-4:2003. | 2011-08-18 |
20110201759 | ONIUM SALT-CONTAINING POLYMER - It is to provide a polymer having a high antistatic function, a high solubility to solvent and high compatibility to a formulation, and an antistatic agent, curable composition or a water repellent and oil repellent comprising the polymer. It is a linear block polymer, block star polymer or block graft polymer in which at least one block is a block wherein an anion and a counter cation form an onium salt on the polymer chain side, and a composition comprising the same. It is preferred that a linear block polymer has a number average molecular weight of 20000 or less, and a block star polymer and block graft polymer has a number average molecular weight of 10000 or more. | 2011-08-18 |
20110201760 | Method of Drying A Material Having A Cohesive Phase - A method for drying a material such as a polymer hydrogel which passes through a cohesive phase as it dries is disclosed. The method comprises agitating a composition while removing liquid until the solids content of the composition reaches a level at which the composition enters a cohesive phase, halting agitation, removing liquid from the composition in the absence of agitation, and resuming agitation. Practice of the present invention can eliminate the problems associated with adhesion of a material to itself and to process equipment during the cohesive phase. | 2011-08-18 |
20110201761 | AMPHIPHILIC BLOCK COPOLYMERS - The invention relates to novel crosslinkable copolymers of formula | 2011-08-18 |
20110201762 | POLYCARBONATE RESIN COMPOSITION AND OPTICAL MATERIALS USING THE SAME - To provide a polycarbonate resin composition excellent in low-birefringence and environment resistance properties to be used for optical materials such as lenses, films or sheets. | 2011-08-18 |
20110201763 | THERMOSETTING RESIN COMPOSITION FOR OPTICAL-SEMICONDUCTOR ELEMENT ENCAPSULATION AND CURED MATERIAL THEREOF, AND OPTICAL-SEMICONDUCTOR DEVICE OBTAINED USING THE SAME - The present invention relates to a thermosetting resin composition for optical-semiconductor element encapsulation, the thermosetting resin composition including the following ingredients (A) to (D): (A) an epoxy group-containing siloxane compound represented by the following general formula (1) in which R | 2011-08-18 |
20110201764 | POLYMER/CARBON-NANOTUBE INTERPENETRATING NETWORKS AND PROCESS FOR MAKING SAME - The present invention is directed to new methods for combining, processing, and modifying existing materials, resulting in novel products with enhanced mechanical, electrical and electronic properties. The present invention provides for polymer/carbon nanotube composites with increased strength and toughness; beneficial for lighter and/or stronger structural components for terrestrial and aerospace applications, electrically and thermally conductive polymer composites, and electrostatic dissipative materials. Such composites rely on a molecular interpenetration between entangled single-wall carbon nanotubes (SWNTs) and cross-linked polymers to a degree not possible with previous processes. | 2011-08-18 |
20110201765 | METHOD AND APPARATUS FOR MANAGING VOLATILE ORGANIC CONTENT IN POLYOLEFIN - The present invention relates generally to polyolefin production and to reducing volatile organic content (VOC) associated with the polyolefin. Techniques include the construction and implementation of a purge column model to calculate or estimate the VOC content in the polyolefin exiting the purge column. The techniques facilitate the design and operation of the polyolefin manufacturing process. | 2011-08-18 |
20110201766 | Method and System to Add High Shear to Improve an Ionic Liquid Catalyzed Chemical Reaction - In an embodiment, a method is disclosed to increase the activity of an ionic liquid catalyst comprising emulsifying the ionic liquid catalyst with one or more liquid components. In an embodiment, a method is disclosed comprising introducing into a reaction zone a monomer feed and a reduced amount of ionic liquid catalyst and controlling an amount of shear present in the reaction zone to maintain a desired conversion reaction of the monomer. In an embodiment, a catalyzed reaction system is disclosed comprising a reactor configured to receive one or more liquid components and ionic liquid catalyst; a device coupled to the reactor for adding high shear to the liquid components and ionic liquid catalyst; and a controller coupled to the device for adding high shear and configured to control the amount of shear added to a catalyzed reaction zone to maintain a conversion reaction. | 2011-08-18 |
20110201767 | PROCESS FOR PREPARING POLYMERS FROM 3-METHYLBUT-1-ENE - The present invention relates to a copolymer which contains 3-methylbut-1-ene as a comonomer and which contains ethene or propene as a further monomer, the proportion of the incorporated 3-methylbut-1-ene being 0.1 to 40 mol %, and to a process for preparing such copolymers, the polymerization being performed in the presence of a catalyst which comprises at least one cyclopentadienyl group. | 2011-08-18 |
20110201768 | SYSTEM AND METHOD FOR CATALYST ACTIVATION - A system and method for activating chromium catalyst, including: increasing temperature of a chromium catalyst at a first rate for a first period of time to a first temperature; and increasing temperature of the chromium catalyst at a second rate for a second period of time from the first temperature to a second temperature, wherein the first rate is greater than the second rate, and wherein the first period precedes the second period. | 2011-08-18 |
20110201769 | Copolymers Of Ethylene And At Least One Other 1-Olefin, And Process For Their Preparation - Ethylene copolymers composed of ethylene units and units composed of at least one other 1-olefin whose density is from 0.940 to 0.955 g/cm | 2011-08-18 |
20110201770 | DUAL METALLOCENE CATALYSTS FOR POLYMERIZATION OF BIMODAL POLYMERS - This invention relates to catalyst compositions, methods, and polymers encompassing at least one first Group 4 metallocene compound comprising bridging η | 2011-08-18 |
20110201771 | BIOSYNTHESIS OF POLYISOPRENOIDS - The synthetic production of cis-1,4-polyisoprene and other cis-1,4-polydienes is achieved by adding isoprene or other diene monomers to a natural rubber latex or washed rubber particles and utilizing various allylic pyrophosphate compounds. The natural rubber latex or washed rubber particles inherently contain an enzyme catalyst and desirably divalent metal cofactors therein and the polymerization can occur over a relatively wide temperature range. The process is believed to be a living carbocationic polymerization. The in vitro produced natural rubber polymers can contain from about 5 to about 30,000 repeat units and are essentially free of non-enzyme catalysts. The invention can be utilized to synthesize polyisoprenoids and precursors to form terpenes, vitamins, steroids, alkaloids, and the like. | 2011-08-18 |
20110201772 | PROCESS FOR PREPARING HIGH-REACTIVITY ISOBUTENE HOMO- OR COPOLYMERS - Preparation of high-reactivity isobutene homo- or copolymers with a content of terminal vinylidene double bonds per polyisobutene chain end of at least 50 mol % and a polydispersity of preferably 1.05 to less than 3.5, by polymerizing isobutene or an isobutene-comprising monomer mixture in the presence of an aluminum trihalide-donor complex effective as a polymerization catalyst or of an alkylaluminum halide-donor complex, especially of an aluminum trichloride-donor complex, said complex comprising, as the donor, an organic compound with at least one ether function or a carboxylic ester function. | 2011-08-18 |
20110201773 | POLYMER-DENDRIMER HYBRIDS - The present invention relates to a branched vinyl polymer carrying dendrons made from monofunctional vinyl monomers and branched by virtue of difunctional vinyl monomers so that there is on average one branch or fewer per polymer chain to avoid gelation. The polymer may be made by chain-growth polymerization of predominantly monofunctional vinyl monomers in the presence of difunctional vinyl monomers and dendron units. | 2011-08-18 |
20110201774 | FLUOROPOLYMER AND COMPOSITION THEREOF - The present invention provides a fluoropolymer capable of giving fluorine-containing molded materials and laminates excellent in moldability, productivity, interlaminar bonding and stress cracking resistance, in particular stress cracking resistance upon contacting with various liquid chemicals, without impairing such characteristics intrinsic in fluororesins as chemical resistance, solvent resistance, weathering resistance, antifouling properties, liquid chemical impermeability and nonstickiness. The present invention provides a fluoropolymer which is an oligomer-containing or oligomer-free fluoropolymer, wherein said oligomer has a molecular weight not higher than 10,000 and amounts to not more than 0.05% by mass relative to the fluoropolymer. | 2011-08-18 |
20110201775 | High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) - The presence of certain impurities in diphenyl sulfone have a deleterious effect on the properties of the poly(aryletherketone)s produced therein, including one or more of color, melt stability, molecular weight, crystallinity, etc. and here identify those impurities and provide processes for the removal of such impurities. | 2011-08-18 |
20110201776 | Method for Thermally Treating Polyester Pellets to Obtain a Partial Crystallization - The invention relates to a method for thermally treating polyester pellets to obtain partial crystallization, whereby the polyester melt is supplied to an underwater granulating system and granulated; the thus obtained granulate are fed from the underwater granulating system into a water-solids separator. The dried granulate is then fed into a treatment device at a granulate temperature higher than 100 degrees C., without external energy or heat being supplied. The intrinsic heat of the granulate is used as the heat treatment leading to partial crystallization. The crystallization device is embodied as an at least lightly inclined reactor, into which granulate is fed at a temperature higher than 100 degrees C. The granulate passes through the reactor from the loading point to the discharge point under its own weight and exits the reactor with a temperature higher than 130 degrees C. | 2011-08-18 |
20110201777 | PI-ELECTRON CONJUGATED COMPOUND, MANUFACTURING METHOD THEREFOR, AND PI-ELECTRON CONJUGATED POLYMER OBTAINED USING SAME - Provided are a π-electron conjugated polymer having a constitutional unit represented by general formula (2) that is suitable as an electrochromic material that changes from a desired colored state to a decolored state, a new compound that is a raw material of the polymer, and a method for producing the polymer: wherein each X independently represents one selected from the group consisting of an oxygen atom, a sulfur atom, —NH—, and —NR | 2011-08-18 |
20110201778 | Organic Electroluminescent Devices - The present invention relates to electronic devices, in particular organic electroluminescent devices, which comprise compounds of the formula (1), and to the corresponding compounds and to the use thereof in organic electroluminescent devices. | 2011-08-18 |
20110201779 | PURIFICATION OF POLYCARBONATES - The present disclosure provides, in part, a method for removing a catalyst from a product of catalyzed aliphatic polycarbonate polymerization reaction. | 2011-08-18 |
20110201780 | NOVEL DEATH DOMAIN PROTEINS - In accordance with the present invention, there are provided novel Death Domain (DD), Death Effector Domain (DED) and NB-ARC domain proteins. The invention also provides nucleic acid molecules encoding DD, DED and NB-ARC domain proteins, vectors containing these nucleic acid molecules and host cells containing the vectors. The invention also provides antibodies that can specifically bind to invention DDs, DEDs or NB-ARC domains. Such DDs, DEDs and NB-ARC domains and/or anti-DD, anti-DED or anti-NB-ARC domain antibodies are useful for discovery of drugs that suppress infection, autoimmunity, inflammation, allergy, allograft rejection, sepsis, and other diseases. | 2011-08-18 |
20110201781 | CYSTEINE LABELING SYSTEM AND METHOD OF USE THEREOF - A method of use of a cysteine labeling system includes: providing a 2-cyano benzothial core with a covalently-linked biomolecule X in a reaction environment; and reacting the 2-cyano benzothial core to an N-terminal cystenine. | 2011-08-18 |
20110201782 | NOVEL HUMAN GENES RELATING TO RESPIRATORY DISEASES AND OBESITY - This invention relates to isolated nucleic acids comprising genes of human chromosome 12q23-qter and the proteins encoded by these genes. Expression vectors and host cells containing such genes or fragments thereof, as well as antibodies to the proteins encoded by these nucleic acids are also included herein. | 2011-08-18 |
20110201783 | Apparatus for the Preparation of a Thread From Silk Proteins - The present invention relates to a thread preparation process from silk proteins including an apparatus which is appropriate for performing the method. Furthermore, the invention is directed to the threads obtained therewith as well as the use thereof. The invention uses a diffusion unit leading to the production of high-quality silk threads with high yield. | 2011-08-18 |
20110201784 | FUNCTIONALIZED CYANINE HAVING A SILANE LINKER ARM, A METHOD OF PREPARING THEREOF AND USES THEREOF - A silane-modified cyanine of Formula (I) includes the valence tautomers thereof: wherein R | 2011-08-18 |
20110201785 | METHOD FOR OPTIMIZING PROTEINS HAVING THE FOLDING PATTERN OF IMMUNOGLOBULIN - The invention relates to a method for optimizing the biophysical properties of molecules and derivatives of the Ig superfamily. The method is characterized in that as yet unrecognized helical structural elements with unknown structural, stability and folding roles have been identified as important determinants of correct and efficient structuring of antibody domains. The novel process for positively influencing the antibody properties and properties of other proteins that have the Ig folding pattern now consists of optimizing the properties of the short helical elements and in the transplantation of these elements between Ig domains. | 2011-08-18 |
20110201786 | HYBRIDOMA PRODUCING ANTIBODIES TO LAWSONIA INTRACELLULARIS - The present invention relates to the field of animal health and in particular to | 2011-08-18 |
20110201787 | HYBRIDOMA PRODUCING ANTIBODIES TO LAWSONIA INTRACELLULARIS - The present invention relates to the field of animal health and in particular to | 2011-08-18 |
20110201788 | HYBRIDOMA PRODUCING ANTIBODIES TO LAWSONIA INTRACELLULARIS - The present invention relates to the field of animal health and in particular to | 2011-08-18 |
20110201789 | ANTIBODIES TO LAWSONIA INTRACELLULARIS - The present invention relates to the field of animal health and in particular to | 2011-08-18 |
20110201790 | HYBRIDOMA PRODUCING ANTIBODIES TO LAWSONIA INTRACELLULARIS - The present invention relates to the field of animal health and in particular to | 2011-08-18 |
20110201791 | MULTIVALENT PNEUMOCOCCAL POLYSACCHARIDE-PROTEIN CONJUGATE COMPOSITION - An immunogenic composition having 13 distinct polysaccharide-protein conjugates and optionally, an aluminum-based adjuvant, is described. Each conjugate contains a capsular polysaccharide prepared from a different serotype of | 2011-08-18 |
20110201792 | SYNTHESIS OF AZO BONDED IMMUNOREGULATORY COMPOUNDS - Methods are disclosed for preparing compounds of Formula I: | 2011-08-18 |
20110201793 | PROCESS FOR PRODUCTION OF GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVE - The present invention relates to a method for preparing the glucopyranosyloxypyrazole derivatives which are useful as agents for the prevention or treatment of a disease associated with hyperglycemia such as diabetes, diabetic complications, obesity or the like. | 2011-08-18 |
20110201794 | Disaccharides for drug discovery - Methods are described for the preparation of combinatorial libraries of potentially biologically active disaccharide compounds. These compounds are variously functionalized, with a view to varying lipid solubility size, function an other properties, with the particular aim of discovering novel drug or drug-like compounds, or compounds with useful properties. The invention provides intermediates, processes and synthetic strategies for the solution or solid phase synthesis of disaccharides, variously functionalized about the sugar ring, including the addition of aromaticity and charge, and the placement of pharmaceutically useful groups and isosteres. | 2011-08-18 |
20110201795 | Methods of Producing C-Aryl Glucoside SGLT2 Inhibitors - Method for the production of C-aryl glucoside SGLT2 inhibitors useful for the treatment of diabetes and related diseases. and intermediates thereof. The C-aryl glucosides may be complexed with amino acid complex forming reagents. | 2011-08-18 |
20110201796 | DNA sequence in plant caragana jubata with freeze tolerance - An isolated DNA sequence set forth in SEQ ID NO: 32, which is differentially expressed in apical buds of plant | 2011-08-18 |
20110201797 | Nucleic Acid Shearing Device with Disposable Cartridge - Apparatus, devices, and methods for shearing nucleic acids are provided. In one exemplary embodiment the device is a disposable nucleic acid shearing cartridge. The cartridge includes two reservoirs, an orifice structure disposed therebetween, and a fluid driver. The reservoirs are in fluid communication with each other by way of the orifice structure, and the fluid driver cycles a sample between the two reservoirs. By passing a sample from one reservoir to the next, through the orifice structure, an orifice located in the orifice structure can shear the sample to a desired length. The sheared sample can then be used, for example, in a sequencing device. Apparatuses for cycling samples in the cartridge, and methods and kits for shearing nucleic acids, are also disclosed. | 2011-08-18 |
20110201798 | THERAPEUTIC COMPOSITIONS - This application relates to therapeutic siRNA agents and methods of making and using the agents. | 2011-08-18 |
20110201799 | Synthesis of oligonucleotides - A method for preparing an oligonucleotide comprising the steps of a) providing a hydroxyl containing compound having formula (1), wherein B is a heterocyclic base, and radicals R | 2011-08-18 |
20110201800 | AZACITIDINE PROCESS AND POLYMORPHS - Processes for preparing azacitidine. Further included are processes for the preparation of crystalline azacitidine crystalline Form (I) and mixtures of azacitidine crystalline Forms (I) and (II). | 2011-08-18 |
20110201801 | SACCHARIDE STRUCTURES AND METHODS OF MAKING AND USING SUCH STRUCTURES - Described are oligosaccharides having a protecting group at two, a plurality, a majority of, or each position in the oligosaccharide which is amenable to derivatization. Collections, libraries and methods of making and using such oligosaccharides are also described. | 2011-08-18 |
20110201802 | Novel Compound and Functional Luminescent Probe Comprising the Same - Disclosed is a compound characterized by comprising a linker, an oxygen-concentration-responsive phosphorophore which is linked to a first end of the linker, and a fluorophore which is lined to a second end of the linker. In the compound, it is preferred that the triplet level of the phosphorophore be lower than that of the fluorophore. The compound can be used as an oxygen-responsive luminescent probe. | 2011-08-18 |
20110201803 | PYRROLOBENZODIAZEPINES - The invention relates to certain pyrrolobenzodiazepines (PBDs), and in particular pyrrolobenzodiazepine dimers bearing C2 substitutions, including compounds of formula (T): wherein: R | 2011-08-18 |
20110201804 | PROCESS FOR THE PREPARATION OF 1- ( 3-HYDROXYMETHYLPYRID-2 -YL ) -2 -PHENYL-4-METHYLPIPERAZINE AND MIRTAZAPINE - Disclosed herein is a process for the manufacture of mirtazapine and intermediates useful in preparing mirtazapine which includes the reduction of 1-(3-carboxypyridyl-2)-4-methyl-2-phenylpiperazine with an organoaluminum hydride. | 2011-08-18 |
20110201805 | Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid - Process for the synthesis of ivabradine of formula (I): | 2011-08-18 |
20110201806 | Methods for Forming Protected Organoboronic Acids - Described are methods of forming protected boronic acids that provide in a manner that is straightforward, scalable, and cost-effective a wide variety of building blocks, such as building blocks containing complex and/or pharmaceutically important structures, and/or provide simple or complex protected organoboronic acid building blocks. A first method includes reacting an imino-di-carboxylic acid and an organoboronate salt. A second method includes reacting a N-substituted morpholine dione and an organoboronic acid. | 2011-08-18 |
20110201807 | 3-HYDRAZINO-2,5-DIOXOPYRROLIDINE-3-CARBOXYLATE, PROCESS FOR PRODUCTION OF THE SAME, AND USE OF THE SAME - The present invention provides 3-hydrazino-2,5-dioxopyrrolidine-3-carboxylates of the formula (I): | 2011-08-18 |
20110201808 | NOVEL COMPOUND HAVING AFFINITY TO AMYLOID - The invention relates to a compound which has affinity with amyloid, shows sufficiently rapid clearance from normal tissues and is suppressed in toxicity such as mutagenicity, and also relates to a low-toxic diagnostic agent for Alzheimer's disease containing the compound. The compound is represented by the following formula (1) or a salt thereof: | 2011-08-18 |
20110201809 | Process for Preparing Entecavir and its Intermediates - A process of making entecavir comprising converting a compound of formula (M5) | 2011-08-18 |
20110201810 | Method for Preparing 4-[9-(6-Aminopurine)]-2-(S)-Hydroxyl-Butyric Acid Methyl Ester - The present invention discloses a novel method for preparing and purifying 4-(6-Amino-purin-9-yl)-2(S)-hydroxy-butyric acid methyl ester. The preparation started from cheap and easily available L-malic acid, which was transformed to intermediate I after simultaneous protection of the groups of 1-carboxyl and 2-hydroxyl. The intermediate I was selectively reduced to intermediate alcohol II, whose hydroxyl group was further transformed to an easily leaving group to afford intermediate III. The intermediate III was nucleophilically substituted with adenine to afford intermediate IV. The intermediate IV was deprotected and methyl-esterified simultaneously in methanol in the presence of an acid or a base to afford crude 4-(6-Amino-purin-9-yl)-2(S)-hydroxy-butyric acid methyl ester, which was purified by recrystallization to afford the purified product. Comparing with the prior preparation methods, the present method has advantages in low cost, mild conditions, high retention of the chiral center during the reaction, high productivity, great improvement in the quality and yield of the product and great decrease in cost, and thus is suitable for the production on a large scale. | 2011-08-18 |
20110201811 | DIHYDROPYRIDINE CALCIUM ANTAGONIST COMPOUNDS, PREPARATION METHODS, AND MEDICAL USES THEREOF - A dihydropyridine (DHP) calcium antagonist compound and its preparation method and medical use are related to preparation methods of compounds of general formulas (I) and (II) as shown below and their pharmaceutical salts and applications for treating cardiovascular diseases, and R | 2011-08-18 |
20110201812 | PROCESS FOR THE MANUFACTURE OF AN INDOLINONE DERIVATIVE - The present invention relates to a process for the manufacture of a specific indolinone derivative and a pharmaceutically acceptable salt thereof, namely 3-Z-[1-(4-(N-((4-methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone and its monoethanesulfonate, to new manufacturing steps and to new intermediates of this process. | 2011-08-18 |
20110201813 | Catalyst Components Based on Ferricinium Complexes Used for Olefin Polymerization - The present invention discloses catalyst components based on ferricinium ligands, their method of preparation and their use in the polymerisation of olefins. | 2011-08-18 |
20110201814 | METHOD FOR PRODUCING SOLID PREPARATION - A method for producing a solid preparation containing a compound represented by the formula (I) below or a pharmacologically acceptable salt thereof, which comprises a step wherein a composition containing the compound represented by the general formula (I) below or a pharmacologically acceptable salt thereof is mixed, while applying mechanical stress to the composition. The compound of the formula (I) is as follows: | 2011-08-18 |
20110201815 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES - The present invention provides compounds useful as agents for the prevention or treatment of a disease associated with abnormal plasma uric acid level and the like. The present invention relates to fused heterocyclic derivatives represented by the following formula (I) having xanthine oxidase inhibitory activities and useful as agents for the prevention or treatment of a disease associated with abnormality of plasma uric acid level, prodrugs thereof, salts thereof or the like. In the formula (I), T represents trifluoromethyl, nitro or cyano; ring Q represents heteroaryl; X | 2011-08-18 |
20110201816 | METHODS OF SCREENING FOR COMPOUNDS THAT INHIBIT THE BIOSYNTHESIS OF GPI IN MALARIA PARASITES - The present inventors succeeded in isolating GWT1 (PfGWT1), which is one of the enzymes involved in GPI biosynthesis in the malaria parasite | 2011-08-18 |
20110201817 | LEVODOPA PRODRUGS, AND COMPOSITIONS AND USES THEREOF - Prodrugs of levodopa, methods of making prodrugs of levodopa, methods of using prodrugs of levodopa, and compositions of prodrugs of levodopa are disclosed. | 2011-08-18 |
20110201818 | POLO-LIKE KINASE INHIBITORS - Compounds of the following formula are provided for use with kinases: | 2011-08-18 |
20110201819 | METHOD FOR PRODUCING ALCOHOL COMPOUND - Disclosed is a practical method for efficiently producing an alcohol compound by hydrogenating an aldehyde by using a homogeneous copper catalyst which is an easily-available low-cost metal species. Specifically disclosed is a method for producing an alcohol compound, which is characterized in that a hydrogenation reaction of an aldehyde compound is performed in the presence of a homogeneous copper catalyst and a diphosphine compound. | 2011-08-18 |
20110201820 | METHOD FOR PRODUCING ALCOHOL COMPOUND - Disclosed is a practical method for efficiently producing an alcohol compound by hydrogenating an aldehyde by using a homogeneous copper catalyst which is an easily-available low-cost metal species. Specifically disclosed is a method for producing an alcohol compound, which is characterized in that a hydrogenation reaction of an aldehyde compound is performed in the presence of a homogeneous copper catalyst, a monophosphine compound and an alcohol selected from the group consisting of primary alcohols, secondary alcohols and mixtures of those. | 2011-08-18 |
20110201821 | NEW PROCESS FOR THE PREPARATION OF 2-IMINO-THIAZOLIDIN-4-ONE DERIVATES - The present invention relates to a new process for the preparation of 2-imino-thiazolidin-4-one compounds of the Formula (I) and (II) and to compounds of Formula (II) as such. The present compounds of Formula (II) can be used as intermediates in the preparation of thiazolidin-4-one derivatives of the General Formula (II), said derivatives being described in WO 2005/054215. These compounds of General Formula (II) are described in WO 2005/054215 to act as immunosuppressive agents. | 2011-08-18 |
20110201822 | METHODS FOR PRODUCTION OF 1,2,4-TRIAZOL-3-ONE - Novel methods for producing 1,2,4-triazol-3-one from semicarbazide hydrochloride and formic acid are provided. In methods of this invention, water is used in removal of unreacted formic acid to increase yield and purity of produced 1,2,4-triazol-3-one. | 2011-08-18 |
20110201823 | SALT AND PROCESS FOR PRODUCING ACID GENERATOR - A salt represented by the formula (I0): | 2011-08-18 |
20110201824 | BIODEGRADABLE SOLVENTS FOR THE CHEMICAL INDUSTRY - This invention relates to ionic liquid (ILs) solvents for chemical synthesis based on an alkyl-imidazolium cation core containing ionic liquids which have enhanced biodegradability and reduced toxicity relative to existing imidazolium bases ILs such as 1-butyl-3-methylimidazolium (bmmim) salts. Many of the described ILs produce a score of over 60% biodegradability over 28 days in a biodegradability test such as the Sturm Test, the Closed Bottle Test (OECD 301D) or the CO | 2011-08-18 |
20110201825 | Method for Producing Fluorosulfuric Acid Ester - Fluorosulfuric acid esters can be produced by reacting alcohols with sulfuryl fluoride (SO | 2011-08-18 |
20110201826 | CONJUGATED POLYMERS FROM SUBSTITUTED 3,4-PROPYLENEDIOXYTHIOPHENE, COMPOSITIONS, METHOD OF MAKING, AND USE THEREOF - Polymers and copolymers having units derived from substituted 3,4-propylenedioxythiophene are disclosed. Also provided are methods of making and using the same. | 2011-08-18 |
20110201827 | PROCESS FOR CONTINUOUS PRODUCTION OF OXIDIZED OLEFIN POLYHEDRAL OLIGOMERIC SILSESQUIOXANE CAGES - Methods for continuous bulk production of polyolefin polyhedral oligomeric silsesquioxanes and their amino, isocyanate, and alcohol derivatives using silane coupling agents as precursors. | 2011-08-18 |
20110201828 | METHOD AND CATALYSTS FOR PRODUCING CYCLIC CARBONATES - Process for the preparation of cyclic carbonates by reacting a polyhydric alcohol with a dialkyl carbonate in the presence of a heterogeneous catalyst, wherein the heterogeneous catalyst is a basic mixed oxide or a basic oxide applied to a support. | 2011-08-18 |
20110201829 | MODIFIED TRILOBE SHAPE FOR MALEIC ANHYDRIDE CATALYST - Embodiments of the present invention include improved shaped catalyst structures containing catalytic material comprised of mixed oxides of vanadium and phosphorus and using such shaped catalyst structures for the production of maleic anhydride. | 2011-08-18 |
20110201830 | HIGH PORE VOLUME VPO CATALYST FOR MALEIC ANHYDRIDE PRODUCTION - Embodiments of the present invention disclose improved micro-pore catalyst structures containing catalytic material comprised of mixed oxides of vanadium and phosphorus and using such improved micro-pore catalyst structures for the production of maleic anhydride. | 2011-08-18 |
20110201831 | PROCESS FOR PREPARING NEBIVOLOL - The present invention relates to a process for preparing nebivolol and, more particularly, to a process for preparing d-nebivolol and its enantiomer l-nebivolol or acid addition salts thereof starting from commercially available or easily obtainable 2,2-dimethyl-1,3 dioxolane-4-carbaldehyde and a vinyl Grignard reagent. | 2011-08-18 |
20110201832 | VAPOR-PHASE DECARBONYLATION PROCESS - A process is provided for the synthesis of furan and related compounds by vapor phase decarbonylation of furfural and derivatives, using a palladium/alumina catalyst that has been promoted with an alkali carbonate. Catalyst lifetime is improved. The catalyst can be regenerated in situ by feeding a mixture of air and steam, with a composition of between about 2% and about 40% air, to the catalyst bed at a temperature between about 300° C. and about 500° C. | 2011-08-18 |
20110201833 | POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH HIGH COMONOMER INCORPORATION - The present techniques relate to catalyst compositions, methods, and polymers encompassing a Group 4 metallocene compound comprising bridged η | 2011-08-18 |
20110201834 | Scaffold Materials-Transition Metal Hydride Complexes, Intermediates Therefor and Method for Preparing the Same - The present invention relates to substances which can be applied to the technical fields of gas storages, polymerization catalysts and optical isomers, their intermediates, and processes for preparing the same, which is characterized in that 1) possible disintegration of structure of the scaffold material (SM) is impeded, and 2) they are prepared by a simple manufacturing system as compared to the substances conventionally suggested in the application field. Specifically, it relates to scaffold material-transition metal hydride complexes comprised of scaffold material (SM) and transition metal hydride (M | 2011-08-18 |