| 31st week of 2012 patent applcation highlights part 37 |
| Patent application number | Title | Published |
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| 20120195932 | Geodate delivery vehicles - The present invention provides geodate delivery vehicles and methods of manufacture and administration. A vehicle including a lipid monolayer disposed about a hydrophobic domain is disclosed, that can be part of an emulsion or other mixture, or further disposed in a lipid strata. A vehicle including a lipid strata disposed about a hydrophobic domain is also disclosed. The vehicle can be incorporated into a variety of medicinal, food preparations, and personal care products to deliver or stabilize a cargo moiety. Packaged delivery vehicles for to later addition of cargo moieties are also contemplated. | 2012-08-02 |
| 20120195933 | PHARMACEUTICAL COMPOSITIONS COMPRISING TASOCITINIB - The invention relates to pharmaceutical compositions, preferably tablets, comprising tasocitinib, suitable for immediate release, and processes of preparing such compositions. | 2012-08-02 |
| 20120195934 | POLYMERIC GEL DELIVERY SYSTEM FOR PHARMACEUTICALS - Implantable, injectable, insertable, or otherwise administrable compositions that form hydrogels when implanted, injected, inserted, or administered into or onto living tissues comprise a pharmaceutically effective compound wherein the pharmaceutically effective compound is a codrug, or pharmaceutically acceptable salt or prodrug thereof in admixture with a hydrogel-forming compound. The pharmaceutically effective compound may be any compound that is soluble in bodily fluids, or that forms bodily fluid-soluble adducts when exposed to bodily fluids. Exemplary compounds include analgesic, anti-inflammatory and antibiotic compounds. The hydrogel-forming compound is a biologically tolerated substance that forms a hydrogel upon exposure to bodily fluids, such as the interstitial fluid surrounding or within a joint. | 2012-08-02 |
| 20120195935 | MICROBUBBLE ASSISTED VIRAL DELIVERY - Microbubble-assisted delivery of viruses is disclosed. In particular, methods for targeting a virus to cancer cells in an immunocompetent animal by administering a selectively replicating virus to the immunocompetent animal and disrupting the microbubbles in a location of the animal comprising cancer cells are provided. The virus is encompassed in a suspension of microbubbles, and the surface of the suspension does not include any virus. A suspension of microbubbles comprising a selectively replicating virus that is encompassed in a suspension of microbubbles, which does not include any virus on the surface of the suspension, is also provided. | 2012-08-02 |
| 20120195936 | RNA WITH A COMBINATION OF UNMODIFIED AND MODIFIED NUCLEOTIDES FOR PROTEIN EXPRESSION - The invention relates to a polyribonucleotide with a sequence that codes a protein or protein fragment, wherein the polyribonucleotide comprises a combination of unmodified and modified nucleotides, wherein 5 to 50% of the uridine nucleotides and 5 to 50% of the cytidin nucleotides are modified uridine nucleotides or modified cytidin nucleotides. | 2012-08-02 |
| 20120195937 | POLYANIONIC POLYMER ADJUVANTS FOR HAEMOPHILUS INFLUENZAE B SACCHARIDE VACCINES - The present invention relates to immunogenic compositions comprising capsular polysaccharide or oligosaccharide of | 2012-08-02 |
| 20120195938 | FORMULATIONS AND METHODS FOR RECOVERY FROM DENTAL SURGERY - Methods and formulations for the improvement of recovery following bone-impacting injury or surgery. The formulations disclosed herein preferably include a blood component with a pharmaceutical agent. The blood component is preferably whole blood or platelet-rich plasma. The pharmaceutical agent may be a glucocorticoid hormone or other organic pharmaceutical agent. Particularly preferred pharmaceutical agents include dexamethasone, betamethasone, triamcinolone hexacetonide, melatonin, purmorphamine, 17β-estradiol, vitamin K | 2012-08-02 |
| 20120195939 | PARENTERAL COMPOSITION COMPRISING MICROSPHERES WITH A DIAMETER BETWEEN 10 AND 20 MICRONS - The present invention relates to pharmaceutical formulations suitable for targeting particular tissue and/or organ(s) with a formulated active ingredient, for example when administered upstream of the target organ or tissue, and to use of the same in treatment methods of preparing the formulations. The pharmaceutical formulations of the invention are for parenteral administration to a target tissue and comprise particles containing an active ingredient, and a biodegradable excipient, wherein 90% or more of the particles have a diameter of between 10 and 20 microns and the formulation is substantially free of particles with a diameter greater than 50 microns and less than 5 microns, such that where the formulation is administered upstream of the target tissue the ability of the active to pass through the target tissue and pass into systemic circulation is restricted. | 2012-08-02 |
| 20120195940 | Nanolipidic Particles - Nanolipidic Particles (NLPs) having average mean diameters of 1 nm to 20 nm are made from a precursor solution. NLPs can be loaded with a desired passenger molecule. Assemblies of these particles, called NLP assemblies, result in a vehicle population of a desired size. Single application or multifunction NLP assemblies are made from the loaded NLPs and range in size from about 30 to about 200 nm. A method of using preloaded NLPs to make larger carrier vehicles or a mixed population provides increased encapsulation efficiency. NLPs have application in the cosmetics, pharmaceutical, and food and beverage industries. | 2012-08-02 |
| 20120195941 | AGENT FOR PROTECTION OF TOOTH SURFACES, IN CONJUNCTION WITH CONVENTIONAL BLEACHING METHODS, BY BIOMIMETIC DEPOSITION OF FLUORAPATITE - An agent for protection of tooth surfaces, in conjunction with conventional bleaching methods, by biomimetic deposition of fluorapatite, containing
| 2012-08-02 |
| 20120195942 | DOSAGE FORMS OF ACTIVE INGREDIENTS CONTAINING HYDROXYSTILBENE FOR TREATING MENOPAUSAL COMPLAINTS - The invention provides novel hydroxystilbene-containing dosage forms, processes for producing these dosage forms and the use thereof for the treatment of menopausal symptoms in women, juvenile oligomenorrhea and dysmenorrhea, primary and secondary amenorrhea or endometritis. | 2012-08-02 |
| 20120195943 | Bone delivery device - Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to subjects. | 2012-08-02 |
| 20120195944 | Rinse-Off Care Products and Consumer Product Line-ups Comprising Same - Consumer product line-ups are provided that include a rinse-off care product that may be used in conjunction with a traditional leave-on antiperspirant or deodorant product to better manage underarm malodor. | 2012-08-02 |
| 20120195945 | Cosmetological and pharmaceutical formulae for the rejuvenation and restoration of skin, including after surgical procedures - This invention is related to pharmacology and cosmetology and may be used in the capacity of a medicinal and cosmetic substance for skin anti-aging, scar reduction, treatment of post-operative peritoneal commissures, increasing the speed of post-operative tissue regeneration, and for the liquidation of cellulite. | 2012-08-02 |
| 20120195946 | Topical Skin Care Compositions and Methods - Topical compositions containing lysate of human parthenogenetic stem cells (hpSCs), preferably within a liposomal dispersion, that reduce the visible signs of skin aging and/or cellulite. | 2012-08-02 |
| 20120195947 | PROTEIN NANOCARRIERS FOR TOPICAL DELIVERY - The invention encompasses nanoparticle assemblies and methods for preparing nanoparticle and compositions comprising such nanoparticles for use in topical or skin applications. The invention further encompasses methods of complexing various molecular and cellular entities to the nanoparticles using the resulting nanoparticles of the invention as delivery devices. The nanoparticles can be used for a variety of applications, such as treating cancer, targeting tumors, reducing the toxicity of a drug in vivo, increasing the efficacy of a complexed agent in vivo, protecting a complexed agent against degradation, increasing skin penetration and retention of drugs, and enhancing the water solubility/dispersibility of a drug or other agent. | 2012-08-02 |
| 20120195948 | Cosmetic Preparation and Method for Preparing the Same - The present invention relates to the use of dedifferentiated plant cells in cosmetic preparations for protecting of stem cells against intrinsic and extrinsic stress factors, in particular for promoting proliferation of stem cells and for protecting them against apoptosis. In particular, the invention relates to the use of dedifferentiated plant cells from fruits of | 2012-08-02 |
| 20120195949 | TURMERIC PIGMENT COMPOSITION AND METHOD FOR PREPARING SAME | 2012-08-02 |
| 20120195950 | Laundry Additive for the Treatment and Prevention of Bed Bugs - A laundry additive such as a fabric dryer sheet formed of a flexible substrate contains an insecticidally effective amount of an insecticide, preferably a pyrethrum, in an amount between about 0.05 and about 10 grams per square foot. Alternatively, the insecticide may be included as a component in a rinse-cycle laundry additive. Such laundry additives are appropriate for use by institutions such as hotels, cruise ships, and nursing homes, hospitals, and shelters in the prevention and control of bed bugs. | 2012-08-02 |
| 20120195951 | Therapeutic Inhibitor of Vascular Smooth Muscle Cells - Methods are provided for inhibiting stenosis following vascular trauma or disease in a mammalian host, comprising administering to the host a therapeutically effective dosage of a therapeutic conjugate containing a vascular smooth muscle binding protein that associates in a specific manner with a cell surface of the vascular smooth muscle cell, coupled to a therapeutic agent dosage form that inhibits a cellular activity of the muscle cell. Methods are also provided for the direct and/or targeted delivery of therapeutic agents to vascular smooth muscle cells that cause a dilation and fixation of the vascular lumen by inhibiting smooth muscle cell contraction, thereby constituting a biological stent. | 2012-08-02 |
| 20120195952 | IMPLANTABLE MATRIX HAVING OPTIMUM LIGAND CONCENTRATIONS - Implantable matrices and methods are provided. The matrices are configured to fit at or near a target tissue site, the matrices comprise biodegradable materials and ligands bound to the matrices and are configured to bind receptors and allow influx of cells into the implantable matrices, wherein the ratio of ligands to receptors is from about 1.5 to about 0.5. | 2012-08-02 |
| 20120195953 | Fibrin sealant (FIBRINGLURAAS) consisting of a kit of lyophilized high concentrate fribinogen intentionally enriched and preserved with fibronolysis inhibitor A1AT - Fibrin sealant (FIBRINGLURAAS®) consisting of a kit of lyophilized high concentrate fribinogen intentionally enriched and preserved with fibronolysis inhibitor A1AT, either non-heated or heating to at least 1° C. and above, preferably at least 101° C., and lyophilized thrombin used to compound glue membrane, the diameter of which is less than 10 micrometers the actual size of the glue membrane of the fibrin sealant (FIBRINGLURAAS®) is from 0.6 μm, to 101° C. heating 0.005 micrometers. Thrombin, a protein, contains good healthy cells. High concentrate fibrinogen, another protein, contains good healthy cells. AFOD (HDL ApoA1), another protein, contains good healthy cells and its topical applications for all solid tumor cancers. | 2012-08-02 |
| 20120195954 | Method of Reducing Appetite - Provided, among other things, is a method of reducing dietary intake comprising: | 2012-08-02 |
| 20120195955 | SUBLINGUAL FILMS - The invention features sublingual film formulations of dopamine agonists and methods of treating Parkinson's disease, tremors, restless leg syndrome, sexual dysfunction, and depressive disorders therewith. | 2012-08-02 |
| 20120195956 | ADHESIVE SKIN PATCH - The present invention provides an adhesive skin patch that permits excellent and prolonged percutaneous absorption of tulobuterol and that can be stably applied to the skin for a long period of time with less skin irritation. The adhesive skin patch comprises a base material and a medicated layer provided on one surface of the base material. The medicated layer contains 1 to 30% by weight of a resolvent, 40 to 98% by weight of a pressure-sensitive adhesive, and tulobuterol. The resolvent contains an aliphatic alcohol having a branched-chain structure or a double bond in its C8 to C30 carbon chain. The pressure-sensitive adhesive is a copolymer obtained by copolymerizing monomers containing 70% by weight or more of an alkyl(meth)acrylate whose alkyl group has 6 to 20 carbon atoms. | 2012-08-02 |
| 20120195957 | NOVEL NANOPARTICLE FORMULATIONS FOR SKIN DELIVERY - Methods and formulations for treating a condition of the skin by delivering therapeutic formulations to the skin that translocates active substances across the stratum corneum barrier to a targeted skin tissue. The methods and formulations comprise active substances encapsulated within surface modified nanostructured lipid carrier nanoparticles. | 2012-08-02 |
| 20120195958 | Implantable devices - The present invention relates to implantable devices, which are coated or coatable with liposomes. The present invention further relates to liposomes encapsulating nucleic acids termed lipoplexes, to methods for the manufacture and coating of such implantable devices, and to the use of such implantable devices to improve treatment of patients with coronary artery disease or other vascular diseases and cancers. | 2012-08-02 |
| 20120195959 | METHOD FOR TREATING DISEASE OR DISORDER OF ADULT CENTRAL NERVOUS SYSTEM ASSOCIATED WITH TISSUE SHRINKAGE OR ATROPHY BY ADMINISTRATION OF INSULIN - The present invention provides a use of an insulin for manufacture of a medicament for treating or preventing a disorder or disease of a central nervous system of an adult individual, wherein the disorder or disease is associated with tissue shrinkage or atrophy. Also provided are methods of treating such disorder or disease using a pharmaceutically effective amount of an insulin or composition that enhances the activity of endogenous insulin. | 2012-08-02 |
| 20120195960 | POST-EXPOSURE THERAPY OF INFLUENZA A INFECTIONS - Poly ICLC or liposome-encapsulated Poly ICLC (LE Poly ICLC) in combination with antisense oligonucleotides (AS) act synergistically in post-exposure prophylaxis or therapy of influenza infections, especially H5N1 virus infections. | 2012-08-02 |
| 20120195961 | Use of Spinosyns and Spinosyn Compositions Against Disease Caused By Protozoans, Viral Infections and Cancer - The present invention relates to the use of spinosyns and spinosyn compositions as pharmaceuticals and methods for treatment—including prevention—of protozoan infections and/or disorders relating to a protozoan infection, such as malaria and | 2012-08-02 |
| 20120195962 | Multiepitope Vaccine for Her2/Neu-Associated Cancers - The present invention includes fusion peptides comprising fragments of the cancer-related protein Her2/neu, methods of preparing such fusion peptides, virosomes comprising such fusion peptides, and uses of such fusion peptides or virosomes for the prevention, treatment or amelioration of a cancer characterized by expression or over-expression of the Her2/neu protein. | 2012-08-02 |
| 20120195963 | HIGHLY PURIFIED ETHYL EPA AND OTHER EPA DERIVATIVES - A pharmaceutical preparation comprising EPA in an appropriately assimilable form where of all the fatty acids present in the preparation at least 90%, and preferably at least 95%, is in the form of EPA and where less than 5%, and preferably less than 3%, is in the form of DHA is provided. | 2012-08-02 |
| 20120195964 | PHOSPHATE-BINDING MAGNESIUM SALTS AND USES THEREOF - The present invention provides, among other things, compositions and methods suitable for the treatment of hyperphosphatemia based on phosphate-binding magnesium salts. In some embodiments, the present invention provides compositions and methods suitable for the treatment of hyperphosphatemia based on the combination of phosphate-binding magnesium and an enteric coating. | 2012-08-02 |
| 20120195965 | SOLID DOSAGE FORM COMPRISING A FIBRATE - The invention provides stable, solid dosage forms and pharmaceutical compositions in particulate form comprising a fibrate, for example fenofibrate, dissolved in an non-aqueous vehicle in order to ensure improved bioavailability of the active ingredient upon oral administration relative to known fibrate formulations. | 2012-08-02 |
| 20120195966 | ORAL DOSAGE FORM FOR MODIFIED RELEASE COMPRISING A JAK3 INHIBITOR - The invention essentially relates to oral dosage forms comprising a JAK3 inhibitor, preferably tasocitinib, suitable for modified release, and processes of preparing such oral dosage forms. | 2012-08-02 |
| 20120195967 | SILK-BASED DRUG DELIVERY SYSTEM - The present invention provides for novel sustained release silk-based delivery systems. The invention further provides methods for producing such formulations. In general, a silk fibroin solution is combined with a therapeutic agent to form a silk fibroin article. The article is then treated in such a way as to alter its conformation. The change in conformation increases its crytallinity or liquid crystallinity, thus controlling the release of a therapeutic agent from the formulation. This can be accomplished as single material carriers or in a layer-by-layer fashion to load different therapeutic agents or different concentrations of these agents in each layer. | 2012-08-02 |
| 20120195968 | CONTROLLED-RELEASE MELATONIN COMPOSITIONS AND RELATED METHODS - This disclosure relates to controlled-release melatonin compositions and related methods. In one embodiment, a controlled-release medicament composition comprises melatonin dispersed in a controlled melatonin release portion comprising a polymer matrix, the polymer matrix adapted to encapsulate the melatonin in a melatonin solubility enhancing pH environment and to maintain the melatonin solubility enhancing pH environment when the composition is located in a melatonin solubility diminishing pH environment for allowing an effective amount of melatonin to be released into the melatonin solubility diminishing pH environment. | 2012-08-02 |
| 20120195969 | TREATMENT OF ACNE BY CONDITIONED MEDIA - Disclosed are methods and compositions for treatment of acne or acneform conditions, particularly but not limited to, acne vulgaris with products generated from culture of stem or progenitor cells. Specifically, compositions of matter are disclosed which are useful for the treatment of acne and acne associated disease states, in particular acne vulgaris, by topical administration of products derived from stem cells or progenitor cells. | 2012-08-02 |
| 20120195970 | Homeopathic Formulations For Treatment Of Herpes Virus Symptoms - Compositions and methods of preparing and using such compositions to treat the symptoms of herpes virus. | 2012-08-02 |
| 20120195971 | Method for Preparing Mechanically Macerated Demineralized Bone Materials and Compositions Comprising the same - The present invention relates generally to methods for preparing mechanically macerated demineralized bone materials that are useful in, or as, implants having a variety of orthopedic applications. More particularly, the demineralized bone materials prepared according to the present invention comprise web-like sections that are compression- and extrusion-resistant and thus, suitable for use in, or as, bone implants or bone grafting materials. Additionally, the web-like morphology increases the surface area of the graft and thereby facilitates the rehydration of the graft, should it be freeze dried. The increased surface area also allows for increased contact with autologous growth factors. The present invention further relates to the demineralized bone materials prepared by the disclosed methods and compositions comprising the same. Methods for preparing a bone void for orthopedic applications, such as bone implants, using the demineralized bone materials or compositions thus prepared are also provided. | 2012-08-02 |
| 20120195972 | OPHTHALMIC FORMULATIONS AND USES THEREOF - Provided by the present invention are compositions or formulations suitable for application to a patient's eyes which utilizes a topical ophthalmically-acceptable formulation comprising a therapeutically-effective amount of an ophthalmically-active antimicrobial agent, and an ophthalmically-active anti-inflammatory or steroidal agent in combination with physiologic levels of serum electrolytes in an ophthalmic formulation for the treatment of changes in the normal eye condition. The invention also includes methods of treating patient's having an ophthalmic disease, injury or disorder, utilizing the compositions or formulations. Also provided are kits comprising the compositions or formulations and a means of applying the compositions or formulation to the patient's eyes. | 2012-08-02 |
| 20120195973 | METHOD FOR ATTENUATING FREE RADICAL FORMATION RESULTING FROM A BODILY INSULT - A method is provided for attenuating free radical formation resulting from a bodily insult. The method includes administering bicarbonate to the body of a subject at a dosage ranging from 1.5 mEq/kg of body weight to 5.0 mEq/kg of body weight within a 24-hour period. | 2012-08-02 |
| 20120195974 | CONTROLLING MEALYBUGS - The invention disclosed in this document concerns controlling mealybugs. | 2012-08-02 |
| 20120195975 | IMMUNE STIMULATORY INFANT NUTRITION - A nutritional or pharmaceutical composition comprising fat, protein, carbohydrate, whey and casein is provided. The composition has a weight ratio of casein to whey between 1:1 to 1:2.4 and comprises: a) at least 3 grams arginine per 100 grams protein; b) at least 10 wt. % linoleic acid based on total fatty acids; c) at least 1 wt. % alpha linolenic acid based on total fatty acids; d) at least one long chain-polyunsaturated fatty acid in an amount exceeding 0.1 wt. % based on total fatty acids selected from docosahexaenoic acid, arachidonic acid and eicosapentaenoic acid; e) 5 to 25 wt. % of at least one polyunsaturated fatty acid based on total fatty acids; and f) 2 to 12 grams indigestible oligosaccharides having a degree of polymerisation of 2 to 100 per 100 gram dry weight of the composition. Methods of treatment by administering the composition are also provided. | 2012-08-02 |
| 20120195976 | METHODS OF TREATING INFLAMMATION BY ADMINISTRATION OF HEME OXYGENASE-1 AND PRODUCTS OF HEME DEGRADATION - The present invention relates to the treatment of disorders using heme oxygenase-1 and heme degradation products. | 2012-08-02 |
| 20120195977 | AURIC ACID ASSISTED SILICON NANOPARTICLE FORMATION METHOD - Embodiments of the invention provide, among other things, a method of preparing nanoparticles including silicon nanoparticles. A mixture is prepared that includes auric acid (HAuCl | 2012-08-02 |
| 20120195978 | CAPCNA PEPTIDE THERAPEUTICS FOR CANCER - Administration of compositions comprising cell-permeable caPCNA-derived peptides and their variants reduces the proliferation of cancer cells and also augments cytotoxic effects of chemotherapeutics. The compositions are effective in cells harboring mutations in DNA repair proteins. | 2012-08-02 |
| 20120195979 | TREATMENT COMPOSITION FOR RECREATIONAL WATER - The present invention is directed to a treatment composition for recreational water, comprising a high molecular weight water soluble resin composition made from long chain alkoxylated polymers or co-polymers that impart emollient properties to the recreational water, as well as articles of manufacture comprising packaging material and the treatment composition for recreational water contained within the packaging material. The present invention is also directed to methods for treating recreational water, and recreational water treated with the above treatment composition. | 2012-08-02 |
| 20120195980 | Method, Composition and Package for Bowel Cleansing - The present invention provides a highly palatable colon cleansing formulation that utilizes a low chloride electrolyte-replenishing base solution. When formulated with polyethylene glycol and a selected sugar alcohol, the formulation offers the advantages of superior palatability without undesirable concomitant side effects or a decrease in cleansing efficacy. | 2012-08-02 |
| 20120195981 | MICRONUTRIENT SUPPLEMENT WITH CALCIUM, VITAMIN D OR CALCIUM & VITAMIN D COMBINATION FOR PREMENSTRUAL SYNDROME, POSTPARTUM DEPRESSION, DEPRESSION AND PANIC ATTACKS - A bolus dose supplement, foodstuff, beverage and beverage concentrate with calcium and vitamin D for the treatment and prevention of PMS, panic attacks, and postpartum depression. The combination of adequate calcium and vitamin D is provided as a multi-vitamin and mineral supplement. The bolus dose is comprised of 2 main ingredients calcium and vitamin D at 1000-1500 mg of elemental calcium in the form of carbonate or citrate or gluconate or citrate maleate and 400-20,000 I.U. of parent vitamin D | 2012-08-02 |
| 20120195982 | Injectible, biocompatible synthetic bone growth composition - An injectible, biocompatible synthetic bone growth composition comprising a mineralized collagen and a calcium sulfate component. The composition is formed into injectible formulation that may be provided at the site of a skeletal defect via minimally invasive manner. An osteoinductive component may be further added, either before or after forming the unitary article. The composition may be formulated as a paste or putty and facilitates bone growth and/or repair. | 2012-08-02 |
| 20120195983 | TREATMENT OF SPECIFIC CARDIOVASCULAR CONDITIONS WITH NITRITE - It has been surprisingly discovered that administration of nitrite to subjects causes a reduction in blood pressure and an increase in blood flow to tissues. The effect is particularly beneficial, for example, to tissues in regions of low oxygen tension. This discovery provides useful treatments to regulate a subject's blood pressure and blood flow, for example, by the administration of nitrite salts. Provided herein are methods of administering a pharmaceutically-acceptable nitrite salt to a subject, for treating, preventing or ameliorating a condition selected from: (a) ischemia-reperfusion injury (e.g., hepatic or cardiac or brain ischemia-reperfusion injury); (b) pulmonary hypertension (e.g., neonatal pulmonary hypertension); or (c) cerebral artery vasospasm. | 2012-08-02 |
| 20120195984 | DIAGNOSIS AND TREATMENT OF THE PRODROMAL SCHIZOPHRENIC STATE - Described herein are compounds (including medical foods, pharmaceutical compositions, methods of compounding them), methods and systems for the diagnosis and/or treatment of prodromal schizophrenia. For example, described herein are methods of treating a developmentally-based neuropsychiatric disorder (schizophrenia) that includes first determining if a subject is at risk for such a disorder by examining phenotypical, serological immune markers and genotypical biomarkers. The biomarkers may be used to tailor the dose to be delivered by the medial food or pharmaceutical composition. Also described are compounds for treating prodromal (rather than full-blown) schizophrenia. | 2012-08-02 |
| 20120195985 | GLYCINE TRANSPORTER-1 INHIBITORS - The present invention provides compounds that are glycine transporter 1 (hereinafter referred to as GlyT-1) inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of GlyT-1 such as cognitive disorders associated with Schizophrenia, ADHD (attention deficit hyperactivity disorder), MCI (mild cognitive impairment), and the like. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds. | 2012-08-02 |
| 20120195986 | PREVENTING OR TREATING PERIODONTAL DISEASES BY HERBAL EXTRACT - A use an extract of Coptidis Rhizoma or a combined extract of Coptidis Rhizoma and Pharbitidis Semen as an active ingredient for preventing and/or treating periodontal disease is provided. The extract of Coptidis Rhizoma or a combined extract of Coptidis Rhizoma and Pharbitidis Semen has activities to stimulate anti-inflammation, osteoblast differentiation and alveolar bone regeneration, and to prevent the alveolar bone destruction, thereby being effective for the prevention and/or treatment of periodontal disease. | 2012-08-02 |
| 20120195987 | SUBSTANCES FOR REDUCING OCCURRENCE OF MAJOR CARDIAC EVENTS COMPRISING EPA OR DERIVATIVES THEREOF, OPTIONALLY, DHA OR DERIVATIVES THEREOF AND MONACOLIN K - Medicaments and therapeutic compositions comprise a composition (1) comprising (A) EPA, pharmaceutically acceptable derivatives of EPA or mixtures thereof, and, optionally, (B) DHA, pharmaceutically acceptable derivatives of DHA or mixtures thereof, wherein the weight ratio of A:B is about 7.5:1 or more, and a composition (2) comprising monacolin K, a source of monacolin K or mixtures thereof. One source of component (1) is fish oil. One source of monacolin K is Red Yeast Rice extract. The compositions are useful for lowering cholesterol and/or triglyceride levels in a subject. | 2012-08-02 |
| 20120195988 | Therapeutic Uses for Plants of the Capsicum Genus - A saponin or a sapogenin, or a saponin or sapogenin derivative, from a plant of the | 2012-08-02 |
| 20120195989 | Carboxymethylarginine Production Inhibitor and Collagen Denaturation Inhibitor - The present invention provides a carboxymethylarginine production inhibitor for inhibiting the production of carboxymethylarginine and a collagen denaturation inhibitor for inhibiting the denaturation of collagen. | 2012-08-02 |
| 20120195990 | Composition to enhanced HDL cholesterol and to decrease intima-media thickening in animals and humans and a method for its preparation - A method of producing a product to correct hypercholesterolemia including pulping fruits of | 2012-08-02 |
| 20120195991 | INJECTION MOLD - An injection mold for molding a product including an insert element, which includes a plurality of terminals each having a contacting portion, includes a male mold and a female mold movably engaged with the male mold. The male mold includes a male platen for fixing a fastening element therein. The fastening element defines a plurality of fastening grooves for fastening the contacting portions in a first male groove opened on the male platen. The male mold further includes a supporting element cooperating with the male platen to fixing a locating mold core in the male platen. A top end of the locating mold core projects into the first male groove and further defines a locating groove for fastening one contacting portion adjacent to a male sprue which is opened on the male platen and connected with the first male groove via a second male groove of the male platen. | 2012-08-02 |
| 20120195992 | METHOD AND APPARATUS FOR TEST PRESSING MULTI-LAYER TABLETS OR COATED TABLETS - The invention relates to an apparatus for test pressing tablets with at least two lavers. | 2012-08-02 |
| 20120195993 | PATTERN TRANSFER METHOD AND IMPRINT DEVICE - In order to allow for aligning a relative position between a transferred object and a stamper with high accuracy without providing an alignment pattern in the transferred object, there are provided: a pattern transfer method, including: when adjusting the relative position between the stamper and the transferred object, a step of detecting at least two or more edge positions of the transferred object and calculating an arbitrary point from the detected edge positions; a step of detecting a position of the stamper from an edge of the stamper or an alignment mark formed in the stamper; and a step of adjusting the relative position between the transferred object and the stamper from the arbitrary point and the position of the stamper; and an imprint device using the same. | 2012-08-02 |
| 20120195994 | METHOD AND APPARATUS FOR MAKING THREE-DIMENSIONAL OBJECTS FROM MULTIPLE SOLIDIFIABLE MATERIALS - Methods and apparatuses for making three-dimensional objects from multiple solidifiable materials is shown and described. Multiple solidifiable material container assemblies are provided for holding different solidifiable materials. Relative movement between the solidifiable material container assemblies and a build platform allows the solidifiable materials to be switched as an object is built. Several exemplary cleaning stations are provided for removing residual solidifiable materials from the surface of the three-dimensional object as it is built to better ensure smooth transitions between materials on the finished object. | 2012-08-02 |
| 20120195995 | ROTATIONAL MOLDING MACHINE AND METHOD - A molding machine apparatus and method for the production of thermoplastic skins or shells by means of what is generally known as rotational or slush molding. The tooling is heated uniformly, rapidly and efficiently by means of high velocity, hot air streams directed at the tooling which create turbulent flow on the surface of the tooling. The air stream is accelerated by means of adjustable nozzles and the air is circulated in the mold by means of a centrifugal fan. | 2012-08-02 |
| 20120195996 | PLASTIC MATERIAL INJECTION MOLDING SYSTEM - A plastic material injection molding system includes a feeding nozzle, a forming mold having a cave therein, and a material-passing mold having a runner therein. The runner communicates both the feeding nozzle and the cave, and has two curved parts therein for slowing down the plastic material injected from the feeding nozzle in order. | 2012-08-02 |
| 20120195997 | Nozzle Assembly Supporting Slide Movement of Valve Assembly - A mold-tool system ( | 2012-08-02 |
| 20120195998 | METHOD AND COMPOSITION FOR ENHANCING MILK PRODUCTION AND MILK COMPONENT CONCENTRATIONS - A method of feeding a ruminant that entails providing a feed that comprises sugar alcohol and at least one additional feed component, where the feed is free of rumen-protected fatty acid or comprises less than 10 weight percent rumen-protected fatty acid, based on the total weight of the feed and further entails orally supplying the feed to the ruminant during a pre-partum period when the ruminant is pregnant, where the ruminant ingests the feed and sugar alcohol during the pre-partum period. | 2012-08-02 |
| 20120195999 | DRINK COMPOSITION - The present invention provides a drink composition for maintaining and/or restoring the fluid balance, for example during a sports event or an exercise containing proteins, carbohydrates and salts. The present invention also provides the use of said drink composition for maintaining and/or restoring the fluid balance during a sports event or an exercise. The present invention also provides a method for treating or preventing dehydration. | 2012-08-02 |
| 20120196000 | PRODUCTION METHOD FOR TRISATURATED FATTY ACID GLYCERIDE CONTAINING OIL COMPOSITION - A trisaturated fatty acid, glyceride-containing oil composition is produced in a step (1) of preparing an oil mixture containing saturated fatty acids (S) in an amount of 45 to 75 wt % and unsaturated fatty acids (U) in an amount of 25 to 55 wt % in all constituent fatty acids by mixing an oil containing SSSs in an amount of 35 wt % or more with an oil having an iodine value of 35 or more; a step (2) of interesterifying the oil mixture with a lipase; a step (3) of obtaining an oil containing liquid and solid oils by crystallizing the oil mixture without use of solvent until the value (X-Y), wherein X is the SSS content (wt %) of the oil after interesterification and Y is the solid oil content (%) during crystallization, becomes 2 to 13; and a step (4) of separating the liquid oil by fractionation of the oil. | 2012-08-02 |
| 20120196001 | COCOA SENSORY CHARACTERISTICS - The present invention relates to cocoa material, such as cocoa beans and products derived therefrom, such as chocolate. The invention in particular relates to flavour characteristics of such cocoa materials. In an aspect, the invention relates to cocoa beans or a derivative thereof of a first origin having at least one sensory characteristic which is substantially equal compared to the corresponding sensory characteristic of a bulk quantity of cocoa beans or a derivative thereof of a second origin, wherein said first and said second origin are different. The present invention also relates to methods suitable for obtaining such coca beans or derivatives therefrom. | 2012-08-02 |
| 20120196002 | METHOD OF PRODUCING A LIPOLYTIC ENZYME - The present invention provides a transformed or transfected | 2012-08-02 |
| 20120196003 | Natamycin-Cyclodextrin Complexes For Use In Foodstuff, Process For Their Manufacture And Use Thereof - The present invention concerns a process for improving the preservation of a bakery product by natamycin. A composition comprising natamycin in the form of a natamycin-cyclodextrin complex is provided and the composition is applied onto a bakery product as an antifungal agent. The invention also concerns a bakery product comprising an effective antifungal amount of natamycin. Another aspect of the invention is an antifungal natamycin composition and the use thereof, which composition has a modified antifungal activity. Further, the invention concerns a process for modifying the antifungal activity of natamycin. | 2012-08-02 |
| 20120196004 | MICROWAVEABLE COATED FOOD PRODUCT, AND METHOD AND APPARATUS FOR THE MANUFACTURE THEREOF - A frozen, microwaveable, coated food product comprising:
| 2012-08-02 |
| 20120196005 | PRODUCTION OF MICROWAVEABLE COATED FOOD PRODUCTS - A method of producing a frozen, microwaveable, coated food product, said method comprising the steps of:
| 2012-08-02 |
| 20120196006 | POWDER COATING PARTICLES IN CRYOGENIC BATH - Embodiments of the present invention relate to a method and apparatus for coating cryogenically frozen particles, such as food particles, with a powder at least in part by random contact with the powder while the particles and powder are circulating in a liquid cryogen. The powder and/or food particles may be electrically charged to increase their affinity for one another as well as the rate of powder coating of the frozen particles. | 2012-08-02 |
| 20120196007 | SOLID CAPSULES COMPRISING ETHANOL, A CARBOHYDRATE, A SALT AND A COATING PROVIDED BY A POWDERING AGENT, PROCESS FOR PREPARING SAID CAPSULES BY SPRAY-DRYING - The present invention relates to a method for the preparation of solid capsules that contain ethanol. The invention further relates to the solid capsules themselves, to products containing them and to a method for improving the storage stability of ethanol containing solid capsules. | 2012-08-02 |
| 20120196008 | Cartridge For The Preparation of Beverages - A cartridge containing one or more ingredients for the preparation of beverages. The cartridge comprises an inlet for the introduction of an aqueous medium into the cartridge, an outlet for a beverage produced from said one or more beverage ingredients, an aperture in a beverage flow path linking the inlet to the outlet which generates, in use, a jet of beverage, and an expansion chamber located downstream of the aperture. The expansion chamber comprises an expansion chamber inlet for receiving the jet of beverage and an expansion chamber outlet; and an air inlet located in the expansion chamber in the vicinity of the expansion chamber inlet. The cross-sectional area of the expansion chamber decreases in a downstream direction from the expansion chamber inlet to the expansion chamber outlet, and the cross-sectional area and profile of the expansion chamber outlet are substantially the same as the cross-sectional area and profile of the beverage stream as it passes through the outlet. | 2012-08-02 |
| 20120196009 | ESPRESSO MACHINE OR FULLY AUTOMATIC COFFEE MACHINE HAVING AUTOMATIC DETERMINATION OF THE GRAIN SIZE DISTRIBUTION AND/OR THE DEGREE OF GRINDING OF GROUND COFFEE - The present invention relates to an espresso machine or a fully automatic coffee machine having a grinder and an infusion device comprising an infuser and an infusion chamber, which is characterised by a volume-determining portion designed to determine the ground volume of a defined quantity of coffee powder ground by means of the grinder, a mass-determining portion designed to determine the ground mass of this quantity of coffee powder, and a calculation portion with which, on the basis of a predefined correlation, which is stored preferably in the calculation portion itself, between the grain size distribution and/or the degree of grinding of ground coffee, on the one hand, and the mass and the volume or a variable derived from these two variables, in particular the density, of ground coffee, on the other hand, there can be calculated from the determined ground volume and from the determined ground mass, the grain size distribution and/or the degree of grinding of this quantity of coffee powder. | 2012-08-02 |
| 20120196010 | Continuous Process for Making a Wheat Tortilla - A continuous process for making a wheat tortilla or other similar products using a continuous pressing step that occurs during a continuous oven initial cooking step or immediately thereafter. Applicants' invention produces a final product with characteristics of a traditionally cooked flour tortilla using equipment that provides for significant increases in manufacturing throughput. The combination of the continuous oven with the concurrent, or relatively concurrent, pressing step substitutes for the hot pressing plates used in previous methods. | 2012-08-02 |
| 20120196011 | METHOD AND APPARATUS FOR SURFACE SANITIZING OF FOOD PRODUCTS IN A COOKING APPLIANCE USING ULTRAVIOLET LIGHT - The present invention provides a method and apparatus for sanitizing consumable products, utensils or any of a variety of products that may benefit from being sanitized using an ultraviolet light source within a cooking appliance, such as a microwave oven. The cooking appliance includes a cooking chamber capable of receiving microwave energy. A UV light source is positioned outside the cooking chamber, and an optical system directs UV light from the UV light source into the cooking chamber. | 2012-08-02 |
| 20120196012 | Adjustable Seasoning Distribution Tube - An apparatus and method for providing a controlled, uniform distribution of seasoning onto snack food products such as potato chips or tortilla chips using an adjustable, segmented seasoning distribution tube adaptable to an existing product line. The tube comprises a base member attached at one end to the delivery device of the seasoning distribution system and at least two segments attached in succession to the base member. Each segment has an opening along the length of the segment, which may be adjusted above or below the longitudinal axis of the tube. | 2012-08-02 |
| 20120196013 | PRODUCTION OF STABILIZED WHOLE GRAIN WHEAT FLOUR AND PRODUCTS THEREOF - A stabilized bran component and stabilized whole grain wheat flour containing the component are produced by subjecting a bran-enriched coarse fraction which contains bran, germ and starch to grinding or milling to reduce grittiness of the coarse fraction without substantially damaging the starch due to abrasion. The coarse fraction may be stabilized by heating to substantially reduce the lipase and lipoxygenase activity of the coarse fraction without substantial starch gelatinization. High levels of natural antioxidants and vitamins are retained while avoiding substantial acrylamide formation during the stabilization. The stabilized coarse fraction or stabilized bran component may be combined with a fine fraction which contains predominantly endosperm to obtain a stabilized whole grain wheat flour. The stabilized whole grain wheat flours and stabilized bran component exhibit extended shelf life and may be used for making baked goods, such as cookies, with desirable oven spread, and a non-gritty mouthfeel. | 2012-08-02 |
| 20120196014 | METHOD AND DEVICE FOR MAKING COFFEE BEVERAGE - A method and a device for making a coffee beverage are provided. The method includes: heating coffee powder by water vapor at a temperature lower than a sublimation temperature of caffeine to sublimate a volatile fat component in the coffee powder without sublimating the caffeine, and dissolving other water-soluble components in water at a temperature lower than 85° C. while only dissolving a little of the caffeine. | 2012-08-02 |
| 20120196015 | Continuous Process for Making a Pita Chip - A continuous process for making a pita chip or other similar products using a continuous pressing step that occurs shortly after a continuous oven initial cooking step. Applicants' invention produces a final product with characteristics of a traditionally cooked pita chip using equipment that provides for significant increases in manufacturing throughput. The use of a continuous oven with the relatively concurrent pressing step allows for the production of a flat chip piece on a continuous product line. | 2012-08-02 |
| 20120196016 | Tank for the storage and/or maturation of an alcoholic beverage - A method and apparatus for the storage and/or maturation of an oxygen sensitive liquid beverage including: a vessel or tank adapted to hold a quantity of the liquid therein, said vessel having a low oxygen transfer rate from the atmosphere facilitating the reductive storage of said liquid; and a means of accommodating a gas permeable membrane, said gas permeable membrane having a high oxygen transfer rate relative to the vessel; wherein said membrane is in contact with said liquid thereby increasing the exposure of said liquid to oxygen in result. | 2012-08-02 |
| 20120196017 | FOOD PREPARATION APPARATUS AND METHOD - A cooking apparatus and method provide for relative movement between a first support member for food items and at least one stop member and/or relative movement between a first support member for food items and a second support member for food items. Relative lateral movement between a first support member and a stop member facilitates rolling movement of rollable food items. Relative up-and-down movement between first and second support members facilitates alternating support and attendant positioning of food items. | 2012-08-02 |
| 20120196018 | Organic Compounds - An orally-administrable product comprising an ingredient or ingredients that have associated with their use an unacceptable aftertaste, and a cooling compound employed as a taste-masking agent in an amount of 0.5 ppm or less. | 2012-08-02 |
| 20120196019 | STEVIA SWEETENER WITH A SURFACTANT - The invention describes compositions that include a stevia sweetener and a surfactant, wherein the concentration of the components provide an improved taste profile where bitterness, after taste and/or lingering of the stevia sweetener is decreased or eliminated. | 2012-08-02 |
| 20120196020 | Feed Block and Method and Apparatus for Manufacturing of the Feed Block - Feed block containing feed particles, at least one binding agent and liquid wherein the binding agent is selected from the group consisting of cold-water soluble starch or cold-water soluble, vegetable protein; and the feed block contains less than 40% of water by weight. Also described is a method for forming a feed block and an apparatus for manufacturing of the feed block. | 2012-08-02 |
| 20120196021 | Fruit and Vegetable Snacks - The present invention discloses formulations for vacuum baked fruit and vegetable snack pieces that have a crispy, crunchy texture similar to potato chip, corn based wafers, and other popular snack items. A fruit or vegetable base is combined with other ingredients and water to make a slurry, which is sheeted and dried in a vacuum belt dryer, and separated into snack sized pieces. In one embodiment, substantial amounts of solid inclusions are combined with the slurry before drying. | 2012-08-02 |
| 20120196022 | Corn Fiber Gum Composites as a Thickener - Disclosed herein is a composition (composite thickener) that generally contains about 1 wt % to about 99 wt % (e.g., 1 wt % to 99 wt %) corn fiber gum (CFG) and about 99 wt % to about 1 wt % (e.g., 99 wt % to 1 wt %) polymer thickener. The polymer thickener may be anionic polysaccharides, cationic polysaccharide, neutral polysaccharides, or mixtures thereof. When applied to aqueous solutions, CFG produced synergistic effects with one or more polymer thickener components and showed a superior thickening effect than individual CFG and other polymer thickener components. | 2012-08-02 |
| 20120196023 | RESISTANT STARCH-RICH STARCH, BEVERAGE AND FOOD USING THE SAME, AND METHOD OF PRODUCING RESISTANT STARCH-RICH STARCH - Disclosed is a resistant starch-rich starch which satisfies the requirements (a), (b), (c) and (d), below:
| 2012-08-02 |
| 20120196024 | REMOVING COMPOUNDS FROM WINE - Methods for improving organoleptic characteristics of wine and/or juice using molecularly imprinted polymers are described. | 2012-08-02 |
| 20120196025 | Infusion preparation device, related method, and resultant product - A device to prepare an infusion, such as a brewed beverage, by moderating and manipulating the extraction rate of a particulate base during an infusion, a related method to prepare such an infusion, and a resultant product of such a method. | 2012-08-02 |
| 20120196026 | STABILIZATION OF CITRUS FRUIT BEVERAGES - A composition which permits protein fortification of citrus juices, particularly orange juice, or beverages containing citrus juices, to be carried out without separation of the juice or beverage and the rapid development of a clear or nearly clear liquid layer on top of the juice or beverage, comprises a soy protein product having a protein content of at least about 60 wt % (N×6.25), preferably at least about 90 wt %, and preferably at least about 100 wt %, which is completely soluble in water at an acid pH value of less than about 4.4 and which is heat stable in aqueous solution, and at least one of at least one calcium salt and at least one organic acid. | 2012-08-02 |
| 20120196027 | MICROWAVEABLE WHOLE OAT FLAKES - A whole oat flake product with hydration rate sufficient to allow quick microwave cooking essentially without boil-up or foam-over. | 2012-08-02 |
| 20120196028 | PREPARATION OF CONTROLLED RELEASE SKELETAL MUSCLE RELAXANT DOSAGE FORMS - The present invention is directed to a method of preparing an extended release pharmaceutical composition comprising cyclobenzaprine, comprising coating inert particles with a cyclobenzaprine-containing a drug layering composition to form IR beads, then coating the IR beads with an extended-release coating to form ER beads. | 2012-08-02 |
| 20120196029 | APPARATUS AND METHOD OF FORMING A UNIFORM GRID LINE - A method for forming a conductive trace on a panel can comprise: determining a height between a sensor and a surface of the panel, adjusting the height if the height does not equal a desired height by creating relative motion between the nozzle and the panel, creating relative motion between the nozzle and the panel in the y direction, and dispensing a conductive ink from the nozzle onto the surface of the panel from a piston dispenser at a rate controlled by a flow regulator to form the conductive trace. The sensor can be in operable communication with a controller and be located a distance of less than or equal to 5 mm from a point where a nozzle dispenses the conductive ink onto the panel. The conductive trace has a uniform width. | 2012-08-02 |
| 20120196030 | Coating Methods and Apparatus - A coating apparatus comprises a coating chamber for coating the articles. The at least one preheat chamber is coupled to the coating chamber. The at least one loading station has a proximal end connectable to at least one of the preheat chambers when in an installed position at a distal end of the preheat chamber. The loading station further includes a carrier for carrying the articles and a drive system. The drive system is positioned to move the carrier between: a loading/unloading position of the carrier in the loading station; a preheat position of the carrier in the preheat chamber to which the loading station is connected; and a deposition position of the carrier in the coating chamber. A gas source is connected to the preheat chamber. | 2012-08-02 |
| 20120196031 | DISPLAY DEVICE AND METHOD OF MANUFACTURING THE SAME - A display device formed by plural pixels that have reflective regions and transmissive regions is disclosed. The display device includes, in each of the pixels: an element layer formed on a substrate; a planarizing layer formed on the substrate to cover the element layer; and a gap adjusting layer formed on the planarizing layer on the element layer. In the display device, the reflective region is formed by an area including the element layer, the planarizing layer, the gap adjusting layer, and a reflection electrode formed on the gap adjusting layer, and the transmissive region is formed by an area including the planarizing layer formed on the substrate excluding an area in which the gap adjusting layer is formed. | 2012-08-02 |
