30th week of 2022 patent applcation highlights part 7 |
Patent application number | Title | Published |
20220233349 | CONTROLLED DRUG DELIVERY OCULAR IMPLANTS AND METHODS OF USING SAME - Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allow for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device. | 2022-07-28 |
20220233350 | OCULAR MEDICATION DELIVERY APPARATUS - An eye medication delivery system and apparatus are disclosed. Preferred embodiments of the inventive system and apparatus provide a gravity vector independent means for safe delivery of a metered mist dosage of ocular medication to a patient's eye and in particular to the cornea. A non-intrusive eye cup is shaped to hold the patient's eye open by a slight pressing action against the orbital socket. This same pressure action activates the metered dosage mist and provides a simple single action for patients to quickly and effectively apply eye medication. In several other embodiments, the apparatus may include a flip up lid to cover and protect the eye cup while not in use and to prevent accidental discharge of the medication. In other embodiments, the apparatus may also incorporate a separate user activation trigger to alternatively control dispensing of the ocular medication. | 2022-07-28 |
20220233351 | CONTACT LENS APPLICATOR - A contact lens applicator for applying a contact lens to an eye of a user includes a base member, a stand, and a lens holder. The base member includes an inner surface and retaining walls. The stand includes a first end, a second end, at least one leg, and a passageway. The lens holder includes a handle, a cup, and a passageway. The first end of the stand removably engages with the handle of the lens holder. The second end of the stand removably engages with the base member. The cup of the lens holder is configured to hold a contact lens. When the lens holder and the stand are removably engaged with the base member, the passageway of the stand and the passageway of the lens holder align above the base member, allowing natural light to pass through the passageways of the stand and the lens holder. | 2022-07-28 |
20220233352 | OPHTHALMIC CANNULA WITH EXTERNAL ENGAGEMENT FEATURE - An ophthalmic surgical system includes a cannula having a receptacle. The receptacle includes a valve and a first lip extending inwardly and defining at least a portion of a chamber in the receptacle. The ophthalmic surgical system also includes a surgical instrument having a second lip that is sized and shaped to engage with the first lip of the cannula to couple the surgical instrument to the cannula. | 2022-07-28 |
20220233353 | OPHTHALMIC CUTTING INSTRUMENTS HAVING INTEGRATED ASPIRATION PUMP - A device for extracting lens material from an eye including a distal, disposable portion releaseably coupleable to a proximal, reusable portion. The disposable portion includes a cutting tube having a distal cutting tip and an inner lumen having a distal end. The disposable portion includes an aspiration pump fluidly coupled to the inner lumen of the cutting tube and a cutting tube drive mechanism configured to oscillate the cutting tube. The reusable portion includes an aspiration pump motor configured to drive the aspiration pump and a coupler for releaseably operatively coupling the pump motor to the aspiration pump. Related devices, systems, and methods are disclosed. | 2022-07-28 |
20220233354 | SYSTEM AND METHOD FOR DELIVERING MULTIPLE OCULAR IMPLANTS - Systems and methods for delivering multiple ocular implants to reduce intraocular pressure are disclosed. The ocular implants can be implanted at multiple sites within a single human eye without requiring removal of the delivery apparatus from the eye. A system for delivering multiple ocular implants can include at least two implants preloaded within a delivery device and configured to be implanted within the eye, a metering device configured to transfer energy to the implants for delivery at selected locations within the eye, wherein the metering device is configured to meter a variable amount of energy for each implant delivery event in the eye. The system can further include an injector mechanism configured to serially engage and drive each of the implants. | 2022-07-28 |
20220233355 | LASER CORNEAL PHOTOABLATION METHOD AND SYSTEM FOR TREATING DRY EYE DISEASE - A laser conical photoablation system in accordance with the present invention comprises a corneal measurement unit configured to measure a cornea and obtain state data of the cornea, a laser control unit configured to control an output intensity and range, an amount, and time of a laser according to a photoablation position and a photoablation shape of the cornea based on a corneal photoablation plan generated based on the state data of the cornea, and a laser module configured to irradiate the cornea with a laser according to a control signal applied by the laser control unit, wherein the state data of the cornea includes a conical surface elevation map, and the laser corneal photoablation system treats dry eye disease by performing corneal photoablation on a surface elevation deviation portion of the cornea. | 2022-07-28 |
20220233356 | FACE SHIELD APPARATUS - A pair of opposed locking clasps couples a temple of a frame to a top bar of the frame. The pair of opposed locking clasps are comprised of a first locking clasp, a second locking clasp, and a hinge. The first locking clasp is comprised of a first base, a nub disposed proximate to a first end of the first base, and a protrusion disposed proximate to a second end of the first base. The second locking clasp is comprised of a second body and an indent that substantially corresponds to a shape of the protrusion, the protrusion being disposed in the indent to lock the first locking clasp to the second locking clasp. The hinge couples the first locking clasp to the second locking clasp. | 2022-07-28 |
20220233357 | Comprehensive Intraocular Vision Advancement - An intraocular implant device for comprehensive intraocular vision advancement includes an intraocular implant body shaped for positioning inside a lens chamber of an eye. In some embodiments, the implant includes an optical adjustable base accommodating lens configured to provide both base adjustment and accommodation. In further embodiments, the implant includes a photoelectric sensor operable to receive incident light through the cornea and to convert the received light into electrical energy for use with one or more circuit components disposed on the body, and wherein the photoelectric sensor is also operable to convert the received light into image data. The ocular implant device may include a projector for projecting the image data onto the retina of a user. The ocular implant may additionally include an autofocusing digital camera, an autofocusing electromechanical lens array, and sensors for detecting glucose levels and/or intraocular eye pressure. | 2022-07-28 |
20220233358 | ELECTROPHYSIOLOGICAL TEST METHOD FOR AUDITORY BRAINSTEM IMPLANT AND RECORDING ELECTRODE USED BY METHOD - The present invention relates to the field of medical devices, and relates to an electrophysiological test method for an auditory brainstem implant (ABI) and a recording electrode used therein. According to the method of the present invention, there is no need to subcutaneously place an additional recording electrode for a patient, which simplifies preoperative preparation. Moreover, the method has advantages of a high signal-to-noise ratio, a fast response speed, a short recording time, and a large anti-interference ability, thus can effectively improve efficiency of intraoperative electrode test. The method is suitable for use in an auditory brainstem implantation surgery. Besides, the present invention enables the auditory brainstem implantation to be located more accurately, thereby expanding a scope of application. | 2022-07-28 |
20220233359 | METHOD AND APPARATUS FOR RELIEVING HEADACHE SYMPTOMS - An apparatus and method for treating symptoms associated with headaches. The apparatus may comprise a bulb, tube, and ear adapter, wherein the tube connects the bulb, in a substantially airtight manner, to the ear adapter. The ear adapter has a passage for gas, e.g., air, to flow from the tube and into an ear. The bulb may be flexible so that the it can be squeezed. Symptoms associated with headaches may be treated by engaging the ear adapter with the ear and performing a series of squeezes and releases with the bulb. | 2022-07-28 |
20220233360 | Moisture And Electromagnetic Radiation Switchable Adhesive And Apparatuses, Systems, And Methods Therefore - This disclosure describes devices, systems, and methods related to dual switchable adhesives, the manufacture thereof, and the use thereof. An exemplary dual switchable adhesive includes one or more polymers, photo initiators configured to cause the one or more polymers to cross-link responsive to receiving light, and polymerization initiators configured to cause the one or more polymers to cross-link responsive to receiving moisture. | 2022-07-28 |
20220233361 | ABSORBENT ARTICLE WITH CONFORMING FEATURES - An absorbent has longitudinal and lateral centerlines, first, second, and target regions, the target region being disposed between the first second regions. Each of the first, second target regions extend laterally across the disposable absorbent article. The disposable absorbent article also has a topsheet; a backsheet; an absorbent core disposed between the topsheet and backsheet; a fluid management layer disposed between the topsheet and absorbent core; and a target zone disposed in the target region. The target zone has a first plurality of conforming features in at least the absorbent core or a combination of the absorbent core and at least one of the topsheet or fluid management layer. The absorbent article also has a long fiber network. | 2022-07-28 |
20220233362 | METHODS AND APPARATUSES FOR ASSEMBLING ELASTIC LAMINATES WITH DIFFERENT BOND DENSITIES FOR ABSORBENT ARTICLES - The methods herein relate to assembling an elastic laminate with a first elastic material and a second elastic material bonded between first and second substrates. During assembly, an elastic laminate may be formed by positioning the first and second substrates in contact with stretched central regions of the first and second elastic materials. The elastic laminates may include two or more bonding regions that may be defined by the various layers or components of the elastic laminate that are laminated or stacked relative to each other. In some configurations, a first plurality of ultrasonic bonds are applied to the elastic laminate to define a first bond density in the first bonding region, and a second plurality of ultrasonic bonds are applied to the elastic laminate to define a second bond density in the second bonding region, wherein the second bond density is not equal to the first bond density. | 2022-07-28 |
20220233363 | WETNESS MONITORING SYSTEM AND METHOD - A method for processing sensor signals representing a wetness event in an absorbent article, the method comprising the steps of: providing an absorbent article comprising a sensor adapted to detect wetness events therein and a first clip-on data processing module in electrical communication with said sensor; providing a database comprising a plurality of information factors, wherein said information factors comprise individualized thresholds for a plurality of absorbent article conditions, each said individualized thresholds being allocated with a corresponding warning condition; receiving from the sensor and/or clip-on data processing module sensor signals representing a plurality of real-time indicators comprising wearing time; wetness events in an absorbent article; interval time between wetness events and/or duration of said wetness event within said absorbent article; processing the sensor signals to determine an absorbent article condition; wherein processing the sensor signals includes combining the information factors with the real-time indicators and, from the sensor signals representative of each individual wetness event: (i) assigning a position of said wetness event within an x, y coordinates of the absorbent article; (ii) grouping wetness event indicators, such as amount of exudate within said wetness event, according to a common position according to step (i); (iii) normalizing the values of the real-time indicators, from the sensor signals; (iv) allocating weightings to the normalised values to generate weighted values for that wetness event; and wherein the weighted values and the grouped wetness event indicators are combined to generate a combined event indicator that is compared with the information factors and when the combined event indicator is equal to one or more of the information factors a signal is generated by the clip-on data processing module according to the one or more corresponding warning conditions. | 2022-07-28 |
20220233364 | ABSORBENT ARTICLE WITH CHANNELS AND METHOD FOR MANUFACTURING THEREOF - A method for manufacturing an absorbent article, said method comprising guiding a first sheet material along a rotating member, wherein a surface of said rotating member is provided with a pattern with at least one suction zone and at least one non-suction zone; applying an absorbent material on said first sheet material on the rotating member; locally removing the absorbent material applied on at least one attachment portion of the first sheet material located above the at least one non-suction zone, such that at least one remaining portion of the first sheet material located above the at least one suction zone is covered with absorbent material and substantially no absorbent material is present on the at least one attachment portion; applying a second sheet material on top of the absorbent material on the first sheet material. | 2022-07-28 |
20220233365 | ABSORBENT ARTICLE WITH REAR POCKET DESIGN - Absorbent articles comprising connecting portions and methods of manufacture are disclosed. In an embodiment an absorbent article may comprise a chassis having a front half section, a rear half section, a body facing surface, and a garment facing surface. The article further comprises an absorbent body and a of containment flaps attached to the body facing surface of the chassis, each of the pair of containment flaps having a flap distal edge. The article may further comprise a connecting portion in the rear half section where the containment flaps and connecting portion define an opening to the body facing surface. The opening may be defined by a pair of laterally opposed edges having a minimum separation distance within the rear end section of between about one-quarter and about three-quarters of a distance between the flap distal edges of the containment flaps. | 2022-07-28 |
20220233366 | ELASTIC LAMINATE WITH HOOKS - Elastic laminate with hooks comprising an upper layer ( | 2022-07-28 |
20220233367 | Patient Transport Apparatus With Adjustable Handles - A patient transport apparatus includes a support structure. The support structure includes a base, a frame, and a patient support surface to support a patient. One or more handle assemblies are coupled to the frame to maneuver the patient transport apparatus. The handle assemblies include one or more handles to be manipulated by a user. The handles are capable of being adjusted to facilitate maneuvering of the patient transport apparatus, such as pushing/pulling the patient transport apparatus along a floor surface, lifting the patient transport apparatus over obstacles, loading the patient transport apparatus into an emergency vehicle, and/or unloading the patient transport apparatus from the emergency vehicle. | 2022-07-28 |
20220233368 | Patient Transport Apparatus With Steer Lock Assembly - A patient transport apparatus comprises a support structure comprising base, a frame, and a patient support surface to support a patient. The apparatus also includes at least one caster assembly coupled to the support structure, with each one of the caster assemblies comprising a wheel, a wheel support coupled to the wheel, and a steer lock assembly movable relative to the wheel support. An actuator is operatively coupled to the steer lock assembly to move the steer lock assembly between a non-steer locked and steer locked state to permit or prevent the wheel support and coupled wheel from swiveling about a swivel axis. The caster assemblies can also include a brake assembly coupled to the wheel, with the actuator operatively coupled to the brake assembly to move the brake assembly between a braked and unbraked state. | 2022-07-28 |
20220233369 | SAFETY ASSISTIVE BELT FOR PATIENT TRANSFER - Described herein is a retractable safety assistive belt assembly for use in transferring disabled or senior patients. The belt assembly includes a retractor assembly, a buckle mechanism, a latch member, a quick-release button, a strap or band member, and an optional belt clip attached to an external part of a housing. The strap or band member optionally includes measurement markers. In a related embodiment, an optional belt assembly case is provided for storage and portability of the belt assembly. | 2022-07-28 |
20220233370 | MOTOR VEHICLE FOR A PERSON WITH REDUCED MOBILITY, WHICH IS EASIER TO GET INTO/OUT OF - The invention relates to a motor vehicle ( | 2022-07-28 |
20220233371 | SMALL ELECTRIC VEHICLE - A small electric vehicle includes: left and right motors connected so as to respectively transmit power to left and right driving wheels; left and right rotation speed sensors; an inclination sensor; a joystick-type operation element; and a control unit, wherein it is configured to calculate target rotation speeds of the left and right motors, based on a target vehicle speed provided by an inclination angle in consideration of the pitch angle and the roll angle detected through the inclination sensor and by an operation position of the operation element, and on a target vehicle angular velocity provided by the inclination angle, by the operation position of the operation element and by the actual speed of the vehicle, and control the left and right motors such that actual rotation speeds of the left and right motors follow the respective target rotation speeds. | 2022-07-28 |
20220233372 | WHEELCHAIR - It is an object to improve riding comfort of a wheelchair having a folding mechanism by keeping an operation part of the folding mechanism from contacting a wheelchair user seated. A folding mechanism includes an operation part for use in changing a state of a left-side support arm and a right-side support arm from one of a folded state or an unfolded state to another. The operation part is arranged below an upper end part of a seat frame with a predetermined space therebetween. | 2022-07-28 |
20220233373 | WHEELCHAIR - An object is to make it easier to lift and move a wheelchair by keeping casters from hanging even when the wheelchair is lifted by one hand. | 2022-07-28 |
20220233374 | WHEELCHAIR - It is an object to make it easy to unfold a wheelchair simply by lifting a part of the wheelchair with one hand. | 2022-07-28 |
20220233375 | CONVERTIBLE MOBILITY DEVICE - The present invention provides an assistive mobility device convertible between a rollator mode and a transport chair mode. | 2022-07-28 |
20220233376 | SMALL ELECTRIC VEHICLE - A small electric vehicle includes: a vehicle body that has a forward and backward direction, and a width direction; left and right driving wheels provided apart in the width direction of the vehicle body; left and right motors connected so as to respectively transmit power to the left and right driving wheels; an operation unit that includes a joystick-type operation piece; and a control unit for controlling the left and right motors according to an amount of operation on the operation piece, wherein the control unit is configured to execute deceleration and stop control when the operation piece is returned to the neutral position during travel, and execute rapid stop control irrespective of an amount of operation in left and right directions when the operation piece is tilted backward during forward travel at a speed equal to or greater than a predetermined threshold. | 2022-07-28 |
20220233377 | SMALL ELECTRIC VEHICLE - A small electric vehicle includes: a body with a forward, backward, and a width direction; left and right driving wheels in the width direction of the body; free wheels, apart from the driving wheels, in the forward and backward direction; left and right motors to respectively transmit power to the left and right driving wheels; left and right rotation speed sensors detecting rotation speeds of the respective motors; an operation unit with an operation element; and a control unit controlling the motors according to an operation on the operation element, the control unit calculates target rotation speeds of the motors, based on a target vehicle speed provided by an operation position of the operation element, and on a target vehicle angular velocity provided by the operation position of the operation element and by the actual speed of the vehicle, and control the left and right motors such that actual rotation speeds of the motors follow the respective target rotation speeds. | 2022-07-28 |
20220233378 | Patient Compliance Monitoring System - A patient compliance monitoring system is provided for monitoring patient compliance in the use of a plurality of patient care and recovery devices in the hospital room. Sensors are associated with each of the devices to detect a usage history of the associated device and to generate usage data therefore. One device is a patient positioning device including a wedge-shaped body with at least one pressure sensor associated with the bottom surface. The wedge-shaped body is formed of a compressible viscoelastic open-cell foam composition that is adapted to compress under the weight so that the angle of the ramp surface of the wedge decreases from an initial ramp angle to a tilt angle for supporting the patient. | 2022-07-28 |
20220233379 | Patient Repositioning Sheet, System, and Method - In one aspect, the present disclosure provides a patient repositioning sheet including an inflatable sheet having a lower layer and an upper layer that are urged apart with inflation of the inflatable sheet. The patient repositioning sheet further includes at least one inflatable support, such as an inflatable wedge. The inflatable wedge has a wedge surface that extends obliquely to the upper layer of the inflatable sheet with the inflatable wedge inflated. | 2022-07-28 |
20220233380 | NEGATIVE-PRESSURE DOME - A negative-pressure dome includes a transparent domed shield, a flexible skirt attached to the perimeter of the domed shield, a hose attachment port formed on the domed shield; and access openings in at least one of the domed shield and the flexible skirt. The transparent domed shield consists of a clear rigid plastic. The access openings may be at least partially occluded by flexible flaps that are deflectable to increase an open cross-section of the access openings. In a first configuration, the access openings are disposed in the domed shield sized to cover a face and are sized to have a cross-section between 3 cm | 2022-07-28 |
20220233381 | SYSTEMS, METHODS, AND DEVICES FOR ARTIFICIAL PLACENTAS AND AMNIOTIC BED INCUBATORS - Described herein are systems, devices, and methods for an extracorporeal, artificial, placenta. In some embodiments, an artificial placenta and amniotic bed system may comprise a control unit, a gas delivery unit, a gas exchange unit or membrane oxygenator, a fluids delivery unit, an amniotic fluid bed, and a human machine interface. In some embodiments, the artificial placenta and amniotic bed systems, devices, and methods described herein may improve survival rates and minimize long-term disabilities in preterm, gestational-age, newborns. In some embodiments, the extracorporeal systems, devices, and methods comprise an artificial network through which oxygen and nutrient-rich blood may flow into a fetus (residing in an amniotic fluid bed), while carbon dioxide and wastes may be removed, thus re-establishing a form of intrauterine placental circulation. | 2022-07-28 |
20220233382 | TIME-BASED WIRELESS PAIRING BETWEEN A MEDICAL DEVICE AND A WALL UNIT - A time-based wireless pairing operation between a medical device, such as a patient bed, and a wall module in a patient room is initiated in response to a power plug of the medical device being plugged into a power receptacle carried by the wall module. Times determined by timers of the medical device and the wall module are compared by the wall module or by the medical device so that wireless pairing occurs only with the medical device that was plugged into the wall module. Different types of plug detectors used in the wall module to detect connection of the power plug include optical detectors, mechanical switches, and current sensors. | 2022-07-28 |
20220233383 | MEDICAL PROCEDURE FACILITATION SYSTEM - A medical procedure facilitation system for use with a bed. The system has a pair of assist arms secured to the bed that may rotate in relation to the bed along a path of rotation. A spring assembly is connected to the assist arms for helping raise a patient's legs. Supportive thigh pads associated with the assist arms give support under the knees and thighs and adjust their angle to accommodate the size and position of the patient. Hand grips are mounted on the support arms that allow the patient to contribute to lifting forces. | 2022-07-28 |
20220233384 | ARM SUPPORT APPARATUS - An apparatus for supporting an arm of a human patient during a medical procedure can include a base, an arm pad, and barriers for shielding scatter radiation. A medial portion of the base can lie between the human patient and a table on which the human patient is supported. The arm pad can be positioned on a lateral portion of the base. A first barrier can be mounted to the base and can be positioned laterally intermediate the medial and lateral portions, the first barrier extending upwardly from the base to above the arm pad. A second barrier can be mounted to the lateral portion of the base and extend downwardly. The arm pad can include a radiopaque panel that is horizontal. | 2022-07-28 |
20220233385 | MODULAR PATIENT POSITIONING SYSTEM - A modular patient positioning system includes: a first pegboard having a first pegboard hole; a second pegboard rotatably coupled to the first pegboard and having a second pegboard hole, the first pegboard and second pegboard lying along a common plane in a first configuration and the first pegboard and second pegboard lying along different planes in a second configuration. A first body portion and a second body portion of a patient's body may be positioned and supported in different planes by having the first pegboard support the first body portion and the second pegboard support the second body portion; and a leg positioner including a mounting structure for mounting the leg positioner on the second pegboard and positioning a leg in a predetermined position relative to the second pegboard. The mounting structure of the leg positioner allows for adjusting axial rotation, abduction/adduction, elevation/depression, and/or flexion/extension of the leg. | 2022-07-28 |
20220233386 | INFLATABLE SUPPORT - An inflatable patient support includes a top panel defining a first perimeter and a bottom panel defining a second perimeter. The second perimeter of the bottom panel is coupled to the first perimeter of the top panel. An internal wall is coupled between the top panel and the bottom panel to define a first chamber and a second chamber. The internal wall defines at least one passage therethrough that allows fluid communication between the first chamber and the second chamber. The first chamber and the second chamber are inflatable. | 2022-07-28 |
20220233387 | ANKLE EXOSKELETON SYSTEM AND METHOD FOR ASSISTED MOBILITY AND REHABILITATION - A powered exoskeleton is designed to provide assistance to a user, where the powered exoskeleton may have power-generating elements in one location and power-applying elements in another location, so that a user can easily wear the powered exoskeleton. | 2022-07-28 |
20220233388 | ASSISTED EXOSKELETON REHABILITATION DEVICE - The present disclosure relates to an assisted exoskeleton rehabilitation device, comprising: a back structure comprising a back crossbeam, a back supporting panel with an adjustable length, and a shoulder pneumatic muscle element mounted on the back supporting panel; an arm structure; a shoulder joint assembly, by which the arm structure is connected to an upper end of the back structure; and a waist structure. An upper end of the back supporting panel is fixedly connected to the back crossbeam, and a lower end thereof is fixedly connected to the waist structure. The shoulder joint assembly comprises a curved shoulder joint connecting panel, a shoulder traction wheel, a shoulder traction line, a first hinge mechanism and a second hinge mechanism. One end of the shoulder joint connecting panel is connected to the upper end of the arm structure by the first hinge mechanism to form a bend-stretch revolute pair of the shoulder joint, and the other end of the shoulder joint connecting panel is connected to the back crossbeam by the second hinge mechanism to form an abduction-adduction revolute pair and a medial rotation-lateral rotation revolute pair of the shoulder joint assembly, and the shoulder traction wheel is fixed to the upper end of the arm structure. The shoulder traction line is connected at one end to the shoulder traction wheel, and connected to the shoulder pneumatic muscle element at the other end. | 2022-07-28 |
20220233389 | PORTABLE ROBOTISED APPARATUS WITH FUNCTIONAL ELECTROSTIMULATION FOR ASSISTED JOINT REHABILITATION - A portable robotised apparatus with functional electrostimulation is provided having an auxiliary actuator for the limb joint to be rehabilitated; an orthosis for attaching to the patient; sensors for measuring parameters; and an autonomous power source. The portable robotized apparatus is characterised in that it also has: a 16-channel electric-pulse generator; a non-invasive multielectrode array; control electronics, to coordinate the actuator and the electric pulse generator, collect the measurement from the sensors and carry out real-time control; and a control algorithm to command, inter alia, the electric-pulse generator. The actuator operates in a coordinated manner in real time with the electric-pulse generator which is applied to the affected limb by means of the electrode array. | 2022-07-28 |
20220233390 | MOVEMENT-DEPENDENT STABILIZATION SUPPORT SYSTEM - The present invention relates to a movement-dependent stabilisation support system ( | 2022-07-28 |
20220233391 | HUMAN-INTERFACE DEVICE AND A GUIDING APPARATUS FOR A VISUALLY IMPAIRED USER INCLUDING SUCH HUMAN-INTERFACE DEVICE - A human-interface device and a guiding apparatus for a visually impaired user including such human-interface device. The human-interface device includes a tactile module arranged to provide a set of haptic signals to a user, wherein the tactile module has a plurality of tactile units each arranged to provide at least a first haptic signal and operable to cooperate with one or more of other tactile units to provide different haptic signals. | 2022-07-28 |
20220233392 | INFORMATION PROCESSING DEVICE AND INFORMATION PROCESSING METHOD - An information processing device calculates an occupancy rate of a pedestrian crossing in an image obtained by capturing an image of a traveling direction of a target person, determines a crossing status of the target person for the pedestrian crossing based on the calculated occupancy rate, and generates support information for supporting the target person crossing the pedestrian crossing based on the crossing status. | 2022-07-28 |
20220233393 | MASSAGER - Provided is a massager having a body, a massage attachment and at least two triggers for operation. The massage attachment may be removeably coupled to the massager and easily changed. The first trigger may allow a user to operate the massager in a first orientation and the second trigger may allow a user to operate the massager in a second orientation. A gripping surface may allow the user to effectively grip the massager in either the first or the second orientation while also allowing the user to operate one of the first or second triggers. | 2022-07-28 |
20220233394 | Sex Toy as Vibrator for Erogenous Stimulation, Method, and Use - Sex toy as a vibrator for erogenous stimulation, including an electric motor drive that rotationally drives at least one eccentric inertial mass. The inertial mass eccentrically rotates in a rotational frequency range, and therefore the vibrator vibrates in this frequency range and thus in its working oscillation frequency range. The diameter of the motor drive is between 5 mm and 50 mm. The vibrator is designed in such a way that during operation it is virtually acoustically imperceptible. | 2022-07-28 |
20220233395 | Compression Wave Massage Device - A compression wave massage device for body parts is described, particularly for erogenous zones such as the clitoris, comprising a pressure field generation device and a drive device. The pressure field generation device has at least one cavity with a first end and a second end, located opposite the first end and distanced from said first end, with the first end being provided with at least one opening for placement on a body part. The drive device causes a change of the volume of at least one cavity between a minimal volume and a maximal volume such that in at least one opening a stimulating pressure field is generated. The cavity is formed by a single chamber, and the ratio of the volume change to the minimal volume is not below 1/10, preferably not below ⅛. | 2022-07-28 |
20220233397 | FASCIAL GUN HAVING FUNCTION OF INTELLIGENTLY ADJUSTING STRIKING - This present invention discloses a fascial gun having a function of intelligently adjusting striking, including a fascial gun body and an electric power device. The fascial gun body includes a fascial gun housing and a massage head, and the fascial gun housing is provided therein with a main circuit board with an MCU, a motor electrically connected to the main circuit board, and a reciprocating mechanism connected to an output shaft of the motor. The electric power device supplies electric power to the main circuit board, the reciprocating mechanism is provided with a sliding shaft which penetrates through the fascial gun housing and is connected to the massage head, the main circuit board is electrically connected to a detection device used for detecting the operating state of the fascial gun, and the MCU controls the rotation speed of the motor according to information sent by the detection device. | 2022-07-28 |
20220233398 | MASSAGE DEVICE - A massage device includes a base, a driving module, a massage head, an enclosure, and a heating module. The massage head is connected to the driving module, a side of the massage head away from the base is provided with a massage protrusion, and a first cavity is formed on a side of the massage head facing the base. The enclosure is arranged between the base and the massage head, an end of the enclosure away from the base is arranged close to an end of the massage head close to the base, a second cavity in communication with the first cavity is formed in the enclosure, and the second cavity and the first cavity jointly form a heating chamber. The heating module is accommodated in the heating chamber and fixed relative to the base. | 2022-07-28 |
20220233399 | VIBRATING THERAPY SYSTEM AND DEVICE - A vibration therapy device that includes a housing that includes a handle portion, a head portion and a module seat defined on the head portion, an electrical source, a motor positioned in the housing, a switch for activating the motor, a push rod assembly operatively connected to the motor and configured to reciprocate in response to activation of the motor, and a therapy module removably secured to the module seat. The distal end of the push rod assembly is configured to removably receive a reciprocating attachment thereon. The therapy module at least partially surrounds the distal end of the push rod assembly. | 2022-07-28 |
20220233400 | MASK, AND SKIN CARE APPARATUS COMPRISING SAME - A mask according to an embodiment comprises: a first substrate disposed on a first base layer; a first wire disposed on the first substrate; a piezoelectric element disposed on the first wire; a second wire disposed on the piezoelectric element; a second substrate disposed on the second wire; a second base layer disposed on the second substrate; and a cavity disposed between the first base layer and the piezoelectric element, wherein the cavity is disposed in a region overlapping the piezoelectric element in a vertical direction. | 2022-07-28 |
20220233401 | SPA STRUCTURAL PADDLE ASSEMBLY SYSTEM - A system for supporting a spa shell may include a structural support paddle. The paddle may include a base portion and a paddle portion, connected to each other through an articulating joint such as a ball-and-socket. The top side of the paddle portion may include one or more pieces of cushioning material, such as EPF foam. The structural paddle assembly may be placed between the base of the spa and the spa shell. Typically 5 or more paddle assemblies are place in a spa for support, such as in the lowest areas of the spa shell and/or concavities, or convexities, of the spa shell. Compared to typical large blocks of foam used to support a spa shell from beneath, the structural support paddles provided increased room below the spa shell for ease of maintenance and installation, and more directly controlled support. | 2022-07-28 |
20220233402 | BIOPROCESS VESSELS WITH INTEGRATED PUMP - A bioprocess vessel includes a flexible bag or substantially rigid container that defines an interior volume and having a bottom surface, the bottom surface being open or containing an aperture therein for the passage of fluid. A pump is secured to the bottom surface of the flexible bag or substantially rigid container. In some embodiments is secured directly to the flexible bag or substantially rigid container. In other embodiments, the pump is secured indirectly the flexible bag or substantially rigid container using, for example, a port that extends through the aperture on the bottom surface. The port or flanged surface may also be integrated into the pump, which is secured to the vessel. An optional mixing adaptor may be provided inside the interior volume of the flexible bag or substantially rigid container and at least partially covers the inlet that leads to the pump. | 2022-07-28 |
20220233403 | INFUSION BAG OF MIDAZOLAM FOR INTRAVENOUS USE - The invention relates to an infusion container comprising a sterile, ready-to-use, stable aqueous solution of Midazolam or a pharmaceutically acceptable salt thereof, suitable for direct intravenous infusion to a patient in need thereof. The invention also relates to a novel infusion container having plurality of ports that is suitable for delivering or receiving a sterile fluid, such as the said stable aqueous solution of Midazolam or a pharmaceutically acceptable salt thereof. | 2022-07-28 |
20220233404 | CONTAINERS, COMPOSITIONS, AND METHODS RELATED TO CANNABINOID ANIONS - Various aspects of this patent document relate cannabinoid anions including methods to produce cannabinoid anions, compositions comprising cannabinoid anions, containers that contain compositions comprising cannabinoid anions, and methods to consume cannabinoid anions. | 2022-07-28 |
20220233405 | AUTOMATIC DRUG COMPOUNDER WITH HYGROSCOPIC MEMBER - Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes fluid pathways controllable by valves of the cartridge. A pump component within the cartridge is actuable to move fluid through the controllable fluid pathways. The cartridge includes a needle extending from a cartridge body and fluidly coupled to at least one of the controllable fluid pathways. A vial puck is provided for attachment to a vial to be fluidly coupled to the cartridge by the needle. The vial puck may include a hygroscopic member to absorb fluid from the needle to ensure a dry disconnect. A shuttle valve may also be provided. | 2022-07-28 |
20220233406 | ITEM STORAGE APPARATUS AND MEDICINE-TAKING SUPPORT APPARATUS - An item storage apparatus includes a first storage to store items, a carrier to take an item from the first storage and convey the item, a first support supporting the carrier to be movable back and forth in a first horizontal direction, a second support supporting the first support to be movable back and forth in a second horizontal direction perpendicular to the first horizontal direction, a vertical moving mechanism supporting the second support to be movable back and forth in a vertical direction perpendicular to the first horizontal direction and the second horizontal direction, and a second storage to store the item. At least one of the first or second storage has a multi-tier structure in which a space for movement of the carrier is between tiers. The first support has a cantilever structure in which one end is secured to the second support and another end is free. | 2022-07-28 |
20220233407 | Method and Apparatus for Assisting, Checking, and Confirming Nasogastric and Orogastric Tube Insertion and Placement - A long, thin, flexible medical apparatus, a kit, and a method placing, confirming, and visualizing placement of a gastric tube. The apparatus comprises an elongate body portion, a handle, and a distal tip portion. An ability to insert and remove the body and distal tip portions in relation to the gastric tube over the length of the long, thin, flexible structure provides a positive indication that the lumen is not blocked, obstructed, or otherwise compromised over that length. pH indicator sensors and, additionally or alternatively, radiopaque markers may be retained by the distal tip portion. The pH sensors exhibit a verifiable color change in response to contact with a predetermined subject fluid. The radiopaque markers enable a determination with certainty of the location and orientation of the distal tip portion of the apparatus and of the distal portion of a gastric tube in which the apparatus is disposed. | 2022-07-28 |
20220233408 | Retractable Pacifier System - A method and apparatus can include: a shield; a shaft coupled to the shield; a nipple coupled to the shaft; and a membrane coupled between the shield and the shaft, the membrane providing a retracted configuration creating a storage cavity for the nipple based on the shaft being pulled away from the shield, and the membrane providing an extended configuration with the nipple exposed and extended past the shield based on the shaft being pressed toward the shield and the membrane inverting from the retracted configuration. | 2022-07-28 |
20220233409 | GLASS IONOMER CEMENT COMPOSTION FOR DENTAL PURPOSES AND METHOD FOR PREPARING THE SAME - The present specification provides a dental glass ionomer cement (GIC) composition comprising a zwitterionic material and a glass ionomer cement, and a method of preparing the same. | 2022-07-28 |
20220233410 | COMPOSITION FOR FORMING COATING FILM AND ULTRAFINE SHORT FIBER - Provided is a composition containing fine fibers for forming a coating film. The composition has excellent spreadability and provides a coating film with excellent uniformity by application to a skin. | 2022-07-28 |
20220233411 | RECONSTITUTABLE SANITISER - A reconstitutable sanitiser formulation which is non-alcoholic in nature and achieves up to 99.9% reduction in microbial load and provides long-lasting protection against microbes for 2-6 hrs. | 2022-07-28 |
20220233412 | MICROPARTICLES COMPRISING CELLULOSE NANOCRYSTALS AGGREGATED WITH PROTEINS AND COSMETIC USES THEREOF - Proteinaceous cellulose microparticles are provided. These microparticles comprise cellulose nanocrystals and one or more peptide, one or more protein, or a mixture thereof, wherein the nanocrystals and the peptide(s) and/or protein(s) are aggregated together to form the microparticles. In embodiments, the microparticles comprise silk fibroin and advantageously are hydrophobic and lipophilic. There are also provided cosmetic preparations comprising these microparticles. In advantageous embodiments, these cosmetic preparations comprise a water-in-oil emulsion or a lipophilic medium. Finally, there are also provided methods of producing the microparticles. | 2022-07-28 |
20220233413 | MONODISPERSE EMULSIONS TEMPLATED BY THREE-DIMENSIONAL STRUCTURED MICROPARTICLES AND METHODS OF MAKING THE SAME - An emulsion system includes a plurality of monodisperse particle-drops. Each particle-drop is formed by a single elongated drop-carrier particle disposed in an oil-based continuous phase, wherein the single elongated drop-carrier particle comprises an elongate body with an opening at one end thereof. The single elongated drop-carrier particle has a hydrophilic interior region containing an aqueous droplet and a hydrophobic exterior region. The aqueous droplet and/or a surface of the hydrophilic interior region may contain one or more reagents, analytes, labels, reporter molecules, and/or cells. | 2022-07-28 |
20220233414 | MASCARA COMPOSITION AND METHOD OF USE - A method for improving the curl of eyelashes is provided. A composition is applied to eyelashes, and a magnetic element is then moved above the eyelash in the direction of desired curl. The disclosed composition, which may also be provided separately or in a kit along with a magnetic element for use with the disclosed method, requires three components: (i) one or more iron oxides in a total amount of at least 20% by weight, (ii) one or more latex polymers present in a total amount of at least 6% by weight; and (iii) one or more waxes having a melting point T | 2022-07-28 |
20220233415 | Solid Oral Care Compositions - This invention relates to solid oral care compositions, for example a tablet, comprising a binder system. In certain aspects the invention is directed to solid oral care compositions that are tablets that comprise a binder system, wherein the binder system comprises polyvinyl pyrrolidone and hydroxyethyl cellulose, and to methods of using and of making these compositions. | 2022-07-28 |
20220233416 | Process For Making An Oral Care Article Of Manufacture - A process, for example a continuous process, for making an oral care article of manufacture containing a fibrous composition, for example a composite structure, and more particularly to a process for making an oral care article of manufacture containing a fibrous composition, such as a soluble fibrous composition, containing soluble filaments is provided. | 2022-07-28 |
20220233417 | PEROXIDE GEL COMPOSITIONS - The present invention is a formable dental treatment tray utilizing poly(2-ethyl-2-oxazoline) and a gelatinous active. Blending of the active is accomplished by mixing the Poly(2-ethyl-2-oxazoline) with an active ingredient, such as a peroxide like hydrogen peroxide, carbamide peroxide, sodium perborate, or sodium percarbonate, usually also with water or an appropriate organic solvent. Peroxide concentrations in these new gels can reach a 30% concentration of hydrogen peroxide while maintaining a shelf life of six months at room temperature without developing peroxide decomposition. The gels are applied to an appropriate backing and dried to a gelatinous state. In use, the active is hydrated and regains adhesiveness. Then the tray is pressed and formed around a user's dental arch to form the customizable tray. Multiple active ingredients may be used, with or without peroxide, for accomplishing desired treatment regimens. | 2022-07-28 |
20220233418 | SKINCARE FORMULATIONS WITH POLYGONAL PRISMATIC PLATELET UV FILTERS - A skincare formulation including a prismatic UV filter and polygonal Zinc oxide prismatic platelets composed of primary nanoparticles as an active substance, wherein the skincare formulation is preservative-free or includes one or more preservatives in a total concentration of 2% (w/w) or less with respect to a total weight of the skincare formulation. | 2022-07-28 |
20220233419 | METHOD FOR PREVENTING ADHESION OF ATMOSPHERIC TOXIC SUBSTANCE - Disclosed is a method for suppressing adhesion of air harmful substances, including applying an external preparation to skin to suppress adhesion of air pollutants to the skin, wherein the external preparation contains the following component (A) and component (B), and the ratio by mass of the content of the component (A) to the content of the component (B) in the external preparation [(A)/(B)] is 0.30 or more and 5.0 or less. Component (A): a metal oxide having an average primary particle diameter d | 2022-07-28 |
20220233420 | Personal Care Composition - An antiperspirant and/or deodorant composition including from 0.01 weight % to 0.15 weight % flaxseed oil and from 0.5 weight % to 5.0 weight % taurine. | 2022-07-28 |
20220233421 | ULTRAVIOLET ABSORBER, PREPARATION METHOD THEREFOR, AND ULTRAVIOLET SCREENING PRODUCT CONTAINING SAME - The present disclosure relates to an ultraviolet absorber, a preparation method therefor, and an ultraviolet screening product containing same and, more specifically, to: an ultraviolet absorber, which comprises polymeric carbon nitrides having a heterocyclic structure comprising C and N; a preparation method therefor; and an ultraviolet screening product containing same. | 2022-07-28 |
20220233422 | ANTIMICROBIAL ANTIFUNGAL COMPOSITION - A synergistic antimicrobial composition for use in personal care products functions as an antifungal agent in hair shampoo and hair care products, and includes (A) an undecylenic acid based phosphobetaine depicted by Formula I, where R=Undecylenic acid: | 2022-07-28 |
20220233423 | INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL - It is an object of the present disclosure to provide a method for the preparation and use of an agent for coloring keratinous material, in particular human hair, comprising the following steps:
| 2022-07-28 |
20220233424 | Skin Care Composition and Method of Using the Same - A skin care composition that includes a combination of palmitoyl dipeptide-7, acetyl tetrapeptide-11, other optional skin ingredients, and a dermatologic ally acceptable carrier. The combination of peptides synergistically improves cellular ATP level and/or upregulates the expression of peroxisome proliferator activated receptor alpha and/or methylsterol monooxygenase 1 to help provide improved skin health and appearance. | 2022-07-28 |
20220233425 | ANTI-INFLAMMATORY PEPTIDES, AND USES THEREOF - An anti-inflammatory peptide comprises an anti-inflammatory fragment of a protein selected from SEQUENCE ID NO's: 1 to 16, the anti-inflammatory fragment being 7 to 37 amino acids in length and having a charge of between −9 and +3; wherein the c-terminal amino acid is not cysteine (C) or methionine (M), and the n-terminal amino acid is not cysteine (C), histidine (H), proline (P) or threonine (T). The anti-inflammatory fragment does not contain cysteine (C). The anti-inflammatory fragment is from a region of the proteins of SEQUENCE ID NO's: 1 to 16, which region is characterised by being 17 to 109 amino acids in length and having a charge of between −6 and +4, wherein the c-terminal amino acid of the region is not aspartic acid (D), phenylalanine (F), methionine (M) or tryptophan (W), and the n-terminal amino acid of the region is not aspartic acid (D), histidine (H), methionine (M), proline (P) or tryptophan (W). Examples of peptides are provided in SEQUENCE ID NO's: 71 to 221. | 2022-07-28 |
20220233426 | Gel Texturizer Base for Cosmetics - This invention provides for a gel texturizer base for cosmetic products. The bases are excipients that provide a gel-like texture to cosmetic products. The gel texturizer bases of this invention are from non-petroleum based products and comprise over 85% juice derived solvent with the balance being a combination of a texture enhancer and a gum texture modifier. | 2022-07-28 |
20220233427 | CLEANSING COMPOSITION - An aqueous, sulphate free shampoo composition for hair and scalp comprising:—a. a pre-formed emulsified silicone; b. a cationic deposition polymer; c. a hair substantive cationic conditioning polymer which is an APTAC polymer having a molecular weight of less than 1 million Daltons, preferably selected from a homopolymer of (3-acrylamidopropyl) trimethyl ammonium chloride and a (3-acrylamidopropyl) trimethyl ammonium chloride/acrylamide copolymer; d. a total amount of anionic surfactant, amphoteric surfactant and zwitterionic surfactant consisting of: (i) from 3 wt % to 13 wt %, by weight of the total composition at 100% activity, of an alpha olefin sulfonate anionic surfactant of general formula (I): R | 2022-07-28 |
20220233428 | HAIR TREATMENT METHOD - A method for treating hair, comprising steps 1 and 2 below:
| 2022-07-28 |
20220233429 | PERSONAL CARE AEROSOL COMPOSITIONS, METHODS AND DEVICES - Disclosed are personal care formulations for delivery to the skin of a person in the form of an aerosol comprising: (1) non-propellant components comprising at least one active ingredient in the form of finely divided particles, at least one hydrophobized clay, a hydrophobic carrier comprising trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) and at least one co-carrier wherein: (i) the weight ratio of said trans-1233zd:co-carrier is from about 0.25:1 to about 4:1; (ii) said trans-1233zd and said co-carrier together comprise at least about 40% by weight of said hydrophobic carrier. | 2022-07-28 |
20220233430 | LACTOBACILLUS PLANTARUM FOR SKIN CARE - The present invention relates to microorganisms for use in the treatment and/or prevention of skin conditions by topical application. In particular, the microorganisms are for use in the treatment and/or prevention of loss of skin barrier function, inflammatory conditions and/or growth of pathogenic microorganism. The invention further relates to pharmaceutical or cosmetic compositions or products comprising the microorganisms Provided is also a cosmetic use of the microorganisms or compositions for application on the skin and a cosmetic method, in particular to improve the appearance of the skin. | 2022-07-28 |
20220233431 | COSMETIC COMPOSITION COMPRISING A COMBINATION OF AT LEAST ONE OLIGOSACCHARIDE AND/OR POLYSACCHARIDE COMBINED WITH A MANNOSE MONOSACCHARIDE, AND USE THEREOF IN MAINTAINING THE BALANCE OF THE BACTERIAL SKIN FLORA - The present invention relates to a cosmetic composition for topical application, comprising, in a physiologically acceptable medium:
| 2022-07-28 |
20220233432 | SELF-FUELED PARTICLES FOR PROPULSION THROUGH FLOWING AQUEOUS FLUIDS - A simple, self-propelling particle system is disclosed that can deliver a cargo through flowing aqueous solutions. This disclosure provides a non-aqueous composition comprising: (i) particles formed of a carbonate salt and having an average diameter of about 100 μm or less; and (ii) an acid in solid form. The particles may be associated with a cargo molecule or particle. In mouse models of severe hemorrhage, the propelled particles are able to deliver a procoagulant enzyme and halt bleeding. | 2022-07-28 |
20220233433 | Device in the Form of a Cannabinoid-Based Polymer Matrix - The invention relates to a device for topical application in the form of a polymer matrix containing at least one active ingredient from the family of cannabinoids, alone or as a mixture with other active ingredients. The invention preferably relates to the device in the form of a collar, to the use thereof for improving the well-being and the mobility of an animal to which the device is applied, and to a process for producing the device. | 2022-07-28 |
20220233434 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PRESBYOPIA - The invention provides compositions and methods for the treatment of presbyopia. The compositions comprise aceclidine hydrochloride, polysorbate 80, mannitol, anhydrous hypromellose, disodium edetate dihydrate and anhydrous sodium citrate and optionally brimonidine, benzalkonium chloride and/or sorbic acid. | 2022-07-28 |
20220233435 | CONTROLLED RELEASE DEVICE FOR ORAL CAVITY - The present invention relates to a controlled release device for oral cavity, which is attached on a hard dental surface of a tooth. The attachment is done using any adhesive layer that can attach on enamel surface of a tooth or using a holder attached to the hard dental surface, to which holder the device can be attached, clipped or fastened. The device comprises of two or more polymeric materials forming a polymer matrix or matrices. The polymer matrices incorporate one or more agent(s), which release rate in the oral cavity can be con-trolled with the polymeric materials in the matrices. The invention also relates to a method producing a controlled re-lease device for delivering an agent to the oral cavity. | 2022-07-28 |
20220233436 | METHOD OF USING NEBULIZED ALCOHOL FOR ANALGESIA - A method of regulating pain in a patient includes operations of measuring a patient pain level, determining a dose of ethanol which does not trigger alcohol intolerance or intoxication, delivering the dose of ethanol to the patient by inhalation from an active mesh nebulizer at a repeated interval, measuring the pain level of the patient at a monitoring interval, and determining, based on the patient pain level, whether to adjust the ethanol dose. The dose of ethanol is delivered in the form of particles of nebulized liquid having a diameter ranging from about 0.5 μm to about 5.0 μm, which are rapidly absorbed into the bloodstream of a patient and delivered to the brain. | 2022-07-28 |
20220233437 | DEVICES, COMPOSITIONS AND METHODS FOR COLONIC MICROBIOME ENGRAFTMENT - Provided herein are compositions, including products of manufacture such as formulations, and kits, and methods, for treatment, amelioration or prevention of a disease, infection or condition caused or exacerbated by a pathological or abnormal in situ microbiome space, or a gastrointestinal (GI), disease, infection or condition or a disease or condition caused by, initiated by or exacerbated by a pathological microbiome, e.g., by a pathological GI or colonic microbiome residing in a gut mucosa. | 2022-07-28 |
20220233438 | MICELLE FOR SOLUBILIZING A SPARINGLY WATER-SOLUBLE INGREDIENT AND SOLUTION COMPRISING THE SAME - The present invention provides a micelle comprising an anionic micelle and a protecting agent surrounding the anionic micelle, the anionic micelle being formed from, as a structural unit, an ingredient that has a functional group capable of being anionized under basic conditions and has anionic micelle-forming ability, the protecting agent protecting the anionic micelle. The present invention also provides a micelle comprising a cationic micelle and a protecting agent surrounding the cationic micelle, the cationic micelle being formed from, as a structural unit, an ingredient that has a functional group capable of being cationized under acidic conditions and has cationic micelle-forming ability, the protecting agent protecting the cationic micelle. | 2022-07-28 |
20220233439 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING SKIN DISEASES - Topical pharmaceutical compositions include tazarotene or a pharmaceutically acceptable salt of tazarotenic acid and an oil-in-water emulsion vehicle that forms a lotion. The compositions are used to treat skin diseases, such as acne vulgaris. | 2022-07-28 |
20220233440 | NANO- OR MICRO-EMULSION COMPOSITIONS AND METHODS OF USE THEREOF - The present disclosure provides all-natural nano- or micro-emulsions for the treatment of the skin, hair follicles, and related conditions, methods of using such nano- or micro-emulsions, and methods for preparing such nano- or micro-emulsions. The present disclosure relates to nano- or micro-emulsion formulations with improved bioavailability, time of onset, cellular permeability, and viscosity that can be suitable for topical, sublingual, oral, and/or nasal administrations. The current disclosure also includes compositions and methods for improving the bioavailability and the onset of actions arising from the particular components within the nano- or micro-emulsion formulations of the present disclosure. | 2022-07-28 |
20220233441 | MICROEMULSION DELIVERY SYSTEMS FOR CANNABIS EXTRACTS AND TERPENES - Microemulsions are described where hydrophobic liquid droplets are distributed in a continuous hydrophilic liquid phase. The described microemulsions may be thought of as modified oil-in-water (MOIW) microemulsions, where both the “oil” and “water” phases of the microemulsion are modified. The oil phase droplets of the MOIW microemulsion are modified with alcohol and can solubilize oil-soluble species, including | 2022-07-28 |
20220233442 | COMPOSITIONS OF BUPIVACAINE MULTIVESICULAR LIPOSOMES - Embodiments of the present application relate to compositions of multivesicular liposomes (MVLs) and commercial manufacturing processes for making bupivacaine MVLs. | 2022-07-28 |
20220233443 | PRODUCTION AND USE OF EXTRACELLULAR VESICLE-CONTAINED ENAMPT - The present invention relates to various compositions comprising NAMPT and/or mutant thereof, processes for preparing these compositions, and various methods of using these compositions to prevent or treat an age-associated condition in a subject. The present invention also relates to methods of increasing NMN and/or NAD+ biosynthesis in a cell. | 2022-07-28 |
20220233444 | THIOESTER CATIONIC LIPIDS - The present invention provides, in part, thioester cationic lipid compounds of formula A, and sub-formulas thereof: or a pharmaceutically acceptable salt thereof. The compounds provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly can be useful for treating various diseases, disorders and conditions, such as those associated with deficiency of one or more proteins. | 2022-07-28 |
20220233445 | FUSOGENIC COMPOUNDS FOR DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES - Fusogenic compounds, and compositions and methods of use thereof. The fusogenic compounds can be used for making nanoparticle compositions for use in biopharmaceuticals and therapeutics. More particularly, compounds, compositions and methods are to provide nanoparticles to incorporate or encapsulate active agents, to deliver and distribute the active agents to cells, tissues, organs, and subjects. | 2022-07-28 |
20220233446 | MANUFACTURING OF BUPIVACAINE MULTIVESICULAR LIPOSOMES - Embodiments of the present application relate to commercial manufacturing processes for making bupivacaine multivesicular liposomes (MVLs) using independently operating dual tangential flow filtration modules. | 2022-07-28 |
20220233447 | MANUFACTURING OF BUPIVACAINE MULTIVESICULAR LIPOSOMES - Embodiments of the present application relate to batches of bupivacaine multivesicular liposomes (MVLs) prepared by a commercial manufacturing process using independently operating dual tangential flow filtration modules. | 2022-07-28 |
20220233448 | MANUFACTURING OF BUPIVACAINE MULTIVESICULAR LIPOSOMES - Embodiments of the present application relate to batches of bupivacaine multivesicular liposomes (MVLs) prepared by a commercial manufacturing process using independently operating dual tangential flow filtration modules. | 2022-07-28 |
20220233449 | SOLID DISPERSION AND PREPARATION METHOD THEREFOR - Solid dispersion and a preparation method therefor. In a specific embodiment, the solid dispersion contains an active ingredient (R)-4-amino-1-(1-(but-2-ynyl)pyrrolidin-3-yl))-3-(4-(2,6-difluorophenoxy)phenyl)-1,6-dihydro-7H-pyrrolo[2,3-d]pyridazin-7-one or a salt thereof, and a carrier material, and the pH value is adjusted; employing a method that adds an appropriate amount of acid effectively inhibits an emulsification phenomenon in a reverse solvent process, thereby obtaining solid dispersion having a moderate particle size and uniform content. | 2022-07-28 |