30th week of 2011 patent applcation highlights part 39 |
Patent application number | Title | Published |
20110183346 | COMPOSITIONS FOR USE IN IDENTIFICATION OF NEISSERIA, CHLAMYDIA, AND/OR CHLAMYDOPHILA BACTERIA - The present invention relates generally to the detection and identification of | 2011-07-28 |
20110183347 | Compositions and methods for therapeutic delivery with microorganisms - Certain embodiments disclosed relate to compositions, including therapeutic compositions, methods, devices, and systems that include modified microorganisms including at least one genetic element encoding at least one therapeutic agent or environmental treatment agent. | 2011-07-28 |
20110183348 | Compositions and methods for therapeutic delivery with microorganisms - Certain embodiments disclosed relate to compositions, including therapeutic compositions, methods, devices, and systems that include modified microorganisms including at least one genetic element encoding at least one therapeutic agent or environmental treatment agent. | 2011-07-28 |
20110183349 | BIOMARKERS FOR IgA NEPHROPATHY AND APPLICATIONS THEREOF - The present invention provides a method for diagnosis or prognosis of IgA nephropathy in a subject based on detection of the expression level of one or more biomarker genes selected from the group consisting of thymosin β4 (Tmsb4), serine or cysteine proteinase inhibitor clade E member 2 (Serpine2), secreted phosphoprotein 1 (OPN), butyrophilin-like-2 (BTNL2), S100 calcium binding protein A8 (S100A8), Cystatin C (CysC), and any combination thereof. | 2011-07-28 |
20110183350 | METHOD FOR SELECTING SECONDARY NEUROSPHERE DERIVED FROM DIFFERENTIATED CELL-DERIVED PLURIPOTENT STEM CELL, CLONE SELECTED BY THE METHOD AND USE OF THE CLONE - In order to provide a therapeutic agent for nerve injury which contains iPS-derived neural stem cells and has low or no risk of side effects, as well as a method for treating a nerve injury using the iPS cells, by efficiently establishing in vivo the iPS-derived neural stem having low or no risk of tumor formation, neurospheres are formed following formation of embryoid bodies from the iPS cells, and a clone whose ratio of cells in which the promoter of Nanog gene is activated is 0.01% or less is selected, and the clone is administered to a patient suffering from the nerve injury. | 2011-07-28 |
20110183351 | Compositions and methods for therapeutic delivery with microorganisms - Certain embodiments disclosed relate to compositions, including therapeutic compositions, methods, devices, and systems that include modified microorganisms including at least one genetic element encoding at least one therapeutic agent or environmental treatment agent. | 2011-07-28 |
20110183352 | Configurable Diagnostic Systems and Methods for Performing Assays - A method and system for configuring an analyzer is disclosed. The analyzer receives a strip identifier from a strip or a vial identifier from a vial. The parameter module in the analyzer determines the parameters corresponding to the received strip identifier or the vial identifier. The parameter module then configures the analyzer to perform a test with the strip using the determined parameters. In one embodiment, the diagnostic test module determines the test corresponding to the received strip identifier or the vial identifier and the diagnostic test module configures the analyzer to perform the determined test with the strip. In another embodiment, the association determination module determines if the received strip identifier and vial identifier are associated with each other. If not, the analyzer renders an error requesting a correct strip. | 2011-07-28 |
20110183353 | COMPOSITION AND METHOD FOR DIAGNOSING FUNGAL DISEASE - Methods of diagnosing a fungal infection using anti-glycan antibodies alone or in combination with other anti-fungal diagnostic tests are described. Laminaribioside and chitobioside are used as antigens to detect human antibodies. | 2011-07-28 |
20110183354 | HUMAN Fc GAMMA RECEPTOR III - The present invention relates to the field of human immunoglobulin receptors, specifically the glycostructure of a human Fc gamma receptor IIIa recombinantly expressed in human embryonic kidney cells and Chinese hamster ovary cells. | 2011-07-28 |
20110183355 | POLYMER PARTICLE CONTAINING FLUORESCENT MOLECULE AND METHOD FOR PRODUCING THE SAME - Polymer particles are provided which contain fluorescent molecules with high presence ratio in a polymer layer thereof and a method for preparing thereof. Polymer particles are swelled in a non-aqueous solution excluding exclusively water preferably promotes selling of the polymer layer and transfer of the fluorescent molecules to the polymer layer could not protected by water molecules such that much more fluorescent molecule may be introduced into inside of the polymer layer. Furthermore, since the water is added to the reaction system prior to evaporation removal of the non-aqueous solvent, dry-up of the polymer particles is prevented by the water remained in the reaction system and the polymer particles including fluorescent molecules with high presence ratio of the fluorescent molecules preferably keep high dispersibility using the above described procedures. | 2011-07-28 |
20110183356 | METHOD TO IDENTIFY PATIENTS AT RISK FOR LUNG TRANSPLANT REJECTION - Various embodiments include methods for diagnosing and treating medical conditions that involve an autoimmune response to connective tissue such as collagen found in organs such as the lung. In one method pulmonary disease and disorders such as Idiopathic Pulmonary Fibrosis (IPF) are diagnosed by analyzing fluid or tissue samples obtained from a patient for evidence of an autoimmune response to various types of collagen including, for example, Type V. One type of assay for evidence of an autoimmune response to Type V collagen comprises the steps of obtaining a fluid or tissue sample from a patient, contacting at least a portion of the sample with antigen to anti-Type V collagen antibody and monitoring the mixture of sample and antigen for changes indicative of the presence of anti-Type V collagen in the sample. Another embodiment includes treating pulmonary diseases such as IPF by administering a therapeutically effective dose of epitopes of various collagens including Type V collagen. | 2011-07-28 |
20110183357 | DEVICE AND METHODS FOR LIQUID CRYSTAL-BASED BIOAGENT DETECTION - The present invention provides liquid crystal-based devices and methods for bioagent detection. In certain aspects, the present invention is directed to devices and methods utilizing liquid crystals and membranes containing polymerized targets that can report the presence of bioagents including, but not limited to, enzymes, antibodies, and toxins. | 2011-07-28 |
20110183358 | METHODS AND COMPOSITIONS FOR DEREPRESSION OF IAP-INHIBITED CASPASE - The invention provides isolated agents having novel chemical structures and possessing superior activity as derepressors of IAP inhibited caspase. The invention further provides a method of derepressing an IAP-inhibited caspase. The invention further provides assay methods employing labeled compounds of the invention, especially fluorescent labeled compounds. | 2011-07-28 |
20110183359 | METHODS FOR DETECTING MODULATORS OF CYTOKINE RECEPTOR ZALPHA11 - Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zalpha11, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zalpha11, are located on chromosome 16, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto. | 2011-07-28 |
20110183360 | ANTIBODIES TO CLOSTRIDIUM DIFFICILE SPORES AND USES THEREOF - The present invention provides antibodies that bind to the endospore of the bacterium | 2011-07-28 |
20110183361 | Nonseparation Assay Methods - Assay methods are disclosed involving specific binding reactions which are simplified compared to known methods. A compound capable of producing chemiluminescence is immobilized on a solid support as is a member of a specific binding pair for capturing an analyte from a sample. An activator compound that activates the chemiluminescent compound and is conjugated to a specific binding pair member is added in excess along with the sample to the solid support. Addition of a trigger solution causes a chemiluminescent reaction at the sites where the activator conjugate has been specifically bound. The assay methods are termed non-separation assays because they do not require removal or separation of excess detection label (activator conjugate) prior to the detection step. The methods are applicable to various types of assays including immunoassays, receptor-ligand assays and nucleic acid hybridization assays. | 2011-07-28 |
20110183362 | COMPOSITIONS AND METHODS FOR MEASURING LEVELS OF BIOACTIVE HUMAN HEPCIDIN - The invention provides compositions and methods for measuring human serum hepcidin levels. The invention provides methods for the oxidative refolding of a hepcidin polypeptide to a form that is mature, bioactive and folded as in the native configuration and molecular mass; a method for measuring the level of native, bioactive hepcidin in a vertebrate animal. | 2011-07-28 |
20110183363 | ASSAYS FOR DETECTING ANTIBODIES SPECIFIC TO THERAPEUTIC ANTI-IGE ANTIBODIES AND THEIR USE IN ANAPHYLAXIS - The invention provides methods and reagents useful for detecting anti-drug antibodies of IgE isotype to therapeutic anti-IgE antibodies, and methods for assessing risk of anaphylaxis to administration of a therapeutic anti-IgE antibody. | 2011-07-28 |
20110183364 | ANALYTICAL METHOD FOR THE DETECTION OF LATENT HEPATITIS C, USE THEREOF AND CORRESPONDING DIAGNOSIS KIT - The invention relates to an improved analytical method for the detection of latent hepatitis C, to the use thereof and to the corresponding diagnosis kit. The analytical method is based on the immunoassay technique and the most suitable operating conditions for detecting latent hepatitis C have been determined. The invention also relates to a diagnosis kit complementary to the method. The invention is suitable for use in medicine, biomedical research and in the field of analytical techniques. | 2011-07-28 |
20110183365 | Thrombin Generation Determination Method - A method for measuring a generation of thrombin in a sample of whole blood as a function of time includes adding to a sample of whole blood a fluorogenic substrate and a thrombin activator to form an activated sample. A conversion product is permitted to form in the activated sample. Fluorescence is measured as a function of time from a fluorescent group that is released during the formation of the conversion product with the use of a fluorescence detector. The fluorescence detector operates in an extended range mode and has an increased sensitivity. Thrombin generation as a function of time can then be calculated from the measured fluorescence as a function of time. | 2011-07-28 |
20110183366 | Methods for achieving a protective ACE2 expression level to treat kidney disease and hypertension - The present invention provides a method for enhancing expression of angiotensin converting enzyme ACE2 in the vasculature of a mammal, particularly in the renal vasculature and podocytes. The method comprises administering to a mammal in need of such enhancement (e.g., a mammal suffering from, or at risk of developing renal damage or hypertension), an amount of an angiotensin II antagonist sufficient to promote a protective level of ACE2 expression in the vasculature of the mammal. Preferably, the angiotensin II antagonist is administered in an angiotensin II blocking amount, more preferably in an amount sufficient to achieve and maintain a desired level of ACE2 expression in the vasculature of the mammal. The methods of the invention are useful for ameliorating kidney damage from diseases, such as diabetes, as well as hypertension. | 2011-07-28 |
20110183367 | DEVICE AND METHOD FOR NON-INVASIVE MEASUREMENT OF THE INDIVIDUAL METABOLIC RATE OF A SUBSTANTIALLY SPHERICAL METABOLIZING PARTICLE - The present invention relates to methods and devices for non-invasive and non-disturbing measurements of metabolizing rates of substantially spherical metabolizing particles, such as an embryo, and to a method and device for controlling oxygen partial pressure at the level of the embryo. Furthermore, the invention relates to a method for regulating supply of metabolites to a substantially spherical metabolizing particle, as well as a method for selecting substantially spherical metabolizing particles of a predetermined quality. The invention is carried out in a device capable of establishing a diffusion gradient of metabolites between the substantially spherical metabolizing particle inside a compartment in the device and the environment outside the compartment. The metabolizing rate is determined based on information of the metabolite diffusion gradient. | 2011-07-28 |
20110183368 | METHOD AND APPARATUS FOR USING LIGHT EMITTING DIODES IN A GREENHOUSE SETTING - There is provided a modular LED system comprising a frame ( | 2011-07-28 |
20110183369 | PLANT INFESTING SYSTEMS AND METHODS - The present disclosure provides systems and methods for infesting the roots of a plant with larval insects. In various embodiments, an exemplary method includes injecting an egg solution into a root zone of the plant, wherein the root zone is disposed within a planting media of the plant. | 2011-07-28 |
20110183370 | OPTICAL IMAGING FOR IDENTIFYING CELLS LABELED WITH FLUORESCENT NANOPARTICLES - An optical detection system for identifying target bacterial cells in a food sample, comprising a first fluorescent nanoparticle dye labeling specifically the target cells. A second fluorescent dye reacts non-specifically with all bacterial cells. An imaging unit optically excites the fluorescent dyes and captures images of the sample for each of two different wavelength bands emitted as a result of the excitation of the dyes. A processing unit identifies the target cells from the sample and comprises an image processing unit for processing the images of the sample. A target cell identifier identifies the target cells in the images by detecting individual units present at a same location in both of the processed images. An output unit provides data related to the identified target cells in the sample. A method is also provided. | 2011-07-28 |
20110183371 | MICROBE-COLLECTING CARRIER CARTRIDGE, CARRIER TREATING APPARATUS, AND METHOD OF MEASURING MICROBES - A disposable microbe-collecting carrier cartridge and a carrier treating apparatus which efficiently convert microbes collected on a carrier into a solution and prevent variations in the amount of retrieval of microbes upon concentration on a filter are provided. A cartridge formed of an upper lid having a plurality of through holes, a container in an inverted-cone shape having both of a liquid storage sink unit having a filter at the bottom and an air suction path, and a support base for setting up a thermoplastic carrier, such as gelatin, and a carrier treating apparatus formed of a dispensing nozzle for liquid supply, a liquid supply mechanism, a liquid heating mechanism, and a suction pump for filtration are prepared. Warm water is supplied onto the filter set up on a bottom surface of the inverted-cone-shaped container and is stored in the liquid storage sink, thereby causing the carrier to make contact with the warm water. The contact with the warm water causes the carrier to be solated, and mixed and diluted with the warm water. Then, the suction pump of the filtration device is activated for suction and filtration of the mixed liquid through the filter. By using the filter having a shape not allowing microbes to pass through and having a gap, only microbes are captured on the filter after suction and filtration. Polymers and dust to be a background upon an ATP measurement pass through the filter by filtration to be cleanly eliminated. | 2011-07-28 |
20110183372 | STIMULATED CELL STANDARDS - Methods for producing stimulated, positive and negative control reference standard for monitoring intracellular cytokine levels and cytokine release in test samples by stimulating cells to produce cytokines in the presence of a cytokine release inhibitor, fixing the stimulated cells with a fixative such as paraformaldehyde, washing to remove excess fixatives and freeze-drying the stimulated, fixed cells. Methods for producing labeled reference standards for cell proliferation assays are also disclosed, in which proliferation-competent mammalian cells, isolated from a human or animal body are labeled with a label, such as a dye, that is divided between daughter cells during cell proliferation (e.g., carboxyfluorescein succinimidyl ester), the cells are stimulated to proliferate, the proliferated cells are fixed by addition of a fixative and then preserved by freeze drying or cryopreservation. | 2011-07-28 |
20110183373 | RECOMBINANT PEPTIDE PRODUCTION USING A CROSS-LINKABLE SOLUBILITY TAG - The invention relates to the recombinant expression of a peptide of interest in the form of a fusion protein comprising a solubility tag. The fusion protein comprises at least two portions separated by a cleavable peptide sequence wherein one portion is devoid of cysteine residues and the second portion comprises an effective number of cross-linkable cysteine residues. After cell lysis and isolation of the fusion protein, the fusion protein is subsequently cleaved into a mixture of first and second portions. Oxidative cross-linking is used to selectively precipitate one of the two portions to facilitate simple and effective separation of the peptide of interest. | 2011-07-28 |
20110183374 | THIOPEPTIDE PRECURSOR PROTEIN, GENE ENCODING IT AND USES THEREOF - The present invention relates to the precursor proteins for thiopeptide biosynthesis, and the corresponding structural genes and uses thereof. The present invention also relates to methods for genetically manipulating the thiopeptide precursor protein or host cells expressing a gene encoding said thiopeptide precursor protein to produce thiopeptide compounds or their derivatives. The present invention further relates to the cloning and characterization of genes involved in thiopeptide biosynthesis and their use in thiopeptide compounds production. | 2011-07-28 |
20110183375 | METAL BINDING COMPOUNDS AND THEIR USE IN CELL CULTURE MEDIUM COMPOSITIONS - The present invention is directed generally to metal binding compounds which may be added to cell culture media to replace factors required for cultivation of the cells (e.g. transferrin) which are of animal or human origin. More specifically, the invention is directed to metal binding compounds or complexes thereof comprising one or more transition element cations (such as ferrous or ferric ions), which are added to cell and tissue culture medium compositions. The metal binding compounds may be added to the media alone or may be first complexed with a transition metal ion. The invention is also directed to methods of use of such compositions, including, for example, methods for the cultivation of eukaryotic cells, particularly animal cells, in vitro. The invention also relates to compositions comprising such culture media and one or more cells, and to kits comprising one or more of the above-described compositions. The compositions of the present invention obviate the need for naturally derived metal-binding proteins, such as transferrin and ceruloplasmin, which may contain blood-borne pathogens. | 2011-07-28 |
20110183376 | NOVEL ANTI-IGF-IR ANTIBODIES AND USES THEREOF - The present invention relates to novel antibodies capable of binding specifically to the human insulin-like growth factor I receptor IGF-IR and/or capable of specifically inhibiting the tyrosine kinase activity of said IGF-IR receptor, especially monoclonal antibodies of murine, chimeric and humanized origin, as well as the amino acid and nucleic acid sequences coding for these antibodies. The invention likewise comprises the use of these antibodies as a medicament for the prophylactic and/or therapeutic treatment of cancers overexpressing IGF-IR or any pathology connected with the overexpression of said receptor as well as in processes or kits for diagnosis of illnesses connected with the overexpression of the IGF-IR receptor. The invention finally comprises products and/or compositions comprising such antibodies in combination with anti-EGFR antibodies and/or compounds and/or anti-cancer agents or agents conjugated with toxins and their use for the prevention and/or the treatment of certain cancers. | 2011-07-28 |
20110183377 | METHODS, SYSTEMS AND REAGENTS FOR IMPROVED IMMUNODETECTION - The instant invention provides methods, systems and reagents for immunodetection involving novel epitope tags and antibodies which recognize these new epitope tags as well as the antibodies which detect the FLAG epitope tag. Fusion proteins comprising the epitope tags, as well as methods of purifying these proteins and kits detecting these proteins are also provided. | 2011-07-28 |
20110183378 | NUCLEIC ACID AMPLIFICATION METHOD, NUCLEIC ACID AMPLIFICATION APPARATUS, AND CHIP USED IN NUCLEIC ACID AMPLIFICATION - A nucleic acid amplification method includes introducing a liquid sample into a first chamber of a chip for use in nucleic acid amplification, the chip including a second chamber containing liquid that has a smaller specific gravity than the liquid sample and is immiscible with the liquid sample, injecting the liquid sample into the second chamber from the first chamber by a centrifugal force, regulating a temperature of an end of the chip, and rotating the chip about a rotation axis at a predetermined speed. | 2011-07-28 |
20110183379 | FLOW PROCESS FOR PRETREATMENT OF LIGNOCELLULOSIC BIOMASS - Described are methods for pretreating lignocellulosic biomass that comprise thermally conditioning the biomass by flow processing an aqueous slurry of the biomass through an outer passage(s) of one or more heat exchange devices while circulating a heat exchange fluid through an inner passage(s) of the heat exchange device(s). Also described are methods for producing fermentation products, especially ethanol, from the pretreated biomass. | 2011-07-28 |
20110183380 | POROUS, CARBOHYDRATE-BASED FOAM STRUCTURES AND ASSOCIATED METHODS - Porous, carbohydrate-based foam structures and associated methods are disclosed. According to an aspect, a method can include using a starch solution. The starch solution can be precipitated to form starch nanoparticles having a predefined void structure. | 2011-07-28 |
20110183381 | THERMOCELLULASES FOR LIGNOCELLULOSIC DEGRADATION - Thermostable cellulase enzyme systems comprising at least one each of a thermostable endoglucanase, an exo-processive-endoglucanase, and a β-glucosidase carry out the complete, coordinated hydrolysis of crystalline cellulose to monomeric glucose. | 2011-07-28 |
20110183382 | METHODS AND COMPOSITIONS FOR PRODUCING CHEMICAL PRODUCTS FROM C. PHYTOFERMENTANS - This invention provides systems and methods for the production of compounds by | 2011-07-28 |
20110183383 | Compositions and Methods of Producing Methionine - Described herein are microorganisms that produce methionine and related products from endogenous genes in a transsulfuration pathway, as well as from exogenous genes providing a direct sulfhydrylation pathway. Novel genes that are useful for methionine and SAMe production are disclosed. | 2011-07-28 |
20110183384 | RECOMBINANT BACTERIA FOR PRODUCING DEOXYVIOLACEIN AND USES THEREOF - Recombinant bacteria for producing deoxyviolacein and uses thereof are provided, wherein the recombinant bacteria is obtained by introducing the deoxyviolacein synthesis-related gene cluster into | 2011-07-28 |
20110183385 | METHOD OF EXTRACTION AND YIELD-UP OF TRICYCLO COMPOUNDS BY ADDING A SOLID ADSORBENT RESIN AS THEIR CARRIER IN FERMENTATION MEDIUM - The present invention relates to a method of fermenting and purifying tricyclo compounds, specifically FK506 and/or FK520, and more particularly, to a method of purifying tricyclo compounds by adding a hydrophobic absorbent resin as a carrier in culturing FK506 and/or FK520 producing bacteria. | 2011-07-28 |
20110183386 | PREPARATION OF EPSILON-CAPROLACTAM FROM (Z)-6,7-DIHYDRO-1H-AZEPIN-2(5H)-ONE - The invention relates to a method for preparing ε-caprolactam comprising reducing the carbon-carbon double bond of (Z)-6,7-dihydro-1H-azepin-2(5H)-one, wherein the reduction is catalysed by a biocatalyst. The invention further relates to a novel host cell comprising a biocatalyst capable of catalysing said reduction and to a novel polynucleotide encoding a biocatalyst capable of catalysing said reduction. | 2011-07-28 |
20110183387 | New Mutant Yeast Strains Capable of Accumulating a Large Quantity of Lipids - The subject of the present invention is a novel mutant yeast strain, particularly a | 2011-07-28 |
20110183388 | Extracellular Polyhydroxyalkanoates Produced By Genetically Engineered Microorganisms - The present invention is in the field of biosynthesis of polyhydroxyalkanoates (PHA). The invention relates to a genetically engineered microorganism having at least one gene involved in the metabolism, preferably in the production, of polyhydroxyalkanoates (PHA). This microorganism is useful in commercial production of polyhydroxyalkanoates. The present invention further relates to a method for the production of polyhydroxyalkanoates (PHA). | 2011-07-28 |
20110183389 | PRODUCTION OF LACTIC ACID FROM HEMICELLULOSE EXTRACTS - A method is provided for producing lactic acid comprising fermenting sugars derived from biomass using sugar consuming bacteria to produce lactic acid. In certain embodiments, the biomass is woody biomass, and the bacteria are pentose consuming bacteria such as | 2011-07-28 |
20110183390 | Method of Conversion of Syngas Using Microorganism on Hydrophilic Membrane - A stable system for producing liquid products such as ethanol, butanol and other chemicals from syngas components contacts CO or a mixture of CO | 2011-07-28 |
20110183391 | Biosynthesis of Phloroglucinol and Preparation of 1,3-Dihydroxybenzene Therefrom - The present invention provides methods, enzymes, and cells for the biosynthetic production of phloroglucinol from malonyl-CoA, which is ultimately obtained from simple starting materials such as glucose; also provided are methods for preparing derivatives of biosynthetic phloroglucinol, including, e.g., resorcinol. | 2011-07-28 |
20110183392 | YEAST ORGANISM PRODUCING ISOBUTANOL AT A HIGH YIELD - There is disclosed a method of producing isobutanol. In an embodiment, the method includes providing a microorganism transformed with an isobutanol producing pathway containing at least one exogenous gene. The microorganism is selected to produce isobutanol from a carbon source at a yield of at least 10 percent theoretical. The method includes cultivating the microorganism in a culture medium containing a feedstock providing the carbon source, until isobutanol is produced. The method includes recovering the isobutanol. In one embodiment, the microorganism is a yeast with a Crabtree-negative phenotype. In another embodiment, the microorganism is a yeast microorganism with a Crabtree-positive phenotype. There is disclosed a microorganism for producing isobutanol. In an embodiment, the microorganism includes an isobutanol producing pathway containing at least one exogenous gene, and is selected to produce a recoverable quantity of isobutanol from a carbon source at a yield of at least 10 percent theoretical. | 2011-07-28 |
20110183393 | METHODS OF INCREASING DIHYDROXY ACID DEHYDRATASE ACTIVITY TO IMPROVE PRODUCTION OF FUELS, CHEMICALS, AND AMINO ACIDS - The present invention is directed to recombinant microorganisms comprising one or more dihydroxyacid dehydratase (DHAD)-requiring biosynthetic pathways and methods of using said recombinant microorganisms to produce beneficial metabolites derived from said DHAD-requiring biosynthetic pathways. In various aspects of the invention, the recombinant microorganisms may be engineered to overexpress one or more polynucleotides encoding one or more Aft proteins or homologs thereof. In some embodiments, the recombinant microorganisms may comprise a cytosolically localized DHAD enzyme. In additional embodiments, the recombinant microorganisms may comprise a mitochondrially localized DHAD enzyme. In various embodiments described herein, the recombinant microorganisms may be microorganisms of the | 2011-07-28 |
20110183394 | METHOD OF PRODUCING YEAST BIOMASS - The invention relates to use of a substrate comprising C5 compound-containing material, in the growth of | 2011-07-28 |
20110183395 | PROCESSES FOR PRODUCING A FERMENTATION PRODUCT - The present invention relates to processes for producing a fermentation product, such as ethanol, from milled starch-containing material comprising (a) saccharifying the milled starch-containing material with a glucoamylase having an amino acid sequence shown in SEQ ID NO: 2, or a glucoamylase being at least 70% identical thereto, at a temperature below the initial gelatinization temperature of said starch-containing material, (b) fermenting using a fermenting organism. | 2011-07-28 |
20110183396 | PRODUCTION AND USE OF YEAST HAVING INCREASED CELLULOSE HYDROLYSIS ABILITY - The present invention provides a method for producing an yeast having an increased cellulose hydrolysis ability. The method includes the step of introducing increased integration copy numbers of both a gene for an enzyme capable of hydrolyzing crystalline cellulose and a gene for an enzyme capable of hydrolyzing noncrystalline cellulose into a noncellulolytic yeast to give a transformed yeast. The yeast having an increased cellulose hydrolysis ability can be suitably used for ethanol production from cellulose-based materials. | 2011-07-28 |
20110183397 | Carbonic Anhydrase Bioreactor and Process - A triphasic bioreactor for physico-chemically treating a gas is disclosed. The triphasic bioreactor comprises a reaction chamber with a liquid and biocatalysts in suspension in the liquid, for catalyzing a reaction between the gas and the liquid to obtain a treated gas and a solution containing a reaction product. A gas bubbling means is provided in the reaction chamber for bubbling the gas to be treated into the liquid thereby dissolving the gas into the liquid and increasing a pressure inside the reaction chamber. The bioreactor further comprises a liquid inlet in fluid communication with the reaction chamber for receiving the liquid and filling the reaction chamber, a liquid outlet in fluid communication with the reaction chamber for releasing the solution and a gas outlet in fluid communication with the reaction chamber to release the treated gas. The bioreactor further comprises a retention device to retain the biocatalysts in the reaction chamber. The invention also concerns a process using the triphasic bioreactor. The triphasic bioreactor may advantageously be used for removing carbonic dioxide from a CO | 2011-07-28 |
20110183398 | MICROORGANISM-CAPTURING COMPOSITIONS AND METHODS - The invention relates to compositions, methods, devices, and kits for non-specifically isolating bacterial cells. The compositions comprise a solid support which has a surface comprising a combination of a carbohydrate and a biotin-binding protein, wherein the protein is covalently bonded to the carbohydrate, and wherein the protein is linked to the solid support via the carbohydrate; and at least one of 1) a plurality of bacterial cells non-specifically bound to the combination of the carbohydrate and the protein or 2) an amphiphilic glycoside of a steroid or triterpene. The methods, devices, and kits include at least one of these compositions. | 2011-07-28 |
20110183399 | Maize Cellulose Synthases and Uses Thereof - The invention provides isolated cellulose synthase nucleic acids and their encoded proteins. The present invention provides methods and compositions relating to altering cellulose synthase levels in plants. The invention further provides recombinant expression cassettes, host cells, and transgenic plants comprising said nucleic acids. | 2011-07-28 |
20110183400 | PROCESS FOR PRODUCTION OF LIPASES BY GENETIC MODIFICATION OF YEAST - The present invention relates to the construction of optimized synthetic lipase gene expression vectors for the high level expression of recombinant lipases in the yeast. The invention provides an enzymatic approach to the industrial processing of by-products resulting from biodiesel production. | 2011-07-28 |
20110183401 | Kappa-Carrageenase And Kappa-Carrageenase-Containing Compositions - The present invention provides cleaning compositions comprising at least one carrageenase enzyme, methods for producing carrageenase enzymes in host cells, host cells comprising recombinant polynucleotides encoding at least one carrageenase, and recombinant polynucleotides encoding carrageenase. | 2011-07-28 |
20110183402 | Methods of synthesizing heteromultimeric polypeptides in yeast using a haploid mating strategy - Methods are provided for the synthesis and secretion of recombinant proteins preferably large mammalian proteins or hetero-multimeric proteins at high levels and for prolonged time in polyploid, preferably diploid yeast. These methods use various mating competent yeast, including | 2011-07-28 |
20110183403 | CELL DISRUPTION OF PLANT AND ANIMAL RAW MATERIALS BY A COMBINATION OF AUTOMIZATION PROCESS WITH DECOMPRESSION PROCESSES FOR SELECTIVE EXTRACTION AND SEPARATION OF INTERACELLULAR VALUABLE SUBSTANCES - A method for cell disruption of biogenic suspended raw materials by means of a combination of pressurization, atomization and decompression with a subsequent selective extraction and separation of cellular valuable substances includes at least one reservoir cubicle serving as reservoir for a suspension composed of biogenic raw material and at least another reservoir cubicle utilized as reservoir for a solvent. A cellular extract is produced in one unit for cell disruption, and is subsequently flown through by a gas in an extraction stage. The gas burdened with cellular valuable substances is separated from the cellular valuable substances in a separation stage by lowering the pressure. The suspension includes biogenic raw material pressurized to a pressure of 100-2500 bar by a device for pressure boosting. The solvent is pressurized to a pressure of 100-2500 bar by a device for pressure boosting. The solvent and the suspension are brought together in one line at a pressure of 100-2500 bar and mixed to a solution mixture which is atomized through at least one jet at a pressure of 100 to 2500 bar and a temperature of 10 to 90° C. into a cubicle with a lower pressure. | 2011-07-28 |
20110183404 | METHOD FOR PROCESSING PORCINE CORNEA FOR DECELLULARIZATION - Disclosed is a method for processing porcine cornea using an aqueous NaCl solution and an aqueous trypsin/EDTA solution to decellularize enucleated porcine cornea. The porcine cornea processed by the method causes neither inflammation nor immune rejection. The porcine corneal stroma decellularized by the method can be recellularized together with host keratocytes after transplantation. | 2011-07-28 |
20110183405 | MODIFIED MULTIWELL PLATE FOR BIOCHEMICAL ANALYSES AND CELL CULTURE EXPERIMENTS. - The invention relates to a modified multi-well plate for biochemical analyses and cell culture experiments, which can be obtained through a method for functionalization. The method comprises the following process steps:
| 2011-07-28 |
20110183406 | Apparatus For Separating Tissue Cells From A Fluid - The invention relates to an apparatus for separating tissue cells from a fluid, with a collection container forming a collection space, which is connected, on one hand, with a negative pressure source and which is connected, on the other hand, with a supply line for the fluid-tissue cell mixture. | 2011-07-28 |
20110183407 | APPARATUS AND METHOD FOR TIP ALIGNMENT IN MULTIWELL PLATES - Apparatuses and methods of aligning at least one tip of a tip manifold with a plurality of wells of a multiwell plate. The tip manifold includes a plate, at least one tip depending from the plate, a first tip alignment pin depending from the plate, and a second tip alignment pin depending from the plate. The second tip alignment pin opposes the first tip alignment pin. The multiwell plate includes a body defining a plurality of non-porous wells for holding biological material, a first alignment hole, and a second alignment hole. The second alignment hole opposes the first alignment hole. | 2011-07-28 |
20110183408 | REAGENT CARTRIDGE FOR MICROORGANISM DETECTION APPARATUS - A reagent cartridge for a microorganism detection apparatus includes a plurality of reagent vessels, a support plate, and side plates, wherein the reagent vessels are integrally connected with each other in parallel by the support plate, and a group of the plurality of the reagent vessels is surrounded by the side plates; the reagent cartridge further includes an independent reagent vessel instead of at least one of the plurality of the reagent vessels and separately therefrom; and an engagement portion, wherein the engagement portion engages the independent reagent vessel in the engagement portion so as to be universally attached and detached, and to be in parallel with the plurality of the reagent vessels. | 2011-07-28 |
20110183409 | SEALED CHIP PACKAGE - The invention provides environmental packages, instruments, and methods for sealing, protecting, and providing analysis chips for processing and analysis. The analysis chips are bonded directly or indirectly to chip carriers which are held within the chambers of an environmental packaging strip. The chambers are sealed with a sealing film such that the chip carriers can be extracted using a piercing tool and an extraction tool. | 2011-07-28 |
20110183410 | BIOMASS POWER PLANT - The invention relates to a biomass power plant for dry-wet simultaneous fermentation, having dry fermenter modules comprising dry fermenters. In order to refine the biomass power plant such that the length of the pipes for delivering process water is reduced to a minimum, the invention proposes to integrate a process water reservoir between two dry fermenter modules. | 2011-07-28 |
20110183411 | SELF-STERILIZING AUTOMATED INCUBATOR - A method and system for self-sterilizing an automated incubator is disclosed. The internal temperature of the automated incubator is elevated by forcing hot air to flow into the internal incubation chamber, wherein all mechanics and electronics associated with the automated plate mover are outside the internal incubation chamber. During sterilization, the heating system of the automated incubator will force hot air to flow over the internal surfaces of the incubator, thereby reducing contaminating microorganism resistance by inducing dehydration. | 2011-07-28 |
20110183412 | ALTERATION OF FC-FUSION PROTEIN SERUM HALF-LIVES BY MUTAGENESIS - The present invention provides for a modified Fc-fusion protein in which at least one amino acid from the heavy chain constant region selected from the group consisting of amino acid residues 250, 314, and 428 is substituted with another amino acid which is different from that present in the unmodified Fc-fusion protein, thereby altering the binding affinity for FcRn and/or the serum half-life in comparison to the unmodified Fc-fusion protein. | 2011-07-28 |
20110183413 | Biologically active C-terminal arginine-containing peptides - The present invention concerns the separation, identification and characterization of active peptide fragments from peptones. | 2011-07-28 |
20110183414 | Expansion Medium for CD34-Negative Stem Cells - This invention provides a cell growth medium comprising (a) a human platelet lysate free of solid matter greater than 0.22 μm in diameter, wherein the lysate constitutes from 2% to 15% of the total volume of the cell growth medium; (b) a human fresh frozen plasma (FFP) filtrate free of solid matter greater than 0.22 μm in diameter, wherein the FFP filtrate constitutes from 1% to 10% of the total volume of the cell growth medium; (c) heparin at a concentration of from 0 U/ml to 10 U/ml of the cell growth medium; (d) L-glutamine at a concentration of from 0.5 mM to 10 mM; and (e) a serum-free, low glucose medium suitable for mammalian cell growth, wherein the serum-free, low glucose medium constitutes from 75% to 97% of the total volume of the cell growth medium, and may contain the L-glutamine of part (d); wherein the cell growth medium permits the expansion of human CD34 | 2011-07-28 |
20110183415 | DERIVATION OF EMBRYONIC STEM CELLS AND EMBRYO-DERIVED CELLS - This present invention provides novel methods for deriving embryonic stem cells and embryo-derived cells from an embryo without requiring destruction of the embryo. The invention further provides cells and cell lines derived without embryo destruction, and the use of the cells for therapeutic and research purposes. It also relates to novel methods of establishing and storing an autologous stem cell line prior to implantation of an embryo, e.g., in conjunction with reproductive therapies such as IVF. | 2011-07-28 |
20110183416 | Method of modulating the proliferation of medullary thyroid carcinoma cells - The present invention is directed to a method of decreasing the rate of proliferation of medullary thyroid carcinoma cells which comprises contacting medullary thyroid carcinoma cells with one or more SSTR2 agonist. A preferred selective somatostatin receptor type-2 (SSTR-2) agonist cyclo[Tic-Tyr-D-Trp-Lys-Abu-Phe] is also disclosed. | 2011-07-28 |
20110183417 | POLYAMIDES FOR NUCLEIC ACID DELIVERY - The present invention provides a new class of non-viral transduction vectors that can be used for both in vivo and in vitro applications. In particular, these vectors can be used for gene transfer applications. These new gene transduction vectors can achieve transfer efficiencies far greater to commercially available polymeric and liposomal gene transfer vectors while maintaining little or no toxicity in vitro. Their low in vitro toxicity makes them ideal candidates for in vivo use. The present invention also provides a gene transfer vector that has comparable efficiency to a viral vector without the potential for a life-threatening immune response. Furthermore, the unique polycationic structure of these polymers associates with many suitable biologically active molecule, including oligonucleotides and polypeptides and other compounds that poses multiple cationic sites. The polymer can act as a delivery vehicle for the associated biologically active molecule, in vivo or in vitro, to the cells of interest for the biologically active molecule. Complexes according to the invention or portions thereof, can comprise a cellular delivery molecule or agent that can facilitate the translocation of the complex or portion thereof into cells. In some embodiments, cellular delivery molecules for use in the present invention may comprise one or more one or more polymers of the present invention, e.g., polyamides, dendritic macromolecules (polymers comprising an oligoamine shell and a cyclodextrin core), and carbohydrate-containing degradable polyesters. | 2011-07-28 |
20110183418 | Peptide-Polymer Cell Culture Articles and Methods of Making - Functionalized peptide monomers, peptides that have been functionalized to contain a polymerization moiety, are disclosed. The use of these functionalized peptide monomers to form peptide polymers which are useful as synthetic surfaces capable of supporting culture of cells in culture, particularly cells that will be used therapeutically, is also disclosed. Methods of making the surfaces and methods of using the surfaces are also disclosed. | 2011-07-28 |
20110183419 | SILICA SOL MATERIAL FOR PRODUCING BILOGICALLY DEGRADABLE AND/OR RESORBABLE SILICA GEL MATERIALS, THE PRODUCTION AND USE THEREOF - The invention concerns a novel silica sol material and its use for producing bioabsorbable and biodegradable silica gel materials having improved properties. The materials such as for example fibres, fibrous nonwoven webs, powders, monoliths and/or coatings are used, for example, in medical technology and/or human medicine, in particular for wound treatment. | 2011-07-28 |
20110183420 | MASS TAG REAGENTS FOR SIMULTANEOUS QUANTITATION AND IDENTIFICATION OF SMALL MOLECULES - A molecule identification and quantitation method is provided wherein a mass tag is conjugated to an analyte and the signature ion of the mass tag remains attached to the analyte after tandem mass spectrometry fragmentation (MS-MS or MS | 2011-07-28 |
20110183421 | COMPOSITION AND METHOD FOR CONVERTING A NON-PATHOGENIC PRION PROTEIN INTO A PATHOGENIC CONFORMATION AND USES THEREOF - Described herein is a composition for converting a non-pathogenic prion protein (“PrP | 2011-07-28 |
20110183422 | MEASUREMENT OF CURING - A method for increasing productivity and quality in production of cured polymer by a real time measurement of the progress of curing, in a mould cavity, which being filled with a compound to be cured, wherein a signal is generated by a wave at an ultrasonic or equivalent frequency, which is transmitted through the mould cavity, the time for the wave to pass through the compound in the mould and back is detected, and the detected signal being analyzed in a suitable data processing computer , to establish a graph showing a relationship between the time for the wave to pass through the compound in the mould and back, and the time of the curing of the compound. The graph is used to determine a feature of the compound by identifying at least one specific parameter of the graph, and using said parameter to control the production. | 2011-07-28 |
20110183423 | PROCESS FOR CONTROLLING IONIC LIQUID CATALYST ACTIVITY BY TITRATION - A process for determining ionic liquid catalyst deactivation including (a) collecting at least one sample of an ionic liquid catalyst; (b) hydrolyzing the at least one sample to provide at least one hydrolyzed sample; (c) titrating the at least one hydrolyzed sample with a basic reagent to determine a volume of the basic reagent necessary to neutralize a Lewis acid species of the ionic liquid catalyst; and (d) calculating the acid content of the at least one sample from the volume of basic reagent determined in step (c) is described. Processes incorporating such a process for determining ionic liquid catalyst deactivation are also described. These processes are an alkylation process, a process for controlling ionic liquid catalyst activity in a reaction producing by-product conjunct polymers, and a continuous process for maintaining the acid content of an ionic liquid catalyst at a target acid content in a reaction producing by-product conjunct polymers. | 2011-07-28 |
20110183424 | SCREENING FOR NEUROTOXIC AMINO ACID ASSOCIATED WITH NEUROLOGICAL DISORDERS - Methods for screening for neurological disorders are disclosed. Specifically, methods are disclosed for screening for neurological disorders in a subject by analyzing a tissue sample obtained from the subject for the presence of elevated levels of neurotoxic amino acids or neurotoxic derivatives thereof associated with neurological disorders. In particular, methods are disclosed for diagnosing a neurological disorder in a subject, or predicting the likelihood of developing a neurological disorder in a subject, by determining the levels of β-N-methylamino-L-alanine (BMAA) in a tissue sample obtained from the subject. Methods for screening for environmental factors associated with neurological disorders are disclosed. Methods for inhibiting, treating or preventing neurological disorders are disclosed. | 2011-07-28 |
20110183425 | Protein Complexes and Screening Methods - The application concerns an isolated protein complex comprising polypeptide components: (i) UTP20 HUMAN or a fragment, variant or homologue thereof; (ii) PWP2 HUMAN or a fragment, variant or homologue thereof; (iii) WDR46_HUMAN or a fragment, variant or homologue thereof; (iv) UTP18 HUMAN or a fragment, variant or homologue thereof; (v) MPPIO HUMAN or a fragment, variant or homologue thereof; (vi) WDR3_HUMAN or a fragment, variant or homologue thereof; (vii) TBL3 HUMAN or a fragment, variant or homologue thereof; (viii) WDR36_HUMAN or a fragment, variant or homologue thereof; and (ix) N0C4L HUMAN or a fragment, variant or homologue thereof. The application further concerns a method of identifying an agent that modulates the amount, function, activity, composition and/or formation of said protein complex; a method for the prevention or treatment of an eye disorder comprising administering to a subject in need thereof a suitable quantity of an agent that modulates the amount, function, activity, composition and/or formation of said protein complex; and a method of assessing whether a subject has or is likely to develop an eye disorder comprising determining whether the subject has an altered amount, function, activity, composition and/or formation of a protein complex. | 2011-07-28 |
20110183426 | Methods for Chemical Equivalence in Characterizing of Complex Molecules - The present invention provides for a method of characterizing and classifying a sample containing a complex molecule, such as a peptide or polypeptide mixture, protein, protein mixture, biologic and biosimilar by using physical analysis, such as mass spectrometry, and statistic methods. | 2011-07-28 |
20110183427 | METHOD FOR SEPARATING THE CONSTITUENTS OF A COMPLEX MIXTURE OF PROTEINS TO SUBMIT TO PROTEOMIC ANALYSIS AND APPARATUS THEREFOR - A method and an apparatus for separating the constituents of a complex mixture of proteins, for example an organic fluid, such as blood plasma, to submit to proteomic analysis. The method comprises, in particular, a step of distributing the complex mixture of proteins on a determined number n of separation elements different from each other ( | 2011-07-28 |
20110183428 | METHOD FOR ANALYZING C-TERMINAL AMINO ACID SEQUENCE OF PEPTIDE USING MASS SPECTROMETRY - The present invention provides a method for analyzing the C-terminal amino acid sequence of a peptide by using a reaction for successively releasing the C-terminal amino acids of the peptide, which method can suppress, when successively releasing the C-terminal amino acids of a peptide of long amino acid length, such a undesirable side reaction as cleavage of peptide bond in the intermediate position of the peptide and can carry out the chemical treatment thereof under widely applicable conditions; In the method, a dry sample of a peptide with long amino acid length is beforehand subjected to an N-acylation treatment; by using a reaction reagent where an alkanoic acid anhydride is combined with a small amount of a perfluoroalkanoic acid, successive release of C-terminal amino acids is conducted under mild conditions; a hydrolysis treatment is applied; then, selective fragmentization at site of arginine residue is performed by digestion by trypsin; thereafter, decreases in molecular weight are measured for the C-terminal side fragments derived from a series of reaction products with use of a MALDI-TOF-MS apparatus; thereby, the C-terminal amino acid sequence of the peptide sample is identified. | 2011-07-28 |
20110183429 | QUANTITATIVE ANALYSIS OF VITAMIN D3, VITAMIN D2, AND METABOLITES THEREOF - Quantification of vitamin D2, vitamin D3, and the monohydroxy and diihydroxy metabolites of vitamin D2 and vitamin D3, can comprise labeling analytes with mass spectrometry (MS) tagging reagents and performing LC-MSMS analysis of the labeled analytes. The labeled analytes can include a labeled standard and can have distinct retention times on a reversed phase column, as well as distinct masses. Under high energy collisions, reporter groups can be generated. The intensity or the peak area detected for each reporter group can be used for quantitation. In some embodiments, a one-step tagging reagent is used that is a dienophile-containing, labeled Diels Alder reagent. | 2011-07-28 |
20110183430 | GROUP SPECIFIC INTERNAL STANDARD TECHNOLOGY (GSIST) FOR SIMULTANEOUS IDENTIFICATION AND QUANTIFICATION OF SMALL MOLECULES - Reagents and methods are provided that permit simultaneous analysis of multiple diverse small molecule analytes present in a complex mixture. Samples are labeled with chemically identical but isotopically distinct forms of the labeling reagent, and analyzed using mass spectrometry. A single reagent simultaneously derivatizes multiple small molecule analytes having different reactive functional groups. | 2011-07-28 |
20110183431 | MASS ANALYSIS SYSTEM WITH LOW PRESSURE DIFFERENTIAL MOBILITY SPECTROMETER - A mass analysis system including a low pressure dissociation region and a differential mobility spectrometer. The differential mobility spectrometer including at least one pair of filter electrodes defining an ion flow path where the filter electrodes generate an electric field for passing through a selected portion of the sample ions based on the mobility characteristics of the sample ions. The differential mobility spectrometer also includes a voltage source that provides DC and RF voltages to at least one of the filter electrodes to generate the electric field, an ion inlet that receives sample ions that have passed through the low pressure dissociation region, and an ion outlet that outputs the selected portion of the sample ions. A mass spectrometer receives some or all of the selected portion of the sample ions. | 2011-07-28 |
20110183432 | TEST ELEMENT FOR ANALYZING AN ANALYTE PRESENT IN A SAMPLE OF A BODY FLUID, ANALYSIS SYSTEM AND METHOD FOR CONTROLLING THE MOVEMENT OF A FLUID CONTAINED IN A CHANNEL OF A TEST ELEMENT - Embodiments disclosed herein include an analysis system for the analysis of a body fluid sample for an analyte contained therein, comprising a test element and an evaluation device having a measuring station for measuring a measuring variable on the measuring zone of the test element. Also included is a mounting to hold a test element, the test element having an airflow channel with two expansion sections and a narrow section located between these expansion sections. The expansion sections may have a cross-sectional area that increases in comparison to the narrow section in the direction away therefrom. A connection channel is located between the narrow section and the analysis function channel such that an air exchange connection is formed. The airflow channel is located in such a manner that a partial vacuum, which is generated using an airflow flowing through the airflow channel, acts on the analysis function channel. | 2011-07-28 |
20110183433 | PIPETTE TIPS - Disclosed here are pipette tips useful for acquiring or dispelling liquids, and include one or more design that may increase fluid delivery precision and/or accuracy, and may reduce certain repetitive motions. | 2011-07-28 |
20110183434 | DIAGNOSTIC METHODS AND KITS USING FIBROBLAST GROWTH FACTOR-23 - The present invention describes the ability to identify chronic kidney disease (CKD) mortality risk in asymptomatic patients. For example, a patient having a normal glomerular filtration rate would be considered likely to have an increased mortality risk for chronic kidney disease upon the detection of an FGF-23 amino acid sequence that is above a normal level, but below CKD Stage 1 levels. Consequently, therapeutic strategies may be implements to prevent morbidity and mortality following chronic kidney disease progression. Such therapeutic strategies can involve phosphate reduction strategies (i.e., for example, reduced dietary intake of phosphorus and/or administration of phosphate binding compound). Further, kits are described providing instruction to determine a specific mortality risk based upon measured FGF-23 levels and estimated glomerular filtration rates. | 2011-07-28 |
20110183435 | Biodegradable Photoluminescent Polymers - The present invention describes a novel elastomeric biodegradable photoluminescent polymer (BPLP). The BPLPs of the present invention possess great processability and tunable fluorescence emission characteristics and are cell-compatible and biodegradable. The BPLPs of the present invention can serve as both implant materials and bioimaging probes. | 2011-07-28 |
20110183436 | DIAGNOSTIC METHODS FOR CONGESTIVE HEART FAILURE - The invention provides an assay for the quantification of circulating glycophorin in biological fluid samples. The circulating glycophorin measured by this assay is a truncated glycophorin diagnostic for congestive heart failure (CHF). | 2011-07-28 |
20110183437 | METHODS OF IDENTIFYING COMBINATIONS OF ANTIBODIES WITH AN IMPROVED ANTI-TUMOR ACTIVITY AND COMPOSITIONS AND METHODS USING THE ANTIBODIES - A method of identifying a combination of antibodies with a combined improved anti tumor activity is provided. The method comprising identifying at least two anti RTK antibodies capable of inducing synergistic endocytosis of the RTK in a cell expressing the RTK, thereby identifying the combination of antibodies with the combined improved anti-tumor activity. | 2011-07-28 |
20110183438 | Method for Sensing a Substance to be Detected in a Sample - A single-electron transistor comprising at least a substrate, a source electrode and a drain electrode formed on top of the substrate opposing to each other, and a channel arranged between the source electrode is disclosed wherein the channel is composed of ultra fine fibers. By having such a constitution, a sensor can have excellent sensitivity. | 2011-07-28 |
20110183439 | STRUCTURES INCORPORATING CONFORMATIONALLY FLEXIBLE CONJUGATED POLYMERS AND METHODS OF USE - Methods, compositions and articles of manufacture involving conformationally flexible conjugated polymers are provided. A structure is provided comprising the conformationally flexible conjugated polymer bound to or associated with at least one member of a binding pair comprising a sensor molecule and a target molecule or the complex they form. The conformationally flexible conjugated polymer comprises at least one angled linker having bonds to its two adjacent polymeric units which form an angle of less than about 155° with respect to one another. Methods of use of such structures and solutions comprising them are also provided. | 2011-07-28 |
20110183440 | SEMICONDUCTOR DEVICE AND MANUFACTURING METHOD THEREOF, AND THIN FILM DEVICE - A manufacturing method of a semiconductor device is disclosed. The manufacturing method includes the steps of forming a contact plug in an insulation film so as to be connected to an element on a semiconductor substrate, applying PLA pretreatment to the insulation film in an NH | 2011-07-28 |
20110183441 | METHOD OF FABRICATING SEMICONDUCTOR DEVICE - A semiconductor device and a method of fabricating a semiconductor device that includes forming an interlayer insulating film on a semiconductor substrate; depositing a first soft magnetic thin film on the interlayer insulating film through sputtering using a target containing at least one of Fe, Co, Ni, or alloys thereof, the target further containing at least one of Ti, Hf, or B, the sputtering being performed using an N | 2011-07-28 |
20110183442 | ENCAPSULANT LAYER FOR PHOTOVOLTAIC MODULE, PHOTOVOLTAIC MODULE AND METHOD FOR MANUFACTURING REGENERATED PHOTOVOLTAIC CELL AND REGENERATED TRANSPARENT FRONT FACE SUBSTRATE - An encapsulant layer for a photovoltaic module enabling recovering and recycling or reusing of reutilizeable resources such as a transparent front face substrate and photovoltaic cell and the like among constituents of a photovoltaic module, and a method for manufacturing a regenerated photovoltaic cell and a regenerated transparent front face substrate. The photovoltaic module is formed by laminating: a transparent front face substrate; a photovoltaic cell carrying a wiring electrode and a takeoff electrode, and an encapsulant layer is placed on at least one surface; and a rear face protecting sheet. The encapsulant layer is a separable layer formed mainly of a thermoplastic resin, and an output maintenance factor of photoelectronic power of the photovoltaic module using the encapsulant layer is in a range of 80% to 100%. | 2011-07-28 |
20110183443 | CONTACT PATTERNING METHOD WITH TRANSITION ETCH FEEDBACK - A method for forming a contact hole in a semiconductor device and related computer-readable storage medium are provided, the method and program steps of the medium including measuring a percentage of oxygen in an etching chamber, and controlling the percentage of oxygen in the etching chamber to enlarge a temporary inner diameter near a top of the contact hole. | 2011-07-28 |
20110183444 | METHOD FOR ELECTRON BEAM INDUCED ETCHING - The invention relates to a method for electron beam induced etching of a material ( | 2011-07-28 |
20110183445 | METHOD FOR MANUFACTURING SOI SUBSTRATE - An insulating layer is formed over a surface of a semiconductor wafer to be the bond substrate and irradiation with accelerated ions is performed, so that an embrittlement region is formed inside the wafer. Next, this semiconductor wafer and a base substrate such as a glass substrate or a semiconductor wafer are attached to each other. Then, the semiconductor wafer is divided at the embrittlement region by heat treatment, whereby an SOI substrate is manufactured in which a semiconductor layer is provided over the base substrate with the insulating layer interposed therebetween. Before this SOI substrate is manufactured, heat treatment is performed on the semiconductor wafer at 1100° C. or higher under a non-oxidizing atmosphere such as an argon gas atmosphere or a mixed atmosphere of an oxygen gas and a nitrogen gas. | 2011-07-28 |