30th week of 2015 patent applcation highlights part 9 |
Patent application number | Title | Published |
20150202344 | CELL CONSTRUCT FOR CELL TRANSPLANTATION AND CELL AGGREGATE FOR CELL TRANSPLANTATION - An object of the present invention is to provide a cell construct for cell transplantation capable of having a thickness suitable for cell transplantation, preventing the necrosis of transplanted cells, and forming blood vessels in the transplantation site after transplantation. The present invention provides a cell construct for cell transplantation which comprises polymer blocks having biocompatibility and cells of at least one type, wherein the plural polymer blocks are arranged in spaces between the plural cells. | 2015-07-23 |
20150202345 | Demineralized Bone Matrix - A demineralized bone matrix is produced by a process in which a bone body is placed in a first processing solution comprising an acid to demineralize the bone body. The bone body is periodically removed from the first solution at specific time intervals to perform at least one test, such as a compression test, on a mechanical property of the bone body. When the test yields a desired result, the bone body is exposed to a second processing solution that is less acidic than the first, thus minimizing the exposure of the bone body to the harsh acidic conditions of the demineralization phase of the process. | 2015-07-23 |
20150202346 | DEMINERALIZED BONE MATRIX - A demineralized bone matrix is produced by a process in which a bone body is placed in a first processing solution comprising an acid to demineralize the bone body. The bone body is periodically removed from the first solution at specific time intervals to perform at least one test, such as a compression test, on a mechanical property of the bone body. When the test yields a desired result, the bone body is exposed to a second processing solution that is less acidic than the first, thus minimizing the exposure of the bone body to the harsh acidic conditions of the demineralization phase of the process. | 2015-07-23 |
20150202347 | Compositions for Regenerating Defective or Absent Myocardium - Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function. | 2015-07-23 |
20150202348 | OMENTUM BASED SCAFFOLD AND DELIVERY SYSTEM - Compositions of matter comprising decellularized omentum are disclosed. The compositions may be scaffolds, hydrogels or hydrogel precursor compositions. Methods of generating the compositions are disclosed as well as uses thereof. | 2015-07-23 |
20150202349 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF BONE VOIDS AND OPEN FRACTURES - The present invention relates to compositions, methods and medical devices for the treatment of bone voids and bone defects. The methods of the invention comprise the step of applying to a bone void or bone defect site a composition comprising a matrix which provides local prolonged release of at least one antibiotic agent at the bone void site. | 2015-07-23 |
20150202350 | MATRIX SCAFFOLD WITH ANTIMICROBIAL ACTIVITY - The invention provides a scaffold of extracellular matrix polymers with recombinant chimeric peptides tethered thereto. The invention also provides recombinant chimeric peptides of antimicrobial peptides and extracellular matrix binding domains. The invention also provides methods for treating chronic wounds using the scaffold and/or recombinant chimeric peptides. | 2015-07-23 |
20150202351 | DYNAMIC SILK COATINGS FOR IMPLANTABLE DEVICES - Provided herein relates to implantable devices and systems with dynamic silk coatings. In some embodiments, the dynamic silk coatings can be formed in situ or in vivo. | 2015-07-23 |
20150202352 | FLEXIBLE TUBE, ENDOSCOPIC MEDICAL APPARATUS, AND RESIN COMPOSITION FOR TOP COAT LAYER - The present invention provides a flexible tube used for an endoscope and the like; an endoscopic medical apparatus that uses the flexible tube; and a resin composition for top coat layer used for the flexible tube. The flexible tube includes a flexible tube substrate that has a cylindrical shape and flexibility; a resin layer that covers the flexible tube substrate; and a top coat layer that covers the resin layer, in which the top coat layer contains a polymer compound derived from monomers including the following A to C. | 2015-07-23 |
20150202353 | Flexible Exudate Collection Canister - An orientation independent, disposable, flexible exudate management canister that is capable of conforming to curved surfaces, for collecting exudate fluids from a wound as part of a negative pressure wound therapy system. The canister may be used with existing Negative Pressure Wound Therapy (NPWT) suction pumps and wound dressings, or with the suction pump and wound dressing described in this embodiment to make a complete NPWT system. | 2015-07-23 |
20150202354 | Wound Dressing - The wound dressing combines an integrated mechanical aspirator for drawing exudate and fluids from the wound site and an internal absorbent pad for collecting exudate and fluids within the wound dressing. The collection pad has multi-layers including a layer of hyper-absorbent material, which acts as the fluid collection medium. The aspirator is a type of simple bulb syringe, which is integrated into top of the wound dressing in fluid communication with the collection pad. The aspirator has a hollow bulb head and a one-way purge vent. The vent allows air to be purged from the bulb head when manually compressed. Once compressed, the structural and material resilience of the bulb head causes its walls to expand back to their original shape thereby creating a vacuum (negative) pressure within the bulb head that assists in drawing exudate and fluids from the wound site into the collection pad. | 2015-07-23 |
20150202355 | WOUND CLOSURE AND DRAINAGE SYSTEM - A vacuum system for draining an open wound from liquids exuded therefrom,
| 2015-07-23 |
20150202356 | Passive Separation of Whole Blood - Described are systems, methods, and kits for compression sedimentation and whole blood separation. For example, a compression sedimentation system may include a compression stage configured to accept a flexible reservoir configured to contain a liquid mixture. The compression stage may include a base substrate and a compression substrate configured to apply a force to the flexible reservoir effective to create a pressure in the liquid mixture. An apparatus for whole blood separation may include a sedimentation system that separates whole blood into a supernatant including platelet rich plasma and a subnatant including red blood cells. At least one platelet-concentrating device may be included to receive the supernatant including the PRP and to separate a platelet concentrate and a platelet poor plasma from the supernatant. | 2015-07-23 |
20150202357 | Array of Hollow Fibers and a System and Method of Manufacturing Same - An array of hollow fibers including a plurality of hollow fibers of a predetermined diameter configured to receive a gas having oxygen therein and transfer the oxygen to a fluid and/or transfer carbon dioxide in the fluid to a gas. The array is configured in a predetermined pattern having a predetermined packing density that is a fraction of a total cross-sectional area of the array occupied by the hollow fibers. | 2015-07-23 |
20150202358 | EXTRACORPOREAL CIRCULATION DEVICE AND CONTROL METHOD - An extracorporeal circulation device having high safety without increases in the circuit scale and the power consumption includes a main control unit responsible for control of a motor drive circuit so as to yield a blood flow rate per unit time set by a user. The motor drive circuit applies a drive signal corresponding to the set blood flow rate to a motor. A sub-control unit configured by a field programmable gate array (FPGA) detects the drive signal applied to the motor and monitors whether or not the drive signal falls within an allowable range corresponding to the set blood flow rate. If the drive signal outside the allowable range is applied, the main control unit is deemed to be in an abnormal state and the main control unit is completely stopped. Then, the sub-control unit takes over the subsequent processing. | 2015-07-23 |
20150202359 | APPARATUS FOR MAKING EXTRACORPOREAL BLOOD CIRCULATION AVAILABLE - The present invention relates to an apparatus for making extracorporeal blood circulation available, in particular a heart-lung machine, comprising a venous connection and an arterial connection, between which a blood reservoir, a blood pump and a bubble detector for the detection of aft bubbles are provided, with, downstream of the bubble detector, an arterial line leading to the arterial connection via an arterial clamp and a bypass leading via a bypass clamp back into the blood reservoir which is connected to a pump extracting air from the blood reservoir. In addition, the present invention relates to a method of operating such an apparatus. | 2015-07-23 |
20150202360 | ARTERIAL CANNULA WHICH ALLOWS PERFUSION ALONG OPPOSING DIRECTIONS WITHIN A CANNULATED VESSEL - A cannula includes at least one opening at a distal tip, and further includes multiple fenestrations that are maintainable in position substantially immediately or slightly beyond a site or point of cannula entry into a vessel. The fenestrations, in combination with the opening(s) at the cannula's distal tip, enable the simultaneous perfusion of blood into the cannulated vessel along multiple directions, including opposing or anti-parallel blood flow directions relative to a central axis of the cannulated vessel. During a medical procedure (e.g., an extra-corporeal membrane oxygenation (ECMO) procedure) blood introduced into a vessel such as the femoral artery by way of the cannula can thus exit the cannula in a manner that provides concurrent blood flow in a first direction towards the heart and a second direction away from the heart. | 2015-07-23 |
20150202361 | DEVICES AND METHODS FOR MODULATING MEDIUM DELIVERY - A method includes establishing an initial resistive force on a contrast fluid in a contrast delivery modulation component and injecting the contrast fluid into the patient with an injection syringe fluidly connected to the injection catheter and the contrast fluid inlet port of the contrast delivery modulation component. A contrast delivery measurement component is used to assess a total volume of the contrast fluid injected into the patient and a resistive force imparted upon the contrast fluid in the chamber. | 2015-07-23 |
20150202362 | SYRINGE PUMP WITH PIVOTABLE DISPLAY - A medical pump comprises a pumping mechanism located in a housing and a display placed on a support member which is articulated on the housing. The support member is pivotable with respect to the housing around a first axis between a folded-back position and an folded-out position. The display is pivotable with respect to the support member around a second axis between a first position, called a non pivoted position, and a second position, called a pivoted position, wherein the first axis and the second axis are parallel to each other. This allows the support member, in a first movement, to pivot around the first axis and, in a second movement, to pivot the display around the second axis. These two movements are independent from each other and it is therefore possible to perform the movements simultaneously or subsequently. | 2015-07-23 |
20150202363 | APPARATUS AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS TO MUCOUS OR SEROUS MEMBRANE - A method, apparatus, and system are provided for mucous membrane therapy. The method includes receiving at least one body signal from a patient; detecting a condition of the patient based on the body signal; and administering the therapy to at least one of a mucous membrane or a serous membrane of the patient. A medical device system configured to implement the method is provided. A computer-readable storage device for storing instructions that, when executed by a processor, perform the method is also provided. | 2015-07-23 |
20150202364 | KIT, USE THEREOF AND METHOD FOR FILLING CONNECTIVE TISSUE OF THE SKIN - The invention concerns a kit and a syringe for use in a therapeutic method for intracutaneous filling of the collagen structure in connective tissue of the skin, and the use thereof, particularly as part of the treatment of skin defects, particularly skin diseases and signs of skin aging. | 2015-07-23 |
20150202365 | Spring Driven Injection Device - The present invention relates to an injection device for automatic torsion spring driven injection of a liquid drug. The injection device is of the type wherein a telescopically movable needle shield activates the release of the torque of the torsion spring to drive the injection when the needle shield is moved from its extended position to a retracted position. The injection device further has a needle holder carrying the injection needle, which needle holder is axially movable both in relation to the housing and in relation to the needle shield. It is therefore possible to retract the needle shield in relation to the housing and at the same time move the needle holder to its extended position such that the injection needle is presented outside the needle shield thereby providing for easy exchange of the injection needle. | 2015-07-23 |
20150202366 | AUTOINJECTOR - Described is an autoinjector comprising a case having a hole, a carrier adapted to hold a syringe and slidably disposed in the case, a cover telescopically coupled to the case and translatable relative to the case between a first position and a second position in which the cover covers the hole, and a releasable locking mechanism adapted to lock the cover in the second position. | 2015-07-23 |
20150202367 | ELECTRONIC AUTO-INJECTION DEVICE - An electronic automatic injection device including a housing configured to receive an injection module containing a material to be injected, an electric motor having a rotary drive output, at least one forward driving spring and a multifunctional electric motor driven drive assembly responsive to the rotary drive output of the electric motor and being operative in a first mode of operation, when the injection module includes a prefilled syringe, to enable the at least one forward driving spring to displace the prefilled syringe in a forward direction and in a second mode of operation, when the injection module includes a needleless cartridge, to eject the injectable liquid from the prefilled syringe through a needle. | 2015-07-23 |
20150202368 | Automatic Injection Device - The present invention relates to an automatic injection device ( | 2015-07-23 |
20150202369 | Spring-Loaded Injection Device with an Injection Button - The present invention relates to a spring-loaded medical injection device for automatically ejecting set doses of a drug having an injection button ( | 2015-07-23 |
20150202370 | MEDICAL DEVICE PROTECTION ASSEMBLY IN THE FORM OF AN ATTACHABLE WEIGHT ACTING AS IMPACT-ABSORBING STRUCTURE - The present invention relates to a medical device protection assembly and to a respective medical device. The protection assembly comprises at least one reorientation member being connectable with a medical device and being operable to orient the medical device into a predefined orientation in the event the medical device is subject to a free-fall. | 2015-07-23 |
20150202371 | CODED CARTRIDGE ASSEMBLY - Disclosed herein are cartridge assemblies that include coding features that help dedicate a medicament reservoir to specific injection devices. An exemplary cartridge assembly comprises a cylindrical inner surface for holding medicament and a cylindrical outer surface comprising at its proximal end one or more stops configured as coding elements protruding from the cylindrical outer surface. Each coding element is configured only to engage a corresponding coding feature on a dose setting and delivery mechanism, thereby allowing only the correct cartridge assembly to connect to the dose setting and delivery mechanism. | 2015-07-23 |
20150202372 | SYRINGE FOR THE APPLICATION OF MULTIPLE TOPICAL TREATMENTS - A syringe comprising: an applicator with a tip; a chamber that is in fluid communication with the application tip; a reservoir containing housing at least one ampule of medication; said reservoir separated by a port; a press that is configured be received by the reservoir and push the ampules of medication into the chamber through the port; and a plunger for pushing the ampules' contents of medication through the application tip. In one mode of operation: ampules of medication (each ampule can contain a different medication) are deposited into the reservoir of the syringe; the press is inserted into the reservoir and manipulated to push the ampules through the port into the chamber; and, the plunger is depressed to force the medications through the application tip. Preferably the syringe is used for dispensing topical medication, but it can be adapted for other medical and non-medical uses. | 2015-07-23 |
20150202373 | FORCE ACTUATED INJECTION DEVICE - An injection device including a barrel having an internal medication reservoir, a plunger received within the barrel and axially movable relative thereto, a grip fixed to the plunger and axially overlapping a portion of the barrel, the grip configured to be locked relative to the barrel to prevent axial movement therebetween, a needle attached to one end of the barrel, and a needle guard configured to retract into the barrel in response to force against an injection site to unlock the grip from the barrel to permit relative axial movement therebetween. | 2015-07-23 |
20150202374 | AUTO-INJECTOR - Provided is a cassette unit suitable for use with an auto-injector having an electrically powered drive unit. The cassette unit comprises a cassette unit housing defining a housing cavity, a rearward entrance to the cavity and a forward needle projection aperture. The housing cavity may receive a syringe. Axially movable within the barrel of the syringe for forward movement into contact with the syringe plunger, there is a plunger slaving part defining a circumferential wall arranged for frictional sliding relationship with the inner wall of the barrel, a rear drive-receiving face and a front plunger-contacting face. In capping relationship with the rearward entrance of the cassette unit housing there is an end-cap defining a drive rod-receiving opening for receipt of a drive rod for providing forward axial drive to the plunger slaving part. In a pre-use configuration, the plunger slaving part is shaped for releasable engagement with the end-cap. | 2015-07-23 |
20150202375 | PEN-TYPE DRUG INJECTION DEVICE AND ELECTRONIC ADD-ON MONITORING MODULE FOR|MONITORING AND LOGGING DOSE SETTING AND ADMINISTRATION - A supplemental device for attachment to an injection device, the supplemental device is presented having a processor arrangement; and a quantity determiner for determining a quantity of medicament that has been delivered, wherein the quantity determiner has a sensor arranged to detect movement of a drive screw of the injection device during medicament delivery. | 2015-07-23 |
20150202376 | Pen-Type Drug Injection Device and Electronic Add-On Monitoring Module for Monitoring and Logging dose Setting and Administration - A supplemental device for attachment to an injection device. A supplemental device for attachment to an injection device, the supplemental device comprising: a housing; an electromechanical switch arrangement, the electromechanical switch arrangement comprising: a main body; and a switching member, the switching member having a protrusion arranged to protrude from the main body so as to contact a surface of the injection device while the supplemental device is attached to the injection device; and a biasing member configured to bias at least a part of the main body of the electromechanical switch arrangement against the injection device while the supplemental device is attached to the injection device. | 2015-07-23 |
20150202377 | Supplemental Device for Attachment to an Injection Device - A supplemental device for attachment to an injection device, the supplemental device comprising: a housing; an electromechanical switch arrangement having an open state and a closed state, the electromechanical switch arrangement comprising a protrusion configured to contact a surface of the injection device while the supplemental device is attached to the injection device; a dose dialed detector operable to detect a dose of medicament dialed into the attached injection device; and a processor arrangement configured to: monitor the detected dose of medicament dialed into the attached injection device; detect a change in the state of the electromechanical switch arrangement; and change a display output of the supplemental device when a change in the state of the electromechanical switch arrangement is detected while a zero dose is dialed into the attached injection device. | 2015-07-23 |
20150202378 | Needle Shield with Specific Roughness - The present invention relates to a shield ( | 2015-07-23 |
20150202379 | INJECTOR - An injector including a syringe arranged along a longitudinal axis, a removable cover for removable engagement with the syringe and a cover removal assembly including an outer portion which is engagable by a user and is movable axially in a cover disengagement direction along an axial travel path with respect to the longitudinal axis and an inner portion which includes at least one engagement portion which is engagable with the removable cover, whereby axial movement of the inner portion in the cover disengagement direction removes the removable cover from the syringe, at least one of the outer portion and the inner portion being configured such as to provide an axially floating lost motion engagement between the outer portion and the inner portion. | 2015-07-23 |
20150202380 | Drug Delivery Device - The invention relates to a drug delivery device for setting and dispensing a dose of a drug, comprising: a support body having a first end defining a first opening and a second end defining a second opening, the support body configured to retain a syringe barrel sealed by a stopper slidably disposed therein along an axial direction and adapted to have an integrated needle or to be coupled with a needle assembly, a needle shield adapted to be coupled to one of the ends of the support body, slidably disposed thereon and keyed to the support body for preventing relative rotation, wherein at least one guiding track is defined on the support body and at least one retaining clip arranged on the needle shield is deflectable by the guiding track, wherein the guiding track is configured such that the retaining clip follows a first path when the needle shield is depressed from an extended position to a retracted position for needle extension and that the retaining clip follows a different second path when the needle shield is subsequently extended, wherein a non-return catch is arranged for catching the retaining clip at the end of the second path. | 2015-07-23 |
20150202381 | INJECTION NEEDLE INSERTION BARRIER - A catheter system includes a positioning catheter for receiving an injection needle into its lumen. Structurally, the injection needle incorporates a plurality of loops that are mounted directly onto its shaft. As the injection needle is moved in a distal direction to exit from the lumen of the catheter, the loops are individually biased to transition from a folded configuration, and into a deployed configuration. In their deployed configurations, the loops create a barrier that is oriented perpendicular to the needle. Thus, the barrier acts to limit the depth of insertion of the needle into target tissue of a patient, to a predetermined depth, and to prevent perforation of the target tissue by the catheter tip. | 2015-07-23 |
20150202382 | OPTICAL SENSOR FOR DETECTING INFUSION PUMP CASSETTE - An infusion pump has an optical detection system for determining whether or not a cassette of an administration tubing set is properly loaded in the pump. Operation of the pump may be enabled or disabled based on a determination of the cassette detection system. The optical cassette detection system includes a light emitter directing a light beam along an optical axis to a corresponding light detector aligned on the optical axis. The cassette detection system also includes a tab carried by the cassette and arranged such that when the cassette is properly loaded in the pump, the tab intersects the optical axis and blocks at least a portion of the light beam from reaching the detector. The detector signal is evaluated by signal evaluation electronics to determine if the detector signal level is below a predetermined threshold, indicating presence of the cassette. | 2015-07-23 |
20150202383 | OFF-AXIS OPTICAL SENSOR FOR DETECTING INFUSION PUMP CASSETTE - An infusion pump has an optical detection system for determining whether or not a cassette of an administration tubing set is properly loaded in the pump. Operation of the pump may be enabled or disabled based on a determination of the optical detection system. The optical cassette detection system includes a light emitter and a corresponding light detector on non-coincident emission and detection axes, and at least one optical element carried by the cassette. When the cassette is properly loaded in the pump, light from the emitter is redirected by the optical element from the emission axis to the detection axis for receipt by the detector, which registers an increased signal level. The detector signal is evaluated by signal evaluation electronics to determine if the detector signal level is above a predetermined threshold, indicating presence of the cassette. | 2015-07-23 |
20150202384 | ABSORPTION-BASED OPTICAL SENSOR FOR DETECTING INFUSION PUMP CASSETTE - An infusion pump has an optical cassette detection system for determining whether or not a cassette of an administration tubing set is properly loaded in the pump. Operation of the pump may be enabled or disabled based on a determination of the cassette detection system. The cassette detection system includes a light emitter and a corresponding photosensitive detector aligned along an optical axis, and window carried by the cassette. When the cassette is properly loaded in the pump, a light beam from the emitter enters the window, where a portion of the beam is absorbed and another portion of the beam is transmitted for receipt by the detector. The detector signal is evaluated by signal evaluation electronics to determine if the cassette is loaded. The determination may be based on an expected attenuation of the light beam corresponding to a predetermined light absorptance property of the window. | 2015-07-23 |
20150202385 | FLUORESCENCE-BASED OPTICAL SENSOR FOR DETECTING INFUSION PUMP CASSETTE - An infusion pump has an optical cassette detection system for determining whether or not a cassette of an administration tubing set is properly loaded in the pump. Operation of the pump may be enabled or disabled based on a determination of the cassette detection system. The cassette detection system includes a light emitter and a corresponding photosensitive detector, and a window carried by the cassette that includes a fluorophore. When the cassette is properly loaded in the pump, an excitation light beam from the emitter enters the window and excites the fluorophore, causing emission light in a wavelength band distinct from that of the excitation beam to be transmitted out of the window for receipt by the detector. The detector signal is evaluated by signal evaluation electronics to determine if the signal level is above a predetermined threshold, indicating the cassette is loaded. | 2015-07-23 |
20150202386 | VOLUME MONITORING DEVICE UTILIZING HALL SENSOR-BASED SYSTEMS - An apparatus has a plunger which is slidably received within a syringe housing between a first and second position. A hall sensor module is disposed on the apparatus. The hall sensor module includes a hall sensor and a magnet slidably disposed relative to the hall sensor. | 2015-07-23 |
20150202387 | Method and Nebulization Module Providing Constant Electric Power by Automatic Compensation - The invention provides an ultrasonic nebulizer comprising a circuit unit, a nebulization module, and a frequency sweeping unit. The invention utilizes the technique of maintaining constant electric power in the nebulization module of the ultrasonic nebulizer by automatic compensation of electric power consumption and/or current consumption. Using such a technique, the invention allows a fixed current consumption and electric power consumption of a nebulization module of an ultrasonic nebulizer by auto compensation, thereby improving nebulization performance. | 2015-07-23 |
20150202388 | APPARTUS AND METHOD FOR DISPERSING LIQUID IN AEROSOL - A system and method delivers an atomized solution to the interior volume of a building or room utilizing a venturi effect for the atomization. | 2015-07-23 |
20150202389 | FILTER INTERFACE FOR MULTIMODAL SURGICAL GAS DELIVERY SYSTEM - A surgical gas delivery system is disclosed that includes a device housing supporting a control unit and a filter interface having a seat for receiving a filter cartridge, the filter cartridge having a filter housing defining an interior reservoir, wherein sensors are coupled to the control unit for sensing a level of liquid within the reservoir of the filter cartridge to prevent contamination of the device, and wherein a set of blocking valves are provided in the device housing for interacting with the filter cartridge when it is received in the filter interface to control flow through suction and pressure lines of the device, and wherein the control unit is adapted to recognize a characteristic of the filter cartridge received in the filter interface. | 2015-07-23 |
20150202390 | FILTER INTERFACE FOR MULTIMODAL SURGICAL GAS DELIVERY SYSTEM - A surgical gas delivery system is disclosed that includes a device housing supporting a control unit and a filter interface having a seat for receiving a filter cartridge, the filter cartridge having a filter housing defining an interior reservoir, wherein sensors are coupled to the control unit for sensing a level of liquid within the reservoir of the filter cartridge to prevent contamination of the device, and wherein a set of blocking valves are provided in the device housing for interacting with the filter cartridge when it is received in the filter interface to control flow through suction and pressure lines of the device, and wherein the control unit is adapted to recognize a characteristic of the filter cartridge received in the filter interface. | 2015-07-23 |
20150202391 | FILTER INTERFACE FOR MULTIMODAL SURGICAL GAS DELIVERY SYSTEM - A surgical gas delivery system is disclosed that includes a device housing supporting a control unit and a filter interface having a seat for receiving a filter cartridge, the filter cartridge having a filter housing defining an interior reservoir, wherein sensors are coupled to the control unit for sensing a level of liquid within the reservoir of the filter cartridge to prevent contamination of the device, and wherein a set of blocking valves are provided in the device housing for interacting with the filter cartridge when it is received in the filter interface to control flow through suction and pressure lines of the device, and wherein the control unit is adapted to recognize a characteristic of the filter cartridge received in the filter interface. | 2015-07-23 |
20150202392 | METERING ELEMENT FOR AN INHALATION DEVICE AND INHALATION DEVICE COMPRISING A METERING ELEMENT - A metering element for an inhalation device is provided, comprising at least one opening being configured to receive a substance, wherein the opening comprises a width and an entire height, wherein the height extends along a longitudinal axis of the metering element and the width extends across the longitudinal axis, and wherein the continuous width of the opening is less than the entire height of the opening. Furthermore, an assembly for an inhalation device is provided, comprising a metering element and a sealing member wherein a removal of substance from the metering chamber upon mechanical cooperation of the metering element with the sealing member is prevented. | 2015-07-23 |
20150202393 | CPR VOLUME EXCHANGER VALVE SYSTEM WITH SAFETY FEATURE AND METHODS - A method for regulating gas flows into and out of a patient includes repetitively forcing respiratory gases out of the lungs. Respiratory gases are prevented from entering back into the lungs during a time between when respiratory gases are forced out of the lungs. Periodically, an oxygen-containing gas is supplied to the lungs. | 2015-07-23 |
20150202394 | VENTILATOR-INITIATED PROMPT OR SETTING REGARDING DETECTION OF ASYNCHRONY DURING VENTILATION - This disclosure describes systems and methods for monitoring and evaluating ventilatory parameters, analyzing those parameters and providing useful notifications and recommendations to clinicians. That is, modern ventilators monitor, evaluate, and graphically represent multiple ventilatory parameters. However, many clinicians may not easily recognize data patterns and correlations indicative of certain patient conditions, changes in patient condition, and/or effectiveness of ventilatory treatment. Further, clinicians may not readily determine appropriate ventilatory adjustments that may address certain patient conditions and/or the effectiveness of ventilatory treatment. Specifically, clinicians may not readily detect or recognize the presence of asynchrony during ventilation. According to embodiments, a ventilator may be configured to monitor and evaluate diverse ventilatory parameters to detect asynchrony and may issue notifications and recommendations suitable for a patient to the clinician when asynchrony is implicated. The suitable notifications and recommendations may further be provided in a hierarchical format. | 2015-07-23 |
20150202395 | BREATHING ASSISTANCE SYSTEM WITH SPEECH DETECTION - Disclosed is a breathing assistance system ( | 2015-07-23 |
20150202396 | ENDOTRACHEAL TUBE APPARATUS - This document provides endotracheal tube designs with features that can improve the efficacy, patient safety, and efficiency of endobronchial access. For example, this document provides endotracheal tube designs with features for atraumatic passage of the tube's distal tip through the vocal folds. In addition, this document provides endotracheal tubes that have variations in strength and flexibility properties along the length of the tube in an advantageous pattern to enhance the efficacy of the endotracheal tube. | 2015-07-23 |
20150202397 | PATIENT INTERFACE ASSEMBLY WITH FORCE LIMITER - The present invention relates to a patient interface assembly ( | 2015-07-23 |
20150202398 | BYPASS SYSTEM AND METHOD FOR RESPIRATORY THERAPY AND ANESTHESIA - The present invention provides a bypass system for respiratory therapy and anesthesia comprising a first bypass conduit for receiving a gas flow and for receiving a filtration device. The bypass system also has an activation means for redirecting the gas flow within the first bypass conduit. A second bypass conduit for receiving the gas flow from the first bypass conduit and the filtration device is also present in the system. The bypass system also has a passive control valve within the second bypass conduit to redirect air flow within the second bypass conduit and a conduit interconnected to the first and second bypass conduit for providing a passage of gases between the first and second bypass conduit when activated by the activation means wherein the activation means is activated when the first bypass conduit is not connected to a filtration device. | 2015-07-23 |
20150202399 | PLATFORM FOR OXYGEN GENERATION AND DELIVERY - A platform for oxygen generation and delivery is disclosed. The platform includes a hydrophobic substrate with at least one hydrophilic region permeable to gas flow formed thereon having an oxygen generating compound embedded in the at least one hydrophilic region. The platform further includes a microfluidic network with an inlet and an outlet bonded to the hydrophobic substrate with at least one fluid exchange region fluidly coupled to the inlet and the outlet and substantially matching the least one hydrophilic region. The microfluidic network is configured to receive an oxygen rich fluid at the inlet, communicate the oxygen rich fluid to the at least one fluid exchange region to mix with the oxygen generating compound, causing a chemical reaction resulting in formation of oxygen and a chemical byproduct, and communicate the chemical byproduct to the outlet, where the oxygen is permeated out of the at least one hydrophilic region. | 2015-07-23 |
20150202400 | Accelerated closed-circuit wash-in of tracer gas using bolus injection in lung function testing - The application relates to methods aiming at fast equilibration in the lungs of inhaled tracer gases by inhalation of a bolus of gas mixture followed by rebreathing in a closed system. Possible applications of the methods include inert gas rebreathing for fast wash-in of tracer gas for multiple-breath washout measurements to determine the lung clearance index (LCI) or other indices of ventilation inhomogeneity of the lungs or for pulmonary blood flow and lung volume determination by rebreathing. Furthermore the present application relates to a corresponding system. | 2015-07-23 |
20150202401 | CONVERSION OF NITROGEN DIOXIDE (NO2) TO NITRIC OXIDE (NO) - A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal. | 2015-07-23 |
20150202402 | HUMIDIFICATION CHAMBER FOR A RESPIRATORY ASSISTANCE APPARATUS - A respiratory assistance apparatus includes a flow generator and a humidifier. The humidifier includes a humidification chamber. The humidification chamber comprises a water tub that is configured to receive a volume of water. A lid is hingedly coupled to the water tub for enclosing a volume contained within the water tub. | 2015-07-23 |
20150202403 | VACUUM AND POSITIVE PRESSURE VENTILATION SYSTEMS AND METHODS FOR INTRATHORACIC PRESSURE REGULATION - Medical techniques include systems and methods for administering a positive pressure ventilation, a positive end expiratory pressure, and a vacuum to a person. Approaches also include treating a person with an intrathoracic pressure regulator so as to modulate or upregulate the autonomic system of the person, and treating a person with a combination of an intrathoracic pressure regulation treatment and an intra-aortic balloon pump treatment. | 2015-07-23 |
20150202404 | VALVE ARRANGEMENT AND A REBREATHING SYSTEM COMPRISING SAID VALVE ARRANGEMENT - This invention relates to a valve arrangement ( | 2015-07-23 |
20150202406 | MICROINJECTION CATHETER - An insertion device for delivering media inside a patient includes an outer guide tube having a side port. An inner guide tube is nested within the outer guide tube and movable axially within the outer guide tube. The inner guide tube includes a deflector at an end within the outer guide tube. The device also includes a catheter nested within the inner guide tube and movable axially within the inner guide tube. The deflector of the inner guide tube is positionable such that it deflects the dispensing end of the catheter outward through the opening in the outer guide tube when the catheter is advanced axially within the inner guide tube. A therapeutic delivery cannula may be nested within the catheter, such that the deflected end of the catheter determines the direction of travel of the therapeutic delivery cannula into patient tissue when the cannula emerges from the catheter. | 2015-07-23 |
20150202408 | Medical Device And Delivery Method Onto Offset Surface Of Mammal Tissue - A novel medical device and method for delivery of a scaffold for treatment of secondary lymphedema and ischemia is provided. In some embodiments a catheter medical device and magnetic guidance method are provided for delivering cell-seeded implants for guided lymphatic regeneration. | 2015-07-23 |
20150202409 | MEDICAL INSTRUMENT, AND MEDICAL-INSTRUMENT PRODUCTION METHOD - The present invention relates to a medical instrument capable of enhancing the slidability of an operating wire in a lumen. The medical instrument (for example, a catheter ( | 2015-07-23 |
20150202410 | APPARATUSES FOR STEERING CATHETERS - A steerable catheter device, comprising: a deflector configured with at least one groove, where the groove is a missing section disposed across a part of a cross-section of the deflector; and, a pull wire configured to effectuate bending of the deflector at the groove, being connected on the deflector distally of the groove. | 2015-07-23 |
20150202411 | Adjustable Vaginal Anchor for Uterine Tamponade Device and Methods of Using The Same - A device for use with a uterine tamponade apparatus, such as the Bakri postpartum hemorrhage balloon, is disclosed. The device comprises an adjustable anchor for deployment within the vagina to securely retain the balloon in its proper position within the uterine cavity, allowing the balloon to function as intended for the control and management of postpartum hemorrhage and uterine bleeding. Methods of use of the vaginal anchor are also disclosed. | 2015-07-23 |
20150202412 | MEDICAL SAFETY NEEDLE PREVENTIVE OF NEEDLEPOINT RE-EXPOSURE - A medical safety needle includes a needle body having a needlepoint, a covering body having a detent portion slidable on the needle body to catch the needlepoint so as to cover the needlepoint, and a resilient cantilever supporting the detent portion, a collar portion slidably fitting on the covering body, which is configured to get in contact with the cantilever to press the cantilever radially inwardly, and a housing being formed in a unitary body with the collar portion or having an end face on which the collar portion is capable of being seated, the housing being configured to carry the covering body from a first position to have the needlepoint exposed to a second position to have the needlepoint covered by the covering body. | 2015-07-23 |
20150202413 | DUAL TIP GUIDE WIRE - Embodiments of a guide wire having a dual tip design and methods for using the guide wire. | 2015-07-23 |
20150202414 | GUIDE WIRE INSERTION APPARATUS USED IN CATHETERIZATION - Disclosed herein is a guide wire insertion device for a catheter procedure. The guide wire insertion device for a catheter procedure includes an injection unit ( | 2015-07-23 |
20150202415 | INSERTION DEVICE - An insertion device ( | 2015-07-23 |
20150202416 | APPARATUS AND METHODS FOR TREATING OBSTRUCTIONS WITHIN BODY LUMENS - An apparatus is provided that is operable in different modes to perform various functions for treating a body lumen. The apparatus includes a shaft including proximal and distal ends, a lumen extending there between, and a balloon on the distal end. The apparatus includes a valve on the distal end that selectively opens or closes an outlet communicating with the lumen. With the valve open, fluid introduced into the lumen exits the outlet into a body lumen. With the valve closed, fluid introduced into the lumen expands the balloon. The valve may be biased to be closed, e.g., by a spring element disposed within the balloon. Optionally, the apparatus also includes an actuator for expanding a helical member within the balloon interior, e.g., either before or after expanding the balloon, such that the helical member and balloon may adopt an expanded helical shape for removing material within a body lumen. | 2015-07-23 |
20150202417 | DEVICES AND METHODS FOR TRANSDERMAL DRUG DELIVERY - Provided are devices for therapeutic interaction with an Abreu brain thermal tunnel (ABTT) terminus. Such devices are configured to provide one or more drugs to an ABTT terminus, and may provide heat to or remove heat from the ABTT terminus while providing the one or more drugs. | 2015-07-23 |
20150202418 | MICRONEEDLE-BASED DEVICES AND METHODS FOR THE REMOVAL OF FLUID FROM A BODY - Microneedle-based devices and associated methods for removing fluid from a body are described. The devices incorporate microneedles capable of fluidly linking the body to a high capacity absorbent material capable of absorbing at least 5 times its own weight of said fluid. The microneedles may be conventional hollow microneedles in which the bores are filled with a microporous material, hydrophobic hollow microneedles provided with bores having a hydrophilic lining, hollow hydrogel microneedles or solid microporous microneedles. | 2015-07-23 |
20150202419 | DEVICES FOR TARGETED DELIVERY OF THERAPEUTIC IMPLANTS - A barrel adapter for a syringe having a barrel and plunger. The adapter comprises a barrel tip and a needle retraction mechanism having a needle subassembly with a needle and a lumen, actuator subassembly, and biasing member. The needle subassembly moves from an injection to a retracted position within the barrel tip. The actuator subassembly includes a retainer connected to the barrel tip, a stylet held in a stylet disc, and a prong passing into the retainer. The stylet slides within the needle lumen and is spaced from the needle tip in the injection position. The biasing member biases the NOM from the retainer. A locking arrangement compresses the biasing member when locked and releases the biasing member when actuated by depression of the plunger, which moves the prong against the retainer. The biasing member moves the needle and stylet from the injection position to the retracted position when released. | 2015-07-23 |
20150202420 | TATTOO MACHINE - A tattoo machine for oscillating a tattoo needle includes a main housing and a motor secured to the main housing. A needle bar member is movably secured to the main housing for linear oscillation relative thereto. A drive mechanism is operatively connected to an output shaft of the motor and to the needle bar member for translating rotary movement of the output shaft into linear oscillation of the needle bar member. | 2015-07-23 |
20150202421 | PORTED CATHETER ADAPTER HAVING COMBINED PORT AND BLOOD CONTROL VALVE WITH VENTING - A ported catheter adapter having a combined blood control valve and port valve, wherein the combined valve comprises one or more vents that permit the passage of air and prevent the passage of fluids. The one or more vents are located on the outer surface of the valve so as to avoid being overlapped with the pathway of the side port. As such, fluid communication between the side port and the vents is prevented. Various venting configurations are provided. The invention further includes a valve actuator that is advanced through a slit in the membrane of the valve to provide a pathway for fluid to bypass the valve. | 2015-07-23 |
20150202422 | PORTED CATHETER ADAPTER WITH INTEGRATED SEPTUM ACTUATOR RETENTION - A ported catheter adapter and septum actuator having various features to prevent displacement and dislodging of the septum actuator when accessing the patient's vasculature via the inserted infusion device. In particular, the systems and methods of the present invention provide an intravenous infusion device incorporating a septum actuator with a retention tab that interacts with a retention ring that is incorporated into the valve of a side port. This interaction retains the septum actuator within the lumen of the catheter adapter, thereby allowing for subsequent access to the patient's vasculature. | 2015-07-23 |
20150202423 | MEDICAL DEVICE HYBRID POLYMERIC STRUCTURES AND COATINGS WITH IMPROVED LUBRICITY AND DURABILITY - A method for making a tubular medical device having a hybrid polymeric structure includes forming a first layer comprising a non-woven fibrous matrix made of a first polymeric material and forming a second layer comprising a second polymeric material about the first layer such that at least a portion of the second polymeric material of the second layer embeds into at least a portion of the first polymeric material of the first layer. | 2015-07-23 |
20150202424 | INJECTION PORT WITH ARTICULATED STOPCOCK - The present invention is an injection port with an articulated stopcock allowing a syringe to be connected to an IV line and, depending upon the orientation of the stopcock, allow (1) bidirectional flow of fluid through the stopcock into the IV line, (2) no flow or (3) unidirectional flow of fluid through the stopcock and into or out of the IV line. The invention is particularly useful for using a syringe for aspirating an IV line and then injecting a medicine from the syringe into the IV line. Once a syringe is connected, the invention allows one-handed manipulation of the articulated stopcock into the three orientations by simply moving the connected syringe into one of the three orientations, thereby eliminating the need for using two hands—one to operate the syringe and the other to operate the handle. | 2015-07-23 |
20150202425 | STOPCOCK FLOW PATH SWITCHING DEVICE - This stopcock flow path switching device includes: a three-way stopcock having a flow path switching cock and provided to, by switching of the flow path switching cock, allow flow path switching between a state in which a contrast agent introducing flow path is formed by coupling a flow path on the patient side to a flow path on the injector head side and a state in which a blood pressure measuring flow path is formed by coupling the flow path on the patient side to a flow path on the blood pressure transducer side; and a clamp mechanism for closing the flow path of the three-way stopcock communicating with the injector head side, in the state in which the blood pressure measuring flow path is formed. | 2015-07-23 |
20150202426 | Fluid Delivery System, Fluid Path Set, and Pressure Isolation Mechanism with Hemodynamic Pressure Dampening Correction - The fluid delivery system includes a pressure isolation mechanism including a first lumen associated with the pressurizing device, a second lumen associated with the low pressure fluid delivery system, and a pressure isolation port, a first valve having a normally open position permitting fluid communication between the first lumen and the second lumen and movable to a closed position when fluid pressure in the first lumen reaches a predetermined pressure level, the first valve isolating the pressure isolation port from the first lumen in the closed position, and a second valve associated with the second lumen and regulating fluid flow through the second lumen, wherein the second valve substantially isolates the low pressure fluid delivery system from hemodynamic blood pressure signals. A method for correcting for dampened hemodynamic blood pressure signals in a fluid delivery system is also described. | 2015-07-23 |
20150202427 | DEVICE FOR AUGMENTING BLOOD FLOW, TISSUE PERFUSION AND FLUID DISTRIBUTION BY NEUROMUSCULAR STIMULATION IN HORSES AND OTHER NON-HUMAN MAMMALS - The invention relates to a method and device for neuromuscular stimulation of one or more muscles, or muscle groups, with one or more beneficial effects selected from increasing arterial, venous and capillary blood flow, increasing flux of interstitial fluid and lymphatic drainage, increasing tissue oxygenation, enhancing heat distribution, enhancing the distribution of pharmaceutical products, and enhancing performance and recovery from exertion in horses. | 2015-07-23 |
20150202428 | CUTANEOUS ELECTRODE - A windowed electrode assembly includes a foam layer having windows. Each window receives a corresponding gel pad that is sized such that it is contained by the window's sidewalls. The windowed electrode assembly includes a foam backing layer that forms a back wall for the windows such that each gel pad is encased by the window's sidewalls and back wall. | 2015-07-23 |
20150202429 | Device for Muscle Stimulation - A device for muscle stimulation of the trunk and/or leg musculature by electromyostimulation, comprising a one-part or multi-part suit ( | 2015-07-23 |
20150202430 | BRAIDED LEAD WITH IMBEDDED FIXATION STRUCTURES - In some examples, a method of making a therapy delivery element configured for at least partial insertion in a living body includes braiding a plurality of fibers to form an elongated braided structure with a lumen. At least one reinforcing structure is weaved into the fibers of the braided structure. A portion of the reinforcing structure is extended from the braided structure to form at least one fixation structure. At least one of the braided structure or the reinforcing structure can be attached to at least one of an electrode assembly or a connector assembly. | 2015-07-23 |
20150202431 | MULTI-PIECE DUAL-CHAMBER LEADLESS INTRA-CARDIAC MEDICAL DEVICE AND METHOD OF IMPLANTING SAME - A leadless intra-cardiac medical device (LIMD) includes an electrode assembly configured to be anchored within a first wall portion of a first chamber of a heart. The electrode assembly includes an electrode main body having a first securing helix, an electrode wire segment extending from the body, and a first segment-terminating contact positioned on the electrode wire segment. The device further includes a housing assembly configured to be anchored within a second wall portion of a second chamber of the heart. The housing assembly includes a body having a second securing helix, a housing wire segment extending from the body, and a second segment-terminating contact positioned on the housing wire segment. The device also includes a connector block that electrically connects the electrode wire segment to the housing wire segment by retaining the first and second segment-terminating contacts. | 2015-07-23 |
20150202432 | ELECTRODE STRUCTURE FOR DEEP BRAIN STIMULATION - An electrode structure is incorporated into an implantable lead for deep brain stimulation. The electrode structure comprises multiple radial electrode elements. The radial electrode elements of the electrode structure are separated by holes (e.g., slots) and held together by end rings of the electrode structure. The electrode elements are separated from one another at a later stage of a manufacturing process through the use of centerless grinding that removes the end rings. | 2015-07-23 |
20150202433 | METHOD AND APPARATUS FOR DIRECTED PROPAGATION OF NEURAL STIMULATION - A neural stimulation system delivers neural stimulation to a target nerve with control of direction of propagation of evoked neural signals in one or more fiber types of the target nerve using electrode configuration, thereby providing effective therapy while minimizing unintended effects. In various embodiments, mechanical parameters of a multi-polar electrode are determined to provide directed propagation of the neural stimulation by effecting neural conduction block in or near the stimulation site. In various embodiments, the electrode includes a cathode for evoking action potentials and a plurality of anodes for blocking the propagation of the evoked action potentials in specified direction(s) and fiber type(s) while minimizing the formation of virtual cathodes. | 2015-07-23 |
20150202434 | ENERGY PHYSIOTHERAPY CARE INSTRUMENT - Disclosed is an energy physiotherapy care instrument comprises a box-shaped body, a massage handle, a power-transmitting apparatus installed inside the massage handle, a control circuit board configured and fixed inside the box-shaped body to regulate the temperature of the power-transmitting apparatus, a power module to provide power to the control circuit board, a wire connecting between the power-transmitting apparatus and the control circuit board. The massage handle comprises a plastic casing and a massage head, for contacting the human body, mounted on the plastic casing and having a plurality of energy particles embedded inside. The instant disclosure provides power to the energy particles via a thermal conduction to introduce the energy particles into the deep layers of skin and then inside the human body. The instant disclosure has remarkable results, such as substantial healthcare, cell repair, and cell protection, as well as light and conveniently portable. | 2015-07-23 |
20150202435 | WIRELESS CARDIORESONANCE STIMULATION - An apparatus for the cardio-synchronised stimulation of skeletal or smooth muscle, but excluding the heart muscles, in a counterpulsation mode of a patient. The apparatus comprises an active and a passive electrode for attachment to said patient, a signal processor having a configuration input for varying a time delay associated with counterpulsation mode stimulation, and a sensing system for sensing information relating to the performance of the patient's heart and for transmission of information signals to said signal processor, said signal processor producing control signal information relating to stimulation signals to be applied to said active electrode in a counterpulsation mode, a stimulation signal generator associated with said active electrode for generating stimulation signals, wireless transmission means for transmitting said control signal information from said signal processor to said stimulation signal generator whereby said stimulation signal generator applies stimulation signals to said active electrode in accordance with said signal information. | 2015-07-23 |
20150202436 | CARDIAC RESYNCHRONIZATION THERAPY OPTIMIZATION BASED ON INTRACARDIAC IMPEDANCE - Methods and/or devices used in delivering cardiac resynchronization therapy based on a plurality of device parameters (e.g., A-V delay, V-V delay, etc.) are optimized by setting a device parameter based on selection data. The selection data may be acquired by acquiring temporal fiducial points (e.g., heart sounds) associated with at least a part of a systolic portion of at least one cardiac cycle and/or temporal fiducial points associated with at least a part of a diastolic portion of the at least one cardiac cycle for each of a plurality of electrode vector configurations, and extracting measurements from the intracardiac impedance signal acquired for each of a plurality of electrode vector configurations based on the temporal fiducial points. The acquired selection data may be scored and used to optimize the device parameter. | 2015-07-23 |
20150202437 | SYSTEMS AND METHODS FOR DELIVERING PULMONARY THERAPY - An example of a system may include an electrode and a pulse generation system. The electrode may be configured to be implanted near a neural target that innervates airways. The pulse generation system may be configured to be operably connected to the electrode to deliver depletion block stimulation through the electrode to alleviate symptoms of pulmonary disease. The pulse generation system and the electrode may be configured to cooperate to capture axons in the neural target. The depletion block stimulation may include a series of pulses at a depletion pulse frequency. | 2015-07-23 |
20150202438 | VARYING THE EFFECTIVE COIL AREA FOR AN INDUCTIVE TRANSCUTANEOUS POWER LINK - A prosthesis including an external device and an implantable component. The external device includes a first inductive communication component. The implantable component includes a second inductive communication component, wherein the implantable component is configured to be implanted under skin of a recipient. The external device is configured to transmit power via magnetic induction transcutaneoulsy to the implantable component via the second inductive communication component. The internal component is configured to receive at least a portion of the power transmitted from the external device via the inductive communication component. At least one of the first and second inductive communication components comprise an inductive communication component configured to vary its effective coil area. | 2015-07-23 |
20150202439 | Package for an Implantable Neural Stimulation Device - An implantable device, including a first electrically non-conductive substrate; a plurality of electrically conductive vias through the first electrically non-conductive substrate; a flip-chip multiplexer circuit attached to the electrically non-conductive substrate using conductive bumps and electrically connected to at least a subset of the plurality of electrically conductive vias; a flip-chip driver circuit attached to the flip-chip multiplexer circuit using conductive bumps; a second electrically non-conductive substrate attached to the flip-chip driver circuit using conductive bumps; discrete passives attached to the second electrically non-conductive substrate; and a cover bonded to the first electrically non-conductive substrate, the cover, the first electrically non-conductive substrate and the electrically conductive vias forming a hermetic package. | 2015-07-23 |
20150202440 | Chaotic desynchronization of neural populations with non-pulsatile inputs - A method is provided for finding an energy-optimal stimulus which gives a positive Lyapunov exponent, and hence desynchonization, for a neural population. The method is illustrated for three different neural models. Not only does it achieve desynchronization for each model, but it also does so using less energy than recently proposed methods, suggesting a powerful alternative to pulsatile stimuli for deep brain stimulation. Furthermore, we calculate error bounds on the optimal stimulus which will guarantee a minimum Lyapunov exponent. Also, a related control strategy is developed for desynchronizing neurons based on the population's phase distribution. | 2015-07-23 |
20150202441 | DEPLETION BLOCK TO BLOCK NERVE COMMUNICATION - An example of a system may include a depletion block neural stimulator and a depletion block controller. The depletion block neural stimulator may be configured to deliver a depletion block stimulation to a nerve. The depletion block stimulation may include a series of pulses at a pulse frequency within a range between about 100 Hz to about 1000 Hz. The depletion block controller may be configured to communicate with the depletion block neural stimulator and control the depletion block stimulation. The depletion block controller may be configured to receive a start depletion block signal and respond to the received start depletion block signal by initiating the delivery of the depletion block stimulation to the nerve, and the depletion block controller may be configured to receive a stop depletion block signal and respond to the received stop depletion block signal by terminating the delivery of the depletion block stimulation to the nerve. | 2015-07-23 |
20150202442 | Antenna Providing Variable Communication With an Implant - A device may include a primary antenna configured to be located external to a subject and at least one processor in electrical communication with the primary antenna. The at least one processor may be configured to cause transmission of a primary signal from the primary antenna to an implantable device, wherein the implantable device includes at least one pair of modulation electrodes. The at least one processor may be further configured to adjust one or more characteristics of the primary signal to generate a sub-modulation control signal adapted so as not to cause a neuromuscular modulation inducing current at the at least one pair of modulation electrodes when received by the implantable device and to generate a modulation control signal adapted so as to cause a neuromuscular modulation inducing current at the at least one pair of modulation electrodes when received by the implantable device. | 2015-07-23 |
20150202443 | CARDIAC RESYNCHRONIZATION THERAPY OPTIMIZATION BASED ON INTRACARDIAC IMPEDANCE AND HEART SOUNDS - Methods and/or devices used in delivering cardiac resynchronization therapy based on a plurality of device parameters (e.g., A-V delay, V-V delay, etc.) are optimized by setting a device parameter based on selection data. The selection data may be acquired by acquiring temporal fiducial points (e.g., heart sounds) associated with at least a part of a systolic portion of at least one cardiac cycle and/or temporal fiducial points associated with at least a part of a diastolic portion of the at least one cardiac cycle for each of a plurality of electrode vector configurations, and extracting measurements from the intracardiac impedance signal acquired for each of a plurality of electrode vector configurations based on the temporal fiducial points. The acquired selection data may be scored and used to optimize the device parameter. | 2015-07-23 |
20150202444 | SYSTEMS AND METHODS FOR SELECTIVE STIMULATION OF NERVE FIBERS IN CAROTID SINUS - An example of a system may include at least one electrode for placement on tissue in a carotid sinus region and a stimulator. The stimulator may be configured to use the at least one electrode to deliver neural stimulation to a baroreceptor region or at least one nerve innervating the baroreceptor region in the carotid sinus region to elicit a baroreflex response, and to deliver a blocking stimulation to a carotid body or at least one nerve innervating the carotid body in the carotid sinus region to inhibit a chemoreceptor response, the stimulator configured to simultaneously deliver the neural stimulation and the blocking stimulation. | 2015-07-23 |
20150202445 | ACTIVE IMPLANTABLE MEDICAL DEVICE FOR VAGAL STIMULATION WITH OPTIMIZATION OF VENTRICULAR FILLING - An active implantable medical device for vagal stimulation with optimization of ventricular filling is disclosed. The device delivers stimulation pulses to the vagal nerve of the patient with an adjustable energy level. The device includes a hemodynamic sensor for measuring hemodynamic parameters of the patient's cardiac cycles and delivering a timing parameter representative of the ventricular filling time. The energy level of the vagal stimulation pulses is adjusted dynamically and repeatedly over several cardiac cycles. The energy level is varied during successive cardiac correlative changes in the filling time (FT | 2015-07-23 |