29th week of 2010 patent applcation highlights part 39 |
Patent application number | Title | Published |
20100184163 | METHOD FOR PRODUCTION OF L-GLUTAMINE - A polypeptide comprising an amino acid sequence in which one or more amino acids are deleted, substituted or added in the amino acid sequence of a glutamine synthetase 2 derived from a microorganism belonging to a coryneform bacterium, wherein the coryneform bacterium producing the polypeptide has L-glutamine productivity, a DNA encoding the polypeptide, a recombinant DNA comprising the DNA, a microorganism comprising the DNA or the recombinant DNA, and a process for producing L-glutamine using the microorganism are provided. | 2010-07-22 |
20100184164 | Microorganism Producing L-Methionine Precursor And Method Of Producing L-Methionine And Organic Acid From The L-Methionine Precursor - The present invention relates to a method for producing L-methionine and organic acid comprising the following steps: Step 1) preparing a strain producing L-methionine precursor and producing L-methionine precursor by the fermentation of the strain; Step 2) producing L-methionine and organic acid by the enzyme reaction process with the L-methionine precursor as a substrate, and microorganism strains used in each step. | 2010-07-22 |
20100184165 | NOVEL ALDOLASE, AND METHOD FOR PRODUCING OPTICALLY ACTIVE IHOG AND MONATIN - The present invention relates to a method for producing optically active IHOG, which can in turn be used for the production of monatin. The present invention further relates to a method for producing optically active monatin, and aldolase used for these methods. As such, the present invention enables the synthesis of 4-(Indole-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid with high optical purity, which is useful as an intermediate in the synthesis of optically active monatin, from indole pyruvic acid and pyruvic acid (or oxaloacetic acid). | 2010-07-22 |
20100184166 | METHOD FOR PRODUCING ALKALOIDS - The present invention provides a method for producing an alkaloid, for example, reticuline, comprising providing dopamine as a substrate for a series of actions of monoamine oxidase, norcoclaurine-6-O-methyltransferase, coclaurine-N-methyltransferase and 3′-hydroxy-N-methylcoclaurine-4′-O-methyltransferase. | 2010-07-22 |
20100184167 | METHOD FOR PRODUCING PURIFIED TEA EXTRACT - A purified tea extract is improved in taste by reducing a percentage of gallates in the non-polymer catechins. A process according to the present invention for the production of a purified tea extract includes subjecting a tea extract to a hydrolysis treatment, causing the tea extract to adsorb on the activated carbon, and then bringing a basic aqueous solution or an aqueous solution of an organic solvent into contact with the activated carbon to elute the non-polymer catechins. | 2010-07-22 |
20100184168 | PROCESS FOR PRODUCING FATTY ACIDS - A process for producing fatty acid by hydrolyzing oil and fat, which comprises: a first step of partially hydrolyzing oil and fat by either of the following method (a) or (b), and a second step of hydrolysis by the other method: (a) enzymatic hydrolysis using an immobilized enzyme which is an enzyme immobilized on a support and (b) high pressure and temperature hydrolysis. A method of efficiently producing fatty acid with a reduced content of trans-unsaturated fatty acid in the constituent fatty acids and having a good appearance with reduced coloring by hydrolysis of oil and fat is provided. | 2010-07-22 |
20100184169 | Modified Photosynthetic Microorganisms With Reduced Glycogen and Their Use in Producing Carbon-Based Products - This disclosure describes genetically modified photosynthetic microorganisms, including Cyanobacteria, that contain one or more mutations or deletions in a glycogen biosynthesis or storage pathway, which accumulate a reduced amount of glycogen as compared to a wild type | 2010-07-22 |
20100184170 | Development of a Fermentative Enrichment Culture and Two Pure Isolates that Biotransform High Concentrations of Chloroform and Other Halomethanes - Disclosed are fermentative enrichment cultures and two pure isolates there from for use in biotransformation of halomethanes. Disclosed bioaugmentation cultures are dominated by Enterobacteriaceae, and are implemented together with one or more electron donors such as corn syrup, glucose, and the like, and a corrinoid catalyst such as vitamin B | 2010-07-22 |
20100184171 | Materials and Methods for Efficient Succinate and Malate Production - Genetically engineered microorganisms have been constructed to produce succinate and malate in mineral salt media in pH-controlled batch fermentations without the addition of plasmids or foreign genes. The subject invention also provides methods of producing succinate and malate comprising the culture of genetically modified microorganisms. | 2010-07-22 |
20100184172 | SYSTEM FOR THE PRODUCTION OF AROMATIC MOLECULES IN STREPTOMYCES - A process for the production of natural ferulic acid, coniferyl alcohol and/or vanillin, includes the bio-conversion of eugenol by a bacteria belonging to the | 2010-07-22 |
20100184173 | MICROORGANISMS FOR THE PRODUCTION OF METHYL ETHYL KETONE AND 2-BUTANOL - A non-naturally occurring microbial organism having a methyl ethyl ketone pathway includes at least one exogenous nucleic acid encoding a methyl ethyl ketone pathway enzyme expressed in a sufficient amount to produce methyl ethyl ketone. The methyl ethyl ketone pathway includes a β-ketothiolase, a β-ketovalerate decarboxylase and an enzyme selected from the group consisting of a β-ketovaleryl-CoA hydrolase and a β-ketovaleryl-CoA transferase. Alternatively, the methyl ethyl ketone pathway includes a 2-methylacetoacetyl-CoA thiolase, a 2-methylacetoacetate decarboxylase and an enzyme selected from the group consisting of a 2-methylacetoacetyl-CoA hydrolase and a 2-methylacetoacetyl-CoA transferase. Either pathway can further include a methyl ethyl ketone reductase to produce 2-BuOH. A method for producing methyl ethyl ketone or 2-BuOH includes culturing these non-naturally occurring microbial organisms under conditions, and for a sufficient period of time, to produce methyl ethyl ketone or 2-BuOH. | 2010-07-22 |
20100184174 | PROCESS FOR THE OXIDATIVE CLEAVAGE OF VINYLAROMATICS USING PEROXIDASES OR LACCASES - The invention relates to a method for the oxidative cleavage of vinyl aromatics of the formula (1) characterized in that (a) compound(s) of the formula (1) is/are oxidized to aldehydes and ketones of the formulas (2) and (3), respectively, in the presence of molecular oxygen using at least one enzyme selected from peroxidases and laccases as a catalyst, according to the following general reaction scheme: | 2010-07-22 |
20100184175 | BGL6 Beta-Glucosidase and Nucleic Acids Encoding the Same - The present invention provides a novel β-glucosidase nucleic acid sequence, designated bgl6, and the corresponding BGL6 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL6, recombinant BGL6 proteins and methods for producing the same. | 2010-07-22 |
20100184176 | BIOMASS HYDROTHERMAL DECOMPOSITION APPARATUS, METHOD THEREOF, AND ORGANIC MATERIAL PRODUCTION SYSTEM USING BIOMASS MATERIAL - A biomass hydrothermal decomposition apparatus includes, a biomass feeder ( | 2010-07-22 |
20100184177 | PLASTIC DISPOSABLE REACTOR SYSTEM - A plastic, disposable reactor (“PDR”) system is presented that will allow growth of microorganisms at various temperatures and pressures cost effectively. In this invention, the use of the system for aquaculture of algae is presented. The use of the reactor will allow carbon sequestration and significant production of a renewable energy source. The incorporation of recycled materials in various components of the plant also benefits the environment. | 2010-07-22 |
20100184178 | INCREASED ISOPRENE PRODUCTION USING MEVALONATE KINASE AND ISOPRENE SYNTHASE - The invention features methods for producing isoprene from cultured cells having increased expression levels and/or activity levels of a mevalonate kinase polypeptide and an isoprene synthase polypeptide. The invention also provides methods for producing isoprene from cultured cells having reduced accumulation of intermediates (such as mevalonate, isopentenyl diphosphate, 3,3-dimethylallyl diphosphate, geranyl diphosphate, or farnesyl diphosphate) in the biosynthesis of isoprene or isoprenoids that may otherwise cause undesirable amounts of growth inhibition, toxicity, or cell death. The resulting isoprene compositions may have increased yields and/or purity of isoprene. | 2010-07-22 |
20100184179 | MICROBIAL-MEDIATED METHOD FOR METAL OXIDE NANOPARTICLE FORMATION - The invention is directed to a method for producing metal oxide nanoparticles, the method comprising: (i) subjecting a combination of reaction components to conditions conducive to microbial-mediated formation of metal oxide nanoparticles, wherein said combination of reaction components comprise: metal-reducing microbes, a culture medium suitable for sustaining said metal-reducing microbes, an effective concentration of one or more surfactants, a reducible metal oxide component containing one or more reducible metal species, and one or more electron donors that provide donatable electrons to said metal-reducing microbes during consumption of the electron donor by said metal-reducing microbes; and (ii) isolating said metal oxide nanoparticles, which contain a reduced form of said reducible metal oxide component. The invention is also directed to metal oxide nanoparticle compositions produced by the inventive method. | 2010-07-22 |
20100184180 | SYSTEM, METHOD, AND DEVICE FOR THE EXPRESSION OR REPRESSION OF PROTEINS - This invention relates to systems, methods, and devices for inducing and/or repressing the expression of proteins. More particularly, the invention relates to systems, methods, and devices for inducing and/or repressing the expression of proteins in plastids. An exemplary embodiment involves the regulation of the expression of proteins involved in hydrogen production to stimulate the production of hydrogen gas using the methods, systems, and devices described herein. | 2010-07-22 |
20100184181 | Genetic Cluster of Strains of Streptococcus Thermophilus Having Appropriate Acidifying and Texturizing Properties for Dairy Fermentations - The invention relates to a genetic cluster of strains of | 2010-07-22 |
20100184182 | METHOD FOR PREPARING BIOLOGICAL TISSUE - This invention provides a means for preparing biological tissue within a short period of time. This invention provides a method for preparing biological tissue comprising: adding a culture solution containing cells and an extracellular matrix component that was separately prepared to a culture vessel having an inner bottom surface, which is a non-cell-adhesive surface; and performing cell culture while centrifugal or magnetic force toward the inner bottom surface is applied to cells to obtain biological tissue comprising multi-layered cells within a short period of time. | 2010-07-22 |
20100184183 | COLLAGEN SCAFFOLD MODIFIED BY COVALENT GRAFTING OF ADHESION MOLECULES, ASSOCIATED METHODS AND USE THEREOF FOR CARDIOVASCULAR AND THORACIC CELL THERAPY AND CONTRACTILE TISSUE ENGINEERING - Materials and methods for improving the biological properties and electromechanical performance of collagen scaffolds used for cell transplantation, including the fixation of biocompatible reagents and adhesion molecules which control cell adhesion, apoptosis, survival and/or differentiation simultaneously. The grafting of adhesion molecules to collagen matrices renders same suitable for use in vascular and cardiothoracic surgery/medicine, as well as in cell therapy for the heart and in artificial heart muscle engineering. Also, a simple method for grafting and optimising the presentation of adhesion peptides or biological agents when the scaffold is made from collagen and/or contains accessible thiol, amine or carboxyl groups. | 2010-07-22 |
20100184184 | Production of Conjugates - Disclosed is a method for indirectly coupling a small molecule ligand to a molecule to be labelled with the ligand, the method comprising the step of: contacting a scaffold molecule, to which is attached at least one small molecule ligand, with the molecule to be labelled, the scaffold molecule having at least one group which is reactive towards a receiver moiety present or formed in situ on the molecule to be labelled, so as to forma bond between the scaffold molecule and the molecule to be labelled, thereby indirectly coupling the small molecule ligand to the molecule to be labelled. | 2010-07-22 |
20100184185 | Isolated luciferases and the use thereof - The invention relates to the nucleotide and amino acid sequences, and to the activity and use, of the luciferases LuAL, Lu164, Lu16, Lu39, Lu45, Lu52 and Lu22. | 2010-07-22 |
20100184186 | NOVEL RIGIDOPORUS MICROPORUS LACCASE - An isolated | 2010-07-22 |
20100184187 | IN VITRO RECOMBINATION METHOD - The present invention relates, e.g., to in vitro method, using isolated protein reagents, for joining two double stranded (ds) DNA molecules of interest, wherein the distal region of the first DNA molecule and the proximal region of the second DNA molecule share a region of sequence identity, comprising contacting the two DNA molecules in a reaction mixture with (a) a non-processive 5′ exonuclease; (b) a single stranded DNA binding protein (SSB) which accelerates nucleic acid annealing; (c) a non strand-displacing DNA polymerase; and (d) a ligase, under conditions effective to join the two DNA molecules to form an intact double stranded DNA molecule, in which a single copy of the region of sequence identity is retained. The method allows the joining of a number of DNA fragments, in a predetermined order and orientation, without the use of restriction enzymes. | 2010-07-22 |
20100184188 | Alkaline Protease - It is an object of the present invention to provide alkaline proteases having industrially sufficient protein productivity and a significant detergency. In the alkaline proteases, the amino acid residues at (a) position 9, (b) position 49, (c) position 194, (d) position 212, (e) position 237, (f) position 245, (g) position 281, (h) position 313, (i) position 379 and (j) position 427 in SEQ ID NO: 2 are selected from the following amino acid residues; Position (a); glutamine, Position (b); glutamine, Position (c); lysine or arginine, Position (d); arginine, asparagine or glutamine, Position (e); asparagines, Position (f); asparagines. Position (g); arginine, Position (h); asparagines, Position (i); lysine, arginine, glutamic acid or aspartic acid, and Position (j); arginine. | 2010-07-22 |
20100184189 | PROTEIN FOR THE CHEMOENZYMATIC PRODUCTION OF L-THREO-HYDROXYASPARTATE - A simple mutant of the natural asparagine oxygenase comprises at least the amino acids 13 to 318 of the natural asparagine oxygenase AsnO. In this protein according to the present invention, comprising at least the amino acids 13-318 of AsnO D241N, the amino acid residue at position 241 of the natural asparagine oxygenase AsnO is exchanged from aspartate (D) to asparagine (N). The protein according to the present invention, comprising at least the amino acids 13-318 of AsnO D241N, is produced by means of a directed mutagenesis from the AsnO wild type, cloning of this expression plasmid into a vector, transformation of the vector plasmid construction into a host organism and expression of the recombinant protein. The protein according to the present invention is suitable for the chemoenzymatic and enantioselective production of L-threo-hydroxyaspartate from L-aspartate. The protein is substrate-specific and converts quantitatively L-aspartate into L-threo-hydroxyaspartate. | 2010-07-22 |
20100184190 | Influencing viral lipid constituents - This invention provides compositions, methods and systems to modulate the lipid content and membrane characteristics of cells and virions. Growth of host cells on media containing particular amounts, classes and/or combinations of lipid supplements can influence the lipid content of the cell and viruses grown on the cell. Lipids, such as cholesterol esters, sphingomyelin, glycolipids, containing C16:0, C18:0, C18: 1n9 and/or C18:2n6 fatty acids, can influence cell permissivity for virus infection, virus yield, virus immunogenicity and/or membrane phase transition temperatures. | 2010-07-22 |
20100184191 | NOVEL METHOD FOR GENERATION OF RNA VIRUS - The present invention provides a method for generating negative-strand, segmented RNA viruses using linear expression constructs in the presence of helper virus. | 2010-07-22 |
20100184192 | AVIAN INFLUENZA CHIMERIC VLPS - This invention discloses a method of increasing production of virus-like particles comprising expressing an avian influenza matrix protein. The invention also comprises methods of making and using said VLPs | 2010-07-22 |
20100184193 | OVEREXPRESSION OF AMINOACYL-tRNA SYNTHETASES FOR EFFICIENT PRODUCTION OF ENGINEERED PROTEINS CONTAINING AMINO ACID ANALOGUES - Methods for producing modified polypeptides containing amino acid analogues are disclosed. The invention further provides purified dihydrofolate reductase polypeptides, produced by the methods of the invention, in which the methionine residues have been replaced with homoallylglycine, homoproparglycine, norvaline, norleucine, cis-crotylglycine, trans-crotylglycine, 2-aminoheptanoic acid, 2-butynylglycine and allylglycine. | 2010-07-22 |
20100184194 | GOLDEN YELLOW ALGAE AND METHOD OF PRODUCING THE SAME - The present invention relates to a method for cultivating carotenoid rich golden yellow algae by varying the ratio of carbon to nitrogen content in the culture medium during cultivation and supplementing the media periodically with citrate and acetate compounds to enhance the carotenoid production and produce change in the colour of blue-green algae to golden yellow. | 2010-07-22 |
20100184195 | Recycling System for Manipulation of Intracellular NADH Availability - The present invention describes a novel recombinant NADH recycling system that is used as a process for producing reduced compounds. In a specific embodiment, the reduced compounds include ethanol, succinate, lactate, a vitamin, a pharmaceutical and a biodegraded organic molecule. The NADH recycling system effects metabolic flux of reductive pathways in aerobic and anaerobic environments. | 2010-07-22 |
20100184196 | COMPOSITE YEAST SUITABLE FOR HIGH CONCENTRATION ALCOHOL FERMENTATION FROM SUGAR-CONTAINING RAW MATERIALS - The present invention relates to a composite yeast suitable for high concentration alcohol fermentation from sugar-containing raw materials, characterizing in that the composite yeast comprises any kind of dried yeast selected from Brewers yeast | 2010-07-22 |
20100184197 | Methods For Harvesting Biological Materials Using Membrane Filters - The present disclosure relates to methods for harvesting biological materials, such as, for example, microalgal cells, using membrane filters, such as ceramic-based membrane filters. | 2010-07-22 |
20100184198 | Systems and Methods of Urea Processing to Reduce Sorbent Load - The present invention provides novel methods for removal and disposal of ammonia from spent dialysate in a dialysis system. Ammonium ions present in spent dialysate are converted into gaseous ammonia by raising the pH of the spent dialysate solution in a first reactor. Gaseous ammonia diffuses through a semi-permeable hydrophobic membrane at the outlet of the first reactor and into a second reactor via a gas channel. The second reactor converts gaseous ammonia into an ammonium compound for easy disposal. | 2010-07-22 |
20100184199 | Well Plate Reactor - A well plate and its supporting devices provide capabilities found in larger fermenters, such as controlling the oxygen level, the pH level, and temperature of the contents of the well. The well plate includes a plurality of wells, each of which can be independently controlled. Apertures in the wells, for example, provide access for a gas supply and sensors within each well provide data relating to, e.g., oxygen and/or pH level in the well. A control system controls the gas supply for each well based on the information provided by the sensor within the well. Similarly, temperature control elements, such as a heater or cooler, is placed in thermal contact with the interior of the well, as is a temperature measurement element. A control system can independently control the temperature of the contents of the well based on information provided by the temperature measurement element for that well. | 2010-07-22 |
20100184200 | Cell culture device - The present invention relates to a cell culture device which includes: a cell culture container comprising a container body and a neck connecting to the container body wherein the container contains a top wall, a bottom wall having a first opening, and at least one side wall to define a cell culture zone, and an end of the neck has a second opening for cells or culture media being injected into the cell culture zone; a biosensor chip having a detective surface which faces the top wall of the cell culture container; and a fastening component for the biosensor chip being fastened in the first opening of the bottom wall. The cell culture of the present invention can be used for real-time detection of the cell growth and further for drug screening. | 2010-07-22 |
20100184201 | MEASURING UNIT FOR MEASURING CHARACTERISTICS OF A SAMPLE LIQUID, IN PARTICULAR VISCOELASTIC CHARACTERISTICS OF A BLOOD SAMPLE - The present invention is directed to a measuring unit, for measuring characteristics of a sample liquid, comprising a support member, having at least one upper bearing arm, with an upper bearing unit, at least one lower bearing arm, with a lower bearing unit, and a base, for being attachable to a respective measuring system; a shaft, having shaft toes and being rotatably supported about a rotation axis, by said upper bearing unit, and said lower bearing unit, wherein said upper bearing unit, said lower bearing unit, and said shaft toes form toe bearings, respectively; an interface member, having a detecting element, and a drive element, said interface member, being fixed on said shaft, and being connected to a coupling shaft, with a probe connector section, for measuring characteristics of said sample liquid; wherein said interface member, and the coupling shaft, are coaxially aligned with said shaft. | 2010-07-22 |
20100184202 | Thermal Reaction Device and Method for Using the Same - An M×N matrix microfluidic device for performing a matrix of reactions, the device having a plurality of reaction cells in communication with one of either a sample inlet or a reagent inlet through a via formed within an elastomeric block of the device. Methods provided include a method for forming vias in parallel in an elastomeric layer of an elastomeric block of a microfluidic device, the method comprising using patterned photoresist masks and etching reagents to etch away regions or portions of an elastomeric layer of the elastomeric block. | 2010-07-22 |
20100184203 | STRAW EQUIPPED WITH A PLUG COMPRISING A FILTERING ELEMENT - This is a straw that comprises a tube ( | 2010-07-22 |
20100184204 | NOVEL GLYPHOSATE-N-ACETYLTRANSFERASE (GAT) GENES - Novel proteins are provided herein, including proteins capable of catalyzing the acetylation of glyphosate and other structurally related proteins. Also provided are novel polynucleotides capable of encoding these proteins, compositions that include one or more of these novel proteins and/or polynucleotides, recombinant cells and transgenic plants comprising these novel compounds, diversification methods involving the novel compounds, and methods of using the compounds. Some of the novel methods and compounds provided herein can be used to render an organism, such as a plant, resistant to glyphosate. | 2010-07-22 |
20100184205 | NUCLEIC ACIDS INVOLVED IN VIRAL INFECTION - Provided herein are isolated viral and human nucleic acids associated with viral infection and various nucleic acid molecules relating thereto or derived therefrom. The nucleic acids may be useful for the prevention, treatment and diagnosis of viral infections. | 2010-07-22 |
20100184206 | TARGETING PSEUDOTYPED RETROVIRAL VECTORS - The present invention relates to retroviral vectors, particularly lentiviral vectors, pseudotyped with Sindbis envelope and targeted to specific cell types via a targeting moiety linked to the envelope. | 2010-07-22 |
20100184207 | METHODS FOR PRODUCING INTERFERING RNA MOLECULES IN MAMMALIAN CELLS AND THERAPEUTIC USES FOR SUCH MOLECULES - Methods for producing interfering RNA molecules in mammalian cells are provided. Therapeutic uses for the expressed molecules, including inhibiting expression of HIV, are also provided. | 2010-07-22 |
20100184208 | hTERT GENE EXPRESSION REGULATORY GENE - Disclosed is a novel substance capable of regulating the expression of a telomerase reverse transcriptase gene in a cell of a mammal A gene capable of regulating the expression of hTERT, comprising a nucleotide sequence depicted in SEQ ID No: 1 or 2. The expression of a telomerase reverse transcriptase gene can be inhibited by inhibiting the expression of the gene. By utilizing this mechanism, the expression of a telomerase reverse transcriptase gene can be regulated. | 2010-07-22 |
20100184209 | COMPOSITIONS AND METHODS FOR INHIBITING GENE SILENCING BY RNA INTERFERENCE - The present invention provides compositions and methods for inhibiting gene silencing by the RNAi pathway. The RNAi inhibitors of the invention have a reverse complement (RC) region to the target molecule of interest (e.g., miRNA) in association with at least one flanking region coupled to either at the 3′ or 5′ end of the RC region. The flanking regions can be single-stranded or can have one or more regions of double stranded nucleic acid with or without a hairpin loop. The RNAi inhibitors described herein can inhibit endogenous targets, including but not limited to microRNAs, or piRNAs, or can be used to inhibit the effects of exogenously introduced molecules, such as synthetic siRNAs, siRNAs expressed from vector constructs (e.g., viral expression systems), or siRNAs generated by enzymatic methods. Inhibition is specific, potent, prolonged, and can be performed on a single target or multiple targets simultaneously. | 2010-07-22 |
20100184210 | METHOD FOR ISOLATING CELLS | 2010-07-22 |
20100184211 | Tumour-Associated Peptides that Bind to MHC Molecules - The invention relates to a tumor-associated peptide containing an amino sequence, which is selected from the group consisting of SEQ ID NO:1 to SEQ ID NO:79 of the enclosed listing. The peptide has the ability to bind to a molecule of the human major histocompatibility complex (MHC) class-I. The invention also relates to the use of the peptides for manufacture of a medicament and for treating tumorous diseases. The invention further relates to a pharmaceutical composition, which comprises at least one of the peptides. | 2010-07-22 |
20100184212 | HUMAN EMBRYONIC STEM CELL DERIVED MESODERM-LIKE EPITHELIUM TRANSITIONS TO MESENCHYMAL PROGENITOR CELLS - Human embryonic stem cells (hESC) have the potential to produce all of the cells in the body. They are also able to self-renew indefinitely, sparking the hope they could be used as a source for large scale production of therapeutic cell lines. The present invention relates to a monolayer differentiation culture system that induces hESC (WA09 and BG01) to form epithelial sheets with mesodermal gene expression patterns (BMP4, RUNX1, GAT A4). These E-cadherin+ CD90lovv cells then undergo apparent epithelial-mesenchymal transformation (EMT) for the derivation of mesenchymal progenitor cells (hES-MC) that by flow cytometry are negative for hematopoietic (CD34, CD45 and CD 133) and endothelial (CD31 and CD 146) markers, but positive for markers associated with mesenchymal stem cells (MSC) (CD73, CD90, CD105 and CD166). To determine their functionality, we tested their capacity to produce the three lineages commonly associated with MSC and found they could form osteogenic and chondrogenic, but not adipogenic lineages. The derived hES-MC were able to remodel and contract collagen I lattice constructs to an equivalent degree as keloid fibroblast control cells and were induced to express αSMA when exposed to TGF-β1, but not PDGF-B. This data suggests the derived hES-MC cells are multipotent cells with potential uses in tissue engineering/regenerative medicine and for providing a highly reproducible cell source for adult-like progenitor cells. | 2010-07-22 |
20100184213 | APOCRINE CELL LINE - An apocrine cell line is obtained by the steps of isolating an apocrine cell from primary tissue, culturing the isolated cell in a first culture medium, removing unattached cells from the first culture medium and transferring said unattached cells to a second culture medium comprising an effective concentration of a phorbol ester, and thereby establishing an apocrine cell line exhibiting long-term proliferation capability, which after many cultures is indicative of indefinite proliferation. | 2010-07-22 |
20100184214 | METHOD FOR PRODUCTION OF DENDRITIC CELL - The present invention provides methods for producing DCs, which comprise the step of culturing DC precursor cells in the presence of multiple cytokines, dendritic cells produced thereby, and uses thereof. The methods of the present invention enable production of large quantities of DC precursors with a high ability to differentiate into DCs. The present invention enables one to obtain large quantities of DCs from a small number of DC precursor cells, and therefore makes it easier to increase the number of DCs for administration in DC-based anti-tumor immunotherapy, treatment of infection, and such. Thus, an enhancement is expected for the effect of DC vaccines. | 2010-07-22 |
20100184215 | MODIFIED THIOREDOXIN - The present invention relates to a human modified thioredoxin composed of any of the following polypeptides: (a) a polypeptide modified by alteration or chemical modification of a cysteine residue at position 35 with another amino acid in an amino acid sequence of SEQ ID NO:2; and (b) a polypeptide having an amino acid sequence having one or more substituted, deleted, inserted or added amino acids in positions except for positions 32 and 35, preferably positions 32 to 35 in the amino acid sequence of SEQ ID NO:2, and having an apoptosis-inducing activity. | 2010-07-22 |
20100184216 | hTERT GENE EXPRESSION REGULATORY GENE - Disclosed is a novel substance capable of regulating the expression of a telomerase reverse transcriptase gene in a cell of a mammal. A gene capable of regulating the expression of hTERT, comprising a nucleotide sequence depicted in SEQ ID No: 1 or 2. The expression of a telomerase reverse transcriptase gene can be inhibited by inhibiting the expression of the gene. By utilizing this mechanism, the expression of a telomerase reverse transcriptase gene can be regulated. | 2010-07-22 |
20100184217 | STEM CELL LINES, THEIR APPLICATION AND CULTURE METHODS - New lines of stem cells from the growing antlers of deer (Cervidae) and the application of said cells in the reconstruction of connective tissue, preferentially bone, cartilage or adipose tissue, in humans and animals; as well as a method of culturing them and the application of tissues from growing deer antlers in the production of the MIC-1 stable stem cell line. | 2010-07-22 |
20100184218 | Isolation and Culture-Expansion Methods of Mesenchymal Stem/Progenitor Cells From Umbilical Cord Blood, And Differentiation Method of Umbilical Cord Blood-Derived Meschymal Stem/Progenitor Cells Into Various Mesenchymal Tissues - There is provided a method for the isolation and cultivation of mesenchymal stem/progenitor cells from umbilical cord blood, and also to a method for the differentiation of the umbilical cord blood-derived mesenchymal stem/progenitor cells into various mesenchymal tissues. The method include overlaying umbilical cord blood onto Ficoll-Hypaque solution; centrifuging the umbilical cord blood on the Ficoll-Hypaque solution to obtain a mononuclear cell layer; reacting cells obtained by monolayer culture of the mononuclear cells with antibodies to mesenchymal stem/progenitor cell-specific antigens for a predetermined period of incubation time; isolating only cells bound to their corresponding antibodies using a cell sorter; and cultivating the isolated cells, thereby obtaining mesenchymal stem/progenitor cells with high purity and excellent viability. | 2010-07-22 |
20100184219 | Methods and Apparatuses Relating to Cell Culture Media - A method of preparing cell culture media for use in culturing cells and an apparatus for carrying out the method. The method includes providing a vessel containing cell culture media and exposing the cell culture media to a first controlled atmosphere having a predetermined O | 2010-07-22 |
20100184220 | PREVASCULARIZED TISSUE TRANSPLANT CONSTRUCTS FOR THE RECONSTRUCTION OF A HUMAN OR ANIMAL ORGAN - The invention relates to a tissue transplant construct for the reconstruction of a human or animal organ. Here said tissue transplant construct is intended to comprise | 2010-07-22 |
20100184221 | METHOD FOR ISOLATION OF CELL, SERUM-FREE CULTURE MEDIUM FOR CELL, AND METHOD FOR CULTURE OF CELL - The present invention provides a method for isolating cells, in particular, stem cells, which method comprises the steps of: dissociating cells from a tissue of animal origin; seeding and incubating the cells in a culture vessel with no surface treatment; and selecting cells adhered to the vessel. | 2010-07-22 |
20100184222 | METHOD FOR PREPARING BIOLOGICAL TISSUE - This invention provides a method for preparing biological tissue in which the thickness (i.e., the number of cell layers) can be easily regulated, culture can be conducted within a shorter period of time than is possible with conventional techniques, and addition of unfavorable components is not necessary. The method of the invention comprises adding a cell-containing culture solution to a culture vessel having a non-cell-adhesive inner bottom surface, conducting cell culture while centrifugal force toward the inner bottom surface is applied to the cells in the vessel, forming tissue via intercellular adhesion, and detaching and collecting the resulting tissue from the inner bottom surface. | 2010-07-22 |
20100184223 | Biomaterial based on a hydrophilic polymeric carrier - The present invention relates to a biomaterial for cell or tissue culture, based on a polymeric carrier, which contains at least one crosslinkable hydrophilic polymer. The polymer is functionalized with groups that are selected from maleimide, vinylsulfonic, acrylate, alkyl halide, azirine, pyridyl, thionitrobenzene acid groups, or arylating groups. The invention relates further to a method of production of said biomaterial, and the use of particular functionalizing groups for the production of a biomaterial for the cultivation of tissue and/or cells. The biomaterial can have biofactors that exert a particular action on cells. | 2010-07-22 |
20100184224 | PLANT CELL WALL LOOSENING ACTIVITY OF GROUP 2/3 ALLERGENS OF GRASS POLLEN - The present invention provides nucleic acids and polypeptide sequences for a novel class of expansin-related proteins, designated group 2/3 allergen, which comprise the group 2 and group 3 allergens from grass, a purified group 3 allergen Lol p 3, and method of using the nucleic acids sequences and proteins of the invention. Group 2/3 allergens of the invention are significant wall-loosening agents. They are capable of altering cell wall properties, which may effect growth, flexibility, and mechanical strength in tissues in which they are expressed. | 2010-07-22 |
20100184225 | USE OF A CELLULAR EXTRACT FOR A MITOTIC REMODELING OF CHROMOSOMES - The present invention relates to the use of a female germinal cell (egg) extract of pluricellular organisms in M-phase of the cell cycle for a mitotic remodeling of chromosomes of donor cells of pluricellular organisms, wherein the mitotic remodeling confers to the nucleus of the donor cells the ability to adapt themselves to the early embryonic development, in particular to the replication phases, in order to carry out the embryonic development or to obtain stem cells. | 2010-07-22 |
20100184226 | MEDIA CONDITIONING FOR IMPROVING GENE DELIVERY EFFICIENCY TO DIFFERENTIATING EMBRYONIC STEM CELLS - The present invention provides systems and methods for improving the efficiency of a transient gene delivery system to differentiating embryonic stem (ES) cells by serum starving the targeted cells for one to three days prior to transfection. Such a serum starvation surprisingly resulted in increased expression of a constitutively-controlled plasmid from 50.4% to 83.2% of the population and increased expression of a promoter/enhancer controlled plasmid from ˜1.4% to ˜3.7% of the population. | 2010-07-22 |
20100184227 | PLURIPOTENT STEM CELLS OBTAINED BY NON-VIRAL REPROGRAMMING - Methods for reprogramming primate somatic cells to pluripotency using an episomal vector that does not encode an infectious virus are disclosed. Pluripotent cells produced in the methods are also disclosed. | 2010-07-22 |
20100184228 | DEVICE FOR ANALYSIS AND ANALYZING APPARATUS AND METHOD USING THE DEVICE - A device for analysis used for transferring a solution to a measurement spot | 2010-07-22 |
20100184229 | PORTABLE EXPLOSIVE OR DRUG DETECTION SYSTEM - A portable chemical analytical apparatus to analyze a test swipe includes a heater to warm the test swipe to a predetermined temperature; a clamp to secure the test swipe to the heater; one or more pumps to dispense one or more chemicals onto the test swipe from a disposable cartridge; a fan to remove chemical vapors rising a predetermined distance from the test swipe; and a camera to capture an image of the test swipe for automated analysis. | 2010-07-22 |
20100184230 | NANOCRYSTALS HAVING POLYNUCLEOTIDE STRANDS AND THEIR USE TO FORM DENDRIMERS IN A SIGNAL AMPLIFICATION SYSTEM - Provided are compositions and assay kits comprising functionalized nanocrystals having extending therefrom a plurality of polynucleotide strands of known sequence; wherein primary dots are used to operably link to a molecular probe, and secondary dots comprise a plurality of polynucleotide strands which are complementary to the plurality of polynucleotide strands of the primary dots. Also provided is a method for detecting the presence or absence of target molecule in a sample comprising operably linking primary dots to molecular probe, contacting the complex formed with the sample, contacting the sample with successive additions of secondary dots and primary dots. If target molecule is present in the sample, the primary dots and secondary dots will form dendrimers that can be detected by fluorescence emission. | 2010-07-22 |
20100184231 | Method for the determination of an analyte comprising a primary amino group, and kit for labeling said analyte - The invention provides a method for labeling an analyte comprising a primary amino group, the method comprising:
| 2010-07-22 |
20100184232 | METHOD AND APPARATUS FOR OLIGO PEPTIDE SYNTHESIS - An oligo peptide synthesis apparatus comprises a stationary apparatus part, which is stationary in relation to the frame and a movable apparatus part. The movable apparatus part comprises an oligo peptide synthesis reaction holder, which comprises a number of receptors for receiving a corresponding number of vessels and the receptors are located on a circle. The movable apparatus part comprises a revolveable holder, which has a disengageable coupling for connecting the revolveable holder to the oligo peptide synthesis reaction holder. | 2010-07-22 |
20100184233 | MATERIAL FOR PRESSURE MEASUREMENT - The invention provides a material for pressure measurement which utilizes a color forming reaction between a colorless electron-donating dye precursor and an electron-accepting compound to form color, and having a color density difference (ΔD) of 0.02 or more before and after pressurization at 0.05 MPa. When the colorless electron-donating dye precursor is included in microcapsules and the median diameter of the microcapsules on a volume basis is A μm, 5000 to 30000 microcapsules having a diameter of (A+5) μm or more are present per 2 cm×2 cm area. | 2010-07-22 |
20100184234 | REAGENT FOR MEASUREMENT OF CONCENTRATION OF LEAD, AND METHOD FOR MEASUREMENT OF CONCENTRATION OF LEAD - To provide a lead concentration determination reagent which realizes accurate, high-sensitivity, and simple-manner determination of the lead ion concentration (also referred to simply as “lead concentration”) of a sample solution in the presence of calcium ions, and a lead concentration determination method employing the reagent. | 2010-07-22 |
20100184235 | WELL PLATE FOR HOLDING A SAMPLE DURING ANALYSIS AND A METHOD FOR PREPARING A SAMPLE FOR ANALYSIS - A well plate ( | 2010-07-22 |
20100184236 | GUANOSINE TRIPHOSPHATE (GTP)-BINDING PROTEIN-COUPLED RECEPTOR PROTEIN, BG37 - The present inventors conducted a similarity search of the amino acid sequence of known G protein-coupled receptor proteins in GenBank, and obtained a novel human GPCR gene “BG37”, cDNA containing the ORF of the gene was cloned and its nucleotide sequence was determined. Moreover, novel GPCR “BG37” genes from mouse and rat were isolated. Use of the novel GPCR of the present invention enables screening of ligands, compounds inhibiting the binding to a ligand, and candidate compounds of pharmaceuticals which can regulate signal transduction from the “BG37” receptor. | 2010-07-22 |
20100184237 | Chemical reaction device, chemical reaction system, and chemical reaction method - A chemical reaction device is provided for a chemical reaction between molecules immobilized on a solid phase and molecules in a solution, and a chemical analysis device is also provided to capture molecules in the solution by molecules immobilized on the solid phase through a chemical reaction and subsequent measurement of the captured molecules. Reaction efficiency as well as sample throughput are thereby improved. The chemical reaction device and the chemical analysis device use a channel of a microfluidic device for a reaction vessel, and at least a particular molecule is immobilized on an interior surface and a fixed structure or a non-fixed obstacle against a flow is provided in the channel. In a typical reaction vessel having an enzyme immobilized on an interior surface of a capillary and glass beads functioning as an obstacle for the flow filled in the channel of the capillary, a reaction solution can move either in one direction or back and forth in two directions to thereby undergo a reaction with the enzyme immobilized on the interior surface. The flow of the reaction solution is not a laminar flow so that a reaction between the particular molecule immobilized and the reaction solution proceeds at high efficiency. | 2010-07-22 |
20100184238 | REACTION APPARATUS AND PROCESS - A new reaction apparatus including a capillary having an inner surface to which a probe molecule that specifically binds to an analyte is immobilized, allowing a short throughput time for completing the binding reaction, and achieving a highly efficient reaction using a small amount of a sample and a process of the reaction are provided. The reaction apparatus includes a capillary having an inner surface to which a probe molecule that specifically binds to an analyte is immobilized; a columnar magnetic body that is disposed in a fluid containing the analyte in the state that the fluid is placed in the capillary; end-fixing means for fixing one end of the columnar magnetic body in the capillary by a DC magnetic field; and end-moving means for moving the other end of the columnar magnetic body by an AC magnetic field so as to transfer the fluid. | 2010-07-22 |
20100184239 | MANUFACTURING METHOD OF SEMICONDUCTOR INTEGRATED CIRCUIT DEVICE USING MAGNETIC MEMORY - In the case where a laminated structure formed by laminating tunneling magnetoresistive films are processed by ion milling or the like, scattered substances of a material constituting the tunneling magnetoresistive film are deposited onto side walls of the laminated structure, or contaminate the inside of a device for processing. Accordingly, it has been difficult to manufacture a magnetic memory or a semiconductor device on which the magnetic memory is mounted, with stable characteristics. | 2010-07-22 |
20100184240 | SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SAME - Disclosed is a method of manufacturing a semiconductor device, which comprises the steps of: forming a hydrogen diffusion preventing insulating film covering capacitors; forming a capacitor protecting insulating film on the hydrogen diffusion preventing insulating film; and forming a first insulating film on the capacitor protecting insulating film by a plasma CVD method where, while a high-frequency bias electric power is applied toward the semiconductor substrate, a plasma-generating high frequency electric power is applied to first deposition gas containing oxygen and silicon compound gas. In the method, a condition by which moisture content in the capacitor protecting insulating film becomes less than that in the first insulating film is adopted as a film deposition condition for the capacitor protecting insulating film. | 2010-07-22 |
20100184241 | METHOD FOR MANUFACTURING THIN TYPE LIGHT EMITTING DIODE ASSEMBLY - A method is applied to manufacture a thin type light emitting diode (LED) assembly, and comprises the steps of: pressing a light-transmissible conductive film onto a carrier; etching an etched circuit on the light-transmissible conductive film to form an etched light-transmissible conductive film; bonding a LED chip on the etched light-transmissible conductive film to make the LED chip electrically connected with the etched circuit; covering the LED chip and the etched light-transmissible conductive film with a light-transmissible encapsulation layer to encapsulate the LED chip therein; and cutting the carrier to make the carrier be removed from the etched light-transmissible conductive film, so as to manufacture the thin type LED assembly. | 2010-07-22 |
20100184242 | METHOD OF IMPLANTATION - Provided is a method of implanting dopant ions to an integrated circuit. The method includes forming a first pixel and a second pixel in a substrate, forming an etch stop layer over the substrate, forming a hard mask layer over the etch stop layer, patterning the hard mask layer to include an opening between the first pixel and the second pixel, and implanting a plurality of dopants through the opening to form an isolation feature. | 2010-07-22 |
20100184243 | MASK APPLIED TO A WORKPIECE - A method of fabricating a workpiece is disclosed. A material defining apertures is applied to a workpiece. A species is introduced to the workpiece through the apertures and the material is removed. For example, the material may be evaporated, may form a volatile product with a gas, or may dissolve when exposed to a solvent. The species may be introduced using, for example, ion implantation or gaseous diffusion. | 2010-07-22 |
20100184244 | SYSTEMS AND METHODS FOR DEPOSITING PATTERNED MATERIALS FOR SOLAR PANEL PRODUCTION - Method and system for forming one or more predetermined patterns on a substrate for making a photovoltaic device. The method includes aligning at least a first droplet source with a substrate, dispensing one or more first droplets associated with one or more first materials from the first droplet source, and forming at least a first pattern of one or more second materials on the substrate by at least the first droplet source. Additionally, the method includes providing a first light beam incident on at least the first pattern, obtaining a first signal associated with the first pattern in response to the first light beam, processing information associated with the first signal, and determining one or more first characteristics of the first pattern based on at least information associated with the first signal. | 2010-07-22 |
20100184245 | METHOD FOR MANUFACTURING A BOLOMETRIC DETECTOR - The method is designed for manufacturing a bolometric detector equipped with a membrane suspended above a substrate by means of heat-insulating arms fixed to the substrate by anchoring points. The membrane has a heat-sensitive thin layer with a base comprising at least a semiconducting iron oxide. The method comprises at least a step of localized reduction and/or oxidation of the thin layer of semiconducting iron oxide to modify the degree of oxidation of the iron atom of a part of the thin layer of semiconducting iron oxide. | 2010-07-22 |
20100184246 | METHOD FOR MANUFACTURING SOLID-STATE IMAGE PICK-UP DEVICE - There is provided a method for manufacturing a solid-state image device which includes the steps of: forming a silicon epitaxial growth layer on a silicon substrate; forming photoelectric conversion portions, transfer gates, and a peripheral circuit portion in and/or on the silicon epitaxial growth layer and further forming a wiring layer on the silicon epitaxial growth layer; forming a split layer in the silicon substrate at a side of the silicon epitaxial growth layer; forming a support substrate on the wiring layer; peeling the silicon substrate from the split layer so as to leave a silicon layer formed of a part of the silicon substrate at a side of the support substrate; and planarizing the surface of the silicon layer. | 2010-07-22 |
20100184247 | Semiconductor Chip Having a Photodiode, Semiconductor Device and Manufacturing Method Thereof - A semiconductor chip that has a photodiode formed on it, a semiconductor device including the semiconductor chip, and manufacturing methods thereof. A second semiconductor region | 2010-07-22 |
20100184248 | Creation and Translation of Low-Relieff Texture for a Photovoltaic Cell - Low-relief texture can be created by applying and firing frit paste on a silicon surface. Where frit contacts the surface at high temperature, it etches silicon, dissolving silicon in the softened glass frit. The result is a series of small, randomly located pits, which produce a near-Lambertian surface, suitable for use in a photovoltaic cell. This texturing method consumes little silicon, and is advantageously used in a photovoltaic cell in which a thin silicon lamina comprises the base region of the cell. When the lamina is formed by implanting ions in a donor wafer to form a cleave plane and cleaving the lamina from the donor wafer at the cleave plane, the ion implantation step will serve to translate texture formed at a first surface to the cleave plane, and thus to the second, opposing surface following cleaving. Low-relief texture formed by other methods can be translated from the first surface to the second surface in this way as well. | 2010-07-22 |
20100184249 | Continuous deposition process and apparatus for manufacturing cadmium telluride photovoltaic devices - A continuous deposition process and apparatus for depositing semiconductor layers containing cadmium, tellurium or sulfur as a principal constituent on transparent substrates to form photovoltaic devices as the substrates are continuously conveyed through the deposition apparatus is described. The film deposition process for a photovoltaic device having an n-type window layer and three p-type absorber layers in contiguous contact is carried out by a modular continuous deposition apparatus which has a plurality of processing stations connected in series for depositing successive layers of semiconductor films onto continuously conveying substrates. The fabrication starts by providing an optically transparent substrate coated with a transparent conductive oxide layer, onto which an n-type window layer formed of CdS or CdZnS is sputter deposited. After the window layer is deposited, a first absorber layer is deposited thereon by sputter deposition. Thereafter, a second absorber layer formed of CdTe is deposited onto the first absorber layer by a novel vapor deposition process in which the CdTe film forming vapor is generated by sublimation of a CdTe source material. After the second absorber layer is deposited, a third absorber layer formed of CdHgTe is deposited thereon by sputter deposition. The substrates are continuously conveyed through the modular continuous deposition apparatus as successive layers of semiconductor films are deposited thereon. | 2010-07-22 |
20100184250 | SELF-ALIGNED SELECTIVE EMITTER FORMED BY COUNTERDOPING - An improved method of doping substrates, such as a solar cell, is disclosed. Conductors, such as metal lines, are often deposited on the surface of a substrate. In some embodiments, the conductivity of the substrate beneath the conductors is different than the conductivity of other regions of the substrate. Therefore, the conductors can serve as the mask for a subsequent blanket doping, which changes the conductivity of the surface of the substrate, except beneath the conductors. In some embodiments, an initial blanket doping is performed prior to the deposition of the conductors to create an initial uniformly doped region. | 2010-07-22 |
20100184251 | PLASMA INSIDE VAPOR DEPOSITION APPARATUS AND METHOD FOR MAKING MULTI-JUNCTION SILICON THIN FILM SOLAR CELL MODULES AND PANELS - A plasma inside vapor deposition apparatus for making silicon thin film solar cell modules including means for supporting a substrate, the substrate having an outer surface and an inner surface; plasma torch means located proximal to the inner surface for depositing at least one thin film layer on the inner surface of the substrate, the plasma torch means located a distance from the substrate; and means for supplying reagent chemicals to the plasma torch means, wherein the at least one thin film layer form the silicon thin film solar cell modules. | 2010-07-22 |
20100184252 | METHOD FOR MANUFACTURING ORGANIC THIN FILM TRANSISTOR AND ORGANIC THIN FILM TRANSISTOR - A method for manufacturing an organic thin film transistor having excellent characteristics by a simple process, and an organic thin film transistor are provided. In a manufacture method of an organic thin film transistor element having a gate electrode, a gate insulation layer, an organic semiconductor layer and a source electrode and a drain electrode on a support, the method is characterized by comprising a step for forming an organic semiconductor precursor layer by applying a solution in which an organic semiconductor precursor is dissolved, and a step for forming an organic semiconductor layer by converting the organic semiconductor precursor to an organic semiconductor by exposing the organic semiconductor precursor layer to a discharging gas in a plasma state. | 2010-07-22 |
20100184253 | PROCESS FOR MANUFACTURING THIN FILM TRANSISTOR - Disclosed is a process for manufacturing a thin film transistor, the process comprising the steps of providing an oxide semiconductor precursor solution for an oxide semiconductor layer in which an oxide semiconductor precursor is dissolved in a solvent, coating the oxide semiconductor precursor solution on a substrate to form an oxide semiconductor precursor layer, patterning the oxide semiconductor precursor layer so that the oxide semiconductor precursor layer remains at portions where the oxide semiconductor layer is to be formed, and heating the remaining oxide semiconductor precursor layer to form the oxide semiconductor layer. | 2010-07-22 |
20100184254 | Method for Manufacturing Semiconductor Device - An object is to provide a method for manufacturing a semiconductor device, in which the number of photolithography steps can be reduced, the manufacturing process can be simplified, and manufacturing can be performed with high yield at low cost. A method for manufacturing a semiconductor device includes the following steps: forming a semiconductor film; irradiating a laser beam by passing the laser beam through a photomask including a shield for shielding the laser beam; subliming a region which has been irradiated with the laser beam through a region in which the shield is not formed in the photomask in the semiconductor film; forming an island-shaped semiconductor film in such a way that a region which is not irradiated with the laser beam is not sublimed because it is a region in which the shield is formed in the photomask; forming a first electrode which is one of a source electrode and a drain electrode and a second electrode which is the other one of the source electrode and the drain electrode; forming a gate insulating film; and forming a gate electrode over the gate insulating film. | 2010-07-22 |
20100184255 | MANUFACTURING METHOD FOR PACKAGE STRUCTURE - A manufacturing method for package structure is provided. The manufacturing method includes the follow steps. Firstly, a substrate is provided. Next, a number of chips are provided. Then, the chips are electrically connected with the substrate. After that, the chips are encapsulated with a sealant, so that the chips and the substrate form a package. Then, the package is adhered by a vacuum force. Afterwards, the adhered package is singulated to form many package structures along the portion between adjacent two of airways. | 2010-07-22 |
20100184256 | RESIN SEALING METHOD OF SEMICONDUCTOR DEVICE - A resin sealing method of a semiconductor device includes: positioning semiconductor devices at predetermined positions of an adhesive layer formed on a support body and adhering the semiconductor devices thereto, sealing a part of each of the semiconductor devices with resin by curing a first seal resin in a fluidization state so as to fix the semiconductor devices adhered to the predetermined positions of the adhesive layer formed on the support body, setting the semiconductor devices fixed to the predetermined positions of the adhesive layer formed on the support body in a mold and sealing the exposure parts of the semiconductor devices exposed from the first seal resin with a second seal resin, and removing the support body and the adhesive layer from the semiconductor devices sealed with the resin. | 2010-07-22 |
20100184257 | METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE - There is provided a method of manufacturing a semiconductor device. The method includes the successive steps of: (a) providing a semiconductor substrate; (b) forming a plurality of semiconductor chips having electrode pads on the semiconductor substrate; (c) forming internal connection terminals on the electrode pads; (d) forming an insulating layer on the plurality of semiconductor chips to cover the internal connection terminals; (e) forming a metal layer on the insulating layer; (f) pushing a whole area of the metal layer to bring the metal layer into contact with upper end portions of the internal connection terminals; (g) pushing portions of the metal layer which contact the upper end portions of the internal connection terminals, thereby forming first recesses in the internal connection terminals, and thereby forming second recesses in the metal layer; and (h) forming wiring patterns by etching the metal layer. | 2010-07-22 |
20100184258 | METHOD AND APPARATUS FOR FORMING AN INTEGRATED CIRCUIT ELECTRODE HAVING A REDUCED CONTACT AREA - A method and an apparatus for manufacturing a memory cell having a nonvolatile resistive memory element with a limited size active area. The method comprises a first step of providing a dielectric volume and forming a plug opening within the dielectric volume. A recessed plug of a conductive material is then formed within a lower portion of the opening and a dielectric spacer is formed along the sidewalls of an upper portion of the opening. The spacer is cylindrical and has a central hole. A contact plug is subsequently formed within the central hole, the contact plug electrically coupled to the recessed plug. The contact plug can include a memory element or an additional memory element can be applied over the contact plug. | 2010-07-22 |
20100184259 | METHOD FOR FABRICATING A 3-D INTEGRATED CIRCUIT USING A HARD MASK OF SILICON-OXYNITRIDE ON AMORPHOUS CARBON - A method for fabricating a 3-D monolithic memory device. Silicon-oxynitride (Si | 2010-07-22 |
20100184260 | DUAL HIGH-K OXIDES WITH SIGE CHANNEL - A method and apparatus are described for integrating dual gate oxide (DGO) transistor devices ( | 2010-07-22 |
20100184261 | SEMICONDUCTOR DEVICE AND METHOD FOR MANUFACTURING THE SAME - There is provided a semiconductor device including: convex semiconductor layers formed on a semiconductor substrate via an insulating film; gate electrodes formed on a pair of facing sides of the semiconductor layers via a gate insulating film; a channel region formed of silicon between the gate electrodes in the semiconductor layers; a source extension region and a drain extension region formed of silicon germanium or silicon carbon on both sides of the channel region in the semiconductor layers; and a source region formed of silicon so as to adjoin to the opposite side of the channel region in the source extension region, and a drain region formed of silicon so as to adjoin to the opposite side of the channel region in the drain extension region in the semiconductor layers. | 2010-07-22 |
20100184262 | High electron mobility transistor having self-aligned miniature field mitigating plate and protective dielectric layer and fabrication method thereof - A semiconductor device is fabricated to include source and drain contacts including an ohmic metal sunken into the barrier layer and a portion of the channel layer; a protective dielectric layer disposed between the source and drain contacts on the barrier layer; a metallization layer disposed in drain and source ohmic vias between the source contact and the protective dielectric layer and between the protective dielectric layer and the drain contact; and a metal T-gate disposed above the barrier layer including a field mitigating plate disposed on a side portion of a stem of the metal T-gate. | 2010-07-22 |