29th week of 2022 patent applcation highlights part 7 |
Patent application number | Title | Published |
20220226157 | INFLATABLE EARPLUG SYSTEM - A deep insert, inflatable hearing protection earplug is provided that is easy for an untrained user to insert correctly, reliably providing high acoustic attenuation and remaining both secure and comfortable for long durations in a human ear. The earplug comprises a soft elastomer shell that forms a sealed volume filled with an inert fluid. The earplug can comprise a slender, flexible stem that is easily insertable into the ear canal when deflated. The proximal end of the earplug can be situated outside the ear canal, within the concha of the ear, and incorporates a bulb with a hemispherical, bistable cap. After inserting the shaft of the earplug into the ear canal, the wearer applies force with a finger to invert the cap, which transitions elastically from a convex to a concave external geometry, displacing a fixed volume of fluid to inflate a sheath that forms the outer covering of the stem, filling and sealing the ear canal. The sheath can be deflated by pulling on or otherwise engaging a release tab or other feature attached to the cap. | 2022-07-21 |
20220226158 | EXTERNAL EAR CANAL PRESSURE REGULATION SYSTEM - An external ear canal pressure regulation device including a fluid flow generator and an earpiece having a first axial earpiece conduit fluidicly coupled to the fluid flow generator, whereby the earpiece has a compliant earpiece external surface configured to sealably engage an external ear canal as a barrier between an external ear canal pressure and an ambient pressure. | 2022-07-21 |
20220226159 | LAYERED COMPOSITE FOR SCAR TREATMENT AND PREVENTION - A layered composite for scar treatment and prevention, the layered composite including a backing section; a drug matrix section; and a skin-interfacing section. The drug matrix section may be disposed between the back section and the skin-interfacing section. The drug matrix section may include pirfenidone in an amount of from about 1 to about 20 mg/cm | 2022-07-21 |
20220226160 | WOUND DRESSING - A method and apparatus are disclosed for dressing a wound. The apparatus comprises an absorbent layer for absorbing wound exudate, a liquid impermeable, gas permeable filter layer over the absorbent layer, a cover layer comprising at least one orifice and a first liquid and gas permeable transmission layer underlying the absorbent layer. The transmission layer is in fluid communication with the filter layer. | 2022-07-21 |
20220226161 | MEDICAL DRESSINGS WITH STIFFENING SYSTEMS - Medical dressings including stiffening systems fixedly attached to backing layers are described herein along with methods of using the medical dressings. The stiffening system is fixedly secured to the backing to limit flexing and stretching of the backing layer. Typically, the medical dressing and stiffening system is applied over a medical device that is secured to skin. The stiffening system covers some of the medical device and also extends beyond the medical device. The stiffening system stabilizes the medical device over the skin. | 2022-07-21 |
20220226162 | NEGATIVE PRESSURE WOUND TREATMENT SYSTEM AND METHOD - A negative pressure wound treatment system comprising a bandage portion and a negative pressure portion. The bandage portion includes a dressing portion in contact with a wound and a sealing layer positioned in contact with the dressing portion. The sealing layer includes an adhesive creating a seal around the wound. The negative pressure portion is in fluid communication with the bandage portion and includes a first valve and a second valve. The first valve is in fluid communication with the bandage portion and the negative pressure portion. The second valve is in fluid communication with the negative pressure portion and the surrounding environment. The negative pressure wound treatment system is configured to provide negative pressure to an area sealed by the bandage portion upon the actuation of the negative pressure portion. The negative pressure portion is configured to be actuated by compressing the negative pressure portion while walking. | 2022-07-21 |
20220226163 | COMPRESSION GARMENT - A compression garment that is operable to provide a compression force to a portion of the body of the wearer and wherein the outer surface thereof is configured to be washed and sanitized. The compression garment of the present invention if further configured to provide absorption of any moisture present adjacent the skin of the wearer during wearing of the compression garment. The compression garment includes an outer layer and an inner layer. The outer layer is manufactured from an expandable, waterproof and solvent resistant material. An inner layer is adjacent the outer layer and is manufactured from an absorbent material. A plurality of expansion joints are present in the inner layer so as to inhibit damage to the inner layer during expansion of the outer layer. The compression garment is washable so as to be properly cleaned and sanitized. | 2022-07-21 |
20220226164 | CARPAL TUNNEL WRIST BRACE - A brace for treating/preventing carpal tunnel injury including a body having a proximal end and a distal end defining s longitudinal direction, the body including a forearm support at the body proximal end, a wrist support coupled to the forearm support by a neck portion, the wrist support comprising a first palmar strap support, a first member and a second member extending from the wrist support in the longitudinal direction towards the distal end, a distal palmar support, a proximal palmar aperture, a palm band having a second palmar strap support, and a palmar strap, extending between a proximal end attached to the first palmar strap support to a distal end, the palmar strap configured to extend across a portion of the back of the hand and over a purlicue of the hand, the distal end of the palmar strap configured to removably attach to the distal palmar support. | 2022-07-21 |
20220226165 | METHOD OF AND APPARATUS FOR STABILIZING TUCKING-IN SIDE SEAMS OF ABSORBENT HYGIENE PANTS - The application relates to a method of and an apparatus for tucking a pair of opposing side seams ( | 2022-07-21 |
20220226166 | SENSOR FOR URINE AND STOOL DETECTION - A sensor for detecting urine and stool secretion mounted over two or more layers of garment, said sensor comprising: at least one light source configured to illuminate said garment; at least one photodetector configured to output an indication of the amount of light reflected from said garment; and an electronic circuit configured to detect said secretion by monitoring said output of said photodetector and identifying a temporal pattern being characteristic of said secretion event. | 2022-07-21 |
20220226167 | DETECTING DEVICE FOR DETECTING A STATE OF A DIAPER, DIAPER ACCOMMODATING THE DETECTING DEVICE - A device for detecting a state of a diaper includes a sensor unit with a conducting unit including at least two electrodes. The electrodes are configured to detect electrical parameters of their environment. A coupling portion is disposed on at least one end side of the conducting unit and is connectable to a measuring device. The conducting unit is attached to a carrier layer. The measuring device comprises an input portion being connectable to the sensor unit, and a processor configured to receive signals corresponding to values of the electrical parameters detected by the sensor unit and to process said signals. A power control means is configured to control electrical power supplied from a power supply, and a determination means is configured to determine whether a state of a diaper has changed. A transmitting means is configured to transmit information regarding the determined state change to a receiving means. | 2022-07-21 |
20220226168 | PATTERNED APERTURED WEBS - A patterned apertured web is disclosed. The patterned apertured web includes a plurality of land areas in the patterned apertured web and a plurality of apertures defined in the patterned apertured web. At least some land areas of the plurality of land areas surround at least some apertures of the plurality of apertures. The patterned apertured web has an Effective Open Area in the range of about 3% to about 30%, according to the Aperture Test herein. The patterned apertured web has a plurality of Interaperture Distances, according to the Aperture Test herein. The Interaperture Distances have a distribution having a median and a mean. | 2022-07-21 |
20220226169 | ABSORBENT ARTICLE - An absorbent article ( | 2022-07-21 |
20220226170 | Thong Panty Liner for Excessive Discharge - A disposable feminine menstrual pad with a tail (thong-type) structured to solve the problem of leakage of overflow while horizontal or vertical. The pad is a full size menstrual pad designed to be worn with a panty, and adhered to the crotch area by a strip of adhesive. The regular size (7-9 inch long) pad of any absorbency, but usually medium to heavy flow. A tail-like portion will have an additional 7-9 inches of absorbent material that is slim enough to fit in the anal canal with comfort. The tail-like portion will not have any adhesive and will naturally adhere to the area, further secured by the friction of the buttocks cheeks. | 2022-07-21 |
20220226171 | SYSTEM FOR POWERING MEDICAL IMAGING SYSTEMS - Mobile medical clinic vehicles are disclosed. An enclosure is connected to a chassis and accommodates medical equipment items for patients and healthcare providers to utilize. One or more electrical components receive electrical power output from a generator, when operated, and provide a first output at a first voltage to a first subset of the medical equipment items and a second output at a second voltage to a second subset of the medical equipment items. | 2022-07-21 |
20220226173 | Portable Body-Washing Apparatus - A portable body-washing apparatus is a self-supported, self-contained hygiene aid directed towards use in care-homes, hospitals, or other facilities typically tasked with assisted bathing of disabled persons. A mobile chassis supports an adjustable armature, a base chair segment, and at least one articulated chair segment to support a subject's body during washing. An onboard pump assembly and connected power supply feeds fluids from at least one fluid source through a plurality of conduits via a fluid selection source, enabling operators to select from various output modes, e.g., water, heated air, body wash, shampoo, et cetera. The plurality of conduits is connected to a plurality of outlet heads distributed across the base chair segment and at least one articulated chair segment to enable a full-body wash without requiring a caregiver to physically maneuver the patient. | 2022-07-21 |
20220226174 | ADJUSTABLE ANATOMICAL SUPPORT AND SEAT CUSION APPARATUS FOR WHEELING CHAIRS - An adjustable anatomical support and seat cushion apparatus for wheelchairs according to some embodiments of the disclosure includes a base member formed of at least one layer of a thermoplastic honeycomb material, a generally rectangular, resilient cushion member formed of upper, intermediate and lower layers of thermoplastic honeycomb material which are bonded together, and at least one pad removably insertable into a pocket in the lower layer. The base member is pivotally attached to the cushion member. The cushion member is rotatable between a non-parallel disposition and a parallel disposition relative to the base member. An open end of the pocket faces the base member when the cushion member is in the parallel disposition. | 2022-07-21 |
20220226175 | DRIFTING KART - Drifting karts in accordance with embodiments of the invention are described that include a front wheel drive train and rear caster wheels that can be dynamically engaged to induce and control drift during a turn. One embodiment of the invention includes a chassis to which a steering column is mounted, where the steering column includes at least one front steerable wheel configured to be driven by an electric motor, a battery housing mounted to the chassis, where the battery housing contains a controller and at least one battery, wiring configured to provide power from the at least one battery to the electric motor, two caster wheels mounted to the chassis, where each caster wheel is configured to rotate around a rotational axis and swivel around a swivel axis, and a hand lever configured to dynamically engage the caster wheels to induce and control drift during a turn. | 2022-07-21 |
20220226176 | A COMBINED LIFT AND TILT SYSTEM AND A WHEEL CHAIR WITH A BUILT-IN SEAT HOIST COMPRISING SUCH A SYSTEM - A combined lift and tilt system including a lower frame, an upper frame, a first lever arm rotatably connected to the lower frame, and a second lever arm rotatably connected to the first lever arm and to the upper frame and in sliding engagement with the lower frame. The system further including a first linear power source rotatably connected to the lower frame and to the first lever arm, and a second linear power source rotatably connected to the upper frame and to the second lever arm. | 2022-07-21 |
20220226177 | METHOD AND APPARATUS FOR INDICATING CONTINENCE STATE OF A PATIENT ON A BED - A patient support apparatus includes a frame and a mattress supported by the frame and arranged to support a patient thereon. A sensor is included to detect moisture on the patient and/or the patient support apparatus. The sensor produces signals indicative of the presence of moisture on the patient support apparatus. One or more alerts are output in response to the signals provided by the sensor to notify a caregiver of the presence of moisture on the patient support apparatus. | 2022-07-21 |
20220226178 | TRAUMA GURNEY WITH ENHANCED PATIENT TRANSFER CAPABILITIES - A trauma gurney includes a base connected to a frame by a vertical adjustment mechanism. The base is configured that it can be maneuvered over a receiving table. The frame holds a detachable platform suitable for the positioning of a patient thereon. Actuation of the adjustment mechanism allows the frame to be lowered and the patient platform to be detached. The patient platform is configured to be non-interfering with various procedures such as MRI procedures so the patient platform can remain with the patient after the patient has been transferred without adverse effects to the procedures. The patient platform can also be reattached to the frame after it has been removed. The trauma gurney beneficially allows a patient to be transferred from the gurney to another surface, such as for imaging, without requiring a conventional lateral transfer. Similarly, the trauma gurney allows a patient to be transferred back to the gurney. | 2022-07-21 |
20220226179 | APPARATUSES AND METHODS FOR PROVIDING AN ISOLATION AREA AROUND AN INDIVIDUAL - Apparatuses and methods for defining an isolation area around an individual. Such an apparatus includes a frame having two opposing and spaced-apart side walls, an interior region within an interior of the apparatus and defined by and between the side walls, and one or more connecting members spanning the interior region and coupling the opposing side walls. Isolation barriers are coupled to the frame and extend outwardly from the interior region. The isolation barriers are configured to define an isolation zone surrounding the interior region that corresponds with the isolation area around an individual located within the interior region. An opening is providing for access by the individual to and from the interior region within the frame. | 2022-07-21 |
20220226180 | Cart for Medical Equipment with Built-In Power Supply - An equipment cart for medical equipment, such as medical disinfection equipment, includes a base with a support surface for securing the equipment and casters that allow the equipment cart to be moved. A mechanical locking mechanism for the equipment may be provided. The equipment cart has an upright support connected to the base, and a work surface supported by the upright support and spaced from the base. A power system, including an uninterruptible power supply, is provided onboard the equipment cart and supplies AC power to one or more electrical outlets on the equipment cart in the form of generally sinusoidal AC power. | 2022-07-21 |
20220226181 | BACK THERAPY APPARATUS - A back-therapy apparatus for vertebral massage comprises at least one first manipulating element ( | 2022-07-21 |
20220226182 | WEARABLE ASSISTIVE DEVICE - The present invention relates to a wearable assistive device. | 2022-07-21 |
20220226183 | A SELF DRIVEN REHABILITATION DEVICE AND METHOD THEREOF - The present invention provides a compact, wearable and portable self driven rehabilitation device which is cost effective, light weight, portable, easy to use and customizable to fit as needed. It provides real-time mirroring effect for better visual feedback. | 2022-07-21 |
20220226184 | Compression Stocking with Adjustable Compression Pressure - The invention relates to a compression stocking with adjustable compression pressure for therapeutic compression of a limb, comprising a stocking element with a pressure compartment and a valve mechanism, the valve mechanism comprising: —a valve seat attached to the stocking element; —a valve lid attached to the valve seat or formed thereon, wherein the passage extends through the valve seat and the valve lid; —a valve provided in the passage and embodied to be movable between a closing position, in which the valve closes the passage airtightly, and a position allowing passage, in which the valve leaves the passage at least partially open; and —at least a connecting part between the valve and the valve seat and/or the valve lid for flexible attachment of the valve to the valve seat and/or the valve lid, wherein the at least one connecting part is embodied to urge the valve toward the closing position under bias. | 2022-07-21 |
20220226185 | APPARATUS FOR ACUPRESSURE BASED SELF-MASSAGE - An apparatus for self-massage of the vertebra includes a board and a frame. The board can be mounted onto the frame and the frame can be placed on ground. The board have several spherical balls protruding outwards from the top surface of the board and the spherical balls can freely rotate. A user can lie down on the board and push himself back and forth on the board wherein the spherical balls rub against the vertebra of the user. | 2022-07-21 |
20220226186 | STIMULATION DEVICE - Stimulation devices are disclosed. An example stimulation device includes a chamber which has a flexible wall portion. A drive unit of the stimulation device is in physical communication with the flexible wall portion so as to cause deflections of the flexible wall portion in opposing directions, thereby resulting in a changing volume of the chamber. The changing volume of the chamber results in modulated positive and negative pressures with respect to a reference pressure. An opening of the stimulation device is for applying the modulated positive and negative pressures to a body part. The stimulation device includes a control device for controlling the drive unit. | 2022-07-21 |
20220226187 | APPARATUS, SYSTEM, AND METHOD FOR TESTING AND EXERCISING THE PELVIC FLOOR MUSCULATURE - An apparatus for testing and exercising pelvic floor musculature, the apparatus comprising an elongate housing adapted for a pelvic floor aperture. The housing accommodates an oscillator and an accelerometer connected to a signal processor configured for communicating signals representative of values read from the accelerometer. A result is calculated from an applied oscillation and a response measured, and used for characterizing the musculature. In one embodiment the frequency resulting in the greatest response from the musculature is measured, and this frequency is applied during exercise. | 2022-07-21 |
20220226188 | VIBRATION GENERATOR - The invention relates to the field of transducers, in particular linear vibration generators. It concerns a vibration generator, devices comprising such a vibration generator and a related treatment method. | 2022-07-21 |
20220226189 | MASSAGE APPARATUS - A massage apparatus includes a main body having a surface, a plurality of massage rollers coupled to the main body, a textured region disposed on at least a portion of the surface of the main body, and an electronic module disposed within the main body. The electronic module includes at least one of a heating mechanism, a cooling mechanism, and a thermoelectric module. The electronic module is configured to heat, cool, and/or selectively heat and cool the main body and the plurality of massage rollers via the heating mechanism, the cooling mechanism, and the thermoelectric module, respectively. | 2022-07-21 |
20220226190 | SYNCHRONIZATION OF REPETITIVE THERAPEUTIC INTERVENTIONS - An external defibrillator system for assisting manual delivery of chest compressions and ventilations to a patient by a rescuer as cardiopulmonary resuscitation (CPR) includes a speaker, and a processor, memory, and associated circuitry coupled to the speaker. The processor is configured to initiate prompting for the chest compressions and the ventilations manually delivered to the patient by the rescuer as CPR, control the speaker to generate first auditory cues for the chest compressions, and control the speaker to generate second auditory cues for the ventilations with a different sound than the first auditory cues for the chest compressions. The first auditory cues and the second auditory cues assist the rescuer in timing the delivery of the chest compressions and the ventilations. | 2022-07-21 |
20220226191 | LOW TEMPERATURE VIALS AND VIAL ASSEMBLIES - Vials and vial assemblies for storing a medicament in low temperature environments are provided. In one exemplary embodiment, a vial is provided that includes a base portion and a finish portion. The finish portion has an outer surface and an inner surface, in which the inner surface defines a channel that is configured to receive a first portion of a deformable sealing member. The finish portion on the outer surface thereof includes a surface feature that is configured to engage with a second portion of the deformable sealing member. The surface feature is configured to remain engaged with the second portion of the deformable sealing member when the deformable sealing member contracts from a first configuration to a second configuration, thereby maintaining a seal between the finish portion and the deformable sealing member. | 2022-07-21 |
20220226192 | FLUID TRANSFER APPARATUS AND USE THEREOF - A fluid transfer apparatus is illustrated and described. The fluid transfer apparatus includes a fluid inlet, a fluid outlet and a fluid transfer device. The fluid inlet is associated with a fluid receptacle receiving portion, and the fluid receptacle receiving portion is configured to receive and engage at least a portion of a fluid receptacle. The fluid transfer apparatus is configurable between a first isolation state, in which the fluid transfer device is isolated from the fluid receptacle, such that the fluid container is fluidically isolated from the fluid inlet, to a second coupled state, in which the fluid transfer device is engaged with the fluid receptacle, such that the fluid receptacle is in fluid communication with the fluid inlet. | 2022-07-21 |
20220226193 | TWO-COMPONENT SYRINGE - A method for mixing a first substance of a first chamber of a syringe and a second substance of a second chamber of the syringe, wherein communication of the first chamber and the second chamber is blocked by a removable member, the method including positioning the first chamber at an elevation higher than the second chamber; removing the removable member to enable communication of the first substance with the second substance to form a mixture; positioning the second chamber at an elevation higher than the first chamber; and replacing the removable member to confine the mixture in the first chamber. | 2022-07-21 |
20220226194 | DRY DISCONNECT CARTRIDGE AND DUAL LUMEN NEEDLE FOR AUTOMATIC DRUG COMPOUNDER - Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes fluid pathways controllable by valves of the cartridge. A pump component within the cartridge is actuable to move fluid through the controllable fluid pathways. The cartridge includes a needle extending from a cartridge body and fluidly coupled to at least one of the controllable fluid pathways. The cartridge includes a vacuum bellows that surrounds the needle when the bellows is in an extended configuration. The vacuum bellows is compressible to expose the needle and generates a vacuum condition within the bellows when the bellows is extended from a compressed configuration to the extended configuration. The needle may be a dual-lumen plastic needle. | 2022-07-21 |
20220226195 | MASS MEASUREMENT APPARATUS FOR AUTOMATIC PROCESSING MACHINES AND MASS MEASUREMENT METHOD - A mass measuring apparatus includes a transferring and gripping device for removing an article from a seat of a movement device, holding the article in a measuring position, and then reinserting the article into the seat. The transferring and gripping device includes a gripping element for holding the article, an actuator for operating with an actuating signal on the gripping element to make the gripping element vibrate at a specific resonance frequency, a sensor for measuring a vibration response signal of the gripping element vibrating and supporting the article in the measuring position, a processing unit for receiving the vibration response signal and controlling the actuator to generate an actuating signal to make the gripping element vibrate at an operating resonance frequency, and then calculating a mass of the article by comparing the operating resonance frequency with the resonance frequency of the gripping element. | 2022-07-21 |
20220226196 | CLOSED-SYSTEM DRUG-TRANSFER DEVICES FOR SOLID DOSAGE FORMS - A closed-system grinding syringe ( | 2022-07-21 |
20220226197 | APPARATUS, DEVICE, AND METHOD FOR INFANT GAVAGE FEEDING - The disclosure includes embodiments of an apparatus, a device, and methods to transform an infant feeding bottle into an infant gavage feeding apparatus. According to an embodiment, an infant gavage feeding apparatus can include an infant feeding bottle, a gavage milk delivery component, a retaining ring, and a cord component. In another embodiment, infant milk dual-delivery device to transform an infant feeding bottle to an alternate nipple feeding and gavage feeding apparatus includes a gavage milk delivery component, a retaining ring, and a nipple receiving component. The gavage milk delivery component and the nipple receiving component can be positioned in a branched or a stacked configuration. The device can include a flow closure component and a controller to transition the milk flow for a gavage feeding and nipple feeding. The device can include a funnel to allow milk in the nipple to flow back into the infant feeding bottle. | 2022-07-21 |
20220226198 | REDOX CURING DENTAL COMPOSITION - A redox curing dental composition comprising:
| 2022-07-21 |
20220226199 | COMPOSITION AND METHOD FOR A ROOT CANAL FILLING - Compositions and methods for the synthesis of polymer foam materials, wherein the polymer foam materials include expandable polymers, which can be applied to many dental applications, such as for example but not limited to one or more of a filler, a sealer, a filling, and a root canal. The expandable polymers can include a cross linkable material that expands upon crosslinking. | 2022-07-21 |
20220226200 | Dental Materials For The Production Of Temporary Crowns And Bridges - Radically polymerizable dental material, which includes a combination of at least three thiourea derivatives, a hydroperoxide and preferably a transition metal compound as initiator system for the radical polymerization. | 2022-07-21 |
20220226201 | Process of Taking a Dental Impression with a Radiation-curable Composition Containing Mercapto-Functional Polyorganosiloxanes and VQM Resins - The invention relates to a process of taking a dental impression, the process comprising the steps of providing a radiation-curable dental impression composition, placing the radiation-curable dental impression composition in contact with dental tissue, applying radiation to the radiation-curable dental impression composition, letting the radiation-curable dental impression composition cure, removing the cured dental impression composition from the dental tissue, the radiation-curable dental impression composition comprising mercapto-functional polyorganosiloxane(s), VQM resin(s), photo-initiator(s) for initiating a curing reaction between, and optionally filler(s). The invention also relates to a cured dental impression obtained by radiation curing the radiation-curable dental impression composition, a kit of parts containing the radiation-curable dental impression composition and a dental impression tray filled with the radiation-curable dental impression composition. | 2022-07-21 |
20220226202 | COMPOSITION FOR FORMING COATING FILM - Provided is a composition for forming a coating film containing fine fibers, imparting an excellent durability to an obtained coating film. | 2022-07-21 |
20220226203 | SKIN-ATTACHABLE THIN FILM PATCH BASED ON A WATER-SOLUBLE NON-WOVEN FABRIC - The present invention is a thin film patch to be attached to the skin and used for skin treatment or skin care. In particular, a water-soluble polymer compound is formed by means of melt spinning, melt blowing or electrospinning, into a water-soluble non-woven fabric of which the average diameter of fiber is 5 μm or less. The water-soluble non-woven fabric is coated with a coating agent comprising an active ingredient with a skin treatment or skin care effect; therefore, a thin film having the total thickness of 50 μm and the basis weight of 20 gsm or less is formed, wherein the water-soluble non-woven fabric has an electrically conductive material deposited thereon to have electrical conductivity and is connected to an electrode so that a current can be applied thereto. | 2022-07-21 |
20220226204 | IMPROVEMENTS IN RELATION TO PERSONAL CLEANSING COMPOSITIONS - The invention relates to solid personal cleansing compositions which comprise a non-soap anionic surfactant, a carrier, an emulsifier, a humectant and water. The method entails preparing an emulsion of the components at an elevated temperature and cooling the emulsion to produce a block which can be re-melted and additised with colour, fragrance by downstream processors. The invention further relates to the emulsions and to methods for preparing the cleansing compositions. | 2022-07-21 |
20220226205 | Coated Particles and Their Uses - Provided are coated particles and methods of their use for providing healthcare benefits. More specifically, the present invention provides amino acid and/or polymer-coated particles, or particles coated with other materials, for binding to, or otherwise associating with, surfaces of the oral cavity. | 2022-07-21 |
20220226206 | COSMETIC APPEARANCE OF SKIN - The present invention is directed to targeted delivery of a cold slurry underneath a patient's skin to improve the cosmetic appearance of the skin. The “target” tissue can be muscle tissue that when cooled cannot contract and cause wrinkles/lines in the skin to appear. The target tissue can also be adipose tissue that causes overlying tissue to sag and form wrinkles/lines. The cold slurry induces apoptosis, and reduces the size of the tissue, and causes the connective tissue supporting the skin to thicken and tighten, thereby reducing wrinkles/lines. Skin can also be tightened with cold slurry injected into the dermis layer of the skin or within the layers of the oral mucosa making a cold slurry treatment ideal for reducing the appearance of baggy skin after a patient loses weight and or for treating obstructive sleep apnea. Cold slurry can also be used to treat cellulite and acne. | 2022-07-21 |
20220226207 | TEMPORARY TATTOO METHOD - The present invention relates to the temporary tattoo method applied on human body, furniture, and vehicles by use of neon paint that is visible at night and is not harmful for human health by way of spraying. | 2022-07-21 |
20220226208 | POLYUREA CAPSULES PREPARED WITH A POLYISOCYANATE AND CROSS-LINKING AGENT - Polyurea capsules that encapsulate active materials in polymeric walls resulting from the polymerization of an aromatic or aliphatic polyisocyanate and a cross-linking agent are provided as are consumer products containing said polyurea capsules and for methods for producing such capsules. | 2022-07-21 |
20220226209 | SAFE AND ECOFRIENDLY PERSISTENT SANITIZING GEL FOR TOPICAL APPLICATION - The invention discloses persistent antimicrobial protection of hands and/or surfaces of different objects using the hydro-alcoholic gel composition of the present invention. In particular, the invention provides water-resistant sanitizing hydro-alcoholic gel compositions based on ethyl alcohol, silver nanoparticles and fatty acids of Tung seed oil ( | 2022-07-21 |
20220226210 | NON-NANO PARTICLE SUNSCREEN COMPOSITION AND METHOD OF MAKING - A environmentally and user-safe non-nano particle zinc oxide sunscreen composition that is homogenous at rest with semi-sheer to transparent application including 20 to 30% by weight of zinc oxide, 50 to 70% by weight of an oil mixture and 10 to 30% by weight of a water-resistant wax comprising beeswax, calendula wax, or a mixture thereof. | 2022-07-21 |
20220226211 | SKINCARE COMPOSITIONS INCLUDING ZINC OXIDE - In an embodiment, the present disclosure relates to a composition for treating or preventing a skin condition. In some embodiments, the composition includes zinc oxide with a concentration between about 5 and 30 wt/wt %, coconut oil with a concentration between about 0.1 and 5 wt/wt %, tea tree oil with a concentration between about 0.00025 and 0.1 wt/wt %, citronella oil with a concentration between about 0.00025 and 0.1 wt/wt %, and lemongrass oil with a concentration between about 0.01 and 1 wt/wt %. In a further embodiment, the present disclosure pertains to a composition for treating or preventing a skin condition including zinc oxide with a concentration of about 24 wt/wt %, coconut oil with a concentration of about 1 wt/wt %, tea tree oil with a concentration of about 0.001 wt/wt %, citronella oil with a concentration of about 0.001 wt/wt %, and lemongrass oil with a concentration of about 0.08 wt/wt %. | 2022-07-21 |
20220226212 | EXTERNAL PREPARATION - [1] An external skin preparation for IR protection, an external skin preparation for heat insulation, an external skin preparation for photoaging prevention, an external preparation for skin temperature increase prevention, an external skin preparation for fatigue prevention and an external skin preparation for active oxygen production prevention, containing a tabular metal oxide (A) having a thickness of 30 to 360 nm, and [2] an external skin preparation containing a tabular metal oxide (A) having a thickness of 30 nm or more and 360 nm or less and an aspect ratio of 50 or more and 300 or less, and a nonvolatile oil (B) in a ratio by mass [(A)/(B)] of 0.05 to 5. | 2022-07-21 |
20220226213 | TOPICAL COMPOSITION FOR BALANCING MICROBIOTA OF SKIN - The present invention relates to Use of thymol or terpineol or an analogue of thymol or terpineol in a topical composition el for balancing microbiota of amenable skin, where balancing means selectively reducing microbial count of at least one genus of harmful microbes or of at least one genus of microbes that exhibit abnormal growth, while selectively increasing microbial count of at least one genus of beneficial microbes or of at least one genus of microbes whose numbers have abnormally reduced. | 2022-07-21 |
20220226214 | METHOD FOR STABILIZING RETINOIC ACID PRECURSORS AND A SKIN BENEFIT COMPOSITION WITH STABILIZED RETINOIC ACID PRECURSORS - A method for stabilizing retinoic acid precursors and a skin benefit composition with stabilized retinoic acid precursors are described. The composition has a retinoic acid precursor and a resorcinol to impede oxidation of the precursor in situ in the composition. | 2022-07-21 |
20220226215 | PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND - Photoprotective compositions comprising a dibenzoylmethane derivative, a merocyanine compound and a compound capable of accepting the triplet excited level energy of the dibenzoylmethane compound | 2022-07-21 |
20220226216 | HAIR TREATMENT METHOD - A hair treatment method comprising steps [A-1], [B], and [C], wherein the method is carried out in the order of [A-1]→[B]→[C], or in the order of [B]→[A-1]→[C]:
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20220226217 | Surfactant and Composition - The present invention provides a surfactant that has good foaming, foam quality, and solubility even having a pH equivalent to that of the skin, which is weakly acidic, has a low viscosity with high handleability, and can be useful in a product such as a personal care product, for example, a cosmetic. More specifically, the present invention provides a surfactant including an N-monounsaturated acyl acidic amino acid or a salt thereof, wherein the N-monounsaturated acyl is an acyl having 10 to 16 carbon atoms. | 2022-07-21 |
20220226218 | TOOTH WHITENING FILM, PROCESS OF MANUFACTURING THEREOF AND A METHOD OF USING SUCH A FILM - The present invention provides a tooth whitening film. The tooth whitening film comprises a dental bleaching agent comprising one or both of a non-hydrogen peroxide bleaching agent and hydrogen peroxide in a hydrogen peroxide-polymer complex, one or more polyphosphates, said one or more polyphosphates comprising one or more cyclic polyphosphates, one or more water soluble film-forming polymers, one or more plasticizers and one or more emulsifiers, wherein the film has a thickness from about 50 μm to about 500 μm. A kit comprising one or more such films having a thickness from about 50 μm to about 150 μm and a dental aligner is also provided. A process for the manufacture of the film is also provided, together with a method of using such a film to bleach teeth. | 2022-07-21 |
20220226219 | ANTIMICROBIAL COMPOSITIONS - A personal care composition comprising a cleansing phase comprising one or more cleansing surfactants comprising: i. a piroctone compound; ii. sodium benzoate; iii. a fragrance comprising a fragrance component selected from benzyl acetate, hexyl acetate, phenethyl alcohol, ethyl butyrate, eucalyptol, limonene, undecalactone, eugenol and mixtures thereof, in which the ratio of piroctone to sodium benzoate to the defined fragrance components iii) is from 1:1:1 to 1:130:130.10 | 2022-07-21 |
20220226220 | COMPOSITION FOR PREVENTING GRAY HAIR, PROMOTING BLACK HAIR AND PREVENTING, IMPROVING OR TREATING VITILIGO OR HYPOCHROMATISM COMPRISING FRUCTOSE 1,6-BISPHOSPHATE OR SALT, SOLVATE, STEREOISOMER OR HYDRATE THEREOF AS ACTIVE INGREDIENT - The present disclosure relates to a composition for preventing gray hair, promoting black hair and preventing, improving or treating vitiligo or hypochromatism, which contains fructose 1,6-bisphosphate or a salt, a solvate, a stereoisomer or a hydrate thereof as an active ingredient, and has been contrived to solve the problem of the prior art that appreciable effect cannot be achieved due to insignificant effect on melanin production. The composition of the present disclosure, which contains fructose 1,6-bisphosphate or a salt, a solvate, a stereoisomer or a hydrate thereof, provides superior effect of preventing gray hair, promoting black hair and treating vitiligo or hypochromatism. | 2022-07-21 |
20220226221 | METHOD FOR DYEING KERATINOUS MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, A CHROMOPHORIC COMPOUND AND A FILM-FORMING POLYMER I - A process for dyeing keratinous material is disclosed. The process includes applying an agent (a) and an agent (b) to the keratinous material. The agent (a) comprises (a1) at least one organic silicon compound. The agent (b) comprises (b1) at least one film-forming polymer and (b2) at least one first colorant compound selected from the group of pigments and/or direct dyes. A multi-component packaging unit is also disclosed, and comprises, separately packaged, a first container comprising an agent (a′), a second container comprising an agent (a″), and a third container comprising an agent (b). The agent (a′) comprises (a1) at least one organic silicon compound. The agent (a″) comprises at least 15% by weight of water. The agent (b) comprises (b1) at least one film-forming polymer, and (b2) at least one first colorant compound selected from the group of pigments and/or direct dyes. | 2022-07-21 |
20220226222 | COMPOSITIONS AND METHOD OF USE FOR HAIR STRAIGHTENING AND SHAPING - Peptides are provided herein, wherein the peptide bearing one or more amino acid sequence differences relative to SEQ ID NO: 1, with the amino acid sequence differences comprising at least one cysteine replacement. | 2022-07-21 |
20220226223 | Stable Silk Protein Fragment Compositions - A composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals. | 2022-07-21 |
20220226224 | DEODORANT COMPOSITION - Cosmetic formulation with deodorant activity for topical application including vitamin E or an ester thereof, starch, sodium bicarbonate, zinc oxide and a cosmetically acceptable carrier is disclosed. The vitamin E ester is preferably alpha-tocopherol acetate, n-propionate or linoleate and the vitamin E or ester thereof and is present in an amount of 5-40% by weight of the weight of the formulation. | 2022-07-21 |
20220226225 | STRUCTURED AQUEOUS COMPOSITIONS HAVING DISPERSED LIQUID BENEFIT AGENT DROPLETS - An aqueous composition, a sprayable composition containing the aqueous composition, and a method of making the aqueous composition are provided. The aqueous composition includes an aqueous phase and liquid benefit agent droplets discontinuously dispersed throughout the aqueous phase. The aqueous phase has a structurant system including a first polysaccharide and a second polysaccharide that is different from the first polysaccharide. The aqueous phase comprises less than 10,000 ppm surfactant. The aqueous composition exhibits a yield stress as determined by the RHEOLOGY TEST METHOD. | 2022-07-21 |
20220226226 | PERSONAL CARE SPRAY COMPOSITIONS AND METHODS COMPRISING TRANS-1-CHLORO-3,3,3-TRIFLUOROPROPENE - Disclosed are methods of applying a leave-on personal care treatment products comprising:
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20220226227 | DISSOLVABLE SOLID ARTICLE CONTAINING PRESERVATIVES - A dissolvable solid article, comprising: water soluble polymer; a surfactant; at least one selected from diaminocarboxylic acid chelants and salts thereof; at least one selected from aromatic carboxylic acids and salts thereof; a phenolic derivative; at least one selected from α, β-unsaturated Aliphatic Carboxylic Acids, salts, and derivatives thereof; at least one selected from non-aromatic organic alpha hydroxy acids and salts thereof; wherein the dissolvable solid article has a pH of from about 3 to about 5.5 when dissolved with 20 parts water to 1 part of the dissolvable solid article. The present invention provides dissolvable solid articles which provide preservative efficacy even after dissolution of the articles, while controlling the concentrations of preservative ingredients in the solid articles. | 2022-07-21 |
20220226228 | ORTHODONTIC CHEW AND COMFORT TAPE - An orthodontic chew for use with braces includes an elongated tubular member made of a chewable food grade silicone and including an ingredient that improves oral health during usage of braces. A comfort tape for use with braces includes a strip of flexible and stretchable material that is infused with an ingredient to improve oral care during treatment with braces. | 2022-07-21 |
20220226229 | PERSONAL CLEANSING COMPOSITIONS - An aqueous shampoo composition comprising: —a. a pre-formed emulsified silicone; b. a cationic deposition polymer; c. a hair substantive cationic conditioning polymer which is an APTAC polymer, having a molecular weight of less than 1 million Daltons, preferably selected from a homopolymer of (3-acrylamidopropyl) trimethyl ammonium chloride and a (3-acrylamidopropyl) trimethyl ammonium chloride/acrylamide copolymer; d. from 3 to less than 12 wt %, preferably 5 to less than 10 wt %, based on total weight of the composition, of a cleansing surfactant, which has an average degree of ethoxylation of E | 2022-07-21 |
20220226230 | Composition, Method of Making, Method of Use and System for Hair Health - Composition to increase the thickness of human hair, system including the composition, method of making the composition and method of using the composition. The composition comprises essential oil and carrier oil that is miscible with the essential oil. The essential oil comprises lemongrass oil, helichrysum oil, lavender oil, clary sage oil, cedarwood oil, eucalyptus oil, thyme oil , bergamot oil, tea tree oil, rosemary oil, and peppermint oil. The system comprises the composition, a container, and instructions for use of the composition. The composition is located inside the container and contained by the container. The instructions comprise an instruction to apply the composition to a human scalp. The method of making the composition comprises providing the carrier oil and adding the essential oil to the carrier oil. The method of using the composition comprises applying the composition to a human scalp. | 2022-07-21 |
20220226231 | AGRIMONY EXTRACT AS ANTI-POLLUTION AGENT - The present invention relates to the use of an agrimony extract as an anti-pollution agent and to cosmetic compositions containing this extract. | 2022-07-21 |
20220226232 | Dental formulation comprising xylitol and propolis - The present invention provides a dental formulation for the prevention and treatment of dental caries and dental hypersensitivity. The dental formulation is a toothpaste formulation comprising 25% of xylitol and 0.5% of propolis. | 2022-07-21 |
20220226233 | Dental Composition Comprising Potassium Nitrate and Propolis - The present invention provides a dental formulation for the prevention and treatment of dental caries and dental hypersensitivity. The dental formulation is a toothpaste formulation comprising 10% potassium nitrate and 0.5% of propolis; the propolis providing occlusion of tubules and the potassium nitrate providing depolarization of nerve membranes. | 2022-07-21 |
20220226234 | INJECTABLE COMPOSITION CONTAINING PRODRUG OF CASPASE INHIBITORS, AND PREPARATION METHOD THEREFOR - The present invention relates to an injectable pharmaceutical composition containing a prodrug of caspase inhibitors, and a preparation method therefor. More specifically, the present invention relates to an injectable pharmaceutical composition, and a preparation method therefor, the composition comprising, as an active ingredient, (2S,3S)-2-(fluoromethyl)-3-((R)-5-isopropyl-3-(isoquinolin-1-yl)-4,5-dihydroisoxazole-5-carboxamido)-5-oxotetrahydrofuran-2-yl acetate, which is a prodrug of caspase inhibitors, or a pharmaceutically acceptable salt or isomer thereof, and comprising, as a biocompatible polymer, microspheres containing poly(lactide-co-glycolide). | 2022-07-21 |
20220226235 | TOPICAL COPPER ION TREATMENTS AND METHODS OF MAKING TOPICAL COPPER ION TREATMENTS FOR USE IN VARIOUS ANATOMICAL AREAS OF THE BODY - A topical copper ion treatment in basic form composes a copper ion-containing solution composed of a biocompatible solution containing copper ions obtained by leaching of the copper ions from copper metal into the solution. The copper ion-containing solution can be combined with various carriers to form various forms of the copper ion treatment including creams, gels, lotions, foams, pastes, tampons, solutions, suppositories, body wipes, wound dressings, skin patches, and suture material. A method of making the copper ion-containing solution involves placing solid copper metal in a quantity of a biocompatible solution and maintaining the solution at a specified temperature for a predetermined period of time during which copper ions each from the copper metal into the solution, and thereafter separating the solution from the solid copper metal | 2022-07-21 |
20220226236 | Pulmonary Delivery of MRNA to Non-lung Target Cells - Compositions comprising mRNA formulated for pulmonary administration and related methods for delivery of the mRNA and/or encoded protein to a non-lung cell or tissue. The compositions and methods may be used to prevent or ameliorate the symptoms of diseases associated with the mRNA encoded protein. | 2022-07-21 |
20220226237 | Nutritional Compositions For The Management of Hyponatremia - The present invention involves novel urea compositions for oral administration, that are useful for treatment or management of hyponatremia. Also disclosed are novel methods of making the urea compositions. | 2022-07-21 |
20220226238 | METHODS AND COMPOSITIONS RELATING TO EMULSIONS COMPRISING FISH OIL AND/OR OMEGA-3 FATTY ACIDS - Described herein are emulsion compositions comprising fish oil and medium-chain triglycerides (MCT) and/or omega-3 fatty acids and medium-chain triglycerides (MCT). In some embodiments, the compositions further comprise, e.g., alpha-tocopherol, or one or more fatty acids. Further provided herein are methods of using the compositions, e.g., to provide nutrion, e.g., parenteral nutrition to a subject and/or to treat or prevent certain conditions described herein. | 2022-07-21 |
20220226239 | POLYMERIC MICELLE COMPLEXES, FORMULATIONS, AND USES THEREOF - The disclosure provides compositions of polymeric micelle complexes, as well as methods for preparing such compositions. Such compositions are suitable for pharmaceutical delivery of one or more ionic agents to cell interior, and can be used in therapy and/or diagnosis, for example, for treating cancer as well as other diseases depending on the ionic agent. | 2022-07-21 |
20220226240 | ORALLY ADMINISTRABLE COMPOSITION - An orally administrable micellar composition is provided. The composition comprises: i) at least one physiologically acceptable film forming agent in an amount ranging from about 30 to 80% by wt in a pharmaceutically acceptable aqueous solvent combined with ii) a micellar composition comprising a drug encapsulated in micelles of 50-1000 nm in size formed by micelle-forming compounds, in a pharmaceutically acceptable aqueous solvent. | 2022-07-21 |
20220226241 | STABLE ORGANIC CANNABINOID OIL BLEND FORMULATIONS - The present application is directed to thermally stable cannabinoid oil-containing topical formulations, such as lotions and balms. The formulations include sodium alginate and comprise greater than 95% USDA certified organic ingredients. These formulations may be used for dermal or transdermal application useful in the treatment of, e.g., pain. Also disclosed are methods of applying such formulations. | 2022-07-21 |
20220226242 | EXOSOME SYSTEMS, PRODUCTS AND METHODS - The present disclosure relates to exosome systems and compositions and preservative systems and compositions including systems and compositions including diatomic oxygen as well as methods of use and methods of manufacturing of them. | 2022-07-21 |
20220226243 | METHODS OF USING LIPID NANOPARTICLES FOR DELIVERING MODIFIED RNA ENCODING A VEGF-A POLYPEPTIDE AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME - The disclosure relates to nanoparticles comprising a lipid component and a modified RNA encoding a VEGF-A polypeptide. Aspects of the disclosure further relate to uses of nanoparticles comprising a lipid component and a modified RNA encoding a VEGF-A polypeptide, for improving wound healing in a subject. Some aspects of the disclosure relate to the topical administration of nanoparticles comprising a lipid component and a modified RNA. | 2022-07-21 |
20220226244 | MACROCYCLIC LIPIDS - Disclosed are cationic lipids which are compounds of Formula I. Cationic lipids provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly can be useful for treating various diseases, disorders and conditions, such as those associated with deficiency of one or more proteins. | 2022-07-21 |
20220226245 | STORAGE STABLE SINCALIDE FORMULATIONS - Disclosed herein are solid compositions that comprise sincalide and are storage stable and which lack a buffer, and optionally, also lack a surfactant/solubilizer, wherein such compositions are storage stable. Also disclosed herein are liquid compositions that comprise sincalide, wherein such compositions are storage stable, and may lack buffer and/or surfactant/solubilizer. Also provided are methods of making and administering the solid or liquid storage stable compositions to a patient in need of, e.g., for the treatment, prevention, and/or diagnosis of gall bladder- and/or pancreatic disorders; or other diagnostic imaging. | 2022-07-21 |
20220226246 | PHARMACEUTICAL COMPOSITION COMPRISING AXITINIB - The present invention relates to an immediate release tablet composition comprising axitinib form IV characterized by an XRPD pattern comprising the peaks at about 8.9, 12.0, 14.6, 15.2, 15.7, 17.8, 19.1, 20.6, 21.6, 23.2, 24.2, 24.9, 26.1 and 27.5±0.1 degrees 2θ, when measured with Cu Kα1 radiation and one or more pharmaceutically acceptable excipients, wherein the composition exhibits a dissolution rate between 40% and 70% in 30 minutes when tested in 900 ml 0.01 N hydrochloric acid pH 2.0 at 37° C., 75 rpm in a USP apparatus II. | 2022-07-21 |
20220226247 | STABLE HOT-MELT EXTRUDATE CONTAINING VALSARTAN AND SACUBITRIL - The present invention relates to a solid unit dosage form for oral administration (tablet or granules) containing a solid dispersion of valsartan and sacubitril in a polymeric matrix. The solid dispersion is prepared by hot-melt extrusion and may contain the active ingredients preferably in a non-crystalline state. LCZ696, (pseudo)polymorphic forms thereof as well as the individual drugs, e.g. valsartan disodium and sacubitril monosodium, may be subjected to the hot-melt extrusion process. | 2022-07-21 |
20220226248 | Pharmaceutical Dosage Forms and Method For Their Production - The invention relates to a method for producing solid or semi-solid dosage forms of pharmaceutical active ingredients. According to the method, an active-ingredient-free carrier structure is arranged in a 2D or 3D printing device and at least one pharmaceutical active ingredient is applied to at least one portion of the carrier structure by way of a 2D or 3D printing method carried out by the printing device. The invention also relates to semi-solid or solid dosage forms that are producible by the method according to the invention. | 2022-07-21 |
20220226249 | SOLID TABLET DOSAGE FORM OF RIDINILAZOLE - The present invention relates to solid tablet oral dosage forms of 2,2′-di(pyridin-4-yl)-1H,1′H-5,5′-bibenzo[d]imidazole (which may also be known as 2,2′-di-4-pyridinyl-6,6′-bi-1H-benzimidazole; 5,5′-bis[2-(4-pyridinyl)-1H-benzimidazole]; 2,2′-bis(4-pyridyl)-3H,3′H-5,5′-bibenzimidazole; or 2-pyridin-4-yl-6-(2-pyridin-4-yl-3H-benzimidazol-5-yl)-1H-benzimidazole), referenced herein by the INN name ridinilazole, and pharmaceutically acceptable derivatives, salts, hydrates, solvates, complexes, bioisosteres, metabolites or prodrugs thereof. | 2022-07-21 |
20220226250 | Additive Method For 3D Printing Active Ingredient-Containing Objects - The present invention relates to an additive method for the production of solid or semi-solid two- or three-dimensional objects containing one of more pharmaceutical active agent(s), as well as to the objects produced by said method, such as semi-solid or solid dosage forms or medical devices. The method is a three-dimensional printing method in which individual defined volume increments are printed, which can be selected essentially freely as regards contained active agents, used carrier materials, shape, size, color, concentrations of active agents, and arrangement in the produced object. | 2022-07-21 |
20220226251 | COMPOSITIONS OF PROTEINS WITH DIPEPTIDES AS STABILISING AGENTS - This invention relates pharmaceutical compositions comprising a protein as the active ingredient together with one or more dipeptides as stabilising agents, and optionally an enzyme inhibitor. The compositions are particularly useful for administration to the intestinal tract. | 2022-07-21 |
20220226252 | DELAYED DISINTEGRATION-TYPE CAPSULE AND METHOD FOR PRODUCING SAME - An object of the present invention is to provide a technique for delaying disintegration of a capsule by blending a certain component in a core of the capsule, and to increase the degree of freedom in capsule design. The present invention relates to a delayed disintegration-type seamless capsule that is a seamless capsule including a core, one or more intermediate layers formed on the core, and an outermost layer formed on the intermediate layers, wherein the core contains an active substance, an amphoteric surfactant, and a fat having a melting point of 40° C. or more, at least one layer of the intermediate layers contains a fat having a melting point of 45° C. or more, and the outermost layer contains a water-soluble natural polymer. The present invention also relates to a method for producing the same. | 2022-07-21 |
20220226253 | SAFE PARTICLES FOR THE INTRODUCTION OF USEFUL CHEMICAL AGENTS IN THE BODY WITH CONTROLLED ACTIVATION - This invention provides particles encapsulating active agent that do not produce functional effects or remove functional effects until they are triggered by contacting with at least one exogenous source. The particles in this invention minimize toxic effects to the body of the active agent and the material that interacts with an exogenous source as well as minimize body chemicals from degrading both the active agent and the material that interacts with an exogenous source inside the particle. | 2022-07-21 |
20220226254 | NEW DELIVERY SYSTEM FOR FAT SOLUBLE VITAMINS - The present invention relates to a new delivery system for fat-soluble vitamins. | 2022-07-21 |
20220226255 | ENCAPSULATION OF MESSENGER RNA - The present invention provides an improved process for lipid nanoparticle formulation and mRNA encapsulation. In some embodiments, the present invention provides a process of encapsulating messenger RNA (mRNA) in lipid nanoparticles comprising a step of mixing a mRNA solution and a lipid solution, wherein the mRNA solution and/or the lipid solution are at a pre-determined temperature greater than ambient temperature. | 2022-07-21 |
20220226256 | Hair care Terpinen 4-ol (T4O) composition for the treatment of demodex mites on scalp - The present invention is a hair care compositions, and more particularly to hair care compositions that contain a novel blend of natural ingredients which can be applied to the scalp and/or hair of a user for the treatment of scalp demodex which inturn helps to prevent hair loss and stimulates hair growth on male scalp. The composition includes at least one essential oil, a carrier oil and additives. One of the essential oils included is tea tree oil, the active ingredient of which is Terpinen-4-ol solution (T40). | 2022-07-21 |
20220226257 | USE OF CANNABINOIDS IN THE TREATMENT OF COMORBIDITIES ASSOCIATED WITH EPILEPSY - The present invention relates to the use of a specific composition of cannabidiol (CBD) in the treatment of comorbidities associated with epilepsy. In one embodiment the comorbidities are surprisingly found to be improved patients where there is as absence of reduction in seizures. The CBD used is in the form of a highly purified extract of cannabis such that the CBD is present at greater than 98% of the total extract (w/w) and the other components of the extract are characterised. In particular the cannabinoid tetrahydrocannabinol (THC) is present in an amount of from 0.02 to 0.1% (w/w). | 2022-07-21 |