29th week of 2015 patent applcation highlights part 26 |
Patent application number | Title | Published |
20150198501 | SYSTEMS AND METHODS FOR DETECTING LEAKS - Various embodiments disclosed herein relate to detecting leaks in a patient monitoring system. The system can include a fluid handling network configured to receive a fluid sample drawn from a patient and to deliver at least a portion of the fluid sample to an analyte measurement system. The system can isolate at least a portion of the fluid handling network, can apply pressure to the at least a portion of the fluid handling network, can measure the pressure in the at least a portion of the fluid handling network, and can determine whether a leak is present in the at least a portion of the fluid handling network based at least in part on the measured pressure. | 2015-07-16 |
20150198502 | METHODS AND SYSTEMS FOR AUTOMATED BRIDGE STRUCTURAL HEALTH MONITORING - In-situ methods and systems for determining bridge load ratings under ambient traffic are provided. These may include, for example, by installing one or more strain gauges on one or more bridge girders a batch of strain readings may be acquired from the one or more strain gauges. From the batch of strain readings, one or more strain time histories may be randomly sampled based, for example, on a girder peak strain. One or more vehicles may be randomly selected based on the one or more stored vehicle parameters by accessing a database with one or more stored vehicles and stored vehicle parameters. A bridge load rating model may be calibrated based on the one or more randomly sampled strain time histories and the randomly selected one or more vehicles for acquiring, in one embodiment, a bridge load rating distribution. | 2015-07-16 |
20150198503 | METHOD AND SYSTEM FOR MEASURING AN OPTICAL LOSS VALUE OF AN OPTICAL FIBER LINK - The reflectometric method for measuring an optical loss value of an optical fiber link generally comprises: obtaining at least one bias value being indicative of a bias induced by differing backscattering characteristics of a first optical fiber length and a second optical fiber length; propagating at least one test signal serially into the first optical fiber length, the optical fiber link and the second optical fiber length; monitoring at least one return signal resulting respectively from the propagation of the at least one test signal; and determining the optical loss value based on the at least one return signal and the at least one bias value. | 2015-07-16 |
20150198504 | ENGINE PROBE SYSTEM - An engine probe system for monitoring a moving engine element. The probe system includes a capacitive sensor ( | 2015-07-16 |
20150198505 | SYSTEM AND METHOD FOR ADJUSTMENT RESPONSE ANALYSIS - The present disclosure relates to a method to determine, from a measured result and an assumed adjustment set, the probability that a permutation to the assumed adjustment set was implemented or other error, such as a sensor error, is occurring. The determination of probability of a permutation of the adjustment set may be based on the error between the predicted response and the measured actual response for the assumed adjustment set and permutations of the assumed adjustment set. A number of statistical comparisons may be performed between the assumed adjustment set and the permutation sets to determine which are closer to the measured actual response. A probability value may be assigned to each adjustment set as to the likelihood of their having been implemented. | 2015-07-16 |
20150198506 | ROTATION DRUM ALIGNMENT ASCERTAINING DEVICE - In order to ascertain the placement of a rotation drum relative to the shaft axis of a spindle assembly, an alignment ascertaining device according to the present invention comprises a body portion made mountable on a mounting surface formed horizontally on the spindle assembly, the body portion having a guide face in the direction at right angles to the mounting surface; a linear guide portion mounted in an upward and down ward direction on a guide face; a slider mounted via a rolling member to the linear guide portion, the slider made movable in a direction in which the linear guide portion is installed; an arm member whose proximal end portion is attached to the slider and whose distal end portion extends toward the rotation drum; and a dial gauge mounted on the distal end portion of the arm member. | 2015-07-16 |
20150198507 | Increased Pressure for Emergency Steering Pump Startup Test - A method of determining readiness of an emergency steering pump system is provided. The method may include the steps of detecting a startup condition; determining a standby pressure provided by a primary pump and a margin pressure to be provided by a secondary pump; engaging the secondary pump for a predefined duration based on the standby pressure and the margin pressure; and determining readiness based on a cumulative pressure of the standby pressure and the margin pressure as compared to a predefined threshold corresponding to load demand. | 2015-07-16 |
20150198508 | SAMPLE PREPARATION DEVICE, CELL ANALYZER, AND FILTER MEMBER - A sample preparation device includes: a filter member including a filter configured to separate cells being an analysis target from other components in a sample; a first receptacle and a second receptacle configured to be connected to each other via the filter; a third receptacle capable of holding the sample therein; a negative pressure section configured to apply a negative pressure into the second receptacle, thereby to move the sample in the third receptacle toward the filter via the first receptacle, and thereby to move components other than the analysis target into the second receptacle via the filter; and a positive pressure section configured to apply a positive pressure from the second receptacle side to the filter to which cells being the analysis target are attached. | 2015-07-16 |
20150198509 | METHOD FOR AUTOMATED PROCESSING AND EMBEDDING OF TISSUE SAMPLES - An automated machine for handling and embedding tissue samples contained on microtome sectionable supports. The machine includes an input member configured to hold a plurality of the microtome sectionable supports prior to a tissue embedding operation. An output member is configured to hold a plurality of the microtome sectionable supports after the tissue embedding operation. A cooling unit is configured to hold at least one of the microtome sectionable supports during the tissue embedding operation. A motorized carrier assembly is mounted for movement and configured to hold at least one of the microtome sectionable supports. The carrier assembly moves the support from the input member to the cooling unit and, finally, to the output member. A dispensing device dispenses an embedding material onto the microtome sectionable support and at least one tissue sample carried by the microtome sectionable support during the embedding operation. | 2015-07-16 |
20150198510 | PREPARING BIOLOGICAL SAMPLES FOR ANALYSIS - Methods and devices for preparing a biological sample for analysis are described. The biological sample from an organism has at least macromolecule having a primary structure that naturally degrades after the sample is removed from the organism. The method includes causing the biological sample to adopt a shape to permit rapid and uniform heating. The shaped sample is then rapidly and uniformly heated, thereby altering a secondary structure of the macromolecule while preserving its primary structure. | 2015-07-16 |
20150198511 | APPARATUS AND METHOD FOR PRODUCING ANALYSIS SAMPLES - Apparatus for producing analysis samples for X-ray fluorescence spectroscopy that includes a crucible holder that supports a crucible with sample material and a casting dish that is provided underneath the crucible. The crucible is tiltably mounted in the crucible holder and the crucible holder along with crucible holder and the casting dish is handled as a single unit for loading and unloading the oven. The oven has a floor on which the crucible holder is positioned upright, and the portion of the floor receiving the crucible holder is designed as a turntable which imparts oscillating rotational motion to the crucible holder and crucible holder. The method entails placing the crucible with the sample material in the crucible holder while they are outside the oven and then placing entire crucible unit loosely in the oven. | 2015-07-16 |
20150198512 | Static Gel Strength Measurement Apparatus and Method - A fluid properties measurement apparatus for use with a conventional high temperature high pressure test cell includes a load cell assembly and a drive motor that drives a rotating shaft magnetically connected to a vane assembly having multiple vane elements, wherein the motor rotates in response to reactive forces of a fluid sample and the load cell assembly measures reactive forces of the sample. In one embodiment, a stepper motor allows for precise shaft rotation. | 2015-07-16 |
20150198513 | METHOD OF CRITICAL DISPLACEMENT FORECAST BASED ON THE DEFORMATION FAILURE MECHANISM OF SLOPE - In a method of critical displacement forecast based on the deformation failure mechanism of slope, a sliding surface displacement, a calculation based on status stability factors and a slope surface displacement are determined, and applied for forecast based on a thrust-type slope deformation mechanism, a key compartment division, a relation between stress and strain mechanics properties of sliding surface of geo-material, and an analysis of evolution characteristics at different points of the sliding surface. The method provides advantages of determining deformation values at different points of a sliding surface, a slope body and a slope surface during slope failures; describing the process of a progressive failure, deformations and force changes of a slope; combining slope monitoring values to perform the stability analysis and the calculation of the magnitude of the stability factors in different deformation statuses of the slope; and assessing the durability of protective measures to the slope. | 2015-07-16 |
20150198514 | METHODS AND APPARATUS TO DETERMINE INTEGRITY OF COMPOSITE STRUCTURES - Apparatus and methods to determine structural integrity of composites are described herein. One described example method for determining sufficiency of structural integration of a composite structure for an aircraft includes applying a fluid droplet to a surface of the composite structure, determining a three-dimensional contact angle between the surface and a portion of the droplet, comparing the three-dimensional contact angle to a threshold angle, and determining whether the structural integration of the composite structure is sufficient based on the comparison. | 2015-07-16 |
20150198515 | RAPID MEASUREMENT OF FORMED BLOOD COMPONENT SEDIMENTATION RATE FROM SMALL SAMPLE VOLUMES - Devices and methods are described for measuring formed blood component sedimentation rate. Some of the methods may use (1) centrifugal techniques for separating red blood cells from plasma and (2) video and/or still imaging capability. Both may be used alone or in combination to accelerate formed blood component sedimentation and to measure its rate. In one example, the method may advantageously enable rapid measurement of sedimentation rate using small blood sample volumes. Automated image analysis can be used to determine both sedimentation rate and hematocrit. Automated techniques may be used to compensate for effects of hematocrit on uncorrected sedimentation rate data. | 2015-07-16 |
20150198516 | VACUUM APPARATUS AND METHOD OF MONITORING PARTICLES - A vacuum apparatus includes a vacuum chamber, first sensor units disposed in the vacuum chamber facing a deposition direction of particles, and second sensor units disposed in the vacuum chamber, each disposed on a corresponding first sensor of the first sensor units facing the deposition direction, wherein the first sensor units are configured to sense a pressure in the vacuum chamber and an absorption amount of the particles adsorbed to the first sensor units, and the second sensor units are configured to sense the pressure in the vacuum chamber. | 2015-07-16 |
20150198517 | Method and System for Microfluidic Particle Orientation and/or Sorting - A system for orienting particles in a microfluidic system includes one or more radiation pressure sources arranged to expose particles to radiation pressure to cause the particles to adopt a particular orientation in the fluid. A system for sorting particles in a microfluidic system includes a detection stage arranged to detect at least one difference or discriminate between particles in the fluid flow past the detection stage, and one or more radiation pressure sources past which the particles move sequentially and a controller arranged to switch radiation energy to cause a change in direction of movement of selected particles in the fluid flow to sort the particles. The particles may be biological particles such as spermatazoa. The radiation pressure may be optical pressure and may be from one or more waveguides which may extend across a channel of the microfluidic system. | 2015-07-16 |
20150198518 | CATHODIC PROTECTION REFERENCE CELL ARTICLE AND METHOD - An article for enabling determination of corrosion m a structure which is located in an environment and is subject to corrosion in the environment. The article comprises a cathodic protection reference cell. The cathodic protection reference cell is able to be located in the environment at a location different from the location of the structure in the environment, and is able to be electrically coupled to the structure. The cathodic protection reference cell comprises a housing, and a reference electrode located in the housing. The reference electrode is able to be electrically connected to the structure which is located in the environment, to form a reference electrode-structure circuit. The reference electrode functions as an electrochemical cell, which enables measurement of the voltage drop which represents the structure-to-environment potential, for enabling the determination of the extent of cathodic protection of the structure. | 2015-07-16 |
20150198519 | CORROSION SENSING SYSTEMS AND METHODS INCLUDING ELECTROCHEMICAL CELLS ACTIVATED BY EXPOSURE TO DAMAGING FLUIDS - Systems and methods that can monitor corrosion are disclosed herein. In certain embodiments, the systems and methods can offer the capability of corrosion monitoring in remote locations without intrusion of wired connections. | 2015-07-16 |
20150198520 | SYSTEMS AND METHODS FOR CREATING ALTERED ADHESIVE BONDS - Disclosed are systems and methods of creating altered adhesive bonded joints between metal or composite substrates, including bonds that are weaker in strength than selected reference bonds. One method of creating an altered adhesive bond includes providing a first substrate and a second substrate, selecting a manufacturing process having a plurality of steps designed to produce a desired, or reference, adhesive bond having a desired strength, and selectively altering at least one of the plurality of steps during performance of the manufacturing process to produce an altered bond between the first substrate and the second substrate, the altered bond having an altered strength that is weaker than the strength of the desired adhesive bond. The systems may include systems that may be utilized to create the altered adhesive bonds and/or test standards. | 2015-07-16 |
20150198521 | MODIFIED MEASURING CUVETTE - A measuring cuvette ( | 2015-07-16 |
20150198522 | METHOD AND APPARATUS FOR IMAGE-BASED COLOR MEASUREMENT USING A SMART PHONE - An apparatus for assisting in measuring a color of a target includes an enclosed housing having a first aperture formed in a first end and a second aperture formed in an opposite second end and aligned concentrically with the first aperture, an array of light emitting diodes positioned inside the housing, between the first aperture and the second aperture, and an array of reference colors having known reflectance spectra, the array of reference colors being removably positioned inside the housing, between the array of light emitting diodes and the second aperture. | 2015-07-16 |
20150198523 | AUTOMATIC FIXTURE REMOVAL USING ONE-PORT MEASUREMENT - Scattering parameters of a test fixture having a first port and a second port are measured by providing a test instrument; outputting a one-port reflection test signal from the test instrument to the first port with the second port terminated in a reflective termination having a known reflection coefficient, and receiving at the test instrument a one-port reflection measurement signal from the first port; subjecting the one-port reflection measurement signal to first time gating to generate a first time-gated measurement signal, the first time gating using a first gating function temporally disposed about the first port; subjecting the one-port reflection measurement signal to second time gating to generate a second time-gated measurement signal, the second time gating using a second gating function temporally disposed about the termination; and deriving the scattering parameters from the first time-gated measurement signal and the second time-gated measurement signal. | 2015-07-16 |
20150198524 | NEAR FIELD METROLOGY - Metrology systems and methods are provided herein, which comprise an optical element that is positioned between an objective lens of the system and a target. The optical element is arranged to enhance evanescent modes of radiation reflected by the target. Various configurations are disclosed: the optical element may comprise a solid immersion lens, a combination of Moiré-elements and solid immersion optics, dielectric-metal-dielectric stacks of different designs, and resonating elements to amplify the evanescent modes of illuminating radiation. The metrology systems and methods are configurable to various metrology types, including imaging and scatterometry methods. | 2015-07-16 |
20150198525 | AUTOMATIC ANALYZER - To be adapted to various types of latex reagents for detecting scattered light and thereby measuring agglutination reactions with high sensitivity while sufficiently ensuring integration time. To be adapted to various types of latex particles of different particle sizes, a plurality of light receivers are arranged in a plane perpendicular to the direction of cell movement by rotation of a cell disk. To ensure sufficient integration time, the angle between the optical axis of the irradiation light and each of a plurality of optical axes of scattered light viewed from above the cell is made equal to or less than 17.7° including a mounting error. | 2015-07-16 |
20150198526 | DIFFERENTIAL DETECTION FOR SURFACE PLASMON RESONANCE SENSOR AND METHOD - A differential measurement design employing two nearly collinear optical beams provides surface plasmon polariton resonance (SPR) sensors and a corresponding method of increased dynamic range and signal to noise ratio. The differential measurement device and method based on wavelength interrogation, employs a single incident polarization state, and is combined with a 2-D nanohole array for operation at near-normal incidence, where this approach offers a decrease in the measurement time. | 2015-07-16 |
20150198527 | PERFORATED-STRUCTURE BODY, MANUFACTURING METHOD THEREFOR, AND MEASUREMENT APPARATUS AND MEASUREMENT METHOD - A perforated-structure body having a plurality of apertures that penetrate from a first main surface to a second main surface of a perforated plate. Support substrates are stacked on at least one of the first main surface and the second main surface of the perforated plate so as to define a portion through which at least one of the apertures is exposed. | 2015-07-16 |
20150198528 | ASSAY DETECTION SYSTEM - An assay system including reagents and devices for conducting rapid, high sensitivity analyte assays, including multiplexed assays, is described. The reagents and devices are adapted for performing time-resolved signal detection with low background due to non-specific binding. Also described are apparatus for use in measuring a luminescent property of a sample. The apparatus can use light emitting diodes for emitting radiation to excite the sample, under the control of a control signal. A signal generator generates the control signal for modulating the intensity of the emitted radiation. The control signal has a first component at a first frequency with a period that is less than, or of the same order as, an expected characteristic time constant of the luminescent property. The control signal has a second component at a second frequency with a period that is greater than the expected characteristic time constant of the luminescent property. A photosensor receives the radiation luminesced from the sample as a result of the excitation and detector circuitry generates a detection signal representing an intensity of the received radiation, and demodulates the detection signal to produce a signal representing the luminescent property of the sample. | 2015-07-16 |
20150198529 | SCINTILLATOR PANEL AND RADIATION DETECTOR - In a scintillator panel, a glass substrate with the thickness of not more than 150 μm serves as a support body, thereby achieving excellent radiotransparency and flexibility. Furthermore, in this scintillator panel, an organic resin layer is formed so as to cover the entire surface of the glass substrate. This reinforces the glass substrate, whereby the edge part thereof can be prevented from chipping or cracking. Furthermore, stray light can be prevented from entering a side face of the glass substrate and, since the organic resin layer is formed on the entire surface, it becomes feasible to suppress warping of the glass substrate due to internal stress after formation of a scintillator layer. | 2015-07-16 |
20150198530 | Method for Producing Optically Stimulated LuminescenE Dosage Detection Crystal - A method for producing an optically stimulated luminescene (OSL) dosage detection crystal is disclosed, where an Al | 2015-07-16 |
20150198531 | Long Range Product Authenticator - Methods and apparatus for a long range product authenticator. An example apparatus includes a sample that produces a luminescent emission in response to illumination by electromagnetic radiation with a first wavelength, a laser to illuminate the sample with electromagnetic radiation that has the first wavelength, wherein the laser illuminates the sample during a first duration of time and does not illuminate the sample during a second duration of time, a photo element to detect the luminescent emission of the sample during the second duration of time and a lens to focus the luminescent emission of the sample onto the photo element. | 2015-07-16 |
20150198532 | BIOMARKER DETECTING PROBE CAPABLE OF EARLY DETECTION AND PRECISE QUANTIFICATION AND USE THEREOF - The invention relates to a biomarker detecting probe which is capable of early detection of a biomarker and precise quantification thereof at the same time, and a method of detecting a biomarker using the same. More particularly, it relates to a biomarker detecting probe comprising a ferritin protein, and a targeting antibody linked with a fluorescent material, superparamagnetic nano particle, and conductive particle, and a method of detecting a biomarker using the same. | 2015-07-16 |
20150198533 | LUCIGEN YELLOW (LucY), A YELLOW FLUORESCENT PROTEIN - Described herein are isolated polynucleotides that encode a fluorescent protein which is at least 80% sequence identical to a protein selected from the group consisting of SEQ. ID. NOS: 2, 4, 6, 10, 14, 18, 22, 26, 30, 34, 38, 42, 46, 50, 54, 58, 62, 66, 70, and 74. Also described are expression constructs containing the polynucleotides, transformed host cells containing the expression constructions, the encoded fluorescent proteins themselves, and methods of using the nucleotides and encoded fluorescent proteins for bioanalytical research. | 2015-07-16 |
20150198534 | METHODS FOR MEASURING CONCENTRATIONS OF ANALYTES IN TURBID SOLUTIONS BY APPLYING TURBIDITY CORRECTIONS TO RAMAN OBSERVATIONS - A method of measuring the concentration of an analyte in a turbid solution containing the analyte and a solvent is disclosed. The method includes determining a turbidity value for the turbid solution based on a Raman line intensity calibration data set for the solvent. The method further includes determining turbidity correction factor based on the turbidity value and a Raman line calibration data set for the analyte and applying the turbidity correction factor to the Raman line intensity of the analyte in the turbid solution and calculating a turbidity-corrected Raman line intensity for the analyte in the turbid solution. The turbidity-corrected Raman line intensity of the analyte in the turbid solution is then used to determine the concentration of the analyte in the turbid solution utilizing previously developed calibration data sets relating Raman line intensity to analyte concentration in solutions of negligible turbidity. | 2015-07-16 |
20150198535 | LIGHT MEASURING APPARATUS EMPLOYING OPTICAL ELECTRIC FIELD ENHANCING DEVICE - Using an optical electric field enhancing device including a fine uneven structure made of gold formed on the front surface of a transparent substrate, illumination light of a wavelength in the range from 400 to 530 nm is applied at least to an analyte, positional information of the analyte is detected by a position detection unit disposed on the rear surface side of the optical electric field enhancing device, and excitation light is applied to the detected position by an excitation light application unit. Signal light emitted from the analyte when the excitation light is applied is detected from the rear surface side of the transparent substrate. | 2015-07-16 |
20150198536 | OPTICAL ELECTRIC FIELD ENHANCING DEVICE, METHOD OF MANUFACTURING THE SAME, AND MEASURING APPARATUS EMPLOYING THE SAME - An optical electric field enhancing device is used with a measuring method which includes two-dimensionally scanning a surface in in-plane direction of the surface to detect, from the rear surface side of the device, signal light emitted from each scanning point when excitation light is applied, and obtaining a two-dimensional signal image on the surface based on the detected signal light. The device includes a transparent substrate, a marker pattern directly formed on the transparent substrate and extending in a direction non-parallel to the main scanning direction of the two-dimensional scanning, and fine uneven structures formed on the marker pattern and the transparent substrate where at least the surface is made of a metal film. | 2015-07-16 |
20150198537 | SCREENING APPARATUS AND SCREENING METHOD - A screening apparatus includes a light permeable measurement chip having a well retaining a liquid including microparticles, a measuring section acquiring optical information of the microparticles obtained by illuminating the microparticles, an analyzing section that extracts optical information of the microparticles, a receiving plate receiving a microparticle selectively picked up from the measurement chip, a moving section moving the measurement chip and the receiving plate against the measuring section, and a collecting section for collecting a microparticle by sucking with the suction-ejection capillary and ejecting on the receiving plate. A distal-end outer dimension of the capillary is greater than a width of the well. The capillary sucks the target microparticle at a position where the distal end of the capillary and the measurement chip are spaced by a predetermined distance and a central axis of the distal end of the capillary and a central axis of the well are mutually displaced. | 2015-07-16 |
20150198538 | METHOD AND APPARATUS FOR ANALYSIS OF ALKYLATION CATALYST COMPOSITION - Apparatus and method for the determination of weight fractions of hydrocarbons, water and acid in the acid catalyst phase of petroleum refinery alkylation catalyst streams by flowing the acid catalyst phase through a density detector and a spectrometer cell so that the determination can be made according to first principles. An alternative apparatus and method uses spectroscopy without the density detector. | 2015-07-16 |
20150198539 | APPARATUS FOR INSPECTING EDGE OF SUBSTRATE - An apparatus for inspecting an edge portion of a substrate can inspect a defect or a chamfered width on an edge portion of a substrate. First and second right-angled prisms are disposed above and below the edge portion such that inclined surfaces thereof are directed toward the upper surface and lower surface of the edge portion. A lighting part irradiates the edge portion of the substrate with light. A photographing part is disposed adjacent to the edge portion. The photographing part takes an image of the upper surface of the edge portion from light that has passed through the first right-angled prism, an image of the lower surface of the edge portion from light that has passed through the second right-angled prism, and an image of an end surface of the edge portion. | 2015-07-16 |
20150198540 | DRY REAGENT BASED WATER ANALYZER - The invention provides devices, methods, and compositions for dry chemical reagents to measure calcium, magnesium (total hardness), and other analytes in water using colorimetric devices. The measurement may be a one-step procedure without the need of dilution and multi-step preparation, so that it can be easily employed by untrained personnel. The chemical reagents may include dyes, buffer reagents, masking reagents, competing ligands, and other chemicals such as fillers. The chemical reagents may be grinded together as a homogenous fine powder, equally dispensed into small containers for each test or dried as film or solid using the means of air, low heat or vacuum. The composition may be easily dissolved into water samples and stable for long term storage. The methods may be able to distinguish between similar materials such as magnesium and calcium with the same one reagent or from other interfering species in water samples | 2015-07-16 |
20150198541 | Method and device for examining a mask - A method for examining a mask includes providing a position data set having error positions of the mask to be examined, providing a structure data set having the structure of the mask, and specifying structural features of the mask, the values of which are to be determined. At each error position, determining the values of the specified structural features of the structure by using a computing unit, determining a measuring task from specified decision criteria and from the determined values of the structural features of the structure by using the computing unit, and carrying out the determined measuring task in a manner controlled by the computing unit. In addition, a device, in particular a microscope, for carrying out the method is provided. | 2015-07-16 |
20150198542 | INNER IMAGE GENERATING APPARATUS AND METHOD THEREOF - An inner image generating apparatus includes a first receiver configured to receive an inlet track information and a first passage time of a muon, a second receiver configured to receive an outlet track information and a second passage time of the muon, a displacement calculator configured to calculate a track displacement of a track of the muon based on the inlet and outlet track information, a mean energy calculator configured to calculate a mean energy of the muon based on a time-difference between the first passage and the second passage time, a data integration circuit configured to integrate multiplied data multiplying the track displacement and the mean energy on a projected plane, and an image generating circuit configured to generate an inner image of the structure by identifying a position of matter at the projected plane based on an integrated multiplied data. | 2015-07-16 |
20150198543 | SYSTEMS, DEVICES AND METHODS RELATED TO CALIBRATION OF A PROTON COMPUTED TOMOGRAPHY SCANNER - Disclosed are systems, devices and methodologies related to calibration of an ion based imaging apparatus such as a proton computed tomography scanner. In some implementations, energy degrader plates having known water-equivalent thickness (WET) values can be introduced to an ion beam to introduce different energy degradation settings. Energy detector responses to individual ions subject to such energy degradation settings can be obtained. Such responses can be normalized and correlated to water-equivalent path lengths (WEPL) of the ions based on the known WET values. Such calibration utilizing degrader plates can be performed relatively quickly and can yield accurate WEPL values that facilitate estimation of, for example, a CT image based on relative stopping power of an object. | 2015-07-16 |
20150198544 | SYSTEMS FOR DETERMINING AND IMAGING WAX DEPOSITION AND SIMULTANEOUS CORROSION AND WAX DEPOSIT DETERMINATION IN PIPELINES - The systems for determining and imaging wax deposition and simultaneous corrosion and wax deposit determination in pipelines relate to systems for determining wax deposition and corrosion by one or both of two techniques. In both techniques, a source of neutron radiation is directed at the pipeline. In one technique, a neutron detector surrounded by an absorption shield defining a collimation window counts neutrons reflected back to the detector by back diffusion or backscatter radiation. In the other technique, a gamma ray detector measures gamma rays emitted when the emitted neutrons are absorbed in the pipeline. A neutron moderator-reflector is placed around three sides of the pipeline to increase the likelihood of neutron capture. | 2015-07-16 |
20150198545 | HIGH TEMPERATURE SIMULATED DISTILLATION - Systems and methods for determining a boiling point distribution of a sample include controlling the rates of temperature increase for a column and an injection port. An analyzer includes a column having a column heating element and an injection port having an injection port heating element. The temperature of the column can be increased at a first rate, and a temperature of the injection port can be increased at a second rate. The first and second rates are selected such that the temperature of the injection port is within about five to fifteen degrees Celsius of the temperature of the column when the temperature of the injection port reaches a target temperature of minimal thermal decomposition. | 2015-07-16 |
20150198546 | STEAM QUALITY METER - A real time and online apparatus and methods measuring steam quality of a moving steam sample stream by superheating or cooling to subsaturated water using a known amount of heat and mass. The meter allows for continuous flow and can be used for verification and calibration of other steam quality measurement device. | 2015-07-16 |
20150198547 | SYSTEM AND METHOD FOR DETECTING A DEFECTIVE SAMPLE - In various embodiments, a system for detecting a defective sample may be provided. The system may include a chamber. The system may further include a pressure reducing mechanism coupled with the chamber. The system may additionally include a detector. The pressure reducing mechanism may be configured to reduce a pressure in the chamber. The detector may be configured to detect information indicating a temperature of the sample. Various embodiments may be capable of detecting water ingress or fluid ingress into the micro cracks or along the designed discontinuities, like bolts and rivets. | 2015-07-16 |
20150198548 | MEASURING INSTRUMENT FOR DETECTION OF ELECTRICAL PROPERTIES IN A LIQUID - A measuring instrument for detection of electrical properties in a liquid includes a main body configured to hold a tester, a first pole extending from the main body, and a second pole extending from the main body that is spaced apart from the first pole. The first pole carries a positive probe for attachment to the tester, and the second pole carries a negative probe for attachment to the tester. When the probes are placed in the liquid, electrical properties in the liquid are detected by the tester. | 2015-07-16 |
20150198549 | REACTOR FOAM SENSOR SYSTEMS AND METHODS OF USE - A foam sensor system includes a flexible bag comprised of a polymeric material and bounding a compartment. A foam sensor assembly is mounted on the flexible bag and includes a foam contact disposed within the compartment of the flexible bag. A ground assembly is mounted on the flexible bag and includes a ground contact disposed within the compartment of the flexible bag, the foam sensor assembly and the ground assembly being configured so that an electrical potential can be applied between the foam contact and the ground contact. | 2015-07-16 |
20150198550 | HF ALKYLATION PROCESS - An HF olefin/isoparaffin alkylation process is carried out in an alkylation unit with a settling vessel in which the alkylate product is separated from the HF acid catalyst containing water and acid soluble oil (ASO). The density of the liquids in the settling vessel is measured at different levels by means of a nuclear density profile analyzer. The acid strength of the acid phase is determined from the density measurement and an optional temperature measurement. The proportion of water in the acid phase may also be measured separately by measurement of its electrical conductivity to determine the respective contributions of the water and the ASO to the density of the HF acid phase. | 2015-07-16 |
20150198551 | GAS SENSOR PACKAGE - Provided is a gas sensor package, including: a gas sensing element; and a substrate on which the gas sensing element is disposed, in which a through hole corresponding to the gas sensing element is formed. | 2015-07-16 |
20150198552 | NOVEL CHEMISTRY USED IN BIOSENSORS - The invention relates to novel compositions and methods for the detection of analytes using the nuclear reorganization energy, λ, of an electron transfer process. | 2015-07-16 |
20150198553 | DEVICE FOR PROVIDING A MEANS FOR INTERNAL CALIBRATION IN AN ELECTROCHEMICAL SENSOR - Internally calibrated pH and other analyte sensors based on redox agents provide more accurate results when the redox active reference agent is in a constant chemical environment, yet separated from the solution being analyzed in such a way as to maintain electrical contact with the sample. Room temperature ionic liquids (RTIL) can be used to achieve these results when used as a salt bridge between the reference material and the sample being analyzed. The RTIL provides the constant chemical environment and ionic strength for the redox active material (RAM) and provides an electrolytic layer that limits or eliminates direct chemical interaction with the sample. A broad range of RAMs can be employed in a variety of configurations in such “Analyte Insensitive Electrode” devices. | 2015-07-16 |
20150198554 | DISPOSABLE TEST SENSOR - The present invention relates to disposable test sensors having improved sample application and measuring properties and their uses for detection, preferably, quantitative measurement, of analyte in a liquid sample like blood. In particular, the invention provides for an electrochemical biosensor which has a thin-layer fluid chamber having funnel-like shape with a novel extra wide opening as sampling entrance and a vent opening at the tip of the chamber for air escape. The thin-layer fluid chamber provides a reservoir from which a sample fluid can be drawn into it through capillary action. The extra wide sampling entrance provided by the present invention can draw blood into the chamber through any part of the opening, thus it allows easy targeting the samples with small volume, picking up smeared samples and it is more tolerant to users who jam the tip of the sensor into users' finger. | 2015-07-16 |
20150198555 | SAMPLE RECOGNITION METHOD AND BIOSENSOR USING SAME - A biosensor and a method for recognizing a liquid sample are provided, which can recognize whether a sample is introduced by recognizing an inside of a sample introduction channel through measurement of capacitance. The biosensor includes an upper plate and a lower plate facing each other, a middle plate interposed between the upper plate and the lower plate to form a sample introduction channel through a recess portion, a working electrode and an auxiliary electrode formed in the sample introduction channel, a sample recognition electrode formed on an outside of the sample introduction channel in a position that corresponds to the sample introduction channel, and a capacitance measurement portion electrically connected to any one of the working electrode and the auxiliary electrode and the sample recognition electrode. | 2015-07-16 |
20150198556 | SENSING ELECTRODE OF ENZYME-BASED SENSOR AND METHOD FOR MANUFACTURING THE SAME - The present invention relates to a sensing electrode of an enzyme-based sensor, and the enzyme-based sensor comprising the same can be stably stored at room temperature. The sensing electrode comprises: an electrode substrate and an enzyme sensing layer formed thereon, wherein the enzyme sensing layer comprises sequentially laminated layers of: a first carbon material-nano metal layer containing a carbon material and nano-metal particles; an ionic liquid layer comprising an ionic liquid consisting of a cation and an anion; a second carbon material-nano metal layer containing a carbon material and nano-metal particles; and an enzyme layer. The present invention also provides a method for manufacturing the sensing electrode of an enzyme-based sensor. | 2015-07-16 |
20150198557 | THREE-DIMENSIONAL METAL ION SENSOR ARRAYS ON PRINTED CIRCUIT BOARDS - An electronic device includes a substrate and a plurality of sensors. Each sensor is disposed in a well over the substrate and includes a working electrode, an inner filling solution disposed thereover, and an ion-selective membrane. The working electrode is in contact with the substrate and the ion-selective membrane is disposed over the inner filling solution and substantially seals the well. | 2015-07-16 |
20150198558 | Broadband Lambda Probe and Production Method for a Broadband Lambda Probe - A broadband lambda probe includes a measurement hollow space. The broadband lambda probe further includes an oxygen pump cell having an outer pump electrode and an inner pump electrode to enable the transfer of oxygen from the measurement hollow space to an external environment of the broadband lambda probe. The broadband lambda probe further includes a Nernst concentration cell. The broadband lambda probe further includes at least one capacitive sensor device. The at least one capacitive sensor device has a capacitance configured to be varied with a change of a concentration of at least one substance. The concentration is present in the respective at least one capacitive sensor device. The at least one capacitive sensor device is positioned in the broadband lambda probe to at least one of directly adjoin the measurement hollow space and partially project into the measurement hollow space. | 2015-07-16 |
20150198559 | FUNCTIONALIZED NANOPIPETTE BIOSENSOR - Disclosed are methods and devices for biomolecular detection, comprising a nanopipette, exemplified as a hollow inert, non-biological structure with a conical tip opening of nanoscale dimensions, suitable for holding an electrolyte solution which may contain an analyte such as a protein biomolecule to be detected as it is passed through the tip opening. Biomolecules are detected by specific reaction with peptide ligands chemically immobilized in the vicinity of the tip. Analytes which bind to the ligands cause a detectable change in ionic current. A sensitive detection circuit, using a feedback amplifier circuit, and alternating voltages is further disclosed. Detection of IL-10 at a concentration of 4 ng/ml is also disclosed, as is detection of VEGF. | 2015-07-16 |
20150198560 | ELECTROPHORETIC ANALYZER BY ELECTROMAGNETIC INDUCTION - Electrophoretic analyzer by electromagnetic induction, comprising a ferromagnetic toroidal core ( | 2015-07-16 |
20150198561 | MAGNETIC SENSOR DEVICE - Provided is a magnetic sensor device that is capable of relaxing a sensitivity change due to the position of a sample to be inspected, even with a configuration wherein the sample to be inspected is disposed on the side of an exciting coil and a detecting coil. Specifically, in a magnetic sensor device, an exciting coil and a detecting coil are disposed with respect to a sample disposing space, and the detecting coil detects an alternating current magnetic field generated by the exciting coil. As the exciting coil, this magnetic sensor device is provided with a first exciting coil, which is disposed on one side of the sample disposing space, and a second exciting coil, which is disposed on the other side of the sample disposing space. As the detecting coil, this magnetic sensor device is provided with a first detecting coil, which detects, on the other side of the sample disposing space, an alternating current magnetic field of the first exciting coil, and a second detecting coil, which detects, on the one side of the sample disposing space, an alternating current magnetic field of the second exciting coil. | 2015-07-16 |
20150198562 | PIEZOELECTRIC UNIT, PIEZOELECTRIC DEVICE, PIEZOELECTRIC DETERMINATION APPARATUS, AND STATE DETERMINATION METHOD - A piezoelectric unit | 2015-07-16 |
20150198563 | METHOD AND A DEVICE FOR IDENTIFYING MATERIAL TYPES OF SPATIAL OBJECTS - The present invention relates to a method for identifying material types of spatial objects characterized in that the method comprising obtaining an acoustic signal from each identified object by deforming the objects mechanically, recording said acoustic signal and comparing it to an acoustic model being obtained on the basis of analysis of reference objects of multiple material types. The present invention also relates to a device for identifying material types of spatial objects, comprising a deformation chamber (K), a mechanical deformation system (F), at least one electro-acoustic transducer ( | 2015-07-16 |
20150198564 | ULTRASONIC DEVICE, ULTRASONIC TRANSDUCER DEVICE, ELECTRONIC DEVICE AND ULTRASONIC IMAGING DEVICE - An ultrasonic device which includes a substrate, a first ultrasonic transducer element and a second ultrasonic transducer element. The substrate is provided with a plurality of first openings and a second opening having a larger opening area than the first opening. The first ultrasonic transducer element is provided on a first vibration film which has a first area and closes the first openings for each first opening, and includes two electrodes with a piezoelectric body being interposed therebetween. The second ultrasonic transducer element is provided on a second vibration film which has a second area larger than the first area and closes the second opening, and includes two electrodes with a piezoelectric body being interposed therebetween. The first openings are disposed in an array form. The second opening is disposed between an outer periphery of the substrate and regions where the first opening parts are disposed in an array form. | 2015-07-16 |
20150198565 | METHOD OF CHARACTERIZING AN OBJECT INCLUDING, AT LEAST LOCALLY, A PLANE OF SYMMETRY - A method of characterizing an object that includes, at least locally, a plane of symmetry, the method including performing at least one observation of ultrasound transmitted through the object, each observation being performed on an axis perpendicular to the plane of symmetry, each observation resulting from an emission of ultrasound generated along a respective one of the axes and meeting the object along the axis at an angle of incidence other than normal, the ultrasound meeting the object to follow a path that is symmetrical relative to the plane of symmetry. | 2015-07-16 |
20150198566 | ULTRASOUND DIAGNOSTIC APPARATUS, ULTRASOUND IMAGE GENERATION METHOD, AND RECORDING MEDIUM - The ultrasound diagnostic apparatus acquires an ultrasound image for examining an inspection object using an ultrasonic beam, and includes a sound velocity determiner configured to determine a sound velocity in the inspection object, and a sound velocity searching range setting section configured to set a range in which a sound velocity is searched by the sound velocity determiner. The sound velocity searching range setting section sets a sound velocity searching range using a sound velocity calculated in a predetermined range with respect to at least one of space and time. | 2015-07-16 |
20150198567 | ADAPTER HOUSING AND CONNECTING DEVICE FOR CHROMATOGRAPHY - An adapter housing is described that can be used for high performance liquid chromatography, which can be releasably connected to a socket unit. The adapter housing includes a bore which passes through the adapter housing and a pre-column which can be arranged in the bore to protect the separation column from contaminants and/or to concentrate the fluid to be analyzed. A sealing element seals the adapter housing in relation to the socket unit at the end-face wall of a pilot bore. | 2015-07-16 |
20150198568 | CHROMATOGRAPHY COLUMN FRAME AND METHOD OF CONDUCTING MAINTENANCE ON AND PACKING OF A CHROMATOGRAPHY COLUMN - A chromatography column frame comprising at least two legs, a support arrangement connected to said at least two legs, and a holder connected to said support arrangement. Said holder is arranged to releasably hold an adaptor rod of a chromatography column, so that the adaptor rod is prevented to move in a horizontal direction and so the adaptor rod is allowed to move in a vertical direction. | 2015-07-16 |
20150198569 | MASS ANALYSIS METHOD AND MASS ANALYSIS SYSTEM - Provided is a mass analysis method that prevents quantitative precision from decreasing. This mass analysis method uses an analysis system including a mass analysis device and a subdetector connected to each other, the subdetector displaying intensity and detection time relating to constituents of a sample at a preceding stage of the mass analysis device, the method comprising: (a) after injection of a sample, analyzing the sample with an analyzing apparatus including the subdetector, and after the sample has passed through the subdetector, injecting the sample into the mass analysis device; (b) acquiring data from both the subdetector and the mass analysis device; and (c) determining which of peaks that the subdetector and the mass analysis device have detected is to be analyzed, based on whether overlapping peaks are present and whether the same peak between data from the subdetector and the mass analysis device is present. | 2015-07-16 |
20150198570 | MASS-SPECTROMETER SYSTEMS AND METHODS - Embodiments of the present disclosure present novel systems, devices and methods for an automated biological sample analysis using mass-spectrometry. The time from sample introduction to the reporting of data, in some embodiments, takes a relatively short amount of time (e.g., several minutes). In some embodiments, a biological sample to be analyzed is a blood sample. For many applications, only a single drop of blood may be sufficient. Through the use of a mixture of standards with unique molecular mass, a quantitative analysis of the target analyte can be performed in a single MS run (for example), eliminating the need to create and analyze standard curves. One advantage of such embodiments may be that the system, devices, and methods can eliminate the need for batch creation since the requirement to amortize the time and effort of creating and analyzing standard curves can be eliminated. | 2015-07-16 |
20150198571 | INTEGRATED SYSTEM FOR LIQUID SEPARATION AND ELECTROSPRAY IONIZATION - The present invention relates to an integrated system for liquid separation, such as LC, CE, affinity chromatography, and ion exchange chromatography. A preferred aspect relates to a specialised protection means for protecting the fragile electrospray needle when not in use. Another preferred aspect relates to a specialised electrical contact means for applying voltage to the electrospray needle. The invention comprises an integrated system for liquid separation and electrospray ionization comprising: a separation column; and an electrospray emitter connected with the separation column. In one aspect there is a retractable protective sleeve ( | 2015-07-16 |
20150198572 | CHROMATOGRAPHIC SYSTEM AND METHOD OF ISOLATING COMPOUND IN SAMPLE USING CHROMATOGRAPHIC SYSTEM - A method is provided for isolating a compound in a sample by chromatography. The method includes determining an analytical gradient of an analytical system; performing an analytical run using the analytical gradient; identifying a target compound in the sample and determining an analytical retention time of the target compound using chromatographic results of the analytical run; determining an elution point of the target compound using the analytical retention time, the analytical gradient and characteristics of the analytical system; determining automatically a focusing gradient of a preparative system, including a slope segment; and performing a preparative run using the focusing gradient to separate the target compound from the sample. The slope segment includes a slope determining a concentration of solvent in a solvent mixture, which linearly increases from a first offset below the elution point of the target compound to a second offset above the elution point of the target compound. | 2015-07-16 |
20150198573 | METHOD AND SYSTEM FOR LIQUID CHROMATOGRAPHY DATA ANALYSIS - One embodiment of the invention is directed to a method of analyzing liquid chromatography data. The method comprises collecting, by a data processing system, first volume fractions data from a first liquid chromatography column for a first absorbance wavelength of light λ | 2015-07-16 |
20150198574 | AUTOMATED MICROEXTRACTION TECHNIQUE FOR THE ANALYSIS OF N-NITROSOAMINES IN WATER - An automated headspace solid-phase microextraction coupled with gas chromatography-mass spectrometry for the determination of four N-nitrosoamines in groundwater samples is developed. Response surface methodology technique was employed to investigate the optimized extraction conditions of headspace solid-phase microextraction using CombiPAL autosampler. The method was applied to determine the N-nitrosamine concentrations in groundwater samples. | 2015-07-16 |
20150198575 | METHOD AND KIT FOR DETERMINING IF A SHOCK TREATMENT IS NECESSARY FOR A WATER SOURCE - A kit for determining if a shock treatment is required for a water source may comprise a test strip having at least two chemically treated test areas. One of the areas is responsive in color to a concentration of free chlorine in the water and another test area is responsive in color to a concentration of total chlorine in the water. A chlorine indicator scale may be provided on a substrate, such as a label, and comprises a plurality of pairs of colored indicia and each pair of colored indicia representing a color pattern indicating a concentration, or range of concentrations, of total chlorine and free chlorine in the water. An alphanumeric designation may be provided adjacent to each pair of indicia indicating whether a shock treatment is required for the water source based on a color pattern the associated indicia pattern. | 2015-07-16 |
20150198576 | Composition for the Calorimetric Detection of Water in Hydrocarbon Fuels and a Process for the Preparation Thereof - The embodiments of the present invention disclose a composition for the colorimetric detection of water in hydrocarbon fuels and a process for the preparation thereof. The embodiments of the present invention relate to an improved method for determining the presence or absence of water in non-polar organic fluids such as petroleum oil or hydrocarbon oils by using an indicator system containing a water insoluble wetting agent and a water soluble dye which can be performed rapidly without costly instrumentation and tedious, time consuming analytical methods. | 2015-07-16 |
20150198577 | Boron And Lithium Isotopic Method For Tracing Hydrocarbons And Their By-Products - The invention relates to methods for determining the source of hydrocarbons presented in the pores of a host rock or found in contaminated groundwater. The method includes the steps of (a) determining a first isotopic composition of boron and/or lithium in one or more components within a potential source rock sample, such as kerogen, clay, or water; (b) determining a second isotopic composition of boron and/or lithium in the hydrocarbons found within the pores of a host rock sample or in contaminated groundwater; and (c) comparing the first and second isotopic compositions to determine whether the potential source rock is the source of the hydrocarbons within the pores of the host rock or in contaminated groundwater. The comparison is facilitated by using the isotope fractionation between the kerogen, clay, or water components and the bitumen component of the potential source rock, which allows one to predict the isotope composition of any hydrocarbons originating in the bitumen component of the source rock, based on the isotope composition of one of the other three phases. The method can be used to select host rock for extracting oil and other hydrocarbons, as well as in remediating groundwater contamination. | 2015-07-16 |
20150198578 | WIRELESS SYSTEM AND METHOD FOR MEASURING AN OPERATIVE CONDITION OF A MACHINE - System including a sensor configured to be disposed within a reservoir of a machine having moving parts that are lubricated by a liquid in the reservoir. The sensor is configured to obtain a measurement of the liquid that is representative of at least one of a quantity or quality of the liquid in the reservoir. The system also includes a device body operably coupled to the sensor. The device body has a processing unit that is operably coupled to the sensor and configured to generate first data signals representative of the measurement of the liquid. The device body also includes a transmitter that is configured to wirelessly communicate the first data signals to a remote reader. | 2015-07-16 |
20150198579 | DATA PROCESSING DEVICE AND AUTOMATIC ANALYSIS DEVICE USING SAME - An automatic analysis device includes: a factor storage unit | 2015-07-16 |
20150198580 | COVERSLIP AND METHODS FOR REMOVING - The invention provides a coverslip for automated decoverslipping of a tissue bearing slide comprising a horizontal base portion having a length, width, and height, at least two side wall portions extending downward from opposite sides of the base portion each having a length and width and h; and wherein the total wall volume to base volume ratio is greater than or equal to approximately 0.025. | 2015-07-16 |
20150198581 | METHOD, MOBILE APPLICATION, AND SYSTEM FOR PROVIDING FOOD SAFETY MAP - A method for providing food safety map comprises: immersing a reagent block of a food safety testing sheet into a specimen; using camera of a mobile device to take a picture of the reagent block to obtain a reactive image; analyzing the reactive image to obtain a food safety information; obtaining an address information according to the location; transmitting the food safety information and the address information to a server through a wireless connection; using that server to map the food safety information to a map according to the address information; and publishing the map to the Internet. | 2015-07-16 |
20150198582 | DIAGNOSTIC METHOD OF CARDIOVASCULAR DISEASE - Biological metabolites LysoPC (18:0), LysoPC (20:3), fatty acid (16:1), fatty acid (18:0), fatty acid (18:1), fatty acid (18:2) and fatty acid (22:6) according to the present disclosure allow for simple and accurate diagnosis of a cardiovascular disease since their level in the blood of a subject increases or decreases if the subject has a cardiovascular disease such as myocardial infarction or angina. In addition, whereas the existing biomarkers can diagnose only whether myocardial infarction occurs or not, the biological metabolites according to the present disclosure can diagnose not only myocardial infarction but also unstable angina occurring prior to the onset of myocardial infarction stage by stage. | 2015-07-16 |
20150198583 | METHOD OF BIOMARKER VALIDATION AND TARGET DISCOVER - Disclosed herein are methods of discovering and validating select endophenotypes encompassing tumorigenic cancer stem cells. | 2015-07-16 |
20150198584 | IDENTIFICATION OF FUNCTIONAL CELL STATES - Embodiments herein described provide methods for determining phenotypic parameters of cell populations and expressing them in terms of tensors that can be compared with one another. Embodiments provide methods for determining phenotypic parameters of cell populations in response to an agent. Embodiments provide methods for comparing effects of an agent on phenotypic parameters to effects of reference standards whose in vivo effects are known. Embodiments provide methods for predicting the effect of an agent by the comparison with the known effects of reference standards. Embodiments provide methods for classifying agents by their effects on phenotypic parameters. Embodiments provide software and computer systems for calculating multiparametric tensors, compressing their complexity and comparing them after compression. | 2015-07-16 |
20150198585 | METHODS, COMPOSITIONS AND KITS FOR ASSAYING MITOCHONDRIAL FUNCTION - The invention provides methods, compositions, devices, and kits relating to the use of cholesterol-dependent cytolysins (e.g., PFOs) for measuring intracellular mitochondrial activity. | 2015-07-16 |
20150198586 | DEVICES AND METHODS FOR ENHANCED DETECTION AND IDENTIFICATION OF DISEASES - Disclosed are micro-devices and methods of using the same for detecting at the microscopic level a property of a biological material contained in a liquid or existing in a liquid state. The device comprises an inlet ( | 2015-07-16 |
20150198587 | Detecting Cells in a Cell Suspension - The embodiments relate to an arrangement for quantifying cells. The arrangement includes a magnetic field-sensitive sensor having a first and second pair of sensor elements. The sensor elements of the first pair are connected as part of a Wheatstone bridge and have a first spacing of between half and double a first average size of a first cell or cell conglomerate type. The sensor elements of the second pair are connected as part of a Wheatstone bridge and have a second spacing of between half and double a second average size of a second cell or cell conglomerate type. A third spacing of the two closest sensor elements of the pairs is greater than the larger of the two average sizes. The arrangement also includes a channel for conducting the cell suspension past the sensor elements. | 2015-07-16 |
20150198588 | MODULAR POINT-OF-CARE DEVICES, SYSTEMS, AND USES THEREOF - The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications. | 2015-07-16 |
20150198589 | USE OF EDTA TUBE WITH GEL IN ELISA METHOD - The invention relates to elimination of the false negative or defective results obtained as a result of inadequate or no sample collection by the test sampling probes in the analyzers running with full or semi-automatic Elisa method in the studies conducted from the serum today in determination of the anti HIV, anti HCV, Syphilis antibodies and HBSAg antigen by employing ELISA (Enzyme Linked Immune Sorbent Assay) method, one of the serologic methods, in full or semi-automatic analyzers by use of the plasma obtained from EDTA gel tube. | 2015-07-16 |
20150198590 | TROPOMYOSIN ISOFORMS RELATED TO ALZHEIMERS DISEASE AND MILD COGNITIVE IMPAIRMENT - The present invention provides an in vitro method to aid the diagnosis of Alzheimer's disease (AD) or Mild Cognitive Impairment (MCI), comprising determining the level of expression of one or more tropomyosin isoform(s) corresponding to P09493-3 and/or P09493-1 in a patient's sample. A kit comprising probes that bind to tropomyosin isoforms P09493-3 and P09493-1 is also provided | 2015-07-16 |
20150198591 | METHODS FOR DETECTING AND MEASURING AGGREGATION - Methods, compositions, systems, and devices are provided for performing and analyzing agglutination assays. In one aspect, methods for image analysis of agglutination assays are provided. In another aspects, methods for performing agglutination assays are provided. In one aspect, the methods may be used for the detection of various molecules, including viruses or antibodies against a virus. In another aspect, the methods can be used to determine effective immunization of a subject. | 2015-07-16 |
20150198592 | Rapid Lateral Flow Assay Method for Low Quantity Liquid or Dry Samples - This invention describes a device for assaying a dry or small volume liquid sample on a lateral flow capillary assay by utilizing a supplementary aqueous solution that will push the sample up the assay without diluting or significantly diluting the original sample. This invention enables a sample to be assayed rapidly and/or on-site when the sample is in dried or solid form, or when the liquid volume is too small to complete an assay. As an option, the device can display a colored signal when a sufficient amount of liquid sample has been collected or added to the device. The minimal liquid volume requirement of the device significantly reduces the sample collection time to a matter of seconds and resolves situations in which fluids available for collection are not abundant. Therefore, this invention allows the lateral flow test device to be a more rapid, efficient, and versatile apparatus. | 2015-07-16 |
20150198593 | METHOD AND SYSTEM OF MICROFLUIDIC IMMUNOASSAY USING MAGNETIC BEADS - A microfluidic Western blot method and system including a microfluidic western blot method for immunoassay of proteins, the method including introducing a sample including the proteins onto a chip; electrophoretically separating the proteins; binding the separated proteins to beads to form protein-attached beads, the beads being magnetic; flowing the protein-attached beads into a magnetic holding region; applying a magnetic field to the magnetic holding region to fix the protein-attached beads in place within the magnetic holding region; binding primary antibodies to target proteins on the protein-attached beads; binding secondary antibodies to the bound primary antibodies; and detecting the bound secondary antibodies. | 2015-07-16 |
20150198594 | TEST CARTRIDGE FOR USE IN RAPID ANALYSIS OF BIOLOGICAL SAMPLES - A test cartridge for use in sample analysis is provided. The test cartridge includes a reservoir card that further includes a reagent that includes living biological cells; and a test cartridge base configured to accept the reservoir card. The reservoir card is configured to interface with a test cartridge base through at least one fluid port. The test cartridge base includes an elliptical reaction chamber having a central axis and an inlet channel connected to the reaction chamber. The inlet channel is positioned above the reaction chamber at an angle of 15-60 degrees above the horizontal and is offset from the central axis of the reaction chamber. Upon introducing a sample to be analyzed into the test cartridge base through the inlet channel, the sample is homogeneously mixed with the reagent while minimizing damage to the living biological cells. | 2015-07-16 |
20150198595 | A25 Bacteriophage Lysin - The invention relates to the identification, sequencing, and isolation of an A25 bacteriophage lysin gene that expresses a protein involved in the lysis of bacterial cells during the phage life cycle. The invention further relates to methods for lysing certain bacteria using lysin, which are useful for example in a diagnostic procedure designed to detect these bacteria. | 2015-07-16 |
20150198596 | Apparatus and Method for Detection of an Analyte in a Sample - There is provided mechanisms for the detection of an analyte in a sample. The mechanisms utilize at least a first measurement channel comprising a detection reactant corresponding to the analyte to be detected, and at least a microstructure associated with the first measurement channel. When the mechanisms are in use, the sample is introduced into the first measurement channel and propagated by way of the first measurement channel towards the microstructure. If the analyte is present in the sample, the analyte interacts with the detection reactant to form a networked product, and the microstructure is configured to filter the networked product. | 2015-07-16 |
20150198597 | Method for monitoring PARP activity in cells by PARP activation - The current invention provides for improved methods for determining PAR, and uses thereof. These improved methods involve an incubation step at a low temperature, for example around, but above, the freezing point after a PARP activation step. This improves the assay's sensitivity in comparison to current assay's performance. For example, sensitivity can be improved in methods assaying cells obtained from subjects such as human patients. The current invention also allows to provide methods to screen compounds for modulating PARG and/or PARP activity. | 2015-07-16 |
20150198598 | KIT FOR DIAGNOSING MALIGNANT MELANOMA - Provided is a kit for diagnosing at a high reproducibility, said kit being produced by preparing a monoclonal antibody against GPC3 and a monoclonal antibody against SPARC that are superior in quality stability to commercially available and commonly employed antibodies, and using these antibodies. | 2015-07-16 |
20150198599 | TLE3 AS A MARKER FOR CHEMOTHERAPY - Methods of using TLE3 as a marker for predicting the likelihood that a patient's cancer will respond to chemotherapy. Methods of using TLE3 as a marker for selecting a chemotherapy for a cancer. | 2015-07-16 |
20150198600 | Autoantibody Profiles in the Early Detection and Diagnosis of Cancer - The present invention provides methods, compositions and kits for the detection of cancer diagnostic biomarkers, for the diagnosis of cancer, for the identification of a subject at risk for developing cancer, and for the generation of patient-specific cancer diagnostic biomarker profiles. | 2015-07-16 |