28th week of 2017 patent applcation highlights part 18 |
Patent application number | Title | Published |
20170197864 | CONTINUOUS PROCESSING OF FLEXIBLE GLASS RIBBON - A method of continuously processing glass ribbon having a thickness<0.3 mm. The method includes providing a glass processing apparatus having a first processing zone, a second processing zone and a third processing zone. The glass ribbon is continuously fed from the first processing zone, through the second processing zone to the third processing zone. The feed rate of the glass ribbon is controlled through each processing zone using a global control device. A first buffer zone is provided between the first processing zone and the second processing zone in which the glass substrate is supported in a first catenary between two, spaced-apart, payoff positions. A second buffer zone is provided between the second processing zone and the third processing zone in which the glass substrate is supported in a second catenary between two, spaced-apart, payoff positions. | 2017-07-13 |
20170197865 | MOLD, METHOD FOR PRODUCING A MOLD, AND METHOD FOR FORMING A MOLD ARTICLE - Various embodiments provide a mold including a pyrolytic carbon film disposed at a surface of the mold. Various embodiments relate to using a low pressure chemical vapor deposition process (LPCVD) or using a physical vapor deposition (PVD) process in order to form a pyrolytic carbon film at a surface of a mold. | 2017-07-13 |
20170197866 | Method of processing a panel of multilayer tempered glass and article obtained by said method - Method of processing a panel of multilayer tempered glass comprising the steps of:
| 2017-07-13 |
20170197867 | HERMETIC SEALING METHOD AND HERMETIC-SEALED SUBSTRATE PACKAGE - The present invention relates to a hermetic sealing method and a hermetic-sealed substrate package and, more specifically, to a hermetic sealing method for hermetically sealing the space between two substrates by a glass frit paste, and a substrate package manufactured thereby. To this end, the present invention provides a hermetic sealing method comprising: a substrate preparation step for preparing a first substrate and a second substrate smaller than the first substrate; a glass frit paste applying step for applying the glass frit paste such that the glass frit paste adheres to the upper periphery of the first substrate and a side of the second substrate while the first and second substrates are disposed to face each other; and a laser irradiation step for irradiating a laser beam to the applied glass frit paste to hermetically seal the space between the first and second substrates. | 2017-07-13 |
20170197868 | Laser Processing of Electronic Device Structures - Laser processing techniques may be used to form structures for electronic devices. A laser processing system may be provided with lasers and positioners for moving laser beams across a structure to be processed such as a layer of glass or other material. A laser such as a pulsed infrared laser may be move along a path across the layer of material. The laser may create a series of damaged regions along the path. A portion of the layer may be removed from other portions of the layer by breaking off the portion of the layer along the path. Laser-induced heating techniques and mechanical stress-inducing techniques may be used to impart stress to the layer of material to help break off the portion. The layer may include one or more sublayers such as layers of glass substrate material in a display. | 2017-07-13 |
20170197869 | CHEMICALLY STRENGTHENABLE LITHIUM ALUMINOSILICATE GLASSES WITH INHERENT DAMAGE RESISTANCE - A group of glass compositions in the Li | 2017-07-13 |
20170197870 | THIN THERMALLY AND CHEMICALLY STRENGTHENED GLASS-BASED ARTICLES - Embodiments of thermally and chemically strengthened glass-based articles are disclosed. In one or more embodiments, the glass-based articles may include a first surface and a second surface opposing the first surface defining a thickness (t), a first CS region comprising a concentration of a metal oxide that is both non-zero and varies along a portion of the thickness, and a second CS region being substantially free of the metal oxide of the first CS region, the second CS region extending from the first surface to a depth of compression of about 0.17·t or greater. In one or more embodiments, the first surface is flat to 100 μm total indicator run-out (TIR) along any 50 mm or less profile of the first surface. Methods of strengthening glass sheets are also disclosed, along with consumer electronic products, laminates and vehicles including the same are also disclosed. | 2017-07-13 |
20170197871 | FRIT MATERIAL, PHOTOELECTRIC PACKAGED DEVICE AND PACKAGING METHOD THEREOF, AND DISPLAY APPARATUS - Examples of the present invention provide a frit material, a photoelectric packaged device and a packaging method thereof, and a display apparatus. They relates to the field of display technology, and may reduce the bubbles generated during the sintering of the frit material at high temperature, improve the flatness of the surface of the frit material, and increase the proportion of the packaged area after the frit material is adhered to the device substrate, to increase the mechanical strength of the packaged OLED panel, while the viscosity of the frit material is not affected. The frit material comprises frit-powders and an organic material comprising an organic thickener, wherein the frit material further comprises an inorganic thickener consisting of a clay mineral material. Examples of the present invention are used for production of the frit material, the photoelectric packaged device comprising the frit material, and the display apparatus. | 2017-07-13 |
20170197872 | BIO-SOLUBLE INORGANIC FIBER - Inorganic fibers including the following composition, SiO | 2017-07-13 |
20170197873 | METHODS AND SYSTEMS RELATING TO ENHANCING MATERIAL TOUGHNESS - Natural materials often boast unusual combinations of stiffness, strength and toughness currently unmatched by today's engineering materials. Beneficially, according to the embodiments of the invention, these unusual combinations can be introduced into ceramics, glasses, and crystal materials, for example by the introduction of patterns of weaker interfaces with simple or intricate architectures. Two-dimensional surface modifications and three-dimensional arrays of effects within these materials allow for the deformation of these materials for increased flexure, impact resistance, etc. Further, the addition of interlocking substrate blocks in isolation or with additional flexible materials provide for improved energy dissipation and toughening. Such modified materials, based on carefully architectured interfaces, provide a new pathway to toughening hard and brittle materials. | 2017-07-13 |
20170197874 | DECORATIVE GLASS PANEL - The invention relates to an almost opaque decorative glass panel comprising a substrate made of a vitreous material bearing a multilayer stack including at least one light-absorbing functional layer and transparent dielectric coatings such that the light-absorbing functional layer is enclosed between dielectric coatings. The light-absorbing functional layer has a geometric thickness comprised between 25 and 140 nm, and an extinction coefficient k of at least 1.8. The multilayer stack in addition comprises at least one attenuating layer placed between the substrate and the light-absorbing functional layer, having a thickness comprised between 1 and 50 nm, having a refractive index n higher than 1 and an extinction coefficient k of at least 0.5. Furthermore, a transparent dielectric coating the optical thickness of which is comprised between 30 and 160 nm, and the refractive index n of which is higher than 1.5, is placed adjacent to the attenuating layer on the side opposite the light-absorbing functional layer. The invention provides a decorative panel offering a pleasant aesthetic effect. | 2017-07-13 |
20170197875 | GLASS SUBSTRATE WITH ANTIFOULING LAYER AND FRONT PLATE FOR DISPLAY - A glass substrate with an antifouling layer includes: a glass substrate which has a pair of principal surfaces facing to each other; a cohesive layer provided on the side of one principal surface of the glass substrate; and an antifouling layer provided on a surface of the cohesive layer, wherein the cohesive layer has a layer, the layer is in contact with the antifouling layer, contains mainly a silicon oxide, and contains carbon atoms at a concentration of 5×10 | 2017-07-13 |
20170197876 | ULTRA-THIN, NON-FRANGIBLE GLASS AND METHODS OF MAKING - Glasses having a thickness tin a range from about 0.1 mm to less than 0.4 mm which, when chemically strengthened, is non-frangible and has a physical center tension CT (also referred to herein as “physical CT”), wherein CT>|−1.956×10 | 2017-07-13 |
20170197877 | METHOD OF STRENGTHENING GLASS USING PLASMA TORCHES AND/OR ARC JETS, AND ARTICLES MADE ACCORDING TO THE SAME - Certain example embodiments relate to an improved method of strengthening glass substrates (e.g., soda lime silica glass substrates). In certain examples, a glass substrate may be chemically strengthened by creating an electric field within the glass. In certain cases, the chemical tempering may be performed by surrounding the substrate by a plasma including certain ions, such as Li | 2017-07-13 |
20170197878 | OPTICAL FIBER WITH REDUCING HYDROGEN SENSITIVITY - The present disclosure is directed to a method of making an optical fiber with improved bend performance, the optical fiber having a core and at least one cladding layer, and a chlorine content in the in the last layer of the at least one cladding layer that is greater than 500 ppm by weight. The fiber is prepared using a mixture of a carrier gas, a gaseous chlorine source material and a gaseous reducing agent during the sintering of the last or outermost layer of the at least one cladding layer. The inclusion of the reducing gas into a mixture of the carrier gas and gaseous chlorine material reduces oxygen-rich defects that results in at least a 20% reduction in TTP during hydrogen aging testing. | 2017-07-13 |
20170197879 | Asphalt Composition - The asphalt composition of the present invention is an asphalt composition comprising 1% to 15% by mass of a block copolymer (a) and an asphalt (c), wherein the block copolymer (a) comprises a specific block copolymer (a-1) and a specific block copolymer (a-2) in specific amounts, wherein the content of a vinyl aromatic monomer unit in the block copolymer (a) is 34% by mass or more and 55% by mass or less, the number average molecular weight of the block copolymer (a-1) is in the range of 20,000 to 73,000, and the number average molecular weight of the block copolymer (a-2) is 1.5 to 5.0 times higher than the number average molecular weight of the block copolymer (a-1). | 2017-07-13 |
20170197880 | Low water content plastic composition comprising hydraulic cement and method for manufacturing same - The present invention relates to a low water content plastic composition comprising hydraulic cement and a method for manufacturing the same. The present invention provides a low water content plastic composition comprising hydraulic cement and a method for manufacturing the same, the composition being characterized by losing flowability and having plasticity since from a flowable, uniform mixture state of hydraulic cement and water with polyol and isocyanate compounds which are raw materials for forming foamed polyurethane, part of the water used in the mixture is separated and removed due to foaming in the course of formation of the foamed polyurethane. | 2017-07-13 |
20170197881 | COBALT FREE PREPROMOTED UNSATURATED POLYESTER RESIN SYSTEM FOR ENGINEERED STONE - The invention relates to a formable composition for the preparation of engineered stone comprising a cobalt free prepromoted unsaturated polyester resin system, an inorganic particulate material and a peroxide component. The invention also relates to a method for the preparation of engineered stone as well as to the use of the cobalt free prepromoted unsaturated polyester resin system for the preparation of engineered stone. | 2017-07-13 |
20170197882 | COMPOSITION FOR JOINTS - A composition based on calcium carbonate includes nanometric boehmite and/or nanometric aluminium trihydroxide. A coating can be obtained from this composition. This composition makes it possible to obtain products having better high-temperature dimensional stability. | 2017-07-13 |
20170197883 | Dry Cement Mixture - A dry cement mixture comprises Portland cement and an ultra-fine component consisting of at least one ultra-fine additive, said ultra-fine component being a hydraulic binder, wherein Portland cement is present in an amount of at least 70 wt % of the mixture and the ultra-fine component is present in an amount of at least 5 wt % of the mixture, wherein the ultra-fine component has a particle size distribution characterized by a particle diameter D | 2017-07-13 |
20170197884 | HIGH STRENGTH, OPERATIONALLY ROBUST LOST CIRCULATION PREVENTATIVE PSEUDO-CROSSLINKED MATERIAL - A formulation for use as a lost circulation preventive material is a cement-forming aqueous fluid comprising water, at least one viscoelastic surfactant (VES), at least one monovalent or multivalent salt, at least one magnesium powder, and at least one retarder. The formulation is used in a method of drilling into a subterranean formation that includes introducing into a wellbore passing at least partially through the subterranean formation the cement-forming aqueous fluid, and further increasing the viscosity of the aqueous fluid by the action of the VES forming elongated micelles; where the at least one monovalent salt is present in an amount effective to pseudo-crosslink the elongated VES micelles to further increase the viscosity of the aqueous fluid. The formulation further forms a cement by reacting the at least one magnesium powder and the water which reaction is retarded by the retarder. The water may be saline water. | 2017-07-13 |
20170197885 | SINTERED COMPACT AND CUTTING TOOL - A sintered compact according to the present invention includes: a first material that is cubic boron nitride; a second material that is an oxide of zirconium; and a third material that is an oxide of aluminum, the second material including cubic ZrO | 2017-07-13 |
20170197886 | SINTERED COMPACT AND CUTTING TOOL - A sintered compact has a first material, a second material, and a third material. The first material is cubic boron nitride. The second material is a compound including zirconium. The third material is an aluminum oxide and the aluminum oxide includes a fine-particle aluminum oxide. The sintered compact has a first region in which not less than 5 volume % and not more than 50 volume % of the fine-particle aluminum oxide is dispersed in the second material. On arbitrary straight lines in the first region, an average value of continuous distances occupied by the fine-particle aluminum oxide is not more than 0.08 μm and a standard deviation of the continuous distances occupied by the fine-particle aluminum oxide is not more than 0.1 μm. | 2017-07-13 |
20170197887 | METHOD OF ANNEALING CERAMIC GLASS BY LASER - A method for annealing thin-films of ceramics such as Al | 2017-07-13 |
20170197888 | MASONRY TREATMENT COMPOSTITION - Provided is a masonry treatment composition containing a fluorine-containing polymer, which contains, as essential components, a fluorine-containing monomer having a fluoroalkyl group represented by the formula (a) CH | 2017-07-13 |
20170197889 | C FERTILIZER AND FEED PRODUCT - A compatible combination of micron size carbon based particles along with beneficial microbial species and conventional plant nutrients into a plant or an animal food. This balanced product is a combination of nutrients and microbes, and can be applied as a suspension in water or as a slow release granule. This combination of organic plant food and fertilizer can also be applied as a foliar, as a seed coating, and as an all-in-one granule combination of nutrients and biological agents, to facilitate mineralization, nutrient availability and provide energy to the soil and plants, with a total conversion of a storable processed biomass into a precisely known quality and quantity of usable fertilizer ‘tea’ solution, with no biomass waste, odors, or crop application timing problems. The process of formulating the combination product reduces green house gas emissions by limiting mineralization and composting | 2017-07-13 |
20170197890 | INCORPORATION OF BIOLOGICAL AGENTS IN FERTILIZERS - A biological-laden dry fertilizer includes a dry fertilizer granule and a coating inoculated with a biological agent and applied to the dry fertilizer granule. The biological coating is a solution or suspension comprising water or oil and at least one biological agent, or an emulsion of an oil and a solution or suspension comprising water and at least one biological agent. The at least one biological agent is a biological chemical, plant extract, microbial agent, and/or a living organism. | 2017-07-13 |
20170197891 | QUANTUM CARRIER FOR IMPROVING SOIL FUNCTION AND METHOD OF PREPARATION THEREOF - A quantum carrier for improvement of soil functions and method of preparation thereof, the method of preparation includes crushing the oyster shell before subjecting to a first high temperature sintering at the temperature of between 800 and 1300° C. for between 1.5 and 2.5 hour, followed by mixing with diatomaceous earth, soil and water to form a liquid oyster shell liquid for liquid sintering at a temperature of between 800 and 1300° C. for between 7 and 9 hours, to give a dimpled or honeycomb-like particle with rough surface, the quantum carrier; the quantum carrier obtained by said method has the function of soil improvement, soil improvement includes self-purification of the soil, degradation of the heavy metals and toxin residues in the contaminated soil, water content increase, oxygen content increase, protein content increase, pH adjustment, pest elimination and promotion of microbial growth. | 2017-07-13 |
20170197892 | ANTIFOULING OLIGOMERIZATION CATALYST SYSTEMS - According to one embodiment, a catalyst system that reduces polymeric fouling may comprise at least one titanate compound, at least one aluminum compound, and at least one antifouling agent or a derivative thereof. The antifouling agent may comprise a structure comprising a central aluminum molecule bound to an R1 group, bound to an R2 group, and bound to an R3 group. One or more of the chemical groups R1, R2, and R3 may be antifouling groups comprising the structure —O((CH | 2017-07-13 |
20170197893 | PROCESS FOR THE PREPARATION OF ETHYLENE GLYCOL FROM SUGARS - A process for the preparation of ethylene glycol comprising the steps of hydrogenating a composition comprising C | 2017-07-13 |
20170197894 | PROCESS FOR PRODUCTION OF METHANOL - The present application relates to a process comprising the steps of—providing a purge stream from a synthesis section,—preheating at least part of said purge stream,—adding steam to the preheated purge stream to obtain a first mixed stream,—passing the first mixed stream through a shift conversion step thereby obtaining a conversion product stream,—passing at least part of the conversion product stream through a H | 2017-07-13 |
20170197895 | PRODUCTION METHOD FOR GAMMA, DELTA-UNSATURATED ALCOHOLS - Provided is a method from which a γ,δ-unsaturated alcohol having a much more smaller amount of inclusion of formic acid and a formic acid ester and having a high purity can be obtained in a high yield. Specifically, provided is a method for producing a γ,δ-unsaturated alcohol by causing a reaction between an α-olefin and formaldehyde, the method including a step of bringing a reaction liquid obtained through the reaction into contact with an alkaline aqueous solution so as to provide an aqueous solution having pH of 9 to 13. | 2017-07-13 |
20170197896 | NOVEL POLYFLUOROALKYLATED ALKENES AND SILICON COMPOUNDS PREPARED THEREFROM - Novel polyfluoroalkylated alkenes and silane and silicon compounds prepared therefrom are described. | 2017-07-13 |
20170197897 | Skin Lightening Compounds - The present invention provides a compound of Formula I, II or III or a salt or prodrug derivative thereof that is a skin-lightening agent useful for the inhibition of melanin synthesis and/or the removal of existing melanin to function as a skin-lightening agent. | 2017-07-13 |
20170197898 | SYNTHESIS OF INTERMEDIATE FOR TREPROSTINIL PRODUCTION - The compound according to Formula I is an intermediate in the synthesis of prostacylin analogs. The present invention provides an efficient method for synthesizing a Formula I compound. | 2017-07-13 |
20170197899 | Method for Improving Preservation Stability of 2,2-Difluoroacetoaldehyde - A method for improving preservation stability of 2,2-difluoroacetaldehyde according to the present invention include at least: a first step of forming a “2,2-difluoroacetaldehyde-alcohol composite system” in which a 2,2-difluoroacetaldehyde hemiacetal coexists with an excess alcohol, wherein the total molar amount of the alcohol is 1.15 to 4.00 times the total molar amount of 2,2-difluoroacetaldehyde; and a second step of storing, in a storage container, the “2,2-difluoroacetaldehyde-alcohol composite system” formed in the first step. It is possible by this method to suppress the conversion of the 2,2-difluoroacetaldehyde hemiacetal to a dimer and maintain the original aldehyde activity of the target compound with less composition change over a long term. | 2017-07-13 |
20170197900 | HETEROGENEOUSLY CATALYZED CHEMICAL REDUCTION OF CARBON DIOXIDE - The presently disclosed and/or claimed inventive concept(s) relates generally to the reduction of carbon dioxide by heterogeneous catalysis. More particularly, but not by way of limitation, the presently disclosed and/or claimed inventive concept(s) relates to the reduction of carbon dioxide by heterogeneous catalysis with a heterogeneous hydrogenation catalyst comprising structurally frustrated Lewis pairs, wherein, for example but not by way of limitation, formic acid is produced and hydrocarbons are indirectly produced. In one non-limiting embodiment, the heterogeneous catalyst comprises hexagonal boron nitride (h-BN) having structurally frustrated Lewis pairs therein. | 2017-07-13 |
20170197901 | Method for Preparing Organic Vapor-Phase Dehydration Feedstock - The present invention relates to a method including: directly heating a fermentation broth to remove impurities, thereby preparing an organic vapor-phase dehydration feedstock; and continuously subjecting the organic vapor-phase dehydration feedstock to a vapor-phase dehydration reaction. According to the present invention, impurities in a fermentation broth, which have been removed by a multi-step process in the prior art, can be completely removed in a single-step process, and thus the time, cost and energy required for a process for preparing an organic vapor-phase dehydration feedstock from the fermentation broth can be effectively reduced, and the process for preparing the organic vapor-phase dehydration feedstock and a vapor-phase dehydration reaction can be continuously performed in an effective manner. | 2017-07-13 |
20170197902 | METHOD FOR PRODUCING MULTIBRANCHED ALIPHATIC ESTER - A method for producing a multibranched aliphatic ester including reacting a multibranched aliphatic alcohol with a multibranched aliphatic carboxylic acid in the absence of a solvent without a catalyst to obtain a multibranched aliphatic ester, and distilling the multibranched aliphatic ester to obtain a purified multibranched aliphatic ester, wherein at least one of the alcohol and the carboxylic acid is a C | 2017-07-13 |
20170197903 | CATIONIC LIPID - The present invention provides a technology which enables introduction of an active ingredient (e.g. nucleic acids) into various cells with a high efficiency, and compounds used therefor. The present invention provides a compound represented by the formula: | 2017-07-13 |
20170197904 | FLUORINATED CBD COMPOUNDS, COMPOSITIONS AND USES THEREOF - The present invention relates to fluorine substituted CBD compounds, compositions thereof and uses thereof for the preparation of medicaments. | 2017-07-13 |
20170197905 | METHOD FOR PRODUCING 2-HALOGEN-ACRYLIC ACID ESTERS - The present invention relates to a process for preparing 2-haloacrylic esters from 2-hydroxymethyl- or 2-halomethyl- or 2-chlorosulfinyloxymethyl-2-halomalonic diesters. The invention further provides novel 2-halomethyl-2-halomalonic diesters or 2-chlorosulfinyloxymethyl-2-halomalonic diesters which can be used for preparation of the 2-haloacrylic esters. | 2017-07-13 |
20170197906 | MONOMER AND POLYMER AND COMPENSATION FILM AND OPTICAL FILM AND DISPLAY DEVICE - A monomer is represented by Chemical Formula 1: | 2017-07-13 |
20170197907 | PROCESS TO PREPARE 3-METHYL-2-NITROBENZOIC ACID BY AIR OXIDATION - A method for preparing 3-methyl-2-nitrobenzoic acid is disclosed wherein 1,3-dimethyl-2-nitrobenzene is combined with an oxidation catalyst in the presence of an oxygen source and an initiator, provided that less than 99% of the 1,3-dimethyl-2-nitrobenzene is oxidized. | 2017-07-13 |
20170197908 | SYNTHESIS OF 4-AMINO-2, 4-DIOXOBUTANOIC ACID - A synthesis method comprises opening an anhydride to a 4-carbon acid-amide, removing ethanol soluble products, treating the resulting 4-amino-2-methylene-4-oxo-butanoic acid with Ozone in water, and evaporating the ozonolysis products to synthesize 4-amino-2,4-dioxobutanoic acid. | 2017-07-13 |
20170197909 | ENHANCED EXTRACTION OF IMPURITIES FROM MIXTURE COMPRISING NITRILES - Disclosed herein are methods for recovering phosphorus-containing ligand from mixtures comprising organic mononitriles and organic dinitriles, using liquid-liquid extraction. Also disclosed are treatments to enhance extractability of the phosphorus-containing ligand. | 2017-07-13 |
20170197910 | SUBSTITUTED VINYL AND ALKYNYL CYANOCYCLOALKANOLS AND VINYL AND ALKYNYL CYANOHETEROCYCLOALKANOLS AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS - Substituted vinyl- and alkynylcyanocycloalkanols and vinyl- and alkynylcyanoheterocyclylalkanols of the general formula (I) or salts thereof | 2017-07-13 |
20170197911 | ORTHO-ALKYNYL ANILINES AND PROCESS FOR PREPARATION THEREOF - The present invention relates to novel ortho alkynyl anilines of formula (I) which are useful in synthesis of drug intermediates and natural products and process for preparation of these ortho alkynyl anilines of formula (I) via copper catalyzed Multi Component Reactions (MCR). [Formula should be inserted here] Formula (I) | 2017-07-13 |
20170197912 | SYNTHESIZING PET TRACERS USING [F-18]SULFONYL FLUORIDE AS A SOURCE OF [F-18]FLUORIDE - The present disclosure relates to the methods for the preparation of reactive [F-18]fluoride in a form of [F-18]sulfonyl fluoride suitable for efficient radiolabeling without an azeotropic evaporation step by the use of anion exchange resin and sulfonyl chloride, and its applications in the manufacturing of PET radiopharmaceuticals. | 2017-07-13 |
20170197913 | METHOD FOR PREPARING POLYARYLENE SULFIDE (PAS) MONOMER - A method for preparing a cationic sulfoxide intermediate having the following formula | 2017-07-13 |
20170197914 | METHOD FOR PREPARING AN AROMATIC SULFIDE OR SALT THEREOF - A method for preparing an aromatic sulfide or a salt thereof is provided. The method for preparing an aromatic sulfide or a salt thereof includes reacting a compound having a structure represented by Formula (I) to a compound having a structure represented by Formula (III) in the presence of a compound having a structure represented by Formula (II) to obtain a compound having a structure represented by Formula (IV) | 2017-07-13 |
20170197915 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF - Described herein are compounds that are estrogen receptor modulators of Formula (I): | 2017-07-13 |
20170197916 | FUNCTIONALIZED PEGYLATED CYANINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF - Provided herein are functionalized pegylated cyanine compounds containing a reactive group suitable for labeling a biomolecule or pharmaceutical compositions and methods of use thereof. In one embodiment, the compounds are based on formula I shown below. | 2017-07-13 |
20170197917 | METHOD FOR PRODUCING INDOLINE COMPOUND - Provided is a salt including a compound represented by a formula (4) and a compound represented by a formula (5). A method for producing the salt includes reacting a compound represented by a formula (2) with a compound represented by a formula (3) in the presence of a quaternary onium salt and a base to form the compound represented by the formula (4); and mixing the compound represented by the formula (4) with the compound represented by the formula (5). A method for producing a compound represented by a formula (6) includes removing, from the salt including the compounds of formulae (4) and (5), a protecting group P | 2017-07-13 |
20170197918 | Allosteric Modulators of CB1 Cannabinoid Receptors - The present invention relates to novel heterocyclic derivatives which are allosteric modulators of cannabinoid receptor 1 (CB1) and which are useful for the treatment or prevention of neurological and psychiatric disorders associated with endocannabinoid dysfunction and diseases in which the CB1 subtype of cannabinoid receptor is involved; to processes for their preparation; to pharmaceutical compositions comprising them; and to methods of using them. | 2017-07-13 |
20170197919 | 3-(Carboxyethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives - The invention relates to 3-(carboxyethyl)-8-amino-2-oxo-1,3-diazaspiro-[4.5]-decane derivatives, their preparation and their use in medicine, particularly in the treatment of pain. | 2017-07-13 |
20170197920 | FLUOROALKYLATING AGENT - Problem to be Solved | 2017-07-13 |
20170197921 | BENZIMIDAZOL-2-AMINES AS MIDH1 INHIBITORS - The present invention relates to benzimidazol-2-amines of general formula (I), in which R | 2017-07-13 |
20170197922 | BENZIMIDAZOL-2-AMINES AS MIDH1 INHIBITORS - The present invention relates to benzimidazol-2-amines of general formula (I): in which R | 2017-07-13 |
20170197923 | Bifunctional Compounds and Use for Reducing Uric Acid Levels - Bifunctional compounds that increase uric acid excretion and reduce uric acid production. Methods of using these compounds for reducing uric acid levels in blood or serum, for treating disorders or uric acid metabolism, and for maintaining normal uric acid levels in blood or serum are provided. Pharmaceutical compositions comprising the bifunctional compounds are also provided. | 2017-07-13 |
20170197924 | Novel 1,2,3 Triazole Antifungal Agents and Preparation Thereof - The present application relates to 1,4-disubstituted 1,2,3-Triazole antifungal agents of the formula (I) wherein, R1 is halogens such as fluorine, chlorine or bromine, CF3, alkyl; R2 is alkyl or hydrogen; R3 is halogen selected from fluorine, chlorine or bromine; and n is 0 or 1. The application further relates to the synthesis of said compounds, to fungicidal compositions containing said compounds and to their use in a method for treating fungal infections. | 2017-07-13 |
20170197925 | METHOD FOR PREPARING 3-TRIFLUOROMETHYL CHALCONES - Disclosed is a method for preparing a compound of Formula 1 wherein Q and Z are as defined in the disclosure comprising distilling water from a mixture comprising a compound of Formula 2, a compound of Formula 3, a base comprising at least one compound selected from the group consisting of alkaline earth metal hydroxides of Formula 4 wherein M is Ca, Sr or Ba, alkali metal carbonates of Formula 4a wherein M | 2017-07-13 |
20170197926 | HERBICIDALLY ACTIVE BENXZOIC ACID AMIDES - The invention relates to benzoic acid amides of general formula (I) as herbicides. In formula (I) X, Z and R represent radicals such as alkyl and cycloalkyl. Q represents a 5-membered heterocycle. | 2017-07-13 |
20170197927 | DEUTERIUM SUBSTITUTED 1-[2-(2,4-DIMETHYL-PHENYLSULFANYL) -PHENYL]PIPERAZINE COMPOUND OR DERIVATIVES THEREOF, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF - The present disclosure provides a deuterium substituted 1-[2-(2,4-dimethyl-phenylsulfanyl)-phenyl]piperazine compound with a structure represented by formula (I) or a derivative thereof, a pharmaceutical composition containing the compound or the derivative thereof, and an application of the compound or the derivative thereof in preparing drugs. The compound can reduce oxidative metabolism thereof, increase the drug concentration in blood and the effective bioavailability, so as to lower the dosage and reduce the toxicity and other side effects. The deuterium 1-[2-(2,4-dimethyl-phenylsulfanyl)-phenyl]piperazine compound and its derivative thereof provided by the present disclosure can be used to treat related diseases such as affective disorders, depression and anxiety. | 2017-07-13 |
20170197928 | ARYL COMPOUND AND MAKING METHOD - An aryl compound terminated with at least three glycidyl groups and at least three (meth)allyl groups, having formula (1) wherein R | 2017-07-13 |
20170197929 | CHELATE-CONTROLLED DIASTEREOSELECTIVE HYDROGENATION WITH HETEROGENEOUS CATALYST - A catalyst, method of using, and use of a hydrogenation catalyst, preferably palladium on a support, preferably alumina or activated charcoal support. This in the presence of lithium salts, with salts such as the borates being preferred. This provides hydrogenation of precursors to give rise to a stereoselective, such as diastereoselective bias in the product of alkene hydrogenation using the catalyst. | 2017-07-13 |
20170197930 | PROCESSES FOR THE PREPARATION OF 2,5-FURANDICARBOXYLIC ACID AND INTERMEDIATES AND DERIVATIVES THEREOF - The present disclosure provides processes for the production of 2-5-furandicarboxylic acid (FDCA) and intermediates thereof by the chemocatalytic conversion of a furanic oxidation substrate. The present disclosure further provides processes for preparing derivatives of FDCA and FDCA-based polymers. In addition, the present disclosure provides crystalline preparations of FDCA, as well as processes for making the same. | 2017-07-13 |
20170197931 | APPARATUS AND METHOD FOR PRODUCING CYCLIC CARBONATE - Disclosed herein are an apparatus and method for continuously producing a cyclic carbonate. The apparatus includes an adiabatic reactor to be filled with a heterogeneous catalyst for reacting an epoxide with carbon dioxide, a circulation path for returning at least a portion of a fluid mixture in a liquid form flowed out through a reactor outlet into the reactor, a carbon dioxide supply means for continuously supplying carbon dioxide in a liquid form or a supercritical state into the circulation path, and an epoxide supply means for continuously supplying an epoxide in a liquid or solution form into the circulation path. | 2017-07-13 |
20170197932 | NOVEL STAT3 PATHWAY INHIBITORS AND CANCER STEM CELL INHIBITORS - The present invention relates to a novel naphtho class of compounds as Stat3 pathway inhibitors and as cancer stem cell inhibitors; to methods of using such compounds to treat cancer; to methods of using such compounds to treat disorders in a mammal related to aberrant Stat3 pathway activity; to pharmaceutical compositions containing such compounds. | 2017-07-13 |
20170197933 | ANTIPROLIFERATIVE COMPOUNDS, AND THEIR PHARMACEUTICAL COMPOSITIONS AND USES - Compounds of formula A-I and B-I, compositions comprising the compounds, methods of making the compounds and methods of their uses are disclosed. | 2017-07-13 |
20170197934 | SOLID FORMS OF 2-(4-CHLOROPHENYL)-N-((2-(2,6-DIOXOPIPERIDIN-3-YL)-1-OXOISOINDOLIN-5-YL)M- ETHYL)-2,2-DIFLUOROACETAMIDE, AND THEIR PHARMACEUTICAL COMPOSITIONS AND USES - Solid forms comprising 2-(4-chlorophenyl)-N-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)-2,2-difluoroacetamide, compositions comprising the solid forms, methods of making the solid forms and methods of their uses are disclosed. | 2017-07-13 |
20170197935 | INHIBITORS OF DNA GYRASE FOR THE TREATMENT OF BACTERIAL INFECTIONS - The present invention relates to compounds which specifically inhibit bacterial DNA Gyrase and can be used for the treatment of respiratory tract infections. | 2017-07-13 |
20170197936 | ENANTIOMERS OF 8-HYDROXYQUINOLINE DERIVATIVES AND THE SYNTHESIS THEREOF - Our invention relates to novel enantiomer derivatives of 8-hydroxyquinoline derivatives with general formula (I) and (II) and the synthesis thereof and pharmaceutically acceptable salts and metal complexes thereof, and the medicinal and/or pharmaceutical compositions comprising these compounds. | 2017-07-13 |
20170197937 | NEW CRYSTAL FORM OF PANTOPRAZOLE SODIUM COMPOUND AND PREPARATION METHOD THEREFOR - A novel crystalline form is defined by using diffraction angle 2θ° of X-ray powder diffraction pattern and characteristic peaks of differential scanning calorimetry (DSC). Pantoprazole Sodium solid is added to an alcohol solvent to form a suspension with a concentration of 0.05˜0.2 g/mL, and then an antioxidant is added to the suspension, completely dissolving the solid at a temperature of 15˜35° C., and a solventing-out agent is dropwise added to the solution under the application of ultrasonic wave, wherein the amount of the solventing-out agent is 3˜10 times (in volume) of the alcohol solvent; followed by cooling the solution down to 0˜5° C., continuing to stir for 1˜3 h, and suction filtrating obtained solid-liquid suspension to provide a novel crystalline form of Pantoprazole Sodium crystal after drying the product to constant weight. | 2017-07-13 |
20170197938 | A QUINOLINE DERIVATIVE FOR THE TREATMENT OF INFLAMMATORY DISEASES AND AIDS - The present invention relates to a compound of formula (1) in the form of a base or addition salt with an acid, particularly a pharmaceutically acceptable acid. It further relates to a pharmaceutical composition including the compound and at least one pharmaceutically acceptable excipient, to a process for preparing said compound and to a corresponding intermediate compound. | 2017-07-13 |
20170197939 | Tropomyosin-Related Kinase Inhibitors Containing Both A 1H-Pyrazole And A Pyrimidine Moiety - The present invention relates to compounds of Formula I | 2017-07-13 |
20170197940 | INDANE AND INDOLINE DERIVATIVES AND THE USE THEREOF AS SOLUBLE GUANYLATE CYCLASE ACTIVATORS - The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition. | 2017-07-13 |
20170197941 | CYCLOHEXEN-1-YL-PYRIDIN-2-YL-1H-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF AS SOLUBLE GUANYLATE CYCLASE ACTIVATORS - The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition. | 2017-07-13 |
20170197942 | SELECTIVE METHODS FOR THE SEPARATION OF ONDANSETRON AND RELATED IMPURITIES - The present disclosure generally relates to methods for separating ondansetron and related impurities using CO | 2017-07-13 |
20170197943 | PROCESS FOR PRODUCING ALKYNYLKETONE DERIVATIVE - The present invention relates to a Sonogashira-Carbonylation reaction using two types of gas, as well as novel crystals which can control a heat of the said reaction and the process of producing the same. In addition, the present invention relates to a ligand (additive) to prevent the deactivation of a palladium catalyst. | 2017-07-13 |
20170197944 | PROCESS FOR THE PREPARATION OF LEDIPASVIR - An improved process is provided for the preparation of Ledipasvir and its pharmaceutically acceptable salts or solvates thereof, which is useful as an antiviral agent. This disclosure also provides a process for the preparation of key intermediates of Ledipasvir. | 2017-07-13 |
20170197945 | 2-SUBSTITUTED QUINAZOLINE COMPOUNDS COMPRISING A SUBSTITUTED HETEROCYCLIC GROUP AND METHODS OF USE THEREOF - Compounds having activity as inhibitors of G12C mutant KRAS protein are provided. The compounds have the following structure (I): | 2017-07-13 |
20170197946 | KOJIC ACID-DERIVED MANNICH BASES WITH BIOLOGICAL EFFECT - The present invention relates to kojic acid-derived mannich base compounds with biological effect, and hydrates, solvates, pharmacologically acceptable salts or geometric isomers thereof. Said compounds have antidermatophytic, antimycobacterial, antityrosinase, anti-aging and antioxidant effect. | 2017-07-13 |
20170197947 | 3-((Hetero-)Aryl)-Alkyl-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives - The invention relates to 3-((hetero-)aryl)-alkyl-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives, their preparation and their use in medicine, particularly in the treatment of pain. | 2017-07-13 |
20170197948 | METHOD FOR PRODUCING CARBOXYLIC ANHYDRIDE - Method for producing carboxylic anhydride, the method includes heating raw material compound represented by the following general formula (1): | 2017-07-13 |
20170197949 | 8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives - The invention relates to 8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives, their preparation and their use in medicine, particularly in the treatment of pain. | 2017-07-13 |
20170197950 | THIOPHEN-2-YL-PYRIDIN-2-YL-1H-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF AS SOLUBLE GUANYLATE CYCLASE ACTIVATORS - The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition. | 2017-07-13 |
20170197951 | Process of Preparing Potassium Salt of Azilsartan Medoxomil - The present invention relates to a process for the preparation of Azilsartan Medoxomil Potassium. The invention further relates to novel highly crystalline polymorph of Azilsartan Medoxomil Potassium and composition comprising it. The invention provides thermostable highly crystalline polymorph of Azilsartan Medoxomil Potassium and process to produce a composition comprising the novel highly crystalline polymorph of Azilsartan Medoxomil Potassium. | 2017-07-13 |
20170197952 | THIAZOLIDINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS AND INFLAMMATION, IN PARTICULAR NEUROINFLAMMATION - The invention relates to a compound comprising the following general formula (1) and said compound for use as a medicament, in particular for use in the treatment psychiatric or neurological disorders and inflammation, in particular neuroinflammation: (formula 1) wherein each of R | 2017-07-13 |
20170197953 | FACTOR XIa INHIBITORS - The present invention provides a compound of Formula I (The chemical formula should be inserted here.) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIa inhibitors or dual inhibitors of Factor XIa and plasma kallikrein. | 2017-07-13 |
20170197954 | 1,3,4-Thiadiazole compounds and their use in treating cancer - The specification relates to compounds of Formula (I), and pharmaceutically acceptable salts thereof, where Q, R, R | 2017-07-13 |
20170197955 | 2-ACYLAMINOTHIAZOLE DERIVATIVE OR SALT THEREOF | 2017-07-13 |
20170197956 | BENZOTHIAZOLE COMPOUND AND MEDICINE CONTAINING SAME - It is intended to provide: a compound useful as an amyloid oxidation catalyst which is applicable in vivo and is applicable not only to Aβ peptides but to other amyloids; and a prophylactic or therapeutic drug for an amyloid-related disease, comprising the same. The present invention provides a benzothiazole compound represented by the following formula (1) wherein X represents a halogen atom; R | 2017-07-13 |
20170197957 | METHODS OF MANUFACTURING BENZOQUINOLINE COMPOUNDS - The present invention relates to new methods of manufacturing benzoquinoline inhibitors of vesicular monoamine transporter 2 (VMAT2), and intermediates thereof. | 2017-07-13 |
20170197958 | AGONISTS OF THE APELIN RECEPTOR AND METHODS OF USE THEREOF - Provided herein are small molecule agonists of the apelin receptor for the treatment of disease. The compounds disclosed herein are useful for the treatment of a range of cardiovascular, renal and metabolic conditions. The present invention is based on the seminal discovery of a series of potent small molecule agonists of the apelin receptor, which are useful for the treatment of diseases including heart failure, chronic kidney disease, hypertension, and metabolic disorders such as insulin resistance/diabetes and obesity. The compounds disclosed herein are highly specific for the apelin receptor versus the angiotensin II receptor (ATI). | 2017-07-13 |
20170197959 | Pyridopyrimidinedione derivatives - The invention relates to compound of the formula (I) or a salt thereof, wherein the substituents are as defined in the specification; to its preparation, to its use as medicament and to medicaments comprising it. | 2017-07-13 |
20170197960 | ATX MODULATING AGENTS - Compounds of formula (I) can modulate the activity of autotaxin (ATX). | 2017-07-13 |
20170197961 | SERINE DERIVATIVES AS GHRELIN RECEPTOR AGONISTS - The present invention relates to novel compounds of formula (I) or a pharmaceutically acceptable salt or solvate thereof, processes for their preparation, pharmaceutical compositions containing them and their use in therapy, for example as modulators of the growth hormone secretagogue receptor (also referred to as the ghrelin receptor or GHSRla receptor) and/or for the treatment and/or prophylaxis of a disorder mediated by the ghrelin receptor. | 2017-07-13 |
20170197962 | HETEROARYL COMPOUNDS FOR KINASE INHIBITION - Compounds and pharmaceutical compositions that modulate kinase activity, including mutant EGFR and mutant HER2 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including mutant EGFR and mutant HER2 activity, are described herein. | 2017-07-13 |
20170197963 | Process for preparation of (2S, 5R)-7-oxo-6-sulphooxy-2-[((3R)-piperidine-3-carbonyl)-hydrazino carbonyl]-1,6-diaza-bicyclo [3.2.1]-octane - A process for preparation of (2S, 5R)-7-oxo-6-sulphooxy-2-[((3R)-piperidine-3-carbonyl)-hydrazino carbonyl]-1,6-diaza-bicyclo[3.2.1]octane is disclosed. | 2017-07-13 |