25th week of 2019 patent applcation highlights part 41 |
Patent application number | Title | Published |
20190187041 | SYSTEM AND METHOD FOR CHARACTERIZATION OF INCLUSIONS IN LIQUID SAMPLES - Described are systems and methods for optical characterization of inclusions, such as solids and liquids, in liquid samples. An inclusion characterization system may include a radiation source, a radiation detector, a sample optical cell, and a sample delivery mechanism. The radiation detector may be configured to perform time resolved measurements. The sample may be delivered to the sample optical cell by the sample delivery mechanism at a flow rate set for preserving the sample integrity (i.e., the transport rate). The inclusion characterization in the sample may be performed at flow rates set for sample analysis (i.e., the analysis rate). The analysis rate may differ from the transport rate. The rate difference may be achieved by diverting only a portion of the overall sample into the sample optical cell. Also provided are examples of disengagement of sample transport and analysis flow rates. | 2019-06-20 |
20190187042 | SCANNING INFRARED MEASUREMENT SYSTEM - An analyzer of a component in a sample fluid includes an optical source and an optical detector defining a beam path of a beam, wherein the optical source emits the beam and the optical detector measures the beam after partial absorption by the sample fluid, a fluid flow cell disposed on the beam path defining an interrogation region in the a fluid flow cell in which the optical beam interacts with the sample fluid and a reference fluid; and wherein the sample fluid and the reference fluid are in laminar flow, and a scanning system that scans the beam relative to the laminar flow within the fluid flow cell, wherein the scanning system scans the beam relative to both the sample fluid and the reference fluid. | 2019-06-20 |
20190187043 | USE OF VIBRATIONAL SPECTROSCOPY FOR DNA CONTENT INSPECTION - This disclosure concerns a cytometry system including a handling system that enables presentation of single cells to at least one laser source. The laser source is configured to deliver light to a cell within the cells in order to induce bond vibrations in the cellular DNA. The system further includes a detection facility that detects the signature of the bond vibrations, wherein the bond vibration signature is used to determine the folding or packing of the DNA. | 2019-06-20 |
20190187044 | MICROFLUIDIC SYSTEM AND METHOD WITH FOCUSED ENERGY APPARATUS - A method of inseminating an animal including flowing a stream of a population of sperm cells through a channel, differentiating the sperm cells into two subpopulations of X-chromosome containing sperm cells and Y-chromosome containing sperm cells, selecting a desired subpopulation, ablating an undesired subpopulation, and collecting both the subpopulations of sperm cells including the desired subpopulation and the ablated undesired subpopulation together, wherein the collected population of sperm cells is used to fertilize an egg. | 2019-06-20 |
20190187045 | FLOW CELL - A flow cell includes a housing, a window member, and a pressing member. The housing includes a cell channel in which a sample flows through, has, on at least one end side of the cell channel, an opening communicating with the cell channel, and has a flat surface at an edge of the opening. The window member has a lens portion at a central portion and a peripheral edge portion whose one surface and the other surface are flat. In the window member, one surface of the peripheral edge portion is provided facing the flat surface of the housing so as to seal the opening. | 2019-06-20 |
20190187046 | SPECTROMETRIC PROBE FOR SAMPLING BULK MATERIAL AND AUTOMATIC SAMPLE TAKER FOR SAMPLING INCLUDING THE PROBE - A spectrometric probe for sampling of bulk material and automatic sampler for sampling bulk material, which allows to obtain the composition parameters of the material to be sampled directly, avoiding the extraction and transfer of samples that shall be examined in external sections under the observation and analysis of trained and specialized personnel, thus optimizing operation times and reducing related costs. | 2019-06-20 |
20190187047 | IN-SITU DAMAGE DETECTION SYSTEM FOR MECHANOPHORE-EMBEDDED FIBER REINFORCED COMPOSITES - Methods and systems are provided for detecting mechanophore damage in a composite material where the mechanophores are embedded in a matrix of the composite material. A mechanical load is applied to the composite material. A damage precursor signal is generated as a result of the mechanical load and is detected before yield of the mechanophore embedded composite material. Detecting the damage precursor signal may include illuminating the mechanophore embedded composite material with UV light to excite the embedded mechanophores, capturing fluorescent emissions of the embedded mechanophores with a UV camera, and filtering light received at the UV camera based on an emission wavelength of the mechanophores. Alternatively, the damage precursor signal may be detected using spectra from an evanescent wave distorted by the mechanophore embedded composite material using an attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR) system. | 2019-06-20 |
20190187048 | SPECTROSCOPIC SYSTEMS AND METHODS FOR THE IDENTIFICATION AND QUANTIFICATION OF PATHOGENS - A system for detecting a disease agent in a sample derived from a patient biofluid may comprise a receiver coupled to a communication network and a controller coupled to the receiver. The controller may comprise a processor and a memory. The controller may be configured to generate an infrared spectrum of the sample. The sample spectrum may comprise one or more sample spectral components, the sample spectral components comprising a sample wavenumber and a sample absorbance value. A set of reference spectral models may comprise one or more reference spectral components. The reference spectral components may comprise a reference wavenumber and a reference absorbance value. The reference spectral components may comprise one or more pathogen characteristics associated with sepsis. The one or more sample spectral components may be classified as pathogenic using the reference spectral models. Pathogen data may be generated using the classified sample spectral components. | 2019-06-20 |
20190187049 | Method for Quantifying the Amount of Ammonium Bicarbonate in a Solid Sample of Ammonium Bicarbonate - A method for quantifying the amount of ammonium bicarbonate in a solid sample of ammonium carbamate is provided. The method includes measuring the FT-IR spectrum of the sample, calculating the IR band maximum for a first band that is common to ammonium carbamate and ammonium bicarbonate and for a second band that is unique to ammonium carbamate, calculating a ratio of the maximum of the second band to the maximum of the first band, and calculating the concentration of ammonium bicarbonate in the sample from a calibration curve. | 2019-06-20 |
20190187050 | METHOD AND SYSTEM FOR REMOTE INSPECTION OF INDUSTRIAL ASSETS - An inspection apparatus includes a communication unit including a first transmitter and a second transmitter. The communication unit is coupled to an on-board computing device including at least one processor coupled to a memory device. The processor is configured to obtain a position of the inspection apparatus, unprocessed image data, and fluid concentration data for at least one fluid. The processor geotags the data with the position of the inspection apparatus and transmits the data to a remote processing device. The geotagged image data is transferred using the first transmitter and the geotagged fluid concentration data is transmitted using the second transmitter. | 2019-06-20 |
20190187051 | TUNABLE DIODE LASER ABSORPTION SPECTROSCOPY WITH CORRECTED LASER RAMPING NONLINEARITIES - A tunable diode laser absorption spectroscopy device includes a tunable diode laser. A laser driver is configured to drive the diode laser and ramp it within a particular frequency range. An analyte gas container, a reference gas container, and a fringe generating device are configured to receive the laser therethrough. An optical detector is configured to detect the laser after it has passed through the analyte gas container and/or the reference gas container, and the in-line fringe generating device. An acquisition card is configured to sample an output of the optical detector. A spectral analyzer is configured to receive output data from the acquisition card, determine a spectrum of the output data, decouple the fringe spectrum from the measured spectrum, calibrate the spectrum based on an expected ideal spectrum of both the fringe and reference gas, and determine a composition of the analyte based on the calibrated spectrum. | 2019-06-20 |
20190187052 | MATERIAL FOR DETECTING PHOTORESIST AND METHOD OF FABRICATING SEMICONDUCTOR DEVICE USING THE SAME - Provided are a material for detecting photoresist and a method for detecting photoresist using the same. The material for detecting photoresist may include a macrocyclic molecule having a hollow structure and a fluorescent substance which is labeled on the macrocyclic molecule, and the macrocyclic molecule is at least one of cyclodexrin, cucurbituril, calixarene, pillararene and catenane. | 2019-06-20 |
20190187053 | OPTICAL MICROSCOPY WITH PHOTOTRANSFORMABLE OPTICAL LABELS - Imaging a sample that includes phototransformable optical labels (“PTOLs”) with an optical system having a diffraction-limited resolution volume (DLRV), includes providing activation radiation to the PTOLs to activate a statistical subset of the PTOLs. A density of the PTOLs of the activated subset is less than an inverse of the DLRV. Excitation radiation is provided to the activated subset to excite activated PTOLs. Radiation emitted from the activated and excited PTOLs located at different focal planes of the optical system within the sample is detected with the optical system. The preceding steps are repeated one or more times, each time activating a different statistical subset of the plurality of PTOLs. Three-dimensional locations within the sample are determined, with a sub-diffraction-limited accuracy, of the activated and excited PTOLs based on the radiation emitted from the activated and excited PTOLs that is detected from the different focal planes of the optical system. | 2019-06-20 |
20190187054 | APPARATUS FOR DETECTING FLUORESCENT SIGNALS EMITTED BY SAMPLES - Various embodiments are directed to a fluorescence reader for assessing a fluorescence intensity of one or more substance samples. The fluorescence reader may comprise a sample support structure for accepting sample wells containing corresponding samples therein, an illumination structure positioned below the sample support structure and configured to illuminate one or more samples positioned within the sample wells, and an imaging structure positioned above the sample support structure and configured to detect a fluorescence emitted by the one or more samples. The illumination structure may comprise one or more reflective perimeter walls, together with the support structure, defining an enclosed illumination cavity, and one or more light sources positioned within the enclosed illumination cavity and configured to emit light causing the one or more samples to fluoresce. | 2019-06-20 |
20190187055 | DETECTION OF PHYSICAL FORENSIC EVIDENCE - Detecting physical forensic evidence on a surface includes contacting the surface with a composition, the composition including a rare-earth metal and a chelator. The composition contacting the surface is illuminated with electromagnetic radiation configured to cause the composition to fluoresce in a pattern indicative of physical forensic evidence. The pattern indicative of physical forensic evidence can then be captured. The composition can be made by combining a rare-earth metal, a chelator, and a solvent to form a solution, precipitating the rare-earth metal and the chelator in the solution, and isolating the precipitate of the rare-earth metal and the chelator from a remainder of the solution. The resulting composition includes a porous metal-organic framework of a rare-earth metal and a chelator, where the pores range in diameter from about 0.01 nm to about 50 nm. | 2019-06-20 |
20190187056 | POROUS PLANAR CELL CAPTURE SYSTEM - The invention relates to a porous planar cell capture system for use in determining the presence and/or amount of cells, for example, viable cells, in a liquid sample, and to methods of using such a cell capture system. The cell capture system contains a fluid permeable, planar membrane adopted to retain cells thereon, a fluid permeable support member that supports the membrane, and an optional register associated with the membrane. | 2019-06-20 |
20190187057 | BIOSENSOR, MANUFACTURING METHOD THEREOF AND BIOSENSING METHOD - A biosensor, and a preparation and biosensing method therefor. The biosensor includes: a sensing substrate, wherein a plurality of sensing suspending arms arranged in an array are arranged on the sensing substrate, and the sensing suspending arms have identification markers; and a detection substrate, the detection substrate including a plurality of light detection assemblies arranged in an array, wherein the light detection assemblies and the sensing suspending arms are arranged in one-to-one correspondence, each of the light detection assemblies includes a photodiode and a thin film transistor, and the photodiode is connected to the thin film transistor. | 2019-06-20 |
20190187058 | CALIBRATION REFERENCE BODY FOR FLUORESCENCE MEASUREMENT DEVICE - A reference body | 2019-06-20 |
20190187059 | PROFILE REACTOR FOR OPERANDO MEASUREMENTS - The invention pertains to a system for operando measurements that comprises,
| 2019-06-20 |
20190187060 | CONTINUOUS INTERLEAVED PROCESS FOR CONDUCTING AN ASSAY IN A MULTI-WELL PLATE - We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring. | 2019-06-20 |
20190187061 | METHODS AND APPARATUS FOR INFRARED AND MID-INFRARED SENSING - A sensing apparatus includes a light source to transmit a light beam, an input switch, a first sensing element, a second sensing element, and a detector. The input switch receives the light beam and includes a phase change material having a first state and a second state. The first sensing element receives the light beam from the input switch when the phase change material is in the first state and produces a first change in the light beam in response to a presence of a first analyte. The second sensing element receives the light beam from the input switch when the phase change material is in the second state and produces a second change in the light beam in response to a presence of a second analyte. The detector detects the first change and/or the second change in the light beam. | 2019-06-20 |
20190187062 | ENVIRONMENTAL SENSOR - A sensor has a transparent polymer aerogel, and sensing materials dispersed into the transparent, polymer aerogel, where the sensing materials change color in response to environmental conditions. A method of forming a sensor includes providing a substrate, forming a polymer aerogel layer on the substrate, and infusing the polymer aerogel layer with sensing molecules. | 2019-06-20 |
20190187063 | METHOD FOR MARKING AND AUTHENTICATING DIAMONDS AND PRECIOUS STONES - Method and systems are presented for authentication of precious stones, according to their natural ID and/or predetermined markings created in the stones, based on unique characteristic radiation response of the stone to predetermined primary radiation. | 2019-06-20 |
20190187064 | IMAGE PROCESSING SYSTEM, COMPUTER READABLE RECORDING MEDIUM, AND IMAGE PROCESSING METHOD - It is to perform image measurement under appropriate conditions according to a position in image data. An image processing device acquires a plurality of pieces of image data generated by imaging in a plurality of different light emission states of a plurality of light emitting units included in an illumination device. The image processing device generates image data to be used for image measurement on the basis of the plurality of pieces of acquired image data and a generation condition defined in association with the position in the image data. | 2019-06-20 |
20190187065 | LIGHTING APPARATUS, METHOD FOR PROVIDING LIGHTING SYSTEM, AND ROAD MANAGEMENT SYSTEM - A lighting apparatus that irradiates light on a vehicle is provided. The lighting apparatus includes: a first light source that emits light for illuminating a predetermined area; a memory that stores location information indicating a location of the lighting apparatus; a second light source that outputs, to the predetermined area, a light signal indicating the location information; and a first controller that controls the first light source and the second light source, and modulates the light signal output by the second light source, in accordance with the location information stored in the memory. | 2019-06-20 |
20190187066 | METHODS AND SYSTEMS FOR VISUAL INSPECTION - Systems for visually inspecting a surface of an object are provided, which includes a visual inspection head, and a positioning apparatus for controlling a position and/or an orientation of the visual inspection head with respect to the object. The visual inspection head includes a visual inspection module, and an angle controlling module for ensuring a predetermined angle of the visual inspection system with respect to an area to be inspected of the surface of the object. The angle controlling module may include a pointer for projecting a light beam onto the area to be inspected and a camera for determining whether the light beam is reflected substantially perpendicularly. The system is configured to move the visual inspection head relative to the object until the light beam is reflected substantially perpendicularly. Methods for visually inspecting a surface are also provided. | 2019-06-20 |
20190187067 | DETECTION SYSTEM FOR A MULTILAYER FILM AND METHOD THEREOF - A detection system for a multilayer film is provided. The detection system for a multilayer film includes a light source device, a first image capture device, a second image capture device and an image processing device. The light source device projects a pair of parallel incident light to a transparent multilayer film obliquely. The pair of parallel incident light is projected onto the transparent multilayer film for producing and enabling a forward scattered light and a back scattered light to be projected therefrom. The first image capture device captures the back scattered light to produce a first image. The second image capture device captures the forward scattered light to produce a second image. The image processing device is coupled to the first image capture device and the second image capture device. The image processing device is used to compares and detect the differences between the second image and the first image. | 2019-06-20 |
20190187068 | SiC EPITAXIAL WAFER, PRODUCTION METHOD THEREFOR, LARGE PIT DEFECT DETECTION METHOD, AND DEFECT IDENTIFICATION METHOD - A SiC epitaxial wafer in which a SiC epitaxial layer is formed on a 4H—SiC single crystal substrate having an off angle and a substrate carbon inclusion density of 0.1 to 6.0 inclusions/cm | 2019-06-20 |
20190187069 | System for Inspecting a Tank in a Ship - A system for inspecting a tank in a ship, the tank being suitable for containing cargo in bulk. The system has a support member for supporting at least one sensor means for producing sensor data related to the tank. Also, it has at least three suspending means with an elongated flexible member, adapted to connect to the support member, and a winch, with a motor, for winding a length of the elongated flexible member. Moreover, the system has a control unit for controlling the motor of the winches. The suspending means are adapted to suspend the support member in a position inside the tank. The control unit is configured to synchronize the length of the wound elongated flexible member with the position of the support member inside the tank. | 2019-06-20 |
20190187070 | Soldering Quality Detection Platform - A soldering quality detection platform comprises a 2D image acquisition device adapted to acquire a 2D image of a soldered region of a soldered product, a 3D image acquisition device adapted to acquire a 3D image of the soldered region of the soldered product, and a judgment device. The judgment device is adapted to determine whether a soldering quality is qualified based on the 2D image and the 3D image of the soldered region of the soldered product. | 2019-06-20 |
20190187071 | MEASURING DEVICE FOR DIELECTRIC CONSTANT DETERMINATION - The present disclosure relates to a measuring device for measuring a dielectric constant of fill substances in containers. The measuring device includes: a transmitting circuit for transmitting a first electromagnetic high-frequency signal and a second electromagnetic high-frequency signal; a receiving circuit for receiving the two high-frequency signals; and an evaluation circuit to ascertain a first phase shift between the transmitting and the receiving of the first high-frequency signal, to ascertain a second phase shift between the transmitting and the receiving of the second high-frequency signal, and to ascertain an amplitude of one of the received high-frequency signals. Based on these three values, the dielectric constant is determined. By determining phase shift at different frequencies, it is possible according to the present disclosure, especially in the case of solid-type fill substances, to determine their dielectric constant uncorrupted, thus without influence of air inclusions or moisture. | 2019-06-20 |
20190187072 | PLANT WATER SENSOR - The plant water Anomalous Phase sensor can determine moisture levels in plant leaves, stems and wood. The sensors described include several embodiments of the sensor, all of which estimate moisture levels by determining changes in the phase spectrum of an anomalous-phase resonator. Two embodiments include a planar transmitting antenna array with two slightly detuned patch antennas and a detector. In a first embodiment, the detector is a dipole antenna centered and out of plane with the transmitting antenna array. In a second embodiment, the detector is a singular rectangular patch antenna coplanar with the transmitting antenna array. The third embodiment is similar to the second embodiment, but is formed on a flexible substrate, so that the sensor can be wrapped about a twig, branch or other plant structure, in a non-coplanar arrangement. To compensate for temperature affects, a reference sensor may be integrated with an active sensor. | 2019-06-20 |
20190187073 | SYSTEM AND METHOD FOR CABINET X-RAY SYSTEMS WITH CAMERA - The present disclosure relates to the field of a cabinet x-ray incorporating an x-ray tube, an x-ray detector, and a real-time camera, either high definition or standard resolution, for the production of organic and non-organic images. The computing device can receive video data from the camera and the x-ray detector and determines, based on the video data, an overlay of the captured x-ray image with the captured real-time image or display images adjacently i.e. Picture-In-Picture (PIP). In particular, the disclosure relates to a system and method with corresponding apparatus for capturing a real-time image simultaneously with the x-ray image allowing a cabinet x-ray unit to attain and optimize images with exact orientation of the 2 images. | 2019-06-20 |
20190187074 | Analytical Methods - The disclosure contains a method of quantifying and/or evaluating metal ions in a dentifrice, wherein the method comprises subjecting the dentifrice to X-ray absorption spectroscopy (XAS), and wherein the XAS is used to measure and/or evaluate the metal ions in the dentifrice. Also disclosed are methods of selecting and screening for dentifrices based upon the evaluation and quantification of their metal ion content. | 2019-06-20 |
20190187075 | SYSTEM FOR DETECTING AND REAL TIME PROCESSING X-RAY PULSES FROM MICROCALORIMETER DETECTORS - An x-ray spectrometer system includes: an excitation source that produces excitation particles and irradiates a sample with the excitation particles such that the sample produces x-rays; thermal detectors that: detect the x-rays from the sample; and produce digital x-ray data in response to detecting the x-rays from the sample, the x-ray data including x-ray pulses; and an analyzer that includes a multichannel receiver that receives, in parallel, the digital x-ray data from the thermal detectors and that: rejects pulse pileup in the digital x-ray data and produces pass data from the digital x-ray data; subjects the pass data to an optimal filter to produce filter data; determines a pulse height of x-ray pulses in the filter data to produce pulse data; combines the pulse data to produce combined data; and calibrates the combined data to produce calibrated data. | 2019-06-20 |
20190187076 | SET-UP AND METHOD FOR SPATIALLY RESOLVED MEASUREMENT WITH A WAVELENGTH-DISPERSIVE X-RAY SPECTROMETER - X-ray spectrometer comprising an X-ray source emitting X-ray radiation onto a sample, a collimator arrangement for collimating X-ray radiation that has passed through a diaphragm arrangement, the collimator arrangement comprising a modified Soller slit with mutually parallel lamellae forming a plurality of slit-shaped passages, at least a portion of the slit-shaped passages having partition walls aligned substantially perpendicularly to the slit-shaped passages, the partition walls being non-transmissive to X-ray radiation and restricting the transverse divergence of the X-ray radiation passing through the collimator arrangement in a direction transversely with respect to the diffraction plane of the X-ray radiation coming from the sample. Significantly faster spatially resolved measurements can thus be carried out. | 2019-06-20 |
20190187077 | APPARATUS FOR X-RAY INSPECTION, AND A METHOD FOR MANUFACTURING A SEMICONDUCTOR DEVICE USING THE SAME - An apparatus for X-ray inspection is provided. The apparatus includes: a stage on which an inspection target is loaded, the stage including a first surface and an opposite second surface; an X-ray generator disposed on or over the first surface of the inspection target and configured to irradiate the inspection target with incident X-rays; and a detection system disposed on or under the second surface of the inspection target and configured to detect first transmitted X-rays transmitted through the inspection target. The detection unit includes a first lens system and a second lens system. The first transmitted X-rays pass through one of the first lens system and the second lens system. The second lens system includes a micro zone plate. | 2019-06-20 |
20190187078 | X-RAY DETECTION APPARATUS AND X-RAY DETECTION METHOD - An X-ray generation apparatus comprising: an X-ray generating unit; a dispersive crystal whose surface is irradiated with an X-ray generated from the X-ray generating unit in order to monochromatize the X-ray; and a detecting unit that detects an X-ray generated from a sample irradiated with the X-ray monochromatized by the dispersive crystal. The dispersive crystal has a single-bent shape containing the surface that is a concave surface formed by integrating concave curve lines continuously along an axis perpendicular to a plane including the concave curve line. A direction in which a position on the surface irradiated with the X-ray generated from the X-ray generating unit moves is the direction along the axis. | 2019-06-20 |
20190187079 | IMPROVED ANALYSIS WITH PRELIMINARY SURVEY - A method and apparatus for analysis of a specimen in a microscope are provided. A first survey is performed that collects analytical data from a region of interest on the specimen surface using a first set of conditions. A second survey is performed that collects additional analytical data from selected parts of the region of interest on the specimen surface using a second set of conditions, different from the first set of conditions. The analytical data from the first survey is used to select the parts used for data collection in the second survey and to decide the order in which they are used. | 2019-06-20 |
20190187080 | Method and Apparatus for Sample Analysis - A method of sample analysis is offered which provides improved quantitative accuracy. This method starts with irradiating a sample with an electron beam. Characteristic X-rays emanating from the sample are detected. Plural data sets about intensities of characteristic X-rays corresponding to a specific element contained in the sample are obtained. The element is quantitatively analyzed based on the plural data sets. This method includes a step (S | 2019-06-20 |
20190187081 | INVERTER DEVICE AND METHOD FOR DETECTING HEAT DISSIPATION CHARACTERISTICS OF INVERTER DEVICE - According to one embodiment, an inverter device configured to be capable of switching an on or off state of each of a plurality of switching elements, on the basis of a control command signal, and operable as a single-phase inverter, includes: a pulse width modulator configured to set a voltage value at a time when one of the switching elements is set to the on state to a first voltage, and set a voltage value at a time when the other three of the switching elements are set to the on state to a second voltage larger than the first voltage, in operation as the single-phase inverter; and a detection unit configured to detect the control command signal in operation as the single-phase inverter. | 2019-06-20 |
20190187082 | ULTRASENSITIVE SENSOR BASED ON A PIEZOELECTRIC TRANSISTOR - Chemical sensors and methods of using and making the same include a functionalized electrode configured to change surface potential in the presence of an analyte. A piezoelectric element is connected to the functionalized electrode and is configured to change in volume in accordance with the surface potential of the functionalized electrode. A piezoresistive element is in contact with the piezoelectric element and is configured to change in resistance in accordance with the volume of the piezoelectric element. | 2019-06-20 |
20190187083 | ELECTROMAGNETIC SENSOR - Provided is an electromagnetic sensor capable of stably measuring electric conductivity and the like even in the case where solid matters are mixed in a sample solution. The electromagnetic sensor includes a substrate, a through hole formed in the substrate, an electrode attached to a surface of the substrate, and a housing that covers the through hole and the electrode, and in this configuration, the sample solution supplied to a surface of the substrate opposite to the surface of the substrate having the electrode attached thereto is allowed to flow into the housing from the through hole and to be accommodated in the housing, so that the sample solution is allowed to be in contact with the electrode. | 2019-06-20 |
20190187084 | ELECTRODE ASSEMBLY FOR CONDUCTIVITY METER OR RESISTIVITY METER, CONDUCTIVITY METER AND RESISTIVITY METER USING THE SAME ELECTRODE ASSEMBLY - An electrode assembly for a conductivity meter or resistivity meter includes: an electrode main body; a test liquid intake flow path passing through the electrode main body; a pair of voltage electrodes which is respectively provided so that surfaces thereof are exposed to opposing inner wall surfaces forming the test liquid intake flow path; and a pair of current electrodes which is respectively provided so that surfaces thereof are exposed to each of the inner wall surfaces, and in this configuration, each of the pair of current electrodes contains a carbon-based material, and each of the surfaces of the pair of current electrodes exposed to the inner wall surfaces is in a strip shape. | 2019-06-20 |
20190187085 | Conductivity Sensor - The present disclosure relates to a sensor and a measuring system and a sensor network that incorporate one or more such sensors. An example sensor could be configured to measure a conductivity of a liquid. The sensor includes a first electrode and a second electrode, each electrode having a surface area, wherein the surface area of the electrodes determines a cell constant of the sensor (Kcell), and wherein at least one of the electrodes is provided with a switching means arranged so that the surface area of the respective electrode can be changed, thereby varying the cell constant (Kcell) of the sensor. | 2019-06-20 |
20190187086 | System and Method for Underground Wireless Sensor Communication - A system for collecting data associated with one or more sub-surface characteristics of a material is provided. The system may include a plurality of sensor nodes configured to collect data regarding the one or more sub-surface material characteristics and transmit the collected data to a data gateway. The data gateway may be configured to receive the collected data from the plurality of sensor nodes and store the collected data in memory. The system may also include a controller configured to receive the collected data from the data gateway via a network. The controller may be further configured to display data associated with the one or more sub-surface material characteristics. | 2019-06-20 |
20190187087 | SENSORS BASED ON NEGATIVE CAPACITANCE FIELD EFFECT TRANSISTORS - Chemical sensors and methods of forming and making the same include a semiconductor substrate having an input terminal and an output terminal. A negative capacitance structure is positioned on the semiconductor substrate and is configured to control a current passing from the input terminal to the output terminal. A functionalized electrode is in electrical contact with the negative capacitance structure and is configured to change surface potential in the presence of an analyte, such that a phase change in the negative capacitance structure is triggered when the surface potential exceeds a threshold. | 2019-06-20 |
20190187088 | REFERENCE ELECTRODE - A reference electrode is provided with an accommodation portion that is provided with a tube-shaped lead-out portion that can guide an accommodated internal liquid; a liquid junction portion that is connected to an end of the lead-out portion, and that allows the internal liquid to seep out; a liquid dripping portion that has a first end connected to the liquid junction portion, that has a second end that protrudes into the accommodation portion, and that guides the internal liquid to the liquid junction portion; and an internal electrode having at least a portion that is positioned further towards the first end side than the second end of the liquid dripping portion. | 2019-06-20 |
20190187089 | METHOD FOR OPERATING AN AMPEROMETRIC SENSOR, AMPEROMETRIC SENSOR, AND METHOD FOR MONITORING A MEASURING FLUID IN A FLUID LINE NETWORK - The present disclosure relates to a method for operating an amperometric sensor for detecting measured values of at least one first measurand that represents a concentration of a first analyte in a measuring fluid, and of at least one second measurand which represents a concentration of a second analyte different from the first analyte. The method includes steps of detecting measured values of the first measurand in a first operating mode of the amperometric sensor, switching the amperometric sensor to a second operating mode different from the first operating mode, and detecting measured values of the second measurand in the second operating mode of the amperometric sensor. The method can be used in monitoring the water quality in drinking water installations or drinking water networks. | 2019-06-20 |
20190187090 | Biosensor, Process for its Preparation and Method for Detecting an Analyte Using the Biosensor - A biosensor has the following components: a sensor base with an insulating substrate and at least one electrically conductive working electrode arranged thereon, in particular formed from separately controllable interdigital electrodes, reduced graphene applied to at least one working electrode, a spacer covalently bound to the reduced graphene, and an antibody fragment Fab covalently bound to the spacer. There is also described a process for producing the biosensor, a biochip equipped with the sensor and a method of detecting an analyte using the biosensor/biochip. | 2019-06-20 |
20190187091 | GLASS ELECTRODE - The present disclosure relates to a glass electrode including an analyte-sensitive glass membrane, an electrically conductive lead, and an intermediate layer which conductively connects the lead and the glass membrane to one another. According to the present disclosure, the intermediate layer is made of an electron- and/or ion-conducting polymer. | 2019-06-20 |
20190187092 | STACKED NANOFLUIDICS STRUCTURE - Methods and devices for a stacked nanofluidic sensor are described. The stacked nanofluidic sensor and methods for forming a nanosheet stack of at least two alternating layers of a first nanosheet material and a second nanosheet material on a substrate. Additionally, a gate structure is formed on the nanosheet stack. Further, nanofluidic channels are formed within the gate structure, including removing each layer of the first nanosheet material within the gate structure to form a channel configured to receive a nanofluidic sample. | 2019-06-20 |
20190187093 | CAPILLARY ELECTROPHORESIS CATHODE SYSTEMS AND METHODS - The present disclosure relates, in some embodiments, to a system for measuring capillary electrophoresis current. The system includes a plurality of capillaries ( | 2019-06-20 |
20190187094 | FORMATION OF LAYERS OF AMPHIPHILIC MOLECULES - To form a layer separating two volumes of aqueous solution, there is used an apparatus comprising elements defining a chamber, the elements including a body of non-conductive material having formed therein at least one recess opening into the chamber, the recess containing an electrode. A pre-treatment coating of a hydrophobic fluid is applied to the body across the recess. Aqueous solution, having amphiphilic molecules added thereto, is flowed across the body to cover the recess so that aqueous solution is introduced into the recess from the chamber and a layer of the amphiphilic molecules forms across the recess separating a volume of aqueous solution introduced into the recess from the remaining volume of aqueous solution. | 2019-06-20 |
20190187095 | ION MOBILITY SPECTROMETER WITH ION MODIFICATION - Ion modification An ion mobility spectrometer ( | 2019-06-20 |
20190187096 | METHOD AND APPARATUS FOR ANALYZING A SAMPLE BY HIGH-FIELD ASYMMETRIC WAVEFORM ION MOBILITY-MASS SPECTROMETRY - A method of analyzing a sample by high-field asymmetric waveform ion mobility-mass spectrometry (FAIMS-MS) is disclosed. An ion beam containing ions of a plurality N of isomers is directed into a FAIMS device. The compensation voltage (CV) at which the FAIMS device is operated is varied among a plurality M of values. For each of the M CV values, an intensity of the ion beam transmitted by the FAIMS device, or product ions derived therefrom, is measured at a mass-to charge ratio corresponding to the plurality N of isomers. The intensities of each of the plurality N of isomers is determined using a set of linear equations, relating the weighted measured intensity values at each value M of the CV and the intensities of each of the N isomers when the FAIMS device is in a non-separation condition. | 2019-06-20 |
20190187097 | SELF-ALIGNED NANOTIPS WITH TAPERED VERTICAL SIDEWALLS - A method of forming a semiconductor structure includes forming a substrate, forming an anchor layer, and forming one or more self-aligned nanotip pillar pairs disposed vertically between the substrate and the anchor layer. A given one of the nanotip pillar pairs comprises a bottom nanotip pillar and a top nanotip pillar, the bottom nanotip pillar comprising a base portion disposed on a top surface of the substrate and the top nanotip pillar comprising a base portion disposed in the anchor layer. The bottom nanotip pillar and the top nanotip pillar comprise sidewalls that taper to points as distance from the respective base portions increases. | 2019-06-20 |
20190187098 | THIN FILM BULK ACOUSTIC RESONATOR WITH SIGNAL ENHANCEMENT - Sensitivity of thin film bulk acoustic resonance (TFBAR) sensors is enhanced by mass amplification and operating a high frequency. | 2019-06-20 |
20190187099 | Acoustical Microscope - A system and method for using a microscope to aurally observe a specimen in a fluid is provided. In one embodiment of the present invention, the microscope is modified to include a first beam splitter, splitting a visual of the specimen magnified by the objective lens. A first beam is then provided to an audio frequency modulation sensing (AFMS) device, whose function is to sense photoacoustic modulation of the specimen and to extract aural data, allowing sound energy to be observed by a user (e.g., displayed on screen, played on a speaker, etc.). The second beam is provided to a second beam splitter, allowing visuals to be provided to the eyepiece and to at least one other sensor, where a second visual of the specimen is captured. The second visual can then be displayed on a screen in time synchronization with aural data provided by the AFMS device. | 2019-06-20 |
20190187100 | TOOL FOR NON-DESTRUCTIVE INSPECTION OF A FLAT PART - A tool enables non-destructive inspection of a flat part by ultrasonic transmission. The tool includes a clamp with a first arm pivotally coupled to a second arm about a pivot connection. An ultrasound transmitter is coupled to a first end of the first arm by a first ball joint connection, and an ultrasound receiver coupled to a first end of the second arm by a second ball joint connection. The transmitter has an active face for transmitting a sound signal that is received by an active face of the receiver. The active faces of the transmitter and the receiver are substantially at the same distance from the pivot connection. The tool further includes an alignment device that maintains the active faces of the transmitter and the receiver oriented towards each other and substantially parallel. | 2019-06-20 |
20190187101 | LAYERED STRUCTURE AND METHOD FOR FABRICATING SAME - Methods and techniques for fabricating layered structures, such as capacitive micromachined ultrasound transducers, as well as the structures themselves. The layered structure has a membrane that includes a polymer-based layer and a top electrode on the polymer-based layer. The membrane is suspended over a closed cavity and may be actuated by applying a voltage between the top electrode and a bottom electrode that may be positioned along or be a bottom of the closed cavity. The layered structure may be fabricated using a surface micromachining process. | 2019-06-20 |
20190187102 | LAYERED STRUCTURE AND METHOD FOR FABRICATING SAME - Methods and techniques for fabricating layered structures, such as capacitive micromachined ultrasound transducers, as well as the structures themselves. The layered structure has a membrane that includes a polymer-based layer and a top electrode on the polymer-based layer. The membrane is suspended over a closed cavity and may be actuated by applying a voltage between the top electrode and a bottom electrode that may be positioned along or be a bottom of the closed cavity. The layered structure may be fabricated using a wafer bonding process. | 2019-06-20 |
20190187103 | LASER ULTRASONIC TESTING - Laser ultrasonic testing includes a laser apparatus; a splitting unit that splits a pulsed laser from the laser apparatus into first and second lasers; a first pulse width conversion unit that converts a pulse width of the first laser; a first optical system that guides the first laser having the converted pulse width to a test object; a second pulse width conversion unit that converts a pulse width of the second laser; a pulse propagation time adjustment unit that adjusts a propagation time of the second laser having the converted pulse width; a second optical system that guides the second laser having the converted pulse width and adjusted propagation time to the test object; and a detection unit that detects a surface displacement change of the test object caused by an ultrasonic wave generated by the first laser when the second laser is reflected by the test object. | 2019-06-20 |
20190187104 | Omni-Directional Guided Wave Testing of Plate Structures Using Probe Having Rotating Guided Wave Sensor - A guided wave probe for use in guided wave testing of plate structures. The probe comprises a cup having a flat or nearly flat bottom, and a guided wave sensor, such as a magnetostrictive sensor, placed in the bottom of the cup. The sensor and/or cup are coupled to the plate structure, such that ultrasonic energy from the sensor is transmitted to the cup and the plate surface. The sensor is incrementally rotated in the cup, and sensor data is acquired at each incremental position. | 2019-06-20 |
20190187105 | SURFACE ACOUSTIC WAVE RFID SENSOR FOR CHEMICAL DETECTION AND (BIO MOLECULARDIAGNOSTICS - The present application describes embodiments of a radio-frequency identification (RFID) sensor based on a combinationof a surface acoustic wave (SAW) transducer and two-dimensional electron gas (2DEG) or two-dimensional hole gas (2DHG)conducting structure, and its use in chemical detection and (bio)molecular diagnostics. The SAW RFID sensor chip contains apiezoelectric substrate, on which a multilayer heterojunction structure is deposited. The heterojunction structure comprises atleast two layers, a buffer layer and a barrier layer, wherein both layers are grown from III-V single-crystalline or polycrystallinesemiconductor materials, such as Ga N/Al Ga N. Interdigitated transducers (IDTs) transducing SAWs are installed on top of thebarrier layer. A 2DEG or 2DHG conducting channel is formed at the interface between the buffer and barrier layers and provideselectron or hole current in the system between the non-ohmic (capacitively-coupled) source and drain contacts connected to theformed channel. | 2019-06-20 |
20190187106 | CONTINUOUS ULTRASONIC FAULT DETECTION - An ultrasonic mechanical defect and/or fault detection and monitoring system includes at least one ultrasonic fault detection device configured to measure ultrasonic emissions from an object under evaluation and to generate an output signal in response thereto. The system further includes at least one processor configured by code to receive the generated output signal; access a library of stored signal patterns; compare the generated output signal against the library of stored signal patterns; and generate an alert where the generated output signal matches at least one of the library of stored signal patterns. | 2019-06-20 |
20190187107 | METHODS FOR ULTRASONIC NON-DESTRUCTIVE TESTING USING ANALYTICAL REVERSE TIME MIGRATION - Systems and methods for nondestructive testing using ultrasound transducers, such as dry point contact (“DPC”) transducers or other transducers that emit horizontal shear waves, are described. An analytical reverse time migration (“RTM”) technique is implemented to generate images from data acquired using the ultrasound transducers. | 2019-06-20 |
20190187108 | REMOVAL OF POLAR COMPOUNDS FROM A GAS SAMPLE - A method of analyzing formation fluids includes introducing a fluid sample into a chromatograph system, passing the fluid sample through a pre-column including a polar column member and a apolar column member in a first flow direction, separating polar constituents from the fluid sample in the pre-column forming an analytical fluid, passing the analytical fluid through a main column of the chromatograph system, and analyzing the analytical fluid in the main column. | 2019-06-20 |
20190187109 | PURIFICATION ELEMENTS FOR DISPENSING A PURIFIED LIQUID - In various aspects provided are purification media and containers for dispensing a purified liquid are provided herein where a high surface area-to-volume chemically interactive purification media positioned at the outlet of a container that purifies the liquid as it is dispensed and/or extracted. | 2019-06-20 |
20190187110 | CHAMBERED SEPTUM - A septum contains at least one internal chamber along the central axis of the septum. The chamber provides relief space into which the sealing sections of the septum can deform as a needle passes through the septum. Incorporation of the chamber reduces surface area contact and friction between the septum and needle, which results in reduced septum tearing and reduced production of particulate matter from abrasion. | 2019-06-20 |
20190187111 | FLOW CONTROLLER AND GAS CHROMATOGRAPH EQUIPPED WITH THE SAME - A flow controller having high workability and a gas chromatograph equipped with the same are provided. A carrier gas controller is equipped with a flow path member. The flow path member is equipped with a first portion and a second portion extending horizontally from an upper end portion of the first portion. In the second portion, a gas outlet port is formed. An H | 2019-06-20 |
20190187112 | EMBEDDING SENSOR MODULE AND SENSING DEVICE - An embedding sensor module includes a cylinder and at least one flake sensor. A fluid tank is surrounded by the cylinder. The cylinder has a plurality of orifice connected to the fluid tank. The flake sensor is embedded in the fluid tank. | 2019-06-20 |
20190187113 | SYSTEM AND METHOD FOR AUTOMATICALLY ADJUSTING GAS SENSOR SETTINGS AND PARAMETERS - An automatic sensor excitation voltage adjustment feature, a multi-range concentration feature, a single calibration feature and a barrier circuit feature. The automatic sensor excitation voltage adjustment feature includes a transmitter having a transmitter microprocessor that provides an initial voltage to a sensor having a sensor microprocessor. As the voltage changes a correction signal is relayed from the sensor microprocessor to the transmitter microprocessor. The correction signal is used to adjust the voltage applied to the sensor. The multi-range concentration sensor feature includes an amplifier associated with the senior/micro-processor to create gain settings used to optimize sensor resolution by changing a gain value for the sensor. This enables use of a single sensor for a variety of different concentration ranges. The single calibration feature enables a sensor to be calibrated at a single gas concentration value, and thereafter be used for a variety of different concentration range applications. | 2019-06-20 |
20190187114 | CONTROL APPARATUS AND GAS DETECTION METHOD - A control apparatus mounted on a diesel vehicle including an oxidation catalyst, a selective reduction catalyst, and a gas sensor includes an activation determination section, a concentration computation section, and a deterioration determination section. The concentration computation section computes the concentration of flammable gas from a sensor output in a period during which the activation determination section determines that the oxidation catalyst is not in the activated state and computes the concentration of ammonia gas from the sensor output in a period during which the activation determination section determines that the oxidation catalyst is in the activated state. The deterioration determination section determines whether or not the oxidation catalyst has deteriorated, on the basis of the concentration of the flammable gas computed by the concentration computation section. | 2019-06-20 |
20190187115 | AIRCRAFT COCKPIT PORTABLE COMPONENT GAS SENSOR - A system includes a portable air sensing device and an electronic interface device. The portable air sensing device is configured to sense a concentration of component gas in surrounding air and wirelessly transmit the sensed concentration. The electronic interface device is positioned within a cockpit of an aircraft and is communicatively coupled with the portable air sensing device. The electronic interface device is configured to receive the wirelessly transmitted concentration from the portable air sensing device, and generate, for display, an indication of the received concentration in relation to a defined threshold maximum concentration of the component gas. | 2019-06-20 |
20190187116 | SYSTEMS AND METHODS FOR DETECTING A NEUTRON GENERATOR OPERATING IN AIR - A system that may identify when a pulsed neutron generator is operating while disposed in an undesirable environment, such as in air, may include a pulsed neutron generator designed to emit neutrons in an environment. The system may also include a radiation detector designed to take measurements of the neutrons. The system may also include data processing circuitry designed to determine if the environment surrounding the pulsed neutron generator is air based at least in part on a neutron signal obtained by the radiation detector. The determination may include comparing one or more characteristics of the neutron signal with corresponding reference characteristics. | 2019-06-20 |
20190187117 | FACILE METHODS TO DETECT TOXIN IN SEAFOOD - Methods and systems for detecting environmental contaminants is described. In an embodiment, a method includes macerating and extracting a sample; reacting a first polymerizable compound with the sample to form a second mixture comprising a second polymerizable compound; adding an initiator to the second mixture comprising the second polymerizable compound; performing a polymerization reaction on the second mixture comprising the second polymerizable compound to form a third mixture comprising a precipitate; and performing a turbidimetric analysis on the third mixture comprising the precipitate. In another embodiment, a method includes macerating and extracting a sample; reacting a first mixture comprising the functionalized polythiophene compound and the sample to form a second mixture comprising a second functionalized polythiophene compound; performing a colorimetric analysis on the second mixture comprising the second functionalized polythiophene compound. | 2019-06-20 |
20190187118 | OPTICAL SENSOR - The present disclosure relates to an optical sensor comprising at least one light source for emitting transmission light into a medium, at least one detector, wherein the transmission light is at least partially converted in the medium by fluorescence into fluorescent light and the detector receives the fluorescent light, wherein a first receiver signal can be generated from the fluorescent light, and wherein a first measured value can be determined from the first receiver signal, wherein the transmission light is at least partially scattered by means of the medium to form scattered light, and the detector receives the scattered light, wherein a second receiver signal can be generated from the scattered light, and wherein a second measured value can be determined from the second receiver signal. The present disclosure further relates to a method for determining a first and second measured value of a medium. | 2019-06-20 |
20190187119 | DETERMINATION OF TOTAL BASE NUMBER IN LUBRICANTS - Systems and methods are provided for estimating the total base number of used oil in an engine. The systems and methods can involve characterizing the sulfur content and at least one other element content of the oil both before introduction into the engine and after passing through an engine cylinder during combustion. Depending on the aspect, a total base number of the oil prior to use can also be measured, or the total base number before use can be estimated based on the at least one element content. | 2019-06-20 |
20190187120 | SOLVENCY FOR ASPHALTENE DEPOSIT REMEDIATION OR INHIBITION - Methods for estimating the solvency potential for various chemical additives used for asphaltene deposit remediation or inhibition have been developed. These methods can be used for remediating or inhibiting asphaltene deposition in various applications including upstream production (e.g., near-wellbore, downhole, flow-lines, separators), midstream processes (e.g., pipe lines, transport, and storage), and downstream (e.g., hydrocarbon refining). | 2019-06-20 |
20190187121 | DETERMINING HYDROCARBON CONTENT IN STEAM CONDENSATE - Systems and methods are provided for determining a content of a hydrocarbon or other compound, such as a C | 2019-06-20 |
20190187122 | METHOD AND APPARATUS FOR DETECTING A BEARING LUBRICATION FAILURE - A bearing lubrication system includes a lubricant distributor configured to perform a lubrication operation by moving lubricant toward an interior of a housing of a bearing, at least one sensor configured to measure at least one condition of the bearing and to produce a signal indicative of the at least one measured condition and a controller configured to produce a transient detection signal, a signal indicative of a second derivative of the measurement signal, for example, and to determine whether an absolute value of the transient detection signal exceeds a threshold value during a given time period after the lubrication operation and to output a failure signal indicative of a lubrication failure in response to a determination that the absolute value of the transient detection signal does not exceed the threshold value during the given time period. Also a method of operating a bearing lubrication system. | 2019-06-20 |
20190187123 | NANOFLUIDIC DEVICES WITH INTEGRATED COMPONENTS FOR THE CONTROLLED CAPTURE, TRAPPING, AND TRANSPORT OF MACROMOLECULES AND RELATED METHODS OF ANALYSIS - Devices for controlling the capture, trapping, and transport of macromolecules include at least one fluidic transport nanochannel that intersects and is in fluid communication with at least one transverse nanochannel with (shallow) regions and/or with integrated transverse electrodes that enable fine control of molecule transport dynamics and facilitates analyses of interest, e.g., molecular identification, length determination, localized (probe) mapping and the like. | 2019-06-20 |
20190187124 | TEST PAPER BOX AND INTELLIGENT TOILET CONTAINING SAME - A test paper box and a smart toilet containing same are provided. The test paper box has a support and a housing arranged at the outside of the support. The support has a base and an elongated cavity arranged at the base for storing test paper. The base is provided with a through hole arranged at a location corresponding to a bottom surface of the elongated cavity. A paper-receiving slot is arranged below the through hole. The paper-receiving slot is fixed to the bottom of the base to receive the bottommost piece of test paper exposed from the elongated cavity, and the paper-receiving slot is provided with a paper outlet. The test paper box can be attached and detached conveniently, delivers test paper smoothly, can be replaced easily, has low costs, and is suitable for smart toilets. | 2019-06-20 |
20190187125 | MEASUREMENT METHOD - A specimen containing blood is divided into a first specimen and a second specimen. The blood in the second specimen is hemolyzed. The first specimen containing a substance to be measured is introduced into an accommodating unit and a measurement value indicating an amount of the substance to be measured in the first specimen in a state in which the blood is not hemolyzed is acquired. In a state in which the second specimen in a state in which the blood is hemolyzed is present in the accommodating unit of a measurement chip, second light acquired when first light including light of a wavelength absorbed by a red blood cell passes through the second specimen in the accommodating unit is detected. On the basis of a detection result of the second light, a hematocrit value of the specimen is determined. The measurement value is corrected on the basis of the hematocrit value. | 2019-06-20 |
20190187126 | DEVICE FOR RAPID DETECTION OF TUBERCULOSIS-LIPOARABINOMANNAN (TB-LAM) WITH ENHANCED SENSITIVITY - A device for rapid detection of a tuberculosis lipoarabinomannan (TB-LAM) is provided. The device includes a pre-concentrator unit for concentrating the TB-LAM comprising: an ion-exchange medium comprising one or more ligands configured to capture the TB-LAM from the source biological sample, wherein the captured-TB-LAM is eluted from the ion-exchange medium as an eluate comprising a concentrated form of TB-LAM; a cassette; a lateral flow assay unit disposed in the cassette; and an integration unit attached to the pre-concentrator unit and the cassette. The integration unit is configured to operatively couple and de-couple the pre-concentrator unit and the cassette. The pre-concentrator unit and the lateral flow assay unit disposed in the cassette are in a fluidic communication in a coupled form. The device for rapid detection of TB-LAM further comprises a dilutor unit. | 2019-06-20 |
20190187127 | IN VITRO NEONATAL BIOMIMETIC (NMIMIC) MODEL AND METHODS OF USING SAME - In vitro biomimetic models of the neonatal immune system are provided along with methods of using the models in pre-clinical assessment of infant immune cell-mediated and humoral responses to immunogenic stimulation, such as vaccination. The models include one comprising cord blood-derived T follicular helper cells and B cells, and one comprising cord blood-derived dendritic cells and CD4+ T cells. The models can be used, for example, to assess candidate vaccines via analysis of cellular responses to antigen and vaccine exposure. | 2019-06-20 |
20190187128 | SCREEN PRINTING TISSUE MODELS - A process of simply, cheaply, and reproducibly creating complex tissue models using screen printing and the tissue model prepared using the screen printing process. These models are amenable to high throughput screening. They will allow the study of components of disease progression and can be used for screening therapies. | 2019-06-20 |
20190187129 | CANCER MODELING PLATFORMS AND METHODS OF USING THE SAME - Described herein are in vitro cell constructs (or “organoids”) useful as a tumor model, the constructs comprising live tumor cells from a subject. In some embodiments, provided are in vitro cell constructs comprising: (a) a core comprised of live tumor cells; and (b) a shell surrounding (e.g., encapsulating) the core, the shell comprised of live benign cells (e.g., tissue cells, benign or differentiated tumor cells, etc.). Also described herein are methods of making and using such constructs. Further provided are devices useful for evaluating tumor cells in vitro, comprising: (a) a microfluidic device having a chamber, and a channel in fluid communication with the chamber; (b) a live tumor cell construct (e.g., an organoid) in the chamber; (c) a growth media in the chamber and the channel; (d) a pump operatively associated with the chamber and channel and configured for circulating the media from the chamber through the channel and back to the chamber; (e) a microporous membrane (e.g., a TRANSWELL® microporous membrane) in the channel and positioned so that the media flows therethrough. | 2019-06-20 |
20190187130 | COLORS FOR CHROMOGENIC IHC AND ISH STAINING WITH MULTI-DYE QUINONE METHIDE AND TYRAMIDE CONJUGATES - Disclosed herein are novel chromogenic conjugates, the conjugates comprising at least two detectable moieties. | 2019-06-20 |
20190187131 | UNMASKING ENDOTOXINS IN SOLUTION - The invention relates to unmasking endotoxins in compositions so that previously present, but undetectable endotoxins are rendered detectable. | 2019-06-20 |
20190187132 | Antigen detection of Trichinella - can be detected in a tissue extract sample. A suitable kit includes (a) a detection carrier containing a first antibody against one or more antigens of | 2019-06-20 |
20190187133 | DIAGNOSTIC REAGENT KIT FOR DETECTING CHRONIC BRAIN PATHOLOGIES OF ISCHEMIC GENESIS - The invention relates to diagnostics, namely to a reagent kit, a rapid method and a device for detecting the fact of chronic, ischemia-linked brain pathology. A special feature of the invention is the use of an immunoactive hybrid peptide produced as a product of two fragments of the NMDA neuroreceptor subunits. A device is described that allows quick and convenient testing of autoantibodies in the patient's blood that recognize the hybrid peptide. The method of detection of autoantibodies is based on the principle of lateral flow immunochromatography. The invention can be used for prophylactic medical examination (screening of chronic ischemia-linked brain lesions), to detect decompensated chronic cerebral ischemia at the prehospital stage by general practitioners or neurologists, as well as in neurosurgery and sports medicine for diagnostics of delayed cerebral ischemia in persons with craniocerebral injury. | 2019-06-20 |
20190187134 | SOLID-PHASE CARRIER CAPABLE OF IMPROVING DETECTION SENSITIVITY, AND DETECTION COMPONENT - Provided is a solid phase carrier capable of improving detection sensitivity, and a detection device. The solid phase carrier is provided with a polydimethylsiloxane layer with an initiator on the surface, and titanium dioxide particles distributed in said polydimethylsiloxane layer with an initiator on the surface. | 2019-06-20 |
20190187135 | GAS SENSOR USING METAL NANOPARTICLES - A gas sensor includes a substrate, a pair of electrodes formed on the substrate, having a nanogap formed therebetween, and facing each other, and metal nanoparticles present in the nanogap, wherein a ligand organic single-molecule having a gas-bonding functional group and a ligand organic single-molecule having a substrate-bonding functional group are disposed on the surface of the metal nanoparticles, and wherein an organic single-molecule having a substrate-functional group bonding to the substrate-bonding functional group of the ligand organic single-molecule having a substrate-bonding functional group disposed on the surface of the metal nanoparticles is immobilized to the substrate, a method for manufacturing the gas sensor, and a use thereof. | 2019-06-20 |
20190187136 | METHODS OF ENUMERATING PARTICLES PRESENT IN A CELL COMPOSITION - Provided herein are methods of assessing or determining the presence or absence of particles, such as bead particles, present in a cell composition. Also provided are articles of manufacture and kits for use in the methods. | 2019-06-20 |
20190187137 | AU MULTICOMPONENT NANOMATERIALS AND SYNTHESIS METHODS - Compositions which comprise a gold nanoparticle, dithiolated diethylenetriamine pentaacetic acid (DTDTPA), and a thioctic acid terminated peptide, wherein the DTDTPA is directly linked to the gold nanoparticle surface via an Au—S bond, and wherein the thioctic acid terminated peptide is directly linked to the gold nanoparticle surface via an Au—S bond. | 2019-06-20 |
20190187138 | SYSTEM FOR DETECTING CONCENTRATION OF AN ANALYTE BIOMOLECULE IN A SAMPLE AND METHOD THEREOF - Various embodiments of the methods and systems disclosed herein provide a detection system that detects concentration of an analyte biomolecule (e.g., a protein, a biomarker, etc.) in a sample (e.g., a blood sample) to diagnose a disease. The detection system includes one or more micro-cantilevers that are immobilized with one or more receptor biomolecules to detect a concentration of an analyte biomolecule in the sample. The detection system further compares the concentration of the analyte biomolecule with a threshold value for diagnosing a disease. | 2019-06-20 |
20190187139 | MODULAR ASSAY READER DEVICE - Certain aspects relate to systems and usage techniques for modular lateral flow assay reader devices that can receive a number of different modules having a barcode scanning input device and optional network connectivity capabilities. A barcode scanning module can provide a simple input method that reduces errors compared to manual data entry. A network connectivity module can enable transmission of test results over a public network for standardizing, tracking and electronically connecting test results from assay reader devices located throughout a network. Such devices can programmatically implement a simplified workflow whereby pressing a single button readies the device for imaging, analyzing, and data storage/transmission and, in some implementations, configures the device to operate in one of a plurality of device operation modes. | 2019-06-20 |
20190187140 | HYDROGEL PLATFORM FOR AQUEOUS TWO-PHASE CONCENTRATION OF A TARGET TO ENHANCE ITS DETECTION - It was discovered that hydrogel scaffolds can be used to induce phase separation as aqueous two-phase systems (ATPSs) pass through and/or rehydrate the scaffolds, allowing for concentration of target analyte(s) (e.g., biomolecule(s)) into a particular phase of the ATPS or into a leading front. Accordingly, in various embodiments methods and devices are provided that utilize aqueous two-phase systems and hydrogel scaffolds to improve the sensitivity of assays (e.g., of point-of-care assays) without sacrificing cost or ease of use. | 2019-06-20 |