24th week of 2012 patent applcation highlights part 46 |
Patent application number | Title | Published |
20120149047 | METHOD FOR QUANTITATIVELY DETERMINING LDL CHOLESTEROLS - A method for quantitatively determining LDL cholesterol, including the steps of adding to serum a surfactant selected from among polyoxyethylenealkylene phenyl ethers and polyoxyethylenealkylene tribenzylphenyl ethers and a cholesterol-assaying enzyme reagent so as to preferentially react cholestrols in high density- and very low density-cholesterols among lipoproteins, and subsequently determining the amount of cholesterol that reacts thereafter. This method can eliminate the necessity for pretreatments such as centrifugation and electrophoresis, enables the quantitative determination to be conducted in an efficient, simple manner, and can be applied to various automatic analyzers. | 2012-06-14 |
20120149048 | METHOD OF DIFFERENTIATING BETWEEN BLOOD AND CONTROL SOLUTIONS CONTAINING A COMMON ANALYTE - Glucose measured in blood samples is distinguished from glucose measured in the control solutions used to test the optical instruments which make such measurements. The control solutions contain a labeling substance recognized by the optical instrument to distinguish glucose measurements made of control solutions from those made of blood samples. | 2012-06-14 |
20120149049 | SYSTEM AND METHOD FOR PRESENTING AN AUTOMATED ASSESSMENT OF A SAMPLE'S RESPONSE TO EXTERNAL INFLUENCES - A biological sample is evaluated by an automated apparatus that operates to identify one or more areas of interest within the sample. Each area of interest has a classifiable appearance brought about from the sample's interaction with an external influence under investigation. The apparatus classifies each area of interest by automatically resolving and identifying either the existence of an abnormal feature in that area of interest or a lack of any abnormality in that area of interest. An abnormal feature qualified as differentiable from a control reference unaffected by the external influence by at least one of: shape; area; size; and proximity to other resolved features within the area of interest. The apparatus counts incidences of abnormal features within each area of interest and automatically presents an assessment of the effect of the external influence on the sample based at least in part on the count of abnormal features. | 2012-06-14 |
20120149050 | AUTOMATED SYSTEMS AND METHODS FOR PREPARING BIOLOGICAL SPECIMENS FOR EXAMINATION - The systems and methods disclosed herein permit automated preparation of biological specimens for examination. The disclosed systems and methods provide fast, efficient, and highly uniform specimen processing using minimal quantities of fluids. The methods include at least a fixing phase for fixing a biological specimen to a substrate such as a microscope slide, a staining phase for staining the specimen, and a rinsing phase for rinsing the specimen. One or more of the fixing, staining, and rinsing phases include one or more agitation cycles for distributing reagents evenly and uniformly across the specimen. The systems can be implemented as a standalone device or as a component in a larger system for preparing and examining biological specimens. | 2012-06-14 |
20120149051 | DEVICES FOR THE PRODUCTION OF CELL CLUSTERS OF DEFINED CELL NUMBERS AND CLUSTER SIZES - Devices for the in vitro aggregation of cells. The devices are characterized by containing special ground cavities allowing cluster formation to take place when a cell suspension is seeded onto the device. Further, the present invention relates to a method for aggregating cells and the use of the devices of the present invention for the aggregation of cells. | 2012-06-14 |
20120149052 | METHOD FOR OPTICAL MEASURING VARIATIONS OF CELL MEMBRANE CONDUCTANCE - The instant invention refers to an optical method to extrapolate cell membrane conductance by indirect measurement of changes in transmembrane voltage, upon exposure of a cell sample to electric current pulses. The method is advantageously used for evaluating the activity of molecules able to alter, directly or indirectly, membrane permeability. A specific field of application is the screening of candidate compounds putatively acting on ion channel activity. In particular, it is open to the study of all ion channels with no limitations on the mechanisms of activation or to the ion species involved. The method is also advantageously used for evaluating a cell status, namely a differentiative or a pathologic status. | 2012-06-14 |
20120149053 | CARRIER PEPTIDE FRAGMENT AND USE THEREOF - A method for transferring a foreign substance includes the steps of: preparing a construct for transferring a foreign substance that contains a carrier peptide fragment including any amino acid sequence selected from SEQ ID Nos. 1, 2, 3, 4, 5, and 6, or an amino acid sequence formed by the substitution, deletion, and/or addition (insertion) of 1, 2, or 3 amino acid residues in the amino acid sequence of the selected sequence identification number, and a foreign substance of interest that is bonded to the N-terminus and/or C-terminus of the carrier peptide fragment; supplying the construct for transferring a foreign substance to a test sample that contains a target eukaryotic cell; and incubating the test sample that has been supplied with the construct for transferring a foreign substance to thereby transfer the construct into the eukaryotic cell in the test sample. | 2012-06-14 |
20120149054 | MEASUREMENT METHOD FOR VIABLE CELL COUNT, AND CULTURE MEDIUM - There are provided a method of identifying the | 2012-06-14 |
20120149055 | PAPER STRIP FOR DETERMINING MINIMUM INHIBITORY CONCENTRATIONS OF ANTIBIOTICS - The present invention concerns the sector of chemical, clinical, bacteriological and immunological analyses and more specifically it concerns the use of a strip of impregnated paper in order to determine, in the simplest, most economical and most accurate way, the correct Minimum Inhibitory Concentration (M.I.C.) of antibiotic molecules to be administered to patients as claimed in patent No. EP 0 157 071. | 2012-06-14 |
20120149056 | METHOD AND REAGENTS FOR DETECTING THE PRESENCE OR ABSENCE OF A TARGET SUBSTANCE IN A TEST SAMPLE - Reagent mixtures and testing procedures for detecting the presence or absence of various target substances such as aureus; vancomycin-resistant enterrococcus; Group B | 2012-06-14 |
20120149057 | METHOD FOR PROGNOSING RESPONSE TO CANCER THERAPY WITH 5, 10, 15, 20-TETRAKIS (CARBOXYPHENYL) PORPHINE - Presented is a method of prognosing a patient's response to a cancer therapy wherein prior to the therapy contacting a sample of cells from the patient's tissue or organ being treated for the cancer with a solution of TCPP to permit binding of the TCPP to components of the abnormal dysplastic or carcinomic cells, if any are present; detecting TCPP fluorescence in the sample, the presence of TCPP fluorescence being indicative that the sample contains dysplastic or carcinomic cells; at intervals during the therapy and subsequent to the therapy performing steps a-c on another sample of cells from the patient's tissue or organ being treated for the cancer; and determining if the percentage of abnormal pre-cancerous cells in the samples tested during and subsequent to the therapy are reduced as compared with the sample tested prior to the therapy, the reduction being prognostic of the patients response to the cancer therapy. | 2012-06-14 |
20120149058 | PROCESS AND APPARATUS FOR TESTING SUBSTANCES FOR POTENTIAL CARCINOGENICITY - An apparatus ( | 2012-06-14 |
20120149059 | TISSUE PROCESSOR - A tissue processing system includes a plurality of processing stations. Each processing station includes a plurality of tissue receiving areas that are each configured to accommodate a tissue sample as well as physically isolate that tissue sample from other tissue samples at other receiving areas of the same processing station. Each processing station is configured to separately and individually process the tissue sample at each receiving area to either reduce or eliminate any potential for cross-contamination between the tissue samples undergoing processing at the same processing station. For each receiving area of each processing station, the system is configured to immerse a tissue sample at a particular receiving area in processing fluid for a pre-determined time according to a pre-defined protocol that is based upon parameters of that tissue sample. | 2012-06-14 |
20120149060 | Nucleic Acids for Cloning and Expressing Multiprotein Complexes - The present invention relates to a nucleic acid containing at least one homing endonuclease site (HE) and at least one restriction enzyme site (X) wherein the HE and X sites are selected such that HE and X result in compatible cohesive ends when cut by the homing endonuclease and restriction enzyme, respectively, and the ligation product of HE and X cohesive ends can neither be cleaved by the homing endonuclease nor by the restriction enzyme. Further subject-matter of the present invention relates to a vector comprising the nucleic acid of the present invention, host cells containing the nucleic acid and/or the vector, a kit for cloning and/or expression of multiprotein complexes making use of the vector and the host cells, a method for producing a vector containing multiple expression cassettes, and a method for producing multiprotein complexes. The invention also relates to a methods of assembling multiple single vectors (“vector entities”) into fusion vectors and to method of disassembling a fusion vector containing multiple of such vector entities into single vectors. The invention is also directed to fusion vectors containing multiple vector entities. | 2012-06-14 |
20120149061 | Modified Antibody Compositions, Methods of Making and Using Thereof - The present disclosure provides modified antibodies which contain an antibody or antibody fragment (AB) modified with a masking moiety (MM). Such modified antibodies can be further coupled to a cleavable moiety (CM), resulting in activatable antibodies (AAs), wherein the CM is capable of being cleaved, reduced, photolysed, or otherwise modified. AAs can exhibit an activatable conformation such that the AB is more accessible to a target after, for example, removal of the MM by cleavage, reduction, or photolysis of the CM in the presence of an agent capable of cleaving, reducing, or photolysing the CM. The disclosure further provides methods of making and using such modified antibodies and activatable antibodies. | 2012-06-14 |
20120149062 | High Purity Lipopeptides - The invention discloses highly purified daptomycin and to pharmaceutical compositions comprising this compound. The invention discloses a method of purifying daptomycin comprising the sequential steps of anion exchange chromatography, hydrophobic interaction chromatography and anion exchange chromatography. The invention also discloses a method of purifying daptomycin by modified buffer enhanced anion exchange chromatography. The invention also discloses an improved method for producing daptomycin by fermentation of | 2012-06-14 |
20120149063 | PROCESS FOR THE CULTURING OF CELLS - The invention relates to a process for the culturing of cells, preferably E1-immortalized HER cells, more preferably PER.C6 cells in a reactor in suspension in a cell culture medium, wherein the cells produce a biological substance, preferably an antibody, wherein at least one cell culture medium component is fed to the cell culture and wherein the cell culture comprising the cells, the biological substance and cell culture medium is circulated over a separation system and wherein the separation system separates the biological substance from substances having a lower molecular weight than the biological substance and wherein the biological substance is retained in or fed back into the reactor. Preferably part of the substances of lower molecular weight is continuously removed from the cell culture. | 2012-06-14 |
20120149064 | Filamentous Fungi With Impaired PTRB Activity For Altered Protein Production - A filamentous fungal cell is provided comprising at least one mutation, wherein the filamentous fungal cell has impaired ptrB activity and has altered expression of a protein of interest as compared to a corresponding parent filamentous fungal cell. In one embodiment, the altered expression of the protein of interest is enhanced expression of the protein of interest. | 2012-06-14 |
20120149065 | USE OF MANGANESE PEROXIDASE FOR ENZYMATIC HYDROLYSIS OF LIGNOCELLULOSIC MATERIAL - Improved manganese peroxidases, polynucleotides encoding improved manganese peroxidase and vectors and cells thereof are provided, as well as methods for converting a cellulose-containing biomass feedstock to ethanol using improved manganese peroxidases and cells expressing a heterologous manganese peroxidase as disclosed herein. | 2012-06-14 |
20120149066 | Method for Producing Glucosamine by Culturing Microorganism with Low-cost Medium - A method for producing glucosamine with microorganism comprises of fermenting with a microorganism selected from the group consisting of | 2012-06-14 |
20120149067 | Methods for producing hyaluronan in a recombinant host cell - The present invention relates to methods for producing a hyaluronic acid, comprising: (a) cultivating a | 2012-06-14 |
20120149068 | METHODS AND COMPOSITIONS FOR AMPLIFICATION OF RNA SEQUENCES - The invention provides methods for isothermal amplification of RNA. The methods are particularly suitable for amplifying a plurality of RNA species in a sample. The methods employ a composite primer, a second primer and strand displacement to generate multiple copies of DNA products comprising sequences complementary to an RNA sequence of interest. In another aspect, the methods employ a single primer (which is a composite primer) and strand displacement to generate multiple copies of DNA products comprising sequences complementary to an RNA sequence of interest. In some embodiments, a transcription step is included to generate multiple copies of sense RNA of an RNA sequence of interest. The methods are useful for preparation of nucleic acid libraries and substrates for analysis of gene expression of cells in biological samples. The invention also provides compositions and kits for practicing the amplification methods, as well as methods which use the amplification products. | 2012-06-14 |
20120149069 | METHODS AND COMPOSITIONS FOR SEAMLESS CLONING OF NUCLEIC ACID MOLECULES - The present invention is in the fields of biotechnology and molecular biology. More particularly, the present invention relates to cloning or subcloning one or more nucleic acid molecules comprising one or more type IIs restriction enzyme recognition sites. The present invention also embodies cloning such nucleic acid molecules using recombinational cloning methods such as those employing recombination sites and recombination proteins. The present invention also relates to nucleic acid molecules (including RNA and iRNA), as well as proteins, expressed from host cells produced using the methods of the present invention. | 2012-06-14 |
20120149070 | VARIANTS OF GLUCOAMYLASE - The present invention relates to combinatorial variants of a parent glucoamylase that have altered properties for reducing the synthesis of condensation products during hydrolysis of starch. Accordingly the variants of a parent glucoamylase are suitable such as for use within brewing and glucose syrup production. Also disclosed are DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells. | 2012-06-14 |
20120149071 | D-AMINOACYLASE - A D-aminoacylase having a high substrate specificity is provided. This D-aminoacylase can produce D-amino acids from N-acetyl-D,L-amino acids conveniently and efficiently at a low cost. | 2012-06-14 |
20120149072 | METHOD FOR PRODUCING BASIC SUBSTANCE - A method for producing a basic substance by fermentation comprising culturing a microorganism having an ability to produce the basic substance in a liquid medium contained in a fermentation tank to produce and accumulate the basic substance in the medium, wherein amount of sulfate and/or chloride ions used as counter ions of the basic substance is reduced by adjusting total ammonia concentration in the medium to be within a specific concentration range during at least a part of the total period of culture process. | 2012-06-14 |
20120149073 | Ketoreductase Polypeptides for the Preparation of Phenylephrine - The disclosure relates to engineered ketoreductase polypeptides and processes of using the polypeptides for production of phenylephrine. | 2012-06-14 |
20120149074 | Transformant Comprising Gene Coding for ws/dgat and Method of Producing Fatty Acid Ethyl Esters Using the Same - The present invention relates to a transformant comprising a gene encoding ws/dgat (wax ester synthase/acyl-coenzyme A: diacylglycerol acyltransferase) and a method of producing fatty acid ethyl esters using the same. Specifically, the transformant for producing fatty acid ethyl esters is constructed such that glycerol is used as a fermentation substrate, and comprises an atfA gene encoding ws/dgat (wax ester synthase/acyl-coenzyme A: diacylglycerol acyltransferase) from | 2012-06-14 |
20120149075 | SOAPS PRODUCED FROM OIL-BEARING MICROBIAL BIOMASS AND OILS - Soap and cosmetic products can be made from oil-bearing microbial biomass via the alkaline hydrolysis of glycerolipids and fatty acid esters to fatty acid salts. The saponified microbial oils/lipids can be combined with a variety of additives to produce compositions for use as soaps and other cosmetic products, which may also contain other constituents of the biomass, including unsaponified oils, glycerol and carotenoids, among others. | 2012-06-14 |
20120149076 | INTEGRATION OF FERMENTAITON WITH MEMBRANE - Herein disclosed is a method comprising a) fermenting biomass to produce a fermentation broth; b) separating the fermentation broth into a liquid stream and a solid or slurry stream; c) passing the liquid stream through a reverse osmosis membrane to obtain a permeate and a retentate; and d) concentrating the retentate. Herein disclosed is a method comprising a) fermenting biomass in a first fermentor to produce a first fermentation broth; b) separating the first fermentation broth into a first liquid stream and a first solid or slurry stream; c) introducing the first solid or slurry stream into a second fermentor to produce a second fermentation broth, wherein the second fermentor comprises a lower fermentation products concentration than the first fermentor; d) separating the second fermentation broth into a second liquid stream and a second solid or slurry stream; and e) passing the second liquid stream through a reverse osmosis membrane. | 2012-06-14 |
20120149077 | Mesophilic and Thermophilic Organisms Modified to Produce Acrylate, and Methods of Use Thereof - The present invention provides for novel metabolic pathways leading to acrylate formation in a consolidated bio-processing system (CBP) where lignocellulosic biomass is efficiently converted to acrylate. In one such metabolic pathway, pyruvate is converted to lactate, which is converted to lactoyol-CoA, which is converted to acryloyl-CoA, and which is finally converted to acrylate. In another such metabolic pathway, pyruvate is converted to L-α-alanine, which is converted to L-aspartate, which is converted to β-alanine, which is converted to β-alanyl-CoA, which is converted to acryloyl-CoA, and which is finally converted to acrylate. In yet another metabolic pathway, pyruvate is converted to lactate, and then lactate is converted directly to acrylate. In certain aspects, the invention provides for heterologous expression of one or more enzymes in a mesophilic or thermophilic organism, such as | 2012-06-14 |
20120149078 | Polypeptides Having Acetylxylan Esterase Activity And Polynucleotides Encoding Same - The present invention relates to isolated polypeptides having acetylxylan esterase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. | 2012-06-14 |
20120149079 | Polypeptides Having C4 Dicarboxylic Acid Transporter Activity and Polynucleotides Encoding Same - The present invention relates to isolated polypeptides having C4-dicarboxylic acid transporter activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, and methods of producing C4-dicarboxylic acids, such as malic acid. | 2012-06-14 |
20120149080 | YEAST PRODUCTION CULTURE FOR THE PRODUCTION OF BUTANOL - High cell density cultures of yeast were found to have higher tolerance for butanol in the medium. The high cell density yeast cultures had greater survival and higher glucose utilization than cultures with low cell densities. Production of butanol using yeast in high cell density cultures is thus beneficial for improving butanol production. | 2012-06-14 |
20120149081 | METHOD FOR FERMENTATION CULTURE IN MEDIUM CONTAINING XYLOSE - The xylose-metabolizing ability and particularly the xylose incorporation rate, of yeast to which xylose-metabolizing ability has been imparted are significantly improved. The method according to the present invention comprises the steps of: culturing yeast having xylose-metabolizing ability in a xylose-containing medium in which the concentration of at least one amino acid selected from the group consisting of asparagine (Asn), serine (Ser), tyrosine (Tyr), threonine (Thr), and histidine (His) is increased; and recovering alcohol from the medium. | 2012-06-14 |
20120149082 | Method For The Preparation Of Cross-Linked Enzyme Aggregates With Improved Properties - The invention relates to a method for the preparation of hybrid cross-linked enzyme-silica aggregates including the steps of taking up enzyme molecules in a solvent, precipitating the enzyme molecules using a precipitation agent, and adding an alkoxysilane and crosslinking the mixture of alkoxysilane and precipitated enzyme aggregates, using a crosslinking agent comprising an aldehyde, to obtain hybrid crosslinked enzyme-silica aggregates. | 2012-06-14 |
20120149083 | PEG-Urate Oxidase Conjugates and Use Thereof - A naturally occurring or recombinant urate oxidase (uricase) covalently coupled to poly(ethylene glycol) or poly(ethylene oxide) (both referred to as PEG), wherein an average of 2 to 10 strands of PEG are conjugated to each uricase subunit and the PEG has an average molecular weight between about 5 kDa and 100 kDa. The resulting PEG-uricase conjugates are substantially non-immunogenic and retain at least 75% of the uricolytic activity of the unmodified enzyme. | 2012-06-14 |
20120149084 | FUSION PROTEINS - The invention provides a single chain, polypeptide fusion protein, comprising: a non-cytotoxic protease, or a fragment thereof, which protease or protease fragment is capable of cleaving a protein of the exocytic fusion apparatus of a target cell; a Targeting Moiety that is capable of binding to a Binding Site on the target cell, which Binding Site is capable of undergoing endocytosis to be incorporated into an endocome within the target cell; a protease cleaving site at which site the fusion protein is cleavable by the protease, wherein the protease cleavage site is located between the non-cytotoxic protease or fragment thereof and the Targeting Moiety; and the translocation domain that is capable of translocating the protease or protease fragment from within an endosome, across the endosomal membrane and into the cytosol of the target cell. | 2012-06-14 |
20120149085 | FUSION PROTEINS CONTAINING RECOMBINANT CYTOTOXIC RNASES - Recombinant immunotoxins containing a cytotoxic RNAse fused to an antibody or antibody fragment may be produced in mammalian cell culture. Surprisingly, immunotoxins containing a cytotoxic RNAse fused to the N-terminus of one antibody variable domain can be prepared and retain the ability to specifically bind antigen. The immunotoxins may be used in a variety of therapeutic methods for treating diseases or syndromes associated with unwanted or inappropriate cell proliferation or activation. | 2012-06-14 |
20120149086 | Cutinase-Producing Genetically Engineered Microorganism and Use Thereof - The present invention relates to the field of bioengineering and discloses a cutinase-producing genetically engineered microorganism and use thereof. Recombinant plasmid Tfu_0883-hlyAs/pET20b(+) was constructed and transformed into | 2012-06-14 |
20120149087 | GLUCOAMYLASE VARIANTS WITH ALTERED PROPERTIES - The present disclosure relates to variants of a parent glucoamylase having altered properties (e.g., improved thermostability and/or specific activity). In particular, the present disclosure provides compositions comprising the variant glucoamylases, including starch hydrolyzing compositions and cleaning compositions. The disclosure also relates to DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells. | 2012-06-14 |
20120149088 | ALKYLENE GLYCOLS AND POLYMERS AND COPOLYMERS THEREOF FOR DIRECT ISOLATION OF NUCLEIC ACID FROM EMBEDDED SAMPLES - Methods of directly isolating nucleic acid from an embedded biological sample are provided. An emulsified digest is generated in the presence of a thermostable protease, and an additive selected from an alkylene glycol, a poly(alkylene glycol), or a block copolymer having an average M | 2012-06-14 |
20120149089 | ANIMAL PRODUCT FREE SYSTEM AND PROCESS FOR PURIFYING A BOTULINUM TOXIN - Chromatographic processes and systems for purifying a | 2012-06-14 |
20120149090 | CELL FOR PREPARING COMPETENT CELL, METHOD FOR PREPARING COMPETENT CELL AND BACTERIAL STRAIN OF ESCHERICHIA COLI - The invention provides a cell for preparing competent cells, wherein the cell is capable of spontaneously accumulating self-producing trehalose therein and the cell is used for the preparation of competent cells. The invention also provides a method for preparing competent cells, including: culturing the cell for preparing the competent cell mentioned previously to obtain a cell suspension; placing the cell suspension into an ice bath; centrifuging the cell suspension to obtain a cell precipitate; mixing a transform reagent with the cell precipitate; and obtaining competent cells suspension. | 2012-06-14 |
20120149091 | SYSTEMS, DEVICES, AND METHODS FOR BIOMASS PRODUCTION - Systems, devices, and methods for cultivating biomasses. A bioreactor system is operable for growing photosynthetic organisms. The bioreactor system includes a bioreactor and a lighting system. The lighting system includes one more light-emitting substrates configured to light at least some of a plurality of photosynthetic organisms retained in the bioreactor. | 2012-06-14 |
20120149092 | Ethanol Production in Microorganisms - The present disclosure relates to methods and compositions for engineering photoautotrophic organisms to convert carbon dioxide and light into fatty acid esters and other molecules, including biofuels. The molecules are then secreted by the organism into a growth medium. | 2012-06-14 |
20120149093 | Method and Apparatus for Automating Chemical and Biological Assays - A device which collects specimen fluids or performs chemical or biological assays of the specimen fluid is provided with a specimen fluid receiver and a fluid actuated expandable trigger coupled to receive specimen fluid from the specimen fluid receiver such that a predetermined delay occurs before the trigger expands sufficiently to move another component of the device, and the specimen fluid interacts with a substance during the delay. The trigger is made of a material which expands substantially upon absorbing specimen fluid, and it is mounted and positioned so as to contact and move the other component of the device upon expanding through the absorption of specimen fluid. The other component may contain a surface coupled to receive specimen fluid from the specimen fluid receiver and the surface has an area which contains a substance which interacts with the specimen fluid. | 2012-06-14 |
20120149094 | Biological Sterilization Indicator and Method of Using Same - A biological sterilization indicator (BI) and a method of using same for assaying the lethality of a sterilization process. The BI can include a housing, which can include a first portion, and a second portion, which can be movable with respect to the first portion between a first and second position. The BI can further include a frangible container comprising a liquid. The BI can further include a spore reservoir and a projection positioned in the housing. The projection can be configured to fracture the container when the second portion of the housing is moved from the first position to the second position. The method can include maintaining a minimal cross-sectional area of space around the container when the second portion of the housing is in the first position, and fracturing the container in response to moving the second portion between the first and second positions. | 2012-06-14 |
20120149095 | DNA PROMOTERS AND ANTHRAX VACCINES - The invention is related to intracellularly induced bacterial DNA promoters and vaccines against | 2012-06-14 |
20120149096 | PRRS VIRUSES, INFECTIOUS CLONES, MUTANTS THEREOF, AND METHOD OF USE - The present invention provides isolated infectious polynucleotides, such as infectious clones, having a nucleotide sequence with identity to PRRS viruses such as VR-2332, Lelystad, or others, and optionally further including a deletion in a region of ORF1 that encodes the nsp2 polypeptide. | 2012-06-14 |
20120149097 | NONVIRAL VECTORS FOR DELIVERING POLYNUCLEOTIDES TO TARGET TISSUE - Methods and compositions for delivering polynucleotides are provided. One embodiment provides a non-viral vector comprising a recombinant polynucleotide-binding protein comprising a protein transduction domain operably linked to a targeting signal. | 2012-06-14 |
20120149098 | EXTRACTION OF PROCESS FOR MESENCHYMAL STROMAL STEM CELLS - Mesenchymal stromal stem cells are obtained starting with a biopsy sample from the iliac crest of the pelvis that is fragmented with surgical forceps in a saline solution and the saline solution containing the pulverised biopsy sample is then subjected to centrifugation, so to obtain mesenchymal stromal stem cells. The mesenchymal stromal stem cells are then selected by adhesion. | 2012-06-14 |
20120149099 | DIFFERENTIATION PROCESS OF MESENCHYMAL STEM CELLS AND THERAPEUTIC USE THEREOF - Process for inducing differentiation of mesenchymal stamina cells into neuroblasts and/or neurons that envisions the use of a differentiation solution consisting of retinoic acid and ethanol. | 2012-06-14 |
20120149100 | CARDIOMYOCYTE CELL POPULATIONS - The present invention provides methods for inducing the differentiation of cardiac progenitor cells and cell populations produced by the methods of the invention. The invention further provides a method of screening for agents that affect cardiomyocytes, and a method of cardiomyocyte replacement therapy. | 2012-06-14 |
20120149101 | METHODS AND KITS FOR REGULATING INTRACELLULAR TRAFFICKING OF A TARGET PROTEIN - A method and kits for regulating the intracellular trafficking of a target protein. In a retained state, the target protein is retained in a first compartment by an interaction with a hook protein. In a released state, the interaction is disrupted and the target protein traffics to a target compartment. | 2012-06-14 |
20120149102 | AGONIST AND ANTAGONIST PEPTIDES OF CARCINOEMBRYONIC ANTIGEN (CEA) - The invention provides a polypeptide comprising an agonist of a MHC Class I binding native sequence having amino acid substitution(s) and enhanced immunogenicity compared to the native sequence. The invention provides DNA encoding the polypeptide, as well as vectors and cells comprising the DNA and methods comprising the administration of the polypeptide. | 2012-06-14 |
20120149103 | Cells Useful for Immuno-Based Botulinum Toxin Serotype A Activity Assays - The present specification discloses clonal cell lines susceptible to BoNT/A intoxication, methods of producing such clonal cell lines, and methods of detecting Botulinum toxin serotype A activity using such clonal cell lines. | 2012-06-14 |
20120149104 | Cells Useful for Immuno-Based Botulinum Toxin Serotype A Activity Assays - The present specification discloses clonal cell lines susceptible to BoNT/A intoxication, methods of producing such clonal cell lines, and methods of detecting Botulinum toxin serotype A activity using such clonal cell lines. | 2012-06-14 |
20120149105 | Cells Useful for Immuno-Based Botulinum Toxin Serotype A Activity Assays - The present specification discloses clonal cell lines susceptible to BoNT/A intoxication, methods of producing such clonal cell lines, and methods of detecting Botulinum toxin serotype A activity using such clonal cell lines. | 2012-06-14 |
20120149106 | Cells Useful for Immuno-Based Botulinum Toxin Serotype A Activity Assays - The present specification discloses clonal cell lines susceptible to BoNT/A intoxication, methods of producing such clonal cell lines, and methods of detecting Botulinum toxin serotype A activity using such clonal cell lines. | 2012-06-14 |
20120149107 | PROCESS FOR THE CULTURING OF CELLS - The invention relates to a process for the culturing of cells, preferably E1-immortalized HER cells, more preferably PER.C6 cells in a reactor in suspension in a cell culture medium, wherein the cells produce a biological substance, preferably an antibody, wherein at least one cell culture medium component is fed to the cell culture and wherein the cell culture comprising the cells, the biological substance and cell culture medium is circulated over a separation system and wherein the separation system separates the biological substance from substances having a lower molecular weight than the biological substance and wherein the biological substance is retained in or fed back into the reactor. Preferably part of the substances of lower molecular weight is continuously removed from the cell culture. | 2012-06-14 |
20120149108 | CELL PRESERVATION METHOD - A method for cryopreservation of cells characterized by the use of a solution containing, as essential components, a sodium salt, a potassium salt, a saccharide, a cryoprotectant, and a hydrogencarbonate salt and/or a carbonate salt, the solution further optionally containing a component selected from the group consisting of proteins, magnesium salts, and calcium salts. According to the present invention, a method for cryopreservation of cells capable of maintaining a high viability rate after thawing, and a cryopreservation solution used in the cryopreservation are provided. In addition, by using the method for cryopreservation, the cells can be preserved in a state of maintaining a high viability rate even after thawing, and also maintaining their physiological functions; further, a cell washing step after freezing and thawing is unnecessary, thereby making it very useful in the fundamental researches of cells and the application studies on the medical treatment. | 2012-06-14 |
20120149109 | MODULATION OF TRANSTHYRETIN EXPRESSION - Compounds, compositions and methods are provided for modulating the expression of transthyretin. The compositions comprise oligonucleotides, targeted to nucleic acid encoding transthyretin. Methods of using these compounds for modulation of transthyretin expression and for diagnosis and treatment of diseases and conditions associated with expression of transthyretin are provided. | 2012-06-14 |
20120149110 | PROCESS FOR PRODUCTION OF BIOARTIFICIAL ORGAN - A method for inducing the differentiation of stem cells into tissue cells; a bioartificial organ, which contains the tissue cells; and a material for medical purposes, which contains the bioartificial organ are disclosed. Stem cells capable of proliferation, self-replication and differentiation are used and cultured by a hanging-drop method to three-dimensionally construct a cell mass of embryoid bodies, and the cell mass is cultured in the presence of HGF, GDNF, b-FGF, BMP7 and EGF. In this manner, the stem cells can be differentiated into tissue cells. A bioartificial organ can be produced using cells that have been differentiated into the tissue cells. Further, a material for medical purposes can be provided. | 2012-06-14 |
20120149111 | Porous Polymer Scaffolds for Neural Tissue Engineering and Methods of Producing the Same - The present invention relates to scaffolds that can physically guide cells, e.g. neurons, while best matching the material properties of native tissue. The present invention also relates to methods of generating such scaffolds, and for the use of such scaffolds, e.g. in spinal cord and peripheral nerve injury repair. The methods of the present invention include a uniquely controlled freeze casting process to generate highly porous, linearly oriented scaffolds. The scaffolds of the present invention not only comprise a highly aligned porosity, but also contain secondary guidance structures in the form of ridges running parallel to the pores to create a series of microstructured and highly aligned channels. This hierarchy of structural guidance aligns and guides neurite outgrowth down the channels created by the ridges, and keep neurites from branching perpendicular to the inter-ridge grooves. | 2012-06-14 |
20120149112 | METHOD FOR MAKING NERVE GRAFT - A method for making a nerve graft includes the following steps. A culture layer including a lyophobic substrate, a carbon nanotube film structure, and a protein layer is provided. The carbon nanotube film structure is sandwiched between the lyophobic substrate and the protein layer. A number of nerve cells are seeded on a surface of the protein layer away from the lyophobic substrate. The nerve cells are cultured until a number of neurites branch from the nerve cells and are connected between the nerve cells. | 2012-06-14 |
20120149113 | METHOD FOR MAKING NERVE GRAFT - A method for making a nerve graft includes the following steps. A culture layer including a carbon nanotube film structure and a protein layer is provided. The protein layer is located on a surface of the carbon nanotube film structure. A number of nerve cells are seeded on a surface of the protein layer away from the carbon nanotube film structure. The nerve cells are cultured until a number of neurites branch from the nerve cells and are connected between the nerve cells. | 2012-06-14 |
20120149114 | Methods For Cell Culture Using A Synthetic, Defined Collagen Mimetic Surface - The present invention discloses methods for enhancing cell attachment, cell proliferation and cell function using a surface which mimics a collagen coated surface. Advantageously, such methods employ a xeno-free, synthetic, chemically defined surface. | 2012-06-14 |
20120149115 | TARGETED GENOMIC REARRANGEMENTS USING SITE-SPECIFIC NUCLEASES - The present invention relates to a method for genomic DNA rearrangements, and more particularly, to a method for deletion, duplication, inversion, replacement, or rearrangement of genomic DNA using pairs of site-specific nucleases targeting two or more sites in the genome, a cell in which genomic DNA is deleted, duplicated, inverted, replaced, or rearranged by the same method, and a method for expressing the site-specific nucleases in cells. Further, the present invention relates to a method for inserting synthetic DNA molecules into the genome using site-specific nucleases targeting a pre-determined site in the genome, a cell in which DNA insertion occurs by the same method, and a method for expressing the site-specific nucleases in cells. | 2012-06-14 |
20120149116 | CELLULOSE DEGRADABLE YEAST AND METHOD FOR PRODUCTION THEREOF - The present invention provides a method for producing a cellulose degradable yeast, comprising the step of co-introducing genes coding for at least two cellulose-degrading enzymes into a yeast host via integration with a yeast δ sequence. According to the invention, a yeast having an improved cellulose degradation ability are provided. | 2012-06-14 |
20120149117 | HYDROGEN SULFIDE (H2S) DETECTION USING FUNCTIONALIZED NANOPARTICLES - Methods and related apparatuses and mixtures are described for spectroscopic detection of hydrogen sulfide in a fluid, for example a formation fluid downhole. A reagent mixture is combined with the fluid. The reagent mixture includes metal ions for reacting with hydrogen sulfide forming a metal sulfide, and a capping agent that limits growth of the insoluble metal sulfide species by electrosteric or steric stabilization. The particle growth is one of chemical reaction or significant aggregation, and the capping agent further functionalizes the reagent mixture to exhibit properties outside the natural characteristics of the metal sulfide species to allow for spectroscopic detection of the metal sulfide species. The combined mixture and fluid is then spectroscopically interrogated to detect the presence of the metal sulfide thereby indicating the presence of hydrogen sulfide in the fluid. The mixture also includes chelating ligands for sustaining thermal endurance of the mixture under downhole conditions. | 2012-06-14 |
20120149118 | APPARATUS AND METHOD USING ANTI-ADSORPTION AGENT TO FACILITATE SAMPLE MIXING AND ANALYSIS - An apparatus and method for analyzing a biological fluid sample is provided. The method includes the steps of: a) providing an analysis cartridge having a channel and an analysis chamber, wherein the channel is in fluid communication with the analysis chamber and includes at least one hydrophobic interior wall surface; b) admixing one or more anti-adsorption agents with fluid sample disposed within the channel, wherein the anti-adsorption agents are operable to inhibit adsorption of fluid sample onto the interior wall surface of the channel; c) moving the fluid sample into the analysis chamber; and d) analyzing the sample within the analysis chamber. | 2012-06-14 |
20120149119 | NUCLEIC ACID BASED FLUORESCENT SENSOR FOR MERCURY DETECTION - A nucleic acid enzyme comprises an oligonucleotide containing thymine bases. The nucleic acid enzyme is dependent on both Hg | 2012-06-14 |
20120149120 | CHIMERIC PROTEIN, METHOD FOR MANUFACTURING THE SAME, NANO-SENSOR IN WHICH THE CHIMERIC PROTEIN IS FIXED, AND APPLICATION THEREOF - There is provided a chimeric protein of capsid protein of Hepatitis B virus (HBV) and B domain of Staphylococcal protein A (SPA | 2012-06-14 |
20120149121 | OPTICAL CELL - A use composition monitor determines the concentration of peracid and/or peroxide in a use composition using a kinetic assay procedure. A sample mixture containing a sample of the use composition, a diluent and at least one reagent is prepared and analyzed using, for example, an optical detector. A reduced-turbulence optical detector can be used to improve collected response data. A reduced-turbulence optical detector can include a cell body disposed about a length of transparent tubing. The cell body positions one or more emitter/receiver pairs about the transparent tubing. Thus, tube junctions are eliminated and sample flow within the tube is substantially turbulence free. | 2012-06-14 |
20120149122 | DEVICE AND METHOD FOR DETERMINING THE CONCENTRATION OF A COMPOUND IN AN AQUEOUS OR GASEOUS PHASE - A device for determining the concentration of a compound in an aqueous phase in a dynamic manner and while flowing, and a device ( | 2012-06-14 |
20120149123 | Low Temperature Method to Enhance Detection of Magnetic Beads - Detection of magnetic beads at temperature below room temperature can increase the signal level significantly as compared to the same detection when performed at room temperature. Additional improvement is obtained if the beads are below 30 nm in size and if deviations of bead size from the median are small. A preferred format for the beads is a suspension of super-paramagnetic particles in a non-magnetic medium. | 2012-06-14 |
20120149124 | DEVICE FOR COLLECTION AND ASSAY OF ORAL FLUIDS - A method and a device for collection and assay of oral fluids are disclosed. The method places an assay device into an oral cavity, removes the device, and determines the presence or absence of an analyte. The assay device comprises an assay portion housing a lateral flow assay strip, a neck portion extending from the assay portion and forming a channel for fluid delivery to the assay strip; a collection strip in fluid communication with the lateral flow assay strip; and a blocking strip coupled between and in flow communication with the lateral flow assay strip and the collection strip. The channel is defined by a narrow part proximal to the assay portion and a part which receives oral fluid and has a substantially wider channel width. The collection strip has a first portion disposed within the channel and a second portion protruding outwardly from the neck opening. | 2012-06-14 |
20120149125 | Ion Population Control for an Electrical Discharge Ionization Source - A method of providing reagent ions to a mass spectrometer comprises delivering a reagent species to a reagent ionization volume via a passageway at a flow rate. Using previously acquired information, an injection time duration is calculated for injecting reagent ions that are formed in the reagent ionization volume into a reaction region of the mass spectrometer. A determination is made as to whether the calculated injection time duration is within a specified range of injection time duration values. When it is determined that the calculated injection time duration falls outside of the specified range of injection time duration values, the flow rate at which the reagent species is delivered to the ionization volume is adjusted. | 2012-06-14 |
20120149126 | Fluidics Apparatus and Fluidics Substrate - A fluidics apparatus is disclosed for manipulation of at least one fluid sample, typically in the form of a droplet. The apparatus has a substrate surface with a sample manipulation zone for location of the fluid sample. A transducer arrangement such as an interdigitated electrode structure on a piezoelectric body provides surface acoustic waves at the substrate surface for manipulation of the fluid sample. The substrate surface has an arrangement of surface acoustic wave scattering elements forming a phononic crystal structure for affecting the transmission, distribution and/or behaviour of surface acoustic waves at the substrate surface. Also disclosed is a method for lysing a cell. In this method, the cell is comprised in a fluid sample contacting a substrate surface, the method comprising providing surface acoustic waves at the substrate surface, such that the cell lyses. | 2012-06-14 |
20120149127 | SAMPLE ANALYZER AND SAMPLE ANALYZING METHOD - The present invention is to present a sample analyzer for analyzing a target substance in a sample by carrying out a target substance separating process for separating a complex containing the target substance and a magnetic particle from other substances other than the complex. The sample analyzer executes the target substance separating process with respect to a second container held by a second holder with a second nozzle while executing the target substance separating process with respect to a first container held by a first holder with a first nozzle, and completes the target substance separating process with respect to the first container with the first nozzle and completes the target substance separating process with respect to the second container with the second nozzle. | 2012-06-14 |
20120149128 | ASSAYS AND ASSAY DEVICES - Methods and apparatus for conducting analyte assays, including multiplexed assays are described. Such methods include assays adapted for low volume assay devices in which assays can be performed using undiluted biological liquid samples by exchanging binding medium with detection medium, using layered labels, and/or using droplet based mixing in an assay device. | 2012-06-14 |
20120149129 | LOW COST, PORTABLE SENSOR FOR MOLECULAR ASSAYS - An integrated sensor that is capable of discriminating the distance of a label from the sensor without using an optical signal. The label is attached to a single probe molecule or a group of probe molecules that interacts with a single or group of target molecules. As a consequence of this interaction, the probe molecule and/or the target molecule undergo a conformal change. This conformal change leads to perturbations in the distance of the label from the sensor. Thus, measurements and properties such as the concentration and the identity of one or more target molecules can be discerned from signals generated by the sensor (or by a plurality of sensors in a sensor array) and subjected to analysis using general purpose programmable computers programmed with suitable software that controls the analytical process, and such measurements and properties can be provided as a result of the analysis. | 2012-06-14 |
20120149130 | POLYPEPTIDES FOR THE IN VITRO ASSESSMENT OF THE SENSITISING POTENTIAL OF A TEST COMPOUND - The invention relates to novel polypeptides and to the use thereof for the in vitro assessment of the sensitising potential of a test compound, to a method for the in vitro assessment of the sensitising potential of a test compound, to an in vitro method for selecting a compound suitable for reducing the sensitisation, as well as to kits for implementing such methods. | 2012-06-14 |
20120149131 | PROCALCITONIN FOR THE PROGNOSIS OF ADVERSE EVENTS - The present invention relates to an in vitro method for the prognosis of an adverse event in asymptomatic subjects comprising the determination of the level of Procalcitonin (PCT) or a fragment thereof or a precursor or fragment thereof having at least 12 amino acid residues in a sample of a bodily fluid from said subject and the correlation of the determined level to a potential risk of sustaining an adverse event. | 2012-06-14 |
20120149132 | ANALYZER AND ANALYZING METHOD - The present invention is to present an analyzing method for analyzing a target substance contained in a sample using a reagent containing magnetic particles. The method comprises steps of: (a) magnetically capturing magnetic particles in a container with a first magnetic force generating member arranged on a lower side of the container accommodating a liquid specimen containing the magnetic particles; (b) transferring the container to a target substance separating section after the step (a); and (c) in the target substance separating section, discharging a cleaning liquid into the container and aspirating a liquid in the container while magnetically capturing the magnetic particles in the container with a second magnetic force generating member. | 2012-06-14 |
20120149133 | MEMS PROCESS METHOD FOR HIGH ASPECT RATIO STRUCTURES - Methods for the controlled manufacture of high aspect ratio features. The method may include forming a layer stack on a top surface of a substrate and forming features in the layers of the layer stack. The high aspect ratio features may be defined using a resist layer that is patterned with a photolithographic condition. After removing at least one of the layers removed from the top of the layer stack, a feature dimension may be measured for features at different locations on the substrate. The method may further include changing the photolithographic condition based on the measured dimension and processing another substrate using the changed photolithographic condition. | 2012-06-14 |
20120149134 | METHODS AND APPARATUS FOR THINNING, TESTING AND SINGULATING A SEMICONDUCTOR WAFER - A wafer translator is provided with a patterned layer of wafer bonding thermoset plastic and is removably attached with a wafer so as to form a wafer/wafer translator pair. The wafer translator acts as a mechanical support during a thinning process as well as during a wafer dicing operation. The singulated integrated circuits are then removed from the wafer translator. In some embodiments, wafer level testing of the integrated circuits on the wafer is performed subsequent to the wafer thinning process but before the wafer and wafer translator are separated. In other embodiments, wafer level testing of the integrated circuits on the wafer is performed subsequent to the wafer dicing operation but before the diced wafer and wafer translator are separated. | 2012-06-14 |
20120149135 | SEMICONDUCTOR DEVICE MANUFACTURING METHOD THAT ALLOWS REWORK RATE IN MANUFACTURING STEP TO DECREASE - A semiconductor device manufacturing method includes: forming a first pattern in a first film to be processed on a semiconductor substrate; measuring a first distance, which is a dimension in a predetermined direction in the first pattern; forming a second film to be processed on the first pattern; forming a second pattern in a photoresist formed on the second film to be processed; and measuring a second distance, which is a dimension in a predetermined direction in the second pattern. Whether or not the second pattern is defective is determined based on either the first distance or a value calculated from the first and second distances. | 2012-06-14 |
20120149136 | FABRICATION METHOD OF SEMICONDUCTOR INTEGRATED CIRCUIT DEVICE - In the fabrication of a semiconductor integrated circuit device, a 2D-3D inspection technique for solder printed on a substrate is provided which permits easy preparation of data and easy visual confirmation of a defective portion. In a substrate inspecting step, first, a 3D inspection is performed, followed by execution of 2D inspection, whereby a 2D picked-up image of the portion of a pad determined to be defective can be displayed on a larger scale simultaneously with the end of inspection, thereby providing an environment for efficient visual confirmation of the defect. Further, by subjecting a raw substrate to measurement at the time of preparing inspection data, a relation between an original height measurement reference generated automatically by the inspection system and the height of a pad upper surface is checked, whereby it is possible to measure the height and volume of printed solder based on the pad upper surface. | 2012-06-14 |
20120149137 | Methods of Combinatorial Processing For Screening Multiple Samples on a Semiconductor Substrate - In embodiments of the current invention, methods of combinatorial processing and a test chip for use in these methods are described. These methods and test chips enable the efficient development of materials, processes, and process sequence integration schemes for semiconductor manufacturing processes. In general, the methods simplify the processing sequence of forming devices or partially formed devices on a test chip such that the devices can be tested immediately after formation. The immediate testing allows for the high throughput testing of varied materials, processes, or process sequences on the test chip. The test chip has multiple site isolated regions where each of the regions is varied from one another and the test chip is designed to enable high throughput testing of the different regions. | 2012-06-14 |
20120149138 | Method for Manufacturing Heat Dissipation Bulk of Semiconductor Device - A method for manufacturing a heat dissipation bulk of a semiconductor device including the following steps is described. An electrically conductive layer is formed to cover a surface of a temporary substrate. At least one semiconductor chip is connected to the electrically conductive layer by at least one metal bump, wherein the at least one metal bump is located between the at least one semiconductor chip and the electrically conductive layer. A metal substrate is formed on the electrically conductive layer, wherein the metal substrate fills up a gap between the at least one semiconductor chip and the electrically conductive layer. The temporary substrate is removed. | 2012-06-14 |
20120149139 | LOW-COST LARGE-SCREEN WIDE-ANGLE FAST-RESPONSE LIQUID CRYSTAL DISPLAY APPARATUS - A method of fabricating an IPS active matrix substrate, and said substrate constituting an active matrix display device, characterized in that: a photolithographic procedure is performed for three times for the manufacture: forming a gate electrode, a comb pixel electrode, a common electrode for shielding a video signal line (or a source electrode), a contact pad in said pixel electrode, and a video signal line for shielding said contact pad in common electrode, forming a separate thin film semiconductor layer component, and a contact hole, forming a source electrode, a drain electrode, a common electrode at the center of a pixel and a comb common electrode, such that after an ohmic contact layer of a channel portion of said thin film transistor is dry etched, a partial film of a passivation layer is formed by a silicon nitride film by using a mask deposition method is provided. | 2012-06-14 |
20120149140 | LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND VAPOR DEPOSITION APPARATUS - To provide a light-emitting element and a light-emitting device which can be designed and manufactured with redundancy. A light-emitting element of the invention includes a pair of electrode, and a layer containing a light-emissive substance between the pair of electrodes. The layer containing a light-emissive substance includes a layer containing a composite material, and the layer containing a composite material includes an organic compound and an inorganic compound. The concentration ratio of the organic compound to the inorganic compound changes periodically. The layer containing a composite maternal can be changed in electrical characteristics without changing the composition ratio of the organic compound to the inorganic compound in the layer or changing the kind of compounds used for the layer. | 2012-06-14 |
20120149141 | AlGaInN-Based Lasers Produced Using Etched Facet Technology - A process for fabricating AlGaInN-based photonic devices, such as lasers, capable of emitting blue light employs dry etching to form device waveguides and mirrors. The dry etching is preferably performed using a Chemically Assisted Ion Beam Etching (CAIBE) system. | 2012-06-14 |
20120149142 | Betavoltaic battery with a shallow junction and a method for making same - This is a novel SiC betavoltaic device (as an example) which comprises one or more “ultra shallow” P+ N | 2012-06-14 |
20120149143 | Method for Manufacturing a Solar Cell - In the existent method for manufacturing a solar cell, manufacture of a solar cell having a quantum well having a crystalline well layer and capable of controlling the thickness of the well layer was difficult. A quantum well having an amorphous well layer, comprising a barrier layer and an amorphous well layer is formed and then the quantum well having the amorphous well layer is annealed thereby crystallizing the amorphous well layer to form a quantum well having a crystalline well layer. By applying energy density applied to the amorphous well layer at an energy density of 1.26 J/mm | 2012-06-14 |
20120149144 | METHOD FOR MANUFACTURING SOLAR CELL - A method for manufacturing a solar cell is presented. The method includes: forming an amorphous silicon layer on a first surface of a light absorbing layer; doping the amorphous silicon layer with a dopant; forming a dopant layer by diffusing the dopant into the amorphous silicon layer with a laser; forming a semiconductor layer by removing the dopant that remains outside the dopant layer; etching the surface of the semiconductor layer by using an etchant; forming a first electrode on the semiconductor layer; and forming a second electrode on a second surface of the light absorbing layer. | 2012-06-14 |
20120149145 | METHOD FOR MANUFACTURING IMAGE SENSOR - A method for manufacturing an image sensor, wherein the method comprises several steps as follows: A semiconductor base doped with dopants having a first-type electrical conductivity is provided, wherein the semiconductor base comprises a handle wafer, an oxide insulator disposed on the handle wafer, and a silicon layer disposed on the oxide insulator. A front end process is then conducted, to form at least one imaging pixel disposed in the silicon layer and at least one metal layer disposed on the imaging pixel, whereby the first-type electrical dopants can be driven into the silicon layer to form a doping layer with the first-type electrical conductivity over the oxide insulator. | 2012-06-14 |
20120149146 | CONFINED RESISTANCE VARIABLE MEMORY CELL STRUCTURES AND METHODS - Confined resistance variable memory cell structures and methods are described herein. One or more methods of forming a confined resistance variable memory cell structure includes forming a via in a memory cell structure and forming a resistance variable material in the via by performing a process that includes providing a germanium amidinate precursor and a first reactant to a process chamber having the memory cell structure therein and providing an antimony ethoxide precursor and a second reactant to the process chamber subsequent to removing excess germanium. | 2012-06-14 |