23rd week of 2010 patent applcation highlights part 59 |
Patent application number | Title | Published |
20100144868 | Novel Neuroprotective Compounds and Uses Thereof - Disclosed are novel hybrid compounds having a fullerene core residue, one or more bioavailability enhancing moieties and one or more glutamate receptor ligand residues, whereby the bioavailability enhancing moiety allow the compound to reach an effective concentration in physiological media and pass the blood-brain barrier, as defined in the specification. Also disclosed are pharmaceutical compositions containing these hybrid compounds and uses thereof as antioxidants and/or neuroprotective agents for the treatment of medical conditions associated with oxidative stress and/or neural damage, such as, for example, neurological diseases, disorders and trauma, and hence in the treatment of CNS-associated diseases, disorders and trauma, as well as to uses thereof as antiviral, antibacterial, antiglycemic, antiarrhythmic, antidepressant and antitumor agents. | 2010-06-10 |
20100144869 | Conjugates Comprising a gaba-or glycine compound, pharmaceutical compositions and combinations thereof as well as their use in treating cns disorders - A novel use of conjugates of psychotropic drugs (e.g., antidepressants or anti-epileptic drugs) and organic acids such as GABA in the treatment of pain is disclosed. A novel GABA conjugate and uses thereof is also disclosed. | 2010-06-10 |
20100144884 | NOVEL 3-PHENYL ACRYLIC ACID COMPOUND ACTIVATORS OF TYPE PPAR RECEPTORS AND PHARMACEUTICAL/COSMETIC COMPOSITIONS COMPRISED THEREOF - Novel 3-phenyl acrylic acid compounds have the following general formula (I): | 2010-06-10 |
20100144885 | HISTONE ACETYL TRANSFERASE ACTIVATORS AND HISTONE DEACETYLASE INHIBITORS IN THE TREATMENT OF ALCOHOLISM - The present invention relates to the reduction of a symptom of an alcohol withdrawal state comprising administering a modulator of histone acetylation. | 2010-06-10 |
20100144886 | METHOD FOR TREATING PULMONARY ARTERIAL HYPERTENSION - The present invention is directed to methods comprising administering a composition comprising a therapeutically effective amount of (R)-verapamil, a derivative thereof, or a pharmaceutically acceptable salt thereof, wherein the composition treats, prevents and/or manages at least one condition having MT1 receptor, 5-HT2B receptor and L-type calcium channel activity and releases the (R)-verapamil, a derivative thereof or a pharmaceutically acceptable salt thereof to exhibit a co-primary activity on the MT1 receptor, the 5-HT | 2010-06-10 |
20100144888 | PESTICIDAL METHODS AND COMPOSITIONS FOR MODULATING GABA RECEPTORS - Methods for using pesticidal compositions containing a pesticidally acceptable carrier, at least one GABA receptor modulator compound as a pesticidally active ingredient and optionally an additional compounds, such as a synergist, and methods for using same. | 2010-06-10 |
20100144890 | USE OF A SURFACTANT FOR THE PREPARATION OF A FORMULATION FOR THE TREATMENT OF ADIPOSE DISEASES - Use of a mixture comprising at least one non-aromatic surfactant having a plurality of ether and/or ester groups and at least one carrier agent for the preparation of a formulation for the treatment of adipose tissue disease and/or condition with improved bioavailability and lipolysis behaviour. | 2010-06-10 |
20100144902 | BIOCOMPATIBLE RAPID-GELATING HYDROGEL AND ASSOCIATED PREPARATION METHOD OF SPRAY - This invention discloses a preparation method for biocompatible rapid-gelating hydrogel. Wherein, hydrogel is formed by rapid chemical-crosslinking using the mixing and chemical-crosslinking reaction under specified conditions between several active compound components. The preparation method comprises the following steps: (1) The solution containing biocompatible thiolated macromolecular derivatives (component A) and biocompatible thiol reactive crosslinking agents (component B) mutually mix to form reactive mixture with specified crosslinking conditions; (2) the reactive mixture forms the hydrogel. The invention also discloses a preparation method for novel rapid-gelating hydrogel spray and an application in medical field. This invention has the advantages of good biocompatibility, no by-products, good stability, convenient use, small amount of raw materials used, suitable for many medical application, etc. | 2010-06-10 |
20100144905 | BLENDING PLASTIC AND CELLULOSE WASTE PRODUCTS FOR ALTERNATIVE USES - The present invention relates to methods for reclaiming plastics and cellulose materials for use in a variety of applications, including as alternative fuel sources. According to one embodiment of the invention, waste is received which includes cellulose materials and plastics. Such materials are sorted from other materials and the cellulose and plastic materials are shredded or ground and then blended together. The blended materials can then be fed to an energy converter, such as a combustion unit or a gasifier, where they are burned as fuel source or used to create synthetic gas. In other embodiments, the blended materials are heated or have a binding element added thereto. Such mixture is then compressed to form a desired shape or sized object, and that object can then be packaged, distributed or used. The blended object can be used as a fuel source, or as a building, sound attenuation, or insulation material. | 2010-06-10 |
20100144908 | PROCESS FOR THE REGENERATION OF AN ION EXCHANGE RESIN USING SULFUROUS ACID - A diamine absorbent that contains heat stable salts is regenerated using an ion exchange process wherein the cation exchange resin is regenerated using sulfurous acid reflux. | 2010-06-10 |
20100144910 | PROCESS TO PRODUCE POLYMERS - Catalyst systems for producing olefin polymers, methods of making such catalyst systems, and processes for producing olefin polymers using such catalyst systems are provided. The catalyst system comprises a first component and a second component, where the first component comprises chromium on a support, where the support comprises phosphated alumina, and the second component comprises: (1) a metal halide compound, a transition metal compound, and a precipitating agent, or (2) a substituted or unsubstituted dicyclopentadienyl chromium compound deposited onto a calcined oxide carrier, where the carrier includes silica, alumina, aluminophosphate, or any mixed oxide thereof. | 2010-06-10 |
20100144921 | ANTIMICROBIAL ACID-CATALYZED COATING COMPOSITIONS - The antimicrobial acid-catalyzed coating composition of the invention is an acid-catalyzed coating composition formulated with at least one antimicrobial agent to provide antimicrobial activity to the coating composition and an article coated therewith. | 2010-06-10 |
20100144924 | POLYMERIZABLE COMPOSITION - A polymerizable composition is obtained by mixing a metathesis polymerization catalyst including benzylidene(1,3-dimethyl-4-imidazolidin-2-ylidene)(tricyclohexylphosphine)ruthenium dichloride, a cycloolefin monomer such as 2-norbornene or tetracyclo[6.2.1.1 | 2010-06-10 |
20100144925 | Plasters and Renders and Paints, Copolymer Dispersions and Their Use - Compositions containing selected polymer dispersions, colloidal silica, fillers and pigments are described. | 2010-06-10 |
20100144929 | Liquid solventless synthetic-rubber-based composition - A synthetic-rubber-based composition that consists of a low-molecular-weight rubber selected from polybutadiene comprising about 75% to about 92% cis-1,4 units, sulfur, a vulcanization accelerator, and an active filler wherein the sulfur, accelerator, and active filler are each present in the form of powder having a particular particle-size range. Additionally, this composition may be used to form coatings and rubber concretes. | 2010-06-10 |
20100144930 | OXIDATION RESISTANT HIGHLY-CROSSLINKED UHMWPE - The present invention relates to highly cross-linked UHMWPE, which is possessed of an improved oxidation resistance, as well as a method for making the same. The UHMWPE material of the current invention is combined with an anti-oxidant compound or a free-radical scavenger prior to formation. Once the UHMWPE with the added material has been formed and treated with gamma or electron beam irradiation, it shows an improved wear resistance and also a good resistance to oxidation. Such a material, is particularly interesting for the field of making replacement joint implants. | 2010-06-10 |
20100144951 | RUBBER COMPOSITION - A natural rubber wet masterbatch rubber composition comprising a mixture of a natural rubber latex with a slurry solution containing a carbon black dispersed therein, which satisfies the followings: (1) a CATB specific surface area (m | 2010-06-10 |
20100144955 | Thermoplastic polymer mixtures, and applications thereof - Thermoplastic polymer mixture (M) comprising at least one poly(aryl ether ketone) (P1), at least one poly(arylene sulfide) (P2), and between 0 and 25 wt. % of the total weight of the thermoplastic mixture (M), of a thermoplastic polymer material (P3) consisting of (i) at least one poly(biphenyl ether sulfone) (P3a), and/or (ii) at least one poly(ether imide) (P3b), and/or at least one poly(ether imide sulfone) (P3c), wherein: the combined weight amount of the poly(aryl ether ketone) (P1) and the poly(arylene sulfide) (P2), based on the total weight of the polymer mixture (M), is of at least 30%, and the weight amount of the poly(aryl ether ketone) (P1), based on the combined weight of the poly(aryl ether ketone) (P1) and the poly(arylene sulfide) (P2), is of at most 90%. | 2010-06-10 |
20100144956 | RESIN COMPOSITION FOR AQUEOUS COATING MATERIAL, METHOD FOR PRODUCING THE SAME, AND AQUEOUS COATING MATERIAL - A resin composition for an aqueous coating material that includes a propylene-butene resin component and/or propylene-ethylene-butene resin component (A), and a (meth)acrylic resin component (B), wherein the mass ratio between the propylene-butene resin component and/or propylene-ethylene-butene resin component (A) and the (meth)acrylic resin component (B) is within a range from 15:85 to 75:25. Also disclosed are a method for producing such a resin composition and an aqueous coating material. The present invention is able to provide a resin composition for an aqueous coating material that is useful as a binder within an aqueous coating material that uses no organic solvents or chlorine compounds, and yet exhibits excellent adhesion to polyolefin-based resins and is capable of forming a coating film that is resistant to discoloration and exhibits favorable resistance to the oils contained within gasoline, cosmetic products and foodstuffs and the like, and is also able to provide a method for producing the resin composition and an aqueous coating material that uses the resin composition. | 2010-06-10 |
20100144957 | CURABLE MATERIAL CONTAINING PHOTOPOLYMERIZABLE POLYMER AND CURED OBJECT - There is provided a curable material capable of manufacturing a cured object by ultraviolet irradiation without using a photopolymerization initiator or additive and a cured object obtained therefrom, and, in particular, provided a film-forming material capable of manufacturing a cured film and the cured film obtained therefrom. The curable material comprises a branched and/or linear photopolymerizable polymer having an N,N-dialkyldithiocarbamate group as a functional group at a molecular end. The film-forming material is composed of the curable material, and the cured object is obtained by photopolymerization of the curable material to effect inter-bonding and the cured film is obtained by photopolymerization of the film-forming material to effect inter-bonding and form a film. | 2010-06-10 |
20100144959 | PREPARATION OF ALKOXY- AND/OR HALOSILANE (POLY)SULFIDES AND COUPLING AGENTS COMPRISED THEREOF - At least one (poly)thio alkoxy and/or halosilane is/are prepared by reaction of at least one sulfur-containing reagent with at least one alkoxy and/or halosilane, wherein an ionic addition of a sulfur-containing reagent to an alkoxy and/or halosilane is preferably conducted with thermal and/or actinic activation; the novel polythio alkoxy and/or halosilanes of formula (III.2) thus prepared are particularly useful as coupling agents in elastomeric compositions containing a white filler of the silica type and having the formula (III.2) wherein, for example, R | 2010-06-10 |
20100144971 | Impact Modified Polylactide Resins - Polylactide resins are blended with core-shell rubber particles to improve impact strength. A good balance of impact strength and transparency is achieved when the rubber particles are distributed within the polymer matrix such that most of them exist as single particles or agglomerates having a diameter of 150 nanometers or more, and the number average size of the particles and agglomerates is not more than 210 nanometers. | 2010-06-10 |
20100144972 | POLYMER COMPOSITION, TRANSFERRING BELT FOR ELECTROPHOTOGRAPHY, IMAGE-FORMING APPARATUS AND METHOD FOR PRODUCING POLYMER COMPOSITION - A polymer composition containing two kinds of polymers and having a difference in its glass transition temperature of 3° C. or lower between before and after heat-treatment by getting it through a space between two parallel faces in a molten state. | 2010-06-10 |
20100144975 | Polypropylene Resin Composition With Good Transparence And Good Impact Strength - Provided is a polypropylene resin composition having excellent impact resistance, impact strength at low temperature and transparence comprising ethylene-alpha olefin copolymer (c) to a polypropylene resin composition in which the ratio of viscosity is regulated by adjusting molecular weight of propylene-alpha olefin random copolymer (a) and propylene-alpha olefin elastic copolymer (b), thereby regulating impact resistance and flexural modulus of the polypropylene resin composition and improving transparence; therefore, applying as various products including cold-storage containers for freezer and refrigerator, food packaging container, extrusion blow molding material, film, sheet and bottle cap, etc. | 2010-06-10 |
20100144978 | METHOD OF MAKING POLYGLYCEROL ESTERS - Polyglycerol carboxylic acid esters are made by reaction of a, typically C | 2010-06-10 |
20100144980 | RESIN POWDER COMPOSITION FOR SLUSH MOLDING AND MOLDED ARTICLES - The present invention provides a resin powder composition for slush molding which can give slush molded articles with more excellent hydrolysis resistance. The present invention relates to a resin powder composition for slush molding which is characterized by comprising as the main component a thermoplastic polyurethane resin powder, preferably a thermoplastic polyurethane elastomer powder, and containing a polycarbodiimide prepared by polymerizing tetramethylxylylene diisocyanate, alkoxy terminated one having a number average molecular weight of 500 to 30,000. | 2010-06-10 |
20100144992 | FUNCTIONALIZED POLYFLUORENES FOR USE IN OPTOELECTRONIC DEVICES - The present invention relates to process comprising reacting a polyfluorenes comprising at least one structural group of formula I | 2010-06-10 |
20100144994 | Process for Separation of Tetrafluoroethylene from Carbon Dioxide using Ionic Liquids - A process for separating tetrafluoroethylene from a mixture comprising tetrafluoroethylene and carbon dioxide by contacting the mixture with at least one ionic liquid. | 2010-06-10 |
20100144996 | INJECTIBLE CYANOACRYLATE-FUNCTIONALIZED POLYISOBUTYLENES - The present invention generally relates to injectible polyisobutylene polymer compounds. More specifically, the N present invention relates to injectible polyisobutylene polymer compounds that are designed for various biological and medical applications. In one embodiment, the present invention relates to injectible functionalized polyisobutylene polymer compounds that are designed for various biological and medical applications. In another embodiment, the present invention relates to injectible cyanoacrylate-functionalized polyisobutylene polymer compounds. | 2010-06-10 |
20100144998 | PROCESS FOR FINE PURIFICATION OF 1-BUTENIC STREAMS - The invention relates to a process for preparing 1-butenic fractions having less than 2000 ppm of isobutene in relation to 1-butene from technical mixtures of C | 2010-06-10 |
20100144999 | METHOD FOR PRODUCING AROMATIC POLYMER - Disclosed is a method for producing an aromatic polymer characterized in that an aromatic compound represented by the formula (I) below is polycondensed in the presence of a palladium complex containing a phosphine compound represented by the formula (II) below. (I) (In the formula (I), Ar represents a bifunctional organic group containing an aromatic ring; X represents a halogen atom, a nitro group or a group expressed as —SO | 2010-06-10 |
20100145031 | METHODS FOR PRODUCING ANTIBODIES FROM PLASMA CELLS - The invention relates to methods of producing antibodies, including monoclonal antibodies, comprising culturing a limited number of plasma cells. It also relates to methods of identifying antibodies by performing assays on the antibodies produced by the cultured plasma cells to determine their function, binding specificity, epitope specificity, and/or their ability to neutralize a toxin or a pathogen. The invention also relates to antibodies and antibody fragments produced by the methods of the invention as well as methods of using the antibodies and antibody fragments. | 2010-06-10 |
20100145033 | NOVEL ORTHOGONAL PROCESS FOR PURIFICATION OF RECOMBINANT HUMAN PARATHYROID HORMONE (RHPTH) (1-34) - The present invention discloses a process for the preparation of rhPTH (1-34) also known as teriparatide by con-struction of a novel nucleotide, as an NcoI.IXhoI fragemt as set forth in SEQ. ID. No.:1 encoding a chimeric fusion protein as set forth in SEQ.ID. No.:2 comprising of a fusion partner consisting of 41 amino acids belonging to | 2010-06-10 |
20100145035 | METHOD OF SYNTHESIZING MACROLIDE COMPOUNDS - The present invention relates to methods for synthesizing macrolide compounds which are known to have antibacterial activity, and are useful in the therapy of bacterial infections in mammals. More specifically, the invention relates to methods for synthesizing the macrolide antibiotic, gamithromycin utilizing a novel configuration of catalysts, chemical structures, and/or methods. An embodiment of the present invention may include allowing multiple chemical reactions to proceed without the isolation of chemical intermediates. Thus, multiple reactions may occur in one reaction vessel allowing for a considerable decrease in the cycle-time. The present invention also provides a novel method for inhibiting degradation while isolating a structure of a pharmaceutical composition. | 2010-06-10 |
20100145039 | siRNA targeting nucleoporin 62kDa (Nup62) - Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for Nup62 | 2010-06-10 |
20100145040 | Benzazepine Derivatives For The Treatment of Neurological Disorders - The present invention relates to novel benzazepine derivatives having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders. | 2010-06-10 |
20100145043 | 2,4-Disubstituted-5-Aminocarbonyl-1,3-Thiazole Derivatives For Therapeutic Agent Of Antiinflammatory Disease, Method Thereof For Preparation, Therapeutic Agent For Antiinflammatory Disease Induced By SPC Activity Containing The Same - Disclosed herein are 2,4-disubstituted-5-aminocarbonyl-1,3-thiazole derivatives, a preparation method thereof, and a therapeutic agent for treating inflammatory diseases induced by SPC, which contains the derivative as an active ingredient. The anti-inflammatory effect of the 2,4-disubstituted-5-aminocarbonyl-1,3-thiazole derivatives was analyzed through a test employing human dermal cells and an animal test using mice and, as a result, it was found that the derivatives showed excellent inhibitory activity on SPC receptor compared to thiazole derivatives known in the prior art. Thus, the 2,4-disubstituted-5-aminocarbonyl-1,3-thiazole derivatives or pharmaceutically acceptable salts thereof are useful as active ingredients in therapeutic agents for treating inflammatory diseases, such as inflammation, pruritus and skin infection, which appear in atopic dermatitis and other diseases induced by SPC activity. | 2010-06-10 |
20100145044 | Organometallic Complex and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Same - An organometallic complex having a structure represented by the general formula (G1) is synthesized and applied to a light-emitting element. | 2010-06-10 |
20100145045 | USE OF FUNGICIDES FOR THE TREATMENT OF FISH MYCOSES - Process for the protection of fish and invertebrates and all their stages of development against mycoses caused by fungi of the genera | 2010-06-10 |
20100145046 | Substituted 3-hydroxy-delta-lactones from epoxides - Catalysts and methods for the carbonylation of epoxides to substituted 3-hydroxy-δ-lactones and β-lactones are disclosed. | 2010-06-10 |
20100145047 | INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE - Provided herein are compounds of the formula (I): | 2010-06-10 |
20100145064 | METHOD FOR THE PREPARATION OF ZOLMITRIPTAN - A method for the preparation of zolmitriptan or its pharmaceutically acceptable salts, comprising isolation of a crystalline salt of zolmitriptan, its optional re-purification and conversion to the substance of formula (III). Zolmitriptan hydrochloride in the crystalline state. | 2010-06-10 |
20100145065 | PROCESS FOR PREPARING BENZIMIDAZOLE COMPOUNDS - Provided are methods for the synthesis of heterocyclic compounds such as benzimidazole carboxylic acid core structures having Formula Ia-1 and their synthetic intermediates: wherein Z, X | 2010-06-10 |
20100145066 | PHOSPHONATE COMPOUNDS - Novel phosphonate compounds are disclosed embodying an aminophosphonate moiety and a selected reaction partner. These compounds offer beneficial alternatives, and additional possibilities, to extant phosphonates and are capable of delivering desirable benefits from an application standpoint and from a compatibility standpoint broadly. | 2010-06-10 |
20100145067 | NOVEL CARBAZOLES DERIVATIVE AND USE THEREOF - The invention discloses a novel carbazole derivative which has at least two carbazole structures in the molecule, can form a stable amorphous film by itself at normal temperature or higher, has a high glass transition temperature, and can be suitably used as an organo-electronic functional material. The following compound having the formula | 2010-06-10 |
20100145068 | Dendritic Photoactive Compound Comprising Oxime Ester And Method For Preparing The Same - The present invention relates to a dendritic photoactive compound that comprises oxime ester and a method for producing the same. Since the compound according to the present invention comprises two or more oxime ester groups and chromophores in one molecule at the same time, the solubility in respects to the organic solvent and the efficiency for producing a radical by absorbing ultraviolet rays are excellent. In addition, it can act as an effective initiator in respects to the photopolymerization of the unsaturated group, in particular, the acryl compound | 2010-06-10 |
20100145070 | ANTI-CANCER COMPOUND AND MANUFACTURING METHOD THEREOF - Anti-cancer compounds and manufacturing methods thereof are disclosed. The anti-cancer compounds are 1,8-diamidoanthraquinone derivatives with amino compounds. The manufacturing method includes the steps of: add 1,8-bis(chloroacetamido)anthraquinone or 1,8-bis(3-chloropropionamido)-anthraquinone with amino compounds, catalysts, and dehydrated dimethylformamide (DMF) to form a mixture and react with one another. Then by purification and recrystallization, the anti-cancer compounds are obtained. The anti-cancer compounds of the present invention are compounds with whole new structure that overcome serious cardiac toxicity of the conventional anti-cancer drug-doxorubincin. | 2010-06-10 |
20100145081 | PROCESS FOR PRODUCING PROPYLENE OXIDE - A process for producing propylene oxide, which comprises supplying an organic peroxide and propylene to an epoxidation reactor in which a solid catalyst is packed thereby continuously producing propylene oxide through epoxidation reaction, wherein said process comprises cooling at least a part of the propylene before supplying to separate and remove water contained in the propylene, and supplying the propylene in which water has been separated and removed to the epoxidation reactor. | 2010-06-10 |
20100145086 | Synthesis of Terminal Alkenes From Internal Alkenes Via Olefin Metathesis - This disclosure relates generally to olefin metathesis, and more particularly relates to the synthesis of terminal alkenes from internal alkenes using a cross-metathesis reaction catalyzed by an olefin metathesis catalyst. According to one aspect, for example, a method is provided for synthesizing a terminal olefin, the method comprising contacting, in the presence of a ruthenium alkylidene metathesis catalyst, an olefinic substrate comprised of at least one internal olefin with a cross metathesis partner comprised of an alpha olefinic reactant, under reaction conditions effective to allow cross-metathesis to occur, wherein the reaction conditions include a reaction temperature of at least 35° C. The methods, compositions, reactions and reaction systems herein disclosed have utility in the fields of catalysis, organic synthesis, and industrial chemistry. | 2010-06-10 |
20100145087 | IRON(II) CATALYSTS CONTAINING DIIMINO-DIPHOSPHINE TETRADENTATE LIGANDS AND THEIR SYNTHESIS - New hexa-coordinate iron (II) complexes comprising compounds of formula (I) are described. These compounds comprise a tetradentate ligand with donor atoms comprising nitrogen and phosphorus. These complexes are shown for the first time to be useful catalysts for the hydrogenation of ketones, aldehydes, or imines to produce alcohols or amines, and the asymmetric hydrogenation of prochiral ketones or imines to produce non-racemic alcohols or amines. The source of the hydrogen can be hydrogen gas or a hydrogen-donating molecule such as isopropanol or hydrogen-donating mixture such as formic acid and an amine depending on the structure of the catalyst. In certain embodiments, the axial ligands on the catalyst comprise organonitrile ligands, carbonyl ligands, isonitrile ligands, or combinations thereof. The catalysts and the preparation thereof are disclosed. A reaction using phosphine and diamine precursors that is templated by the iron ion is the preferred route to the catalysts. | 2010-06-10 |
20100145088 | POLY-HALOGENATED TRIAZAPENTADIENE COMPOSITIONS - A new class of fluorinated or polyhalogenated triazepentadienes are disclosed. The synthesized triazapentadienes are thermally stable, soluble in typical solvents and have several metal binding sites for complexation with metal ions. The compounds are prepared as colorless crystalline solids. Synthesis takes advantage of a reaction with triethylamine. Synthesized triazapentadienes (with and without complexed metals) inhibit bacterial growth of both Gram positive and Gram-negative bacteria. | 2010-06-10 |
20100145090 | PROCESS FOR THE PREPARATION OF PROTECTED L ALANINE DERIVATIVES - The present invention is directed to a novel process for the preparation of protected L-alanine derivatives, useful as intermediates in the synthesis of compounds useful as mu/delta opioid modulators. | 2010-06-10 |
20100145093 | Manufacture of Hydrofluoroalkanesulfonic Acids - A process for manufacture of hydrofluoroalkanesulfonic acid with at least one hydrogen bonded to the carbon atom adjacent to the carbon atom bonded to the sulfonic acid group comprising: contacting a fluoroolefin with sulfite in an aqueous solution adjusted to about pH 4 to pH 12; removing water from the solution to form a solid; directly treating the solid with oleum; and distilling the hydrofluoroalkanesulfonic acid therefrom. Also a process for manufacture of potassium hydrofluoroalkanesulfonate in high purity is described. | 2010-06-10 |
20100145095 | OPTIMIZED LIQUID-PHASE OXIDATION - Disclosed is an optimized process and apparatus for more efficiently and economically carrying out the liquid-phase oxidation of an oxidizable compound. Such liquid-phase oxidation is carried out in a bubble column reactor that provides for a highly efficient reaction at relatively low temperatures. When the oxidized compound is para-xylene and the product from the oxidation reaction is crude terephthalic acid (CTA), such CTA product can be purified and separated by more economical techniques than could be employed if the CTA were formed by a conventional high-temperature oxidation process. | 2010-06-10 |
20100145096 | Process for Recovery and Purification of Lactic Acid - The present invention relates to a process for recovery and purification of lactic acid from a fermentation broth containing lactic acid. The process comprises subjecting the fermentation broth to ultrafiltration and/or microfiltration to form a first permeate, concentrating the first permeate to form concentrated broth, subjecting the concentrated broth to supported liquid membrane for extraction of lactic acid into a separate stream, subjecting the extracted lactic acid solution to activated carbon for removal of colour, subjecting the extracted lactic acid solution to cation exchange resin for deminerization, subjecting the extracted lactic acid solution to anion exchange resin for removal of anionic impurities and concentrating the extracted lactic acid solution to desired concentration. The supported liquid membrane of the present invention contains an organic layer that comprises a earner, a co-extractant, a diluent and a stabilizer. | 2010-06-10 |
20100145099 | NOVEL POLYMORPHIC FORMS OF MILNACIPRAN HYDROCHLORIDE - The present invention relates to polymorphic forms of milnacipran hydrochloride. The polymorphic forms are designated as Form (I), Form (II), Form (III), Form (IV) and Form V of milnacipran hydrochloride. The present invention also relates to processes for the preparation of the polymorphic forms. | 2010-06-10 |
20100145103 | METHOD FOR PURIFYING ACETONE - A method for purifying a crude acetone raw material containing low molecular weight impurities using three columns in sequence is disclosed. The method comprises the steps of feeding the crude acetone raw material into a first column; adding an alkaline reagent and an oxidative reagent into the first column; feeding the first bottom fraction to a second rectification column; optionally adding an alkaline reagent to the second column above the charge point of the bottom fraction; separating a purified acetone from the high molecular weight impurities and removing the purified acetone as a top fraction by distillation in the second column, thereby forming a second bottom fraction comprising an acetone mixture comprising high molecular weight impurities; feeding the second bottom fraction comprising the acetone mixture to a third rectification column; removing a top fraction from the third column; and returning the top fraction removed from the third column to the first column, wherein the second rectification column is operated at atmospheric pressure, and wherein the purified acetone has an acetaldehyde level of less than 5 ppm and a KT-Test time of greater than 11 hours, as measured by the SABIC KT-Test method. | 2010-06-10 |
20100145104 | Reactor Panel for Catalytic Processes - Modular reactor panel ( | 2010-06-10 |
20100145106 | PRODUCTION PROCESS OF NUCLEUS-HALOGENATED METHYLBENZYL ALCOHOL - The present invention provides an industrially advantageous process for preparing nuclear halogenated methylbenzyl alcohol which is a useful substance as a raw material, an intermediate for manufacturing medicines, agricultural chemicals, etc. The process of the present invention for preparing nucleus-halogenated methylbenzyl alcohol represented by the following formula (II) comprises hydrogenating nucleus-halogenated benzene carbaldehyde represented by the following formula (I); wherein m is an integer of 0 to 3, and n is an integer of 1 to 4, with the proviso that m+n is an integer of 1 to 4, wherein m and n are the same as those in the formula (I). | 2010-06-10 |
20100145107 | NOVEL PROPANOL AND RELATED COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS - The present invention a method of improving, enhancing or modifying a fragrance formulation through the addition of an olfactory acceptable amount of a compound of formula: | 2010-06-10 |
20100145108 | Method for Purifying Product Mixtures From Transesterification Reactions - The invention relates to an industrial process for purifying the product mixture of a transesterification reaction with a polar, electrolyte-containing organic phase, in which the electrolytes are removed from the permeating polar organic phase by means of a nanofiltration step. | 2010-06-10 |
20100145121 | SYNTHESIS OF PROPYLBENZENE FROM TOLUENE AND ETHYLENE - Methods are provided for producing alkylbenzenes, such as propylbenzene, from aromatics, such as toluene, and alkenes, such as ethylene. Such methods comprise combining the toluene with about 100 ppm to about 350 ppm water and alkali metal catalyst, activating the catalyst at about 18O° C. to about 220° C., adding the ethylene and conducting the synthesis reaction at about 130° C. to about 15O° C. | 2010-06-10 |
20100145123 | Olefin Upgrading Process - A process for the use in the oligomerization of olefins is presented. The process produces a gasoline boiling range product having a high research octane number and almost no aromatics content. The process utilizes a solid catalyst comprising a zeolite that is treated with a phosphorous containing reagent to generate a catalyst having phosphorous content between 0.5 and 15 wt %. | 2010-06-10 |
20100145126 | Process of Producing Olefins - A process of producing olefins by a metathesis reaction in a practical low temperature range by improving the reactivity of the catalyst is provided. | 2010-06-10 |
20100145127 | CATALYTIC COMPOSITION FOR PRODUCING OLEFINS BY CATALYTIC CRACKING - A catalyst composition comprising on weight basis the following components: a) 30 to 99.5% of at least one intergrowth molecular sieve; b) 0 to 20% of a rare earth element or oxides thereof; c) 0 to 10% of at least one element from Group VA of the Periodic Table or oxides thereof; d) 0 to 10% of at least one element from Group IIIA of the Periodic Table or oxides thereof; e) 0 to 20% of at least one element from Group IB or IIB of the Periodic Table or oxides thereof; f) 0 to 20% of at least one element from Group IA or IIA of the Periodic Table or oxides thereof; and g) 0 to 65% of a binder, wherein the components b), c), d), e) and f) are supported on the component a), and contents of at least two of the components b), c), d), e) and f) are larger than zero, is described. A process for preparing said catalyst composition and a process for the production of olefins via catalytic cracking by using said catalyst composition are also described. | 2010-06-10 |
20100145128 | C7 ISOMERISATION WITH REACTIVE DISTILLATION - Process for isomerising a hydrocarbon feed containing at least C | 2010-06-10 |
20100145129 | EXTRACTION METHODS AND APPARATUS - The present invention relates to hydrocarbon extraction method and apparatus therefor. | 2010-06-10 |
20100145162 | SURGICAL METHOD FOR IMPLANTING A HOUSING-INTERFACE ASSEMBLY IN A BONE WALL - The invention relates to surgical method for positioning an extraoral bone-anchored implant device in a receiving bone site of a patient, said patient being a human being or an animal, comprising the following successive steps:
| 2010-06-10 |
20100145166 | Integrated Instrumentation System and Method for Assessing Feeding Readiness and Competence in Preterm Infants - An objective, automated approach for the detection and identification of the suck, swallow and breathe parameters, which approach is vital for successful feeding in preterm infants during bottle feeding. An instrumentation system measures and processes of suck, swallow, and breathe waveforms. The analog signals are digitized by analog-to-digital (A/D) converters. A robust method based on correlation techniques and matched filters is used to detect and identify individual occurrences of suck, swallow and breathe. The results of the correlation method results in an occurrence matrix which contains the start time of the detected event (suck, swallow and/or breathe), the correlation coefficient, or probability of certainty and duration of the suspected event. The occurrence matrix is then used as a measure of coordination of suck, swallow and breathe to determine feeding readiness and competence. | 2010-06-10 |
20100145169 | METHODS AND SYSTEMS FOR DETECTING A CONDITION OF COMPARTMENT SYNDROME - Methods and systems for detecting and alerting one to a condition of Compartment Syndrome provide for determining concentration data of biochemical compounds in tissues, preferably at a shallow depth beneath the skin; analysing the concentration data to detect a condition of Compartment Syndrome; and triggering an alarm if a condition of Compartment Syndrome is detected. The concentration of biochemical compounds may be measured using Near Infrared Spectroscopy. The biochemical compounds may comprise at least one compound from the group consisting of Hemoglobin, Oxygenated Hemoglobin, Cytochromes and Myoglobin. | 2010-06-10 |
20100145170 | Small Animal Pulse Oximeter User Interface - A user interface for a pulse oximetry device that calculates physiologic parameters of a subject including at least a subject's heart rate and S | 2010-06-10 |
20100145171 | APPARATUS FOR MEASURING MOTION NOISE ROBUST PULSE WAVE AND METHOD THEREOF - Provided are a method of measuring the pulse wave at the back of a wrist, etc. where measurement of the pulse wave is difficult so as to prevent a user to feel inconvenience in a mobile environment and a method of detecting the pulse wave at a write portion or at the back of the wrist which has comparatively weak restraint force in a human body by recovering an original signal with comparatively minimum errors so as to be robust to motion noise according to motion of the wrist. | 2010-06-10 |
20100145173 | SYSTEM AND METHOD FOR CREATING A PERSONALIZED TOOL PREDICTING A TIME COURSE OF BLOOD GLUCOSE AFFECT IN DIABETES MELLITUS - A system and method for establishing a tool of blood glucose change for diabetes mellitus management in an individual patient is provided. Factors specific to a diabetic patient are determined. An insulin sensitivity for an insulin preparation for treatment of diabetes mellitus is identified. A carbohydrate sensitivity for a known quantity of carbohydrate is identified, which is measured postprandial after a fixed time period. A management tool for the diabetic patient is generated. A time course for a dose of the insulin preparation with an amplitude of change proportioned to the insulin sensitivity is mapped. A time course for an amount of carbohydrate with an amplitude of change proportioned to the carbohydrate sensitivity is mapped. The management tool is calibrated by aggregating feedback from testing of blood glucose into at least one of the insulin and the carbohydrate sensitivities. | 2010-06-10 |
20100145174 | System And Method For Providing A Personalized Tool For Estimating Glycated Hemoglobin - A system and method for providing a personalized tool for estimating glycated hemoglobin is provided. An electronically-stored history of empirically measured glucose levels for a patient is maintained over a set period of time in order of increasing age. A decay factor is applied to each of the measured glucose levels. The measured glucose levels are aggregated and scaled as decayed into an estimate of glycated hemoglobin for the time period. The glycated hemoglobin estimate is displayed to the patient. | 2010-06-10 |
20100145176 | Universal Electrode Array for Monitoring Brain Activity - Methods of monitoring brain activity signals in a patient are described, including the steps of identifying a lobe or lobes of the patient's brain in which the patient's seizures originate; selecting an electrode array from a plurality of predetermined dispersed electrode patterns based on the identified lobe or lobes of the brain; implanting the electrode array within the patient's cranium to place the electrodes in contact with the identified lobe or lobes of the brain; and coupling the electrodes to an seizure advisory system. Also described is a seizure advisory system that includes an electrode array having fewer than 32 electrodes in a predetermined dispersed radial pattern, adapted to be implanted through a single opening in the skull, and to be deployed in the predetermined dispersed radial pattern to detect a brain activity signal. The system also includes a communication assembly and an external assembly. | 2010-06-10 |
20100145178 | NERVE MONITORING DEVICE - A nerve monitoring device is provided that includes a cannula and a sensor for monitoring a nerve. The device can be inserted into an internal body space at a desired depth of insertion and at a desired rotational orientation to monitor the activity of the nerve and/or an associated muscle(s). At least one of the cannula, the sensor and a sensor support element can be configured to enhance desired contact between the sensor and anatomic features, such as muscles, nerves or tissue, within the body space in an atraumatic manner. At least one of the sensor, cannula and support element can be reconfigurable from a first configuration to a different second configuration, where the second configuration conforms to the anatomical geometry of at least a portion of the body space so that the sensor satisfactorily contacts the target muscle(s) and/or nerve to monitor the same. | 2010-06-10 |
20100145180 | Apparatus for physical measurements of the eye - Utilization of a contact device placed on the eye in order to detect physical and chemical parameters of the body as well as the non-invasive delivery of compounds according to these physical and chemical parameters, with signals being transmitted continuously as electromagnetic waves, radio waves, infrared and the like. One of the parameters to be detected includes non-invasive blood analysis utilizing chemical changes and chemical products that are found in the conjunctiva and in the tear film. A transensor mounted in the contact device laying on the cornea or the surface of the eye is capable of evaluating and measuring physical and chemical parameters in the eye including non-invasive blood analysis. The system utilizes eye lid motion and/or closure of the eye lid to activate a microminiature radio frequency sensitive transensor mounted in the contact device. The signal can be communicated by wires or radio telemetered to an externally placed receiver. The signal can then be processed, analyzed and stored. Several parameters can be detected including a complete non-invasive analysis of blood components, measurement of systemic and ocular blood flow, measurement of heart rate and respiratory rate, tracking operations, detection of ovulation, detection of radiation and drug effects, diagnosis of ocular and systemic disorders and the like. | 2010-06-10 |
20100145183 | IMPLANTABLE MEDICAL DEVICE - An implantable medical device includes a housing and a circuit board provided within the housing. The circuit board includes a plurality of electronic components electrically coupled thereto. At least one non-functional component is provided on the circuit board and formed from a material that has an electromagnetic permeability configured to reduce the amount of image distortion caused by at least one of the plurality of electronic components when the device is subject to a magnetic field during an MRI scan. | 2010-06-10 |
20100145184 | METHOD AND MAGNETIC RESONANCE SYSTEM FOR DETERMINING A CODING FOR A FLOW MEASUREMENT AND FOR IMPLEMENTING A FLOW MEASUREMENT WITH THE CODING - In a method and magnetic resonance system to determine a flow coding for a flow measurement with the magnetic resonance system, in order to determine the optimal flow coding, a flow pre-measurement with multiple different flow codings is conducted within a slice within a body to be examined, each of these codings allowing flow velocities to be detected with a sensitivity dependent on the respective coding. A velocity distribution is generated from the results of this flow pre-measurement by a Fourier transformation. The optimal flow coding for the flow measurement is then determined based on this spectrum. The flow measurement is implemented by determining angiography measurement data of a volume within the body to be examined, determining a vessel, depending on a user input, from the angiography measurement data, automatically determining dimensions and an orientation of the vessel from the angiography measurement data, automatically determining a slice for the flow measurement depending on the dimensions and the orientation, and implementing the flow measurement in the slice with the determined optimal coding. | 2010-06-10 |
20100145186 | IMAGING TECHNIQUE - The present invention relates to a method of characterising lung function in a subject in need of such characterisation. The method comprises performing an imaging technique, on a voxel defined within a lung space of interest. Image data is generated over a time period during which the subject inhales gases with at least two different partial pressures of a paramagnetic gas. A compartmental model algorithm is applied to the image data generated for the voxel to provide information on ventilation, diffusion and perfusion of a lung. The paramagnetic gas is preferably Oxygen. The imaging technique is preferably Oxygen Enhanced Magnetic Resonance Imaging (OE-MRI). | 2010-06-10 |
20100145189 | Intraoral scanner - The invention relates to an intraoral scanner for collecting three-dimensional measured or scanned data of the jaw or teeth, which accommodates a scanning unit in a front region leading into the oral region and which at this front region also accommodates an air delivery device through which pressurized air may be locally supplied in the oral region. | 2010-06-10 |
20100145190 | Traveling-Wave Antenna - Embodiments of endfire aperture-based traveling-wave antennas are described. For example, an embodiment, including a Vivaldi antenna, may have a director incorporated into the aperture region of the antenna to provide enhanced radiation directivity. The director may be a shaped dielectric that interacts with an electromagnetic field to reduce the divergence of the resultant beam as it exits the antenna. Additional dielectric substrate layers may be stacked on both sides of the antenna in order to balance the dielectric loading between the different conductors. The dielectric substrates may also eliminate contact between the antenna metallization and the lossy environment. Certain disclosed Vivaldi antennas may be used in tissue screening applications. | 2010-06-10 |
20100145203 | MUSIC SELECTING SYSTEM AND METHOD THEREOF - The present invention relates to a music selecting system and method, and more particularly, to a technology that suitably determines an emotional quotient of user by preferably using a heart rate and biorhythm of user, and automatically selecting music of specific genre according to the determined emotional quotient, a current time and an age. | 2010-06-10 |
20100145205 | ANALYZING ALTERNANS FROM MEASUREMENTS OF AN AMBULATORY ELECTROCARDIOGRAPHY DEVICE - Cardiac signal data of heart beats measured with an ambulatory electrocardiography device is accessed. The cardiac signal data is segmented into cardiac signal data segments such that each cardiac signal data segment includes cardiac signal data of sequential heart beats. Whether alternans is present in the cardiac signal data segment is determined for each of multiple cardiac signal data segments. Characteristics of the alternans is determined by analyzing cardiac signal data segments for which alternans is determined to be present or by analyzing characteristics of cardiac signal data segments for which alternans is determined to be present. | 2010-06-10 |
20100145209 | APPARATUS FOR MEASURING AMOUNT OF EXERCISE, SYSTEM FOR MEASURING AMOUNT OF EXERCISE, AND METHOD FOR MEASURING AMOUNT OF EXERCISE - An apparatus for measuring the amount of exercise, a system for measuring the amount of exercise, and a method for measuring the amount of exercise are disclosed. The apparatus for measuring the amount of exercise includes: an exercise amount measuring unit that measures the amount of exercise of a user; a controller that generates information about exercise of each period from the amounts of exercise of the user measured at every predefined period; a memory unit that sequentially stores the information about the exercise of each period; and a communication unit that transmits the stored information about the exercise of each period to the exterior. | 2010-06-10 |
20100145210 | Multi parametric classification of cardiovascular sounds - The present application relates to a method for classifying a cardiovascular sound recorded from a living subject. The method comprises the step of extracting at least two signal parameters ( | 2010-06-10 |
20100145232 | METHODS AND APPARATUSES FOR CORRECTING SPORT POSTURES CAPTURED BY A DIGITAL IMAGE PROCESSING APPARATUS - A sport posture correcting apparatus including a digital image processing apparatus configured to generate a series of image frames. The sport posture correcting apparatus may include a digital signal processing unit configured to set a region in one of the series of generated image frames. The digital signal processing unit may be configured to trace the set region in the series of generated frames to generate a tracing result. The digital signal processing unit may be configured to display the tracing result. | 2010-06-10 |
20100145235 | Device for fixing at least one fibrous strip to a body part, and method for the production of said strip - A device (V) for fixing at least one fibrous strip (FB) to a body part (K), wherein the fibrous strip comprises at least one fibre (F) embodied as a fibre-optic bending sensor, has at least one fixing unit (BE) which respectively has (a) a fixing part (BM) for applying part of the fibrous strip to the body part, and (b) at least one fixing loop (BS) for guiding the fibrous strip along an axis of a three-dimensional space. The fixing loop can be fixed to the body part. | 2010-06-10 |
20100145236 | System and Apparatus for Continuous Monitoring of Movement Disorders - Disclosed embodiments include a complete system and platform which allows for continuous monitoring of movement disorders during normal daily activities in the clinic, home, and other normal daily environments. The system comprises: 1) a wearable apparatus for continuous monitoring of movement disorders, 2) a docking station, 3) a web server, and 4) methods for statistical analysis that generate movement impairment measures. Disclosed embodiments include a wearable movement monitoring apparatus comprising of (a) a sensor module including a plurality of low power micro-electromechanical systems kinematics sensors; (b) a microprocessor module including a low power microcontroller configured for device control, device status, and device communication; (c) a data storage module including a solid state local storage medium; (d) a wireless communication module including a low power surface mount transceiver and an integrated antenna; and (e) a power and docking module including a battery, an energy charging regulator circuit, and a docking connector. | 2010-06-10 |
20100145238 | ORTHESIS - The invention relates to an orthesis for controlling the angle of a limb relative to a second body part to which the limb is connected via a joint such as a hip, elbow or shoulder, which orthesis comprises:—a first arm rotatably, around a rotation point, connected to the second body part;—a second arm fixedly arranged to the lim; and—guide means for providing at least a two dimensional free translation of the second arm relative to the first arm, while maintaining both arms parallel. | 2010-06-10 |
20100145240 | COMBINED MASSAGE AND EXERCISE DEVICE - A combined massage and exercise device includes a frame, substantially parallel, spaced-apart rollers receivable within the frame, in which each roller is rotatable around a respective roller axis intersecting a side of the frame, and a spring that provides resistance to rotational motion about the roller axis of at least one of the rollers. | 2010-06-10 |
20100145273 | Method for producing a heating device having a heating profile for medical instruments and a heating device produced by that method - A method for producing a temperature control means ( | 2010-06-10 |
20100145274 | LIQUID PHARMACEUTICAL IDENTITY AND QUANTITY MARKING - Rendering conspicuous liquid medicaments which are conventionally supplied as colorless liquids. A coloring agent may be added to the conventionally colorless liquid. Where different liquid medicaments are supplied, coloring agents of different hues may be added to the respective different liquid medicaments. A syringe for dispensing liquids may be provided with a temperature responsive device which changes in appearance so as to indicate level of liquid medicament loaded thereinto, responsively to temperature of the liquid medicament. | 2010-06-10 |
20100145275 | Device for Automatic Delivery of Successive Doses of Product - The invention relates to a device ( | 2010-06-10 |
20100145276 | PORTABLE INFUSION DEVICE WITH MEANS FOR MONITORING AND CONTROLLING FLUID DELIVERY | 2010-06-10 |
20100145280 | Catheter clip for securing a catheter hub to a patient - A spring-loaded clip for removably attaching a catheter hub to the skin of a patient. The clip includes first and second needle members pivotably connected on a common axis and closable with their respective arcuate needle elements interlocked within the skin of a patient. A bias spring urges the first and second needle elements into a preferred position, preferably the closed position. Each needle member includes a lever for use in opening and closing the clip and also includes a grasping element for capturing a catheter hub as the clip closes. Preferably, the needle elements are curved through about 120°, are sharpened to a point at a first end, and are joined to a pivot element at the opposite end. No separate conventional suturing of a catheter hub to a patient is required. | 2010-06-10 |
20100145283 | APPLICATOR - An applicator, for example an injector ( | 2010-06-10 |
20100145284 | NEEDLE-EQUIPPED SYRINGE BARREL NEEDLE-EQUIPPED SYRINGE, AND MOLD AND METHOD FOR MOLDING SAME - There are provided a needle-equipped syringe barrel and a needle-equipped syringe in which a needle is suitably fixed to a syringe nozzle, and a mold and a method for molding thereof. A metal needle | 2010-06-10 |
20100145285 | MULTI-LUMEN CATHETER CONFIGURATION - A multi-lumen catheter for use in the extracorporeal treatment of bodily fluids comprises a tubular catheter body having a first septum extending along its length, and having a withdrawal port and an infusion port. First and second withdrawal lumens are disposed on one side of the septum for transporting fluids withdrawn from a body vessel through the withdrawal port to an extracorporeal treatment unit, such as a dialyzer. An infusion lumen is disposed on the other side of the septum for infusion of treated fluids from the dialyzer through the infusion port into the vessel. The catheter body has a second septum extending along a length of the first septum. A proximal portion of the second septum separates the first and second withdrawal lumens, and a distal portion of the second septum extends distal to the withdrawal port. The distal portion tapers to a termination point along the length of the first septum length, for easing entry of the catheter into the vessel. | 2010-06-10 |
20100145286 | LAYERED NON-FOULING, ANTIMICROBIAL ANTITHROMBOGENIC COATINGS - Substrates, optionally coated with an undercoating, having grafted thereto one or more non-fouling materials are described herein. The non-fouling, polymeric material can be grafted to a variety of functionalized substrate materials, particularly polymeric substrates and/or polymeric undercoatings immobilized on a substrate. The compositions described herein are highly resistant protein absorption, particularly in complex media and retain a high degree of non-fouling activity over long periods of time. The compositions described herein may also demonstrate antimicrobial and/or anti-thrombogenic activity. The non-fouling material can be grafted to a functionalized substrate, or optionally from an undercoating on the substrate, preferably without significantly affecting the mechanical and/or physical properties of the substrate material | 2010-06-10 |