| 23rd week of 2016 patent applcation highlights part 11 |
| Patent application number | Title | Published |
|---|
| 20160158418 | BONDED ALUMINA COATING FOR STAINLESS STEEL - A method for manufacturing an alumina-based layer structure having transition regions between layers is disclosed. The method may include ion milling a stainless steel structure surface to partially reduce a metal oxide layer from, and create an exposed portion of, the surface. The method may include oxidizing the exposed portion of the surface to form a crystallized metal oxide bonding layer, growing a crystallized alumina layer onto the metal oxide bonding layer, and diffusing metal from the surface into the crystallized alumina layer, to form a graded aluminate spinel layer. The method may include forming a first transition region from the graded aluminate spinel layer to a crystalline alumina layer, growing the crystalline alumina layer from the first transition region, forming a second transition region from the crystalline alumina layer to an amorphous alumina layer, and growing the amorphous alumina layer from the second transition region. | 2016-06-09 |
| 20160158419 | MULTI-LAYER BIODEGRADABLE DEVICE HAVING ADJUSTABLE DRUG RELEASE PROFILE - Methods and apparatus for a biodegradable multi-layer device suitable for medical applications are provided, wherein the device is formed from multiple film-layers configured to have different characteristics from one another such as different release profiles for therapeutic agents, adhesive properties, stiffness properties, and solubility properties. The film-layers may include a solid fibrinogen component. A device having multiple film-layers may take a non-adherent form during delivery to a target location within or on tissue, and thereafter may be exposed to moisture to take an adherent form on the tissue. The device may include a number of additives, including materials to improve the mechanical properties of the device, or one or more therapeutic or contrast agents. | 2016-06-09 |
| 20160158420 | COATINGS FORMED FROM STIMULUS-SENSITIVE MATERIAL - A coating comprising a stimulus-responsive material and a bioactive agent for controlled release of the bioactive agent and methods of making and using the same are disclosed. | 2016-06-09 |
| 20160158421 | COMPOSITIONS AND METHODS FOR COATING IMPLANT SURFACES TO INHIBIT SURGICAL INFECTIONS - Infection-inhibiting compositions suitable for coating surfaces of implantable medical implants, including compositions and devices for coating medical devices in the operating room prior to implantation in a patient. Methods for inhibiting infection at the site of implantation of an orthopedic device in a human or animal subject, comprise rubbing a surface of the device, prior to implantation, with an infection-inhibiting composition having a waxy matrix comprising an infection-inhibiting material selected from the group consisting of a lipid, an antimicrobial agent, and mixtures thereof, wherein a thin layer of the infection-inhibiting material is deposited on the surface of the device. Medical implants which may be treated in the methods of this technology include orthopedic implants. Lipids include long-chain diacylglycerides or triacylglycerides, which may be saturated or unsaturated, such as lecithin or a purified form of phosphatidylcholine. | 2016-06-09 |
| 20160158422 | BIODEGRADABLE SUPPORTING DEVICE - A biodegradable in vivo supporting device is disclosed. The in vivo supporting device comprises a biodegradable metal scaffold and a biodegradable polymer coating covering at least a portion of the biodegradable metal scaffold, wherein the biodegradable polymer coating has a degradation rate that is faster than the degradation rate of the biodegradable metal scaffold. | 2016-06-09 |
| 20160158423 | DEVICES AND METHODS FOR CLEANING CONTAMINATED BODY CAVITIES - An apparatus includes a housing, a first cannula, and a second cannula. The housing defines an inner volume having a first portion in fluid communication with a first set of openings, and a second portion in fluid communication with a second set of openings and fluidically isolated from the first portion. The first cannula has a proximal end portion fluidically couplable to a vacuum source and a distal end portion coupled to the housing such that the first portion of the inner volume and a lumen defined by the first cannula fluidically couple the first openings to the vacuum source. The second cannula has a proximal end portion fluidically couplable to a fluid source and a distal end portion coupled to the housing such that the second portion of the inner volume and a lumen defined by the second cannula fluidically couple the second openings to the fluid source. | 2016-06-09 |
| 20160158424 | HIDDEN AND WEARABLE BREAST-MILK PUMPING SYSTEM - A hidden and wearable breast-milk pumping system includes a pumping unit, a collecting unit and a wireless control unit. The pumping unit includes a pumping module and an attaching layer configured for attaching to a breast. The pumping module includes a nozzle, a pumping chamber, a pumping tube connected to the pumping chamber and a milk tube. The nozzle covers the breast and connects the pumping chamber connected between the nozzle and the milk tube. The collecting unit is connected to the milk tube to collect and store the breast milk in the milk tube. The wireless-control unit includes a control module, a vacuum pump and a wireless module. The vacuum pump is connected to the pumping tube. The control module controls the vacuum pump according to a control signal received by the wireless module from a remote device. | 2016-06-09 |
| 20160158425 | APPARATUS FOR BLOOD CONCENTRATION - A disposable blood transfer conduit is used in association with a pump drive unit, a blood collection vessel and a blood concentration device. The blood transfer conduit comprises a blood transfer tube ( | 2016-06-09 |
| 20160158426 | SKIN INTERFACE DEVICE FOR CARDIAC ASSIST DEVICE - A skin interface device (“SID”) for a cardiac assist device, including a SID cap having a first housing, an annular sleeve, and a first annular winding disposed over said annular sleeve. The SID further includes a SID base having a second housing formed to include a tubular portion, a cylindrical member disposed in said tubular portion, and a second annular winding disposed around said cylindrical member. The SID cap is configured to be rotationally attached to said SID base. When the SID cap is attached to the SID base, the second annular winding is disposed within the first annular winding, and the relative positions of the first annular winding and the second annular winding are fixed both laterally and vertically. | 2016-06-09 |
| 20160158427 | SELF CALIBRATING BLOOD CHAMBER - An optical blood monitoring system and corresponding method avoid the need to obtain a precise intensity value of the light impinging upon the measured blood layer during the analysis. The system is operated to determine at least two optical measurements through blood layers of different thickness but otherwise substantially identical systems. Due to the equivalence of the systems, the two measurements can be compared so that the bulk extinction coefficient of the blood can be calculated based only on the known blood layer thicknesses and the two measurements. Reliable measurements of various blood parameters can thereby be determined without certain calibration steps. | 2016-06-09 |
| 20160158428 | SYSTEMS AND METHODS FOR INCREASING CONVECTIVE CLEARANCE OF UNDESIRED PARTICLES IN A MICROFLUIDIC DEVICE - A microfluidic device for increasing convective clearance of particles from a fluid is provided. In some implementations, described herein the microfluidic device includes multiple layers that each define infusate, blood, and filtrate channels. Each of the channels have a pressure profile. The device can also include one or more pressure control features. The pressure control feature controls a difference between the pressure profiles along a length of the device. For example, the pressure control feature can control the difference between the pressure profile of the filtrate channel and the pressure profile of the blood channel. In some implementations, the pressure control feature controls the pressure difference between two channels such that the difference varies along the length of the channels by less than 50% of the pressure difference between the channels at the channels' inlets. | 2016-06-09 |
| 20160158429 | HYPERTHERMIC BODY FLUID TREATMENT SYSTEM AND METHOD FOR THE SAME - A method for hyperthermic treatment of body fluid includes diverting at least a portion of a body fluid through a body fluid inlet from a body. A viral load of a pathogen is measured in the body fluid, and a target treatment temperature is determined based on the measured viral load. The body fluid is heated to the target treatment temperature to decrease the viral load in the body fluid. The body fluid is returned to the body after hyperthermic treating through a body fluid outlet. Hyperthermic treating of the body fluid is repeated with another portion of body fluid diverted through the hyperthermic treatment assembly. | 2016-06-09 |
| 20160158430 | METHOD FOR CONTROLLING A BLOOD TREATMENT APPARATUS AND APPARATUSES - The present invention relates to a method for controlling a blood treatment apparatus, with the conveying of blood using a blood pump, with the patient venous tubing clamp closed, until a predetermined volume of fluid has passed out of the blood tubing set through the membrane and into the dialysis fluid chamber. It also relates to a control and regulating apparatus and a treatment apparatus. It further relates to a computer program, a computer program product and a digital storage medium. | 2016-06-09 |
| 20160158431 | FILTERING OF PRESSURE SIGNALS FOR SUPPRESSION OF PERIODIC TABLES - A filtering device receives a pressure signal (P) from a pressure sensor in a fluid containing system, the pressure signal (P) comprising first pulses originating from a first periodic pulse generator and second pulses. The device acquires a reference signal which is indicative of a current operating frequency of the first periodic pulse generator. The device identifies, based on the reference signal, a plurality of harmonics ( | 2016-06-09 |
| 20160158432 | DIALYSIS VALVE AND METHOD - A dialysis valve includes a tube attached between an artery and a vein which, when elongated, simultaneously narrows in diameter at at least one location. The narrowed portion of the tube decreases the volume and velocity between the arterial and venous side of the patient to prevent damage or intimal hyperplasia on the venous side between dialysis treatments. When the valve is opened for dialysis, an unrestricted blood flow exists between the arterial and venous side, permitting a controlled, open blood flow during dialysis. | 2016-06-09 |
| 20160158433 | METHOD OF MONITORING AN EXTRACORPOREAL BLOOD TREATMENT AND APPARATUS FOR CARRYING OUT SAID METHOD - The invention relates to a method of monitoring an extracorporeal blood treatment apparatus having an extracorporeal blood circuit and in particular a venous needle disconnection by means of pressure pulse measurement at the extracorporeal blood circuit. The invention further relates to an apparatus for carrying out a monitoring method and to a blood treatment apparatus which includes a corresponding monitoring apparatus. | 2016-06-09 |
| 20160158434 | POWER INJECTOR WITH DECAY CONSTANT FUNCTIONALITY - A power injector is disclosed having power injector control logic, which in turn includes a decay constant cross-reference, for instance in the form of a data structure. Flow rate decay constant information may be stored by the decay constant cross-reference. A decay constant, which may be used by the power injector to generate an exponentially decaying flow rate for an injection, may be stored in the decay constant cross-reference in conjunction with a particular imaging unit. The decay constant cross-reference may be searched by entering a model or module number of an imaging unit to identify the corresponding flow rate decay constant to be used by the power injector. | 2016-06-09 |
| 20160158435 | FLOW PATHWAY SUBASSEMBLY - A flow pathway subassembly ( | 2016-06-09 |
| 20160158436 | TUBELESS FLUID DELIVERY DEVICE - A catheter-free drug fluid infusion device, comprising a controller ( | 2016-06-09 |
| 20160158437 | Apparatus and Method for Infusing Fluid Through a Tube by Appropriately Heating the Tube - A peristaltic pump disclosed herein includes a raceway, a plunger, a motor, and a heater. The raceway is configured to retain a tube (e.g., an IV tube). The plunger acts on the tube disposed within the raceway. The motor engages the plunger to actuate the plunger. The heater is disposed in thermal-conductive contact with the tube. That is, the heater, either through direct or indirect application, heats the tube. | 2016-06-09 |
| 20160158438 | ADVANCE DIAGNOSIS OF INFUSION DEVICE OPERATING MODE VIABILITY - Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device to deliver fluid to a user in accordance with an operating mode involves obtaining operational information pertaining to one or more prior instances of the operating mode, obtaining status information pertaining to the infusion device, and determining a diagnosis time based at least in part on the operational information. The diagnosis time is prior to a subsequent instance of the operating mode. At the diagnosis time, the method automatically determines the viability of the subsequent instance of the operating mode based at least in part on the status information and automatically generates a notification indicative of a recommended action for the user based at least in part on the viability. | 2016-06-09 |
| 20160158439 | DEVICE AND METHODS FOR TRANSVASCULAR TUMOR EMBOLIZATION WITH INTEGRATED FLOW REGULATION - A catheter assembly may be provided with a catheter body and an inflatable balloon. The catheter body has a proximal end, a distal end and a balloon inflation lumen. The inflatable balloon is attachable to the distal end of the catheter body. The balloon has an inner surface that at least partially defines an interior volume. The balloon is configured such that the interior volume can be in fluid communication with the inflation lumen of the catheter body to inflate the balloon. The balloon also has a proximal surface and a distal surface. The balloon is provided with a channel that extends through the balloon. The channel is configured to provide fluid communication between the proximal surface of the balloon and the distal surface of the balloon. Other catheter assemblies and methods of use are also disclosed. | 2016-06-09 |
| 20160158440 | Simplified Microplegia Delivery System - Cardioplegia is a mixture of blood and cardioplegic solution administered through the coronary vessels to protect the myocardium during cardiopulmonary bypass procedures. Microplegia describes the use of concentrated cardioplegic solution during cardioplegia delivery in an effort to reduce hemodilution and improve myocardial protection. This new apparatus is designed to deliver concentrated cardioplegic solution during cardioplegia delivery. The apparatus features cost saving opportunities, adaptability to any cardioplegia system, simplified delivery options, and safety options. Cardioplegia flow sensor integration to the apparatus allows for convenient auto start/stop as well continuously updated flow-based delivery of the cardioplegic solution during cardioplegia delivery. | 2016-06-09 |
| 20160158441 | METHODS FOR OPERATING MODE TRANSITIONS AND RELATED INFUSION DEVICES AND SYSTEMS - Infusion systems, infusion devices, and related operating methods are provided. An exemplary method involves operating an infusion device to deliver fluid to a user in accordance with a first operating mode of a plurality of operating modes, obtaining operational information pertaining to the first operating mode, and obtaining clinical information pertaining to the user. A destination operating mode of the plurality of operating modes is determined based at least in part on the operational information and the clinical information, and the infusion device is operated to deliver the fluid in accordance with the destination operating mode in a manner that is influenced by at least a portion of the operational information pertaining to the first operating mode. | 2016-06-09 |
| 20160158442 | Algorithm for Removal of Noise During Administration of Fluid to a Patient - A de-noising algorithm is executed dynamically as data is received to generate and update a set of candidate solutions. Each candidate solution is a representation of the data using one or more line segments, and each line segment is fitted to the data within the time period that the segment spans. During each iteration of the algorithm, one candidate solution is identified as a best solution, and properties of the best solution are utilized to dynamically compute properties of the data. To limit the number of active candidate solutions and the corresponding processing power required to update and evaluate them, candidate solutions that fall too far behind the best candidate solution are eliminated from consideration. The de-noising algorithm finds particular utility in the context of a load cell signal that is representative of a weight of an intravenous fluid container. | 2016-06-09 |
| 20160158443 | HANDHELD DIABETES MANAGER WITH A USER INTERFACE FOR DISPLAYING A STATUS OF AN EXTERNAL MEDICAL DEVICE - A handheld diabetes manager has a graphical user interface for displaying status of an external medical device and includes a port configured to receive a test strip and a blood glucose measurement module. The diabetes manager includes a communications module that selectively communicates via a wireless data link with an external medical device to receive status data pertaining to the operation of the external medical device, and a user interface module in data communication with the blood glucose measurement module and the communications module. The graphical user interface includes a status screen that presents data pertaining to a glucose measure determined by the blood glucose measurement module concurrently with the status data received from the external medical device, such that the status data of the external medical device is presented on the status screen only when the communication module is in data communication with the external medical device. | 2016-06-09 |
| 20160158444 | DEVICE FOR DELIVERING A MEDICAMENT - A device for delivery of medicament, which device comprises an elongated housing; a container mounted within said housing and adapted to contain liquid medicament; a stopper slidably arranged within said container; and actuating means comprising a resilient member, a driving means having one end connected to the stopper and a second end being operably connected to the resilient member, retaining means for releasably retaining said driving means in a first position where said resilient member has an accumulated energy, and activating means operably connected to said retaining means for releasing said driving means to a second position, upon actively operation by an user, such that said accumulated energy is transferred to the driving means for driving the stopper a predetermined distance within the container whereby the medicament within said container is delivered characterized in that the resilient member is a variable force spring adapted for generating a predetermined sequence of at least two different force profiles during the medicament delivery. | 2016-06-09 |
| 20160158445 | DUAL-FUNCTION SPRING - An injection device for dispensing a product, the injection device including a moveable element which is moved for a dispensing operation, a spring, a product container holder and a product container, wherein the spring pushes against the moveable element to move the moveable element to an initial position after the dispensing operation has ended and against the product container to seat the product container in the product container holder. | 2016-06-09 |
| 20160158446 | SYRINGE ASSEMBLY - An insert useful with a dermal filler syringe is provided for facilitating mixing of active agents with dermal fillers being injected into skin. | 2016-06-09 |
| 20160158447 | SYRINGE FOR AND METHOD OF DELIVERING A VOLUME OF SOLUTION WITH GUIDANCE BEARING IN VIEW OF STANDARD AND NON-STANDARD CARPULES - Methods and apparatuses are disclosed with regard to syringe-transfer of a solution or other fluid, optionally with a guidance bearing, within a standard or non-standard carpule, optionally having sealed top ends and measurement gradations, i.e., indicia. One embodiment is a non-standard carpule barrel having a top portion, a bottom portion, and a barrel portion therebetween. The top portion includes an opening for receiving a syringe plunger and at least a first portion for connecting to an upper portion of the syringe. The bottom portion includes another opening capable of holding a bottom end of the carpule, wherein the carpule may be a standard carpule or a non-standard carpule. The barrel portion is located between the top portion and bottom portion, and includes a cradle, which has a length capable of holding a standard or a non-standard carpule, which has a greater width than a standard carpule. | 2016-06-09 |
| 20160158448 | Display Assembly and Dispensing Device - A display assembly is proposed, comprising: a body ( | 2016-06-09 |
| 20160158449 | Syringe with Visually Coded Needle Hub - A medication delivery device included molded cylindrical barrel having visual marks on the surface of the barrel in the axial direction, a plunger seals the distal opening of the cylindrical barrel, a molded needle hub disposed in the proximal opening of the cylindrical barrel for sealing the needle hub to the barrel. A needle is disposed in the needle hub for communicating liquids by operation of the plunger in the axial direction. The circumferential surface on the flange of the needle hub comprises a colored mark that corresponds to a characteristic of the medication delivery device or its contents. | 2016-06-09 |
| 20160158450 | AUTOMATIC INJECTION DEVICES HAVING OVERMOLDED GRIPPING SURFACES - Exemplary embodiments provide automatic injection devices, housing components for automatic injection devices and methods for fabricating the same. An exemplary housing of an automatic injection device may be overmolded with one or more gripping surfaces to facilitate gripping and manipulation of the automatic injection device by a user when performing an injection. In an exemplary embodiment, an overmolded left gripping surface may extend along a left side of the housing and an overmolded right gripping surface may extend along a right side of the housing opposite to the left side. | 2016-06-09 |
| 20160158451 | PRIMING CONFIGURATION FOR A MEDICAL DEVICE AND DRUG DELIVERY DEVICE COMPRISING A PRIMING CONFIGURATION - The priming configuration comprises a piston rod ( | 2016-06-09 |
| 20160158452 | Syringe With Plunger Rod Having a Flexible Portion - A syringe assembly including a plunger rod having a first end, a second end, and a rod portion extending therebetween, wherein at least a portion of the rod portion is flexible is disclosed. The flexible portion of the rod portion allows a stopper to be moved between a first position and a second position within a syringe barrel while the overall length of the syringe assembly remains the same throughout the movement between the first position and the second position. In another embodiment, a syringe assembly including a restraining member adapted to communicate with the flexible portion of the rod portion such that movement of the first end of the plunger rod in a first direction actuates movement of the second end of the plunger rod in a second direction different than the first direction is disclosed. | 2016-06-09 |
| 20160158453 | DRIVE MECHANISM - A drive mechanism ( | 2016-06-09 |
| 20160158454 | DRUG DELIVERY DEVICE - The invention refers to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing ( | 2016-06-09 |
| 20160158455 | Assembly for a Drug Delivery Device and Method of Operating the Same - An assembly for a drug delivery device ( | 2016-06-09 |
| 20160158456 | DRIVE MECHANISM FOR A DELIVERY DEVICE - A drive mechanism for a delivery device is presented. The drive mechanism comprises a housing ( | 2016-06-09 |
| 20160158457 | INJECTOR FOR ADMINISTERING A LIQUID OR PASTY SUBSTANCE, IN PARTICULAR A DRUG - An injector for administering a first and a second liquid or pasty substance, in particular a drug, comprises an outer injector body in which an inner injector body is longitudinally displaceably guided in which a plunger is longitudinally displaceably guided. To improve such an injector, the inner injector body has a cuff which sealingly contacts the inner wall of the outer injector body and which can be flowed around by the second liquid or pasty substance when it is in the end position in the outer injector body. | 2016-06-09 |
| 20160158458 | Safe Injection Device Capable of Locking Needle - An injection needle assembly includes a needle extended from a needle seat and a lockable needle arrangement which includes a locking platform radially extended from the needle seat, a needle enclosure foldably extended from the locking platform for enclosing the needle, and a locker unit including a first locker provided at the locking platform and a second locker provided at the needle enclosure, wherein the first and second lockers are engaged in a non-releasable manner to securely lock up the needle enclosure on the locking platform for ensuring the needle to be enclosed within the needle enclosure. Therefore, after the use of the needle for injection, the needle is enclosed and protected by the needle enclosure for preventing any cross infection. | 2016-06-09 |
| 20160158459 | Frontal Attachment Device for Syringe with Pinch-Activated Retraction - A retractable needle device attachable to the front of a fluid collection or infusion device such as a syringe, the retractable needle device comprising a housing having an engagement member, a slide support surface, a retraction cavity and a first pinch surface; a needle; a needle alignment member comprising a needle tube and a second pinch surface; and a needle retraction mechanism positioned within the needle tube and configured to bias the needle rearwardly; wherein the first and second pinch surfaces are configured so that a pinching force applied to them will cause relative lateral movement between the housing and needle alignment member. This translational movement from an injection position, wherein the needle is aligned with the syringe connector, to a retraction position, wherein the needle is aligned with the retraction cavity, allows the needle retraction mechanism to force the needle into the retraction cavity. | 2016-06-09 |
| 20160158460 | AUTOMATIC INJECTOR WITH NEEDLE COVER - An auto-injector automatically dispenses a predetermined dose of medicament upon activation. The auto-injector includes a needle cover operative to engage an injection site and activate the injector. The needle cover is configured to move from a locked retracted position prior to a medicament dispensing operation to a locked extended position after the medicament dispensing operation. The non-removable needle cover prevents contact with the needle both before and after the medicament dispensing operation. | 2016-06-09 |
| 20160158461 | SYSTEM FOR DETECTING AND REMOVING A GAS BUBBLE FROM A VASCULAR INFUSION LINE - A system for detecting and removing a gas bubble from a vascular infusion line, the system comprising:
| 2016-06-09 |
| 20160158462 | MULTI-STROKE DELIVERY PUMPING MECHANISM FOR A DRUG DELIVERY DEVICE FOR HIGH PRESSURE INJECTIONS - A dual-chambered drug delivery device, comprising a cartridge having a first chamber for storing a medicament, a second chamber in fluid communication with said first chamber, a dose setting member for setting a medicament dose to be injected at an injection site, a piston disposed in said second chamber, an upward stroke of said piston drawing a portion of the medicament dose into said second chamber and a downward stroke of said piston expelling the portion of the medicament dose, a needle communicating with said second chamber for sequentially injecting portions of the medicament dose into the injection site, a drive screw movably connected to said dose setting member such that rotation of said dose setting member moves said drive screw upwardly, and a rack movably connected to said drive screw such that downward movement of said drive screw during the medicament dose injection rotates said rack. | 2016-06-09 |
| 20160158463 | Adhesive and Peripheral Systems and Methods for Medical Devices - A repeater system may control a pump by using a repeater and a user interface. An adhesive patch system may be used for affixing a pump or other object to a human body. Such an adhesive patch system may include two sets of adhesive members, each member including an adhesive material on at least one side so as to attach to the body. The members of the first set are spaced to allow the members of the second set to attach to the body in spaces provided between the members of the first set, and the members of the second set are spaced to allow members of the first set to detach from the body without detaching the members of the second set. Also, fill stations and base stations are provided for personal pump systems. | 2016-06-09 |
| 20160158464 | A MESH FOR USE IN A NEBULISER, AND A METHOD OF MANUFACTURING THE SAME - There is provided a mesh for use in forming droplets of liquid in a nebuliser, the mesh comprising a first portion ( | 2016-06-09 |
| 20160158465 | DISPENSER - A drug or medical treatment dispenser comprises a tube having a plurality of apertures from which a treatment is spayed towards the skin of a person or animal. | 2016-06-09 |
| 20160158466 | REPLACEMENT CARTRIDGE - Embodiments of the present invention relate to an exchangeable cartridge for generating an aerosol with at least one bottom element and with at least one cover element, wherein in the bottom element and/or the cover element a reservoir is formed for a first, in particular liquid, aerosol component, wherein in the exchangeable cartridge a nebulizer nozzle is formed, wherein the bottom element and the cover element are connected to each other by a bayonet catch. | 2016-06-09 |
| 20160158467 | BREATH-ACTUATED NEBULIZER FOR MEDICINE INHALATION - Breath-actuated nebulizers for delivering medicine are provided, including an outlet port; an opening; and a medicine cup coupled to the opening through a venturi tube. The medicine cup receives a medicine to be delivered through the outlet port, and is coupled to the outlet port. Some embodiments include a jet nozzle coupled to a pressurized gas source and protruding into the medicine cup, and a sleeve in the medicine cup fluidically coupling the venturi tube to the medicine cup and forming a capillary volume with the jet nozzle. In some embodiments, a rib supports a diverter disposed above a nozzle tip to form a radial flow of the pressurized gas away from a nozzle axis. Also provided is a method for manufacturing and using the above nebulizer. | 2016-06-09 |
| 20160158468 | SYSTEMS AND METHODS FOR CONDUCTING SMOKE EVACUATION DURING LAPAROSCOPIC SURGICAL PROCEDURES - An insufflation and smoke evacuation system for use during laparoscopic surgical procedures in an abdominal cavity of a patient is disclosed that includes a pump for circulating pressurized gas within the system, and a dual lumen cannula configured to provide access to the abdominal cavity of a patient, which includes a first lumen communicating with a source of insufflation fluid and a second lumen communicating with the pump. | 2016-06-09 |
| 20160158469 | INHALATION MONITORING SYSTEM AND METHOD - An inhalation monitoring system includes an inhaler having a medicament delivery apparatus configured to deliver medicament to a user during an inhalation of the user; inhalation monitoring apparatus, configured to, during the inhalation, gather data for determining a measure of the user's lung function and/or lung health; and a processor configured to receive the data from the inhalation monitoring apparatus and, using the data, determine a measure of the user's lung function and/or lung health. | 2016-06-09 |
| 20160158470 | POWDER INHALER - Powder inhaler, consisting of a base housing ( | 2016-06-09 |
| 20160158471 | INTEGRATION OF GLUCOSE DATA TO ADJUST INHALED INSULIN DOSE - An insulin dispenser receives blood glucose readings wirelessly from a blood glucose monitor, and calculates an insulin dose based on the historical response of the particular patient to prior insulin doses. The insulin dispenser preferably nebulizes an insulin-containing fluid for inhalation by the patient. | 2016-06-09 |
| 20160158472 | Ventilation - There is provided a method of controlling a mechanical ventilator. The method may include the steps of receiving a measurement of transthoracic impedance of a patient obtained during chest compressions, determining a timing for a mechanical ventilator to provide a ventilation based on the measurement of transthoracic impedance, and sending a signal to control the mechanical ventilator based on the determined timing. There is also provided an apparatus for performing the method. | 2016-06-09 |
| 20160158473 | Ventilator circuit stabilizer and method of stabilizing a ventilator - Provided are a device and method for securing the ventilator tubing circuitry to a patient so as to prevent the circuitry from becoming disconnected from the patient or ventilator or becoming entangled, crushed or otherwise made non-functional thereby causing possible harm to the patient. | 2016-06-09 |
| 20160158474 | FACIAL MASK WITH INTERNAL SUPPORT STRUCTURE FOR USE WITH VENTILATION AND POSITIVE AIR PRESSURE SYSTEMS - The present disclosure relates to a positive airway interface system which includes a facial mask having an internal support structure and an external shell disposed over the internal support structure and a plurality of attachment mechanisms provided about an external surface of the external shell. The positive airway interface system can thus be configured to transform a sealing force applied by a strap assembly in a uniform-like manner so as to sealingly engage the facial mask around a user's mouth and nose when a sealing force applied to the attachment mechanisms. | 2016-06-09 |
| 20160158475 | HYBRID POSITIVE AIRWAY INTERFACE SYSTEM FOR USE WITH VENTILATION AND POSITIVE AIR PRESSURE SYSTEMS - The present disclosure relates to a positive airway interface system which includes a mouth interface having an internal support structure and an external shell disposed over the internal support structure and a plurality of attachment mechanisms provided about an external surface of the external shell. The positive airway interface system also includes a nasal interface having a pair of nasal pillows configured to sealingly engage with a user's nares. This positive airway interface system can be configured to transform a tensile sealing force applied by a headgear strap assembly in a uniform-like manner so as to sealingly engage the mouth interface around the user's mouth and the pillows with the user's nose when a sealing force applied by the headgear strap assembly. | 2016-06-09 |
| 20160158476 | ASYMMETRICAL NASAL DELIVERY ELEMENTS AND FITTINGS FOR NASAL INTERFACES - A nasal interface uses asymmetrical nasal delivery elements to deliver an asymmetrical flow through the interface to both nares or to either nare, and a mouthpiece may be inserted to maintain a leak, to improve dead space clearance in the upper airways, decrease peak expiratory pressure, reduce noise, increase safety of the therapy for smaller patients and reduce resistance in the interface allowing desired flow rates to be achieved at reduced motor speeds of associated flow generating devices. Different forms of fittings, such as sleeves or inserts can be attached to nasal delivery elements to improve or optimise the therapeutic effects of nasal high flow. It may allow high pressures to be achieved at lower flow rates, reduce noise, improve patient comfort and efficiently clear anatomical dead space. | 2016-06-09 |
| 20160158477 | MODULAR PULMONARY TREATMENT SYSTEM - A modular pulmonary treatment system is provided and includes a patient interface device defined by a body which defines a hollow interior. The system also includes a first inhalation valve associated with the body and located along an inhalation flow path for providing selective fluid communication with the hollow interior of the body; and at least one exhalation valve assembly detachable coupled to the body for discharging exhaled gas from the hollow interior to atmosphere. The at least one exhalation valve assembly comprises: (a) an exhalation valve cartridge including a housing having a perforated bottom wall with a post extending outwardly therefrom; (b) a valve member configured to seat against the perforated bottom wall and including an opening through which the post extends; and (c) a valve retainer for placement over the post, whereby the valve member is securely held in place against the perforated bottom wall. | 2016-06-09 |
| 20160158478 | MODULARIZED RESPIRATORY TREATMENT APPARATUS - A modularized respiratory treatment apparatus provides various respiratory pressure treatments. The apparatus may be formed by discrete connectable modules such as a flow generator module, alarm module and/or humidifier module. Each module may include its own external casing or housing to independently retain or enclose the respective components that serve the function of the module. Different modules may be adapted with different components and functionalities and may be readily coupled using standardized gas and electrical connection configurations that have flow and communication paths that extend through the modules. When coupled, operation of the respiratory treatment apparatus may be controlled by detection of different modules, such as the alarm module that generates visual and/or audible alarms based on detected conditions, so as to selectively enable or disable different respiratory treatments. The discrete modules of the medical treatment apparatus may include tamper resistant locking mechanisms to impede unauthorized separation of some modules. | 2016-06-09 |
| 20160158479 | APPARATUS FOR FLUID TUBE - A fluid tube is disclosed herein. The breathing circuit tube has a wall which comprises a hollow geometry. The wall defines a passageway with a central longitudinal axis therethrough. The wall is expandable and contractible to adjust a diameter and a length of the passageway. The wall includes one or more corrugations that expand and contract to adjust the diameter and length of the passageway. The corrugations extend between terminal end portions of the wall. | 2016-06-09 |
| 20160158480 | TUBE FOR BREATH-INDUCING AND APPARATUS FOR BREATH-INDUCING USING THE SAME - A breath-inducing tube to assist a patient's breathing and a breath-inducing apparatus using the same are disclosed. The breath-inducing tube can include: a divider having a connection port, an intake port and an exhaust port; a connection tube which is connected to the connection port such that the connection tube is connected to a patient; an exhaust tube which is connected to the exhaust port to discharge a patient's breathing gas; an inhalation part including a first inhalation tube of which one end is connected to the intake port and a second inhalation tube; and a heating module which has one end connected to the other end of the first inhalation tube and another end connected to the second inhalation tube to apply heat to the breathing gas introduced through the second inhalation tube and the first inhalation tube. | 2016-06-09 |
| 20160158481 | CONTROLLING ARTERIAL BLOOD GAS CONCENTRATION - A system for controlling an amount of at least one gas X in a subject's lung to target at least one end tidal partial pressure of at least one gas X (PetX | 2016-06-09 |
| 20160158482 | APPARATUS FOR HUMIDIFYING A RESPIRATORY GAS - The invention concerns an apparatus for supplying a respiratory gas, a humidifying apparatus, a respiratory gas tube and a connecting apparatus therefor. The apparatus of the invention includes a blowing device for delivering the respiratory gas, a housing device which has a bottom region, a top surface region and a side region extending upwardly between the top surface region and the cover region, as well as a connecting device for connecting a humidifying apparatus for humidifying the respiratory gas, wherein the connecting device is arranged in the side region of the apparatus in such a way that the humidifying apparatus can be laterally coupled thereto. The humidifying apparatus according to the invention is distinguished by a partial amount discharge device for passing a partial amount of the liquid pre-stored in a liquid storage space into a humidifying region. The respiration tube according to the invention includes a connecting plug structure which has both a respiratory gas connecting portion and also a pressure measuring tube connecting portion. | 2016-06-09 |
| 20160158483 | Methods and Apparatus for Administering Local Anesthetic - Apparatus for administering certain nerve blocks includes a sheath constructed from a flexible ultrasound echogenic material, a more rigid introducer/dilator for introducing the sheath into the patient, and an ultrasound echogenic catheter for inserting through the sheath once the distal end of the sheath is in place adjacent the nerve(s) to be blocked and the introducer/dilator has been withdrawn. The catheter has provisions at its proximal end for connecting to a source of local anesthetic. Methods for use of this apparatus are also described. | 2016-06-09 |
| 20160158484 | Surgical Instrument having an Integrated Local Anesthetic Delivery System - A surgical instrument includes a handle portion having a distal end, a proximal end, and a substantially hollow body defining a valve chamber therein; a curved incising tube partially housed within the handle portion adjacent the handle portion proximal end, extending a predetermined distance from the handle portion, and in fluid communication with the valve chamber; a local anesthetic inlet tube partially housed within the handle portion adjacent the handle portion distal end, extending a predetermined distance from the handle portion, and in fluid communication with the valve chamber; a local anesthetic delivery actuator disposed on the handle portion, whereby the local anesthetic delivery actuator is selectively operative between opened and closed valve chamber positions. | 2016-06-09 |
| 20160158485 | HEAD MOUNTED LIGHT THERAPY DEVICE - A portable, lightweight, head-mounted light therapy device is disclosed. The device comprises an one or more selectable light sources, such as light emitting diodes (LEDs), to provide bright or dim red light, bright or dim white light, or a combination thereof, selectable by the user, for shining on the user's face and eyes. The device can be used for the treatment of light deficiency disorders or conditions and circadian rhythm disorders and disturbances. | 2016-06-09 |
| 20160158486 | SYSTEM AND METHOD FOR PROVIDING LIGHT THERAPY AND MODIFYING CIRCADIAN RHYTHM - Systems and methods to provide light therapy to a subject use one or more light sources configured to emit electromagnetic radiation in multiple stages using multiple wavelengths. By virtue of the emitted electromagnetic radiation impinging on the subject, the phase of the circadian rhythm of the subject is modified. | 2016-06-09 |
| 20160158487 | SYSTEM AND METHOD FOR PROVIDING LIGHT THERAPY AND MODIFYING CIRCADIAN RHYTHM - Systems and methods to provide light therapy to a subject use a light source configured to emit pulses of electromagnetic radiation consisting substantially of blue light. By virtue of the emitted pulses of electromagnetic radiation within a particular range of wavelengths impinging on an eye or eyelid of the subject, the phase of the circadian rhythm of the subject is shifted. Such a shift may be accomplished in such a way that the level of melatonin production is not substantially suppressed. | 2016-06-09 |
| 20160158488 | Mechanical Device for Soothing Agitated Patients - A system for soothing an agitated patient, including a motor, a linkage operationally connected to the motor, an armature operationally connected to the linkage, and a lifelike hand connected to the armature. Energization of the motor enables the lifelike hand to move in a generally circular, rubbing motion. | 2016-06-09 |
| 20160158489 | SELF-EXPANDING CANNULA - Disclosed is a self-expanding cannula, systems using such cannulae, and methods of their use. The cannulae may comprise single lumen cannula (SLC) configurations and double lumen cannula (DLC) configurations, and include at least a first cannula and a self-expanding wire frame attached to the first cannula. Self-expanding wire frame is automatically expandable from a compressed state (providing a reduced cannula diameter as it is moved through a patients body to the site at which it is to be deployed) to an expanded state (which increases the diameter of the cannula to the diameter intended for its normal use). The expanded wire frame provides radial support to prevent a drainage canal (whether a patients blood vessel or a portion of the system inserted into the patients blood vessel) from collapsing as fluid is drained from the patient. | 2016-06-09 |
| 20160158490 | CATHETER DEVICES AND METHODS FOR MAKING THEM - Tubular devices are provided that include a proximal end, a distal end sized for introduction into a patient's body, a central lumen, a conductor extending between the proximal and distal ends adjacent the central lumen, reinforcement members including windings extending helically around the central lumen, and an outer jacket. The tubular device includes a first portion in which the conductor extends helically around the central lumen, and a second portion in which the conductor extends longitudinally and either a) all of the windings surround the central lumen and the conductor remains outside the windings, b) at least some of the windings pass between the central lumen and the conductor and at least some of the windings surround both the central lumen and the conductor, and c) all of the windings surround both the central lumen and the conductor. Methods for making such tubular devices are also provided. | 2016-06-09 |
| 20160158491 | Multiple Wall Dimensionally Recoverable Tubing for Forming Reinforced Medical Devices - A multi-layered dimensionally recoverable tubing system and method for making the same, in which the system has a first layer, a second layer, and a reinforcing structure. The first layer includes at least one crosslinkable polymer. The second layer is disposed adjacent to the first layer and includes a polymer. A reinforcing structure is disposed adjacent to the first layer. One or both of the first layer and second layer are dimensionally recoverable. The first layer is substantially crosslinked, and the second layer is substantially uncrosslinked. To form a reinforced medical device, the system is heated and dimensionally recovered, where the reinforcing structure becomes incorporated in the second layer. | 2016-06-09 |
| 20160158492 | PARTIALLY SHRINKABLE TUBING WITH MULTIPLE LUMENS AND ASSOCIATED METHODS - A partially shrinkable tube includes a plurality of lumens. At least one lumen of the plurality of lumens may be shrinkable from an expanded state to an unexpanded state. At least another lumen of the plurality of lumens may remain in an unexpanded state. Methods for manufacturing and using such tubing are also disclosed. | 2016-06-09 |
| 20160158493 | Indicia Informative of Characteristics of Insertable Medical Devices - A system by which resource information relating to an insertable medical device, such as an intravascular catheter, can be identified by its source so as to be accessed by a practitioner, caregiver, or patient, is disclosed. In particular, a resource information key is included at a predetermined key location on or proximate to the medical device, wherein the key indicates the source of the resource information. In one example embodiment, therefore, an insertable medical device for establishing intravascular access to a patient, such as a peripherally inserted central catheter (“PICC”), is disclosed and comprises: an internal portion, and a portion external to the patient that includes a resource information key indicating a website where a user can acquire resource information relating to the medical device. In other embodiments indicia are provided as quick response (“QR”) codes, and as various markings to indicate compatibility of the medical device with ethanol. | 2016-06-09 |
| 20160158494 | ROBOTIC CATHETER SYSTEM - A catheter system including a housing and a drive mechanism supported by the housing is provided. The drive mechanism includes an engagement structure configured to engage and to impart movement to a guide wire. The engagement structure defines a path for the guide wire, and the engagement structure is moveable between an engaged position in which the engagement structure engages the guide wire and a disengaged position in which the engagement structure does not engage the guide wire. The catheter system includes a biasing element configured to bias the engagement structure toward the engaged position, and the biasing element is aligned generally parallel to the path defined by the engagement structure. | 2016-06-09 |
| 20160158495 | CATHETER AND MANUFACTURING METHOD THEREOF - A catheter is provided, which includes a tube including a first portion, a second portion connected to the first portion and having a less rigidity than the first portion, and a plurality of holes longitudinally penetrating the first portion and the second portion and being isolated from one another, a wire passing through two of the plurality of holes of the tube, and a cap being engaged with an extrusion portion of the wire extruded from the two holes of the tube in a manner of enclosing the extrusion of the wire, being connected to one end of the tube, and having a greater rigidity than the first portion and the second portion of the tube. | 2016-06-09 |
| 20160158496 | STEERING CONTROL MECHANISM FOR CATHETERS - A steering handle for a catheter. The steering handle includes a thumb knob arrangement for driving a cam assembly that in turn actuates a pull wire or pull wires. In some embodiments, the cam assembly includes a set of dual pins that actuate the pull wire in a quasi-linear relationship between cam rotation and axial displacement of the wire. In certain embodiments, the second set of dual pins imparts a reverse action on a second pull wire, also in quasi-linear fashion. That is, when one wire is released by the cam assembly, the other wire is taken in by the cam assembly. In various embodiments, the quasi-linear action can cause release of more pull wire than is taken in, thereby helping prevent the released pull wire to act as an unwanted counter force to the actuated pull wire. | 2016-06-09 |
| 20160158497 | STEERABLE CATHETER WITH PULL WIRE - In one representative embodiment, a steerable catheter device comprises a shaft comprising a proximal portion, a distal portion, and a pull-wire lumen that extends at least partially through the proximal and distal portions. A pull wire extends through the pull-wire lumen and has a proximal end portion and a distal end portion, wherein the distal end portion of pull wire is fixed to the distal end portion of the shaft. An adjustment mechanism is operatively connected to the proximal end portion of the pull wire and configured to increase and decrease tension in the pull wire to adjust the curvature of the distal portion of the shaft. An axially non-compressible pull-wire sleeve extends co-axially through the pull-wire lumen and over the pull wire. | 2016-06-09 |
| 20160158498 | Integrated Vascular Delivery System - An integrated vascular delivery system having a frame configured to receive a catheter insertable in a patient to deliver fluid at an insertion site. The frame includes a first hub, a second hub, and a pair of flexible lateral members extending between the hubs and including a tubular lateral member. The system also includes a fluidic channel that fluidically communicates with the catheter, wherein the fluidic channel passes through the tubular lateral member and at least one of the hubs, and includes a fixed turnabout portion in which fluid flows in a direction different from that within the catheter. The first and second hubs provide anchoring points on the patient distributed around the insertion site and on opposite ends of the catheter, thereby anchoring the frame to the patient and stabilizing the catheter. A method is provided for using an integrated vascular delivery system. | 2016-06-09 |
| 20160158499 | Two-Part Multi-Function Vascular Catheter And Integrated Circumferentially Sealing Securement Dressing - A catheter and dressing assembly is disclosed including a dressing having a distal adhesive plate configured for attachment to a skin region surrounding a catheter insertion site to provide a first circumferential seal around the catheter at the insertion site, a dressing body extending from the adhesive plate and configured to surround a catheter segment external to the insertion site and a proximal sealing element. The assembly further includes a two-part catheter having a first distal part consisting of a hub base bonded to a tubular catheter body; and a second proximal interconnector-cap that is adapted to couple to the distal hub base, whereby the attachment of the interconnector-cap to the hub-tubular body portion of the catheter establishes at least one continuous fluid pathway extending from a proximal end of the interconnector-cap to a lumen of the catheter and wherein either the hub base or the interconnector cap further comprises a mating feature for mating to the proximal sealing element of the dressing such that the dressing and interconnector-cap provide a second circumferential seal around the catheter body. | 2016-06-09 |
| 20160158500 | ANCHOR DEVICE FOR USE WITH CATHETERS - An anchor device to simplify catheterization procedures, particularly for insertion and maneuvering of large catheters in tortuous arteries, vessels, or other lumen is disclosed. In some embodiments, the anchor device includes an anchor stent formed from a plurality of zig-zag shaped wire elements that are coupled together. The device further includes a plurality of connector struts attached at a proximal end of the anchor stent, the connector struts coalescing to form a strut tip. A guide device, such as a guidewire, is attached to the anchor stent at the strut tip and may be used to guide the anchor stent into the arteries or other vessels and toward a target treatment site. | 2016-06-09 |
| 20160158501 | PERCUTANEOUS SCALPEL AND TISSUE DILATOR - Embodiments herein provide a combined percutaneous scalpel and tissue dilator. Embodiments herein also improve (a) the process, and (b) the result of placement of percutaneous vascular access catheters and other similar devices by providing a combined scalpel-dilator that cuts with minimal tissue disruption the percutaneous access tract necessary for a catheter or other device. | 2016-06-09 |
| 20160158502 | Methods and Devices for Transcarotid Access - Disclosed is an arterial access sheath for introducing an interventional device into an artery. The arterial access sheath includes an elongated body sized and shaped to be transcervically introduced into a common carotid artery at an access location in the neck and an internal lumen in the elongated body having a proximal opening in a proximal region of the elongated body and a distal opening in a distal region of the elongated body. The internal lumen provides a passageway for introducing an interventional device into the common carotid artery when the elongated body is positioned in the common carotid artery. The elongated body has a proximal section and a distalmost section that is more flexible than the proximal section. A ratio of an entire length of the distalmost section to an overall length of the sheath body is one tenth to one half the overall length of the sheath body. | 2016-06-09 |
| 20160158503 | CATHETER ASSEMBLY - A catheter assembly including a catheter hub being connectable to a device for the infusion or withdrawal of fluids; a hollow extension tube connected at its distal end to the catheter hub, the extension tube connectable at its proximal end to a device for infusing fluid into the chamber within the catheter hub; a valve assembly disposed within the chamber of the catheter hub having a first valve member and a second valve member preventing the flow of fluid through the chamber to or from the proximal end of the catheter hub. A needle guard assembly is also provided. | 2016-06-09 |
| 20160158504 | Butterfly needle with a protective device - A butterfly needle with a protective device: includes a central body having a proximal end and an opposite distal end; a pair of wings bilaterally extending from the central body; a safety device designed to be automatically actuated by traction; and a needle with a shank having an engaging element near its tip for engagement with the safety device and supported by a needle hub at an opposite proximal end, the needle being slidingly longitudinally received in the central body, which includes an inner housing chamber between the proximal end and the distal end, wherein the safety device is irreversibly slidingly housed between a rest position and an actuated position. | 2016-06-09 |
| 20160158505 | APPLICATOR FOR ANTISEPTIC OR MEDICATIONS - Disclosed herein is an applicator that can be advanced over an in-situ guidewire and into the subcutaneous tissue or tract prior to CVC placement or replacement, allowing sterilization of the subcutaneous tissue or tract before CVC introduction. The unique shape of the applicator allows sterilization of the skin surface as well as the subcutaneous tissue or tract of the original CVC that lies beneath the skin, which are difficult to reach and effectively sterilize with other applicators. | 2016-06-09 |
| 20160158506 | PERIPHERAL ANTEGRADE PERFUSION AND OCCLUSION DEVICE - This disclosure relates generally to systems and methods for occluding vessels of the heart and inducing cardioplegic arrest to facilitate the performance of cardiac procedures. An aortic occlusion and perfusion device includes an expandable member configured to expand within the aorta to secure the device within the aorta, and a catheter extending proximally from the expandable member and in fluid communication with the expandable member. The catheter can define a plurality of openings along its length through which blood can pass with one or more of the openings located proximal to the expandable member and one or more of the openings located within the expandable member. The device can also include a flow control sheath disposed around the catheter member such that axial movement of the flow control sheath relative to the catheter selectively occludes or uncovers one or more of the openings located proximal to the expandable member. | 2016-06-09 |
| 20160158507 | Medical Device for Dispersing Medicaments - For selective treatment of diseased tissue sections or organ parts, the surface of medical devices entering into contact with areas thereof under pressure is coated with lipophilic substantially water-insoluble medicaments binding to various tissue components with good adherence thereto, said medicaments having an effect thereupon a short time after entering into contact therewith without exerting a harmful influence upon adjacent healthy tissue. | 2016-06-09 |
| 20160158508 | INTEGRAL DILATION ELEMENT FOR A BALLOON CATHETER - A balloon catheter is provided for dilating hardened stenoses. The balloon catheter has dilation elements integrally formed on the outer surface of the balloon. The dilation elements have cross-sectional shapes that improve the performance of the balloon catheter. | 2016-06-09 |
| 20160158509 | ACTIVELY TRACKED MEDICAL DEVICES - An actively tracked medical device comprising: a dilator having an inner tubular main body having a distal end and a proximal end, said tubular main body including at least first and second receiving channels positioned in a spaced apart relationship on an outer surface of said tubular main body; a region at the distal end of said tubular main body for supporting one or more tracking coils; an atrumatic tip portion operably coupled and positioned distal to said main body; a lumen extending through said tubular main body, said tip support and said atraumatic tip portion; and an outer polymer body having first and second ends, said outer polymer body operably covering said inner tubular main body and said tracking coils, said first end terminating adjacent a proximal end of said atraumatic tip portion and said second end terminating adjacent said hub. | 2016-06-09 |
| 20160158510 | CUTANEOUS TREATMENT APPARATUS AND METHODS OF USE - Cutaneous treatment apparatuses are provided that enhance percutaneous absorption of a treatment formulation. Related methods are also provided. In general, examples of the cutaneous treatment systems and/or apparatuses described herein are capable of attaching to a cutaneous surface and applying a treatment formulation to a localized cutaneous region. Embodiments of a cutaneous treatment apparatus generally include a heater and a treatment delivery component, including a treatment portion. The treatment portion includes a treatment formulation, including a therapeutic compound, and a treatment surface configured to contact the cutaneous region. The heater component is removably couplable with the treatment delivery component and is configured to transfer heat to the treatment portion. Upon heating, the therapeutic compound is configured to release from the treatment portion through the treatment surface towards the cutaneous region. | 2016-06-09 |
| 20160158511 | FABRICATION PROCESS OF PHASE-TRANSITION MICRONEEDLE PATCH - The application discloses a method to fabricate microneedle patches, comprising a) casting (painting and pasting) an aqueous polymer solution on a mold of array of micro-holes which is made of porous materials; b) sucking the polymer solution into the micro-holes by applying vacuum at the back of the mold; d) freezing and thawing the casted polymer solution to induce gelation; and e) drying the gelled polymer solution. Specifically, the present invention describes a process and composition of polymeric microneedlepatch which overcomes the limitations of existing microneedles systems and may be used for transdermal delivery system for therapeutics and other applications. | 2016-06-09 |
| 20160158512 | MICRONEEDLE ARRAY AND MICRONEEDLE ARRAY MANUFACTURING METHOD - The purpose of the present invention is to provide: a microneedle array that does not readily break during puncture and thereby improves the reliability of puncturing, the microneedle array being capable of administering the desired amount of the target substance; and a microneedle manufacturing method for manufacturing a microneedle array of such description. To achieve the above purpose, the invention is characterized in being provided with: a substrate; a plurality of microneedle base sections formed integrally in a protruding manner on the substrate; and microneedle end sections installed at the ends of the microneedle base sections to form microneedles and provided with in vivo solubility or biodegradability, the microneedle end sections holding the target substance, a recess for admitting the microneedle end sections being provided to the microneedle base sections, and a part of the microneedle end sections being admitted into the recess for admitting the microneedle end sections. | 2016-06-09 |
| 20160158513 | BALLOON CATHETER HAVING MICRO NEEDLES AND MANUFACTURING METHOD FOR THE SAME - A balloon catheter which is inflated after insertion into a tubular tissue includes: a balloon catheter body made of a polymer material, which is inflatable by fluid injection, and a plurality of microneedles formed on the surface of the balloon catheter body, wherein the microneedles are formed by transferring a biocompatible polymer resin or photocurable resin, filled in intaglio patterns formed on a mold, which have a shape corresponding to a shape of the microneedles, to the surface of the balloon catheter body which is in close contact with the mold, by a thermal molding, thermal crosslinking or photocuring process. | 2016-06-09 |
| 20160158514 | METALLIC MICRONEEDLES - Methods for fabricating metallic microneedles are disclosed. One method comprises providing a mold pillar; forming an apertured electrically-conductive layer over the mold pillar; and depositing a metal layer over the electrically-conductive layer to provide an apertured microneedle. Another method comprises providing a mold pillar; depositing a first metal layer over the mold pillar to provide a first microneedle; removing the first microneedle from the mold pillar; and depositing a second metal layer over the mold pillar to provide a second microneedle. | 2016-06-09 |
| 20160158515 | TRANSDERMAL THERAPEUTIC SYSTEM WITH PRESSURE GENERATING DEVICE - A transdermal therapeutic system with a system support, at least one advancing element which is embedded into the system support, and at least one active ingredient reservoir which can be elastically deformed at least in some regions and which is embedded into the advancing element. On the application side of the transdermal therapeutic system, the system support surrounds the advancing element, and the advancing element surrounds the active ingredient reservoir. The advancing element comprises a swelling body which can be expanded by means of a liquid intake. The system support is designed to be rigid at least in some regions. A transdermal therapeutic system is developed which enhances the effect of the advancing element | 2016-06-09 |
| 20160158516 | THERAPEUTIC AGENT PREPARATIONS FOR DELIVERY INTO A LUMEN OF THE INTESTINAL TRACT USING A SWALLOWABLE DRUG DELIVERY DEVICE - Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many embodiments provide a swallowable device for delivering the agents. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade to release the drug into the bloodstream to produce a therapeutic effect. The preparation can be operably coupled to delivery means having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract. | 2016-06-09 |
| 20160158517 | MEDICAL DEVICE FOR DETECTION OF A LEAKAGE OF FLUID ON A SUBJECT - A medical device for detecting a leakage of fluid on a subject includes a support, configured for being secured on the subject, and an optical sensor on the support. The support defines, in a region between the optical sensor and a lower face thereof, a detection surface that can be reached by leakage fluid. The optical sensor is arranged for detecting a leakage of fluid. The optical sensor has a sensor body with an emitter and a receiver of electromagnetic radiation. The support and the sensor body have mutual-coupling means, for retaining the sensor body on the support in such a way that a presence of leakage fluid can be detected via the optical sensor. | 2016-06-09 |
