| 23rd week of 2011 patent applcation highlights part 54 |
| Patent application number | Title | Published |
|---|
| 20110136998 | Catalyst Composition with Mixed Selectivity Control Agent and Method - The present disclosure provides a Ziegler-Natta catalyst composition comprising a procatalyst, a cocatalyst and a mixed external electron donor comprising a first selectivity control agent, a second selectivity control agent, and an activity limiting agent. A polymerization process incorporating the present catalyst composition produces a high-stiffness propylene-based polymer with a melt flow rate greater than about 50 g/10 min. The polymerization process occurs in a single reactor, utilizing standard hydrogen concentration with no visbreaking. | 2011-06-09 |
| 20110136999 | PROCESS FOR PREPARATION OF FLUOROSILICON POLYMER - Fluorosilicon polymers are disclosed that are prepared by a process comprising reacting a) iodinated oligomers having copolymerized units of perfluoro(methyl vinyl ether) and vinylidene fluoride or tetrafluoroethylene that contain 40-90 mole percent copolymerized units of vinylidene fluoride or tetrafluoroethylene and 10-60 mole percent copolymerized units of perfluoro(methyl vinyl ether), said oligomers having two functional endgroups and having a number average molecular weight between 1000 and 25,000 with b) a methoxyvinyl silane or an ethoxyvinyl silane to form a silicon-containing polymeric adduct that is further reacted with an acid to form a crosslinked fluorinated polymer. | 2011-06-09 |
| 20110137000 | METHOD FOR PREPARING POLYMER MATERIALS DOPED WITH METAL ELEMENTS AND RESULTING MATERIALS - The invention relates to a process for preparing a polymeric material doped with metal elements, comprising a step of polymerization of at least one monomer comprising at least one ethylenic function, said monomer being complexed with a metal element. | 2011-06-09 |
| 20110137001 | COPOLYMER FOR IMPROVED DRYING - The invention relates to a novel copolymer containing vinyl-pyrrolidone units. The copolymer further includes units of the betaine type. The invention further relates to the use of the copolymer in compositions for drying dishes, said polymer particularly improving the drying thereof. | 2011-06-09 |
| 20110137002 | METHOD FOR THE ENZYME-CATALYSED HYDROLYSIS OF POLYACRYLIC ACID ESTERS, AND ESTERASES USED THEREFOR - The invention relates to a method for the enzyme-catalysed hydrolysis of polyacrylic acid esters. According to said method, at least one polyacrylic acid ester is provided and incubated with at least one enzyme selected from enzymes (EC 3.1) acting on ester bindings, until the ester groups contained in the polyacrylic acid ester are partially or fully hydrolytically split, and optionally the modified polymer obtained thereby is isolated. The invention also relates to the enzymes used and mutants thereof, nucleic acids coding for the enzymes, vectors comprising the nucleic acids, micro-organisms comprising the vectors, and the use of the enzymes, the vectors or the micro-organisms for carrying out a method for the enzyme-catalysed hydrolysis of polyacrylic acid esters. The present application also relates to polymer reaction products that can be obtained by the method, and methods for producing esterases. | 2011-06-09 |
| 20110137003 | Classified Catalyst Composition, Apparatus, and Method - The present disclosure is directed to an apparatus and process for producing a catalyst composition and a low-fines catalyst composition in particular. A crossflow classification device is used to separate large catalyst particles from catalyst fines, A slurry of a catalyst composition is introduced into the crossflow classification device. A classified catalyst composition is retrieved from a retentate produced as a result of subjecting the catalyst slurry to a crossflow classification process. The solids content of the pre-classified and/or post-classified catalyst slurry is determined by way of NMR spectroscopy. The solids content determination accounts for migration of wash liquid from the catalyst composition and into the slurry liquid phase, The classified catalyst composition has a low-fines content and produces a polyolefin composition with a low polymer fines content. | 2011-06-09 |
| 20110137004 | Grafting Polymerization of Guar and Other Polysaccharides by Electron Beams - A method of grafting galactomannan-type polysaccharide polymers, preferably guar, to a functional group by irradiation with high energy electron beams in the presence of an unsaturated monomer-compressing the described functional group. The method may include the depolymerization of the grafted polymer to a pre-selected low molecular weight. The preferred galactomannans for treatment according to this method are guar gum, guar splits and hydroxypropyl guar. In a preferred embodiment the guar gum is also depolymerized, preferably to a molecular weight of below about 700,00 Daltons, and most preferably to a molecular weight of between about 100,00 Daltons to about 250,00 Daltons. The depolymerized guar most preferably has a polydispersity of less than about 3.0 and is useful in oil well fracturing to enhance oil production. | 2011-06-09 |
| 20110137005 | Chain Extenders - This invention provides chain extender compositions. These compositions comprise | 2011-06-09 |
| 20110137006 | Methods for Polymerizing Films In-Situ - A method for formation of a polymer film in-situ according to the invention comprises steps of: providing a polymerizable composition in one or multiple parts; initiating polymerization of the polymerizable composition to form a polymerizing composition; prior to completion of polymerization of the polymerizable composition, forming a film therefrom; and fully polymerizing the polymerizing composition to form the polymer film. | 2011-06-09 |
| 20110137007 | METHOD FOR PRODUCING AN AMINOHYDROXYBENZOIC ACID-TYPE COMPOUND - Provided is a method for efficiently producing a 3-amino-4-hydroxybenzoic acid-type compound by culturing a coryneform bacterium that has a gene encoding a mutated aspartokinase not subject to feedback inhibition, and that is transformed with a recombinant vector containing a DNA encoding a protein having an activity to form 3-amino-4-hydroxybenzoic acid from dihydroxyacetone phosphate and aspartate semialdehyde. | 2011-06-09 |
| 20110137008 | HIGH STRENGTH POLYIMIDE MEMBRANE AND METHOD FOR FORMING THE SAME - The present invention discloses a polyimide membrane synthesized by one or more emeraldine amine-capped aniline trimer oligomer, one or more dianhydride, and an optional diamine, whereby the weight-average molecular weight of the polyimide membrane ranges from 50,000 to 200,000, and the Yung's Modulus of the polyimide membrane is equal to or more than 3 GPa. | 2011-06-09 |
| 20110137009 | POLYAMIC ACID, POLYIMIDE, MANUFACTURING METHOD THEREOF, AND POLYIMIDE FILM - A polyamic acid that is a condensation reaction product of one or more acid anhydrides and one or more carbonate-based diamine compounds, along with a polyimide obtained by imidizing the polyamic acid, a method of manufacturing the same, and a polyimide film made therefrom. | 2011-06-09 |
| 20110137010 | PHOSPHORAMIDITES FOR SYNTHETIC RNA IN THE REVERSE DIRECTION, EFFICIENT RNA SYNTHESIS AND CONVENIENT INTRODUCTION OF 3'-END LIGANDS, CHROMOPHORES AND MODIFICATIONS OF SYNTHETIC RNA - The present invention provides building blocks and methods for synthesizing very pure RNA in a form that can efficiently be modified at the 3′ end. Reverse RNA monomer phosphoramidites have been developed for RNA synthesis in 5′→3′ direction, leading to very clean oligo synthesis that allows for the introduction of various modifications at the 3′-end cleanly and efficiently. Higher coupling efficiency per step have been observed during automated oligo synthesis with the reverse RNA amidites disclosed herein, resulting in a greater ability to achieve higher purity and produce very long oligonucleotides. The use of the reverse RNA phosphoramidites in the synthetic process of this invention leads to oligonucleotides free of N+1 species. | 2011-06-09 |
| 20110137011 | HYPERGLYCOSYLATED HUMAN COAGULATION FACTOR IX - The invention relates to hyperglycosylated human coagulation factor IX polypeptides, to processes for preparing said polypeptides, to pharmaceutical compositions comprising said polypeptides and to the use of the compounds for the treatment of diseases alleviated by human coagulation factor IX, in particular, but not exclusively hemophilia. | 2011-06-09 |
| 20110137012 | CELL CULTURE METHOD USING AMINO ACID-ENRICHED MEDIUM - Methods of culturing cells capable of producing desired proteins to obtain the proteins by use of a medium from which biological components are excluded as much as possible are provided. Specifically, a culture method characterized by culturing while maintaining a specific amino acid in a culture solution at a high concentration, and a cell culture fed-batch medium for use in the method are provided. | 2011-06-09 |
| 20110137013 | NOVEL COLLAGEN-LIKE PROTEIN CLAC, PRECURSOR THEREOF AND GENES ENCODING THE SAME - A novel human collagen-like protein CLAC occurring in brain amyloid and its precursor CLAC-P; genes encoding the same; cDNA of mouse CLAC-P and its deduced amino acid sequence; antibodies specific to these proteins; and methods of diagnosing treating and preventing Alzheimer's disease by using the same. | 2011-06-09 |
| 20110137014 | SUPER HUMANIZED ANTIBODIES - Disclosed herein are methods for humanizing antibodies based on selecting variable region framework sequences from human antibody genes by comparing canonical CDR structure types for CDR sequences of the variable region of a non-human antibody to canonical CDR structure types for corresponding CDRs from a library of human antibody sequences, preferably germline antibody gene segments. Human antibody variable regions having similar canonical CDR structure types to the non-human CDRs form a subset of member human antibody sequences from which to select human framework sequences. The subset members may be further ranked by amino acid similarity between the human and the non-human CDR sequences. Top ranking human sequences are selected to provide the framework sequences for constructing a chimeric antibody that functionally replaces human CDR sequences with the non-human CDR counterparts using the selected subset member human frameworks, thereby providing a humanized antibody of high affinity and low immunogenicity without need for comparing framework sequences between the non-human and human antibodies. Chimeric antibodies made according to the method are also disclosed. | 2011-06-09 |
| 20110137015 | Markers of XMRV Infection and Uses Thereof - The present invention relates generally to assays for the detection of Xenotropic Murine Leukemia Virus-related Retrovirus (“XMRV”) and diseases associated with XMRV infection. Additionally, the invention relates to specific XMRV antigens capable of inducing an immunogenic response as well as XMRV-related nucleic acids having significant diagnostic, screening, and therapeutic utilities. | 2011-06-09 |
| 20110137016 | COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF TUMOR - The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same. | 2011-06-09 |
| 20110137017 | CYSTEINE ENGINEERED ANTIBODIES AND CONJUGATES - Antibodies are engineered by replacing one or more amino acids of a parent antibody with non cross-linked, highly reactive cysteine amino acids. Antibody fragments may also be engineered with one or more cysteine amino acids to form cysteine engineered antibody fragments (ThioFab). Methods of design, preparation, screening, and selection of the cysteine engineered antibodies are provided. Cysteine engineered antibodies (Ab), optionally with an albumin-binding peptide (ABP) sequence, are conjugated with one or more drug moieties (D) through a linker (L) to form cysteine engineered antibody-drug conjugates having Formula I: | 2011-06-09 |
| 20110137018 | MAGNETIC SEPARATION SYSTEM WITH PRE AND POST PROCESSING MODULES - A system for sorting and trapping magnetic target species includes a microfluidic chamber designed to receive and then temporarily hold magnetic particles in place within the module. A pre-processing module may mix a sample and magnetic particles to cause certain species in the sample to be labeled. The micorfluidic chamber may include a mechanism to move magnetic particles within the chamber. A post-processing module or the microfluidic chamber may be used to separate the labeled species from the magnetic particles by adding a release reagent. The magnetic particles and/or their payloads may be released and separately collected at an outlet of the chamber or the post-processing module. | 2011-06-09 |
| 20110137019 | NUCLEIC ACID COMPRISING ZWITTERIONIC NUCLEOTIDES - This invention provides pH-responsive zwitterionic nucleotides and nucleic acids comprising said nucleotides, wherein said zwitterions are constituted from one or more anionic internucleoside linkages and one or more cationic moieties and said zwitterionic nucleotides further comprise either one or more hydrophobic moieties or one or more TEE's with the general structure (I) Hydrophobic element-pH-responsive hydrophilic elements (I). | 2011-06-09 |
| 20110137020 | Method and Device for Purifying Nucleic Acids - The invention concerns a method for isolating and purifying nucleic acids from a sample and a device that is suitable therefore. | 2011-06-09 |
| 20110137021 | SULFUR TRANSFER REAGENTS FOR OLIGONUCLEOTIDE SYNTHESIS - The use of N-formamidino-5-amino-3H-1,2,4-dithiazole-3-thiones, 5-phenyl-3H-1,2,4-dithiazole-3-thiones, and derivatives thereof as novel, efficient sulfur-transfer reagents is disclosed. Sulfur transfer from these reagents to compounds containing a P(III) atom (e.g., triphenylphosphine, 5′-O-DMT-thymidine 2-cyanoethyl-(N,N-diisopropyl)phosphoramidite, and 5′-O-DMT-3′-O-levulinyl dithymidilyl 2-cyanoethyl phosphite), was studied in solution by | 2011-06-09 |
| 20110137022 | METHOD FOR THE ANALYSIS OF OLIGONUCLEOTIDES - A method for the analysis of oligonucleotides is provided. The method comprises: desalting a mixture of oligonucleotides under conditions such that there is substantially no separation of the mixture of oligonucleotides, and/or by on-line desalting, introducing the desalted mixture of oligonucleotides into a mass spectrometer; and quantifying one or more oligonucleotides comprised in the mixture by mass spectrometry. | 2011-06-09 |
| 20110137023 | METHOD FOR PRODUCING PHOSPHATE-BRIDGED NUCLEOSIDE CONJUGATES - The invention relates to a method for producing phosphate-bridged nucleoside conjugates. In the method a nucleophile is first dissolved in a non-aqueous solvent and dried, and a cyclosaligenyl phosphate compound is subsequently added to the solution. | 2011-06-09 |
| 20110137024 | METHOD FOR PRODUCING ISOINDOLE - Disclosed is a method for manufacturing isoindolic compound, which can adopt a condition capable of being put to industrially practical use, which can produce stable isoindolic compound, and which can further produce the isoindolic compound with a high yield. The method for manufacturing isoindolic compound comprises a thermal treatment step where a compound of which molecule includes a structure of pyrrole fused with bicyclo [2.2.2] octadiene skeleton is subjected to a supercritical carbon dioxide atmosphere. The thermal treatment step is preferably performed at a temperature of not less than 50° C. and not more than 300° C. | 2011-06-09 |
| 20110137025 | CHEMICAL FRAMEWORK COMPOSITIONS AND METHODS OF USE - The disclosure provides metal organic frameworks useful for sensing, gas sorption, microelectronics and switches. | 2011-06-09 |
| 20110137026 | Crystalline (6r,7r)-7--3- [(R)-1'-Tert-Butoxycarbonyl-2-Oxo-[1,3']Bipyrrolidinyl-(3e)-Ylidenemethyl- ]-8-Oxo-5-Thia-1-Aza-Bicyclo[4.2.0] Oct-2-Ene-2-Carboxylic Acid Benzhydryl Ester; Its Manufacture and Use - A solid DMSO solvate of a compound of formula (I) is described, which is a useful intermediate for preparing the broad spectrum antibiotics Ceftobiprole and Ceftobiprole Medocaril. | 2011-06-09 |
| 20110137027 | METHOD FOR PREPARING LACTAMES, COMPRISING A PHOTONITROSATION STEP, FOLLOWED BY A BECKMANN TRANSPOSITION STEP - The invention relates to a method for preparing lactames, according to which a photonitrosation of a cycloallcane is carried out using nitrosyl chloride (NOCI). According to the invention, said photonitrosation is carried out by means of LEDs emitting a monochromatic light. The method according to the invention can also include a step comprising Beckmann transposition/dechlorination of the oxime hydrochloride generated during said phonitrosation, preferably carried out in a glass microreactor. | 2011-06-09 |
| 20110137028 | METHODS OF SYNTHESIS AND PURIFICATION OF HETEROARYL COMPOUNDS - Provided herein are methods to prepare Heteroaryl Compounds having the following structure: | 2011-06-09 |
| 20110137029 | CATALYST AND PROCESS FOR PREPARING AN AMINE - A process for preparing an amine by reacting a primary or secondary alcohol, aldehyde and/or ketone with hydrogen and a nitrogen compound selected from the group of ammonia and primary and secondary amines, in the presence of a supported copper-, nickel- and cobalt-containing catalyst, wherein the catalytically active material of the catalyst, before the reduction thereof with hydrogen, comprises oxygen compounds of aluminum, of copper, of nickel, of cobalt and of tin, and in the range from 0.2 to 5.0% by weight of oxygen compounds of yttrium, of lanthanum, of cerium and/or of hafnium, each calculated as Y | 2011-06-09 |
| 20110137030 | CATALYST AND PROCESS FOR PREPARING AN AMINE - A process for preparing an amine by reacting a primary or secondary alcohol, aldehyde and/or ketone with hydrogen and a nitrogen compound selected from the group of ammonia and primary and secondary amines, in the presence of a supported copper-, nickel- and cobalt-containing catalyst, wherein the catalytically active material of the catalyst, before the reduction thereof with hydrogen, comprises oxygen compounds of aluminum, of copper, of nickel and of cobalt, and in the range from 0.2 to 5.0% by weight of oxygen compounds of tin, calculated as SnO, and catalysts as defined above. | 2011-06-09 |
| 20110137031 | PYRROLOPYRIMIDINE AND PYRROLOTRIAZINE DERIVATIVES - An object of the present invention is to provide an antagonist against CRF receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastral diseases, drug dependence, epilepsy, cerebral infarction, cerebral ischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alpecia, irritable bowel syndrome, sleep disorders, dermatitides, schizophrenia, pain, etc. A pyrrolopyrimidine or pyrrolotriazine derivative substituted with a carbamoyl group represented by the following formula [I]: has a high affinity for CRF receptors and is effective against diseases in which CRF is considered to be involved. | 2011-06-09 |
| 20110137032 | GPR119 AGONIST - A cyclic amine derivative represented by the formula (II) is a GPR119 agonist, and is used as an agent for treating diabetes. | 2011-06-09 |
| 20110137033 | PROCESS FOR PREPARING (4,6-DIMETHYLPYRIMIDIN-2-YL)PHENYLAMINE (PYRIMETHANIL) - A process for preparing (4,6-dimethylpyrimidin-2-yl)phenylamine (pyrimethanil) of the formula | 2011-06-09 |
| 20110137034 | PROCESS FOR PREPARING LAMIVUDINE POLYMORPH FORM - The invention relates to a process for the preparation of stable lamivudine polymorph form and to a composition comprising thereof. | 2011-06-09 |
| 20110137035 | PREPARATION OF MICROBIOLOGICALLY PRODUCED ERGOT ALKALOIDS - The present invention relates to a method for preparing microbiologically produced ergot alkaloids of the following formula (I), comprising the step of: a) extracting the fermentation product occurring during the biological production, said product containing at least one ergot alkaloid of formula (I), at a pH of 8-14 using an extractant with a solubility in water of 0.2 g/100 g of water to 25 g/100 g water at 20° C., wherein the amount of extractant is sufficient to form a 2-phase system together with the fermentation product. | 2011-06-09 |
| 20110137036 | SYNTHESIS OF (4aS,7aS)-OCTAHYDRO-1H-PYRROLO[3,4-b]PYRIDINE - The present invention relates to the stereoselective synthesis of (4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridine, as well as the conversion thereof, to give Moxifloxacin. Particularly, the present invention relates to a method for the synthesis of (4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridine of formula (I) comprising: (a) the optical resolution by enzymatic hydrolysis of the intermediate dialkyl-1-alkylcarbonylpiperidine-2,3-dicarboxylate racemate of formula (II) to give, following isolation, the intermediate dialkyl-(2S,3R)-1-alkylcarbonyl-piperidine-2,3-dicarboxylate of formula (III) in which AIk is a straight or branched C1-C5 alkyl group; (b) the conversion of the intermediate (III) to (4aR,7aS)-1-alkylcarbonylhexahydrofuro[3,4-b]pyridine-5,7-dione of formula (IV) in which AIk has the meanings set forth above; (c) the conversion of the intermediate (IV) to (4aS,7as)-octahydro-1H-pyrrolo[3,4-b]pyridine of formula (I) with an optical purity above 99%. | 2011-06-09 |
| 20110137037 | CASPASE INHIBITOR PRODRUGS - This invention relates to prodrugs of caspase inhibitors comprising of a furo[3,2-d]oxazolin-5-one moiety which, under specific conditions, can convert into biologically active compounds, particularly caspase inhibitors. | 2011-06-09 |
| 20110137038 | SYNTHESIS OF SELECTED STEREOISOMERS OF CERTAIN SUBSTITUTED ALCOHOLS - A process for producing one selected stereoisomer of a substituted alcohol comprises reacting a stereoisomeric epoxide with an amine, a carboxylic acid, an amide, a sulfonyl, or a cyanide. The process avoids the production of a racemic mixture of stereoisomers of the prior art. Such a stereoisomeric substituted alcohol can be used for anti-inflammatory therapy. | 2011-06-09 |
| 20110137039 | PROCESS FOR THE PREPARATION OF MONTELUKAST AND ITS SALTS - The present invention relates to an improved process for the preparation of 1-[[[(IR)-I-[3[(IE)-2-(7chloro-2-quino-linyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid and its salts using Methyl 2-[(3S)-[3-[(2E)-(7-chloro quinolin-2-yl)ethenyl]phenyl]-3-halopropyl]benzoate. | 2011-06-09 |
| 20110137040 | SYNTHESIS OF 3,4-DIARYL-4,5-DIHYDRO-(H)-PYRAZOLE-1-CARBOXAMIDINE DERIVATIVES - The invention relates to a novel chemical route to 3,4-diaryl-4,5-dihydro-(1H)-pyrazole-1-carbox-amidine derivatives, known as potent cannabinoid-CB | 2011-06-09 |
| 20110137041 | PROCESS FOR PREPARING ATOVAQUONE AND ASSOCIATE INTERMEDIATES - The invention provides novel intermediates of atovaquone and use thereof for the preparation of atovaquone | 2011-06-09 |
| 20110137042 | Process for Synthesis of Intermediates Useful for Making Substituted Indazole and Azaindazole Compounds - Disclosed are processes for preparing compounds of formula (I): | 2011-06-09 |
| 20110137043 | Process for the preparation of bidentate schiff base ruthenium catalysts containing a salicylaldimine-type ligand - The invention relates to a process for the preparation of bidentate Schiff base catalysts containing a salicylaldimine-type ligand. | 2011-06-09 |
| 20110137044 | ALTERNATIVE SYNTHESIS OF RENIN INHIBITORS AND INTERMEDIATES THEREOF - The present invention relates to synthetic routes to prepare a compound of the formula | 2011-06-09 |
| 20110137045 | BENZIMIDAZOLE DERIVATIVES - Provided herein are compounds in accord with Formula I: | 2011-06-09 |
| 20110137046 | PREPARATION METHOD OF (4S,5R)-SEMIESTER - A preparation method of (4S,5R)-semiester in which cycloanhydride conducts enantioselective ring-opening with alcohol in the presence of 9-epiquininurea. With this method, (4S,5R)-semiester is prepared at room temperature with high yield and high stereoselectivity. | 2011-06-09 |
| 20110137047 | Process for enantiomerically pure 8-Aryloctanoic acids as Aliskiren - The present invention relates to a novel manufacturing process and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially rennin inhibitors such as Aliskiren. The invention describes a preparation of enantiomerically pure 8-aryloctanoic acids of general formula I from readily available key intermediate, chiral cis-diacid of formula II, aziridine of formula XI and a monocyclic compound of formula III. | 2011-06-09 |
| 20110137048 | FUNCTIONALIZED N-SUBSTITUTED PYRROLIDONIUM IONIC LIQUIDS - This invention relates to compounds useful as ionic liquids that are based on an N-substituted pyrrolidinone and incorporate a pendant ammonium cation that is spaced from the pyrrolidone ring by a variable length linker. | 2011-06-09 |
| 20110137049 | CHIRAL IRIDIUM AQUA COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE HYDROXY COMPOUND USING THE SAME - The invention provides a chiral iridium aqua complex which has good preservation stability, can be easily produced, and enables asymmetric transfer hydrogenation in a higher yield and with higher stereoselectivity. The chiral iridium aqua complex has the formula (1A): | 2011-06-09 |
| 20110137050 | Process for the Preparation of 4,7-Dimethoxy-5-Methyl-1,3-Benzodioxole and Derivatives Thereof - Disclosed herein is a novel process for the preparation of a compound of formula (I), | 2011-06-09 |
| 20110137051 | PROCESS FOR RECOVERY OF FORMIC ACID - The invention relates to a process for the recovery of concentrated high purity formic acid having a concentration of at least 50%, most preferably at least 95%, from biomass wherein an aqueous liquid mixture containing levulinic acid and possibly furfural is subjected to a liquid-liquid extraction step, followed by the recovery of furfural, formic acid and levulinic acid. | 2011-06-09 |
| 20110137052 | Processes for the Preparation and Purification of Hydroxymethylfuraldehyde and Derivatives - A method for utilizing an industrially convenient fructose source for a dehydration reaction converting a carbohydrate to a furan derivative is provided. Recovery methods also are provided. Embodiments of the methods improve upon the known methods of producing furan derivatives. | 2011-06-09 |
| 20110137053 | PROCESS FOR PRODUCING ETHYLENE OXIDE - The present invention provides a process for producing ethylene oxide, comprising:
| 2011-06-09 |
| 20110137054 | PROCESS FOR THE MANUFACTURE OF A 1,2-EPOXIDE - The invention relates to a process for the manufacture of a 1,2-epoxide by catalytic oxidation of a terminal olefin with hydrogen peroxide wherein the catalytic oxidation is performed in a biphasic system comprising an organic phase and an aqueous reaction medium, wherein a water-soluble manganese complex is used as oxidation catalyst, wherein a terminal olefin is used with a solubility at 20° C. of at least 0.01 to 100 g in 1 liter water, and wherein the molar ratio of terminal olefin to hydrogen peroxide is in the range of from 1:0.1 to 1:2. | 2011-06-09 |
| 20110137055 | PROCESS FOR THE MANUFACTURE OF EPICHLOROHYDRIN - The invention relates to a process for the manufacture of epichlorohydrin (“ECH”)
| 2011-06-09 |
| 20110137056 | Chemical Process For Preparation Of Intermediates - The present invention relates to compounds useful as pharmaceutical intermediates, to processes for preparing the intermediates, to intermediates used in the processes, and to the use of the intermediates in the preparation of pharmaceuticals. In particular, the present invention concerns enantiomerically pure trans-cyclopropane carboxylic acid derivatives, processes for preparing the carboxylic acid derivatives and their use in preparing pharmaceuticals. | 2011-06-09 |
| 20110137057 | Unsaturated Steroid Compounds - The invention relates to methods to manipulate stem cells in vivo and in vitro to treat, e.g., a condition where cell or tissue repair is needed. | 2011-06-09 |
| 20110137058 | PREPARATION OF PARICALCITOL - This invention relates to a method for purifying Paricalcitol by reverse phase chromatography. This invention also relates to a purified Paricalcitol prepared by said method. This invention further relates to a method for purifying Paricalcitol by crystallization. | 2011-06-09 |
| 20110137059 | PROCESS FOR THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS, NOVEL CARBONYLATION LIGANDS AND CATALYST SYSTEMS INCORPORATING SUCH LIGANDS - A novel bidentate catalytic ligand of general formula (I) is described. R represents a hydrocarbyl aromatic structure having at least one aromatic ring to which Q | 2011-06-09 |
| 20110137060 | PREPARATION OF ANSA METALLOCENE COMPOUNDS - The present invention refers to a process for overcoming the problem of formation of oligomeric-polymeric complexes during preparation of cyclopentadienyl metallocenes comprising ligands bridged by at least three carbon atoms. According to the invention a process is presented comprising the steps of deprotonating a biscyclopentadienyl ligand bridged by a chain having a backbone of at least three carbon atoms by a base and reacting the deprotonated ligand with at least one alkali or alkaline earth metal alkylating agent and a salt of a transition metal belonging to group 3, 4, 5, 6 or to the lanthanide or actinide groups of the Periodic Table of the Elements. | 2011-06-09 |
| 20110137061 | NANOINK FOR FORMING ABSORBER LAYER OF THIN FILM SOLAR CELL AND METHOD OF PRODUCING THE SAME - A nanoink composition for forming an absorber layer of a thin film solar cell comprises particles and a volatile chelating agent mixing with the particles. The particles contain one or more elements selected from group IB and/or IIIA and/or VIA. In the present invention, the volatile chelating agent is a polyetheramine which can alternatively be monoamine compounds, diamine compounds and triamine compounds and has a molecular weight of from about 100 to about 4,000. Accordingly, the particles can be reacted mutually into a single composition while the existence of the volatile chelating agent. | 2011-06-09 |
| 20110137062 | SURFACE ENHANCED RAMAN SPECTROSCOPY USING SHAPED GOLD NANOPARTICLES - Surface enhanced Raman scattering (SERS) spectra of 4-mercaptobenzoic acid (4-MBA) self-assembled monolayers (SAMs) on gold substrates is presented for SAMs onto which gold nanoparticles of various shapes have been electrostatically immobilized. SERS spectra of 4-MBA SAMs are enhanced in the presence of immobilized gold nanocrystals by a factor of 10 | 2011-06-09 |
| 20110137063 | COMPOUNDS AND PROCESSES FOR PRODUCTION OF RADIOPHARMACEUTICALS - The present invention relates to novel perfluorinated precursors for the production of F-18 labeled radiotracers for Positron Emission Tomography (PET) and processes for radiolabeling and purification using these precursors. The invention also comprises radiopharmaceutical kits using these precursors and processes. | 2011-06-09 |
| 20110137064 | METHACRYLATE-BOUND PHOTOISOMERIZABLE CHROMOPHORE, METHODS FOR ITS SYNTHESIS - The invention discloses novel dicyanostilbene derivatives bound to a methacrylic moiety that can serve as an active chromophore in a 3-dimensional optical memory, processes for its synthesis and its intermediates. | 2011-06-09 |
| 20110137065 | PROCESSES FOR SYNTHESIZING 1-(2-ETHYLBUTYL)CYCLOHEXANE CARBONITRILE - Processes are provided for synthesizing substituted cyclohexane carbonitriles, particularly 1-(2-ethylbutyl)cyclohexane carbonitrile. Such processes comprise deprotonizing cyclohexane carbonitrile with chloro magnesium N,N-diisopropylamide and alkylating the deprotonated cyclohexane carbonitrile in the presence of 2-(ethylbutyl) bromide to produce 1-(2-ethylbutyl)cyclohexane carbonitrile. | 2011-06-09 |
| 20110137066 | PROCESS OF INHIBITING POLYMERIZATION OF ISOCYANATE GROUP-CONTAINING, ETHYLENICALLY UNSATURATED CARBOXYLATE COMPOUNDS, AND PROCESS FOR PRODUCING THE COMPOUNDS - It is an object of the invention to provide a process of inhibiting polymerization of isocyanate group-containing, ethylenically unsaturated carboxylate compounds, and a process for producing isocyanate group-containing, ethylenically unsaturated carboxylate compounds which involves the polymerization inhibition process. The process of inhibiting polymerization of isocyanate group-containing, ethylenically unsaturated carboxylate compounds of the invention includes controlling the oxygen gas (O | 2011-06-09 |
| 20110137067 | METHOD FOR PRODUCING URETHANES COMPOSED OF DI-FUNCTIONAL AROMATIC AMINES AND DIALKYL CARBONATES - A process for preparing urethanes by reacting aromatic diamines with a dialkyl carbonate, wherein the alkyl radical of the organic dialkyl carbonate comprises 2-18 carbon atoms and one or more heteroatoms and the reaction is performed in the presence of a catalyst. | 2011-06-09 |
| 20110137068 | METHOD FOR PRODUCING AMIDE DERIVATIVE - An amide derivative represented by Formula (3), which exhibits excellent efficacy in pest control effect, is produced by allowing a compound represented by the following Formula (1) and a compound represented by Formula (2) to react with each other. In Formula (1) to Formula (3), Y | 2011-06-09 |
| 20110137069 | METHOD FOR PRODUCING BIPHENYLTETRACARBOXYLIC ACID TETRAESTER - Disclosed is a method for producing a biphenyltetracarboxylic acid ester by oxidative coupling a phthalic acid ester by using a catalyst comprising at least a palladium salt, a copper salt and a β-dicarbonyl compound in the presence of a molecular oxygen, wherein the β-dicarbonyl compound is supplied into a reaction mixture liquid intermittently at an interval of less than 30 minutes, or continuously. This method allows, in particular, the selective and economical production of an asymmetric biphenyltetracarboxylic acid tetraester such as 2,3,3′,4′-biphenyltetracarboxylic acid tetraester. | 2011-06-09 |
| 20110137070 | PROCESS FOR PRODUCTION OF BICYCLO[2.2.2]OCTYLAMINE DERIVATIVE - The present invention herein provides a process for production of a bicyclo[2.2.2]octylamine derivative which may be used as an intermediate for preparation of medical and pharmaceutical products. The process is quite efficient and can produce the derivative in a large-scale while using mild reaction conditions. | 2011-06-09 |
| 20110137071 | Processes Related To The Hydroformylation Of Butenes - Mixed butene streams containing butene-1 and isobutylene and optionally butene-2 are hydroformylated under conditions that hydroformylates all the monomers to yield a mixture of valeraldehydes | 2011-06-09 |
| 20110137072 | METHOD FOR PRODUCING (METH)ACRYLIC ANHYDRIDE, METHOD FOR STORING (METH)ACRYLIC ANHYDRIDE, AND METHOD FOR PRODUCING (METH)ACRYLATE - It is an object of the present invention to provide a method for producing (meth)acrylic anhydride that provides high yield and high efficiency and can suppress side reactions, in a method for reacting (meth)acrylic acid with a fatty acid anhydride to produce (meth)acrylic anhydride. The method for producing (meth)acrylic anhydride according to the present invention is a method for producing (meth)acrylic anhydride, including reacting a fatty acid anhydride with (meth)acrylic acid to produce (meth)acrylic anhydride, while extracting a fatty acid produced as a by-product, wherein the reaction is performed, while adjustment is performed so that a molar ratio of the (meth)acrylic acid to the (meth)acrylic anhydride in a reaction liquid is 0.3 or more. | 2011-06-09 |
| 20110137073 | Process for Producing Alpha-Substituted Norbornanyl Acrylates - Disclosed is a process for producing α-substituted norbornanyl acrylates efficiently on an industrial scale while suppressing the formation of by-products derived from intramolecular cyclization, excessive addition to acrylic acid etc. The α-substituted norbornanyl acrylates are useful as norbornene resist monomers. In the disclosed process, an α-substituted acrylic acid is directly reacted with a substituted norbornene in the presence of at least one acid catalyst selected from methanesulfonic acid and camphorsulfonic acid. It is possible in this reaction to suppress the formation of the by-products derived from intramolecular cyclication, excessive addition of the acid to the reaction product etc. | 2011-06-09 |
| 20110137074 | PROCESS FOR THE PRODUCTION OF ACETIC ACID ETHYLENE AND VINYL ACETATE MONOMER - An integrated process for the production of acetic acid, ethylene and vinyl acetate monomer comprising the steps of:
| 2011-06-09 |
| 20110137075 | Vinyl acetate production process - A process for the production of vinyl acetate is disclosed. The process comprises reacting ethylene, acetic acid, and oxygen in the presence of a catalyst to produce a reaction mixture comprising vinyl acetate, ethylene, carbon dioxide, acetic acid, water and ethylene glycol diacetate. The reaction mixture is separated to a gas stream comprising ethylene, and carbon dioxide and a crude vinyl acetate stream comprising vinyl acetate, acetic acid, water and ethylene glycol diacetate. An ethylene glycol diacetate stream is isolated from the crude vinyl acetate stream and subjected to a reactive distillation to recover acetic acid. | 2011-06-09 |
| 20110137076 | Biological Buffers with Wide Buffering Ranges - Amines and amine derivatives that improve the buffering range, and/or reduce the chelation and other negative interactions of the buffer and the system to be buffered. The reaction of amines or polyamines with various molecules to form polyamines with differing pKa's will extend the buffering range, derivatives that result in polyamines that have the same pKa yields a greater buffering capacity. Derivatives that result in zwitterionic buffers improve yield by allowing a greater range of stability. | 2011-06-09 |
| 20110137077 | PROCESS AND APPARATUS FOR OXIDIZING ORGANIC COMPOUNDS - The invention relates to a process for oxidizing at least one organic substance with oxygen, which comprises the following steps:
| 2011-06-09 |
| 20110137078 | Catalyst And Method For Producing Unsaturated Aldehyde And Unsaturated Carboxylic Acid - Provided is a catalyst which can prevent a lowering in selectivity for a target product in a gas phase catalytic reaction and has an excellent frictional resistance. A catalyst which is a supported catalyst comprising an inert support that is coated with a catalyst powder, characterized in that the inert support is ring-shaped and has an outer periphery that is curved in the lengthwise direction of the support, and the catalyst is produced by granulation in a moisten environment. The above described catalyst is useful in the gas phase oxidation of propylene, isobutylene, tertiary-butyl alcohol or methyl tertiary-butyl ether to thereby produce an unsaturated aldehyde corresponding thereto, or in the gas phase oxidation of such an unsaturated aldehyde as described above to thereby produce an unsaturated carboxylic acid. | 2011-06-09 |
| 20110137079 | METAL OXIDE-CHELATING LIGANDS - A compound having the formula below. The values n and m are independently selected positive integers. | 2011-06-09 |
| 20110137080 | PROCESS AND APPARATUS FOR RECOVERY OF ACETIC ACID FROM A FEED STREAM CONTAINING THE CORRESPONDING ESTER - An apparatus and process for recovery of a carboxylic acid e.g. acetic acid, from an aqueous feed stream containing the corresponding ester, an alcohol and a small amount of water, and in some cases the carboxylic acid includes a catalytic distillation column containing an acidic catalyst and a distillation column. The alcohol is catalytically dehydrated to the corresponding ether and water, and the water reacts with the ester to generate a liquid carboxylic acid rich product stream. The acid is recovered by distillation in the distillation column. In a second embodiment, additional methanol and/or water are co-fed with the feed or fed directly to the catalytic distillation column, resulting in a liquid bottoms product stream of substantially pure acetic acid and a tops distillate stream of substantially pure ether. | 2011-06-09 |
| 20110137081 | Continuous Method For Producing Amides Of Low Aliphatic Carboxylic Acids - The invention relates to a continuous method for producing amides, according to which at least one carboxylic acid of formula (I) | 2011-06-09 |
| 20110137082 | CHARGE-ENHANCING ADDITIVES FOR ELECTRETS - Materials are disclosed which can enhance the electrostatic charge of electret materials. The materials comprise N-substituted amino carbocyclic aromatic compounds of the formula R1R2N—Ar(G)n where Ar is an aryl group, the group R1 is hydrogen, alkyl, alkenyl, alkynyl, aryl, heteroalkyl or substituted alkyl, alkenyl, alkynyl, the group R2 is alkyl, alkenyl, alkynyl, aryl, heteroalkyl or substituted alkyl, and each G is independently hydrogen, alkyl, alkenyl, alkynyl, aryl, heteroalkyl, substituted alkyl, or —NR3R4 where each R3 is independently hydrogen, alkyl, alkenyl, alkynyl, aryl, heteroalkyl or substituted alkyl, and each R4 is independently alkyl, alkenyl, alkynyl, aryl, heteroalkyl or substituted alkyl, and Ar is a phenyl group when n is 5, a naphthalene group when n is 7, and an anthracene group when n is 9. | 2011-06-09 |
| 20110137083 | CONTINUOUS METHOD AND REACTOR FOR HYDROGENATING ORGANIC COMPOUNDS - The present invention relates to a continuous process for hydrogenating organic compounds in a polyphasic system in the presence of a homogeneous or heterogeneous catalyst, which comprises performing the process in two stages, the first stage being performed in a loop reactor with an external heat exchanger and the second stage in a bubble column reactor with limited backmixing. | 2011-06-09 |
| 20110137084 | METHOD FOR PRODUCING PURE OR ENRICHED Q10 COENZYME - The present invention relates to a method for isolating coenzyme Q | 2011-06-09 |
| 20110137085 | NOVEL METHOD FOR THE CONVERSION OF CELLULOSE AND RELATED CARBOHYDRATE MATERIALS TO LOW-MOLECULAR-WEIGHT COMPOUNDS - Methods of converting cellulose or related biorenewable carbohydrate materials into high-value chemical compounds. The methods provide a means of converting low-cost materials such as cellulose and biomass into high yields of compounds such as ethylene glycol, propylene glycol, glycerin, methanol, hydroxyacetone, glycolaldehyde and dihydroxyacetone. | 2011-06-09 |
| 20110137086 | PROCESS FOR TELOMERIZATION OF BUTADIENE - In an improved process for telomerizing butadiene, contact butadiene and an organic hydroxy compound represented by formula ROH (I), wherein R is a substituted or unsubstituted C | 2011-06-09 |
| 20110137087 | METHOD OF REDUCING METHANOL IN RECYCLE STREAMS IN BISPHENOL-A PRODUCTION PROCESS - Methods for removing methanol from acetone recycle streams during bisphenol-A production, thereby avoiding the deactivation of catalyst, by distilling an acetone-methanol-water comprising mixture such that acetone is taken overhead in form of a relatively pure distillate, and substantial portions of the methanol and the water are leaving with the bottom product. | 2011-06-09 |
| 20110137088 | Methods and Apparatuses for Producing Renewable Materials From Inhibiting Compounds - Renewable materials made from inhibiting compounds. A method includes the step of consuming a fermentation inhibiting compound with a biological organism, and the step of producing a renewable material with the biological organism from at least a portion of the fermentation inhibiting compound. The methods may include a net balance of cofactor production and consumption. | 2011-06-09 |
| 20110137089 | PROCESS FOR INCREASING HYDROGEN CONTENT OF SYNTHESIS GAS - A process for increasing the hydrogen content of a synthesis gas containing one or more sulphur compounds is described, comprising the steps of (i) heating the synthesis gas and (ii) passing at least part of the heated synthesis gas and steam through a reactor containing a sour shift catalyst, wherein the synthesis gas is heated by passing it through a plurality of tubes disposed within said catalyst in a direction co-current to the flow of said synthesis gas through the catalyst. The resulting synthesis gas may be passed to one or more additional reactors containing sour shift catalyst to maximise the yield of hydrogen production, or used for methanol production, for the Fischer-Tropsch synthesis of liquid hydrocarbons or for the production of synthetic natural gas. | 2011-06-09 |
| 20110137090 | PROCESS FOR PREPARING 2,3,3,3-TETRAFLUOROPROPENE AND 1,3,3,3-TETRAFLUOROPROPENE - The present invention provides a process for preparing 2,3,3,3-tetrafluoropropene represented by CF | 2011-06-09 |
| 20110137091 | Manufacture of Oligomers from Nonene - In oligomerizing alpha-olefins to produce poly alpha-olefins, the feedstock consists of nonene, or a blend of alpha-olefins comprising nonene. The nonene comprising alpha-olefin feedstock and at least one catalyst are subjected to oligomerization or polymerization conditions in a reactor. Following reaction, the mixture may be subjected to distillations to removed unreacted alpha-olefins and dimers of the alpha-olefins. The resulting product may also be hydrogenated. The final product may also be fractioned to recover at least two fractions of poly alpha-olefins of differing nominal viscosities. | 2011-06-09 |
| 20110137092 | Aromatization Catalyst Comprising Prolongated Silica and Methods of Making and Using Same - A prolongated silica bound zeolite support comprising from about 85 wt % to about 95 wt % zeolite. A catalyst composition comprising a prolongated silica bound zeolite supporting at least one Group VIII metal and at least one halide. A process of making a prolongated silica bound zeolite support comprising mixing a zeolite, a prolongated silica, and water to form a mixture, and shaping the mixture into the prolongated silica bound zeolite support. A process of making a prolongated silica bound zeolite catalyst comprising mixing a zeolite, a prolongated silica, and water to form a mixture, shaping the mixture into a prolongated silica bound zeolite support, and adding one or more catalytic compounds to the prolongated silica bound zeolite support to form the prolongated silica bound zeolite catalyst. A process for converting hydrocarbons to aromatics comprising: contacting a prolongated silica bound zeolite catalyst comprising at least one Group VIII metal and at least one halide with a hydrocarbon feed in a reaction zone under aromatization conditions; recovering an aromatic product from the reaction zone; and purifying the aromatic product to produce benzene, toluene, paraxylene, orthoxylene, metaxylene, or combinations thereof. | 2011-06-09 |
| 20110137093 | ENHANCING CATALYTIC ACTIVITY OF NANOPOROUS MATERIALS - The present invention relates to the use of atomic layer deposition (ALD) techniques to enhance the acid catalytic activity of nanoporous materials. | 2011-06-09 |
| 20110137094 | PROCESS FOR PRODUCING ETHYLIDENE NORBORNENE - Process for producing ethylidenorbornene (ENB) comprising a stage of thermal cracking of DCPD to CPD carried out in an inert fluid to which it is fed a stream of DCPD comprising virgin DCPD from cracking containing up to 10% wt of tetrahydroindene (THI) and recycled DCPD containing THI coming from the subsequent stage of formation of vinylnorbornene. The contact time of DCPD with the heat transfer fluid is of few seconds and it is sufficient to achieve a conversion of said DCPD ≧95%, with little formation of oligomers. THI is then separated from the heat transfer fluid substantially free from DCPD and enriched in THI to a fractionation column. | 2011-06-09 |
| 20110137095 | PROCESS FOR PRODUCING OLEFINS - The present invention provides a process for producing olefins, comprising:
| 2011-06-09 |
| 20110137096 | Process to Make Olefins from Ethanol - The present invention relates to a process for the conversion of ethanol to make essentially ethylene and propylene, comprising:
| 2011-06-09 |
| 20110137097 | PROCESS FOR ISOMERIZING A SATURATED, BRANCHED AND CYCLIC HYDROCARBON - A process for isomerizing a saturated, branched and cyclic hydrocarbon, in which a tertiary carbon atom of the hydrocarbon is converted to a secondary carbon atom in the course of isomerization, by performing the isomerization in the presence of a superacidic ionic liquid comprising an organic cation and an inorganic anion, where the anion is a superacidic aluminum trichloride-Lewis base adduct, and of a copper(II) compound. | 2011-06-09 |
