23rd week of 2011 patent applcation highlights part 50 |
Patent application number | Title | Published |
20110136597 | INFLATABLE GAME STRUCTURE - A game apparatus including at least one rebound surface upon which a player can jump, flexible material extending substantially vertically up from the at least one rebound surface dividing the at least one rebound surface into at least two individual play areas having the at least one rebound surface as a floor, an opening between the play areas a preset distance above the rebound surface to allow a play object to move between play areas includes an inflatable flexible material mounting frame supporting the flexible material. An inflatable rebound surface mounting frame can also be provided for supporting the rebound surface. | 2011-06-09 |
20110136598 | ELECTRONIC MARKER STAKES FOR SPORTS FIELDS - A marker stake for locating a boundary reference point on a sports field can be buried and out of sight when not in use, and then quickly located using an electronic receiver which detects a signal emitted by an electronic marker in the marker stake. Various field boundary indicators can be removably attached to the marker stake. The stake may be embodied in a cylindrical body constructed of a moldable polymer with a socket at one end for receiving a pin or post of the field boundary indicator, and the electronic marker embedded inside the body. The electronic marker may be a passive LC marker tuned to a frequency associated with a known field sport. Different sets of such marker stakes tuned to different frequencies may be used to mark and relocate reference points for multiple sports played on the same field. | 2011-06-09 |
20110136599 | LACROSSE STICK - A lacrosse head comprising a base portion including a shaft socket and a ball stop. A pair of divergent arms extending from the base portion and a sidewall that extends from each of the divergent arms at a corresponding junction. The junction between each divergent arm and its associated sidewall forming a discontinuity. The head may include a rim that extends around a scoop region and a throat region of the lacrosse head. The rim may join the base portion on either side of the ball stop at a location aligned with a centerline of the shaft socket. The ball stop protrudes into the throat region between the divergent arms in order to help prevent the ball from being wedged in the throat region. The base portion may include the ball stop, wherein the ball stop is in the form of a convex protrusion. | 2011-06-09 |
20110136600 | LACROSSE HEAD HAVING A BALL STOP - A lacrosse head includes a ball stop having a bottom and side regions that transition at transition regions to head sidewalls, which are joined with a scoop of the head. The ball stop can include a longitudinal axis that extends toward the scoop. The transition regions can be located on a horizontal axis generally perpendicular to the longitudinal axis. At a distance less than or equal to 1.25 inches from the bottom along the longitudinal axis, opposing side regions and/or sidewalls are separated by a minimum width of 3 inches from the bottom. This construction provides a generally v-shaped ball stop that complies with proposed 2010 NCAA Lacrosse Rules regarding the dimensional requirements for a lacrosse head, while providing improved ball retention within the lacrosse head. | 2011-06-09 |
20110136601 | RACKET STRING AND METHOD FOR PRODUCING THE SAME AND RACKET STRUNG WITH THE SAME - A racket string | 2011-06-09 |
20110136602 | FIBER COMPOSITE AND PROCESS OF MANUFACTURE - The inventive fiber manufacturing process is particularly adapted for demanding applications such as sports racquets, including tennis racquets, badminton racquets and other sports applications. Because of the improved strength to weight ratio of components formed using the inventive method, a wide range of flexibility is achieved, allowing use of the inventive process to manufacture, for example, a fiber reinforced (for example, graphite) modular sports racquet, optionally provided with user-selectable weights and/or handle replacements. From the standpoint of the player, this allows a racquet frame featuring self customization. From the standpoint of a retailer, the benefit provided is reduction of inventory. The inventive fiber, for example graphite fiber) racquet frame is filled with a plastic foam and is formed using, for example, microencapsulation technology to time, generate and apply the pressure used to form the graphite composite material of which the racquet is comprised. Advantageously, inner and outer tubular members may be used to form the racquet frame, with the inner tubular member extending around the head of the racquet frame. This compares to the standard industry technique of air injection. The racquet is thus not hollow like conventional graphite racquets, and the walls therefore can be made thinner than those of existing graphite racquets still being of the same strength or being stronger, which gives the racquet exceptional performance. In addition, the overall dimensions of, for example the cross-section, of the racquet can also be reduced while still maintaining performance characteristics. | 2011-06-09 |
20110136603 | sOccket - Our invention hybridizes ‘ball sports,’ including soccer, baseball, tennis, and etc., and devices converting mechanical energy (through impact or shaking) to produce power while playing or participating in sports. Modifications include embedding sensors into a ball to identify the degree of kicking or hitting, or utilize them in the context of other computer or AV-based games. | 2011-06-09 |
20110136604 | Ball body - This invention relates to a ball body which essentially comprises a transmitting hollow inner bladder. A recessed socket for accommodation of a vibration-powered luminous body is provided on the transmitting hollow inner bladder. A superficial layer is further wrapped on outside surface of the transmitting hollow inner bladder, which has transmitting areas provided thereon. When the ball body is played to produce vibration, the vibration-powered luminous body is lightened and light is scattered out through the transmitting hollow inner bladder and the transmitting areas on the superficial layer so as to increase more fun in playing the ball and diversified functions of toy. | 2011-06-09 |
20110136605 | DUAL PLUNGER LINEAR CHAIN TENSIONER FOR TENSIONING MULTIPLE CHAIN SPANS - A chain tensioner is provided with a base housing, a first plunger, and a second plunger. The base housing surrounds a portion of at least one of the first or second plungers. A first spring is disposed between the first and second plungers, and a second spring is disposed between the first plunger and the base housing. The chain tensioner can tension two chain spans simultaneously with different stiffness parameters based on the two springs. | 2011-06-09 |
20110136606 | CHAIN-SPROCKET MECHANISM, CHAIN AND SPROCKET - A chain-sprocket mechanism is disclosed which is highly resistant to corrosion caused by a potential difference arising when metallic materials of different types contact each other. A chain of the chain-sprocket mechanism is structured by coupling a plurality of chain links that consist of pairs of outer plates, pairs of inner plates, bushings fixed to the inner plates and pins inserted through the outer plates, the inner plates and the bushing, which meshes with teeth of a sprocket. The surface of either of the bushing or the teeth is formed of a non-metallic material; thereby, a potential difference does not arise through the contact between the bushing and the teeth. Accordingly, corrosion caused by a potential difference can be avoided, i.e., the corrosion resistance of the chain-sprocket mechanism can be improved. | 2011-06-09 |
20110136607 | SYNCHRONIZER IN ELECTRO-MECHANICAL TRANSMISSION - An electro-mechanical transmission includes a plurality of transmission components and at least one synchronizer configured to selectively engage and disengage at least two of the transmission components to effect operation in a speed range in the transmission. The synchronizer further includes a plurality of input components associated with one of the transmission components and a plurality of output components including a clutching mechanism configured to engage to at least one of the input components when the synchronizer is activated and disengage from the input component when the synchronizer is deactivated. | 2011-06-09 |
20110136608 | HYDRAULIC CONTROL SYSTEM OF POWER TRAIN FOR HYBRID VEHICLE - The present invention provides a hydraulic control system of a power train for a hybrid vehicle that allows the power train of a hybrid vehicle to implement all of two or more EV modes, two or more power split modes, and at least three or more fixed-stage modes, with a relatively simple configuration, and achieves satisfactory power performance of the power train and fuel efficiency and reduce the cost of the valve body, remove possibility of malfunction, and implements a limp home function when a controller is broken. | 2011-06-09 |
20110136609 | DRIVE TRAIN FOR A MOTOR VEHICLE - A drive train for a motor vehicle, which has a first and a second axle. The drive train has a first drive unit for permanently driving the first axle and an electric drive unit, which is arranged in the region of the second axle and has an electric motor. A shift clutch package contains a first shift clutch for setting up a first transmission ratio and a second shift clutch for setting up a second transmission ratio between the electric motor and an output of the electric drive unit. The electric drive unit is arranged parallel to an input shaft of a transverse differential of the second axle. | 2011-06-09 |
20110136610 | ACTUATOR FOR OPERATING A DIFFERENTIAL LOCK - An actuator for operating a differential lock includes a chassis, a first motor mounted on the chassis and including a first motor pinion, a second motor mounted on the chassis and including a second motor pinion, and a ring gear rotatably mounted on the chassis about a ring gear axis and having a ring gear thread defined about the ring gear axis. The actuator includes an actuator element having an actuator element thread in engagement with the ring gear thread and having a feature for preventing rotation of the actuator element thread, the first motor pinion and second motor pinion being operable to drive the ring gear. | 2011-06-09 |
20110136611 | DIFFERENTIAL LOCK WITH ASSISTED RETURN - A differential lock mechanism includes a shift member and a shift collar that is moveable by the shift member between an engaged position with a differential assembly and a disengaged position. A pneumatic control provides a first pneumatic signal to move the shift collar into the engaged position and provides a second pneumatic signal to return the shift collar to the disengaged position. | 2011-06-09 |
20110136612 | AXLE ASSEMBLY METHOD - A torque transmitting component that includes a hollow adjuster that is employed to preload and/or position a bearing that supports a differential assembly relative to a housing. One of the housing and the adjuster includes a first engagement feature and the other one of the housing and the adjuster includes a second engagement feature. A retaining member is press-fit to the first engagement feature and is non-rotatably coupled to the second engagement feature to inhibit rotation of the adjuster relative to the housing. A method is also provided. | 2011-06-09 |
20110136613 | COMPACT TRANSMISSION COMPRISING A PLANETARY GEAR SET - A transmission has a housing and two input/output shafts. Inside the housing is a planetary gear set with three rotatable members which are connected to the housing and the two input/output shafts. Inside the housing is a clutch which can connect two out of three of the rotatable members. When the clutch is closed the input/output shafts are connected together one to one. The pressure plate of the clutch is connected to a brake disc of a brake system that is connected to one of the rotatable members. When the brake system is closed the input/output shafts are connected via the planetary gear set. The transmission further includes a lever which can move the brake disc in axial direction and can thus open the clutch during operation. | 2011-06-09 |
20110136614 | MULTI-SPEED TRANSMISSION HAVING THREE PLANETARY GEAR SETS - A transmission is provided having an input member, an output member, three planetary gear sets, a plurality of coupling members and a plurality of torque transmitting devices. Each of the planetary gear sets includes first, second and third members. The torque transmitting devices include clutches and brakes. | 2011-06-09 |
20110136615 | MULTI-SPEED TRANSMISSION - A transmission is provided having an input member, an output member, four planetary gear sets, a plurality of coupling members and a plurality of torque transmitting devices. Each of the planetary gear sets includes first, second and third members. The torque transmitting devices may include clutches and brakes. | 2011-06-09 |
20110136616 | AUTOMATIC TRANSMISSION - An automatic transmission including a single-pinion first planetary gearset having a first sun gear, a first ring gear and a first pinion carrier, a double-pinion second planetary gearset having a second sun gear, a second ring gear and a second pinion carrier, a single-pinion third planetary gearset having a third sun gear, a third ring gear and a third pinion carrier, an input shaft always connected to the first sun gear, an output shaft always connected to the first pinion carrier, the third sun gear always kept in a fixed state, the first ring gear and the second sun gear which are always connected to each other, the second and third ring gears which are always connected to each other, and six friction elements, at least eight forward speeds and one reverse speed being respectively established by simultaneous engagement of two friction elements selected from the six friction elements. | 2011-06-09 |
20110136617 | Planetary Gear Assembly - A planet gear assembly, including: a planet pin; a bearing comprising an inner race secured to the planet pin at a planet pin bearing end; a planet gear; and a compliant annular plate arranged to secure the planet gear to the planet pin. Compliance of the annular plate permits rotation of the planet gear when a planet gear axis of rotation is not coincident with an axis of rotation of a portion of the planet pin in the annular plate. | 2011-06-09 |
20110136618 | POWER TRANSMISSION APPARATUS FOR A BICYCLE - The present invention relates to a bicycle driving apparatus, and more particularly, to a bicycle driving apparatus which enables the forward travel of the bicycle regardless of the forward rotation or reverse rotation of the pedals. The bicycle driving apparatus according to the present invention enables a bicycle to travel in the forward direction not only when a pedal rotates in the forward direction but also when the pedal rotates in the reverse direction. | 2011-06-09 |
20110136619 | SPEED INCREASING/DECREASING APPARATUS - A first rotary shaft and a second rotary are disposed such that they are rotatable around a rotation axis. The second rotary shaft has a cylindrical supporting part that covers the end section of the first rotary shaft. A case supports the first rotary shaft and the second rotary shaft. A first rolling bearing is disposed between the first rotary shaft and the case and supports the first rotary shaft such that it is rotatable. A second rolling bearing is disposed between the supporting part and the first rotary shaft and supports the first rotary shaft and the second rotary shaft such that they are rotatable relative to each other. A transmission part of the second rotary shaft transmits to the second rolling bearing a preload force that pushes the second rotary shaft to the first rotary shaft side. A load-receiving part of the case that receives the preload force transmitted from the second rolling bearing to the first rolling bearing. | 2011-06-09 |
20110136620 | METHODS AND SYSTEMS FOR ASSISTED DIRECT START CONTROL - Methods and systems are provided for controlling a vehicle engine coupled to a stepped-gear-ratio transmission. One example method comprises, in response to a first vehicle moving condition, shutting down the engine and at least partially disengaging the transmission while the vehicle is moving; and during a subsequent restart, while the vehicle is moving, starting the engine using starter motor assistance and adjusting a degree of engagement of a transmission clutch to adjust a torque transmitted to a wheel of the vehicle. | 2011-06-09 |
20110136621 | METHODS AND SYSTEMS FOR ASSISTED DIRECT START CONTROL - Methods and systems are provided for reducing driveline unwinding during successive engine shutdown and restart operations. In one example, during an engine shutdown, torsion is maintained in a transmission gear-train until an engine restart is requested by engaging one or more transmission clutches while applying wheel brakes. | 2011-06-09 |
20110136622 | CONTROL APPARATUS FOR INTERNAL COMBUSTION ENGINE - Provided is a control apparatus for an internal combustion engine, which quietly restarts the engine with a reduced torque shock when a re-acceleration request is made by a driver. A control apparatus for an internal combustion engine, for controlling a clutch provided between the internal combustion engine and an automatic transmission, includes: an accelerator opening-degree detection unit for detecting a pressing amount of an accelerator; a fuel-supply stopping unit for stopping fuel injection to the internal combustion engine when the accelerator is not pressed down; and a clutch direct-coupling ratio control unit capable of arbitrarily changing a power amount transmitted by the clutch from engagement for direct coupling to disengagement of the clutch, in which, when the accelerator is pressed down while the clutch is disengaged in a fuel-supply stop state, the clutch is engaged in a slipping manner so that internal combustion engine rpm becomes equal to or higher than target cranking rpm to restart the internal combustion engine. | 2011-06-09 |
20110136623 | METHOD FOR POSITIONING AN ENGINE - A method for positioning an engine, a clutch of a transmission of the engine being activated in a targeted manner and engaged in a controlled manner during the deceleration process of the engine. Also, a system for positioning an engine. | 2011-06-09 |
20110136624 | BRAKE SYSTEM FOR VEHICLE WITH IDLE STOP AND GO DEVICE AND CONTROL METHOD THEREOF - The present invention provides a brake system for a vehicle with an idle stop and go comprising a valve assembly disposed in a brake line for supplying brake pressure to the wheels by operation of the brake pedal to open or close the brake line; and a controller controlling the valve assembly. | 2011-06-09 |
20110136625 | Hybrid Electric Vehicle Hold Function - A vehicle powertrain with engine start-stop characteristics is capable of maintaining a vehicle stationary on a roadway with a gradient when wheel brakes are applied to stop the vehicle as the engine is shut down. Vehicle creep and vehicle launch is achieved as the engine is re-started following detection of a brake release signal based on engine speed. | 2011-06-09 |
20110136626 | System for Training and Evaluating Bilateral Symmetric Force Output of Upper Limbs - A system for training and evaluating bilateral symmetric force output of upper limbs has a force application unit of bilateral upper limbs, a movable link unit, a signal conversion unit, a computing unit and a driving unit. The force application unit of bilateral upper limbs has at least two force sensors. When stroke patients perform training, the system can instantaneously measure values of forces exerted by users and sensed by the sensors, and determine if the movable link unit is driven according to a pre-configured training pattern, so that both hands of patients are allowed to perform training movements pushing forward and pulling backward to promote training mechanism of dual-brain hemisphere organization and improve moving capability of upper limb of affected side. | 2011-06-09 |
20110136627 | EXERCISE DERIVED CURRENCY FOR EXCHANGE OR GRADING - According to various embodiments of the invention, systems and methods are provided to allow a mobile computing device to retrieve exercise related data from a health or fitness monitoring device during an exercise period. The mobile computing device is further configured to use the exercise related data to determine a number of points or an amount of currency earned during the exercise period. These points may then be exchanged for privileges, grades or financial rewards. In some embodiments, this exchange may be conducted or mediated using a system embodied on a second mobile computing device or servers on the internet. | 2011-06-09 |
20110136628 | EXERCISE METHODS AND APPARATUS - An exercise apparatus links rotation of a crank to generally elliptical motion of a foot supporting member. A foot supporting linkage is movably connected between a rocker and a crank in such a manner that the foot supporting member moves through paths of motion which are fixed, adjustable or variable. | 2011-06-09 |
20110136629 | Swimming exercising device - Individual swimmers may routinely and easily perform exercise regiments to maintain or enhance their general health and fitness utilizing the present invention. A pole may be secured adjacent a body of water to retain a tether and a harness which retains the swimmer. Numerous pole mounting arrangements provide for deployment of the swimming exercise device with nearly any configuration of swimming pool without regard for whether the pool is of the in ground style or of the above ground style and without regard for size from the smallest available to Olympic size. A small but durable hand rail mount and a water filled anchor which merely sits adjacent the body of water provide for excellent securement of the pole without any structural modification to any existing structure. | 2011-06-09 |
20110136630 | Training Apparatus - Training apparatus arranged for supporting a bicycle, comprising a ground-supported or supportable frame that is at least provided with a supporting roll or rollers for a bicycle back wheel that are movable in the frame in vertical direction, wherein the suspension of said roll or rollers is arranged to convert relative horizontal movements of the roll or rollers into vertical movements thereby compensating and/or attenuating said horizontal movements by gravity. | 2011-06-09 |
20110136631 | VARIABLY CONFIGURED EXERCISE DEVICE - A variably configured exercise device is provided. The exercise device can include a vertical support member having a longitudinal axis, a sliding member configured to move along the vertical support member in a direction substantially parallel to the longitudinal axis, a pair of rails each having first and second end portions. The first end portion of each rail can be pivotally connected to the sliding member on the vertical support member. The exercise device can further include an actuation mechanism coupled to the sliding member where the actuation mechanism can be configured to selectively adjust the position of the sliding member relative to the vertical support member. | 2011-06-09 |
20110136632 | WEIGHTLIFTING SYSTEM - A weightlifting system includes a first frame member that extends along a longitudinal axis. The first frame member includes a front face, a first side face, a second side face and a multiple of opposed pairs of openings disposed along the longitudinal axis. Each of the multiple of opposed pairs of openings are generally L-shaped and include a first opening and a second opening. | 2011-06-09 |
20110136633 | EXERCISE APPARATUS - The invention is directed to an exercise apparatus comprising a resilient hoop, an inner perimeter surface of the hoop forming a circular opening while in a resting position. Coupled to the hoop at a first portion are a first grip and a second grip, each configured to accept one hand of a user, wherein the hoop is deformable to be elliptic when the first and second grips are supported inward from the first portion toward the center of the circular opening, while a second portion of the hoop rests against a user's body. | 2011-06-09 |
20110136634 | PORTABLE EXERCISE APPARATUS AND METHOD - The improved exercise apparatus comprises a housing assembly having first and second arm members. The apparatus may be used to perform a variety of full body exercises generally by moving the first and second arms about an axial stem of the housing assembly. In one embodiment, the arm members rotate or pivot about the axial stem. A tension assembly provides resistance to the movement of the arm members while a positioning assembly allows the arm members to be positioned and secured in various positions relative to one another. One or more handle attachments may be provided to allow the apparatus to be grasped or used in various ways. A method of training various portions of the body with the apparatus is also provided herein. | 2011-06-09 |
20110136635 | Supporting device for a person's back and head area - The invention relates to a supporting device for the back and head of a human being. Said device comprises a partial area of a back supporting section at the level of the shoulder blade, a central supporting surface in the region of a vertebral column and open areas which are arranged on the both sides of the central supporting surface in such a way that the shoulder blade regions can be lowered beyond the central supporting area. The invention can be used for furniture for the household or workplace. | 2011-06-09 |
20110136636 | BALANCE BOARD FOR PIPE ROLLER - A balance board includes an elongated, generally rigid board having a top surface, a bottom surface, and upwardly-angled distal ends and upwardly-angled side edges. The bottom surface of the board has a center plane that extends longitudinally between areas of the bottom surface proximate the upwardly-angled distal ends. The width of the center plane is defined by the upwardly-angled side edges. The bottom surface of the board is at least partially coated with a frictional material. A balance board system includes a cylindrical roller, preferably having a uniform cross-sectional size and shape along its length. The roller is formed of a smooth, rigid material. The system allows extreme tricks and moves by a rider of the board on the roller. | 2011-06-09 |
20110136637 | ROLLER FOR THE TREATMENT OF PAPER WEB MATERIAL - Roller for treating a paper web, particularly apt to be used within an embossing or a calendering unit, comprising a central fixed shaft ( | 2011-06-09 |
20110136638 | SLEEVE ROLL - The sleeve roll according to the present invention has the metallic sleeve | 2011-06-09 |
20110136639 | DEVICE AND METHOD FOR PROCESSING OF FILM TUBES TO OPEN-MOUTHED BAGS AND FOR FILLING SAME WITH BULK MATERIALS - Device and method for processing open-mouth bags with a bag opening device for opening an open-mouth bag and with a valve inserting device which is suitable and intended to insert a de-aeration valve into a bag wall of the open-mouth bag. | 2011-06-09 |
20110136640 | APPARATUS FOR FINISHING PRODUCTS COMING OUT FROM A MACHINE FOR FOLDING AND GLUING CARDBOARD OR PAPERBOARD PRODUCTS WITH A BACK - An apparatus for finishing products coming out from a folding and gluing machine of cardboard or paperboard products with a back, includes a longitudinal housing for advancing the products in rows, defined by two groups ( | 2011-06-09 |
20110136641 | PACKAGE BOX AND BOX FORMING MEMBER - A box forming member includes a plurality of surfaces parts which are configured to fold with respect to each other to form a package box. At least one of the surface parts has a first surface having a first design formed thereon, and a second surface opposite to the first surface and having a second design formed thereon, and the first design is different from the second design, such that the box forming member is foldable into two package boxes having different designs on the outside thereof. | 2011-06-09 |
20110136642 | BOX FOLDING APPARATUS - A box folding apparatus operable to close the top of a box having four flaps is provided. The boxing folding apparatus includes a worktable, a feeding assembly for transporting the box from an upstream position of the worktable to a downstream position of the worktable. A first folding assembly includes a rotatable folding arm, a second folding assembly includes a stationary resisting bar inclined toward the feeding assembly in the direction in which the box is transported, and a third folding assembly includes a first inclined surface and a second inclined surface intersecting with the first inclined surface. The first and second inclined surfaces extend toward and gradually close to the feeding assembly in the direction in which the box is transported. | 2011-06-09 |
20110136643 | Folder with Signature Support and Method - A method for folding signatures is provided. The method includes the steps of forcing a trail edge of a first signature away from a folding cylinder using a signature support, tucking a second signature held by a gripper using a tucker at a first fold location and performing a mode change to tuck a further signature at a second fold location different from the first fold location, the mode change including moving the gripper and the signature support automatically with respect to the tucker. A signature support is also provided. | 2011-06-09 |
20110136644 | SHEET FOLDING APPARATUS AND IMAGE FORMING APPARATUS USING THE SAME - A sheet folding apparatus includes: a fold roller pair which forms a nipping portion and inserts the center of a sheet bundle into the nipping portion to form a fold in the sheet bundle; a folding blade which moves from a standby position and presses the center of the sheet bundle against the nipping portion when the fold is formed, and returns to the standby position after the pressing of the nipping portion is completed; and a protection member which prevents an access to a front edge of the folding blade in a longitudinal direction of the front edge when the folding blade is located at the standby position. | 2011-06-09 |
20110136645 | Multi-Unit Blood Processor With Rotating Valves - An apparatus for separating at least two discrete volumes of a composite liquid into at least a first component and a second component, comprising a valve design that facilitates loading and unloading of blood bags and associated tubing and bag sets. The valves comprise a rotating head, mounted on a shaft, which assumes a “load” position. The head pivots to an “open” position, which secures the tube in its designated location, but which maintains an open lumen through the tube. When the head is in a “closed” position, blood components cannot flow through the tube. The valve apparatus comprises means for maintaining a constant pressure on the tube and contact with the tube as the tube is melted and sealed. | 2011-06-09 |
20110136646 | Multi-Unit Blood Processor And Bag Set with Asymmetric Manifold - An apparatus for separating at least two discrete volumes of a composite liquid into at least a first component and a second component, comprising an asymmetrical junction or manifold in the blood bag and tubing set inhibits errors when the bags and tubes are loaded into the device. | 2011-06-09 |
20110136647 | Fiber-Reinforced Swing Bucket Centrifuge Rotor And Related Methods - A centrifuge rotor is provided having a rotor core that defines a rotational axis of the rotor. A plurality of bucket supports is arranged about the axis of rotation. The rotor includes first and second straps that respectively wrap around two diametrically-opposed ones of the bucket supports for restricting outward movement of the two bucket supports relative to the rotor core. The first and second straps intersect one another at a location through the axis of rotation of the rotor. | 2011-06-09 |
20110136648 | CENTRIFUGE WITH REMOVABLE CORE FOR SCALABLE CENTRIFUGATION - A centrifuge apparatus is provided that operates at certain predetermined parameters depending upon a product to be separated and is useable with a plurality of rotor assemblies. For example, a first rotor assembly of said plurality of rotor assemblies includes a first core having a first core configuration which is contained within a rotor housing of the first rotor assembly to define a first volume capacity such that the product passing through the first rotor assembly having the first volume capacity during rotation of the first rotor assembly in the centrifuge apparatus achieves a first particle separation of the product. A second rotor assembly of said plurality of rotor assemblies includes a second core having a second core configuration which is contained with a rotor housing of the second rotor assembly to define a second volume capacity such that product passing through the second rotor assembly having the second volume capacity during rotation of the second rotor assembly in the centrifuge apparatus achieves a second particle separation of the product. It is observed that the second particle separation is a linear change with respect to the first particle separation. | 2011-06-09 |
20110136649 | SEPARATION DISC AND SEPARATOR - The invention relates to a separation disc and a milk separator comprising a rotor, which separation disc together with other separation discs forms a stack of separation discs rotatable together with the rotor. The separation disc comprises a truncated substantially conical portion and an annular flange element connected to the conical portion at the smallest radius and extends therefrom radially inwards substantially perpendicular to the axis of rotation. The flange element has a radial extent corresponding to at least 10% of the radial extent of the conical portion. The inner radial edge of the flange element includes recesses distributed along the edge and adapted to protrusions on a column connected to the rotor, extending coaxially through the separation discs. The recesses are substantially filled by the protrusions. The radial extent of the recesses corresponds to at least 20% of the radial extent of the flange element. | 2011-06-09 |
20110136650 | Multi-Unit Blood Processor With Progressively Centered Chambers - An apparatus for separating at least two discrete volumes of a composite liquid into at least a first component and a second component, comprising a well provided on a rotor near the axis of rotation for receiving a relatively rare blood component, such as mesenchymal stem cells (MSC), or for receiving a fluid that can be used multiple times, such as a washing solution. The well is placed radially outwardly from the axis of rotation and radially inwardly from cavity, which receives bags containing blood or another biologic fluid. The well is placed in a low centrifugal force region relative to the position of the cavity. | 2011-06-09 |
20110136651 | GLASS-CERAMICS AND METHOD FOR MANUFACTURING THE SAME - For providing glass-ceramics having properties suitable for use as a substrate of an information storage medium of next generation such as one for the perpendicular magnetic recording system without employing arsenic and antimony components which adversely affect human beings and the environment, there are provided glass-ceramics comprising SiO | 2011-06-09 |
20110136652 | HIGHLY REFRACTIVE AND HIGHLY TRANSPARENT OPTICAL GLASS - The optical glass has a refractive index n | 2011-06-09 |
20110136653 | METHOD FOR THE PRODUCTION OF A POROUS, CERAMIC SURFACE LAYER - A method for producing a porous ceramic surface layer on a substrate includes providing a mixture including at least one polymer and at least one ceramic material and applying the mixture to the substrate. | 2011-06-09 |
20110136654 | COMPONENT IN A COMBUSTION SYSTEM, AND PROCESS FOR PREVENTING SLAG, ASH, AND CHAR BUILDUP - Disclosed herein is a component in a combustion system comprising a composite, the composite comprising silicon carbide; and a refractory metal silicide comprising a phase selected from Rm | 2011-06-09 |
20110136655 | Process and System for the Transfer of a Metal Catalyst Component from One Particle to Another - One exemplary embodiment can be a process for facilitating a transfer of a metal catalyst component from at least one donor particle to at least one recipient particle in a catalytic naphtha reforming unit. The process can include transferring an effective amount of the metal catalyst component from the at least one donor particle to the at least one recipient particle under conditions to effect such transfer to improve a conversion of a hydrocarbon feed. | 2011-06-09 |
20110136656 | DEODORIZING CATALYST, DEODORIZING METHOD USING THE SAME, AND METHOD FOR REGENERATING THE CATALYST - A deodorizing catalyst showing high activity at room temperature, having great adsorption capacity, and possessing activity persistence capable of withstanding continued use; a deodorizing method using the catalyst; and a method for regenerating the catalyst are provided. | 2011-06-09 |
20110136657 | HIGHLY HEAT-RESISTANT BETA-TYPE ZEOLITE AND SCR CATALYST EMPLOYING THE SAME - A subject for the invention is to provide a highly heat-resistant SCR catalyst which has an NOx reduction percentage of 40% or higher at 200° C. after a hydrothermal durability treatment. The invention relates to use of β-type zeolite which has an SiO | 2011-06-09 |
20110136658 | THE CATALYST USED IN THE REACTION OF BROMINATING OXIDATION OF METHANE AND THE CATALYST USED IN THE FARTHER REACTION OF PRODUCING HIGHER HYDROCARBON - A catalyst used in the reaction of oxidative bromination of methane is provided. The catalyst is prepared by the following procedures: mixing at least one of the precursors selected from the compounds of Rh, Ru, Cu, Zn, Ag, Ce, V, W, Cd, Mo, Mn, Cr and La which can dissolve in water with the Si precursor, hydrolyzing, drying and sintering. In the catalysis system, methane reacts with HBr, H | 2011-06-09 |
20110136659 | POROUS BODY PRECURSORS, SHAPED POROUS BODIES, PROCESSES FOR MAKING THEM, AND END-USE PRODUCTS BASED UPON THE SAME - The present invention provides porous body precursors and shaped porous bodies. Also included are catalysts and other end-use products based upon the shaped porous bodies and thus the porous body precursors. Finally, processes for making these are provided. The porous body precursors, comprise one or more topography-enhancing additives, i.e., additives that are capable of at least marginally enhancing one or more of surface area, aspect ratio, pore volume, median pore diameter, surface morphology, etc. Downstream products need not necessarily comprise the topography-enhancing additives in order to exhibit the benefits of their inclusion in the porous body precursors. | 2011-06-09 |
20110136660 | PHOTOCATALYST-COATED BODY - A photocatalyst-coated body which exhibits ability to decompose harmful gases while preventing deterioration of the substrate for a long time period is provided. The photocatalyst-coated body comprises a substrate, an intermediate layer provided on the substrate and a photocatalyst layer provided on the intermediate layer. The photocatalyst layer comprises photocatalyst particles composed of metal oxide which is excited by ultraviolet light. The intermediate layer comprises a weather resistant resin and a hydroxyphenyl triazine compound. | 2011-06-09 |
20110136661 | Non-hygroscopic stabilized catalyst for the in-situ generation of sulfate free radicals - This invention relates to methods for producing, and the resulting compositions comprising non-hygroscopic stabilized catalyst for use with peroxysulfates for the in-situ generation of sulfate free radicals in recreational water. | 2011-06-09 |
20110136662 | CATALYTIC SEEDING CONTROL METHOD - A catalytic seeding control method is disclosed. A catalytic metal film is deposited on a substrate with a nonwettable inclined surface. The catalytic metal film is then melted to form metal droplets. The metal droplets roll along the nonwettable inclined surface and aggregate to form a singular catalytic seed on the bottom of the nonwettable inclined surface. Then, the location of the singular catalytic seed is precisely controlled. Also, the size of the catalytic seed is controlled by adjusting the size of the inclined surface and the thickness of the catalytic metal layer to grow a one-dimensional structure with specific localization and single well-aligned manipulated size. The structure is utilized for the integrated microelectronic device fabrication. | 2011-06-09 |
20110136663 | METHOD AND APPARATUS FOR SORBENT PRODUCTION, PRIMARILY FOR REMOVING ARSENIC FROM DRINKING WATER - The object of the invention is method and apparatus for sorbent production. The method comprises the steps of saturating a moisture-absorbent, wettable organic support material with the aqueous solution of a water-soluble ferric salt, then filtering it and drying it to constant weight; saturating the support material with a stoichiometric quantity (computed relative to the iron content of the support material) of oxalic acid and/or water-soluble salt of oxalic acid, then filtering it and drying it to constant weight, while converting the iron ions to insoluble ferric oxalate; converting the saturated support material to activated carbon by anaerobic heating, then subjecting said saturated support material to anaerobic cooling, while the ferric oxalate is decomposed into iron and carbon dioxide; preoxidizing iron particles of the activated carbon by a water-soluble peroxide compound, filtering the activated carbon, and rinsing it to completely remove salt therefrom, then filtering it again and drying it; converting the iron hydroxide formed on the surface of the iron particles into magnetite by anaerobic heating of the activated carbon, and subsequently cooling in an anaerobic manner the thus produced sorbent to room temperature. | 2011-06-09 |
20110136664 | DIPHENYLSULFONE BRIDGED COMPOUND, COLOR FORMING SUBSTANCE FOR THERMAL RECORDING AND THERMAL RECORDING MATERIAL - Diphenylsulfone bridged compounds of the general formula: (1) wherein n is an integer of 1 to 10. Further, there is disclosed a thermal recording material comprising a support and, superimposed thereon, a thermosensitive color forming layer containing a color forming substance for thermal recording consisting of any of the diphenylsulfone bridged compounds and a color forming substance consisting of a colorless or light-colored leuco dye. This thermal recording material excels in the storability, especially wet heat resistance and oil resistance, of image areas and further exhibits excellent characteristics in the storability, especially heat resistance, of undeveloped areas. | 2011-06-09 |
20110136665 | Ternary Fungicidal Mixtures - Ternary fungicidal mixtures comprising, as active components,
| 2011-06-09 |
20110136666 | CHEMICAL COMPOUNDS - The present invention relates to substituted pyrimidine derivatives as well as N-oxides and agriculturally acceptable salts thereof, and their use to control undesired plant growth, in particular in crops of useful plants. The invention extends to herbicidal compositions comprising such compounds, N-oxides and/or salts as well as mixtures of the same with one or more further active ingredient (such as, for example, an herbicide, fungicide, insecticide and/or plant growth regulator) and/or a safener. | 2011-06-09 |
20110136667 | METHOD FOR CONTROLLING UNDESIRED MIMOSOIDEAE VEGETATION - Disclosed is method for controlling undesired vegetation of subfamily Mimosoideae comprising applying to the undesired vegetation or its environment a herbicidally effective amount of a mixture comprising (a) one or more compounds selected from the compound of Formula 1 and salts, esters and thioesters thereof: | 2011-06-09 |
20110136668 | SYSTEM FOR PROTECTION OF PLANTS FROM PATHOGENS USING ALKAMIDES - System, including methods compositions, and kits, for controlling the growth of fungi and other pathogens in plants using at least one alkamide, which may function by increasing or eliciting natural defense mechanisms of the plants against such pathogens. | 2011-06-09 |
20110136669 | Continuous Fiber Layer Comprising an Active Substance on the Basis of Bio-Polymers, the use Thereof, and Method for the Production Thereof - The invention relates to continuous fiber layers comprising an active substance on the basis of bio-polymers, comprising a fibrous, bio-polymer active substance carrier, and at least one active substance associated with the carrier and releasable from the continuous fiber layer; to formulations comprising an active substance, said formulations comprising such continuous fiber layers; to the use of continuous fiber layers comprising an active substance for the production of formulations comprising an active substance; and to a method for the production of continuous fiber layers comprising an active substance. The invention further relates to corresponding continuous fiber layers comprising an active substance and to the use thereof for the production of wound treatment and hygiene products, and to the respectively produced wound treatment and hygiene products. | 2011-06-09 |
20110136670 | HIGH TEMPERATURE SUPERCONDUCTORS - Compositions are disclosed of a matrix of a high temperature superconductive oxide such as YBCO, with non-superconductive particles distributed in the matrix. The non-superconductive particles comprise at least one rare earth element (RE) and at least one of tantalum (Ta) and niobium (Nb). Of particular interest are non-superconductive particles of composition RE-Ta | 2011-06-09 |
20110136671 | DISPLACER AND SUPERCONDUCTING MAGNET - A displacer for adjusting a level of a liquid cryogen in a cryostat. The displacer including an expandable member at least partially defining a sealed chamber. The expandable member being configured to transition from a collapsed state where the sealed chamber has a smaller volume to an expanded state where the sealed chamber has a larger volume. The displacer includes a first end piece attached to a first end of the expandable member and a second end piece attached to a second end of the expandable member. | 2011-06-09 |
20110136672 | Superconductors with improved mecanical strength - A hollow tube ( | 2011-06-09 |
20110136673 | PRECURSOR WIRE OF OXIDE SUPERCONDUCTING WIRE AND PRODUCTION METHOD THEREOF AND OXIDE SUPERCONDUCTING WIRE PRODUCED BY USING THE PRECURSOR WIRE - A precursor wire of an oxide superconducting wire includes a first sheath made of silver or silver alloy, a center portion in the first sheath, and a plurality of peripheral segments placed close to one another at the inside of the first sheath so as to surround the center portion. Each of the peripheral segments is formed as a monofilamentary segment that has an arch-shaped cross section and that includes a ribbon-shaped filament made of a precursor of an oxide superconductor and covered with a second sheath made of silver or silver alloy. The multiple peripheral segments are placed in a multilayer state in the form of concentric circles such that wide-width surfaces of the peripheral segments surround the center portion. | 2011-06-09 |
20110136674 | SUPERCONDUCTING TAPE WIRE MATERIAL AND METHOD OF MANUFACTURING SAME - A method of manufacturing a superconducting tape wire, wherein a reduction in critical current in the superconducting tape wire and the effective AC loss are suppressed. To manufacture the superconducting tape wire, the filaments filled with superconducting material powder and having a flat elliptic or rectangular cross section are disposed in a pipe having a shape whose sides in a pressing direction have a smaller length than adjacent sides, and then the pipe is compressed in the short-side direction to form the pipe in a tape shape. | 2011-06-09 |
20110136675 | IDENTIFICATION AND CHARACTERIZATION OF PROTEINS USING NEW DATABASE SEARCH MODES - A method of selecting a set of candidate polypeptides for a sample polypeptide that includes a first refining of a collection of candidate polypeptides from differences in mass of fragments of the sample polypeptide produced by mass spectrometry and a second refining of the collection of candidate polypeptides from the absolute mass of the sample polypeptide and the absolute mass of the fragments. | 2011-06-09 |
20110136676 | GEOMETRIC PATTERNS AND LIPID BILAYERS FOR DNA MOLECULE ORGANIZATION AND USES THEREOF - The invention is related to nucleic acid arrays and methods of using nucleic acid arrays. | 2011-06-09 |
20110136677 | METHODS OF BEAD MANIPULATION AND FORMING BEAD ARRAYS - According to various embodiments, a method is provided that comprises washing an array of DNA-coated beads on a substrate, with a wash solution to remove stacked beads from the substrate. The wash solution can include inert solid beads in a carrier. The DNA-coated beads can have an average diameter and the solid beads in the wash solution can have an average diameter that is at least twice the diameter of the DNA-coated beads. The washing can form dislodged DNA-coated beads and a monolayer of DNA-coated beads. In some embodiments, first beads for forming an array are contacted with a poly(ethylene glycol) (PEG) solution comprising a PEG having a molecular weight of about 350 Da or less. In some embodiments, slides for forming bead arrays are provided as are systems for imaging the same. | 2011-06-09 |
20110136678 | METHODOLOGY FOR ANALYSIS OF SEQUENCE VARIATIONS WITHIN THE HCV NS3/4A GENOMIC REGION - The current invention relates to a standardized method for amplification of an HCV NS3/4A or NS3 nucleic acid fragment of any one of HCV genotypes 5 to 6 or HCV genotype 1 as a tool for analysis of sequence variations that may be correlated with 5 HCV drug resistance. | 2011-06-09 |
20110136679 | Imprinted Array - There is described a gene expression array comprising more than one imprinted gene and one or more control genes for the diagnosis of human epigenetic diseases resulting from assisted reproduction or the disruption. | 2011-06-09 |
20110136680 | TUMOR GRADING AND CANCER PROGNOSIS - The disclosure includes the identification and use of gene expression profiles, or patterns, with clinical relevance to cancer. In particular, the disclosure includes the identities of genes that are expressed in correlation with tumor grade. The levels of gene expression are disclosed as a molecular index for determining tumor grade in a patient and predicting clinical outcome, and so prognosis, for the patient. The molecular grading of cancer may optionally be used in combination with a second molecular index for diagnosing cancer and its prognosis. The disclosure further includes methods for predicting cancer recurrence, and/or predicting occurrence of metastatic cancer. For diagnosis or prognosis, the disclosure further includes methods for determining or selecting the treatment of cancer based upon the likelihood of life expectancy, cancer recurrence, and/or cancer metastasis. | 2011-06-09 |
20110136681 | SELECTION OF STEM CELL CLONES WITH DEFINED DIFFERENTIATION CAPABILITIES - Disclosed are methods for producing a clonal population of cells involving: a) obtaining a population of pluripotent or multipotent cells that have been expanded in vitro and maintained in an undifferentiated or essentially undifferentiated state; b) expanding individualized cells of the population into clonal populations of cells; and c) selecting one or more clonal population of cells determined to have the ability to differentiate into a population that is at least about 50% homogeneous for either neural cell types, hepatocytes, or cardiomyocytes. Also disclosed are clonal populations of cells produced by the methods of the present invention, and methods of treating disease in subjects involving administration of clonal cells of the present invention to a subject. Methods of screening test compounds that involve contacting a test compound with a clonal population of cells produced by the methods of the present invention are also set forth. | 2011-06-09 |
20110136682 | ANTENNARY FUCOSYLATION IN GLYCOPROTEINS FROM CHO CELLS - The present invention provides methods of evaluating CHO cells and producing recombinant glycoproteins. | 2011-06-09 |
20110136683 | Systems and Methods for Expression-Based Discrimination of Distinct Clinical Disease States in Prostate Cancer - A system for expression-based discrimination of distinct clinical disease states in prostate cancer is provided that is based on the identification of sets of gene transcripts, which are characterized in that changes in expression of each gene transcript within a set of gene transcripts can be correlated with recurrent or non-recurrent prostate cancer. The Prostate Cancer Prognostic system provides for sets of “prostate cancer prognostic” target sequences and further provides for combinations of polynucleotide probes and primers derived there from. These combinations of polynucleotide probes can be provided in solution or as an array. The combination of probes and the arrays can be used for diagnosis. The invention further provides further methods of classifying prostate cancer tissue. | 2011-06-09 |
20110136684 | CHEMICAL REACTION MONITOR - Disclosed herein are systems for monitoring chemical reactions. The systems can comprise a lighting device, a camera device for obtaining an image of the chemical reaction mixtures and an analyzer program to process data obtained from the image. Also disclosed are methods of monitoring the progress of chemical reactions using these systems. | 2011-06-09 |
20110136685 | METHOD FOR DETERMINING A PREDISPOSITION TO BASAL CELL CARCINOMA AND FOR SCREENING TREATMENTS THEREOF - The present invention relates to methods for detecting a predisposition to a basal cell carcinoma and methods for screening a treatment of a basal cell carcinoma. | 2011-06-09 |
20110136686 | SEQUENCE MATCHING ALLOWING FOR ERRORS - Systems, methods, and other embodiments associated with sequence matching with no more than a number E errors are disclosed. A test fragment to be located within a target sequence with at most a number E errors is received. The test fragment is broken into E+1 test sub-fragments. If one test sub-fragment is located within the target sequence with no errors; a determination is made as to whether the other test sub-fragments are located within the target sequence adjacent to the one test sub-fragment with a total of at most E errors. If the other test sub-fragments are located within the target sequence adjacent the one test sub-fragment with at most E errors, a location of the test fragment within the target sequence is returned. | 2011-06-09 |
20110136687 | METHOD FOR DETERMINING THE DEGREE OF METHYLATION OF DEFINED CYTOSINES IN GENOMIC DNA IN THE SEQUENCE CONTEXT OF 5'-CpG-3' - A method is described for the detection of the degree of methylation of a specific cytosine in the sequence context 5′-CpG-3′ of a genomic DNA sample. In the first step, the genomic DNA is chemically treated in such a way that the cytosine bases are converted to uracil, but not the 5-methylcytosine bases. Then segments of the genomic DNA which contain the said specific cytosine are amplified, whereby the amplified products are given a detectable label and in the following steps the extent of hybridization of the amplified products on two classes of oligonucleotides is determined by detection of the label of the amplified products, and a conclusion is made on the extent of methylation of said specific cytosine in the genomic DNA sample from the ratio of the labels detected on the two classes of oligonucleotides as a consequence of the hybridization. | 2011-06-09 |
20110136688 | RECOMBINANT BACTERIOPHAGE AND METHODS FOR THEIR USE - Modified forms of naturally occurring bacteriocins, such as the R-type pyocins of | 2011-06-09 |
20110136689 | Dual Expression Vector System for Antibody Expression in Bacterial and Mammalian Cells - The present invention provides a dual expression vector, and methods for its use, for the expression and secretion of a full-length polypeptide of interest in eukaryotic cells, and a soluble domain or fragment of the polypeptide in bacteria. When expressed in bacteria, transcription from a bacterial promoter within a first intron and termination at the stop codon in a second intron results in expression of a fragment of the polypeptide, e.g., a Fab fragment, whereas in mammalian cells, splicing removes the bacterial regulatory sequences located in the two introns and generates the mammalian signal sequence, allowing expression of the full-length polypeptide, e.g., IgG heavy or light chain polypeptide. The dual expression vector system of the invention can be used to select and screen for new monoclonal antibodies, as well as to optimize monoclonal antibodies for binding to antigenic molecules of interest. | 2011-06-09 |
20110136690 | METHODS FOR IDENTIFYING AND MONITORING DRUG SIDE EFFECTS - The present invention relates generally to methods for identifying drug side effects by detecting perturbations in organ-specific molecular blood fingerprints. The invention further relates to methods for identifying drug-specific organ-specific molecular blood fingerprints. As such, the present invention provides compositions comprising organ-specific proteins, detection reagents for detecting such proteins, and panels and arrays for determining organ-specific molecular blood fingerprints. | 2011-06-09 |
20110136691 | GOLD-SILVER ALLOY NANOPARTICLE CHIP, METHOD OF FABRICATING THE SAME AND METHOD OF DETECTING MICROORGANISMS USING THE SAME - Provided are a gold-silver alloy nanoparticle chip, a method of fabricating the same and a method of detecting microorganisms using the same. The gold-silver alloy nanoparticle chip includes a hydrophilized glass substrate, a self-assembled monolayer formed on the glass substrate, and gold-silver alloy nanoparticles fixed on the self-assembled monolayer. The gold-silver alloy nanoparticle chip having such a structure enables microorganisms in a water purifier and tap water to be readily detected and enables detection efficiency to be enhanced. | 2011-06-09 |
20110136692 | PROTEIN MICROARRAYS FOR MASS SPECTROMETRY AND METHODS OF USE THEREFOR - The present invention relates to the use of mass spectrometry to analyze arrays. The present invention provides methods for characterizing solutions comprising one or more proteins using arrays and mass spectrometry. The arrays of the present invention are coated with porous gold and utilize hydrophobic and hydrophilic self-assembled monolayers. | 2011-06-09 |
20110136693 | ELECTRICALLY ACTIVE COMBINATORIAL CHEMICAL (EACC) CHIP FOR BIOCHEMICAL ANALYTE DETECTION - Apparatus and methods are disclosed for electrically active combinatorial-chemical (EACC) chips for biochemical analyte detection. An apparatus includes a substrate that has an array of regions defining multiple cells, wherein each of the cells includes a reaction cavity that contains multiple functional binding groups. A method of detecting an analyte providing the reaction cavity between a source and a drain or a pair of electrodes, applying a voltage and monitoring a parameter indicative of an analyte characteristic. A process of fabricating an EACC include bonding an analyte to the multiple functional binding groups of each reaction cavity, and forming an analyte sensing structure including the substrate. | 2011-06-09 |
20110136694 | DENSITY MODIFICATION IN ARRAYS OF SURFACE-ATTACHED NUCLEIC ACID MOLECULES - Substrates having nucleic acid polymers attached at varying surface densities and methods for creating substrates having nucleic acid polymers attached at varying surface densities are provided. Methods according to embodiments of the invention are adapted to the rapid synthesis of arrays of DNA polymers on a substrate surface. In embodiments of the invention an array of DNA molecules on a substrate comprises a plurality of DNA polymers attached to a trifunctional linker such that at least two DNA polymers are attached to one trifunctional linker that is attached to the surface of the substrate. By coupling trifunctional linkers to trifunctional linkers that are attached to a substrate surface, the density of DNA polymers on a substrate surface is increased. | 2011-06-09 |
20110136695 | UNIVERSAL LIBRARIES FOR IMMUNOGLOBULIN - Libraries of immunoglobulins of interest are described, the libraries containing mutated immunoglobulins of interest in which a single predetermined amino acid has been substituted in one or more positions in one or more complementarity-determining regions of the immunoglobulin of interest. The libraries comprise a series of subset libraries, in which the predetermined amino acid is “walked through” each of the six complementarity-determining regions (CDRs) of the immunoglobulin of interest not only individually but also for each of the possible combinatorial variations of the CDRs, resulting in subset libraries that include mutated immunoglobulins having the predetermined amino acid at one or more positions in each CDR, and collectively having the predetermined amino acid at each position in each CDR. The invention is further drawn to universal libraries containing one such library for each naturally-occurring amino acid as the single predetermined amino acid, totaling twenty libraries; and also to libraries of nucleic acids encoding the described libraries. | 2011-06-09 |
20110136696 | CONTINUOUS POLYMER SYNTHESIZER - Described is a system and method for synthesizing polymeric molecules such as oligonucleotides and polypeptides. The system is capable of continuously synthesizing molecules by providing an array of reaction sites and an array of stations for carrying out synthetic manipulations. The reaction sites in the former array can be placed in a fixed order and at fixed intervals relative to each other. Similarly, the stations can be placed in a fixed order and at fixed intervals relative to each other. The two arrays can be moved relative to each other such that the stations carry out desired steps of a reaction scheme at each reaction site. The relative locations of the stations and the schedule for the relative movement can correlate with the order and duration of reaction steps in the reaction scheme such that once a reaction site has completed a cycle of interacting with the full array of stations then the reaction scheme is complete. | 2011-06-09 |