23rd week of 2018 patent applcation highlights part 37 |
Patent application number | Title | Published |
20180156704 | Geotechnical Apparatus - A geotechnical apparatus comprising a holder with a coiled rod with a probe, such as a penetrometer, a rod bending/straightening device and a drive unit for both uncoiling the coiled continuous rod and pushing the uncoiled rod with the probe into the ground and for pulling such a rod with the probe out of the ground and recoiling the continuous rod, wherein the drive unit comprises two grippers to alternatingly grip the rod and move it along its longitudinal axis over a predefined length, the bending/straightening device has a first set of rollers, at least two of which are at one side of the rod and the remaining rollers are at an opposing side of the rod, such that the rollers convert the coiled rod to an essentially straight rod when uncoiling and convert the straight rod to a coiled rod of essentially constant coil diameter when coiling. | 2018-06-07 |
20180156705 | ACCESS PORT FOR A THERMOGRAVIMETRIC ANALYZER FURNACE - The analyzer of the present invention is specifically adapted to provide moisture determinations for foods and other agricultural material. It allows the operator to introduce a precise weight of sample into a crucible in a closed furnace in a controlled environment through an access port in the furnace cover. The access port in the cover can be tapered to allow easy access to an underlying aligned crucible and allow an operator to add and remove sample material from the crucible until a precise desired sample weight is reached as measured by a balance within the furnace. The access port is enclosed by an insulated cover after the samples are sequentially placed in the crucibles. | 2018-06-07 |
20180156706 | APPARATUS FOR ANALYSING THE PARTICULATE MATTER CONTENT OF AN AEROSOL - An apparatus for analysing the particulate matter content of an aerosol includes an aerosol chamber configured to receive an aerosol, the particulate matter content of which should be analysed, at least one ultrasonic generator configured to produce ultrasonic waves in the aerosol received in the aerosol chamber, an ultrasonic detector configured to detect ultrasonic waves produced by the at least one ultrasonic generator in the aerosol, and an evaluator having a data exchange communication link with the ultrasonic detector and configured to ascertain the matter content on the basis of signals output by the ultrasonic detector. The ultrasonic generator and the ultrasonic detector are positioned relative to one another such that a path length to be traversed by ultrasonic waves between the ultrasonic generator and the ultrasonic detector is less than 1 cm. | 2018-06-07 |
20180156707 | PORTABLE HYDROSTATIC TESTER - The present disclosure provides a portable hydrostatic tester for hydrostatic pressure resistance of a fabric without the need for a power source and the need for cutting the fabric before testing. In some embodiments, the hydrostatic tester comprises (1) a supporting structure comprising a test opening; (2) a connection tube connected to the test opening; (3) a liquid column connected to the connection tube; and (4) a reservoir configured to contain a liquid that is connected to one or both of the liquid column and the connection tube. In some embodiments, the reservoir is configured such that the liquid is forced by gravity through the test opening via the connection tube at a hydrostatic pressure dependent upon the elevation of the reservoir. The present disclosure also provides a method of testing the hydrostatic pressure resistance of a fabric using the hydrostatic tester described above. | 2018-06-07 |
20180156708 | FLUIDIC DEVICE THAT EMULATES A FRACTURE IN A FORMATION AND IS USED TO TEST FLOW OF A TREATMENT FLUID THROUGH THE DEVICE - A fluidic device that can emulate a fracture is provided and includes a body with a first region that can emulate a propped fracture and a second region that can emulate an earth formation material. A test fluid flows into the device at a test pressure and temperature, and substantially fills the first and second regions. A portion of the test fluid flows back out of the device when the pressure is reduced. A method of emulating fluid flow through a fracture is provided, the method including a fluidic device that includes a body, a first region that emulates the fracture, and a second region that emulates an earth formation material. Flowing a test fluid at a test pressure and temperature into the first region, and reducing a pressure of the test fluid, thereby allowing some of the test fluid to flow from the device. | 2018-06-07 |
20180156709 | CHIP-TYPE PARTICULATE MATTER SENSOR - A chip-type PM (Particulate Matter) sensor comprising a sensing unit installed in a cylindrical housing mounted on an exhaust pipe, the sensing unit having a sensing pattern for sensing particulate matters contained in exhaust gas, wherein the sensing unit may include a substrate formed in a direction perpendicular to the longitudinal direction of the housing, and the sensing pattern formed on a surface of the substrate, facing the exhaust pipe, and configured to sense the particulate matters. | 2018-06-07 |
20180156710 | FLOW CYTOMETERY SYSTEM WITH FLUIDICS CONTROL SYSTEM - A system, method, and apparatus are provided for flow cytometry. In one example, the flow cytometry system includes dual laser devices and dual scatter channels to measure velocity of particles in a core stream of sample fluid. The total flow rate of the sample fluid and the sheath fluid around the sample fluid is controlled, and thus held constant, by a feedback control system controlling a vacuum pump based on differential pressure across ends of a flow channel in the flow cell. | 2018-06-07 |
20180156711 | FLOW CYTOMETERY SYSTEM WITH STEPPER FLOW CONTROL VALVE - A system, method, and apparatus are provided for flow cytometry. In one example, the flow cytometry system includes dual laser devices and dual scatter channels to measure velocity of particles in a core stream of sample fluid. The total flow rate of the sample fluid and the sheath fluid around the sample fluid is controlled, and thus held constant, by a feedback control system controlling a vacuum pump based on differential pressure across ends of a flow channel in the flow cell. A stepper flow control valves are disclosed that apply a physical fluid resistance to a flow of sheath fluid in the flow cytometer. The physical fluid resistance regulates a flow rate of the sheath fluid and thereby regulates a flow rate of sample fluid in the flow cytometer. | 2018-06-07 |
20180156712 | TIMING AND/OR PHASE ADJUSTMENT OF THE SEPARATION AND/OR CHARGING OF DROPS FROM A FLUID STREAM IN A FLOW CYTOMETER - Disclosed is a system for setting the timing or phase of the separation of droplets from a fluid stream in a flow cytometer, or the timing or phase of a charge pulse generator, based upon the collected charge of charged droplets. In one embodiment, a conductive mesh can be used to collect the charged droplets that are either deflected or not deflected by the deflection plates. In another embodiment, the charge can be collected from metal plates in the waste collection device. In addition, a defanning device is disclosed that allows substantially uniform deflection of charged cells. | 2018-06-07 |
20180156713 | Automated Slide Assessments and Tracking in Digital Microscopy - The present disclosure provides methods for automated slide assessments made in conjunction with digital image-based microscopy. Automated methods of acquiring patient information and specimen information from prepared slides, and digitally linking such information into patient-tagged specimen data, are provided. Also provided are methods that include automatically identifying an optimal area for morphological assessment of a blood smear on a hematological slide, including methods for triggering the analysis of such an area, e.g., using an automated digital image-based hematology system. The present disclosure also provides devices, systems and computer readable media for use in performing processes of the herein described methods. | 2018-06-07 |
20180156714 | HANDRAIL FRICTION CHECKING DEVICE - A handrail friction checking device comprises a handrail gripper for gripping the handrail and movable together with the handrail, a spring with one end of the spring being fixed and the other end being connected to the handrail gripper so that the spring can apply a spring force which is opposed to the direction of handrail movement to the handrail gripper when the handrail gripper moves along with the handrail and a sensor which is disposed in a way that it is distanced from the handrail gripper and can be triggered by the handrail gripper when the handrail gripper moves along with the handrail. | 2018-06-07 |
20180156715 | HOLLOW FIBRE WAVEGUIDE GAS CELLS - This disclosure relates to hollow fibre waveguide spectroscopic gas cells built using connectors and the method for making them. The connectors are used to construct gas cell end pieces which allow gas and light to enter the hollow fibre waveguide simultaneously thus creating a gas cell. The connectors comprise a window which intersects or is in close proximity to a junction of bores within the connector, the bores transmitting gas through the connector to or from the hollow fibre waveguide. Connectors may also be used to connect two sections of fibre together in order to produce longer gas cells which enhance the signal-to-noise ratio of spectroscopic measurements. The window, which is at least partially transparent at the wavelength of the light used for spectroscopic purposes, is affixed so as to maintain a gas tight seal for the gas cell. These gas cells provide a combination of long path length and low volume and are well suited to mid-infrared spectroscopic applications which require a fast response time or low flow rate. | 2018-06-07 |
20180156716 | Absorption Spectrum Detection of a Fluid - The present disclosure describes a device for measuring an optical absorption property of a fluid as function of wavelength. The device comprises a broadband light source for emitting light, a plurality of integrated optical waveguides for guiding this light and a light coupler for coupling the emitted light into the integrated optical waveguides such that the light coupled into each integrated optical waveguide has substantially the same spectral distribution. The device also comprises a microfluidic channel for containing the fluid, arranged such as to allow an interaction of the light propagating through each waveguide with the fluid in the microfluidic channel, and a plurality of spectral analysis devices optically coupled to corresponding waveguides—such as to receive the light after interaction with the fluid. The spectral analysis devices are adapted for generating a signal representative of a plurality of spectral components of the light. | 2018-06-07 |
20180156717 | MULTI-TEST ASSAY SYSTEMS AND METHODS OF USING THE SAME - Embodiments disclosed herein are directed to multi-test assay systems for analyzing biological material and methods of using such multi-test assay systems. For example, the multi-test assay system can detect or identify one or more biological markers representative of or corresponding to an illness or disease. | 2018-06-07 |
20180156718 | LINEAR ABSORPTION SPECTROMETER TO OPTICALLY DETERMINE AN ABSOLUTE MOLE FRACTION OF RADIOCARBON IN A SAMPLE - A linear absorption spectrometer includes: a laser light source that provides mid-infrared laser light; a high finesse optical resonator that includes: a sample cell operating at a temperature from 220 K to 300 K during linear absorption of mid-infrared laser light by radiocarbon and including: a linear absorption optical path length greater than a kilometer; a first zero-pressure difference mirror mount on which a first supermirror is disposed; a second zero-pressure difference mirror mount on which a second supermirror is disposed; an optical switch interposed between the laser light source and the high finesse optical resonator that modulates and communicates mid-infrared laser light to the high finesse optical resonator; a photoreceiver that receives cavity ring down light and includes a noise equivalent power that is less than a shot noise limit of cavity ring down light. | 2018-06-07 |
20180156719 | METHOD FOR ADJUSTING A MEASURING DEVICE - The present application relates to a method for adjusting a measuring device for measuring a measurand of a medium using at least one measuring sensor, including: laboratory calibration of the measuring device in a calibration solution, laboratory calibration of the measuring device in air, determination of a correction factor for correcting the laboratory calibration value of the measuring device in air to the laboratory calibration value of the measuring device in the calibration solution, on-site calibration of the measuring device in air, using the correction factor to correct the on-site calibration value of the measuring device in air, and on-site adjustment of the measuring device using the corrected on-site calibration value. | 2018-06-07 |
20180156720 | INCORPORATION OF INTEGRATED COMPUTATIONAL ELEMENTS WITHIN OPTICAL ANALYSIS TOOLS HAVING A MINIATURIZED OPERATIONAL PROFILE - Conventional optical analysis tools containing an integrated computational element may have an operational profile that is too large for convenient use within confined locales. Optical analysis tools having a miniaturized operational profile can comprise: an electromagnetic radiation source that provides electromagnetic radiation to an optical train; and an optical computing device positioned within the optical train. The optical computing device comprises a planar array detector having at least two optical detection regions. At least one of the at least two optical detection regions has an integrated computational element disposed thereon. The planar array detector and the integrated computational element are in a fixed configuration with respect to one another. | 2018-06-07 |
20180156721 | PORTABLE CORTISOL SENSING PLATFORM BASED ON COMPACT UV LIGHT SOURCES - Systems and methods for detecting a biological analyte are provided. The biological analyte can be, for example, cortisol. Detection can be achieved without external labels/mediators. Microfluidic systems can be incorporated into the optical sensor for enhanced point-of-care applications. The sensor can be used in a variety of low-power electronics for wearable applications. | 2018-06-07 |
20180156722 | DARK-ENVIRONMENT SIMULTANEOUS CULTURING-OBSERVING APPARATUS - A dark-environment simultaneous culturing-observing apparatus includes: an observation-subject holding unit for holding an observation subject; a dark-environment culturing chamber for culturing, in a dark environment, bacteria in the observation subject held by the observation-subject holding unit; an infrared light source for irradiating, with infrared light, the observation subject held by the observation-subject holding unit kept in the dark-environment culturing chamber; and an infrared light camera for photographing the observation subject irradiated with infrared light from the infrared light source. | 2018-06-07 |
20180156723 | SPECTROMETER WITH A RELAY LIGHTPIPE - A lightpipe is coupled to a spectrometer based on a laterally variable optical filter. The lightpipe may be used for both guiding the illuminating light towards a sample and collecting light reflected or emitted by the sample upon illumination, for spectral measurements at a distance from the sample afforded by the lightpipe. The lightpipe may include a slab of homogeneous transparent material for unconstrained bidirectional propagation of light in bulk of the material. The lightpipe may be solid, hollow, or sectioned for separated guiding of the illuminating and the reflected light. | 2018-06-07 |
20180156724 | A METHOD AND A SYSTEM FOR DETERMINING A COMPOSITION OF A GAS MIX IN A VEHICLE - The invention relates to a method, system, and computer program product for determining a composition of a gas mix in a vehicle, said method comprising the steps of: exposing the gas mix with light; measuring data relating to a light absorption of the gas mix at at least two different pressures of the gas mix; and determining the composition of the gas mix based on said measured data. The invention relates also to a vehicle equipped with said system. | 2018-06-07 |
20180156725 | DEVICE AND METHOD FOR DETERMINING THE DIRT LOAD IN A RINSING OR DETERGENT SOLUTION - A device for determining a dirt load in a rinsing or detergent solution in a water-conducting household appliance includes a sensor configured to execute a near-infrared spectroscopy for acquiring a spectral measured value of a dirt component in the rinsing or detergent solution in the water-conducting household appliance. A determination unit determines the dirt load of the rinsing or detergent solution on the basis of the acquired spectral measured value of the dirt component in the rinsing or detergent solution, and an adjustment unit adjusts a wash parameter of a current wash program in response to the determined dirt load. | 2018-06-07 |
20180156726 | OPTICAL ABSORBANCE MEASUREMENTS WITH SELF-CALIBRATION AND EXTENDED DYNAMIC RANGE - Detector data representative of an intensity of light that impinges on a detector after being emitted from a light source and passing through a gas over a path length can be analyzed using a first analysis method to obtain a first calculation of an analyte concentration in the volume of gas and a second analysis method to obtain a second calculation of the analyte concentration. The second calculation can be promoted as the analyte concentration upon determining that the analyte concentration is out of a first target range for the first analysis method. | 2018-06-07 |
20180156727 | ADVANCED IN-SITU PARTICLE DETECTION SYSTEM FOR SEMICONDUCTOR SUBSTRATE PROCESSING SYSTEMS - An FI having an in-situ particle detector and a method for particle detection therein are provided. In one aspect, the FI includes a fan, a substrate support, a particle detector, and an exhaust outlet. The fan, substrate support, and particle detector are arranged such that, in operation, the fan directs air towards the exhaust outlet and over a substrate on the substrate support to create laminar flow. The particle detector, positioned downstream from the substrate support and upstream from the exhaust outlet, analyzes the air and detects particle concentration before the particles are exhausted. The collected particle detection data may be combined with data from other sensors in the FI and used to identify the source of particle contamination. The particle detector may also be incorporated into other system components, including but not limited to, a load-lock or buffer chamber to detect particle concentration therein. | 2018-06-07 |
20180156728 | CHARACTERIZATION OF MULTILAYER STRUCTURES - A method for determining characteristics of a layer-based structure comprises repetitively irradiating the layer-based structure with a transient continuous wave electromagnetic radiation and capturing as a function of time a transient part of the reflection or transmission of the transient continuous wave electromagnetic radiation reflected at or transmitted through the different interfaces of layer-based structure. The method furthermore comprises deriving from the transient part of the reflected or transmitted transient continuous wave electromagnetic radiation as function of time information regarding different contributions in the transient part of the reflected or transmitted transient continuous wave electromagnetic radiation stemming from the reflections at different interfaces of the layer-based structure and determining from said information at least geometric information and/or electromagnetic properties of the different layers of the layer based structure. A corresponding system employs features of the method. | 2018-06-07 |
20180156729 | METHOD FOR DETERMINING A MEASURED QUANTITY CORRELATED WITH AN EXTINCTION, AND CORRESPONDING SENSOR ARRANGEMENT - A method is disclosed for determining a measured quantity, correlated with an extinction, in a medium, including the steps: radiation of light into the medium and measurement of the extinction after a first path length; radiation of light into the medium and measurement of the extinction after a second path length, wherein the first path length differs from the second path length; and determination of the measured quantity correlated with the extinction using the extinction after first path length and extinction after second path length. Additionally disclosed is a sensor arrangement for execution of the method. | 2018-06-07 |
20180156730 | DUAL FUNCTION FLUOROMETER-ABSORBANCE SENSOR - A dual function fluorometer-absorbance sensor features an absorbance-based sensor configured to receive one part of an optical signal transmitted through a body of water of interest along an optical beam transmission path, and determine absorbance-based sensor signaling containing information about an absorbance of the optical signal by one or more absorbance species of interest present in the body of water; and a fluorescence-based sensor configured to receive another part of the optical signal transmitted through the body of water of interest along a corresponding optical beam transmission path that is perpendicular to the optical beam transmission path, and determine fluorescence-based sensor signaling containing information about a fluorescence transmitted by one or more fluorophore species of interest present in the body of water. | 2018-06-07 |
20180156731 | WIDE-ANGLE EMISSION FILTER, OPTICAL SENSOR ASSEMBLY HAVING THE SAME, PCR SYSTEM HAVING THE SAME, AND METHOD OF MANUFACTURING THE SAME - The wide-angle emission filter includes a base matrix, a photoresist, and a colorant. The base matrix has a flat shape and including a transparent material. The base matrix does not generate fluorescent light or phosphorescent light by an excitation light. The photoresist is disposed in the base matrix. The photoresist is fixed in a solid state through at least one method selected from the group consisting of thermal hardening, photo hardening, and drying. The colorant is disposed in the base matrix and includes light having a predetermined wavelength range. The wide-angle emission filter filters the excitation light regardless of an incident angle of the excitation light. | 2018-06-07 |
20180156732 | MULTIPLE REACTION PARALLEL MEASUREMENT APPARATUS AND METHOD FOR THE SAME - A multiple reaction parallel measurement apparatus is intended to measure a large number of reactions quickly, simply and with high accuracy. The apparatus includes: a plurality of light guiding paths corresponding to a plurality of reaction spot array elements, including a measuring end able to be in proximity of or in contact with each one of the reaction spots, and arranged to guide light generated by a reaction at the reaction spot to a connecting end; a measurement head arranged such that the measuring ends reach all together predetermined measurement positions of the corresponding reaction spots of the reaction spot array elements at a predetermined scan period; a light guiding path selector including a light guiding region optically connected to the connecting end; a light receiving unit; and a digital data converter to obtain digital data by converting image region data obtained from the light receiving unit. | 2018-06-07 |
20180156733 | SAMPLE TEST CARDS - The present invention is directed to sample test cards having an increased sample well capacity for analyzing biological or other test samples. In one embodiment, the sample test cards of the present invention comprises a fluid channel network disposed in both the first surface and the second surface and connecting the fluid intake port to the sample wells, the fluid channel network comprising at least one distribution channels, a plurality of fill channels operatively connected to the at least one distribution channel, a plurality of through-channels operatively connected to one or more of the fill channels and a plurality of horizontally orientated fill ports operatively connecting the fill channels to the sample wells. In another embodiment, the sample test cards may comprise a fluid channel network comprising a first distribution channel disposed on a first surface, the first distribution channel comprising a fluid flow path from an fluid intake port to a plurality of second distribution channels or diffusion channels, wherein the second distribution channel or diffusion channels further comprise a plurality of diffusion barriers or “islands” operable to interrupt fluid flow between opposing sample wells, and wherein the second distribution channels or diffusion channels are operatively connected to the sample wells by a plurality of fill channels. The test card of this invention may comprise from 80 to 140 individual sample wells, for example, in a test card sample test cards of the present invention have a generally rectangular shape sample test card having dimensions of from about 90 to about 95 mm in width, from about 55 to about 60 mm in height and from about 4 to about 5 mm in thickness. | 2018-06-07 |
20180156734 | MULTI-TEST ASSAY SYSTEMS AND METHODS OF USING THE SAME - Embodiments disclosed herein are directed to multi-test assay systems for analyzing biological material and methods of using such multi-test assay systems. For example, the multi-test assay system can detect or identify one or more biological markers representative of or corresponding to an illness or disease. | 2018-06-07 |
20180156735 | COLOUR MEASUREMENT OF GEMSTONES - The present disclosure relates to an apparatus for measuring a colour parameter of a gemstone. The apparatus comprises a support structure for supporting the gemstone at a measurement location, an illumination system for illuminating the gemstone at the measurement location, an imaging device directed towards the measurement location for obtaining an image of the gemstone, and an image processor for analysing the image of the gemstone. The image processor is configured to identify a set of stone pixels corresponding to the gemstone in the image and identify luminance and chrominance values for each stone pixel. A colour vector is calculated from an expression of the chrominance values of the stone pixels in chrominance space, the colour vector extending in chrominance space from stone pixels having a relatively high luminance value to stone pixels having a relatively low luminance value. This colour vector is used in the determination of the colour parameter. | 2018-06-07 |
20180156736 | DETECTION APPARATUS AND DETECTION METHOD - A detection apparatus improves abnormality detection accuracy after start of an inspection operation while reducing the amount of work that is done before the start of the operation. The apparatus includes an object characteristic storage device that stores a parameter indicating a characteristic of an abnormal object, an object detection unit that detects an abnormal object candidate from image information by using the parameter, an object storage unit that stores the abnormal object candidate, an object display unit that displays the abnormal object candidate stored in the object storage unit, a calibration input unit that receives input of calibration information on the abnormal object candidate, and, based on the calibration information, corrects the abnormal object candidate stored in the object storage unit, and an object characteristic calibration unit that calibrates the parameter stored in the object characteristic storage device, based on the calibration information received by the calibration input unit. | 2018-06-07 |
20180156737 | SYSTEM AND METHOD FOR THE VIDEO INSPECTION OF A PANTOGRAPH ALONG AN OVERHEAD CONTACT LINE - Method for the video inspection of a pantograph ( | 2018-06-07 |
20180156738 | APPARATUS AND METHOD FOR THE OPTICAL DETECTION OF INNER WALLS - An apparatus for the optical detection of inner walls includes at least one camera, an optical imaging arrangement, and an illumination arrangement. The apparatus is configured to record in a panoramic view by means of the camera a plurality of regions of an inner wall which are axially offset from one another. The apparatus is distinguished by virtue of the illumination arrangement having at least two different functional states, wherein a first brightness distribution emitted by the illumination arrangement is assigned to a first functional state, the brightness distribution differing from a second brightness distribution in at least one second functional state. | 2018-06-07 |
20180156739 | SUBSTRATE INSPECTION METHOD, COMPUTER STORAGE MEDIUM AND SUBSTRATE INSPECTION APPARATUS - A method of inspecting a substrate to be repeatedly treated along a predetermined transfer way in a plurality of kinds of different treatment apparatuses, includes: imaging a substrate that has been treated in one of the treatment apparatuses, to acquire a first substrate image; imaging a substrate that has been an object for imaging the first substrate image and further treated in another treatment apparatus different from the one treatment apparatus after treated in the one treatment apparatus, to acquire a second substrate image; then performing defect inspection, based on the first substrate image and the second substrate image; and identifying, depending on whether or not a defect detected from the second substrate image is not detected from the first substrate image, whether or not the defect is caused by a treatment after the first substrate image is acquired and a treatment before the second substrate image is acquired. | 2018-06-07 |
20180156740 | IDENTIFYING DEFECTS IN TRANSPARENT CONTAINERS - Described herein are various technologies related to inspecting transparent containers for both opaque and transparent defects. An emitter is configured to direct a color gradient through a sidewall of a transparent container, such that color of light that passes through the sidewall varies across the sidewall. A camera is configured to capture an image of the sidewall of the transparent container while the color gradient passes through the sidewall of the container. A computing system receives the image and determines whether the sidewall of the container includes either an opaque or a transparent defect based upon the image. | 2018-06-07 |
20180156741 | INSPECTION DEVICES AND INSPECTION METHODS - Inspection devices and inspection methods are disclosed. The inspection method includes: performing X-ray scanning on an object being inspected so as to generate an image of the object being inspected; dividing the image of the object being inspected to determine at least one region of interest; detecting interaction between a cosmic ray and the region of interest to obtain a detection value; calculating a scattering characteristic value and/or an absorption characteristic value of the cosmic ray in the region of interest based on size information of the region of interest and the detection value; and discriminating a material attribute of the region of interest by means of the scattering characteristic value and/or the absorption characteristic value. With the above technical solutions, inspection accuracy and inspection efficiency may be improved. | 2018-06-07 |
20180156742 | X-Ray Imaging with a Detector Capable of Resolving Photon Energy - The present teaching relates to methods, systems, and apparatus for X-ray imaging with a detector capable of resolving photon energy. In one example, an X-ray microscope is disclosed. The X-ray microscope comprises an X-ray source and a detector. The X-ray source is configured for irradiating X-ray to a sample. The detector is configured for: detecting X-ray photons from the irradiated X-ray, determining energy of each of the detected X-ray photons, and generating an image of the sample based on detected X-ray photons that have energies in a predetermined range. | 2018-06-07 |
20180156743 | SYSTEMS AND METHODS FOR RADIOGRAPHIC INSPECTION - An inspection method include introducing a mixture of expanding foam and a particulate material into a region of interest of an object, fixing the powder within the region of the interest relative to the object, and acquiring image data of the object and particulate mixture using an x-ray source and an x-ray detector. The particulate has a density that is greater than the density of a material forming the object to provide contrast between the region of interest and the object in an image generated using the image data. | 2018-06-07 |
20180156744 | NANO-LEVEL EVALUATION OF KEROGEN-RICH RESERVOIR ROCK - Examples of nano-level evaluation of kerogen-rich reservoir rock are described. A micro-scale beam is formed from kerogen-rich reservoir rock. The beam has reservoir rock and kerogen, which has polymeric properties. A maximum dimension of the micro-scale beam is at most 1000 micrometers. A mechanical experiment that includes a tension test or a compression test is performed on the micro-scale beam. The mechanical experiment is imaged using a scanning electron microscope (SEM). A material parameter of the kerogen in the micro-scale beam is determined based on results of the mechanical experiment and images obtained responsive to the imaging. The material parameter includes a behavior of the kerogen in response to the mechanical experiment. The behavior of the kerogen can be used to determine, among other things, the energy required to break kerogen in a kerogen-rich shale to improve hydraulic fracturing efficiency. | 2018-06-07 |
20180156745 | Conical Collimator for X-ray Measurements - X ray apparatus includes a sample stage ( | 2018-06-07 |
20180156746 | SYSTEMS AND METHODS FOR SINGLE-MOLECULE DETECTION USING NANOTUBES - A method for single-molecule detection is provided and uses a carbon nanotube having a probe entity attached thereto to define a first state of the carbon nanotube. The carbon nanotube is introduced to a target entity to define a second state of the carbon nanotube. The electrical conductance of the carbon nanotube in the first and second states is compared to detect the presence of a biomolecular entity. A system for single-molecule detection including a carbon nanotube is also provided. | 2018-06-07 |
20180156747 | GAS SENSORS - The present disclosure is directed to a gas sensor that includes an active sensor area that is exposed to an environment for detection of elements. The gas sensor may be an air quality sensor that can be fixed in position or carried by a user. The gas sensor includes a heater formed above chamber. The gas sensor includes an active sensor layer above the heater that forms the active sensor area. The gas sensor can include a passive conductive layer, such as a hotplate that further conducts and distributes heat from the heater to the active sensor area. The heater can include a plurality of extensions. The heater can also include a first conductive layer and a second conductive layer on the first conductive layer where the second conductive layer includes a plurality of openings to increase an amount of heat and to more evenly distribute heat from the heater to the active sensor area. | 2018-06-07 |
20180156748 | PORTABLE DEVICE FOR MEASURING DIELECTRIC AND/OR MAGNETIC CHARACTERISTICS OF SAMPLES - A portable device includes first and second connectors capable of guiding an electromagnetic wave, a sample carrier installed between the first premier and second connectors and including a cavity housing a sample, an electronic module including an electromagnetic wave generator, and a processing system capable of analysing the electromagnetic wave exiting the second connector in order to deliver a first dielectric permittivity measurement and/or a second magnetic permeability measurement, a computer device including a control system capable of controlling the operation of the electronic module and of recovering each first or second measurement, and a portable container housing the first and second connectors, the sample carrier, the electronic module and the computer device. | 2018-06-07 |
20180156749 | COMPUTER IMPLEMENTED METHOD FOR DETERMINING INTRINSIC PARAMETER IN A STACKED NANOWIRES MOSFET - Embodiments of the invention determine intrinsic parameters of stacked nanowires/nanosheets GAA MOSFETs comprising N | 2018-06-07 |
20180156750 | ACCURATE ANALYTE MEASUREMENTS FOR ELECTROCHEMICAL TEST STRIP BASED ON SENSED PHYSICAL CHARACTERISTIC(S) OF THE SAMPLE CONTAINING THE ANALYTE - Various embodiments for methods and systems that allow for a more accurate analyte concentration with a biosensor by determining at least one physical characteristic of the sample containing the analyte and deriving one of a batch slope, sampling time, or combinations thereof to attain accurate glucose concentration. | 2018-06-07 |
20180156751 | CO2 CONCENTRATION MEASUREMENT IN DRY GAS MIXTURES - Described herein is an apparatus and methods for characterizing a fluid composition including exposing electrolyte to one fluid mixture, collecting a signal from an electrode in contact with the electrolyte, and simultaneously exposing the electrolyte to a second fluid, collecting a signal from a second electrode in contact with the electrolyte exposed to the second fluid, and comparing the signal difference between the electrodes with the Nerst equation wherein the temperature of the electrolyte is above 488° C. Carbon dioxide, nitrogen, and/or oxygen may be present in the fluid and/or the second fluid. | 2018-06-07 |
20180156752 | System and Method for Small Molecule Detection - A system for analyzing a content of a sample material is presented. The system includes a fiber sensitized to a first substance, and at least one electrode configured to expose the fiber to an electric field. The system includes an optical sensor configured to detect a displacement of the fiber when the fiber is exposed to the electric field, and a processor configured to use the displacement of the fiber to characterize a content of the sample material. | 2018-06-07 |
20180156753 | Method and Apparatus for Flaw Inspection of Friction-Weld Part of Stem in Engine Valve - Provided is a method for flaw inspection of a stem joint of a valve including: an internal flaw inspection step including causing a flaw detection probe to be disposed so as to face upward in water in a tank in an ultrasonic inspection chamber, holding a valve in such fashion as to cause the tip to face the flaw detection probe, and inspecting for a flaw at the interior of the stem joint; and a surface flaw inspection step including causing a flaw detection probe to be disposed horizontally in an eddy-current inspection chamber, holding a valve in such fashion as to cause the side face of a stem of the valve to be close to and facing the flaw detection probe, inspecting for a flaw on the surface of the stem joint while the flaw detection probe and the valve are made to engage in mutual rotation. The valves are transferred from a valve loading position to the ultrasonic inspection chamber, from the ultrasonic inspection chamber to the eddy-current inspection chamber, and from the eddy-current inspection chamber to a valve unloading position in substantially simultaneous, continuous, synchronous, and/or coordinated fashion. | 2018-06-07 |
20180156754 | ANALYTE SENSOR AND ANALYTE SENSING METHOD - There are provided an analyte sensor and an analyte sensing method which provide measurements in a wide phase range, a reduction in size, and lowering of current consumption. That is, in an analyte sensor and an analyte sensing method, a detection element ( | 2018-06-07 |
20180156755 | APPARATUS FOR BIOMATERIAL AND METHOD OF DETECTING BIOMATERIAL - Provided is an apparatus for detecting biomaterial and method of detecting biomaterial. The method include providing a sample including a fluorescent material and a biomaterial on one surface of an ultrasound receiving unit, and measuring an ultrasonic wave generated by the fluorescent material by emitting light to the sample. | 2018-06-07 |
20180156756 | SYSTEMS AND METHODS FOR MONITORING BLISTER PACK COMPLIANCE - Disclosed herein is a system for determining discontinuities in a blister pack. The system includes a blister pack and a discontinuity sensing apparatus coupled to the blister pack. The blister pack includes a tray with a plurality of cells and a seal layer arranged to seal the cells. The discontinuity sensing apparatus includes a signal generation element and a signal receiving element. In one embodiment, the signal generation element is arranged to transmit an acoustic pulse. In another embodiment, the signal generation element is arranged to transmit a swept acoustic signal. In one embodiment, the discontinuity sensing apparatus is coupled to the blister pack such that each of the plurality of cells is positioned at a unique distance from the discontinuity sensing apparatus. The determinations on discontinuities can be made in part from information from the time domain and/or in part from information from the frequency domain. | 2018-06-07 |
20180156757 | VIBRATION MONITORING SYSTEM AND METHOD - A method detects the presence of a vehicle on a railway track using a sensing processor monitoring a sensing system for detecting vibration into ground installed along the railway track. The sensing system includes a detection module for detecting a vehicle on the railway track. The method includes an initialization step which includes the sub-steps of emitting a first signal to be received by the sensing processor through the sensing system, sending a first message to the sensing processor, monitoring the sensing system, and configuring the detection module in function of the received first signal and configuration data received in the first message. The configuration data can include location of the initialization device, intensity/magnitude of the first signal, emission time of the first signal, and/or type of object corresponding to the first signal. | 2018-06-07 |
20180156758 | MAGNETOSTRICTIVE COLD SPRAY COATING FOR ENHANCED ULTRASONIC INSPECTION - An improved process for performing ultrasonic sensing and inspections wherein a cold-spray technique is used to kinetically bond powdered material to a substrate and then an EMAT sensor is magnetically attached to the coating. In use the ultrasound will transfer from the magnetostrictive layer into the substrate more effectively than any glued coating without concerns for long term degradation. | 2018-06-07 |
20180156759 | METHOD FOR ANALYZING CEMENT INTEGRITY IN CASED WELLS USING SONIC LOGGING - Methods are provided for identifying a cementation status of a multi-string cased wellbore utilizing sonic tools with monopole and/or dipole transmitters and with an array of sonic receivers axially displaced from the transmitter(s). The sonic tool is used to record waveforms. The waveforms are then processed to generate slowness and/or attenuation dispersions. The slowness and/or attenuation dispersions are projected onto a slowness and/or attenuation axis, and the results are compared to a data set of projected slowness and/or attenuation dispersions representing a plurality of different multi-string cased wellbore cement status scenarios in order to select the scenario most closely associated with the results. The presence or lack of eccentering of a casing is similarly obtained where the data set includes projected dispersions representing properly centered and ec-centered casings. | 2018-06-07 |
20180156760 | INDUCTIVE FLASH DESORBER - An inductive flash desorber includes: an induction coil that includes a coil; an substrate disposed through the induction coil; and a flow tube interposed between the induction coil and the substrate such that the flow tube: is encircled by the coil; surrounds the substrate within the coil; receives a carrier fluid that entrains the desorbed analyte from the substrate; and forms an analytical composition comprising the carrier fluid and the desorbed analyte, the flow tube including: a first end that receives the carrier fluid; and a second end opposing the first end through which the analytical composition flows. | 2018-06-07 |
20180156761 | AUTOMATIC ANALYSIS DEVICE - An automatic analysis device capable of effectively preventing incorrect container number input when analysis conditions are set. An image display area and text display area are provided in a setting screen. An image in which a selection area is assigned to each container number corresponding to a sample container is displayed in the image display area. If a selection area in the image display area is selected through operation unit operation, the container number expressing the selected selection area is displayed in the text display area (container number input part). If the container number expressing the selected sample container is displayed in the text display area (container number input part) as a result of operation unit operation, the display mode of the selection area corresponding to the container number is switched. | 2018-06-07 |
20180156762 | ANALYTICAL DEVICE FOR CONSTITUENTS OF A SAMPLE - An analytical device for determining a measured variable dependent on the concentration of one or more constituents of a sample includes a decomposition reactor surrounded by an insulating tube, a heating apparatus, an oxygen production system including at least one oxygen permeable membrane, a housing, and a feed gas guiding system for supplying a feed gas to the at least one membrane of the oxygen production system. The feed gas guiding system includes a reaction space surrounding the at least one membrane and is connected with an inflow duct open to the environment such that at least two partitions are arranged coaxially within the insulating tube and surrounding the decomposition reactor, where the partitions subdivide an intermediate space arranged between the decomposition reactor and the insulating tube into annular chambers forming the feed gas guiding system, where the annular chambers are connected with one another by overflow openings. | 2018-06-07 |
20180156763 | COMPOSITIONS, APPARATUS, AND METHODS FOR DETERMINING HARDNESS OF WATER AND MAGNESIUM ION IN AN ANALYTE COMPOSITION - Compositions, kits, and methods of using the kits and compositions to determine the hardness of and/or magnesium concentration in a solution are described. The kit can include a lyophilized composition that has an absorbance at a detectable wavelength in response to the hardness of the solution and or the concentration of magnesium in the solution. | 2018-06-07 |
20180156764 | LIQUID CRYSTAL COMPOSITION, AND PH SENSING DEVICE USING THE SAME - A liquid crystal composition includes a nematic liquid crystal, and a compound of Formula (I) where R is an alkyl, aryl, aralkyl or heteroaryl having 6 to 30 carbon atoms, wherein the compound accounts for 0.3 to 0.6% of the liquid crystal composition. | 2018-06-07 |
20180156765 | SENSOR FOR DETERMINING A MEASURAND DEPENDENT UPON A CONCENTRATION OF REACTIVE OXYGEN SPECIES - The present application discloses a sensor for determining a measurand correlated with a concentration of at least one analyte belonging to the class of reactive oxygen species in a measuring fluid, the sensor including a sensor element having an indicator substance, wherein the indicator substance is oxidized into an oxidized form of the indicator substance by the at least one analyte, a means for generating a flow of current in the sensor element that causes a reduction of the oxidized form of the indicator substance and thereby regeneration of the indicator substance, an optical measuring sensor to detect measuring radiation influenced by the oxidized form of the indicator substance and to generate an electrical measuring signal using the influenced measuring radiation, and a sensor switch connected to the optical measuring sensor to receive the measuring signal and to ascertain a measured value of the measurand using the measuring signal. | 2018-06-07 |
20180156766 | Networked Environmental Monitoring System and Method - A system and method for monitoring environment employ a dense network of low-cost sensor nodes. The method includes obtaining environmental information by combining a plurality of observations; wherein the plurality of observations are made with in-situ or remote sensors; wherein the sensors are of different degrees of accuracy in a way to complement each other, and of different cost, and wherein the low-cost sensors form a high-density network comprising a plurality of distributed sensors. The system can monitor gas concentrations over urban areas, industrial, forest, farm, wetland, power plants and other types of surfaces. | 2018-06-07 |
20180156767 | CONTINUAL CROP DEVELOPMENT PROFILING USING DYNAMICAL EXTENDED RANGE WEATHER FORECASTING WITH ROUTINE REMOTELY-SENSED VALIDATION IMAGERY - A modeling framework for estimating crop growth and development over the course of an entire growing season generates a continuing profile of crop development from any point prior to and during a growing season until a crop maturity date is reached. The modeling framework applies extended range weather forecasts and remotely-sensed imagery to improve crop growth and development estimation, validation and projection. Output from the profile of crop development profile generates a combination of data for use in auxiliary farm management applications. | 2018-06-07 |
20180156768 | PAPERLESS RECORDING PASTEURIZATION CONTROL SYSTEM - A pasteurization system including a flow sensor connected to a pasteurization tube to determine a flow rate of the food substance, a temperature sensor connected to the pasteurization tube to determine a temperature of the food substance, and a processor. The processor receives the flow rate from the flow sensor, receives the temperature from the temperature sensor, selects either a flow rate threshold from a plurality of flow rate thresholds based on the temperature received from the temperature sensor, each flow rate threshold associated with a respective temperature or a temperature threshold from a plurality of temperature thresholds based on the flow rate received from the flow sensor, each temperature threshold associated with a respective flow rate, and compares the selected flow rate threshold or the temperature threshold to the respective flow fate or the respective temperature, and determines a position of a valve based on the comparison. | 2018-06-07 |
20180156769 | SYSTEMS AND METHODS FOR MONITORING AND MANAGING SOLUTION SAMPLES - Disclosed are various embodiments of a monitoring apparatus and a method for obtaining solution sample measurements. The monitoring apparatus may include a hollow body and a top cover to seal the hollow body to provide a waterproof monitoring apparatus. Other embodiments may also include a weighted bottom portion beneath the hollow body and a sensor exposed to the environment to monitor and acquire data from a solution sample. | 2018-06-07 |
20180156770 | SYSTEM FOR MONITORING CROPS AND SOIL CONDITIONS - According to an aspect, a system for monitoring crops and soil conditions below a crop canopy includes a retractable boom assembly adapted to be coupled to an unmanned aerial vehicle. Further according to this aspect, the boom assembly includes an actuator and an elongate probe is coupled to the retractable boom assembly. Still further, the system includes a controller for maneuvering the elongate probe below the crop canopy while the boom assembly is extended by the actuator. | 2018-06-07 |
20180156771 | Fuel Compatibility and Stability Analyzer - Fuel sampling systems are disclosed. In one embodiment, a fuel sampling system includes an optical capture device and an analysis computing device that stores logic for implementing an evaluation sequence. During the evaluation sequence, the analysis computing device performs at least the following: receive a captured image from the optical capture device, identify areas of highest contrast in the captured image, and determine if the areas of highest contrast define a ring. If the areas of highest contrast define a ring, evaluate a contrast ratio between the ring and areas outside of the ring, and determine if the captured image reflects a fuel sample that exceeds a predetermined limit of propensity for settling. If so, indicate that the captured image reflects a fuel sample that is not acceptable. Otherwise, indicate that the captured image reflects a fuel sample that is acceptable. | 2018-06-07 |
20180156772 | Fuel Oil Stability - A method for predicting the critical solvent power of a visbroken residue stream of interest, CSP | 2018-06-07 |
20180156773 | METHOD FOR IMAGING BIOLOGIC FLUID SAMPLES USING A PREDETERMINED DISTRIBUTION - A method for analyzing a biologic fluid sample includes the steps of: a) providing a spatially mapped chamber; b) providing a predetermined repeatable non-uniform spatial distribution of one or more constituents within the sample, which distribution indicates the presence or absence of a statistically significant number of constituents within the sample in each chamber sub-region; c) selecting one or more image techniques for each sub-region based on the presence or absence of the statistically significant number of one or more constituents in that sub-region as indicated by the distribution; d) creating image data representative of the biologic fluid sample in each sub-region, using the one or more image techniques selected for that sub-region; and e) analyzing the sample. | 2018-06-07 |
20180156774 | KIT FOR DIAGNOSIS OF CORONARY HEART DISEASE USING MULTI-METABOLITES AND CLINICAL PARAMETERS, AND METHOD FOR DIAGNOSIS OF CORONARY HEART DISEASE USING THE SAME - The present disclosure relates to a method and a diagnostic kit for diagnosing stable angina and acute myocardial infarction early through simple blood testing and checking of clinical parameters. Unlike conventional diagnostic methods, stable angina can be diagnosed as distinguished from acute myocardial infarction according to the present disclosure by using one diagnostic platform based on the change in the in-vivo levels of biological metabolites having different metabolic pathways and clinical parameters as well as medications affecting the onset and progress of the disease through multivariable analysis. | 2018-06-07 |
20180156775 | DEVICE AND SYSTEM FOR COLLECTING AND ANALYZING VAPOR CONDENSATE, PARTICULARLY EXHALED BREATH CONDENSATE, AS WELL AS METHOD OF USING THE SAME - The present invention is related to the field of bio/chemical sensing, assays and applications. Particularly, the present invention is related to collecting a small amount of a vapor condensate sample (e.g. the exhaled breath condensate (EBC) from a subject of a volume as small as 10 fL (femto-Liter) in a single drop), preventing or significantly reducing an evaporation of the collected vapor condensate sample, analyzing the sample, analyzing the sample by mobile-phone, and performing such collection and analysis by a person without any professionals. | 2018-06-07 |
20180156776 | METHOD OF DETECTION OF OCCULT PANCREATIC BETA CELL DYSFUNCTION IN NORMOGLYCEMIC PATIENTS - This invention relates to a method for detecting the presence of or likelihood of a patient of developing occult pancreatic beta cell dysfunction, and a method for detecting the presence of or likelihood of a patient of developing clinically significant post-prandial hyperglycemia. The methods involve (a) measuring a level of alpha-hydroxybutyrate (AHB) in a single fasting baseline biological sample of the patient; (b) comparing the level of AHB in the single fasting baseline biological sample to a reference AHB level; and (c) determining the presence of or likelihood of developing the disorder in the patient based on the comparison in step (b). An increased AHB level at fasting baseline indicates that a normoglycemic, normo-insulinemic and/or non-dyslipidemic patient has developed or has an increased likelihood of developing occult pancreatic beta cell dysfunction. An increased AHB level at fasting baseline and an elevated glucose level of at least about 155 mg/dL at 30 minutes and/or 1 hour indicates that a normoglycemic, normo-insulinemic and/or non-dyslipidemic patient has developed or has an increased likelihood of developing clinically significant post-prandial hyperglycemia. | 2018-06-07 |
20180156777 | METHOD AND APPARATUS FOR HIGH-RESOLUTION IMAGING OF CELL-CELL COMMUNICATION - A vertical cell pairing (VCP) system comprising: a substrate having a top surface; at least one micropit formed in the top surface of the substrate, the at least one micropit being sized to seat a cell; and at least one microtrap positioned adjacent the top surface of the substrate, the at least one microtrap comprising a body having a vertical slot, wherein the vertical slot has an opening and an exit, the vertical slot being sized to pass fluid therethrough but to prevent a cell from passing therethrough; wherein the at least one microtrap is disposed relative to the at least one micropit so that a cell seated in the at least one micropit is in cell-cell communication with a cell disposed at the opening of the vertical slot. | 2018-06-07 |
20180156778 | AUTOANTIGENS FOR DIAGNOSIS OF RHEUMATOID ARTHRITIS - Disclosed herein are methods of diagnosing Rheumatoid arthritis in a subject comprising determining whether the subject is immunologically reactive with N-acetylglucosamine-6-sulfatase and/or filamin-A, wherein immunological reactivity of the subject to one or more of N-acetylglucosamine-6-sulfatase or filamin-A, as compared to an appropriate control, indicates the subject has rheumatoid arthritis. Examples of specific assays and kits for use with the methods are also disclosed. | 2018-06-07 |
20180156779 | OPTICAL CYTOMETRY - The present invention provides optical systems and methods for determining a characteristic of a cell, such as cell type, cellular response to a biochemical event, biological state and the like. The methods typically involve using interferometry to observe membrane properties in a cell and then use this information to determine one or more characteristics of a cell. The methods of the invention are useful for applications such as drug screening as well as diagnostic techniques. | 2018-06-07 |
20180156780 | COMPOSITIONS AND METHODS FOR MODULATING ONCOGENIC MIRNA - Provided herein are compositions and methods related to modulation of progenitor microRNAs (pro-miRNAs), such as for the treatment of cancer. | 2018-06-07 |
20180156781 | MODELS, METHODS AND COMPOSITIONS FOR TREATING INFLAMMATORY BOWEL DISEASE - The invention provides models of various conditions including but not limited to intestinal inflammation and/or fibrosis, inflammatory bowel disease, colitis, acute colitis, and chronic colitis, and methods of using such models for designing, screening and developing therapeutics for those conditions. The invention also provides methods, compositions, and kits for treating those conditions. | 2018-06-07 |
20180156782 | Methods for Treatment with Bucindolol Based on Genetic Targeting - The present invention concerns the use of methods for evaluating bucindolol treatment for a patient, particularly one with heart failure. It concerns methods for determining whether to administer or prescribe bucindolol to a patient based on whether the patient is homozygous for the Arg 389 polymorphism in the β1-adrenergic receptor (AR). | 2018-06-07 |
20180156783 | SYSTEM AND METHODS FOR DETECTING RIBOSOME INHIBITION - This disclosure describes a cell genetically modified to detect ribosome inhibition in the cell and methods involving such a cell. Generally, the genetically-modified cell includes an aminoglycoside-sensitive orthogonal 16S rRNA (O-16S) coding region bearing a mutated anti-Shine-Dalgarno (O-ASD) sequence, a repressor/operator system, and a polynucleotide encoding a detectable reporter under transcriptional control of the repressor/operator system. The repressor/operator system includes a coding region that encodes a transcriptional regulator and having an orthogonal SD (O-SD) sequence complementary to the 16S rRNA O-ASD sequence. The operator sequence, which is repressable by the transcriptional regulator, is operably linked to the polynucleotide encoding a detectable reporter. | 2018-06-07 |
20180156784 | IMMUNE PROFILING AND MINIMAL RESIDUE DISEASE FOLLOWING STEM CELL TRANSPLANATION IN MULTIPLE MYELOMA - The present invention provides methods for determining the level or status of minimal residue disease (MRD) in a multiple myeloma (MM) patient including analyzing peripheral NK, NK-T and T cell distribution and/or activation, and quantifying inflammatory cytokines, chemokines and growth factors in a biological sample obtained from an MM patient to provide a peripheral immune profile; and obtaining a level or status of MRD in the MM patient from the peripheral immune profile, wherein if the peripheral immune profile exceeds a pre-determined threshold, the MM patient is positive for MRD. | 2018-06-07 |
20180156785 | BIOMARKERS FOR DETERMINING THE CLINICAL RESPONSE TO CELL THERAPY - The invention relates to a method for predicting the clinical response to a therapy based on the administration of mesenchymal stem cells (MSCs) in a patient suffering from an immune-mediated inflammatory disease. The invention also relates to methods of personalised medicine as well as to therapeutic uses of MSCs in a patient suffering from an immune-mediated inflammatory disease. | 2018-06-07 |
20180156786 | BLOOD TEST METHOD - A blood test method includes providing a blood sample containing an anticoagulant containing an ethylenediaminetetraacetic acid (EDTA) salt other than a sodium, potassium, or calcium salt of EDTA, and then measuring a blood count and an electrolyte in the provided blood sample. | 2018-06-07 |
20180156787 | Multiplexed Analyses of Test Samples - The present disclosure describes methods, devices, reagents, and kits for the detection of one or more target molecules that may be present in a test sample. In one embodiment, a test sample is contacted with an aptamer that includes a tag and has a specific affinity for a target molecule. An aptamer affinity complex that includes an aptamer bound to its target molecule is allowed to form. If the test sample contains the target molecule, an aptamer affinity complex will generally form in the test sample. The aptamer affinity complex is optionally converted to an aptamer covalent complex that includes an aptamer covalently bound to its target molecule. The aptamer affinity complex (or optional aptamer covalent complex) can then be detected and/or quantified using any of a variety of methods known to one skilled in the art, including using a solid support, using mass spectrometry, and using quantitative polymerase chain reaction (Q-PCR). | 2018-06-07 |
20180156788 | Sensor Device | 2018-06-07 |
20180156789 | METHOD FOR ENHANCEMENT OF THE UNIFORM REACTION ON THE POROUS MATERIALS - The present invention provides a method for enhancement of the uniform reaction on the porous materials. Comparing with the conventional Western blotting method, the present invention is successfully demonstrated capability on increasing the immune-detection signal intensity and only needs one order of magnitude less of the processing time by applying two orders of magnitude less dosage usage-amount compared to those operated in the conventional method. | 2018-06-07 |
20180156790 | SIGNAL AMPLIFICATION IN LATERAL FLOW AND RELATED IMMUNOASSAYS - The present invention provides methods, devices, compositions (e.g., capture complexes), and kits useful for enhancing the detection of antibodies in a test sample. The methods, devices, and compositions utilize detectable Fc-binding molecules such as Protein A, Protein G, and/or an Fc-specific antibody to amplify the signal of a detected antibody in immunoassays, such as lateral flow assays. | 2018-06-07 |
20180156791 | CALIBRATING ASSAYS USING REACTION TIME - A method for performing an assay on a liquid sample for the detection of one or more analytes of interest in an assay device having a flow path which includes a sample zone and detection zone thereon includes: dispensing the sample onto the sample zone; combining the sample and a reagent, wherein the sample and reagent may be combined prior to addition of the sample to the sample zone or on the assay device, flowing the combined sample/reagent by capillary action into and through the detection zone having capture elements bound thereto, wherein a signal at least partially representative of the presence or concentration of analyte(s) is produced and detected; determining a reaction time or reaction volume; and determining the concentration of the analyte by using both the detected signal and the reaction time or reaction volume. | 2018-06-07 |
20180156792 | SAMPLING PORTION FOR A TEST DEVICE - A test device is disclosed for determining the presence or absence of a biological entity in a biological sample from a human or animal body, the test device comprising a sampling portion, the sampling portion comprising absorbent material forming a liquid flow path having a series of bends. The flow path provides a circuitous route for fluid such as buffer solution to flow within the sampling portion, improving combining of fluid with a sample received by the sampling portion. | 2018-06-07 |
20180156793 | DIAGNOSIS OF CHRONIC FATIGUE DISEASES USING DETECTION ANTIBODIES DIRECTED AGAINST A β-ADRENERGIC RECEPTOR - The application relates to a method for diagnosis of a chronic fatigue disease, e.g. CFS or CRF, comprising the step of determining the presence or absence of antibodies directed against β-adrenergic receptor in a sample of the subject to be diagnosed, wherein the presence of antibodies directed against β-adrenergic receptor is indicative of the chronic fatigue disease in said subject. Furthermore, the application relates to kits comprising β-adrenergic receptor or an antigenic peptide thereof and the use of β-adrenergic receptor or an antigenic peptide thereof for the diagnosis of a chronic fatigue disease. | 2018-06-07 |
20180156794 | Filtering Of Protein Molecular Marker DKK-3 Related To Muscle Atrophy, And Application Thereof - Disclosed are a protein molecular marker Dkk-3 protein associated with age-related muscle atrophy and the use thereof in the diagnosis of age-related muscle atrophy. The expression level of the Dkk-3 protein in amyotrophic cells is significantly higher than that in normal myocytes or tissues, and thus the Dkk-3 protein can be used as an effective marker for the detection of age-related muscle atrophy. | 2018-06-07 |
20180156795 | SENSITIVE AND RAPID METHOD FOR DETECTION OF LOW LEVELS OF LAL-REACTIVE SUBSTANCES - Methods and systems for measuring the concentration of LAL-reactive substances in fluid samples is provided. They include contacting an aqueous sample with a detection reagent to form a prepared sample. A physical property of the prepared sample may be measured to obtain at least one sample measurement characteristic of the prepared sample. Curve fitting may then be used to forecast a concentration of the LAL-reactive substance the aqueous sample will have at a specified time in the future based on the sample measurement and a correlation developed between at least one standard measurement of a physical quality of a solution with a known concentration of a LAL-reactive substance therein. The quality of the sample measurement may be validated using historical data and/or the standard measurement. | 2018-06-07 |
20180156796 | Methods of Detection of Antibiotic-Resistant Bacteria - The invention relates to novel methods of diagnosis of the presence of antibiotic-resistant bacteria in a liquid or solid sample, detection of antibiotic-resistant bacterial infections in humans or animals, and the use of antibodies or other specific binding molecules capable of binding to products of reactions carried out by bacterial enzymes which confer antibiotic resistance upon bacteria. | 2018-06-07 |
20180156797 | OPTIMIZING DIAGNOSTICS FOR GALACTOFURANOSE CONTAINING ANTIGENS - Disclosed herein are methods of detecting microbial infection in mammalian subjects comprising treatment of a sample and detection of galactofuranose (galF)-containing antigenic components utilizing monoclonal antibodies. The methods disclosed provide for pretreatment of biological samples, such as urine samples, to maximize detection of galF antigens and improvement of sensitivity of galF antigen detection assays. The methods include minimizing intelectin-1 binding to galF antigens and improvement of monoclonal antibody binding. The detection methods are useful for identifying the presence of microbial antigens related to bacterial, fungal, and parasitic pathogens, including | 2018-06-07 |
20180156798 | PROTEIN-PROTEIN INTERACTION AS BIOMARKERS - The subject invention pertains to materials and methods for the classification of cancers as sensitive or resistant to treatments based on protein-protein interactions, treatment of cancer, identification of biomarkers, identification of protein-protein interaction modulators, and selection of cancer treatments. | 2018-06-07 |
20180156799 | REAGENTS FOR HCV ANTIGEN-ANTIBODY COMBINATION ASSAYS - The present invention is directed to combination immunoassays, reagents and kits for simultaneous detection of HCV antigens and anti-HCV antibodies in a sample. The combination immunoassays of the present invention employ a non-ionic detergent that effectively exposes or releases the HCV core antigen from virions in a sample without interfering with the performance of other reagents such as the capture of anti-HCV antibodies by recombinant HCV antigens. | 2018-06-07 |
20180156800 | SCREENING METHODS FOR TARGETS FOR CANCER THERAPY - In vitro and in vive methods for screening for targets for cancer therapy are provided herein. Methods contemplate screening for targets that contribute to the immunosuppressive environment for the tumor cells, especially those targets that are associated with radiation treatment. Thus, methods provided herein are useful for identifying potential targets useful for providing cancer therapeutic agents that can be used either alone or in combination with radiation therapy. | 2018-06-07 |
20180156801 | USE OF CIRCULATING TUMOR CELL MITOTIC INDEX IN CANCER STRATIFICATION AND DIAGNOSTICS - Circulating tumor cells (CTCs) are associated with metastasis of malignant solid tumors in a patient. Presented here is evidence that CTCs exhibit cell cycle phase variability and that there is a strong correlation between the number of CTCs in a mitotic cell cycle phase and the prospects for long term survival of the subject from which the cells were obtained. Also presented herein are methods of determining the mitotic cell cycle phase of CTCs from a patient having cancer and using the information in grading malignant solid tumors and predicting the likelihood of survival of the patient. | 2018-06-07 |
20180156802 | METHODS OF TREATING LUNG CANCER BY ADMINISTRATION OF AN ALK INHIBITOR - Novel gene deletions and translocations involving chromosome 2 resulting in fusion proteins combining part of Anaplastic Lymphoma Kinase (ALK) kinase with part of a secondary protein have now been identified in human solid tumors, e.g. non-small cell lung carcinoma (NSCLC). Secondary proteins include Echinoderm Microtubule-Associated Protein-Like 4 (EML-4) and TRK-Fusion Gene (TFG). The EML4-ALK fusion protein, which retains ALK tyrosine kinase activity, was confirmed to drive the proliferation and survival of NSCLC characterized by this mutation. The invention therefore provides, in part, isolated polynucleotides and vectors encoding the disclosed mutant polypeptides, probes for detecting it, isolated mutant polypeptides, and reagents for detecting the fusion and truncated polypeptides. The invention also provides methods for determining the presence of these mutant polypeptides in a biological sample, methods for screening for compounds that inhibit the proteins, and methods for inhibiting the progression of a cancer characterized by the mutant polynucleotides or polypeptides. | 2018-06-07 |
20180156803 | P53 BIOMARKERS - The present invention relates to the identification of p53 biomarker profiles that predict response in patients with hyperproliferative disease such as cancer to a therapy, and their use in methods of treating such patients with an anti-hyperproliferative disease gene therapy. | 2018-06-07 |