23rd week of 2018 patent applcation highlights part 26 |
Patent application number | Title | Published |
20180155603 | COMPOSITIONS AND METHODS FOR FIBER-CONTAINING GROUT - The invention relates to cementitious or grout compositions and drilling fluids including reinforcement fibers and methods relating thereto. The cementitious or grout compositions include dry blend material and reinforcement fibers. Each of the fibers can have one or more of a pre-selected mean length, denier, diameter and aspect ratio to improve dispersion in dry blending the cementitious or grout compositions. | 2018-06-07 |
20180155604 | ORGANOPHILIC CLAYS AND DRILLING FLUIDS CONTAINING THEM - The organophilic clay comprises a smectite-type clay ion exchanged with quaternary ammonium ions, where at least 75 mol-% of said quaternary ammonium ions are bis-(2-hydroxypropyl)-dimethylammonium fatty acid esters and at least 90% of the fatty acid moieties of the bis-(2-hydroxypropyl)-dimethylammonium fatty acid esters have a structure RC(O) with group R being a linear alkyl or alkenyl group containing from 9 to 21 carbon atoms. The organophilic clay is useful for thickening oil based compositions, in particular drilling fluids for drilling oil or gas wells, comprising an oil phase. | 2018-06-07 |
20180155605 | SWELLABLE GLASS PARTICLES FOR REDUCING FLUID FLOW IN SUBTERRANEAN FORMATIONS - Methods, compositions, and systems that use swellable glass particles to reduce fluid flow in subterranean formations are included. An example method may comprise introducing swellable glass particles into a zone of a subterranean formation; contacting the swellable glass particles with a resin composition in the zone; and allowing the resin composition to harden in the zone whereby flow through the zone is reduced. | 2018-06-07 |
20180155606 | METHODS AND COMPOSITIONS FOR USING TEMPORARY COMPACTED MATERIALS AS WELL SERVICING FLUIDS IN A SUBTERRANEAN FORMATION - Provided is a method of treating a subterranean formation comprising: preparing a well servicing fluid comprised of a base fluid, a temporary compacted material wherein the temporary compacted material is a compacted organic acid; placing the well servicing fluid into a subterranean formation; and allowing the temporary compacted material to gradually dissolve. | 2018-06-07 |
20180155607 | HYDRATE INHIBITORS AND METHODS OF USE - Compositions and methods of using of such compositions to, for example, inhibit of the formation of gas hydrate agglomerates are provided. In one embodiment, the methods comprise: introducing hydrate inhibitor composition comprising a compound into a fluid, wherein the compound comprises a hydrophobic cation moiety, one or more lipophilic tails, and a linking moiety. | 2018-06-07 |
20180155608 | DOUBLE-HEADED HYDRATE INHIBITORS AND METHODS OF USE - Compositions and methods of using of such compositions to, for example, inhibit of the formation of gas hydrate agglomerates are provided. In one embodiment, the methods comprise: introducing a hydrate inhibitor composition comprising a compound into a fluid, wherein the compound comprises two hydrophobic cation moieties, a lipophilic tail, and two linking moieties. | 2018-06-07 |
20180155609 | THIOL-FORMYL HEMIACETAL CORROSION INHIBITORS - The present invention generally relates to compositions and methods for inhibiting corrosion at a surface in the production, transportation, storage, and separation of crude oil and natural gas. | 2018-06-07 |
20180155610 | Microemulsions and Uses Thereof to Displace Oil in Heterogeneous Porous Media - Novel microemulsion formulations comprising a surfactant or combination of surfactants are disclosed for improved crude oil cleanup or recovery from subsurface geological formations, especially those containing carbonate cements. | 2018-06-07 |
20180155611 | Stabilization of Petroleum Surfactants For Enhancing Oil Recovery - The present technology relates to compositions and related methods for stabilizing surfactants capable of increasing liquid hydrocarbon production from subterranean reservoirs. In some embodiments, the technology relates to the stabilization of sulfonate based surfactants for enhanced oil recovery (“EOR”) operations. In certain embodiments, the sulfonate based surfactants are characterized by increased thermal and chemical stability under crude oil recovery conditions. | 2018-06-07 |
20180155612 | TREATMENT FLUIDS COMPRISING WEAKLY EMULSIFYING SURFACTANTS AND ASSOCIATED METHODS - Provided are acidic treatment fluids comprising a weakly emulsifying surfactant, an aqueous base fluid, and an acid. In some embodiments, the treatment fluids are capable of forming short-lived oil-in-acid emulsions due, at least in part, to the interaction of at least a portion of the weakly emulsifying surfactant with one or more oil or gas molecules within a subterranean formation. | 2018-06-07 |
20180155613 | Stimulation of Wells in Nano-Darcy Shale Formations - This disclosure describes formulations and methods for stimulating the production from wells in nano-darcy shale formations. In one embodiment, the method includes injecting a treatment mixture containing a metal complexing agent into a nano-darcy shale formation adjacent to a well at a pressure below the fracture pressure of the formation. A sufficient contact time is allowed and then the treatment mixture is pumped from the subsurface. This has been shown to stimulate well production in shale formations. Without being held to a particular theory it appears that the metal complexing agent is binding with naturally occurring metals in the shale formation, and particularly divalent metal ions, which are then extracted with the spent fluid. This removal of naturally occurring metals may be increasing the permeability of the formation in the contact region adjacent to the well, thereby causing the observed increased production. | 2018-06-07 |
20180155614 | SELF-SUSPENDING PROPPANTS - A self-suspending proppant comprises a proppant substrate particle and a water-swellable composite coating on the proppant substrate particle comprising the combination of at least two of an anionic hydrogel polymer, a cationic hydrogel polymer and a nonionic hydrogel polymer. | 2018-06-07 |
20180155615 | Enhanced Proppant Transport for Hydraulic Fracturing - A dry composition of dry polyacrylamide and dry guar; or a liquid suspension made from the dry composition for treating subterranean formations and methods for enhancing proppant transport in fracturing fluids using the composition. | 2018-06-07 |
20180155616 | ESTERS CONTAINING NON-AROMATIC CYCLES AS SOLVENTS FOR OLED FORMULATIONS - The present invention relates to formulations for the preparation of organic electronic devices (OLEDs) which comprise at least one specific ester solvent containing a non aromatic cycle and at least one organic functional material selected from organic conductors, organic semiconductors, organic fluorescent compounds, organic phosphorescent compounds, organic light-absorbent compounds, organic light-sensitive compounds, organic photosensitisation agents and other organic photoactive compounds, selected from organometallic complexes of transition metals, rare earths, lanthanides and actinides. | 2018-06-07 |
20180155617 | AROMATIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME - Provided are an aromatic compound enhancing emission efficiency of blue light emitting region and an organic electroluminescence device including the same. The aromatic compound according to an embodiment of the inventive concept is represented by Formula 1, and more details about the constituents are provided in the disclosure. | 2018-06-07 |
20180155618 | PROCESS FOR IMPROVED HALIDE MATERIALS - Synthesizing a color stable Mn | 2018-06-07 |
20180155619 | METHOD OF PRODUCING THIOGALLATE-BASED FLUORESCENT MATERIAL, METHOD OF PRODUCING LIGHT-EMITTING DEVICE, THIOGALLATE-BASED FLUORESCENT MATERIAL AND LIGHT-EMITTING DEVICE - Provided are a method of producing a thiogallate-based fluorescent material, a method of producing a light-emitting device, a thiogallate-based fluorescent material, and a light-emitting device. The method of producing a thiogallate-based fluorescent material includes preparing a first solution containing at least one M1 ion selected from the group consisting of Sr, Be, Mg, Ca, Ba and Zn, and at least one M2 ion selected from the group consisting of Eu and Ce, and a second solution containing a sulfite ion, simultaneously supplying the first solution and the second solution to a reactor to obtain a powder containing a sulfite that contains an element M1 and an element M2, mixing a raw material that contains the powder containing the sulfite that contains the element M1 and the element M2 and a powder containing a gallium compound, with lithium chloride to obtain a mixture, and heat-treating the mixture to obtain a thiogallate-based fluorescent material. | 2018-06-07 |
20180155620 | TERNARY METAL HALIDE SCINTILLATORS - Metal halide scintillators are described. More particularly, the scintillators include Tl and/or In-based ternary metal halides, such as those of the formulas A | 2018-06-07 |
20180155621 | PHOSPHORS AND PHOSPHOR-CONVERTED LEDS - The present invention relates to pyrosilicate phosphors, to a process for the preparation thereof and to the use thereof as conversion phosphors. The present invention also relates to an emission-converting material comprising the conversion phosphor according to the invention, and to the use thereof in light sources, in particular pc-LEDs (phosphor converted light emitting devices). The present invention furthermore relates to light sources, in particular pc-LEDs, and to lighting units which comprise a primary light source and the emission-converting material according to the invention. | 2018-06-07 |
20180155622 | LIGHTING DEVICES WITH PRESCRIBED COLOUR EMISSION - Optical conversion layers based on semiconductor nanoparticles for use in lighting devices, and lighting devices including same. In various embodiments, spherical core/shell seeded nanoparticles (SNPs) or nanorod seeded nanoparticles (RSNPs) are used to form conversion layers with superior combinations of high optical density (OD), low re-absorbance and small FRET. In some embodiments, the SNPs or RSNPs form conversion layers without a host matrix. In some embodiments, the SNPs or RSNPs are embedded in a host matrix such as polymers or silicone. The conversion layers can be made extremely thin, while exhibiting the superior combinations of optical properties. Lighting devices including SNP or RSNP-based conversion layers exhibit energetically efficient superior prescribed colour emission | 2018-06-07 |
20180155623 | HIGHLY LUMINESCENT NANOSTRUCTURES AND METHODS OF PRODUCING SAME - Highly luminescent nanostructures, particularly highly luminescent quantum dots, are provided. The nanostructures have high photoluminescence quantum yields and in certain embodiments emit light at particular wavelengths and have a narrow size distribution. The nanostructures can comprise ligands, including C5-C8 carboxylic acid ligands employed during shell formation and/or dicarboxylic or polycarboxylic acid ligands provided after synthesis. Processes for producing such highly luminescent nanostructures are also provided, including methods for enriching nanostructure cores with indium and techniques for shell synthesis. | 2018-06-07 |
20180155624 | LIGHT-SPLITTING MATERIAL AND PREPARATION METHOD THEREOF, GRATING AND APPLICATION METHOD THEREOF, AND DISPLAY APPARATUS - The present disclosure discloses a light-splitting material and a preparation method thereof, a grating and an application method thereof, and a display apparatus. The light-splitting material comprises a liquid crystal mixture and an ethylene-vinyl acetate copolymer, wherein the liquid crystal mixture comprises a negative nematic liquid crystal, a chiral additive and an ionic liquid, and the mass ratio of the liquid crystal mixture to the ethylene-vinyl acetate copolymer is in a range of 3/7 to 8/2. In the present disclosure, since it is not required to continuously apply an electric field to the grating upon 2D display and 3D display, it is only required to apply an electric field upon the switching between 2D display and 3D display, it is possible to reduce the energy consumption of 3D liquid crystal display apparatuses, improve the display effect, and elongate the stand-by time. | 2018-06-07 |
20180155625 | LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME - The present invention relates to liquid-crystalline media comprising
| 2018-06-07 |
20180155626 | SUBSTANCE VEHICLE OF PYROLYSIS REACTOR - The present invention discloses a substance vehicle of pyrolysis reactor to apply for loading the substances of pyrolysis reactor. The substance vehicle includes a vehicle body, at least two movable doors and at least two fixed units. The vehicle body is used to accommodate the pyrolysis substances, and the movable door is movably disposed at the bottom of the vehicle body. When the fixed units are changed from the first position to the second position, a part of the fixed unit will disengage from the bottom of the movable door, such that the movable doors are opened by gravity and the pyrolysis substances are dropped. | 2018-06-07 |
20180155627 | SYSTEMS AND METHODS FOR IMPROVING QUENCHED COKE RECOVERY - The present technology is generally directed to systems and methods for improving quenched coke recovery. More specifically, some embodiments are directed to systems and methods utilizing one or more of a screen, barrier, or reflector panel to contain or redirect coke during or after quenching. In a particular embodiment, a quench car system for containing coke includes a quench car having a base, a plurality of sidewalls, and a top portion. The system can further include a permeable barrier covering at least a portion of the top of the quench car, wherein the permeable barrier has a plurality of apertures therethrough. | 2018-06-07 |
20180155628 | Surfactant composition and method for treating bitumen froth - The invention relates to a surfactant composition comprising an ionic liquid prepared from an unsubsituted or substituted primary, secondary or tertiary amine, or from an unsubstituted or substituted pyridine, amidine or guanidine with at least one fatty acid and/or resin acid. The invention also relates to a method for treating bitumen froth from a separation process, where bitumen is separated from mineral solids. The method comprises addition of said surfactant composition to the diluent and/or to the froth before phase separation. | 2018-06-07 |
20180155629 | BITUMEN THAT IS SOLID AT AMBIENT TEMPERATURE - Granular bitumen that is solid at ambient temperature includes a core and a coating layer that covers all or part of the surface of the core, wherein the core includes at least one bitumen base, and the coating layer includes at least one viscosifying compound and at least one anticaking compound. A method for manufacturing bitumen that is solid at ambient temperature and the use of bitumen that is solid at ambient temperature as a road binder, particularly for manufacturing asphalts. Further, a method for manufacturing asphalts from solid bitumen and to a method for transporting and/or storing road bitumen that is solid at ambient temperature. | 2018-06-07 |
20180155630 | METHOD AND SYSTEM FOR FLOTATION SEPARATION IN A MAGNETICALLY CONTROLLABLE AND STEERABLE MEDIUM - The present invention provides new techniques related to magnetically controllable and/or steerable froth for use in separation processes of mineral-bearing ore and bitumen. Apparatus is provided featuring a processor configured to contain a fluidic medium having a material-of-interest and also having a surfactant with magnetic properties so as to cause the formation of a froth layer that contains at least some of the material-of-interest and is magnetically responsive; and a magnetic field generator configured to generate a magnetic field and provide non-mechanical mixing and steering/driving of the froth layer in the processor. The material-of-interest may be mineral-bearing ore particles or bitumen. The processor includes a flotation tank, a primary separation vessel (PSV), or a pipe, including a tailings pipeline. The pipe has a non-magnetic pipe section, and the magnetic field generator includes a magnetic coil arranged in relation to non-magnetic pipe section to generate the magnetic field and provide the non-mechanical mixing and steering/driving of the froth layer in the pipe. | 2018-06-07 |
20180155631 | COMBINED OLEFIN AND OXYGENATE CONVERSION FOR AROMATICS PRODUCTION - Systems and methods are provided for inclusion of olefins in the reaction environment for an oxygenate conversion process. For conversion processes involving a metal-promoted zeolitic catalyst, addition of olefins to an oxygenate feed can reduce or minimize loss of aromatic selectivity as the catalyst is exposed to the feed. Additionally or alternately, for conversion processes involving a zeolitic catalyst including a zeolite other than an MFI framework type zeolite, addition of olefins to an oxygenate feed can reduce or minimize loss of activity for oxygenate conversion as the catalyst is exposed to the feed. | 2018-06-07 |
20180155632 | PROCESSES FOR STABILIZING A LIQUID HYDROCARBON STREAM - One or more processes for stabilizing a hydrocarbon stream. An unstabilized hydrocarbon stream comprising C5+ hydrocarbons and including some butane, propane and ethane, may be passed to a first separation zone. The first separation zone has an increased operating pressure so that a residue gas stream recovered from the first separation zone requires minimal compression for further processing. A bottoms stream form the first separation zone is passed to a second, lower pressure separation zone which provides an NGL stream and a C5+ liquid hydrocarbon stream that is stabilized. | 2018-06-07 |
20180155633 | PROCESS AND SYSTEM FOR CONVERSION OF CRUDE OIL TO PETROCHEMICALS AND FUEL PRODUCTS INTEGRATING DELAYED COKING OF VACUUM RESIDUE - Process scheme configurations are disclosed that enable conversion of crude oil feeds with several processing units in an integrated manner into petrochemicals. The designs utilize minimum capital expenditures to prepare suitable feedstocks for the steam cracker complex. The integrated process for converting crude oil to petrochemical products including olefins and aromatics, and fuel products, includes mixed feed steam cracking and gas oil steam cracking. Feeds to the mixed feed steam cracker include light products and naphtha from hydroprocessing zones within the battery limits, recycle streams from the C3 and C4 olefins recovery steps, and raffinate from a pyrolysis gasoline aromatics extraction zone within the battery limits. Feeds to the gas oil steam cracker include gas oil range intermediates from the vacuum gas oil hydroprocessing zone. Furthermore, vacuum residue is processed in a delayed coker unit to produce coker naphtha, which is hydrotreated and passed as additional feed to aromatics extraction zone and/or the mixed feed steam cracker, and coker gas oil range intermediates as additional feed to the gas oil hydroprocessing zone. | 2018-06-07 |
20180155634 | VISCOSITY REDUCTION OF CRUDE OIL THROUGH STRUCTURE DETERMINATION OF ASPHALTENE MOLECULE - Asphaltene may be effectively broken into smaller molecules by first elucidating the structure of the asphaltene and then developing a catalyst system based on the elucidated structure. The structure may be determined based on a series of analytical techniques including NMR, FTIR, Raman spectroscopy, XPS, and LDI. The most probable structure is determined using computational methods based on quantum mechanics and classical molecular dynamics and the catalyst system is developed for the most probable structure. | 2018-06-07 |
20180155635 | INTEGRATED PROCESS FOR IN-SITU ORGANIC PEROXIDE PRODUCTION AND OXIDATIVE HETEROATOM CONVERSION - An oxidative treatment process, e.g., oxidative desulfurization or denitrification, is provided in which the oxidant is produced in-situ using an aromatic-rich portion of the original liquid hydrocarbon feedstock. The process reduces or replaces the need for the separate introduction of liquid oxidants such as hydrogen peroxide, organic peroxide and organic hydroperoxide in an oxidative treatment process. | 2018-06-07 |
20180155636 | PROCESS FOR THE PRODUCTION OF BIODEGRADABLE HYDROCARBON FLUIDS BY HYDROGENATION - The invention provides for a fluid having a boiling point in the range of from 100 to 400° C. and comprising more than 95% isoparaffins and containing less than 100 ppm aromatics, obtainable by the process comprising the step of catalytically hydrogenating a feed comprising more than 95% by weight of a hydrodeoxygenated isomerized hydrocarbon biomass feedstock, at a temperature from 80 to 180° C. and at a pressure from 50 to 160 bars. The invention also provides for a fluid having a boiling point in the range of from 100 to 400° C. and a boiling range below 80° C., said fluid comprising more than 95% isoparaffins and less than 3% of naphthens by weight and having a ratio of isoparaffins to n-paraffins of at least 12:1, a biodegradability at 28 days of at least 60%, as measured according to the OECD 306 standard, a biocarbon content of at least 95% by weight, and containing less than 100 ppm aromatics by weight. The invention finally provides for uses of the fluid. | 2018-06-07 |
20180155637 | INTEGRATED OXYGENATE CONVERSION AND OLEFIN OLIGOMERIZATION - Systems and methods are provided for integration of an oxygenate conversion process with an olefin oligomerization process. The integrated process can produce gasoline of a desired octane and/or distillate fuel of a desired cetane. | 2018-06-07 |
20180155638 | PROCESS AND SYSTEM FOR CONVERSION OF CRUDE OIL TO PETROCHEMICALS AND FUEL PRODUCTS INTEGRATING STEAM CRACKING AND CONVERSION OF NAPHTHA INTO CHEMICAL RICH REFORMATE - Process scheme configurations are disclosed that enable conversion of crude oil feeds with several processing units in an integrated manner into petrochemicals. The designs utilize minimum capital expenditures to prepare suitable feedstocks for the steam cracker complex. The integrated process for converting crude oil to petrochemical products including olefins and aromatics, and fuel products, includes mixed feed steam cracking and conversion of naphtha to chemical rich reformate. Feeds to the mixed feed steam cracker include light products from hydroprocessing zones within the battery limits, recycle streams from the C3 and C4 olefins recovery steps, and raffinate from a pyrolysis gasoline aromatics extraction zone within the battery limits. Chemical reformate from straight run naphtha streams is used as an additional feed to the aromatics extraction zone and or the mixed feed steam cracker. Feeds to the gas oil steam cracker include hydrotreated gas oil range intermediates from the vacuum gas oil hydroprocessing zone. | 2018-06-07 |
20180155639 | PROCESS AND SYSTEM FOR CONVERSION OF CRUDE OIL TO PETROCHEMICALS AND FUEL PRODUCTS INTEGRATING VACUUM RESIDUE CONDITIONING AND BASE OIL PRODUCTION - Process scheme configurations are disclosed that enable conversion of crude oil feeds with several processing units in an integrated manner into petrochemicals. The designs utilize minimum capital expenditures to prepare suitable feedstocks for the steam cracker complex. The integrated process for converting crude oil to petrochemical products including olefins and aromatics, and fuel products, includes mixed feed steam cracking and gas oil steam cracking. Feeds to the mixed feed steam cracker include one or more naphtha fractions from hydroprocessing zones within the battery limits, including vacuum residue hydrocracking, within the battery limits, recycle streams from the C3 and C4 olefins recovery steps, and raffinate from a pyrolysis gasoline aromatics extraction zone within the battery limits. Feed to the gas oil steam cracker in certain embodiments includes gas oil range intermediates from the vacuum residue hydrocracking zone. In addition, a base oil production center is integrated to provide base oils product used for production of synthetic lubes or corresponding lube oil feedstocks | 2018-06-07 |
20180155640 | MERCAPTAN MANAGEMENT IN SELECTIVE HYDRODESULFURIZATION OF FCC NAPHTHA - A process for reducing the sulfur content of FCC naphtha is described. The process includes introducing a FCC naphtha feed to a selective hydrogenation zone to form a hydrogenated feed. The hydrogenated feed is separated into light fraction and a heavy fraction. The heavy fraction is introduced into a selective hydrodesulfurization zone to form a desulfurized stream which contains mercaptans. The desulfurized stream is separated into a mercaptan rich stream and a mercaptan lean stream. The mercaptan rich stream is treated with a caustic extraction process, a hydrodesulfurization reaction zone, a selective hydrogenation process, an adsorption process, or an ionic liquid extraction process to remove at least a portion of the mercaptan compounds to form a second mercaptan lean stream. | 2018-06-07 |
20180155641 | PROCESS AND SYSTEM FOR CONVERSION OF CRUDE OIL TO PETROCHEMICALS AND FUEL PRODUCTS INTEGRATING VACUUM RESIDUE HYDROPROCESSING - Process scheme configurations are disclosed that enable conversion of crude oil feeds with several processing units in an integrated manner into petrochemicals. The designs utilize minimum capital expenditures to prepare suitable feedstocks for the steam cracker complex. The integrated process for converting crude oil to petrochemical products including olefins and aromatics, and fuel products, includes mixed feed steam cracking and gas oil steam cracking. Feeds to the mixed feed steam cracker include one or more naphtha fractions from hydroprocessing zones within the battery limits, including vacuum residue hydrocracking, within the battery limits, recycle streams from the C3 and C4 olefins recovery steps, and raffinate from a pyrolysis gasoline aromatics extraction zone within the battery limits. Feeds to the gas oil steam cracker include gas oil range intermediates from the vacuum gas oil hydroprocessing zone and the vacuum residue hydrocracking zone. | 2018-06-07 |
20180155642 | PROCESS AND SYSTEM FOR CONVERSION OF CRUDE OIL TO PETROCHEMICALS AND FUEL PRODUCTS INTEGRATING STEAM CRACKING, FLUID CATALYTIC CRACKING, AND CONVERSION OF NAPHTHA INTO CHEMICAL RICH REFORMATE - Process scheme configurations are disclosed that enable conversion of crude oil feeds with several processing units in an integrated manner into petrochemicals. The designs utilize minimum capital expenditures to prepare suitable feedstocks for the steam cracker complex. The integrated process for converting crude oil to petrochemical products including olefins and aromatics, and fuel products, includes mixed feed steam cracking, fluid catalytic cracking and conversion of naphtha to chemical rich reformate. Feeds to the mixed feed steam cracker include light products from hydroprocessing zones within the battery limits, recycle streams from the C3 and C4 olefins recovery steps, and raffinate from a pyrolysis gasoline and FCC naphtha aromatics extraction zone within the battery limits. Chemical reformate from straight run naphtha streams is used as an additional feed to the aromatics extraction zone and or the mixed feed steam cracker. | 2018-06-07 |
20180155643 | PROCESS AND SYSTEM FOR CONVERSION OF CRUDE OIL TO PETROCHEMICALS AND FUEL PRODUCTS INTEGRATING SOLVENT DEASPHALTING OF VACUUM RESIDUE - Process scheme configurations are disclosed that enable conversion of crude oil feeds with several processing units in an integrated manner into petrochemicals. The designs utilize minimum capital expenditures to prepare suitable feedstocks for the steam cracker complex. The integrated process for converting crude oil to petrochemical products including olefins and aromatics, and fuel products, includes mixed feed steam cracking and gas oil steam cracking. Feeds to the mixed feed steam cracker include light products and naphtha from hydroprocessing zones within the battery limits, recycle streams from the C3 and C4 olefins recovery steps, and raffinate from a pyrolysis gasoline aromatics extraction zone within the battery limits. Feeds to the gas oil steam cracker include hydrotreated gas oil range intermediates from the vacuum gas oil hydroprocessing zone. Furthermore, vacuum residue is processed in a solvent deasphalting unit to produce deasphalted oil as additional feed to the gas oil hydroprocessing zone. | 2018-06-07 |
20180155644 | POLYMERIC DISPERSANTS FOR PETROLEUM PROCESS STREAMS - Disclosed herein are methods and compositions for reducing fouling by natural and synthetic foulants that tend to precipitate during petroleum collecting, processing, transporting, and storing. The method includes applying one or more antifouling polymers to a petroleum product to form a treated petroleum product, wherein fouling by the treated petroleum product is reduced and a stable dispersion is formed over a wide range of processing conditions. The one or more antifouling polymers include the polymerized residues of one or more α-olefins and maleic anhydride, further wherein the maleic anhydride residues are reacted with a primary amine. Concentrates of the antifouling polymers in solvents are stable and pourable at temperatures of 0° C. to −40° C. | 2018-06-07 |
20180155645 | ANTIFOULING COMPOSITIONS FOR PETROLEUM PROCESS STREAMS - Disclosed herein are antifouling compositions including a combination of one or more dispersant polymers and one or more inhibitors, the one or more dispersant polymers including the polymerized residues of one or more α-olefins and maleic anhydride, further wherein the maleic anhydride residues are reacted with a primary amine; and the one or more inhibitors including a functionalized p-phenylene diamine. Concentrates of the antifouling compositions in solvents are stable and pourable at temperatures of 0° C. to −40° C. The antifouling compositions are added to a petroleum product to form a treated petroleum product, wherein fouling by the treated petroleum product is reduced and a stable dispersion is formed over a wide range of processing conditions. | 2018-06-07 |
20180155646 | GAS OIL COMPOSITION AND METHOD FOR PRODUCING THE SAME - A gas oil composition comprising at least 20.0% by volume total aromatic content, at least 1.0% by volume bicyclic aromatic content, at least 0.2% by volume trior higher cyclic aromatic content, no more than 18.0% by mass naphthenobenzenes, and no more than 10 ppm by mass sulfur content, and having a density (15° C.) of at least 0.8200 g/cm3, and an ASTM colour of at least 0.2, characterised in that the gas oil composition is obtained by hydrogenation-desulfurisation of the stock oil described below, which contains cracked gas oil fraction: stock oil comprising at least 25.0% by volume total aromatic content, at least 15.0% by mass total naphthene content, at least 4.0% by mass bicyclic naphthene content, at least 1.0% by mass tricyclic naphthene content, and at least 0.50% by mass sulfur content, and having a 90% distillation temperature of at least 340.0° C. The gas oil composition of the present invention has excellent oxidative stability. | 2018-06-07 |
20180155647 | LOW SULFUR MARINE BUNKER FUELS AND METHODS OF MAKING SAME - This invention relates to low sulfur marine bunker fuel compositions and methods of making the same. The invention also relates to an uncracked, hydrotreated vacuum resid for use in making the low sulfur marine bunker fuel composition. Contrary to conventional marine/bunker fuel compositions, the low sulfur marine/bunker fuel composition uses mostly uncracked components, including a (cat feed) hydrotreated vacuum resid. The low sulfur marine/bunker fuel composition can also have reduced contents of residual components. | 2018-06-07 |
20180155648 | Aviation Gasoline Containing Branched Aromatics with a Manganese Octane Enhancer - An improved aviation gasoline formulation includes a branched aromatic composition to improve the Motor Octane Number of the fuel. Specifically, the branched aromatic composition includes an aromatic functional group covalently bonded to a branched alkyl group. The branched aromatic composition is used in the aviation gasoline together with a manganese-containing compound to enable the fuel to meet MON requirements. | 2018-06-07 |
20180155649 | Biogas Blending and Verification Systems and Methods - A biogas blending and energy content verification system and method for controlled enhancement of a biogas feedstock stream energy content profile by selective sampling and analysis of the biogas feedstock stream and controlled injection of a refined gas of a known, higher energy content into the biogas feedstock stream to produce a blended biogas having an augmented energy content profile meeting or exceeding a pre-established minimum to meet end user requirements. | 2018-06-07 |
20180155650 | Method and apparatus for agglomerating hydrophobic particles - The present invention provides a method and apparatus for agglomerating hydrophobic particles from a feed slurry. The method comprises adding a binder to a feed stream and conveying the feed stream and binder to an agglomerating device. The binder comprises 50% or more by volume of a non-hydrophobic substance. A high shear is applied to the feed stream and the binder in the agglomerating device to cause the hydrophobic particles to collide and bind to the binder, thereby agglomerating the hydrophobic particles. The agglomerated hydrophobic particles and the binder are removed from the feed stream. A method and apparatus for dewatering an agglomerated product is also provided, the agglomerated product comprising agglomerated hydrophobic particles held together by a binder comprising 50% or more by volume of a non-hydrophobic substance. | 2018-06-07 |
20180155651 | WATER-CONTAINING LUBRICATING FILM AGENT, SURFACE TREATED METALLIC MATERIAL, AND METHOD FOR FORMING WATER-CONTAINING LUBRICATING FILM OF METALLIC MATERIAL - A water-containing lubricant coating agent, used in metal plastic working, includes a water content of 3 to 50 mass %, at least one lipophilic lubricating component (A) and/or at least one solid lubricant (B) with cleavability dispersed in water, and at least one water-soluble lubricating component (C) selected from fatty acid components having 12 to 20 carbon atoms; wherein a mass ratio of (C)/[(A)+(B)]=0.05 to 0.5. | 2018-06-07 |
20180155652 | WINTERIZATION OF FISH OIL - The present invention relates to a process for winterizing crude fish oil by an improved winterization process, wherein a solubilizing agent is added to the fish oil prior to the winterization. The solubilizing agent is preferably a fat-soluble edible organic compound, such as fatty acids or fatty acid mixtures. The invention further relates to compositions obtainable by the process. | 2018-06-07 |
20180155653 | NOVEL ANIONIC SURFACTANTS AND WASHING AGENTS CONTAINING SAID SURFACTANTS - Surfactants of general formula (I), in which R | 2018-06-07 |
20180155654 | ANIONIC SURFACTANTS AND DETERGENTS COMPRISING THEM - Surfactants of the general formula (I) in which R | 2018-06-07 |
20180155655 | COMPOSITION - A dishwasher detergent composition, preferably pH neutral, and comprising a strong biodegradable builder and optionally a bleach, and optionally a sulfonated polymer. | 2018-06-07 |
20180155656 | LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS - A laundry care composition including at least one laundry care ingredient and at least one leuco polymer including a polymeric carbohydrate and a leuco moiety. The polymeric carbohydrate and the leuco moiety are covalently bound. Methods of making the leuco polymer, laundry care compositions comprising the leuco polymer and methods of treating textiles with such laundry care compositions. | 2018-06-07 |
20180155657 | LAUNDRY DETERGENT COMPOSITION - The present invention provides a domestic laundry cleaning composition, said composition comprising an anionic surfactant, an alkyl ether carboxylic acid dispersant; and a lipid esterase. | 2018-06-07 |
20180155658 | CLEANING COMPOSITIONS INCLUDING ENZYME AND BLEACH - Cleaning compositions that include an extracellular-polymer-degrading enzyme selected from the group consisting of endo-beta-1,6-galactanase enzymes, mannanase enzymes and mixtures thereof, a peroxygen source; and a bleach catalyst and methods of making and using such cleaning compositions to provide stain and soil removal and/or malodour reduction. | 2018-06-07 |
20180155659 | STORAGE STABLE LIQUID WASHING OR CLEANING AGENT CONTAINING PROTEASE AND CELLULASE - According to the invention, storage stability in terms of cellulolytic activity is to be improved in a liquid washing or cleaning agent which comprises a protease and cellulase. This is achieved by the use of a protease which comprises an amino acid sequence which is at least 80% identical to the amino acid sequence specified in SEQ ID NO. 1 and which has the amino acid glutamic acid (E) or aspartic acid (D) or the amino acid asparagine (N) or glutamine (Q) or the amino acid alanine (A) or glycine (G) or serine (S) at position 99 in the count according to SEQ ID NO. 1. | 2018-06-07 |
20180155660 | TOILET RIM BLOCK AND RIM BLOCK CAGE - A toilet rim block which consists of an outer cover and a core, and to a rim block cage including the toilet rim block. The outer cover includes a first composition and the core includes a second composition. Preferably, the first and the second compositions differ from each other by at least one of the following features: different active substances, different concentration but same active substance, and different viscosity. The outer cover partly encloses the core, and the core protrudes on at least two faces of the toilet rim block right to the surface as a pole and is exposed. The toilet rim block is spherical and the second pole protrudes to the surface on the face of the toilet rim block opposite the first pole, and is exposed. | 2018-06-07 |
20180155661 | Water-Soluble Encapsulated PH Control Agent - The present invention is directed to materials and method of encapsulating chemical agents. In particular, the present invention is directed to compositions and methods of encapsulating a pH control agent in a water soluble polymer encapsulant. | 2018-06-07 |
20180155662 | PRESSURIZED BEVERAGE CONCENTRATES AND APPLIANCES AND METHODS FOR PRODUCING BEVERAGES THEREFROM - The present invention describes methods and devices in which concentrated beverage products, each packaged in a pressurized container, can be combined with liquids and/or other ingredients to produce one or more servings of a beverage. These products provide users with a convenient way to prepare both alcoholic and non-alcoholic beverages (including carbonated beverages) in various serving sizes and quantities by combining the pressurized beverage concentrate with (possibly carbonated) liquids and other ingredients. | 2018-06-07 |
20180155663 | PRESSURIZED BEVERAGE CONCENTRATES AND APPLIANCES AND METHODS FOR PRODUCING BEVERAGES THEREFROM - The present invention describes methods and devices in which concentrated beverage products, each packaged in a pressurized container, can be combined with liquids and/or other ingredients to produce one or more servings of a beverage. These products provide users with a convenient way to prepare both alcoholic and non-alcoholic beverages (including carbonated beverages) in various serving sizes and quantities by combining the pressurized beverage concentrate with (possibly carbonated) liquids and other ingredients. | 2018-06-07 |
20180155664 | MULTI-MICROWELL ARRAY FOR MULTI-CELLULAR ADJACENT CO-CULTURE - The invention provides a multi-microwell platform that enables co-culture of up to 4 cell types in discrete adjacent wells using either 2-dimension or 3-dimension culture conditions for up to 10 days. The microwells are made of poly-dimethyl siloxane (PDMS) and placed on top of glass or tissue culture plastic. Cells and culture media can be manually loaded and replaced using a pipette independently of passive pumping method, and without the need of vacuum-assisted filling or syringe pumps. The major advantages of the inventive multi-microwell platform are reduction in cell number required as compared to well-based culture platforms, compatibility with manual pipetting, well-readout instruments and ease of use as compared to other microfluidic approaches, cell migration limited which doesn't requires cell labeling or sorting for cell-type specific studies, and adjacent multi-cellular 2-D and 3-D culture conditions which is in contrast with current methods where studies with limited cell numbers among multiple cell types are difficult or impossible to perform. | 2018-06-07 |
20180155665 | CELL CULTURE APPARATUS AND CULTURE METHODS USING SAME - Cell culture apparatus for emulating gastrointestinal tract conditions and comprising at least two adjacent, microfluidic, cell cultivation channels separated by a permeable or semipermeable membrane, a first channel carrying gastrointestinal tract epithelial cells or tissues and a second channel carrying luminal and preferably mucosal microbiota, and wherein said second channel comprises one or more dwell chambers capable of providing a location for unattached luminal flora to reside away from any direct flow in said second channel, permits modelling of multiple sections of the gastrointestinal tract and control of retention times. | 2018-06-07 |
20180155666 | Low Surface Energy Coatings For Mammalian Cell Culture - A cultureware system is directed to maintaining viability of mammalian cells, and includes a disposable holding container having a cell receiver with a cell-receiving surface. The cell receiver consists of a cell-adhesion inducement material including a polystyrene material and a glass material. The system further includes a polytetrafluoroethylene (PTFE) coating lining the cell-adhesion inducement material of the cell-receiving surface, and a culture of adherent mammalian cells located within the cell receiver on the PTFE coating. In response to attachment interaction between the mammalian cells and the PTFE coating, a decreased cell adhesion results in a cell viability rate of at least about 60% to about 70% over a 72-hour culturing period, the cell viability rate being under 90% over the 72-hour culturing period if, in the absence of the PTFE coating, the mammalian cells are located directly on the cell-adhesion inducement material. | 2018-06-07 |
20180155667 | RETENTION SYSTEM - The present invention relates to a Disposable Bioprocess System consisting of a Single-Use-Bioreactor, a Single-Use-Pump and a single-use micro-organism retention filter. Combined most suitable for cultivation of suspended micro-organisms in a liquid media at high micro-organism concentration in a perfusion mode continuous process for expression of biological material. | 2018-06-07 |
20180155668 | BIOMANUFACTURING SUITE AND METHODS FOR LARGE-SCALE PRODUCTION OF CELLS, VIRUSES, AND BIOMOLECULES - The present invention provides a production module for large-scale production of cells and/or cell-derived products such as antibodies or virus; a production suite comprising a plurality of functionally connected production modules of the invention; and a method for large-scale production of cells and/or cell-derived products using the production modules and/or production suites of the invention. | 2018-06-07 |
20180155669 | Device for Mechanical and Hydrodynamic Microfluidic Transfection - Methods for introducing exogenous material into a cell are provided, which include exposing the cell to a transient decrease in pressure in the presence of the exogenous material. Also provided are devices for performing the method of the invention. | 2018-06-07 |
20180155670 | MICROBIAL EXPERIMENT COOLING AND TEMPERATURE-SENSING MULTIPURPOSE RACK - A multi-function cooling and thermo-sensitive rack includes horizontal bars, a base, positioning holes, connectors, a lateral frame, connecting holes, a temperature-displaying prompter, and N temperature sensors. The lateral frame and the base are connected through the connectors. The lateral frame and the base have their surfaces facing each other symmetrically provided with plural connecting holes thereon. The horizontal bars have two ends thereof received in the corresponding symmetrical connecting holes. The positioning holes are distributed over the surface of the base. The N temperature sensors have output ends thereof for outputting sensing signals connected with input ends of the temperature-displaying prompter for inputting the N temperature-sensing signals. The present invention is applied to apparatuses used in microbiology experiment. | 2018-06-07 |
20180155671 | AIRCRAFT FUEL TANK WITH A VISUAL CONTROL SYSTEM INSIDE THE TANK, RELATED AIRCRAFT AND VISUAL CONTROL METHOD - Aircraft fuel tank, which has a visual control system inside the tank, includes at least a side wall ( | 2018-06-07 |
20180155672 | METHOD FOR DEVELOPING MALARIA SPOROZOITES IN VITRO - Described in this application is a method for producing | 2018-06-07 |
20180155673 | METHOD FOR CULTURING ANIMAL CELL COMPOSITION, METHOD FOR PRODUCING ANIMAL CELL COMPOSITION USING SAME, AND ANIMAL CELL COMPOSITION - An object of the present invention is to obtain a thicker animal cell composition by a simple and less expensive method. Namely, an object of the present invention is to provide a method for culturing a thicker animal cell composition by eliminating the hypoxia associated with animal cell compositions, a method for producing an animal cell composition containing unicellular algae, and an animal cell composition. | 2018-06-07 |
20180155674 | YEAST STRAIN HAVING IMPROVED CAPABILITY FOR FERMENTING XYLOSE IN THE PRESENCE OF ACETIC ACID - The invention relates to a method for selecting a yeast strain having improved capability for fermenting a pentose, advantageously xylose, in the presence of organic acid, advantageously acetic acid, in non-dissociated form, in which at least one yeast strain that is capable of fermenting said pentose is consecutively cultured in the following two media: a first growth medium comprising said pentose as the only carbon source and said organic acid in non-dissociated form; a second growth medium comprising another carbon source as the only carbon source, advantageously glucose, free of said organic acid in non-dissociated form, the consecutive culture in at least said two growth media being repeated at least twice, in the presence of rising concentrations of organic acid in non-dissociated form. | 2018-06-07 |
20180155675 | Method for Dedifferentiating and Culturing Microbial Species - Methods and devices useful for reprogramming microbial cells to grow under different culture conditions are provided. The methods and devices can be used to prepare cultures of new, previously uncharacterized microbial species and for identifying laboratory conditions to culture, propagate, and study microbes that do not grow under standard laboratory conditions. The invention is also useful for characterizing microbiota, such as the communities of microorganisms inhabiting the human body and natural environments such as soil. | 2018-06-07 |
20180155676 | CELL CULTURING METHOD USING NUCLEIC ACID-CONTAINING MEDIUM - An object of the present invention is to provide an animal cell culture method which is high in protein productivity. | 2018-06-07 |
20180155677 | METHODS AND COMPOSITIONS FOR MAKING ANTIBODIES AND ANTIBODY DERIVATIVES WITH REDUCED CORE FUCOSYLATION - The invention provides methods and compositions for preparing antibodies and antibody derivatives with reduced core fucosylation. | 2018-06-07 |
20180155678 | PLACENTA-DERIVED MATRIX AND METHODS OF PREPARING AND USE THEREOF - The invention relates to placenta-derived matrix, methods of preparing, and methods of use thereof. The invention also relates to methods of culturing cells, delivering cells, promoting differentiation of stem cells or tissue-specific progenitor cells, and repairing, replacing, regenerating, filling, reducing or inhibiting scarring of defects using the same. The invention further relates to methods of coating placenta-derived matrix on a surface or injecting the placenta-derived matrix into a site of interest. | 2018-06-07 |
20180155679 | CELL CULTURING METHOD AND KIT - The present invention relates to a cell culturing method and kit. More specifically, it relates to a cell culturing method and kit using a support that is exposed to the air. It further relates to a method of culturing cells by allowing them to migrate onto a porous polyimide film. | 2018-06-07 |
20180155680 | ESTABLISHING PLURIPOTENCY IN MOUSE EMBRYONIC STEM CELLS - A method for derivation and maintenance of pluripotency in mouse embryonic stem (mES) cells is disclosed. The method includes isolating mES cells from mouse embryos in a culture medium including an R2i compound, and culturing the mES cells in a medium including the R2i compound or a transforming growth factor beta (TGF-β) signaling pathway inhibitor. The R2i compound includes combination of a transforming growth factor beta (TGF-β) signaling pathway inhibitor and an extracellular signal-regulated kinases (ERK) signaling pathway inhibitor. This method can facilitate the homogeneous expression of pluripotency factors in embryonic stem cells. | 2018-06-07 |
20180155681 | MESODERM AND DEFINITIVE ENDODERM CELL POPULATIONS - The present invention provides cell populations that are enriched for mesendoderm and mesoderm, and cell populations that are enriched for endoderm. The cell populations of the invention are useful for generating cells for cell replacement therapy. The present invention further provides a method of generating hepatocytes, cell populations enriched for hepatocytes, and a method of hepatocyte replacement therapy. | 2018-06-07 |
20180155682 | METHOD FOR INDUCING DIFFERENTIATION OF NEURAL CREST CELLS INTO NEURONS OF THE AUTONOMIC NERVOUS SYSTEM - Provided is a method for inducing differentiation of neural crest cells into neurons of the autonomic nervous system, the method including the step of culturing neural crest cells in the presence of at least one of a BMP signaling pathway activator, an SHH signaling pathway inhibitor, and a Wnt signaling pathway inhibitor. | 2018-06-07 |
20180155683 | Methods and Compositions for Somatic Cell Proliferation and Viability - Methods and compositions for somatic cell proliferation as well as increasing viability of somatic cells are provided. The compositions include heparin binding protein isolated from a medium conditioned by growth of pluripotent stem cells, such as, human embryonic stem cells, human embryonic carcinoma cells. The methods include contacting a somatic cell with a heparin binding protein composition for a sufficient period of time to provide for enhanced proliferation and/or viability of the somatic cell as compared to the absence of the heparin binding protein composition. | 2018-06-07 |
20180155684 | Neural Progenitor Cell Differentiation - Differentiation and stability of neural stem cells can be enhanced by in vitro or in vivo culturing with one or more extracellular matrix (ECM) compositions, such as collagen I, IV, laminin and/or a heparan sulfate proteoglycan. In one aspect of the invention, adult mammalian enteric neuronal progenitor cells can be induced to differentiate on various substrates derived from components or combinations of neural ECM compositions. Collagen I and IV supported neuronal differentiation and extensive glial differentiation individually and in combination. Addition of laminin or heparan sulfate to collagen substrates unexpectedly improved neuronal differentiation, increasing neuron number, branching of neuronal processes, and initiation of neuronal network formation. In another aspect, neuronal subtype differentiation was affected by varying ECM compositions in hydrogels overlaid on intestinal smooth muscle sheets. The matrix compositions of the present invention can be used to tissue engineer transplantable innervated GI smooth muscle constructs to remedy aganglionic disorders. | 2018-06-07 |
20180155685 | METHOD FOR INDUCING OLIGODENDROCYTE PRECURSOR CELLS FROM OCT4-INDUCED HUMAN SOMATIC CELLS THROUGH DIRECT REPROGRAMMING - Provided is a method of inducing oligodendrocyte precursor cells (OPCS) through direct reprogramming from human somatic cells into which a nucleic acid molecule encoding an Oct4 protein or Oct4 protein-treated human somatic cells. The method of inducing OPCs by treating Oct4-overexpressing human somatic cells with a low molecular weight substance may establish OPCs with high efficiency in a short period of time through direct reprogramming without via neural stem cells, and thus the OPCs are useful as a cell therapeutic agent for an intractable demyelinating disease. | 2018-06-07 |
20180155686 | MEANS AND METHODS FOR GENERATION OF BREAST STEM CELLS - The present invention is in the field of stem cell biology, in particular in the field of developmental and regenerative biology. The invention generally relates to a method of generating cells capable of differentiating to a multicellular organoid unit that morphologically and/or functionally resembles the terminal ductal-lobular unit. More precisely, said cells are generated by dissociating mammary epithelial tissue, thereby gaining cells and culturing said cells in presence of a compound which elevates cAMP levels in a collagen gel. Under said culturing conditions said cells form a multicellular organoid unit facilitating to obtain a breast stem cell by isolating a single cell from said multicellular organoid unit. The present invention also relates to enriching said cells and differentiating them to a multicellular organoid that morphologically and/or functionally resembles the terminal ductal-lobular unit and use of said cells or said multicellular organoid in testing a compound. Furthermore, the present invention relates to a composition comprising said breast stem cells or the multicellular organoid. | 2018-06-07 |
20180155687 | HORMONE RESPONSIVE TISSUE CULTURE SYSTEM AND USES THEREOF - The invention provides tissue culture system for primary cells (e.g. normal mammalian primary epithelial progenitors). This system includes: a) a serum-free, chemically defined cell culture media; and, b) methods for isolation and in vitro long-term propagation of primary cells (e.g. primary epithelial cells). Primary cells so isolated and cultured can be kept undifferentiated and proliferate for many weeks (>15 weeks) or population doubling (>35 PD) without senescence, or any detectable genetic alterations. Upon changing media/culture conditions, these cells can be induced to differentiate. | 2018-06-07 |
20180155688 | METHOD FOR GENERATING HUMAN DENDRITIC CELLS FOR IMMUNOTHERAPY - In various embodiments methods of producing a cell population enriched for CLEC9A+ dendritic cells are provided where the methods involve culturing stem cells and/or progenitor cells in a cell culture comprising culture medium, a notch ligand, stem cell factor (SCF), FLT3 ligand (FLT3L); thrombopoietin (TPO); and IL-3 and/or GMCSF. | 2018-06-07 |
20180155689 | METHOD FOR IN VITRO EXPANSION OF ERYTHROID CELLS - The present invention relates to a method for in vitro expansion of mature erythroid cells. More specifically, the present invention relates to a method for obtaining concentrated erythrocytes by culturing erythroid cells at high density so as to allow the cells to physically and directly come in contact with each other. Particularly, the method of the present invention is very useful in that it is possible to obtain a large amount of clinically useful concentrated erythrocytes through a small container such as a test tube-sized bioreactor. | 2018-06-07 |
20180155690 | METHOD FOR PREPARING NATURAL KILLER CELLS USING IRRADIATED PBMCS, AND ANTI-CANCER CELL THERAPEUTIC AGENT COMPRISING THE NK CELLS - Provided is a method for preparing natural killer cell with high efficiency using irradiated peripheral blood mononuclear cells, more particularly to a method for proliferating highly activated NK cells using a combination of irradiated peripheral blood mononuclear cells (PBMCs) and a CD16 antibody and an anti-cancer cell therapeutic composition containing the natural killer cells (NK cells) prepared thereby. Further provided is a method for large-scale proliferation of activated NK cells with high efficiency using a combination of irradiated peripheral blood mononuclear cells (PBMCs) and a CD16 antibody without the use of cancer cells or genetically modified feeder cells having safety issues as feeder cells. The highly purified and highly cytotoxic NK cells proliferated in large quantities can be used as an active ingredient of a cancer immunotherapeutic composition. | 2018-06-07 |
20180155691 | MECHANICAL APPARATUS AND METHOD FOR ISOLATING STROMAL VASCULAR FRACTION - Provided is an apparatus and process for isolation of stromal vascular fraction (SVF) following lipoaspiration. | 2018-06-07 |
20180155692 | METHODS AND COMPOSITIONS FOR CONVERTING NON-ENDOCRINE PANCREATIC TISSUE INTO INSULIN-PRODUCING CELLS - Compositions and methods are provided for generating islet-like cell clusters. The methods include culturing a whole non-islet pancreatic cell discard or cells sorted therefrom with an effective amount of a molecule having Bone Morphogenetic Protein (BMP) activity (e.g., a BMP polypeptide). The effective amount of said molecule having BMP activity (e.g., BMP polypeptide) is sufficient to induce the formation of islet-like cell clusters. The methods further include treating or attenuating insulin-deficiency disorders, including type 1 diabetes. In one non-limiting embodiment, an insulin-deficiency disorder in a subject is treated or attenuated by culturing a whole non-islet pancreatic cell discard or cells sorted therefrom with an effective amount of a molecule having BMP activity (e.g., a BMP polypeptide) such that tho formation of islet-like cell clusters occurs. A therapeutically effective amount of the islet-like cell clusters which produce insulin are then transplanted into a subject in need to treat the insulin-deficiency disorder. | 2018-06-07 |
20180155693 | Method of Differentiating Stem Cells - There is provided an improved efficient method for differentiating stem cells into pancreatic endoderm cells and pancreatic hormone expressing and secreting cells which express Pdx-1 and C-peptide. The invention further provides screening methods for detecting factors of interest that will affect the differentiation of the stem cells into pancreatic endoderm cells. | 2018-06-07 |
20180155694 | METHODS OF PRODUCING PLURIPOTENT STEM CELLS FROM CHONDROCYTES - Disclosed herein are methods of producing induced pluripotent stem cells from chondrocytes, and further, methods of producing chondrocytes from said induced pluripotent stem cells. The invention further provides methods of regenerating cartilaginous tissue. | 2018-06-07 |
20180155695 | Cell Having Ability to Form Stratified Epithelial Tissue, and Method for Producing Same - To convert directly from a somatic cell into a cell having the ability to form stratified epithelial tissue that can act as outer skin of the body, a method for producing a cell having the ability to form stratified epithelial tissue is provided, the method including the step of introducing into a somatic cell at least one gene expressed relatively strongly in a cell having the ability to form stratified epithelial tissue. | 2018-06-07 |
20180155696 | METHODS AND COMPOSITIONS RELATING TO VIRAL LATENCY - Disclosed are compositions and methods that relate generally to viruses, and more particularly to the agents and their identification and use of anti-HIV agents which cause latently infected cells to reactivate. | 2018-06-07 |
20180155697 | METHOD OF PREPARING RECOMBINANT ADENO-ASSOCIATED VIRUS AND RECOMBINANT BACULOVIRUS - A method for producing a recombinant adeno-associated virus (rAAV) and a recombinant baculovirus virus, the method including: (1) infecting an insect host packaging cell line with a corresponding recombinant baculovirus integrated with an rAAV genome ITR-GOI (gene of interest flanked by AAV inverted terminal repeats) and an AAV Cap gene or AAV Rep gene; (2) culturing the host packaging cell line infected with the recombinant baculovirus, so as to produce the recombinant adeno-associated virus; and (3) separating and purifying the recombinant adeno-associated virus obtained in (2). | 2018-06-07 |
20180155698 | POLYMERASES ENGINEERED TO REDUCE NUCLEOTIDE-INDEPENDENT DNA BINDING - Provided are engineered DNA polymerases exhibiting modified functionality, and polynucleotides encoding same. Modified features include: (1) reduced catalytic activity in the presence of magnesium ions and/or (2) reduced affinity for primed template nucleic acid molecules in the absence of cognate nucleotide, and an ability to discriminate between cognate and non-cognate nucleotides under low salt conditions. Sequencing By Binding™ procedures employing the engineered polymerases have certain advantages. The engineered polymerases can have other uses as well. | 2018-06-07 |
20180155699 | BETA-GALACTOSIDASE VARIANT HAVING HIGH TRANSGLYCOSYLATION ACTIVITY, AND USE THEREOF - The present invention relates to a beta-galactosidase mutant having high transglycosylation activity and containing a C-terminal deletion, and the use thereof and more. More specifically, the present invention relates to a beta-galactosidase mutant having a C-terminal deletion, a gene encoding the same, a recombinant vector containing the gene, a recombinant microorganism transformed with the gene or the recombinant vector, and a method for producing the beta-galactosidase mutant using the recombinant microorganism. Using the high transglycosylation activity of the beta-galactosidase mutant containing the C-terminal deletion according to the present invention, galactooligosaccharide can be efficiently produced in large amounts. | 2018-06-07 |
20180155700 | HETEROLOGOUS EXPRESSION OF TERMITE CELLULASES IN YEAST - The present invention provides for heterologous expression of termite and termite-associated symbiont cellulases. The cellulases can, for example, be codon-optimized and expressed in yeast host cells, such as the yeast | 2018-06-07 |
20180155701 | PROTEASES WITH MODIFIED PROPEPTIDE REGIONS - The present invention provides methods and compositions for the production of mature proteases in bacterial host cells. The compositions include polynucleotides encoding serine protease sequences with modified or heterologous propeptide regions; polypeptides comprising serine proteases with modified or heterologous propeptide regions; expression cassettes, DNA constructs, vectors, and chromosomes comprising such polynucleotides; and bacterial host cells comprising such polynucleotides. The methods include methods for enhancing the production of mature proteases in bacterial host cells (e.g. | 2018-06-07 |
20180155702 | MULTIPLY-SUBSTITUTED PROTEASE VARIANTS - Novel protease variants derived from the DNA sequences of naturally-occurring or recombinant non-human proteases are disclosed. The variant proteases, in general, are obtained by in vitro modification of a precursor DNA sequence encoding the naturally-occurring or recombinant protease to generate the substitution of a plurality of amino acid residues in the amino acid sequence of a precursor protease. Such variant proteases have properties which are different from those of the precursor protease, such as altered wash performance. The substituted amino acid residue equivalent to positions 7, 23, 26, 28, 29, 30, 31, 47, 66, 69, 73, 82, 85, 88, 90, 92, 93, 105, 113, 139, 148, 149, 150, 151, 178, 200, 201, 231, 233, 267 and/or 273 of | 2018-06-07 |