23rd week of 2012 patent applcation highlights part 52 |
Patent application number | Title | Published |
20120142505 | EXERCISE DEVICE - An exercise device has two handles between which a flywheel is suspended on a cord. By twisting the cord and repeatedly pulling on the handles, the flywheel is caused to rotate about its axis of rotation. The cord passes through two passages formed in the flywheel. The latter is a solid body which is pierced only by the passages. The passages run obliquely inclined with respect to the axis of rotation. The friction between the cord and the wall(s) of the passages is increased when the handles are pulled apart and, as a result, the flywheel is prevented from sliding along the rope, for instance downwardly when the exercise device is used vertically. | 2012-06-07 |
20120142506 | EXERCISE BAR ATTACHMENT AND METHOD - A device and method is described that can easily provide removable exercise bars from the angled portions of a structure and provide a pair of approximately horizontal bars for exercising. The method includes placing an attachment device having a pair of brackets onto co-planar and non-parallel support members. The attachment device brackets include opening for placing, removing, and securing the attachment to the support members. The height of the bars is provided according to the spacing the brackets and the support members. | 2012-06-07 |
20120142507 | Exercise Device with Knee Rest - An exercise device is disclosed. The exercise device includes an ankle rest structure and a housing. Within the housing, a drive mechanism is provided that is connected to the ankle rest structure. The drive mechanism moves the ankle rest in a reciprocating motion along a generally horizontal plane. The exercise device also includes a knee rest structure spaced away from the ankle rest and connected to the housing. In one embodiment, the knee rest is movable in a horizontal and vertical direction with respect to the housing. | 2012-06-07 |
20120142508 | Tool-Holder Gripper for Radial Presses - Tool-holder gripper for a multiple change of tools in a horizontal radial press having a set of jaws moving radially and axially, comprising a handle, a tool-holder disc, and angular centring devices acting in conjunction with a front flange of the press to angularly align the tools and jaws. The gripper is further provided with a radial, axial centring portion configured to abut against the front surface of at least one radial jaw when the tools and jaws are axially aligned but still disengaged, so that the subsequent axial advancement of the jaws is accompanied by a simultaneous axial reversing of the gripper. | 2012-06-07 |
20120142509 | PRINTED MATTER MANUFACTURING METHOD, PRINTED MATTER MANUFACTURING DEVICE, AND PRINTED MATTER - The printed matter manufacturing method includes the steps of providing a printed layer in a predetermined pattern on a substrate, and providing an open part penetrating through the substrate and the printed layer in an open part formation region. The printed matter manufacturing method has a step of providing a buffer layer for mitigating a shock imparted to the printed layer when the open part is provided, so that the buffer layer contacts the printed layer in at least a portion of a periphery of the open part formation region. | 2012-06-07 |
20120142510 | SHEET BUNDLE TREATMENT APPARATUS CONFIGURED TO PERFORM PROCESSES ON CREASE OF FOLDED SHEET BUNDLE - A sheet bundle treatment apparatus may include a folding device, a conveying unit, a flattening device, and a control unit. The folding device performs a folding process on a sheet bundle to produce a folded sheet bundle. The conveying unit conveys the folded sheet bundle. The flattening device performs a flattening process to press a folded portion of the sheet bundle from the folded portion toward a fore edge to flatten the folded portion after the conveyance of the sheet bundle. The control unit causes the sheet bundle to be conveyed at a first velocity when the flattening process is not to be performed, and causes the sheet bundle to be conveyed at a second velocity which is slower than the first velocity when the flattening process is to be performed, thereby stopping the sheet bundle at a position where the flattening process is to be performed. | 2012-06-07 |
20120142511 | Cross grain folder and method of folding including an extended lap - An apparatus includes a quarterfolder having a folding blade for folding newspapers or other products. A folding location of the quarterfolder being adjustable with respect to the newspapers. The folding location may, for example, be located at between about 10 inches and about 11 inches from an edge of the newspaper so as to create a newspaper having a first side with a height of at between about 10 inches and about 11 inches and a second side with a height of approximately 9 inches or less. The second side, may, for example, have a height of between about 1 inch and about 2 inches, or alternatively, between about 7 inches and about 8 inches, depending on the overall length of the newspaper. | 2012-06-07 |
20120142512 | Machine For The Manufacture Of Paper Cushions - The present invention relates to a machine for producing paper dunnage, which machine comprises a forming device ( | 2012-06-07 |
20120142513 | CONTINUOUSLY OPERATING CENTRIFUGE - A continuously operating centrifuge for centrifuging sugar massecuites has an upwardly flaring conical sieve basket ( | 2012-06-07 |
20120142514 | SYRINGE FOR SPECIFIC GRAVITY DISTINCTION AND FAT TISSUE COMPONENTS SEPARATING METHOD THEREWITH - A syringe for fat tissue components distinction including a specific gravity distinction member, and a fat tissue components separating method using the syringe. The syringe for distinguishing crude fat tissue components extracted from the human body into several fat tissue layers by specific gravity includes: a syringe main body in a cylindrical shape for storing the crude fat tissue components extracted from the human body, the syringe main body having a fat intake hole at a front end and an opening at a rear end; and a specific gravity distinction member disposed in the syringe main body and having a specific gravity smaller than about 1.0, wherein the specific gravity distinction member is movable into one of the fat tissue layers that has the same specific gravity as that of the specific gravity distinction member, thereby enabling fat tissue components distinction by specific gravity. | 2012-06-07 |
20120142515 | DIELECTRIC COMPOSITION FOR THIN-FILM TRANSISTORS - An electronic device, such as a thin-film transistor, includes a substrate and a dielectric layer formed from a dielectric composition. The dielectric composition includes a dielectric material, a crosslinking agent, and a thermal acid generator. In particular embodiments, the dielectric material comprises a lower-k dielectric material and a higher-k dielectric material. When deposited, the lower-k dielectric material and the higher-k dielectric material form separate phases. The thermal acid generator allows the dielectric layer to be cured at relatively lower temperatures and/or shorter time periods, permitting the selection of lower-cost substrate materials that would otherwise be deformed by the curing of the dielectric layer. | 2012-06-07 |
20120142516 | OPTICAL GLASS, GLASS MATERIAL FOR PRESS-MOLDING, AND OPTICAL ELEMENT - The disclosed is an optical glass having ultrahigh refractive index and high dispersion characteristics in the form of a refractive index nd exceeding 2.05 and an Abbe number vd of 18.5 or lower and of permitting the stable production of high-quality glass from a glass melt; and a glass material for press molding and an optical element comprised of the optical glass. The optical glass is in the form of an oxide glass and comprises, denoted as cationic percentages,
| 2012-06-07 |
20120142517 | OPTICAL GLASS - A high-refractivity low-dispersion optical glass that can be stably supplied and has excellent glass stability and that has coloring reduced, composed of in mass %, 5 to 32% of total of SiO | 2012-06-07 |
20120142518 | CEMENT-FREE REFRACTORY - A cement free refractory mixture contains aluminum oxide, silicon carbide, fumed silica, aluminum metal, an anti-oxidant, reactive alumina, and a carbon-bearing material. The mixture can be formed by conventional techniques to create refractory articles to contain or direct the flow of liquid metals. Refractory articles formed by the mixture do not require firing to achieve an initial cure. | 2012-06-07 |
20120142519 | OBTAINING CATALYSTS OF MMOS2 AND M/MOS2 WITH NANOMETRIC ADDITIVE OF SIO2, SYNTHESIZED IN AQUEOUS SOLUTION ASSISTED BY ULTRASOUND - A method for obtaining a promoted molybdenum sulfide catalyst and a promoted molybdenum sulfide added with a nanometric additive. The obtained catalyst exhibits an improved catalytic activity in hydrotreatment reactions, such as hydrodesulfurization, hydrodenitrogenation, and hydrogenation. The invention presents as an advantage, in addition to a low cost composition by their transition metals content, the activation of thiosalts precursor using an environmentally friendly atmosphere. | 2012-06-07 |
20120142520 | CONTROLLED ACTIVITY PYROLYSIS CATALYSTS - A catalyst system is disclosed for catalytic pyrolysis of a solid biomass material. The system comprises an oxide, silicate or carbonate of a metal or a metalloid. The specific combined meso and macro surface area of the system is in the range of from 1 m | 2012-06-07 |
20120142521 | PHOTOCATALYST-COATED BODY AND PHOTOCATALYTIC COATING LIQUID THEREFOR - A photocatalyst-coated body comprises a substrate and a photocatalyst layer provided on the substrate, the photocatalyst layer comprising photocatalyst particles of 1 part or more by mass and less than 20 parts by mass, inorganic oxide particles of 70 parts or more by mass and less than 99 parts by mass, and the dried substance of a hydrolyzable silicone of zero parts or more by mass and less than 10 parts by mass, provided that a total amount of the photocatalyst particles, the dried substance of the inorganic oxide particles and the hydrolyzable silicone is 100 parts by mass in terms of silica. The inorganic oxide particles have a number average particle diameter ranging from 10 nm or more to less than 40 nm calculated by measuring lengths of 100 particles randomly selected from particles located within a visible field magnified 200,000 times by a scanning electron microscope. | 2012-06-07 |
20120142522 | PROCESS AND APPARATUS FOR THE PRODUCTION OF USEFUL PRODUCTS FROM CARBONACEOUS FEEDSTOCK - A carbonaceous feedstock to alcohol conversion process in which carbon dioxide is removed from the syngas stream issuing from a feedstock reformer, to yield a carbon dioxide depleted syngas stream including hydrogen, carbon monoxide and methane. This carbon dioxide depleted syngas stream is then passed through a Fischer-Tropsch reactor ultimately yielding a mixed alcohol product which is preferably largely ethanol. The removed carbon dioxide stream is passed through a methane reformer along with methane, which is produced in or has passed through a Fischer-Tropsch reactor, to yield primarily carbon monoxide and hydrogen. The carbon monoxide and hydrogen stream from the methane reformer are passed through the alcohol reactor. Also disclosed are a unique catalyst, a method for controlling the content of the syngas formed in the feedstock reformer, and a feedstock handling system. | 2012-06-07 |
20120142523 | POROUS COMPOSITE METAL OXIDE, CATALYST USING THE SAME, AND METHODS FOR PRODUCING THE POROUS COMPOSITE METAL OXIDE AND THE CATALYST - A porous composite metal oxide, including a mixture of first ultrafine particles containing alumina and second ultrafine particles containing zirconia, wherein the first ultrafine particles and the second ultrafine particles are uniformly dispersed in such a way as to satisfy a condition that standard deviations of content ratios (% by mass) of all metal elements contained in the porous composite metal oxide at 0.1% by mass or more are each 10 or less, the standard deviations being obtained by measuring content ratios of the metal elements at 100 measurement points within a minute analysis region of 20 nm square by energy dispersive X-ray spectroscopy using a scanning transmission electron microscope equipped with a spherical aberration correction function. | 2012-06-07 |
20120142524 | NANOCRATER CATALYST IN METAL NANOPARTICLES AND METHOD FOR PREPARING THE SAME - Disclosed are a nanocrater catalyst in metal nanoparticles with a nanocrater form of hole structure in center of the catalyst which is useful for manufacturing nano-sized materials and/or articles with desired structure and characteristics, a preparation method thereof including a plasma etching and chemical etching process (“PTCE process”), and nano-sized materials and/or articles manufactured by using the nanocrater catalyst in metal nanoparticles. | 2012-06-07 |
20120142525 | POLYSACCHARIDE-INORGANIC COMPOSITE PARTICLES AS PERFORMANCE ADDITIVES FOR SUPER-ABSORBENT POLYMERS - The present invention relates to discrete particulate composite additives for superabsorbent polymers and includes a method of making same. The discrete particulate composite additives generally comprise a polysaccharide and an inert inorganic component. Advantageously, these discrete particulate composite additives functionally improve superabsorbent performance. They are suitable for a number of applications, including the use and manufacture of hygiene products. | 2012-06-07 |
20120142526 | METHOD FOR PRODUCING A CERAMIC FOAM HAVING REINFORCED MECHANICAL STRENGTH FOR USE AS A SUBSTRATE FOR A CATALYST BED - A method for manufacturing ceramic foam, including impregnating polymer foam having an open porosity with a first suspension of ceramic particles in a solvent; drying the impregnated polymer foam; heat treating the dried polymer foam by thermally decomposing the dried polymer foam; unbinding the organic compounds contained in the polymer foam, and pre-sintering the ceramic particles contained in the polymer foam; impregnating the polymer foam with a second suspension of ceramic particles in a solvent; drying the polymer foam, sintering the ceramic particles contained in the polymer foam. | 2012-06-07 |
20120142527 | INDICATOR, APPLICATION THEREOF AND RELATED PRODUCTS - There is disclosed an indicator composition, the application thereof to substrates, and related products. The indicator composition comprises an organic solvent soluble polymer and a redox sensitive material which displays different visible properties in the oxidised and reduced forms. The organic solvent soluble polymer can be at least partially sulfonated polystyrene. The indicator composition can be dissolved in organic solvents such as acetone, ethanol and ethyl acetate to form inks which can be used in a variety of printing processes. The indicator composition can be used to detect oxidising agents, oxygen, water, reducing agents, UV light, temperature and the passage of time. | 2012-06-07 |
20120142528 | Methods Employing Fungicidal Active Substance Combinations Containing Trifloxystrobin - What are described are novel active compound combinations comprising a known oxime ether derivative (trifloxystrobin) and imidacloprid, which combinations are highly suitable for controlling phytopathogenic fungi and insects. | 2012-06-07 |
20120142529 | NOVEL HERBICIDES - Compounds of formula (I), wherein the substituents are as defined in claim | 2012-06-07 |
20120142530 | PROTEIN COMPOSITIONS FOR PLANT TREATMENT - Disclosed herein are methods of accelerating root growth in a plant, the method comprising applying to the plant root a composition comprising a) a mixture of proteins and polypeptides, and b) a surfactant, whereby root growth is accelerated as compared to an untreated plant. Also disclosed herein are methods of improving the foliar uptake of a biologically active compound by a plant, the method comprising applying to the plant foliage a composition comprising a) a mixture of proteins and polypeptides, and b) a surfactant, whereby root growth is accelerated as compared to an untreated plant. | 2012-06-07 |
20120142531 | Coated Dehydrated Microorganisms with Enhanced Stability and Viability - The present invention relates to coated dehydrated microorganisms comprising a dehydrated microorganism surrounded by at least one coating, said coating comprising by dry weight at least 25% of hygroscopic salt(s) and wherein the pH of the coating is compatible with viability of the coated dehydrated microorganism. The coating can be partially crystalline, the salt(s) in the coating having preferably a crystallinity degree of up to 60% once applied onto the dehydrated microorganism. The present invention also relates to liquid coating compositions, methods for coating and protecting a dehydrated microorganism. Finally, the present invention relates to a method for the preparation of food products, feed products, consumer healthcare products or agri-products as well as to a food product, feed product, a consumer healthcare product or an agri-product containing such coated dehydrated microorgansims. | 2012-06-07 |
20120142532 | LOW VOLATILITY AUXIN HERBICIDE FORMULATIONS - Low volatility dicamba herbicide formulations are described. In some embodiments, concentrate formulations comprising dicamba monoethanolamine salt, dicamba potassium salt, or mixed dicamba salts are provided. In other embodiments, a dicamba salt is combined with a polybasic polymer. | 2012-06-07 |
20120142533 | REDUCED VAPORIZATION COMPOSITIONS AND METHODS - The present invention provides compositions, systems, and methods employing materials to reduce or eliminate vapor transfer of an active substance from a target surface to a non-target surface. In certain embodiments, a material is mixed with a liquid, gas, and/or solid comprising an active substance to form a mixture such that the mixture has a lower vapor pressure than the liquid, gas, and/or solid. In some embodiments, the active substance is a herbicide and the target surface is an agricultural field or crop. | 2012-06-07 |
20120142534 | GRANULAR COMPOSITIONS - In a first aspect of the present invention, there is provided a method of improving the cultivation of rice in a paddy comprising adding a granular composition to the water in said paddy, wherein said granular composition comprises one or more cyclopropene compound encapsulated in a molecular encapsulation agent. | 2012-06-07 |
20120142535 | HYDROLYSIS RESISTANT ORGANOMODIFIED TRISILOXANE IONIC SURFACTANTS - The present invention provides for a composition comprising a siloxane having the formula: | 2012-06-07 |
20120142536 | ENHANCING CRITICAL CURRENT DENSITY OF CUPRATE SUPERCONDUCTORS - The present invention concerns the enhancement of critical current densities in cuprate superconductors. Such enhancement of critical current densities include using wave function symmetry and restricting movement of Abrikosov (A) vortices, Josephson (J) vortices, or Abrikosov-Josephson (A-J) vortices by using the half integer vortices associated with d-wave symmetry present in the grain boundary. | 2012-06-07 |
20120142537 | SUPERCONDUCTING DIRECT CURRENT TRANSMISSION SYSTEM - A DC superconducting coaxial transmission system provides electrical transmission of 5,000 megawatts of energy while simultaneously delivering liquid hydrogen. The transmission system includes a coaxial transmission segment including an inner superconductor, an outer superconductor disposed in surrounding relation to the inner conductor, and a dielectric insulator disposed between the inner superconductor and the outer superconductor. Liquid hydrogen surrounds the superconductors. Three phase transformers and poly phase rectifier/inverters provide a DC voltage source to the superconductors from the electrical grid. In one embodiment, a switching circuit connected between the voltage source and the superconductor injects a cancellation current component into the direct current flow. The cancellation current component is polarized to flow in a direction opposite to the direct current flow to produce a current zero, thus enabling safe interruption of the high DC current while minimizing the magnitude of transient voltages during switching. | 2012-06-07 |
20120142538 | Superconducting Coil - A superconducting coil includes (a) a plurality of windings of a coil comprising high-temperature superconductors and (b) an electrically conductive channel in which the high-temperature superconductors are mounted. The high-temperature superconductors can comprise at least one of the following: Ba | 2012-06-07 |
20120142539 | MECHANICAL DECOUPLING IN HIGH-TEMPERATURE SUPERCONDUCTING TAPES - A novel method and structure for creating a high-temperature superconducting tape. The concept of the invention is to use a conductor insulation which not only electrically insulates the conductors of the coil windings from each other, but also mechanically insulates them from the much stronger encapsulant. The insulation material mechanically decouples the conductor from the encapsulant at the boundary between them, thereby preventing damage as a result of thermal and electromagnetic shearing forces. The proposed structure allows the encapsulant to continue performing its functions of preventing coarse motion and stabilizing the coil as a whole, while allowing fine relative displacements of individual coil windings caused by radial stress gradients. | 2012-06-07 |
20120142540 | Methods For Sequencing Nucleic Acid Molecules - Methods and compositions for determining the nucleic acid sequence of polynucleotides that are at least 1500 nucleotides in length are provided. | 2012-06-07 |
20120142541 | Structured Peptide Processing - The invention relates to a method for modifying one or more peptide ligands, comprising polypeptides covalently linked to a molecular scaffold at two or more amino acid residues, comprising the steps of providing one or more peptide ligands, wherein the polypeptide comprises two or more reactive groups which form a covalent linkage to the molecular scaffold, and at least one loop which comprises a sequence of two or more amino acids subtended between two of said reactive groups; exposing the peptide ligands to one or more proteases; and sorting the ligands according to the extent of proteolytic cleavage. | 2012-06-07 |
20120142542 | Metabolite Biomarkers for the Detection of Esophageal Cancer Using NMR - Methods for the detection and screening of esophageal adenocarcinoma (EAC) patients and for the monitoring of EAC treatment using a panel or panels of small molecule metabolite biomarkers are disclosed. In other aspects, methods for detection and screening for the progression of high-risk conditions (BE and HOD) to EAC and to monitoring treatment using a panel or panels of small molecule metabolite biomarkers are disclosed. The biomarkers are sensitive and specific for the detection of EAC, and can also be used to classify Barrett's esophagus (BE) and high-grade dysplasia (HOD), which are widely regarded as precursors of EAC. | 2012-06-07 |
20120142543 | Methods to assess treatment outcomes in Reward Deficiency Syndrome (RDS)behaviors utilizing expression profiling - The present invention relates to methods to objectively assess treatment outcomes in Reward Deficiency Syndrome (RDS) behaviors by obtaining expression profiles (e.g., mRNA expression and/or protein expression profiles) for one or more genes at two or more different time points, for example, before and after treating a subject known to have or suspected of having an RDS affliction. Analysis, for example, of mRNA and/or protein expression levels and/or patterns can be conducted before admission to a treatment facility, followed by testing at one or more various designated times during and after a subject's treatment. Such methods may also be combined with other tests, and can be used in diagnosis and treatment of RDS and RDS behaviors, including drug and/or alcohol abuse and addiction, overeating, gambling, sexual addiction, etc. | 2012-06-07 |
20120142544 | DIAGNOSTIC TRANSCRIPTOMIC BIOMARKERS IN INFLAMMATORY CARDIOMYOPATHIES - Molecular signatures that function as very sensitive diagnostic biomarker for myocarditis, heart disease and disorders thereof, are identified. | 2012-06-07 |
20120142545 | SOLID PHASE AND CATALYZED ENABLED AUTOMATED ISOTOPE DILUTION AND SPECIATED ISOTOPE DILUTION MASS SPECTROMETRY - A method for the equilibration of enriched isotope species and natural isotope species prior to mass spectrometric analysis using solid phase and/or microwave isotope ratio equilibration and measurement. | 2012-06-07 |
20120142546 | HYPOMETHYLATED GENES IN CANCER - The present invention provides methods and kits for identifying a cell that exhibits or is predisposed to exhibiting unregulated growth by detecting hypomethylation of a gene or a regulatory region in at least one gene in the cell. Also provided are methods for diagnosis or prognosis of a proliferative disorder in a subject. Also provided are methods of ameliorating a cell proliferative disorder in a subject by administering to the subject an agent that methylates a hypomethylated gene or regulatory region thereof. In some aspects, the gene or regulatory region thereof is TKTL1, H19, MAGEA2, MAGEA3, MAGEA4, MAGEA11, GPR1 7, GRTN1, C19ORF28, MAGEA12, MAGEA1, MAGEA5, NY-ESO-1, MAGEA9, MAGEA6, MAGEB2, CT45-2, SBSN, G6PD, ZNF711, CrispL, KRT86, KIPV467, KRT81, CSPG5, PP1R14A, KISS1R, KIAA1937 protein, SOX30, DEAD, or KBGP. | 2012-06-07 |
20120142547 | POLYPEPTIDE IMMOBILIZATION - The present invention provides a method, comprising (a) providing a reactant ligand attached to a substrate; (b) contacting the substrate with a fusion polypeptide, said fusion polypeptide comprising a capture polypeptide fused to a display polypeptide under conditions such that said reactant ligand covalently binds to said capture polypeptide; and (c) analyzing said display polypeptide. | 2012-06-07 |
20120142548 | METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND PROGNOSIS OF ALZHEIMER'S DISEASE - The invention relates to methods of diagnosing Alzheimer's disease (AD) in a subject and methods of determining the prognosis in patients with AD. The adhesion molecules P-selectin and L-selectin are described for the first time for use as biomarkers to aid in the diagnosis of AD. The invention further describes the use of one or more of L-selectin, MCP-1, IL-1α, IL-8 and IFN-γ to aid in the prognosis of either accelerated cognitive decline (ACD) or slow cognitive decline (SCD) in patients with AD. | 2012-06-07 |
20120142549 | RAF GENE FUSIONS - The present disclosure relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present disclosure relates to RAF gene fusions as diagnostic markers and clinical targets for cancer. | 2012-06-07 |
20120142550 | Vanin 1 as a Peripheral Blood Oxidative Stress Sensor - Aspects of the subject invention are drawn to methods, compositions, systems and kits for the assessment of oxidative stress in an individual from a blood sample. In certain embodiments, the expression level of VNN1 in blood cells from a subject (or patient) is assessed and used to determine the subject's oxidative stress state, where an increased/high expression level of VNN1 indicates that the subject is in a state of oxidative stress. Expression of VNN1, and optionally other genes, may be done by assessing nucleic acid and/or protein levels in the blood cells obtained from the subject. | 2012-06-07 |
20120142551 | Methods for Genotyping Selected Polymorphism - Methods for genotyping polymorphisms using a locus specific primer that is complementary to a region near a selected polymorphism are described. Methods for synthesizing pools of locus specific primers that incorporate some degenerate positions are also disclosed. A plurality of different sequence capture probes are synthesized simultaneously using degenerate oligonucleotide synthesis. The sequence of the locus specific regions of the capture probes are related in that they have some bases that are identical in each sequence in the plurality of sequences and positions that vary from one locus specific region to another. The sequences are selected based on proximity to a polymorphism of interest and because they conform to a similar sequence pattern. | 2012-06-07 |
20120142552 | HIGH-SENSITIVITY ASSAYS FOR PATHOGEN DETECTION USING METAL-ENHANCED FLUORESCENCE - The present invention relates to an assay including a surface having silver colloids or islands attached thereto. Attached to the surface and/or silver colloids/islands are polynucleotides which are complimentary to a target polynucleotide sequence. The assay is performed by adding the target polynucleotide sequence to the assay surface and allowed to hybridize with the capture polynucleotides. Fluorophore-labeled capture polynucleotides are added and hybridize to the target polynucleotide. Bound target polynucleotides are detected by metal enhanced fluorescence. | 2012-06-07 |
20120142553 | Molecular Markers in Kidney Cancer - The present invention relates to methods for establishing the presence, or absence, of a kidney, or renal, tumour in a human individual suspected of suffering from kidney, or renal, cancer. Specifically, the present invention relates to methods for establishing the presence, or absence, of a kidney tumour in a human individual suspected of suffering from kidney cancer comprising: a) determining the expression of one or more genes chosen from the group consisting of NDUFA4l2, ANGPTL4, EGLN3, PTHLH, and ATP6V1B1 in a sample originating from said human individual; b) establishing up, or down, regulation of expression of said one or more genes as compared to expression of said respective one or more genes in a sample originating from said human individual not comprising kidney tumour cells or tissue, or from an individual, or group of individuals, not suffering from kidney cancer; and c) establishing the presence, or absence, of a kidney tumour based on the established up- or down regulation of said one or more genes. | 2012-06-07 |
20120142554 | HIGH PRECISION QUANTITATIVE ASSAY COMPOSITION AND METHODS OF USE THEREFOR - The invention features compositions and methods that are useful for precisely determining the amount of one or more analytes present in a sample. In one aspect, the invention provides a composition for measuring the abundance of one or more target analytes in a sample, where the composition contains a set of detection units for each analyte fixed to a substrate (e.g.,a membrane, bead, filter, chip, polymer-based film or glass slide, or other printable surface), where each detection unit contains a discrete amount of a capture agent that specifically binds the target analyte, and the amount of capturing agent varies over the set to form a concentration gradient. | 2012-06-07 |
20120142555 | Compositions And Methods For Immunodominant Antigens of Mycobacterium Tuberculosis - Contemplated compositions, devices, and methods are drawn to various antigens from the pathogen | 2012-06-07 |
20120142556 | HIGH THROUGHPUT ASSAYS FOR DETERMINING CONTRACTILE FUNCTION AND DEVICES FOR USE THEREIN - The present invention provides high throughput assays for identifying compounds that modulate a contractile function, as well as devices suitable for use in these assays. | 2012-06-07 |
20120142557 | SLIDE CONDITIONING SYSTEMS AND METHODS - A slide-loader system for preparing a microarray slide having a hybridized reaction area for washing, and which includes an immersion tray which contains a volume of wash buffer fluid, and a stripping jig that holds the microarray slide during removal of a reaction chamber housing that is mounted about the hybridized reaction area. | 2012-06-07 |
20120142558 | DIAGNOSTIC LUNG CANCER PANEL AND METHODS FOR ITS USE - Disclosed herein are novel diagnostic lung cancer panels and the use of these panels to diagnose, predict, and characterize lung cancer and to monitor or predict treatment efficacy. | 2012-06-07 |
20120142559 | BIOMARKERS AND PARAMETERS FOR HYPERTENSIVE DISORDERS OF PREGNANCY - The application discloses new test panels comprising biomarkers and clinical parameters, for the prediction, diagnosis, prognosis and/or monitoring of hypertensive disorders of pregnancy and particularly preeclampsia; and related methods, uses, kits and devices. | 2012-06-07 |
20120142560 | HEPARAN SULFATE SYNTHESIS - The invention provides an efficient modular chemical synthesis for heparan sulfate oligosaccharides based on orthogonal protection strategies. Modular disaccharide building blocks, themselves the product of a novel combinatorial synthesis, are combined in numerous ways to produce a range of oligosaccharides. | 2012-06-07 |
20120142561 | EQUIVALENT CIRCULATING DENSITY CONTROL IN DEEP WATER DRILLING - A method of providing a substantially constant rheological profile of a drilling fluid over a temperature range of about 120° F. to about 40° F. includes adding a drilling fluid additive to the drilling fluid, wherein the drilling fluid additive includes the reaction product of a carboxylic acid with at least two carboxylic moieties; and a polyamine having an amine functionality of two or more. A composition, such as an oil based drilling fluid, includes the reaction product of a carboxylic acid with at least two carboxylic moieties and a polyamine having an amine functionality of two or more. | 2012-06-07 |
20120142562 | ORGANIC SALTS FOR REDUCING STONE PERMEABLITIES - The use of free, aromatic acids which contain at least two aromatic ring systems or at least two acid functions, and/or salts thereof, for influencing rock formations in the exploitation of underground mineral oil and/or natural gas deposits is described. The free acids are used in particular for influencing and especially controlling the flow of acid into rock formations in so-called acidizing methods. Suitable salts of said aromatic acids serve for reducing the rock permeability and in particular reducing the inflow of water into the well bore. In addition to this use, corresponding methods are also claimed. | 2012-06-07 |
20120142563 | Corrosion Inhibitor Compositions Comprising Reaction Products of Aldehydes and Amides and Related Methods - The invention relates to corrosion inhibitor compositions comprising products of a reaction between aldehydes and amides for use in subterranean applications and methods related thereto. In general, the methods for inhibiting corrosion comprise providing a corrosive environment and adding a composition comprising a corrosion inhibitor to the corrosive environment. The corrosion inhibitor comprises a product of a reaction between at least one aldehyde and at least one amide that is not formamide or a formamide derivative. | 2012-06-07 |
20120142564 | LUBRICATING OIL WITH ENHANCED PROTECTION AGAINST WEAR AND CORROSION - Provided is a lubricating oil composition comprising: (a) a major amount of an oil of lubricating viscosity; and (b) one or more borated alkaline earth metal alkyltoluene sulfonate detergents; wherein the lubricating oil composition comprises no more than about 0.20 wt. % of phosphorus and no more than about 0.50 wt. % of sulfur. | 2012-06-07 |
20120142565 | Antiwear Containing Lubricating Composition - The present invention relates to a lubricating composition containing a sulphur-free metal salt of a hydrocarbyl-substituted phosphorus compound and an organo-sulphide. The composition has a sulphur content of greater than 0.3 weight percent of sulphur. The invention further provides for a method of lubricating a driveline device by using a lubricating composition. | 2012-06-07 |
20120142566 | GREASE COMPOSITION AND MECHANICAL PART - The invention provides a grease composition containing a base oil, a thickener and an additive, characterized in that the base oil has a kinetic viscosity at 40° C. of 50 to 200 mm | 2012-06-07 |
20120142567 | METHOD FOR MAINTAINING ANTIWEAR PERFORMANCE OF TURBINE OILS CONTAINING POLYMERIZED AMINE ANTIOXIDANTS AND FOR IMPROVING THE DEPOSIT FORMATION RESISTANCE PERFORMANCE OF TURBINE OILS CONTAINING MONOMERIC AND/OR POLYMERIC ANTIOXIDANTS - The antiwear performance of turbine oils containing polymerized amine antioxidants and antiwear additives is maintained at or enhanced beyond the level as that of turbine oils containing monomeric amine antioxidants by employing as the antiwear additive a resorcinol bis(diphenylphosphate) (RDP). The deposit formation resistance performance of turbine oils containing monomeric and/or polymeric amine antioxidant is improved by employing RDP. | 2012-06-07 |
20120142568 | LUBRICATING COMPOSITION - The present invention provides a lubricating composition comprising a base oil (A) and a hydroxyl group-added poly(meth)acrylate (B). | 2012-06-07 |
20120142569 | CLEAR COSMETIC COMPOSITIONS CONTAINING LIPOPHILIC MATERIALS - The present invention is directed toward a composition comprising: (a) at least one alkoxylated monoamine; (b) at least one alkoxylated monoacid; (c) at least one lipophilic compound; (d) at least one surfactant; (e) optionally, at least one auxiliary ingredient; and (f) at least one cosmetically acceptable carrier; wherein the ratio by weight of (b):(a) is greater than 1 and wherein the ratio by weight of (a)+(b):(c) is greater than 2. The present invention also relates to methods for cleansing and conditioning keratinous substrates. The methods can provide hair with improved shine, condition, manageability, and styling ability. | 2012-06-07 |
20120142570 | HERBAL CLEANSING COMPOSITION AND METHOD OF PREPARING THE SAME - Disclosed herein is a herbal cleansing composition comprising extracts of herbs along with dehydroxanthan gum and alkylpolyglucoside and cosmeceutically acceptable excipients and method of preparing the same. | 2012-06-07 |
20120142571 | LOW IRRITANCY CLEANSING COMPOSITIONS - A low irritancy cleansing composition comprises: (a) an anionic surfactant compound of formula (I): wherein R | 2012-06-07 |
20120142572 | LOW IRRITANCY CLEANSING COMPOSITIONS - Composition A low irritancy cleansing composition comprises: (a) an anionic surfactant compound of formula (I): wherein R | 2012-06-07 |
20120142573 | USE OF MIXTURES FOR REMOVING POLYURETHANE FROM METAL SURFACES - Use of mixtures comprising | 2012-06-07 |
20120142574 | SODIUM METASILICATE BASED CLEANING SOLUTIONS - A cleaning solution used for cleaning oils and polluted industrial parts and a method for preparing cleaning solutions are disclosed. The cleaning solutions include (a) 1.0-5.5 wt-% alkali metasilicate agent, (b) 1.0-20.0 wt-% surface active agent, (c) 7.0-15.0 wt-% organic solvent, and (d) water. A method for preparing cleaning solutions includes the steps of (a) dissolving 1.0-8.0 wt-% alkali metasilicate powder in water forming a first solution, (b) dissolving 1.0-6.0 wt-% surface active agent and 7.0-20.0 wt-% organic solvent in a second solution, and (c) mixing the first and second solutions forming the cleaning solution. | 2012-06-07 |
20120142575 | AQUEOUS OZONE SOLUTION FOR OZONE CLEANING SYSTEM - A method of making an aqueous ozone solution for an industrial cleaning system is described. The method includes providing a reaction vessel for entraining ozone gas in an aqueous solution. The reaction vessel includes a conical-shaped surface having a two or more edges or ridges. The conical-shaped surface defines an interior, and two or more edges or ridges are in contact with the interior. The reaction vessel is in fluidic communication with a supply of water. The reaction vessel is in fluidic communication with a supply of a first aqueous ozone solution. The first aqueous ozone solution is directed to the conical-shaped surface. Water is directed to the conical-shaped surface, and the water and the first aqueous ozone solution are mixed to form a second aqueous ozone solution. Compositions for aqueous ozone solutions are also described. | 2012-06-07 |
20120142576 | FAST DISSOLVING SOLID DETERGENT - A solid block or unit dosed detergent composition as described which can be utilized in a variety of applications for cleaning surfaces and objects, removing suspending soils, and rinsing easily. The detergent composition, when exposed to an aqueous solution such as water, dissolves quickly and completely to create the use solution. | 2012-06-07 |
20120142577 | Biodegradable Amphoteric Surfactants Based on C6 to C11 Linear or Predominately Linear Alcohols - A biodegradable amphoteric surfactant is disclosed. The surfactant, has excellent coupling efficiency, low to moderate foam, and good detergency. Amphoteric surfactants based on linear alkyl radicals or predominately linear alkyl radicals (R) of 6 to 11 carbons, and mixtures thereof are also disclosed. | 2012-06-07 |
20120142578 | FABRIC CARE COMPOSITION - The instant disclosure relates to compositions comprising glycerol esters. Methods of making and using such compositions are also disclosed. | 2012-06-07 |
20120142579 | METHOD OF MAKING A FABRIC CARE COMPOSITION - The instant disclosure relates to methods of making compositions comprising glycerol esters and a fabric softening active. Methods of using such compositions are also disclosed. | 2012-06-07 |
20120142581 | Polymer Formulations for Delivery of Bioactive Materials - PLGA, PLA and PGA polymers which have crystallinity resulting from the presence of long chain alkyl groups in terminal units. The polymers are particularly useful for drug delivery. | 2012-06-07 |
20120142582 | Combination of Dopamine Agonists Plus First Phase Secretagogues for the Treatment of Metabolic Disorders - The present invention is directed to a method of treating a metabolic disorder or key elements of a metabolic disorder such method comprising the use of an agent(s) that increases central dopaminergic activity plus a first-phase insulin secretagouge. | 2012-06-07 |
20120142583 | Methods of inhibiting and treating bacterial biofilms by metal chelators - The invention presented herein provides methods and compositions for the prevention and treatment of bacterial infections. The methods are based on the discovery that depletion of bioavailable iron stimulates surface motility in bacteria thus inhibiting the ability of a bacterial population to develop into a biofilm. | 2012-06-07 |
20120142584 | NOVEL TRANSPORTER CONSTRUCTS AND TRANSPORTER CARGO CONJUGATE MOLECULES - The present invention relates to novel transporter constructs of the generic formula (I) D | 2012-06-07 |
20120142585 | LEPTIN ANTAGONIST AND METHODS OF USE - This invention provides compounds that are true antagonists of the leptin receptor, in the presence and the absence of native leptin or another leptin receptor binder. These compounds may be used to inhibit leptin receptor activity, promote growth arrest or death of leptin receptor-positive cancer cells, or monitor or detect a leptin receptor-positive cell, in vitro or in vivo. These compounds may also be used to treat a weight-loss nutritional disorder, osteoporosis, rheumatoid arthritis, osteoarthritis, or inflammatory bowel disease. Also included in the invention are methods for detecting leptin receptor-positive cells, for arresting cell growth or killing cancer cells in vivo, for monitoring or detecting a leptin receptor-positive cell in vitro or in vivo, for treating a weight-loss nutritional disorder, for treating osteoporosis, for treating rheumatoid arthritis, for treating osteoarthritis, or for treating inflammatory bowel disease. | 2012-06-07 |
20120142586 | TREATMENT FOR OBESITY - The present invention provides peptides and pharmaceutical compositions thereof for appetite suppression and weight control. Preferred peptides are calcitonin analogs, preferably with specific amino acid changes to make the peptide more amylin-like. | 2012-06-07 |
20120142587 | LIQUID ENTERAL NUTRITIONAL COMPOSITION WITH A LOW MONOVALENT METAL ION CONTENT - Heat-treated liquid enteral nutritional composition with a low monovalent metal ion content are provided that contain micellar casein and optionally caseinate, and in which the total amount of monovalent metal ions is less than 25 mg/g of protein. Also, heat-treated liquid enteral nutritional compositions are disclosed comprising 10 to 20 g of protein per 100 ml of the composition, in which all or a major part of said protein comprises micellar casein. Also, a method is disclosed for producing the composition according to the invention, comprising a step wherein an aqueous protein solution in which all or a major part of said protein comprises micellar casein, is subjected to an evaporation step. | 2012-06-07 |
20120142588 | HSP THERAPY IN CONJUNCTION WITH A LOW ANTIGENICITY DIET - The present invention relates to a method for suppression, prevention, delaying the onset or treatment of diabetes, by administering to an individual in need thereof a fragment of Hsp60 or analog thereof in conjunction with a low antigenicity diet. The invention is exemplified using DiaPep277™, an analog of residues 437-460 of human Hsp60 in combination with a hydrolyzed casein diet. | 2012-06-07 |
20120142589 | TISSUE-PROTECTIVE CYTOKINES FOR THE PROTECTION, RESTORATION AND ENHANCEMENT OF RESPONSIVE CELLS, TISSUES AND ORGANS - Methods and compositions are provided for protecting or enhancing a responsive cell, tissue, organ or body part function or viability in vivo, in situ or ex vivo in mammals, including human beings, by systemic or local administration of a tissue protective cytokine. | 2012-06-07 |
20120142590 | Methods and Compounds Regulating the Erythroid Response to Iron Deficiency - The present invention discloses the signaling pathway involved in erythroid repression by iron deficiency. Further disclosed is a non-toxic small-molecule compound which potently reverses the erythroid repression caused by iron deficiency. The present invention further encompasses novel compounds for inhibition of red cell production, useful, for example, in the treatment of polycythemia vera, a malignancy causing uncontrolled red cell production. These inhibitory compounds also promote megakaryocytic lineage commitment and may therefore be useful for augmentation of platelet production. The present invention further discloses isocitrate reversal of iron deprivation. | 2012-06-07 |
20120142591 | METHOD OF TREATING INTRAOCCULAR TISSUE PATHOLOGIES WITH NERVE GROWTH FACTOR - Nerve Growth Factor (NGF), in the form of a preparation to be administered over ocular surface, is suggested as being suitable for therapy and/or prophylaxis of intraocular tissue pathologies, with particular reference to sclera, ciliary body, crystalline lens, retina, optic nerve, vitreous body and choroidea affections. When administered in the form of external ophthlamic preparation, for example as collyrium or ointment, NGF is capable to go through ocular tissues and it has been found out that it shows a therapeutic activity not only against retina and optic nerve pathologies but also against affections involving the above reported internal structures of the eye. | 2012-06-07 |
20120142592 | NASAL CALCITONIN FORMULATIONS CONTAINING CHLOROBUTANOL - An aqueous solution of calcitonin suitable for intranasal administration comprised of calcitonin, chlorobutanol at a concentration of less than 0.4% weight/weight, and water and having a pH of less than 4 with the proviso that benzalkonium chloride is not present in the solution. The aqueous solution of calcitonin can be used to treat osteoporosis, Paget's bone disease and hypercalcemia. | 2012-06-07 |
20120142593 | Factor VIII Variants and Methods of Use - A Factor VIII fusion protein or a Factor VIII fusion heterodimer comprising Factor VIII in which an amino acid sequence of a modulator is present in the B-domain, or an amino acid sequence of a modulator replaces some or all of the amino acid sequence of the B-domain is disclosed. Nucleic acids encoding the inventive fusion proteins and fusion heterodimers are also disclosed, as are methods for producing the fusion proteins and fusion heterodimers, pharmaceutical compositions, and methods of treating deficiencies in coagulation with the inventive fusion molecules. | 2012-06-07 |
20120142594 | Von Willebrand Factor- and Factor VIII-Polymer Conjugates Having a Releasable Linkage - The present invention provides von Willebrand Factor-polymer conjugates and Factor VIII-polymer conjugates, each having a releasable linkage. Methods of making conjugates, methods for administering conjugates, are also provided. | 2012-06-07 |
20120142595 | TISSUE PROTECTIVE PEPTIDES AND USES THEREOF - Provided herein are tissue protective peptides derived from or sharing consensus sequences with portions of cytokine receptor ligands, including Erythropoietin (EPO), that are generally located on or within the region of the cytokine receptor ligand that faces away from a receptor complex while the ligand is bound to the receptor. Also provide herein are fragments, chimeras, as well as peptides designed to mimic the spatial localization of key amino acid residues within the tissue protective receptor ligands, e.g., EPO; methods for treating or preventing a disease or disorder using tissue protective peptides; and methods for enhancing excitable tissue function using tissue protective peptides. | 2012-06-07 |
20120142596 | AGENT FOR STIMULATING MOBILIZATION OF ENDOTHELIAL PROGENITOR CELLS - The present invention provides a composition for stimulating the mobilization of endothelial precursor cells, which comprises substance-P (SP). Substance-P according to the invention exhibits an activity of stimulating the mobilization of endothelial precursor cells from the bone marrow, thereby stimulating vasculogenesis. Thus, substance-P exhibits excellent effects on the prevention or treatment of diseases, including myocardial infarction, angina, ischemic stroke, cerebrovascular dementia, cerebral infarction, sequelae of cerebral injury, spinal cord injury, sequelae of spinal nerve injury, degenerative diseases, sequelae of cerebral infarction, peripheral nerve disorders, presbyopia, degenerative hearing loss, sequelae of brain surgery, and diabetic ulcer, which are accompanied by ischemic vascular injury or traumatic vascular injury. | 2012-06-07 |
20120142597 | BIOMOLECULAR COATING FOR IMPLANTS - Methods and compositions are provided for improving tissue growth and device integration in vivo. Substrates and devices coated with an α | 2012-06-07 |
20120142598 | EDIBLE COMPOSITIONS FOR PREVENTING HAIR LOSS - The present invention provides compositions comprising hydrolyzed gelatin or a mixture of hydrolyzed gelatin and gelatin, and the same compositions for use in methods comprising administering a low dose of the compositions useful in prophylaxis and treatment of hair loss in humans and shedding in animals. The compositions provide a palatable, malleable and well-tolerated product. | 2012-06-07 |
20120142599 | EXTRACT OF R. MIEHEI - Topical compositions comprising extracts of | 2012-06-07 |
20120142600 | Analogs of ShK Toxin and their Uses in Selective Inhibition of Kv1.3 Potassium Channels - Analogs of ShK toxin and methods for using such ShK analogs. The ShK analogs generally comprise ShK toxin attached to a chemical entity (e.g. an atom, molecule, group, residue, compound, moiety, etc.) that has an anionic charge. The ShK analogs may be administered to human or non-human animal subjects to cause inhibition of potassium channels or to otherwise treat diseases or disorders. In some embodiments, the chemical entity to which the ShK toxin is attached may be chosen to provide selective inhibition of certain potassium channels (e.g., Kv1.3 channels) over other potassium channels (e.g., Kv1.1 channels). In come embodiments, the chemical entity to which the ShK toxin is attached may include a fluorophore and such fluorophore-tagged ShK analogs may be used in flow cytometry alone, or in conjunction with class II tetramers that can detect autoreactive cells. | 2012-06-07 |
20120142601 | Modified Peptides and Uses Thereof - The invention includes compounds that are useful in treating perioperative shivering or temperature spiking, lowering body temperature, treating psychosis or treating pain. The invention also includes methods for treating perioperative shivering or temperature spiking, lowering body temperature, treating psychosis or treating pain in a subject in need thereof. | 2012-06-07 |
20120142602 | Composition and Method for Preventing or Treating a Tauopathy - The present invention is a composition and method for the prevention and treatment of a tauopathy. The composition of the invention includes N-terminal amino acid residues of the tau protein, which have been identified as being involved in toxic activation of a PP1/GSK3 signaling cascade and inhibition of fast axonal transport in human tauopathies. | 2012-06-07 |
20120142603 | BIOADHESIVE PATCH FOR SUTURELESS CLOSURE OF SOFT TISSUE - Provided herein are compositions and methods for treating soft tissue injuries using a patch having a polymer on its surface linked to polypeptides having a disintegrin domain. The polypeptides having a disintegrin domain can include contortrostatin, vicrostatin, and ADAM derived polypeptides. Compositions of the invention can be used for the treatment of injuries to soft tissues that include the eye, liver and brain. | 2012-06-07 |
20120142604 | NOVEL APPLICATIONS OF HIP/PAP OR DERIVATIVES THEREOF - The use of the HIP/PAP protein or a protein derivative thereof for manufacturing a medicament for preventing or treating:
| 2012-06-07 |
20120142605 | METHODS OF TREATING PSORIASIS - The invention includes methods for treating patients having psoriasis and methods for testing the efficacy of such treatments. The methods include treating the patients with a TNF inhibitor plus a topical preparation containing a glucocorticoid. | 2012-06-07 |