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23rd week of 2009 patent applcation highlights part 43
Patent application numberTitlePublished
20090143209Flexible roller assembly - A compliant roller assembly comprising an elastomeric tube for rolling along a surface, which tube is inherently compliant to irregularities in the surface. Within the tube but smaller than the inner diameter thereof is a core apparatus comprising a non-rotating mounting element supportive of a plurality of idle rollers, extending from the mounting element in the direction of tube travel, the idle rollers making contact with the inner wall of the tube, preferably at a line orthogonal to the contact line of the tube with the surface being rolled. In a preferred embodiment, the core apparatus exerts no force vector toward the surface being rolled, the weight of the elastomeric tube itself exerting sufficient force.2009-06-04
20090143210Parallel folding apparatus of folding machine - A parallel folding apparatus of a folding machine, which can automatically exercise position control of brush guides in accordance with folding specifications while the machine is in operation, is provided. In the parallel folding apparatus of the folding machine, comprising: 2009-06-04
20090143211SYSTEMS AND METHODS FOR CARBON CAPTURE AND SEQUESTRATION AND COMPOSITIONS DERIVED THEREFROM - A method of sequestering a greenhouse gas is described, which comprises: (i) providing a solution carrying a first reagent that is capable of reacting with a greenhouse gas; (ii) contacting the solution with a greenhouse gas under conditions that promote a reaction between the at least first reagent and the greenhouse gas to produce at least a first reactant; (iii) providing a porous matrix having interstitial spaces and comprising at least a second reactant; (iv) allowing a solution carrying the at least first reactant to infiltrate at least a substantial portion of the interstitial spaces of the porous matrix under conditions that promote a reaction between the at least first reactant and the at least second reactant to provide at least a first product; and (v) allowing the at least first product to form and fill at least a portion of the interior spaces of the porous matrix, thereby sequestering a greenhouse gas.2009-06-04
20090143212HIGH-STRENGTH HEAVY-METAL OXIDE GLASS FIBERS AND PROCESS OF MAKING - An optical fiber according to Tran U.S. Pat. No. 5,274,728 is improved by chemically etching the surface of the GeO2009-06-04
20090143213LOW EXPANSION GLASS MATERIAL HAVING LOW EXPANSIVITY GRADIENT - A low expansion glass substrate includes titania and silica and has a thermal expansivity with an average gradient less than 1 ppb/° C./° C. in a temperature range of 19° C. to 25° C.2009-06-04
20090143214Glass composition - A glass composition which is reduced in the amount of residual bubbles and is produced using smaller amounts of an environmentally unfriendly component such as arsenic oxide and antimony oxide. This glass composition comprises, in terms of mass %: 40-70% SiO2009-06-04
20090143215PROCESS FOR REDUCING NON-UNIFORMITIES IN THE DENSITY OF SINTERED MATERIALS - There is disclosed a pre-sintering process for reducing non-uniformities in the density of a sintered material comprising (a) providing a mixture of (i) a first sinterable material containing a contaminant the presence of which during sintering of the first sinterable material results in a higher vapor pressure than would occur during sintering of pure first sinterable material and (ii) a second material having a higher affinity for the contaminant than does the first sinterable material; and (b) heating the mixture at a temperature and for a time sufficient to allow the second material to at least partly mitigate the propensity of the contaminant to raise the vapor pressure during the sintering of the first sinterable material. Other embodiments are also disclosed.2009-06-04
20090143216COMPOSITION AND METHOD - A composition includes a sintered mass having a plurality of cores and a grain boundary layer disposed between each of the plurality of cores. The core includes a transition metal oxide, and grain boundary layer includes a sintering additive, a grain growth inhibitor additive and a grain boundary additive.2009-06-04
20090143217ALUMINA-SILICA-BASED FIBER, CERAMIC FIBER, CERAMIC FIBER COMPLEX, RETAINING SEAL MATERIAL, PRODUCTION METHOD THEREOF, AND ALUMINA FIBER COMPLEX PRODUCTION METHOD - A manufacturing method by which alumina-silica based fibers excellent in mechanical strength can be readily and securely obtained. The method obtains precursor fibers as a material by using an alumina-silica based fiber spinning stock solution for use in an inorganic salt method. Next, the precursor fibers are heated under an environment which makes it difficult to carry out an oxidizing reaction on the carbon component contained in the precursor fibers. Thus, the precursor fibers are sintered to obtain alumina-silica based fibers.2009-06-04
20090143218REGENERATION PROCESS FOR A C8 ALKYLAROMATIC ISOMERIZATION CATALYST - One exemplary embodiment can be a regeneration process for a C8 alkylaromatic isomerization catalyst. The process can include:2009-06-04
20090143219Stabilizers for ceramic body extrusion - A mixture for making a ceramic article includes a ceramic forming component, a liquid vehicle, a cellulosic binder, and a stabilizer comprising an acetate salt. The disclosure also provides a method of making the ceramic article including extruding the mixture to form a ceramic green body, drying the ceramic green body to remove at least a portion of the liquid vehicle, and optionally firing to form the ceramic article. The ceramic green body possesses excellent strength and excellent skin properties without increasing the organic load or the addition of hydrated clays.2009-06-04
20090143220PROCESS FOR THE PRODUCTION OF HYBRID CATALYSTS FOR FISCHER-TROPSCH SYNTHESIS AND HYBRID CATALYST PRODUCED ACCORDING TO SAID PROCESS - Process for the production of hybrid catalysts formed by mixing two catalysts; one active in Fischer-Tropsch synthesis, the other being bifunctional. Such hybrid catalyst thus formed is active both in hydrocracking and in hydroisomerisation reactions. The present invention in addition provides obtainment of a hybrid catalyst and application thereof conjointly with FT catalysts in Fischer-Tropsch synthesis reactions. The hybrid catalyst of the present invention is capable of producing in conditions typically such as those utilised in Fischer-Tropsch synthesis branched hydrocarbons in diverse bands relating to the products thereof (for example naphtha and diesel), reducing or even eliminating necessity for a subsequent hydrotreatment stage in such synthesis reactions. Utilisation of such hybrid catalysts of the present invention prolongs the operational efficiency and working life of conventional Fischer-Tropsch synthesis catalysts, reducing substantially encapsulation of particles thereof by waxes produced in the hydroprocessing reactions.2009-06-04
20090143221Zeolite-Based Honeycomb Body - Zeolite-based honeycomb bodies and methods of manufacturing same. Zeolite-based honeycomb bodies especially suited for engine exhaust treatment applications include a primary phase comprising a zeolite having a SiO2 to Al2O3 molar ratio in the range from 5 to 300. The zeolite-based composites are porous with an open porosity of at least 25% and a median pore diameter of at least 1 micron. The zeolite-based honeycomb bodies can be manufactured by an extrusion method.2009-06-04
20090143222METHODS OF USING HETEROCYCLE-AMINE LIGANDS, COMPOSITIONS, COMPLEXES, AND CATALYSTS - Ligands, compositions, and metal-ligand complexes that incorporate heterocycle-amine compounds are disclosed that are useful in the catalysis of transformations such as the polymerization of monomers into polymers. The catalyst have high performance characteristics, including higher comonomer incorporation into ethylene/olefin copolymers, where such olefins are for example, 1-octene, propylene or styrene. The catalysts also polymerize propylene to form isotactic polypropylene.2009-06-04
20090143223Catalyst for the Recombination of Hydrogen with Oxygen - Large quantities of explosive hydrogen-oxygen mixtures can be produced by leaks or accidents in technical plants, e.g. nuclear reactors. The invention relates to a catalyst, a catalyst system, an arrangement for recombining hydrogen with oxygen, and a method for producing a catalyst. The inventive catalyst is characterized in that the ignition point of the mixture is exceeded under no circumstances even though the catalyst works in a strictly passive manner without outside intervention and the recombination is an exothermal reaction. The basic idea is to design the catalyst such that the catalyst autonomously limits the activity thereof in accordance with the prevailing temperature.2009-06-04
20090143224PROCESS FOR PREPARING A REFORMING CATALYST COMPRISING A SUPPORT, A GROUP VIIIB METAL AND A GROUP VIIB METAL - For preparing a reforming catalyst comprising a support, a group VIIIB metal and a group VIIB metal, comprises the following steps in the order a) then b) or b) then a): 2009-06-04
20090143225SCR CATALYST FOR REMOVAL OF NITROGEN OXIDES - The present invention provides for catalysts for selective catalytic reduction of nitrogen oxides. The catalysts comprise metal oxide supporters, vanadium, an active material, and antimony, a promoter that acts as a catalyst for reduction of nitrogen oxides, and at the same time, can promote higher sulfur poisoning resistance and low temperature catalytic activity. The amount of antimony of the catalysts is preferably 0.5-7 wt %.2009-06-04
20090143226Adsorbents for Advanced Glycation End products - The object of the present invention is to provide an adsorbent having an excellent AGEs adsorption ability. The present invention provides an adsorbent for advanced glycation end products consists of a copolymer resin having hydrophilic methacrylate, wherein the constituent unit of said copolymer resin consists of a particular methacrylate compounds and vinyl compounds. Preferably, the copolymer resin having hydrophilic methacrylate has one or more basic ion-exchange groups.2009-06-04
20090143227POROUS SUBSTRATES, ARTICLES, SYSTEMS AND COMPOSITIONS COMPRISING NANOFIBERS AND METHODS OF THEIR USE AND PRODUCTION - Porous and/or curved nanofiber bearing substrate materials are provided having enhanced surface area for a variety of applications including as electrical substrates, semipermeable membranes and barriers, structural lattices for tissue culturing and for composite materials, production of long unbranched nanofibers, and the like.2009-06-04
20090143228Dioxazine-and Oxadiazine-Substitude Arylamide - Novel dioxazine- and oxdiazine-substituted arylamides of the formula (I)2009-06-04
20090143229SYNTHESIS AND HERBICIDAL ACTIVITY OF 1- (2-SUBSTITUTED BENZO[d]THIAZOL-5-YL)- 1H-1,2,4-TRIAZOL-5(4H)- ONE DERIVATIVES - Synthesis and herbicidal activity of novel 1-(2-substituted benzo[d]thiazol-5-yl)-1H-1,2,4-triazol-5(4H)-one derivatives. Using a dose of 300 gai./h, the compounds of the invention possess significant herbicidal activity for 2009-06-04
20090143230INHIBITION OF BIOFILMS IN PLANTS WITH IMIDAZOLE DERIVATIVES - Disclosure is provided for methods of preventing, removing or inhibiting microbial biofilm formation or microbial infection in a plant or plant part thereof, including applying thereto a treatment effective amount of an active compound as described herein, or an agriculturally acceptable salt thereof. Methods of enhancing a microbicide (e.g., including a copper, antibiotic, bacteriophage, etc.) and/or plant defense activator are also provided, including applying an active compound as described herein. Compositions comprising an active compound as described herein in an agriculturally acceptable carrier are also provided, and in some embodiments the compositions further include a microbicide (e.g., including copper, antibiotic, bacteriophage, etc.) and/or plant defense activator.2009-06-04
20090143231Method For Enhancing the Quality of Green Leaf Vegetables - The present invention relates, inter alia, to a method for producing a green leaf vegetable having an extended shelf life or enhanced organoleptic properties, or both, which comprises applying to the foliage of a green leaf vegetable during its growing period an effective amount of a strobilurin or strobilurin-type fungicide. In particular, the present invention relates to a method for producing lettuce having an extended shelf life or enhanced organoleptic properties.2009-06-04
20090143232METHOD FOR SYNTHESISING TEMPLATED MOLECULES - The invention relates to a method for synthesizing templated molecules attached to the templated which directed the synthesis thereof. The method involves a template, a scaffold functional entity and a functional entity attached to a building block, which, in turn, is attached the template. The scaffold functional entity and the functional entity of the building block are both provided with complementary dimerization domains allowing the functional entities to come into close proximity when the complementary domains interact with to each other. The method may be used for generating libraries of templated molecules which may be selected for biological activity.2009-06-04
20090143233DEVICE AND METHOD FOR DIGITAL MULTIPLEX PCR ASSAYS - A method and device for digital multiplex PCR assays employ a microfluidic chip for performing real-time, continuous flow PCR within microchannels of the chip. A stream of sample material is introduced into each microchannel and alternating boluses of assay-specific reagents and buffer are introduced into the stream to form sequentially configured test boluses. A PCR procedure is performed on the test boluses followed by a thermal melt procedure. During the thermal melt procedure, fluorescent output is detected and fluorescence vs temperature data is collected and compared to expected normal correlations. The results, positive or negative, are converted to digital format, with positive results designated as “1” and negative results designated as “0”, or vice versa.2009-06-04
20090143234QUALITY CONTROL METHODS FOR ARRAYED OLIGONUCLEOTIDES - We disclose quality controls methods that allow quick and accurate verification of a test oligonucleotide deposited on a solid support. It is especially useful for the verification of oligonucleotides representing alleles of a multi-allelic locus. It employs single base extension, with labeled dideoxynucleotides, to locate and verify the identity of test oligonucleotides. This approach involves synthesizing a complement probe oligonucleotide for each oligonucleotide being tested. Probe oligonucleotides are optionally grouped. They are then hybridized to test oligonucleotides, and the hybridized pair is subject to single base extension and detection. It requires the presence of one unique base, either in the last two bases at the free hanging end of the test oligonucleotide—as opposed to the end anchored to the solid support surface, or in the last two bases at one end of the probe oligonucleotide.2009-06-04
20090143235EFFICIENT ARRAYS OF AMPLIFIED POLYNUCLEOTIDES - The present invention is related generally to analysis of polynucleotides, particularly polynucleotides derived from genomic DNA. The invention provides methods, compositions and systems for such analysis. Encompassed by the invention are arrays of polynucleotides in which the polynucleotides have undergone multiple rounds of amplification in order to increase the strength of signals associated with single polynucleotide molecules.2009-06-04
20090143236Method of detecting cancer cell acquiring drug-resistance - It is an object of the present invention to find out a novel gene marker by which a drug-resistant cancer cell can be detected and provide a means of efficiently and comprehensively detecting a drug-resistant cancer cell using this marker. In the present invention, gene amplifications or deletions have been analyzed in cancer cell strains resistant to drugs, which are anticancer drugs having particularly serious side effects and being administered to cancer patients at a high frequency (namely, camptothecins, cisplatins, etoposides, adriamycins (ADM), and cytosine arabinosides), and parent cancer cell strains. As a result, it was found out that the acquisition of drug-resistance to an anticancer drug in a test cancer cell can be detected by detecting amplification of one or more genes selected from ABC transporter genes and BCL2 family genes consisting of ABCA3 gene, ABCB6 gene, ABCB8 gene, ABCB10 gene, ABCC4 gene, ABCC9 gene, ABCD3 gene, ABCD4 gene, ABCE1 gene, ABCF2 gene, BCL2L2, BCL2L10, BCL2L1, and BCL2A1 which are novel gene markers relating to the acquisition of drug resistance of cancer cells.2009-06-04
20090143237Methods, kits and compositions pertaining to fluorescence quenching using pna probes - Disclosed for instance, are methods suitable for the detection, identification and/or quantitation of nucleic acid target sequences using probes. Suitable probes include those consisting of peptide nucleic acid (PNA) or locked nucleic add (LNA) units. Binding of the probes to adjacent target sequences results in fluorescent quenching. Analysis of changes in the fluorescent signal is used to detect, identify or quantitate a target sequence in a sample. The invention is more specifically directed to methods for improving the sensitivity, specificity and/or reliability of diagnostic tests using suitable probes. It is particularly well-suited for real-time PCR and related amplification reaction.2009-06-04
20090143238Oligonucleotide matrix and methods of use - The present invention relates broadly to compositions and methods for performing nucleic acid analysis. In particular the invention relates to a universal oligonucleotide probe set and a hybridization matrix or array for performing analysis of nucleic acids from any source. The oligonucleotide matrix of the present invention provides up to approximately 102009-06-04
20090143239FLUORESCENCE BASED BIOSENSOR - A novel biosensor comprises at least one fluorophore and at least two quenchers, and is capable of selectively and specifically detecting the presence of an ion in the presence of other ions.2009-06-04
20090143240Novel Methods for Genome-Wide Location Analysis - The invention relates to improved methods of identifying the genomic regions to which a protein of interest binds, and in particular, to methods that use tiled arrays. The invention also provides methods of identifying the transcriptional rate of the gene in a cell. The invention also relates to methods of performing genome-wide location analysis, and ChIP-CHIP analysis, using histones and modified histones.2009-06-04
20090143241ANTIBACTERIAL AND PLASMID ELIMINATION AGENTS - Inhibitors of the tmRNA pathway have antibacterial activity with broad species specificity, including 2009-06-04
20090143242ALIEN SEQUENCES - The present invention provides sequences and reagents for preparing microarrays with internal controls. Specifically, the present invention defines and provides sequences that are not present in the hybridizing mRNA or cDNA, and therefore can be used both as hybridization controls and for inter-spot normalization.2009-06-04
20090143243MICROARRAY SYSTEM WITH IMPROVED SEQUENCE SPECIFICITY - The invention provides a novel array method for nucleic acid sequence detection with improved specificity which allows for detection of genetic variation, from simple SNPs (where the variation occurs at a fixed position and is of limited allelic number) to more complex sequence variation patterns (such as with multigene families or multiple genetic strains of an organism where the sequence variation between the individual members is neither fixed nor consistent). The array is comprised of short, synthetic oligonucleotide probes attached to a solid surface which are hybridized to single-stranded targets. Single stranded targets can be produced using a method that employs primers modified on the 5′ end to prohibit degradation by a 5′-exonuclease that is introduced to degrade the unprotected strand. The invention further provides for printing buffers/solutions for the immobilization of oligonucleotide probes to an array surface. The invention also provides hybridization and wash buffers and conditions to maximize hybridization specificity and signal intensity, and reduce hybridization times.2009-06-04
20090143244System and apparatus for sequential processing of analytes - An apparatus and system are provided for simultaneously analyzing a plurality of analytes anchored to microparticles. Microparticles each having a uniform population of a single kind of analyte attached are disposed as a substantially immobilized planar array inside of a flow chamber where steps of an analytical process are carried out by delivering a sequence of processing reagents to the microparticles by a fluidic system under microprocessor control. In response to such process steps, an optical signal is generated at the surface of each microparticle which is characteristic of the interaction between the analyte carried by the microparticle and the delivered processing reagent. The plurality of analytes are simultaneously analyzed by collecting and recording images of the optical signals generated by all the microparticles in the planar array. A key feature of the invention is the correlation of the sequence of optical signals generated by each microparticle in the planar array during the analytical process.2009-06-04
20090143245MICROARRAYS FOR GENOTYPING AND METHODS OF USE - The present invention provides a microarray for detecting a genotype at a polymorphic site in a plurality of nucleic acid samples, comprising a first set of nucleic acid fragments derived from the samples and a second set of nucleic acid fragments derived from a plurality of references immobilized thereon. The invention also provides a microarray comprising a set of nucleic acid fragments immobilized on the surface of the microarray, wherein the nucleic acid fragments are derived from the samples by amplifying a region in the sample containing the polymorphism through asymmetric PCR amplification. Methods of using and making the microarrays are also provided.2009-06-04
20090143246Patterning with compositions comprising lipid - Better patterning methods, including for better methods for forming biomolecular arrays, including a method comprising: providing a tip and a substrate surface, disposing a patterning composition at the end of the tip, depositing at least some of the patterning composition from the tip to the substrate surface to form a deposit disposed on the substrate surface, wherein the patterning composition comprises at least one lipid, optionally at least one solvent, and at least one patterning species different from the lipid and the optional solvent. The lipid can be a phospholipid such as DOPC. The patterning species can be an oligonucleotide or a protein. Microarrays and nanoarrays can be prepared including nanoscale resolution of deposits. The lipid can activate patterning or increase the rate of patterning. Simplified tip preparation can be achieved. Nanoscopic, SPM, and AFM tips can be used.2009-06-04
20090143247Methods for Producing Active scFv Antibodies and Libraries Therefor - The present disclosure describes scFv antibody libraries, antibodies isolated from the libraries, and methods of producing and using the same.2009-06-04
20090143248Biologically active C-terminal arginine-containing peptides - The present invention concerns the separation, identification and characterization of active peptide fragments from peptones.2009-06-04
20090143249BIOARRAY CHIP REACTION APPARATUS AND ITS MANUFACTURE2009-06-04
20090143250MICROFLUIDIC DEVICE USING MICROFLUIDIC CHIP AND MICROFLUIDIC DEVICE USING BIOMOLECULE MICROARRAY CHIP - Disclosed is a microfluidic device including a microfluidic structure formed in a platform in which various examinations, such as an immune serum examination, can be automatically performed using the biomolecule microarray chip. The biomolecule microarray chip-type microfluidic device using a biomolecule microarray chip comprises: a platform which is rotatable; a microfluidic structure disposed in the platform, comprising: a plurality of chambers; a plurality of channels connecting the chambers each other; and a plurality of valves controlling flow of fluids through the channels, wherein the microfluidic structure controls flow of a fluid sample using rotation of the platform and the valves; and a biomolecule microarray chip mounted in the platform such that biomolecule capture probes bound to the biomolecule microarray chip contact the fluid sample in the microfluidic structure.2009-06-04
20090143251APPARATUS FOR PRODUCING PROBE CARRIER - An apparatus for producing a probe carrier in which ambient humidity for a plurality of nozzles of a liquid ejection device for ejecting droplets of solutions containing probes to the surface of a carrier is controlled to 50% or more, preferably 60% or more. A part of solution supply passages to the plurality of nozzles is constructed from gas permeable membranes permitting gas-liquid separation under reduced pressure. These gas permeable membrane portions are gathered and altogether placed under reduced pressure to remove air bubbles from the respective solutions supplied to the plural nozzles and decrease the amount of a dissolved gas, which causes air bubbles to be generated.2009-06-04
20090143252Dispersing Sulfide Scales in Oil and Gas Production Systems - A homopolymer of a monomer selected from those having the general formula:2009-06-04
20090143253Drilling fluids containing microbubbles - A drilling fluid comprises water and microbubbles in an amount to achieve a density of the fluid in the range of 4-6 pounds per gallon; the desired density is achieved, and the novel drilling fluid exists, at pressures in the range of 350-5000 pounds per square inch.2009-06-04
20090143254Glycerol Based Drilling Fluids - The present invention relates to glycerol based drilling fluids. In particular, the invention relates to drilling fluids comprising a 95-20 volume % glycerol/water solution capable of stabilizing water-sensitive formations during drilling and the use of such solutions for drilling a well having water-sensitive formations.2009-06-04
20090143255Methods and Compositions for Improving Well Bore Stability in Subterranean Formations - Films that may be created and/or placed in a well bore that prevent the flow of fluid into cracks or fractures in a portion of a subterranean formation penetrated by the well bore, and associated methods of use, are provided. In one embodiment, the methods comprise: providing a treatment fluid that comprises a base fluid and a film-forming polymer; introducing the treatment fluid into a portion of a well bore penetrating a portion of a subterranean formation, the well bore comprising an interior wall; and allowing the film-forming polymer to electrostatically interact with a surface of the interior wall of the well bore to form a substantially continuous film along a portion of the interior wall of the well bore, the substantially continuous film being capable of hindering the flow of a fluid therethrough.2009-06-04
20090143256Utilization of surfactant as conformance materials - Methods for creating a fluid diverting barrier in a zone of a subterranean formation are provided. Certain methods comprise providing a treatment fluid that comprises an aqueous base fluid, a viscoelastic surfactant, and a soap component; placing the treatment fluid in a subterranean formation penetrated by a well bore; and allowing the soap component of the treatment fluid to interact with a metal ion present in the subterranean formation to form a precipitate.2009-06-04
20090143257Methods and Compositions for Controlling Water Production - A composition for treatment of a subterranean formation, which may be used for water control, is comprised of at least one of 1) a premix of an oleochemical polyol, at least one of polyisocyanate, polycyanate and polyisothiocyanate, and a blocking agent to temporarily block all or a portion of free reactive groups of said at least one of polyisocyanate, polycyanate and polyisothiocyanate. Alternatively, or in addition, the composition may be comprised of a solvent and 2) a polyurethane prepolymer formed by reacting an oleochemical polyol and at least one of polyisocyanate, polycyanate and polyisothiocyanate. A blocking agent may also be used with the polyurethane prepolymer. The composition may be used in a method of treating a subterranean formation penetrated by a wellbore by introducing the composition into the formation through the wellbore. In another embodiment, a method of treating a subterranean formation penetrated by a wellbore is carried out by forming a treatment fluid containing at least one of 1) palmitic acid or its derivatives and 2) palm oil and at least one of an hydrolyzing or oxidizing agent to facilitate formation of palmitic acid or its derivatives. The treatment fluid also includes a source of a monovalent ions. The treatment fluid is introduced into the wellbore for treatment of the subterranean formation.2009-06-04
20090143258Methods and compostions for preventing scale and diageneous reactions in subterranean formations - Methods and compositions useful to prevent scale formation and/or diageneous reactivity on mineral surfaces residing or to be placed in subterranean formations, are provided. In one embodiment, the methods comprise: providing an anionic polymer and a cationic surfactant; contacting a mineral surface with the anionic polymer and the cationic surfactant; and allowing the anionic polymer and the cationic surfactant to interact with each other, whereby a film is formed on at least a portion of the mineral surface.2009-06-04
20090143259Particles - Manufactures particles comprising a chemical treatment agent which are useful in wells are provided. The particles have the advantage of being able to chemically treat a well, e.g. to remove filter cake. Embodiments of the invention improve well production by providing sand control and/or increasing permeability of a gravel pack. Methods of using the particles and a gravel pack comprising the particles are also provided.2009-06-04
20090143260Methods and compositions relating to the reduction of volatile phosphorus from crude - This invention relates to methods and compositions useful in treating crude sources, and more specifically, to methods and compositions useful in reducing the concentration of phosphorus in crude streams and hydrocarbon flowback fluids. In some embodiments, the present invention provides methods that include a method comprising: providing a crude stream or a hydrocarbon flowback fluid; optionally testing the crude stream or the hydrocarbon flowback fluid for total phosphorus content; optionally testing the crude stream or hydrocarbon flowback fluid for volatile phosphorus content; adding a solution comprising a trivalent metal ion to the crude stream or the hydrocarbon flowback fluid; adding a sufficient amount of a caustic solution to the crude stream or the hydrocarbon flowback fluid to raise the pH of the stream or the fluid to about 8 or more; allowing at least a plurality of precipitates to form; removing at least one precipitate; and forming a clean crude stream or a clean hydrocarbon flowback fluid.2009-06-04
20090143261Engine Oil Compositions with Improved Fuel Economy Performance - An engine lubricating oil exhibiting a fuel economy improvement is disclosed. The engine oil composition meets at least one of ILSAC GF-4, API CI-4, API CJ4, ACEA A1, ACEA A5, ACEA B1, ACEA B5, ACEA C1, ACEA C2, ACEA C3, ACEA C4A, and JASO DL-1 performance specifications. The composition comprises at least an isomerized base oil comprising a consecutive number of carbon atoms and having a CCS Viscosity at −35° C. of less than or equal to 7000 mPa, a T2009-06-04
20090143262Lubricant Composition - A lubricant composition containing a polymer having a mesogen structure in a main chain and/or side chains thereof is disclosed.2009-06-04
20090143263LUBRICANT COMPOSITION COMPRISING A BI-MODAL SIDE-CHAIN DISTRIBUTION LOFI - A lubricant composition is disclosed. The lubricant composition is made up of (a) an API Group III base stock; (b) one or more semi-crystalline viscosity modifier; and (c) one or more LOFIs having a side-chain distribution which satisfies the following requirements: (1) the distribution contains side chains ranging from C2009-06-04
20090143264SULFURIZED METAL ALKYL PHENATE COMPOSITIONS HAVING A LOW ALKYL PHENOL CONTENT - Provided herein are sulfurized metal alkyl phenate compositions having a low alkyl phenol content. The sulfurized metal alkyl phenate compositions can be prepared by reacting a phenol compound of Formula (I) disclosed herein with an aldehyde to form a phenolic resin of Formula (II) disclosed herein and then by reacting the phenolic resin simultaneously with a metal base and a first sulfurizing agent. The sulfurized metal alkyl phenate compositions and the overbased sulfurized metal alkyl phenate compositions disclosed herein may be used as detergents for formulating lubricating oil compositions. The lubricating oil compositions disclosed herein have a reduced amount of the free phenol compound and a salt thereof.2009-06-04
20090143265ADDITIVES AND LUBRICANT FORMULATIONS FOR IMPROVED ANTIOXIDANT PROPERTIES - A lubricating oil composition, additive concentrate, method of lubricating moving parts, a method of improving the oxidation stability of a lubricant formulation. The lubricating oil composition includes a base oil, a hydrocarbon soluble molybdenum compound, and an antioxidant effective amount of one or more polymeric compounds devoid of ester linkages. The polymeric compound may be represented by of the formula:2009-06-04
20090143266DETERGENT COMPOSITION - A laundry additive composition comprising one or more perfume components in slow release form and wherein the release kinetics are controlled so as to provide a fabric delivery index of at least 0.3.2009-06-04
20090143267Packaging for high moisture bar soap - Packaging is provided for high moisture bar soap compositions to address a number of potential problems associated with high moisture bar soap compositions, such as minimizing moisture loss, inhibiting mold growth on paperboard material used in the packaging, and preventing the development of colored stains on the bar soap and packaging resulting from chemical reaction between the high moisture bar soap and the paperboard, especially recycled paperboard. The bar soap packaging comprises a laminate material comprising a paperboard material, a thermoplastic material disposed on at least one side of the paperboard material, and a fungicide. Further provided is a method of inhibiting the growth of mold on a paperboard package which can result from storage of a high moisture bar soap composition in the paperboard package by treating the paperboard package with a fungicide comprising chlorothalonil and p-tolyl diiodomethyl sulfone, and then packaging the high moisture bar soap composition in the treated paperboard package.2009-06-04
20090143268Method for Washing the Face Skin and a Composition for Carrying Out Said Method - The inventions relate to hygiene and cosmetology, in particular to skin care.2009-06-04
20090143269Detergent Composition - A detergent composition comprising: 2009-06-04
20090143270ALPHA-AMYLASE VARIANT WITH ALTERED PROPERTIES - The present invention relates to variants (mutants) of parent Termamyl-tike alpha-amylases, which variant has alpha-amylase activity and exhibits altered properties relative to the parent alpha-amylase.2009-06-04
20090143271Colour-protecting laundry detergent - Laundry detergents containing a hyperbranched polyesteramide to inhibit transfer of dye during the washing of colored textiles. Also, methods of washing dyed textiles in surfactant-containing aqueous solutions also containing a hyperbranched polyesteramide.2009-06-04
20090143272ORGANIC CATALYST WITH ENHANCED SOLUBILITY - This invention relates to organic catalysts comprising iminium or oxaziridinium moieties, cleaning compositions comprising such catalysts; and processes for making and using such catalysts and cleaning products.2009-06-04
20090143273Hard Surface Cleaning and Disinfecting Compositions - Hard surface cleaning and disinfecting compositions comprising cationic surfactants having germicidal properties, fluorosurfactant compounds, film-forming polymers and, optionally, detersive surfactants and or organic solvents. The hard surface cleaning and disinfecting compositions provide excellent cleaning and disinfection of hard surfaces.2009-06-04
20090143274Surfactant Reduction Enabled by Use of Isopropylnaphthalene Sulfonate Linker - Water-soluble salts of isopropylnaphthalene sulfonates function as a single linker in cleaning compositions, while maintaining cleaning performance as compared with reference formulations. A methodology is provided for reformulating detergent compositions with isopropylnaphthalene sulfonate linker. This allows for a reduction in other raw materials such as anionic and nonionic surfactants, without additional lipophilic or hydrophilic linker, providing cost savings and environmental benefit.2009-06-04
20090143275ADIPONECTIN RECEPTOR FRAGMENTS AND METHODS OF USE - Methods are disclosed of treating diabetes, abnormal adipocyte activity, and insulin resistance using C-terminal fragments of adiponectin receptor R1. Methods of causing the secretion of insulin in healthy and diabetic patients using C-terminal fragments of adiponectin receptor R1 are also disclosed. In addition, methods are disclosed of increasing the insulin levels in healthy patients using C-terminal fragments of adiponectin receptor R1. In addition, methods of treating abnormal adipocyte activity, treating metabolic syndrome, causing insulin secretion, increasing insulin levels, inhibiting insulin degradation enzyme, treating Alzheimer's disease, treating cardiovascular disease associated with adiponectin levels, inhibiting ADAM-17 enzyme, treating a condition associated with TNF-alpha, and treating a condition associated with HER2-neu are disclosed. Compositions, dosage forms, and kits are also disclosed.2009-06-04
20090143276Trimeric IL-1Ra - Interleuekin-1 receptor antagonists (IL-1Ra) including fusion proteins having a trimerizing domain and an IL-1Ra polypeptide sequence. The fusion proteins are part of trimeric complexes that are used in pharmaceutical compositions for treating diseases mediated by IL-1. Effective treatment of inflammatory diseases, such as rheumatoid arthritis and diabetes, are described.2009-06-04
20090143277NUTRITIONAL COMPOSITION FOR CONTROLLING BLOOD SUGAR LEVEL - A nutritional composition for controlling blood sugar level comprising a protein, a lipid and a carbohydrate, wherein energy percentages supplied by the protein, lipid and carbohydrate are 10 to 25%, 20 to 35% and 40 to 60%, respectively; and oleic acid in the lipid energy percentage is 60 to 90% and palatinose and/or trehalulose in the carbohydrate energy percentage is 60 to 100%.2009-06-04
20090143278PROCESS FOR PREPARING BIOACTIVE PROTEIN-ENRICHED WHEY PRODUCTS - The present invention involves the discovery that various liquid (whey) streams drained or expelled from cheese curd after salt addition in the preparation of cheese contain enriched levels of bioactive proteins such as lactoferrin, lactoperoxidase, immunoglobulins, and growth factors. According to the invention, these proteins may be further enriched through manipulation of the cheese salting process as described herein. The methods of the invention may be used to produce various whey products with enriched levels of all the above bioactive proteins present and, through manipulation of salting conditions, to enrich these proteins selectively.2009-06-04
20090143279Methods and compositions for treating metabolic disorders - The present invention provides methods of treating of disorders characterized by defective mitochondrial activity. In particular compounds of the present invention can be used in the treatment metabolic diseases and neurodegenerative diseases. The methods are also useful to increase oxidative phosphorylation or to decrease reactive oxygen species (ROS) production in a subject in need thereof.2009-06-04
20090143280ANTI-CANCER COMBINATION TREATMENT AND KIT-OF-PARTS - In one aspect the present invention relates to pharmaceutical kits of parts suitable for treating neoplastic diseases such as cancer comprising an anti-cancer medicament, a Basidiomycete bioactive agent in solid or liquid form, and, optionally instructions for a dosing regime.2009-06-04
20090143281THROMBOMODULIN ANALOGS FOR USE IN RECOVERY OF SPINAL CORD INJURY - The present invention relates to the use of thrombomodulin analogs for the treatment of trauma-induced spinal cord injury.2009-06-04
20090143282ENHANCED RECOVERY FOLLOWING OCULAR SURGERY - An ocular method comprising localized ocular administration of a pharmaceutically acceptable formulation and effective concentration of at least one neuro-stimulatory agent, which may include a macrolide, for a duration sufficient to at least partially restore corneal sensation, or at least one macrolide to reduce scarring after ocular surgery. The neuro-stimulatory agent may be one or more of a macrolide, macrolide analog, neurotrophin, or neuropoietic factor. The method is used in a patent following ocular surgery, such as vision-correction surgery, glaucoma surgery, or retinal detachment repair surgery.2009-06-04
20090143283Pituitary Adenylate Cyclase Activating Peptide (PACAP) Receptor (VPAC2) Agonists and Their Pharmacological Methods of Use - This invention provides novel peptides that function in vivo as agonists of the VPAC2 receptor. These insulin secretagogue polypeptides are shown to lower blood glucose in vivo more than controls upon glucose challenge. The polypeptides of this invention are also stable in formulation and have long half-lives. The peptides of the present invention provide a new therapy for patients with decreased endogenous insulin secretion, in particular type 2 diabetics. In particular, the invention is a polypeptide selected from a specific group of VPAC2-related polypeptides, or functional equivalents thereof. The invention is also directed to a method of treating a metabolic disease in a mammal comprising administering a therapeutically effective amount of the insulin secretagogue peptides to said mammal. Also disclosed are methods of making the peptides, both recombinant and synthetic.2009-06-04
20090143284Promoter of Regeneration of Pancreatic B Cell, and Promoter of Insulin Production in Pancreatic B Cell - A pharmaceutical for promoting neogenesis or regeneration of pancreatic β cells which produces and secretes insulin and for promoting insulin production in β cells, comprising ghrelin or a derivative thereof as an effective component.2009-06-04
20090143285TARGET PROTEIN AND TARGET GENE FOR DRUG DISCOVERY AND SCREENING METHOD - The present invention provides target proteins and target genes for bioactive substances such as drugs, and means that enable the development of novel bioactive substances using the same. More specifically, the present invention provides target proteins and target genes for bioactive substances; screening methods for substances capable of regulating bioactivities; bioactivity regulators; a bioactive substance derivative production method; a complex comprising a bioactive substance and a target protein, and a method of producing the complex; and kits comprising a bioactive substance or a salt thereof; determination methods for the onset or risk of onset of a specified disease or condition, determination methods for susceptibility to a bioactive substance, and determination kits used for the determination methods, and the like.2009-06-04
20090143286Methods and Compositions for Regenerating Articular Cartilage - Methods and compositions are described to regenerate cartilage in a partial thickness defect or area of reduced volume of articular cartilage comprising an infiltration suppressor agent and a columnar growth promoting agent.2009-06-04
20090143287TISSUE REGENERATION SUBSTRATE - The present invention provides a tissue regeneration substrate that has the ability to release a basic fibroblast growth factor (bFGF) and like cell growth factors in a sustained manner, into which cells can easily enter, and that is suitably used for regeneration of tissues. Specifically, the present invention provides a tissue regeneration substrate that comprises a cell growth factor adsorbed in a bioabsorbable porous substrate that contains collagen and gelatin, and a method for producing the same.2009-06-04
20090143288Peptide-complement conjugates - The current invention reports a polypeptide conjugate, wherein the conjugate comprises a first polypeptide selected from the group of polypeptides comprising SEQ ID NO: 01 and fragments thereof, and a second polypeptide selected from the group of antifusogenic peptides.2009-06-04
20090143289Orthopoxvirus vectors, genes and products thereof - An orthopoxvirus vector, such as vaccinia, is described in which the A46R protein from vaccinia, or a closely related protein from any orthopoxvirus is not expressed or is expressed but is non-functional. Also described is the use of a vaccinia virus A46R protein or a closely related protein from any orthopoxvirus, or a functional peptide, peptidometic, fragment or derivative thereof, or a DNA vector expressing any of the above in the modulation and/or inhibition of IL1R/TLR superfamily signalling.2009-06-04
20090143290TUMOR-INHIBITING PROTEIN AND THE USE THEREOF - The invention has disclosed a new tumor suppressor protein HCRP1, the polynucleotide sequences encoding this polypeptides, and methods for production of the polypeptide using the recombinant technology. The tumor suppression protein, HCRP1, is obtained through the positional candidate cloning strategy. It locates in 8p22 region of human chromosome. The full length cDNA for HCRP1 is 1917bp, which encodes a protein of 397 amino acids. When introduced into liver cancer cells, HCRP1 can inhibit the malignant transformation of liver cancer cells.2009-06-04
20090143291TUMOR ANTIGEN BASED ON PRODUCTS OF THE TUMOR SUPPRESSOR GENE WT1 - A tumor antigen that comprises, as an active ingredient, a product of the Wilms' tumor suppressor gene WT1 or a peptide composed of 7-30 contiguous amino acids containing an anchor amino acid for binding to major histocompatibility complex (MHC) class I in said amino acid sequence, and a vaccine comprising said antigen.2009-06-04
20090143292Liquid Formulation of G-CSF Conjugate - The present invention relates to a liquid pharmaceutical composition comprising a granulocyte colony stimulating factor polypeptide conjugated with a polymer. In various embodiments, the composition has a pH value in the range of 4.5 to 5.5. Exemplary compositions further comprise a surfactant and optionally one or more other pharmaceutically acceptable excipients. The invention provides, inter alia, formulations free from tartaric acid or salts thereof and/or from succinic acid and salts thereof as buffering agents. Exemplary formulations are essentially devoid of not amino acids as stabilizers. The composition has good storage stability and is especially useful for the prophylaxis and treatment of disorders and medical indications where granulocyte colony stimulating factor preparations are considered as useful remedies.2009-06-04
20090143293Peptide inhibitors of protein kinase C gamma for pain management - Peptide sequences derived from the V5 domain of isozymes of protein kinase C for use in pain management are described. Also described are compositions comprising the peptides for treating pain and/or inducing analgesia. Methods of pain treatment and methods of identifying compounds that mimic the activity of the peptides are also described.2009-06-04
20090143294METHODS OF TREATING VASODILATORY SHOCK - The invention encompasses methods of decreasing the lumenal diameter of a blood vessel by contacting the vessel with a myosin light chain phosphatase inhibitor.2009-06-04
20090143295PEPTIDE-BASED ANTIACNE REAGENTS - Peptide-based antiacne reagents, formed by coupling a skin-binding peptide with an antiacne agent, are described. The skin-binding peptide portion of the peptide-based antiacne reagent binds strongly to the skin, thus keeping the antiacne agent coupled to the skin for a long lasting effect. Skin care compositions comprising the peptide-based antiacne reagents are also provided as well as a method of treating or preventing skin acne.2009-06-04
20090143296METHODS AND COMPOSITIONS FOR THE REPAIR AND/OR REGENERATION OF DAMAGED MYOCARDIUM - Methods, compositions, and kits for repairing damaged myocardium and/or myocardial cells including the administration of cytokines are disclosed and claimed.2009-06-04
20090143297MODULATORS OF ANTIESTROGEN PHARMACOLOGY - A protein, designated ERCoA3 is provided. The ERCoA3 protein interacts with the estrogen receptor and the progesterone receptor and causes activation of these receptors is provided. Also provided are polynucleotides which encode ERCoA3 or block translation of the mRNA which encodes ERCoA3. Antibiodies that bind to one or more epitopes in the human ERCoA3 protein are provided. The present invention also relates to methods of inhibiting or reducing tamoxifen or estrogen induced proliferation of cancer cells, particularly breast cancer cells, endometrial cancer cells and uterine cancer cells. The method comprises reducing the activity or levels of ERCoA3 in such2009-06-04
20090143298Broad-Spectrum Delta-Endotoxins and Method and Kit for Detecting Same and for Detecting Polynucleotides Encoding Same - Disclosed are novel synthetically-modified 2009-06-04
20090143299NOVEL ANTIMICROBIAL PEPTIDES AND USE THEREOF - The invention relates to a molecule comprising at least the amino acid sequence X2009-06-04
20090143300Treatment of sepsis and septic shock using ghrelin and growth hormone - Methods are disclosed for treating sepsis and septic shock using a combination of ghrelin and growth hormone, and for using ghrelin to reduce organ and tissue injury and improve survival after combined radiation exposure and sepsis.2009-06-04
20090143301HIGH CALORIE NUTRITIONAL SUPPLEMENT - The invention provides a nutritional supplement comprising a protein source including milk protein isolate and/or canola plant protein, as well as related methods for its production and use in treating a nutritional deficiency in an individual.2009-06-04
20090143302PYRIMIDINE COMPOUNDS - This invention relates to a method for treating inflammatory diseases or immune diseases, developmental or degenerative diseases, or tissue injuries. The method includes administering to a subject in need thereof an effective amount of one or more compounds of formula (I). Each variable in this formula is defined in the specification.2009-06-04
20090143303Anti-invasive and anti-angiogenic compositions - A peptide compound having the sequence Lys-Pro-Ser-Ser-Pro-Pro-Glu-Glu [SEQ ID NO:2] or a substitution variant, addition variant or other chemical derivative thereof inhibits cell invasion, endothelial tube formation or angiogenesis in vitro. A number of substitution variants and addition variants of this peptide, preferably capped at the N- and C-termini, as well as peptidomimetic derivatives, are useful for treating diseases and conditions mediated by undesired and uncontrolled cell invasion and/or angiogenesis. Pharmaceutical compositions comprising the above peptides and derivatives are administered to subjects in need of such treatment in a dosage sufficient to inhibit invasion and/or angiogenesis. The disclosed compositions and methods are particularly useful for suppressing the growth and metastasis of tumors.2009-06-04
20090143308Yeast membrane protein expression system and its application in drug screening - The invention relates to an in vitro cell based expression system for overexpressing heterologous pump proteins associated with drug resistance into the membrane of the host cell for drug screening applications.2009-06-04
20090143309Isozyme-specific antagonists of protein kinase C - A method of changing or otherwise converting the biological activity of a PKC peptide agonist to a peptide antagonist is described. The method involves substituting one or more amino acid residues so as to effect a change in charge in the peptide and/or to otherwise make the sequence similar to a sequence derived from the PKC binding site on the RACK protein for the respective PKC enzyme. Methods of inhibiting the activity of a PKC enzyme, and various peptide antagonists of εPKC are also disclosed.2009-06-04
20090143310Method of stimulating the motility of the gastrointestinal system using ipamorelin - The present invention provides a method of stimulating the motility of the gastrointestinal system in a subject in need thereof, wherein the subject suffers from maladies (i.e., disorders, diseases, conditions, or drug- or surgery-induced dysfunction) of the gastrointestinal system, by administering to the subject a ghrelin mimetic, or pharmaceutically acceptable salt thereof. The invention also provides a method of treating a gastrointestinal malady by co-administering a ghrelin mimetic with a laxative, a H2009-06-04
20090143311Compositions comprising tripeptides inhibiting ace - The present invention describes the use of MAP and/or ITP or a salt thereof as a nutraceutical, preferably a medicament.2009-06-04
20090143312INHIBITORS OF SERINE PROTEASES, PARTICULARLY HEPATITIS C VIRUS NS3 PROTEASE - The present invention relates to compounds, methods and pharmaceutical compositions for inhibiting proteases, particularly serine proteases, and more particularly HCV NS3 proteases. The compounds, and the compositions and methods that utilize them, can be used, either alone or in combination to inhibit viruses, particularly HCV virus.2009-06-04
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