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22nd week of 2010 patent applcation highlights part 41
Patent application numberTitlePublished
20100136085COMPOSITIONS AND METHODS FOR ARTHRODETIC PROCEDURES - The present invention provides compositions and methods for facilitating fusion of bones in a joint. The present invention provides compositions and methods for promoting fusion of bones in arthrodetic procedures. In one embodiment, a method of performing an arthrodetic procedure comprises providing a composition comprising PDGF disposed in a biocompatible matrix and applying the composition to a site of desired bone fusion in a joint.2010-06-03
20100136086DYNAMIC BIOACTIVE NANOFIBER SCAFFOLDING - A resorbable bone graft scaffold material, including a plurality of overlapping and interlocking fibers defining a scaffold structure and plurality of pores distributed throughout the scaffold. The fibers are characterized by fiber diameters ranging from about 5 nanometers to about 100 micrometers, and the fibers are a bioactive, resorbable material.2010-06-03
20100136087Composition for Promoting Cartilage Formation or Repair Comprising a NELL Gene Product and Method of Treating Cartilage-Related Conditions Using Such Composition - Provided herein are a composition for promoting cartilage formation or regeneration comprising a NELL gene product and a method of treating cartilage-related conditions using such a composition.2010-06-03
20100136088MAGNETIZABLE TAMPON DEVICE - In a tampon device (2010-06-03
20100136089LOCATION OF FATTY ACID ESTERS ON TAMPONS AND TOXIN INHIBITING EFFICACY - The application of active ingredients, exemplified by GML, to absorbent fibers, such as rayon fibers, used in tampon manufacture at very low levels has been found to maintain efficacy in the inhibition of the production of toxic shock syndrome toxin one (TSST-1) produced by 2010-06-03
20100136090Helically-Shaped Drug Delivery System - The present invention relates to a helically-shaped medicated veterinary system suitable for delivery of a drug to the vaginal cavity of a female non-human mammal and to a method of manufacture. The drug delivery system is helically-shaped and comprises a three layered polymer fibre. The polymer fibre comprises a polymer core, a polymer intermediate layer comprising a drug, and a polymer skin. The medicated system provides a controlled delivery of drug to the vaginal cavity of the mammal. The present invention also relates to a process of making the springs.2010-06-03
20100136091METHODS, SYSTEMS, AND COMPOSITIONS FOR EXTRACELLULAR MATRIX PRODUCTION - Compositions, methods, and kits for repair and production of extracellular matrix are provided. In the broad aspect, the composition comprises a ligand of α5β1 integrin attached to a surface of a nanoparticle composed of a protein, with a proviso that the protein is not fibronectin.2010-06-03
20100136092TRANSDERMAL IMMUNE PREPARATION, METHOD FOR PRODUCTION OF THE SAME, AND TRANSDERMAL IMMUNIZATION METHOD USING THE SAME - This invention is concerned with transdermal immune preparations which can exhibit a high immunological activity without containing any adjuvant, methods for producing the preparation, and transdermal immunization methods using the preparation.2010-06-03
20100136093Immunotherapeutic Method For Increasing Groundnut Tolerance In A Subject - The present invention describes a new method for progressive desensitization of a subject to groundnut. More specifically, the invention relates to the immunotherapeutic method for increasing groundnut tolerance in an allergic subject using epicutaneous administration. The present invention is also relative to the use of a skin patch device for progressive desensitization of a subject to groundnut.2010-06-03
20100136094Systems for modulating inflammation - Certain embodiments disclosed relate to compositions, including therapeutic compositions, methods, devices, and systems that modulate at least one inflammatory response or reaction. According to various embodiments, the compositions, methods, devices, and systems relate to modulating one or more of Toll-like receptors, Src family kinases, NF-kB molecules, proteases, or proteasomes.2010-06-03
20100136095Systems for modulating inflammation - Certain embodiments disclosed relate to compositions, including therapeutic compositions, methods, devices, and systems that modulate at least one inflammatory response or reaction. According to various embodiments, the compositions, methods, devices, and systems relate to modulating one or more of Toll-like receptors, Src family kinases, NF-kB molecules, proteases, or proteasomes.2010-06-03
20100136096Systems for modulating inflammation - Certain embodiments disclosed relate to compositions, including therapeutic compositions, methods, devices, and systems that modulate at least one inflammatory response or reaction. According to various embodiments, the compositions, methods, devices, and systems relate to modulating one or more of Toll-like receptors, Src family kinases, NF-kB molecules, proteases, or proteasomes.2010-06-03
20100136097Systems for modulating inflammation - Certain embodiments disclosed relate to compositions, including therapeutic compositions, methods, devices, and systems that modulate at least one inflammatory response or reaction. According to various embodiments, the compositions, methods, devices, and systems relate to modulating one or more of Toll-like receptors, Src family kinases, NF-kB molecules, proteases, or proteasomes.2010-06-03
20100136098AVIAN INFLUENZA VACCINE - The present invention provides an avian influenza vaccine containing a peptide-bound liposome wherein; 2010-06-03
20100136099LIPOSOME FOR INDUCTION OF CELL-MEDIATED IMMUNITY - Disclosed is a liposome which includes an antigenic substance therein and has, on its surface, a peptide containing several contiguous arginine residues. The liposome enables an antigen-presenting cell to achieve the selective antigen presentation through an MHC Class-I molecule, and can induce a cell-mediated immunity specifically. The liposome can also induce the antigen presentation by a matured dendritic cell.2010-06-03
20100136100Removal promoters and inhibitor for apoptosis cells in vivo - The present invention is to provide a removal promoter for apoptotic cells which is capable of immediately removing apoptotic cells in vivo by macrophages, or a removal inhibitor which inhibits the removal of apoptotic cells in vivo by macrophages. A removal promoter for apoptotic cells in vivo containing the milk fat globule-EGF factor 8-L (MFG-E8-L), MFG-E8-L mutant having removal promotion action for apoptotic cells in vivo by macrophages, or preferably a recombinant human or mouse MFG-E8-L, or a recombinant human or mouse MFG-E8-L mutant as an active ingredient is prepared. Such removal promoters specifically bind to apoptotic cells and promote the phagocytosis of apoptotic cells by macrophages by recognizing aminophospholipids such as phosphatidylserine exposed on apoptotic cell surface. On the other hand, a point mutation (D89E) MFG-E8-L mutant is used as a removal inhibitor.2010-06-03
20100136101COMPOSITIONS AND METHODS FOR SIRNA INHIBITION OF HIF-1 ALPHA - RNA interference using small interfering RNAs which target HIF-1 alpha mRNA inhibit expression of the HIF-1 alpha gene. As HIF-1 alpha is a transcriptional regulator of VEGF, expression of VEGF is also inhibited. Control of VEGF production through siRNA-mediated down-regulation of HIF-1 alpha can be used to inhibit angiogenesis, in particularly in diseases such as diabetic retinopathy, age related macular degeneration and many types of cancer.2010-06-03
20100136102TERPENE-CONTAINING COMPOSITIONS AND METHODS OF MAKING AND USING THEM - The present invention relates to compositions comprising terpenes and hollow glucan particles or cell wall particles and methods for preparing such compositions. The compositions increase terpene stability and activity and provide a suitable carrier for the terpenes. The invention also relates to methods of using such compositions,in the medical, veterinary and agricultural fields.2010-06-03
20100136103COSMETIC ANTI-AGEING SKIN CARE COMPOSITIONS - The invention is directed to an anti ageing skin care composition, more in particular a cosmetic anti aging skin care composition. The anti ageing skin care composition of the invention comprise, in a physiologically acceptable medium, (i) at least one peptide from Laminin-1 that is able to promote synthesis of Laminin-5; (ii) at least one peptide capable of at least partially inhibiting neuronal exocytosis; and (iii) at least one tripeptide producing a rapid and strong stimulation of collagen synthesis. The compositions of the present invention are effective in reducing existing wrinkles and/or preventing the formation of new wrinkles.2010-06-03
20100136104NUTRITIONAL SUPPLEMENT FOR USE UNDER PHYSIOLOGICALLY STRESSFUL CONDITIONS - In one embodiment of the present invention, a pharmaceutically-acceptable single-dosage formulation consists essentially of about 300 mg of vitamin C; about 1200 IUs of vitamin D3; about 125 IUs of vitamin E; about 25 mg of vitamin B1; about 3.4 mg of vitamin B2; about 35 mg of niacin; about 35 mg of vitamin B6; about 1.25 mg of folate; about 70 mcg of vitamin B12; about 5 mg of pantothenic acid; about 300 mcg of biotin; about 50 mg of calcium; about 35 mg of magnesium; about 35 mg of zinc; about 1 mg of copper; about 125 mcg of selenium; about 150 mcg of chromium; about 25 mg of alpha lipoic acid; about 35 mg of co-enzyme Q-10; about 2 mg of lutein; about 500 mcg of lycopene; about 5 mg of pepper extract; and at least one or more excipients.2010-06-03
20100136105PHARMACEUTICAL COMPOSITIONS AND DOSAGE FORMS FOR ADMINISTRATION OF HYDROPHOBIC DRUGS - The present invention relates to pharmaceutical compositions and methods for improved solubilization of triglycerides and improved delivery of therapeutic agents. Compositions of the present invention include a carrier, where the carrier is formed from a combination of a triglyceride and at least two surfactants, at least one of which is hydrophilic. Upon dilution with an aqueous medium, the carrier forms a clear, aqueous dispersion of the triglyceride and surfactants.2010-06-03
20100136106Modified Release Famciclovir Compositions - The invention relates to a multiparticulate modified release composition that, upon administration to a patient, delivers famciclovir in a bimodal, multimodal or continuous manner. The multiparticulate modified release composition comprises a first component and at least one subsequent component, the first component comprising a first population of active ingredient containing particles and the at least one subsequent component comprising a second population of active ingredient containing particles. The invention also relates to a solid oral dosage form containing such a multiparticulate modified release composition, and to a method for the treatment or suppression of viral infections.2010-06-03
20100136107Liquid Therapeutic Composition - A liquid composition includes a therapeutic component dispersed in a liquid carrier system. The liquid carrier system is made up of water and a solvent. The solvent includes at least 90 wt % propylene glycol and less than 2 wt % ethanol, if ethanol is present in the solvent. The therapeutic component has acetaminophen and phenylephrine. The weight ratio of solvent to phenylephrine is between 100:1 to 2000:1. The weight ratio of solvent to acetaminophen is between 5:1 and 25:1.2010-06-03
20100136108FORMULATION FOR RETINOID-CONTAINING SOFT GELATIN CAPSULES - A new pharmaceutical formulation for retinoid-containing soft gelatin capsules is disclosed. The new formulation comprises a soft gelatin capsule filled with a fill mass comprising a retinoid as an active ingredient, a natural vegetable oil, a partially hydrogenated natural vegetable oil and medium chain triglycerides. Optionally, the new formulation also comprises a natural wax. In a particularly preferred embodiment, the soft gelatin capsule comprises pig gelatin in the capsule shell in combination with the above fill mass.2010-06-03
20100136109SUSTAINED RELEASE - We describe a medicament for the treatment of thyroid disorders that typically result from a hypoactive thyroid gland that releases thyroxine and triiodothyronine in a sustained pattern when administered to a subject.2010-06-03
20100136110GRANULAR PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION - A granular pharmaceutical composition for oral administration, wherein a drug-containing particle is coated with a coating comprising a methyl methacrylate-butyl methacrylate-dimethylaminoethyl methacrylate copolymer and a water-soluble polymer is disclosed.2010-06-03
20100136111PHARMACEUTICAL COMPOSITIONS OF DICLOFENAC AND MISOPROSTOL - The present invention relates to pharmaceutical compositions of diclofenac or pharmaceutically acceptable salts thereof and misoprostol or pharmaceutically acceptable salts thereof. The invention also relates to processes for the preparations of such compositions.2010-06-03
20100136112Oxidizing composition including a gel layer - A composition that generates and releases a biocidal solution comprising at least chlorine dioxide is presented. The composition comprises reactants capable of in-situ generation of chlorine dioxide, and a gelling agent that slows the rate of dissolution of the reactants, thereby increasing yield and providing a controlled release of biocidal solution. The compositions of the invention show improved environmental stability which can reduce the cost of packaging. The controlled release allows the use in multi-tablet chemical dispensers which may otherwise induce potentially explosive conditions or allow rapid release of the biocidal solution thereby inducing a spike in chemical concentration rather than a sustained release.2010-06-03
20100136113PHYTASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM - This invention relates to phytases, polynucleotides encoding them, uses of the polynucleotides and polypeptides of the invention, as well as the production and isolation of such polynucleotides and polypeptides. In particular, the invention provides polypeptides having phytase activity under high temperature conditions, and phytases that retain activity after exposure to high temperatures. The phytases of the invention can be thermotolerant and/or thermostable at low temperatures, in addition to higher temperatures. The phytases of the invention can be used in foodstuffs to improve the feeding value of phytate rich ingredients. The phytases of the invention can be formulated as foods or feeds or supplements for either to, e.g., aid in the digestion of phytate. The foods or feeds of the invention can be in the form of pellets, liquids, powders and the like. In one aspect, phytases of the invention are stabile against thermal denaturation during pelleting; and this decreases the cost of the phytase product while maintaining in vivo efficacy and detection of activity in feed.2010-06-03
20100136114DE NOVO FORMATION AND REGENERATION OF VASCULARIZED TISSUE FROM TISSUE PROGENITOR CELLS AND VASCULAR PROGENTITOR CELLS - It has been discovered that vascularized tissue or organs can be engineered by combined actions of tissue progenitor cells and vascular progenitor cells. Provided herein are compositions and methods directed to engineered vascularized tissue or organs formed by introducing tissue progenitor cells and vascular progenitor into or onto a biocompatible scaffold of matrix material. Also provided are methods of treating tissue defects via grafting of such compositions into subjects in need thereof.2010-06-03
20100136115Pharmaceutical Titanium Dioxide Composite Allowing Disappearance of Drug Efficacy By Light Irradiation - Disclosed is a titanium dioxide composite material which can be dispersed in an aqueous solvent stably and can be administered to a living body in a simple manner and in which the pharmacological effect of a therapeutic compound carried on the composite material can be eliminated by irradiation with light. Also disclosed is a dispersion product of the composite material. The composite material comprises titanium dioxide which has a photocatalytic activity and a therapeutic compound attached to the titanium dioxide through a hydrophilic polymer. The composite material is stable in an aqueous solvent and can be administered to a living body in a simple manner. After the composite material is administered to a living body, a site on the living body where the pharmacological effect of the therapeutic compound is not needed to be developed can be irradiated with light to induce the light excitation of titanium dioxide at the site, thereby decomposing the therapeutic compound to reduce any adverse side effect of the therapeutic compound.2010-06-03
20100136116NOVEL HYDRATED FORM OF ERLOTINIB FREE BASE AND A PROCESS FOR PREPARATION OF ERLOTINIB HYDROCHLORIDE POLYMORPH FORM A SUBSTANTIALLY FREE OF POLYMORPH FORM B - The present invention provides a novel and stable hydrated form of erlotinib free base, and a process for its preparation thereof. The present invention also provides a process for preparation of erlotinib hydrochloride crystalline polymorph A substantially free of polymorph B. The present invention further relates to erlotinib hydrochloride crystalline particles having mean particle size (D2010-06-03
20100136117HYDROXYAPATITE TISSUE FILLER AND ITS PREPARATION AND USE - The invention pertains to a biocompatible composition, suitable for use in soft or hard tissue augmentation, wherein the composition is an aqueous suspension containing a carrier fraction of ceramic particles of less than 15 &mgr;m and an augmentation fraction of ceramic particles of at least 20 &mgr;m. The ceramics typically comprise calcium phosphate. The composition is a may be used in soft tissue repair as well as hard bone replacement. It advantageously avoids the need for foreign body materials which are conventionally applied to stabilize augmentation suspensions.2010-06-03
20100136118CALCIUM ABSORPTION ENHANCER - The present invention provides a calcium absorption enhancer that places no burden on the body of a human or a domestic animal to which a calcium compound is administered and can increase the efficiency with which a calcium content is absorbed into the body by supplying calcium ions in the stomach or the like of the human or the domestic animal in a sustained-release manner after administration of the calcium compound. The calcium absorption enhancer of the present invention contains, as an active ingredient, water-soluble calcium particles that can release calcium ions in an aqueous solution in a sustained-release manner.2010-06-03
20100136119CONTROLLED-RELEASE PREPARATION CONTAINING CILOSTAZOL AND PROCESS FOR THE PREPARATION THEREOF - A controlled release preparation which comprises particles containing cilostazol or its pharmaceutically acceptable salt dispersed in a solubilizing agent and an erodible material encasing said particles which is capable of forming a hydrogel, can maintain a constant level of cilostazol in the blood through its slow release during its prolonged residence time in the stomach and intestines, thereby minimizing adverse effects caused by rapid release of the drug or solubilizing agent.2010-06-03
20100136120COMPOSITIONS AND METHODS FOR FORMING AND STRENGTHENING BONE - Compositions are provided which stimulate bone growth. Also provided are methods for utilizing the compositions for filling in bone defects, promoting rapid fusion of bone fractures, grafts, and bone-prostheses, and promoting strengthening of osteoporotic bones.2010-06-03
20100136121MEDICAMENTS - There is described a bimodal pharmaceutical composition comprising effective amounts of a first active ingredient which substantially comprises a coarse fraction and a second active ingredient which substantially comprise a fine fraction characterized in that the coarse fraction possesses a greater mass median aerodynamic diameter than the fine fraction. There is also described a method of delivering a therapeutically effective amount of a substantially fine active ingredient to the lung of a patient by co-administration with a substantially coarse active ingredient.2010-06-03
20100136122Oral Preparation Comprising Pioglitazone - The present invention provides an oral preparation sufficiently masking the bitter taste of pioglitazone and a salt thereof. The present invention provides an oral preparation containing pioglitazone or a salt thereof and alkali metal chloride.2010-06-03
20100136123Microcapsule Sheet - In order to heighten the density of microcapsules and facilitate handling by the unit composed of microcapsules in a given amount smaller than in the whole sheet, a microcapsule sheet which comprises a substrate constituted of an edible film and microcapsules each obtained by surrounding a core layer with a first shell film and a second shell film, the microcapsules being arranged according to a given pattern so as to be arranged only in those regions of the substrate which are separated from each other.2010-06-03
20100136124NANOPARTICLE-COATED CAPSULE FORMULATION FOR DERMAL DRUG DELIVERY - A method and formulation for the delivery of an active substance to the skin (epidermis, including the stratum corneum and viable epidermis, and dermis) of a subject. The formulation comprises oil-based or aqueous droplets comprising the active substance within a coating of nanoparticles, particularly silica nanoparticles. The active substance may be suitable for the treatment of a disease or condition which is localised, or at least partially localised, to the skin (eg skin cancer, psoriasis, eczema, infections including bacterial and fungal infections, acne, dermatitis, inflammation, and rheumatoid arthritis).2010-06-03
20100136125METHOD OF TREATING INFLAMMATORY BOWEL DISEASE - Methods are disclosed for treating patients suffering from inflammatory bowel disease, including ulcerative colitis or Crohn's disease, by administering an oral or enema dosage form containing at least one aminosalicylate active ingredient. Granular dosage forms and kits are also disclosed.2010-06-03
20100136126COMPOSITION AND MICROSPHERE FOR CONTROLLED-RELEASE OF EXENDIN, AND METHOD OF PREPARING THE SAME - A controlled-release composition and controlled-release microspheres containing an exendin as an active ingredient, and a method of preparing the same are provided. More specifically, a controlled-release composition containing an exendin as an active ingredient, a biodegradable polymer with a specific viscosity, and coating materials, having high bioavailability and showing sustained release of the active ingredient in an effective concentration for a certain period without an excessive initial burst of the active ingredient; controlled-release microspheres containing a core including an exendin as an active ingredient and a biodegradable polymer, and a coating layer coating the core; and a method of preparing controlled-release microspheres including the steps of mixing an exendin, a biodegradable polymer, and a solvent, removing the solvent from the mixture to prepare hardened microspheres, and coating the hardened microspheres to form a coating layer on the surface of each microsphere, are provided.2010-06-03
20100136127SOLID PREPARATION COMPRISING ALOGLIPTIN AND METFORMIN HYDROCHLORIDE - The present invention provides a solid preparation containing compound (I) [compound (I) is as defined in the specification] or a salt thereof, and metformin hydrochloride, which is useful as a therapeutic drug for diabetes and the like, and superior in the preservation stability. A solid preparation having a first part and a second part: a first part: a part containing compound (I) or a salt thereof and substantially free of metformin hydrochloride a second part: a part containing metformin hydrochloride and substantially free of compound (I) and a salt thereof.2010-06-03
20100136128Odor control fragrance additive - An odor control fragrant additive comprises compacted pellets or granules infiltrated with fragrant oil. Cellulosic material, activated carbon and binder are mixed together and compacted to produce compacted pellets or granules. The cellulosic material preferably is peat moss, which swells up during absorption of fragrant oil and acts as fragrant oil storage. Fragrant oil is delivered to activated carbon that has large surface area, which evaporates the fragrance oil to release steady fragrance output. Thus, the activated carbon, which evaporates fragrance provides steady release of fragrance in the surrounding environment of fragrant compacted pellets or granules for a period of several months without overpowering the environment with excess fragrance. The fragrant compacted pellets or granules may be used to suppress malodor from trashcans or litter boxes and may provide stand-alone additions to drawers and cabinets, emitting pleasant fragrance.2010-06-03
20100136129NANOPARTICLES COMPRISING A CYCLODEXTRIN AND A BIOLOGICALLY ACTIVE MOLECULE AND USES THEREOF - The invention relates to nanoparticles comprising a biodegradable polymer, a cyclodextrin or a derivative thereof, and a biologically active molecule. Said nanoparticles can associate large amounts of biologically active molecules, especially of a hydrophobic nature, and release the biologically active molecule providing sustained and constant plasma levels thereof when they are administered orally or through any other mucosa of the organism.2010-06-03
20100136130Preparation for the Controlled Release of Bioactive Natural Substances - The present invention relates to a preparation comprising at least one encapsulation material and at least one bioactive natural substance, which bioactive natural substance can be released from the preparation in a controlled manner, wherein the encapsulation material comprises at least one glyceride with a melting point of at least 35° C. and additionally at least one polymer with polyester units, which has a melting temperature of at least 30° C. and a viscosity in the range from 50 mPa*s to 250 Pa*s, measured by means of rotational viscometry at 110° C. The present invention further describes processes for producing the preparation of the invention, as well as preferred uses.2010-06-03
20100136131COMPOSITE MATERIAL - The present invention provides a composite material comprising fibrinogen or fibrin, or a mixture thereof, and a bioactive glass. The invention also relates to wound dressings and pharmaceutical compositions containing the composite material. Further aspects of the invention relate to the use of the composite material of the for treating a wound, treating or preventing bacterial infections in a wound, preventing or alleviating bleeding in a wound, sterilising a wound, controlling haemorrhaging, increasing the rate of coagulation of blood and/or activating a coagulation system in a wound.2010-06-03
20100136132LIGNOSULFONATE COMPOSITIONS FOR CONTROL OF PLANT PATHOGENS - The present invention relates to a composition comprising a soluble combination comprising lignosulfonate, a metal salt, and a phosphorous compound selected from the group consisting of phosphorous acid and spontaneously soluble salts thereof, and mixtures thereof. The present invention also relates to the use of such compositions as pesticides.2010-06-03
20100136133NUTRITIVE COMPOSITIONS AND METHODS OF USING SAME - The invention provides intradialytic parenteral nutrition (IDPN) solutions with low carbohydrate for the treatment of malnutrition in dialysis patients. The IDPN solutions of the invention are particularly advantageous for the treatment of malnutrition in patients who are diabetic or suffer from other glucose management related pathologies or patients who require strict fluid management.2010-06-03
20100136134Immune stimulatory infant nutrition - A nutritional or pharmaceutical composition containing a fat component, a protein component and a carbohydrate component and comprising whey and casein. The composition has a weight ratio of casein to whey is 1:1 to 1:2.4 and that the composition contains: a) at least 3 grams arginine per 100 grams protein; b) at least 10 wt. % linoleic acid based on total fatty acids; c) at least 1 wt. % alpha linolenic acid based on total fatty acids; d) at least one long chain-polyunsaturated fatty acid in an amount exceeding 0.1 wt. % based on total fatty acids. The long chain polyunsaturated fatty acid being docosahexaenoic acid, arachidonic acid and eicosapentaenoic acid; e) 5 to 25 wt. % of at least one polyunsaturated fatty acid based on total fatty acids; and f) 2 to 12 grams indigestible oligosaccharides having a degree of polymerisation of 2 to 100 per 100 gram dry weight of the composition. The composition reduces—among others—the risks attached to feeding whey dominant infant formula.2010-06-03
20100136135Method of Selecting Phosphate Binder and its Uses Thereof - A method of selecting or determining a candidate compound suitable for use as a phosphate binder is disclosed. The candidate compound includes ferric compounds, ferric compound complexes, and their derivatives, salts, analogs, and metabolites. The effectiveness of the candidate compound as a phosphate binder is evaluated by a method, comprising measuring and correlating reduction of phosphate concentration in solution and reduction of phosphate absorption in cells.2010-06-03
20100136136JAK-2 Modulators and Methods of Use - This invention relates to the field of protein tyrosine kinases and inhibitors thereof. In particular, the invention relates to inhibitors of JAK-2, pharmaceutical compositions of the compounds for inhibiting JAK-2, methods of inhibiting JAK-2 in a cell, comprising contacting a cell in which inhibition of JAK-2 is desired with a compound or pharmaceutical composition comprising a compound according to the invention. The also comprises methods of treating a disease or condition that involves JAK-2 comprising administering to a patient a pharmaceutical composition comprising a compound according to the invention.2010-06-03
20100136137THERAPEUTIC COMBINATION OF A PANHER/VEGFR2 KINASE INHIBITOR AND A PLATINUM COMPOUND - This invention relates to a synergistic therapeutic combination of anti-cancer compounds which comprises a) a panHER/VEGFR2 kinase inhibitor, and b) a platinum compound, and optionally at least one pharmaceutically acceptable carrier for simultaneous, separate or sequential use. The invention also relates to treating certain cancers utilizing the combination of the invention.2010-06-03
20100136138TREATMENT OF LUNG CANCER - Disclosed are methods of treating lung cancer by administering to a human in need thereof effective amounts of FTS, or various analogs thereof, or a pharmaceutically acceptable salt thereof, optionally, in combination with a chemotherapeutic agent. Chemotherapeutic agents, and combinations thereof, for use with FTS, its analogs, or its salts are also disclosed.2010-06-03
20100136139CANCER MARKER AND THERAPEUTIC AGENT FOR CANCER - A novel cancer marker is provided. A method for detecting cancer using a level of BMCC1 gene expression as an indication is provided, in which the cancer is selected from the group consisting of prostate cancer, lung cancer, gastric cancer, bladder cancer, and uterine cancer.2010-06-03
20100136140A USE OF HYPERTONIC SOLUTION COMPOSITION IN MANUFACTURING MEDICAMENTS FOR PROMOTING WOUND HEALING - A use of a hypertonic solution composition in manufacturing medicaments used during the perioperative period for promoting wound healing, said composition consists of 1.5%-6.9% (w/v) of one or more substances selected from sodium chloride, sodium bicarbonate, potassium chloride, magnesium sulfate, calcium chloride and calcium gluconate, 3%-18% (w/v) of one or more of the substances selected from hydroxyethyl starch, dextran, carboxymethyl starch, polyvinyl pyrrolidone and gelatin derivatives, and the remainder of conventional injection, provided that the amount of sodium chloride in the composition is not less than 1.5% (w/v), and the concentration of sodium ion is not more than the one equivalent to the concentration of sodium ion in 6.9% (w/v) sodium chloride solution. The hypertonic solution composition can be administered as transfusion before operation, during operation, after operation with the dose of 100-1500 ml/person/day, which can promoter wound healing. The hypertonic solution composition is advantageous in terms of the safety and convenience of application. Said composition can applied to various operative wounds or trauma wound (surface) as well as anastomotic stoma.2010-06-03
20100136141Hemostatic agent - A generally non-acidic hemostatic agent, having a relatively neutral pH comprising a magnesium compound, such as a magnesium chloride, a magnesium sulfate and/or a magnesium acetate based compound. The resultant agent is generally less caustic than previous agents, when using a similar amount of active material.2010-06-03
20100136142SUBSTITUTED-4-ARYL-1,4-DIHYDRO-1,6-NAPHTHYRIDINAMIDES AND USE THEREOF - The present application relates to novel substituted 4-aryl-1,4-dihydro-1,6-naphthyridine-3-carboxamides, a process for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially cardiovascular disorders.2010-06-03
20100136143NEW COMPOSITIONS AND METHODS FOR CELL KILLING - The present invention discloses an insoluble proton sink or source (PSS), useful for killing living target cells (LTCs), or otherwise disrupting vital intracellular processes and/or intercellular interactions of the LTC upon contact. The PSS comprises (i) proton source or sink providing a buffering capacity; and (ii) means providing proton conductivity and/or electrical potential. The PSS is effectively disrupting the pH homeostasis and/or electrical balance within the confined volume of the LTC and/or disrupting vital intercellular interactions of the LTCs while efficiently preserving the pH of the LTCs' environment. The invention also provides articles of manufacture comprises the PSS and presents an effective method for killing the LTCs.2010-06-03
20100136144COMPOSITION CONTAINING A QUINOA EXTRACT FOR DERMATOLOGICAL USE - The present invention relates to a composition containing a quinoa grain extract, said extract being a peptidic and osidic extract or a lipidic extract of quinoa grain, said lipid quinoa extract being itself chosen from a group comprising an oil concentrated into its non saponificable fraction, a non saponificable, or a refined oil. The invention also relates to methods for preparing these different extracts and to dermatological or neutraceutic applications of these extracts.2010-06-03
20100136145FORMULATIONS CONTAINING CYNARA SCOLYMUS AND PHASEOLUS VULGARIS EXTRACTS WHICH ARE USEFUL IN THE TREATMENT OF OBESITY2010-06-03
20100136146COMPOSITION FOR HEART DISEASE, ITS ACTIVE INGREDIENTS, METHOD TO PREPARE SAME AND USES THEREOF - This invention provides a composition for heart disease comprising extracts from raw herbs of 80.0-97.0% Radix 2010-06-03
20100136147DIET SUPPLEMENT FOR CAUSING WEIGHT LOSS - A dietary supplement and method for supporting weight loss and reducing the waist circumference of an individual, the dietary supplement comprising an extract of 2010-06-03
20100136148GREEN DISINFECTION/SANITIZATION COMPOSITIONS AND PROCESSES OF MAKING THEREOF - Cleaning and disinfecting compositions containing one or more “green” surfactants are disclosed. The compositions may be present as micro-emulsions that generally include green disinfecting agents, green surfactants, and water. The composition may also contain other green ingredients such as linkers, pH adjusting agents, natural fragrances, natural insecticides, and other natural organic actives such as natural oils. The composition may be used as a green cleaning and disinfecting composition with performance comparable or superior to conventional cleaning and disinfecting products with less desirable ecological profiles.2010-06-03
20100136149METHOD FOR PRODUCING VEGETABLE CELL SAP CONCENTRATE AND MEANS FOR THE PRODUCTION THEREOF - The invention relates to extracting biologically active substances from raw vegetable matter, consists in using a liquefied carbon dioxide and can be used in the pharmaceutical, perfume-and-cosmetic and food industries. The aim of the invention is to produce a cell sap concentrate by using liquefied carbon dioxide for the irradiation thereof. The inventive method consists in extracting a milled matter by means of liquefied carbonic acid at room temperature and in separating an oil fraction, wherein the extraction is carried out at a high rate of the liquefied carbonic acid with a proportion of not less than 11 of carbonic acid per 1 g of extracted vegetable cell sap and a vegetable cell sap concentrate is produced by separating the oil fraction from a water fraction.2010-06-03
20100136150PHARMACEUTICAL COMPOSITION FOR TREATING DIABETES AND ITS PROCESS FOR PREPARATION - The present invention relates to methods for preparing a pharmaceutical composition for treating diabetes mellitus and the pharmaceutical composition prepared by the methods. The pharmaceutical composition of the present invention comprises extracts of the following crude drugs: 5-40 weight parts of 2010-06-03
20100136151OPTICAL TAPE EMBOSSING DRUM AND OPTICAL TAPE EMBOSSING DRUM SHIM - Disclosed herein are aspects of optical tape technology, tape manufacturing, and tape usage. Methods and systems of tape technology disclose optical tape media including: configurations, formulations, markings, and structure; optical tape manufacturing methods, systems, and apparatus methods and systems including: curing processes, coating methods, embossing, drums, testing, tracking alignment stamper strip; optical tape methods and systems including: pick up head adapted for the disclosed optical tape; and optical tape uses including optical storage media devices for multimedia applications2010-06-03
20100136152GUIDE ELEMENT FOR A TUBULAR FILM - A guide element for a tubular film which is produced by blown film extrusion. The guide element includes a support structure having guides secured to the support structure and acting upon the circumference of the tubular film. The support structure includes a plurality of support limbs that are articulated to each other and that are received so as to be adjustable relative to each other by adjusting drives. At least one guide for the tubular film is secured to each support limb.2010-06-03
20100136153PREPARATION OF INDIVIDUALLY COATED COMPOSITE FRUIT PRODUCTS - A method and apparatus for producing individually coated, baked, composite fruit core snack products is disclosed. Wet and dry ingredients are mixed and extruded to make a fruit paste rope. The fruit paste rope is divided into individual sections and formed into cores, each of which is substantially shaped into a sphere. The cores are then coated and baked to produce the coated composite fruit snack product.2010-06-03
20100136154STAMPER AND METHOD FOR MAKING SOFT MOLD - An exemplary method for making a soft mold is provided. A transparent substrate is provided. A to-be-solidified film is formed on the transparent substrate. A stamper and a guiding plate are further provided. The guiding plate is positioned between the stamper and the to-be-solidified film. The stamper inserts one of the through holes of the guiding plate. The first alignment mark is aligned with one of the second alignment marks. The stamper is pressed into the to-be-solidified film. The pressed portion of the to-be-solidified film is solidified to obtain a second molding surface on the to-be-solidified film. The previous steps are repeated for the stamper and the rest of the through holes of the guiding plate to obtain a soft mold having a plurality of the second molding surfaces.2010-06-03
20100136155MANUFACTURING APPARATUS OF FIBER-REINFORCED RESIN STRAND - There is provided a manufacturing apparatus of a fiber-reinforced resin strand equipped with a roller offset angle adjusting device which can easily adjust roller offset angles of a pair of twisting rollers for twisting a fiber-reinforced resin strand, the device being simple in structure.2010-06-03
20100136156PLANT FOR PRODUCTION OF CONCRETE - The invention relates to a plant for the production of concrete, comprising a mould for a molded concrete mass (2010-06-03
20100136157Mold for Extrusion Molding a Medical Application Tube and Extrusion Molding Method - A mold for extrusion molding a medical application tube and the extrusion molding method thereof in which the medical application tube having a complex profile can be molded by using a soft thermoplastic resin.2010-06-03
20100136158Liquid or Hydraulic Blow Molding - An apparatus and method for simultaneously forming and filling a plastic container is provided. A mold cavity defines an internal surface and is adapted to accept a preform. A pressure source includes an inlet and a piston-like device. The piston-like device is moveable in a first direction wherein liquid is drawn into the pressure source through the inlet and in a second direction wherein the liquid is urged toward the preform. A blow nozzle may be adapted to receive the liquid from the pressure source and transfer the liquid at high pressure into the preform thereby urging the preform to expand toward the internal surface of the mold cavity and create a resultant container. The liquid remains within the container as an end product.2010-06-03
20100136159ACCELERATOR FEED ARRANGEMENT CONFIGURED TO ACCELERATE BLOW-MOLDED PET BEVERAGE BOTTLES FROM A LINEAR CONVEYOR TO A ROTARY PET BOTTLE STERILIZING MACHINE AND MINIMIZE MISALIGNMENT AND JAMMING OF BLOW-MOLDED PET BEVERAGE BOTTLES DURING TRANSPORT FROM A LINEAR CONVEYOR TO A ROTARY PET BOTTLE STERILIZING MACHINE - An accelerator feed arrangement configured to accelerate blow-molded pet beverage bottles from a linear conveyor to a rotary pet bottle sterilizing machine and minimize misalignment and jamming of blow-molded pet beverage bottles during transport from a linear conveyor to a rotary pet bottle sterilizing machine. The abstract of the disclosure is submitted herewith as required by 37 C.F.R. §1.72(b). As stated in 37 C.F.R. §1.72(b): A brief abstract of the technical disclosure in the specification must commence on a separate sheet, preferably following the claims, under the heading “Abstract of the Disclosure.” The purpose of the abstract is to enable the Patent and Trademark Office and the public generally to determine quickly from a cursory inspection the nature and gist of the technical disclosure. The abstract shall not be used for interpreting the scope of the claims. Therefore, any statements made relating to the abstract are not intended to limit the claims in any manner and should not be interpreted as limiting the claims in any manner.2010-06-03
20100136160OVEN FOR THE THERMAL CONDITIONING OF PREFORMS, COMPRISING A VENTILATION PLENUM2010-06-03
20100136161SWEETENER-CONTAINING ANIMAL FOOD AND ANIMAL-FOOD ADDITIVE - The invention relates to animal food containing one or more conventional animal food ingredients selected from among cereal, cereal products, proteins, amino acids, vitamins, enzymes, mineral additives, and flavors, or an animal food additive for producing such animal food. Said animal food or animal food additive contains a sweetener combination which stimulates the appetite and/or improves performance and comprises at least naringin dihydrochalcone and a saccharin.2010-06-03
20100136162DENTAL DIET FOR REDUCING TARTAR - A dried pet food which is able to mechanically clean the teeth of pets when chewed. The pet food is based on a matrix of a protein source and a carbohydrate source. The density of the product is less than 20.5 lbs/ft2010-06-03
20100136163METHOD OF WEIGHT CONTROL EMPLOYING CHEWING GUM - The present invention is directed to methods for managing body weight by substituting a chewing gum composition on a regular basis for a snack product having a greater caloric content than the chewing gum composition or by employing a chewing gum composition in conjunction with behavior modification. Additionally, the present invention includes a method of controlling behavior modification relating to weight loss including identifying the behavior to be modified, setting behavioral goals relating to weight management, modifying determinants of the behavior to be changed using, in part, a chewing gum composition, and reinforcing the desired behavior using, in part, a chewing gum composition.2010-06-03
20100136164PACKAGE ASSEMBLY FOR MULTI-MODALITY TASTE CHEWING GUM COMPOSITIONS - A package assembly for a multi-layer center-filled chewing gum is disclosed. The package assembly supports individual gum pieces that have a center surrounded by a gum region. The gum region may include a gum base. Optionally, the individual gum pieces may be further coated with an external coating layer. Components of the individual gum pieces create a duality, such as two tastants, that are identified by indicia on the package.2010-06-03
20100136165CONFECTIONERY COMPOSITION, ARTICLE, METHOD, AND APPARATUS - A dough-like confectionery material contains a solid particulate, a liquid, and a diffusion controller. The dough-like confectionery material is an effective replacement for panned coatings, and it can be applied to an edible substrate, such as candy or chewing gum to form a layered confection. Methods and apparatus for forming layered confections are also described.2010-06-03
20100136166DAIRY PRODUCT AND PROCESS - The invention is a method of preparing a gel. The method comprises forming an oil-in-water emulsion by mixing oil or fat with an aqueous medium. The mixture comprises 2% to 12% (w/w) of a heat-settable protein and 5% to 40% (w/w) oil or fat or a mixture of oil and fat. The mixture is homogenised at a pressure in the range 100 to 2000 bar. The homogenised emulsion is heated to 50° C. to 200° C. for a period sufficient to denature the proteins without allowing a gel to form. A gel is formed by adding a salt or by acidifying. The proteins used include whey protein and soy protein.2010-06-03
20100136167METHOD FOR PRODUCTION OF PROCESSED LIVESTOCK MEAT FOOD OR PROCESSED SEA FOOD, AND ENZYME PREPARATION FOR IMPROVEMENT OF PROCESSED LIVESTOCK MEAT FOOD OR PROCESSED SEA FOOD - A processed meat food or a processed fishery food having improved physical properties and taste can be obtained by contacting meat or fish with a transglutaminase and an enzyme having a saccharide transfer activity for converting an α-1,4 bond to an α-1,6 bond in the process for producing the processed meat food or the processed fishery food.2010-06-03
20100136168SUPPLEMENTED FRUIT OR VEGETABLE PRODUCT - Compositions of supplemented fruit and/or vegetable products as well as methods for making the same are provided. Certain embodiments include supplements of macronutrients and/or micronutrients. Also provided are processes of manufacture and business methods relating to the compositions disclosed.2010-06-03
20100136169NOVEL ASPARAGINASES AND USES THEREOF - The present invention relates to an asparaginase having the width of the pH activity profile which is at least 3.5. Furthermore the invention relates to newly identified asparaginase polypeptide according to any one of SEQ ID NO: 2 or SEQ ID NO: 4 and to variants thereof and to polynucleotide sequences that encode such novel asparaginase variants. Furthermore the invention relates to the use of these novel asparaginase variants in industrial processes.2010-06-03
20100136170Procedure for Extruder Cooking of Animal Feed Without Using a Dryer - Procedure for production of dry feeds for animals without using a drier by adding 25% of a digestible starchy or another extrudable powdery “glue” to a continuous extruder cooker, where it is cooked at high pressure and temperature until sufficient gelatinization and thermo-plastic condition is achieved. The glue product is then carried through a vacuum zone, in which the sudden pressure drop causes evaporation and temperature drop, so that the moisture content in the glue product drops. After the vacuum zone 75% of an unheated primary feed mixture is added to the glue product, and the two products are mixed. After the mixing zone the finished product is carried through a die and cut to pellets by a rotating knife.2010-06-03
20100136171GOOD TASTING FOOD PRODUCT CONTAINING AN AGENT FOR REDUCING CARBOHYDRATE UPTAKE; AND COMPOSITIONS CONTAINING SUCH AN AGENT - The present invention relates to good tasting food products that contain an agent or agents which avoid that taste-essential ingredients having an adverse effect, when digested or when taken up in the system of the consumer, can perform their adverse effects. The said adverse effect is especially an adverse effect on human health. In addition, the present invention relates to particular compounds or compositions that can be used for the directed removal of such adverse components of foods (including drinks).2010-06-03
20100136172PROCESS FOR THE PREPARATION OF ANGIOGENIN - The invention provides a process for the preparation of an angiogenin-enriched fraction from a milk product, the process comprising contacting the milk product with a cation exchange resin and eluting the angiogenin-enriched fraction from the cation exchange resin with a mobile phase. The invention also provides angiogenin-enriched fractions produced by process and food products, neutraceuticals and pharmaceutical comprising such angiogenin.2010-06-03
20100136173PROTEIN CONCENTRATES AND ISOLATES, AND PROCESSES FOR THE PRODUCTION THEREOF - Protein concentrates and protein isolates, in addition to processes for the production of protein concentrates and protein isolates, are disclosed. In particular, the disclosure relates to the removal of fiber from an oilseed meal using low g-force centrifugation.2010-06-03
20100136174DAIRY CREAM PRODUCTS & METHODS - A dairy cream related food product comprising dairy cream and a quantity of what is designated a “mother blend”. The mother blend is partially made up of a liquid component of water and/or MFGM buttermilk, and/or whey which comprises the mother blend liquid component. The other part of the mother blend is a quantity of a hydrocolloid fiber ingredient that is intimately mixed in the process with the mother blend liquid. By varying the quantities of the ingredients and also in some instances adding additional ingredients to the end product, variations of the dairy cream related food products are created.2010-06-03
20100136175CLEAR FLAVOR MICROEMULSIONS COMPRISING SUGAR ESTERS OF FATTY ACIDS - Formulations of clear, thermodynamically stable and concentrated oil-in-water microemulsions are disclosed, comprising a surfactant system which is formed of a sugar ester of a fatty acid together with lecithin, as well as their use for the flavoring of clear beverages.2010-06-03
20100136176RUMINANT FEEDS CONTAINING pH-ADJUSTED EDIBLE BYPRODUCTS AND HIGH DIGESTIVE EFFICIENCY GRAINS - Improved ruminant feeds are provided which include a pH-adjusted first ingredient selected from the group consisting of ruminant-edible, initially low pH commercial byproducts and initially low pH grain or forage-derived products, combined with a second ingredient comprising a high digestive efficiency feed grain such as flaked corn. An improved process (2010-06-03
20100136177PROCESS FOR THE MANUFACTURE OF A POWDER CONTAINING CAROTENOIDS - Process for the manufacture of a powder containing one or more carotenoids, powder obtainable by said process and food composition containing said powder.2010-06-03
20100136178CAPSULE CONTAINING HYDRO-SOLUBLE OR INFUSION PRODUCTS TO OBTAIN HOT BEVERAGES - A capsule containing hydro-soluble (2010-06-03
20100136179POUCHED LIQUID FOOD PRODUCT - A pouched liquid food product from which a delicious dish can be cooked with a microwave oven without the color, smell, texture and the like of the food ingredients being harmed has a pouch having a zipper portion and a steam venting mechanism. The pouch is filled with a liquid food and sealed, and a liquid substance in the liquid food has a viscosity at 60° C. of 0.1 to 10 Pa·s. The relationship between the liquid food and a solid ingredient satisfies at least one of the following conditions (a) to (d): 2010-06-03
20100136180METHOD AND APPARATUS FOR MAKING CENTRE-FILLED SHAPED FOOD PRODUCTS - The present invention relates to an apparatus for making a food product (2010-06-03
20100136181PARTICULATE FOOD COMPONENT - The invention relates to a particulate food constituent comprising a filling and a coating, characterised in that the filling is a food preparation which is free-flowing at room temperature and selected from the group consisting of fruit preparations, other preparations and mixtures thereof, and in that the coating consists of a layer consisting of a constituent selected from the group of suitable cocoa products, chocolate products, and hydrophobic food ingredients, especially optionally aromatised and/or dyed fats or fatty materials that have a minimum fat content of 80%, or mixtures thereof. The average particle diameter of the food constituent is between 6 and 18 mm, preferably between 8 and 11 nm.2010-06-03
20100136182FAT FILLING OR CHOCOLATE SUBSTITUTE FOR CEREAL-BASED BAKERY PRODUCTS - The invention relates to a butterfat filling or imitation chocolate with a reduced butterfat and/or sugar content, and cereal cooking products comprising one such butterfat filling or imitation chocolate. The inventive butterfat filling or imitation chocolate consists of a suspension of solid particles in a continuous fat phase, said suspension comprising less than 33% butterfat and between 3 and 40% raw starch.2010-06-03
20100136183METHOD FOR PREPARATION OF A CREAMY MILK BASED BEVERAGE FROM A CAPSULE AND KIT FOR SUCH PREPARATION - Method for the preparation of a foamy or creamy instant drink, wherein at least two capsules are sequentially injected with cold water to produce an instant milk-based drink, the first capsule to be injected comprising milk powder, a creamer component and sugar, the second capsule comprising milk powder, a soluble main flavour component and sugar.2010-06-03
20100136184CONFECTIONERY COMPOSITION, ARTICLE, METHOD, AND APPARATUS - A dough-like confectionery material contains a solid particulate, a liquid, and a diffusion controller. The dough-like confectionery material is an effective replacement for panned coatings, and it can be applied to an edible substrate, such as candy or chewing gum to form a layered confection. Methods and apparatus for forming layered confections are also described.2010-06-03
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