22nd week of 2012 patent applcation highlights part 44 |
Patent application number | Title | Published |
20120136021 | OXIDATION-STABILIZED TAMPER-RESISTANT DOSAGE FORM - A thermoformed pharmaceutical dosage form having a breaking strength of at least 300 N,
| 2012-05-31 |
20120136023 | Inhibitors of HIV Replication - The present invention relates to novel 2,3,4-substituted 5,6,7,8-tetrahydro[1]benzothieno[2,3-b]pyridine compounds and pharmaceutically acceptable salts thereof, to compositions containing such compounds and to the use of such compounds as inhibitors of HIV replication. | 2012-05-31 |
20120136024 | 3-Substituted-2-(arlyalkyl)-1-azabicycloalkanes and Methods of Use Thereof - The present invention relates to 3-substituted-2-(arylalkyl)-1-azabicycloalkanes, methods of preparing the compounds and methods of treatment using the compounds. The azabicycloalkanes generally are azabicycloheptanes, azabicyclooctanes, or azabicyclononanes. The aryl group in the arylalkyl moiety is a 5- or 6-membered ring heteroaromatic, preferably 3-pyridinyl and 5-pyrimidinyl moieties, and the alkyl group is typically a C | 2012-05-31 |
20120136025 | QUINOLONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF - Disclosed are quinolone derivatives characterized in that these have lower alkyl, cycloalkyl or the like at the 1-position; —N(R | 2012-05-31 |
20120136026 | 5-MEMBERED HETEROCYCLIC COMPOUND CYCLOPENTA[C]PYRROLYLALKYLCARBAMATE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF - The invention relates to compounds of the general formula (I) where: R | 2012-05-31 |
20120136027 | Phenyl Ethynyl Derivatives As Hepatitis C Virus Inhibitors - Inhibitors of HCV replication of formula I | 2012-05-31 |
20120136028 | Methods Of Diminishing Co-Abuse Potential - Methods of diminishing or eliminating the co-abuse of a methylphenidate drug comprising identifying a patient or patient group suspected or likely to abuse said methylphenidate drug in combination with a substance known or suspected to give rise to l-ethylphenidate or psychotropic effect when ingested in the combination and making available to said patent or patient group said methylphenidate drug substantially free of l-threo methylphenidate. | 2012-05-31 |
20120136029 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE OF 2-ARYL PYRIDYLAZOLES - A 2-aryl-pyridylazole compound and derivatives useful in slowing the growth of cancer cells are disclosed. Also disclosed are methods of synthesizing the compound, methods of using pharmaceutical compositions containing the compound as an ingredient to slow the growth of cancer cells, and methods of treating cancer patients with pharmaceutical compositions containing the compound as an ingredient. | 2012-05-31 |
20120136030 | COMBINATIONS OF MEK INHIBITORS AND RAF KINASE INHIBITORS AND USES THEREOF - This invention concerns combinations of inhibitors of MEK, Raf protein kinases, and other kinases including VEGFR1-3 and PDGFR-β. This invention also concerns pharmaceutical compositions comprising the compounds described herein and methods of use of the compounds and compositions described herein, including the use in the treatment and/or prevention of cancer and other hyperproliferative disorders. | 2012-05-31 |
20120136031 | P38MAP KINASE INHIBITOR - The present invention relates to a compound of formula (I): | 2012-05-31 |
20120136032 | Fungicidal Active Substance Combinations Containing Trifloxystrobin - What are described are novel active compound combinations comprising a known oxime ether derivative (trifloxystrobin) and imidacloprid, which combinations are highly suitable for controlling phytopathogenic fungi and insects. | 2012-05-31 |
20120136033 | Small Molecule Antagonists of Phosphatidylinositol-3,4,5-Triphosphate (PIP3) and Uses Thereof - Disclosed are a new class of non-lipid small molecule inhibitors which interfere with the interaction between PIP3 and pleckstrin homology domains. These molecules target a broad range of PIP3-dependent signaling events in vitro and exert significant anti-tumor activity in vivo. The small molecule inhibitors of the invention can be used alone or together with tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) or other cancer medicament to treat cancer. Small molecule inhibitors of the invention act synergistically in combination with TRAIL in treating cancer. Pharmaceutical compositions and methods for treating cancer are provided. | 2012-05-31 |
20120136034 | FATTY ACIDS AS ANTI-INFLAMMATORY AGENTS - Compounds of formula I and their metabolites are potent mediators of an inflammatory response: (I) where a, b, c, d, e, f, V, W, X, Y, R | 2012-05-31 |
20120136035 | 4-(1-(3-(HYDROXYMETHYL)-2-METHYLPHENYL)ETHYL)-1H-IMIDAZOLE-2(3H)-THIONE - Disclosed herein is 4-(1-(3-(hydroxymethyl)-2-methylphenyl)ethyl)-1H-imidazole-2(3H)-thione and methods of using the compound to treat chronic pain. | 2012-05-31 |
20120136036 | ESTER PRO-DRUGS OF [3-(1-(1H-IMIDAZOL-4-YL)ETHYL)-2-METHYLPHENYL] METHANOL FOR TREATING SKIN DISEASES AND CONDITIONS - The present invention relates to method for treating skin diseases and skin conditions in a subject in need of such treatment, which comprises administering a therapeutically effective amount of a composition comprising ester pro-drugs of [3-(1-(1H-imidazol-4-yl)ethyl)-2-methylphenyl]methanol, or enantiomers thereof, pharmaceutical compositions containing them and their use as pharmaceuticals. | 2012-05-31 |
20120136037 | DEUTERIUM-ENRICHED RUBOXISTAURIN - The present application describes deuterium-enriched ruboxistaurin, pharmaceutically acceptable salt forms thereof, and methods of treating using the same. | 2012-05-31 |
20120136038 | Novel Polymorphs Of Azabicyclohexane - The invention provides polymorphic crystalline forms of acid addition salts of (±)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane designated as polymorph form A, polymorph form B and polymorph form C, where polymorph form A is more thermodynamically stable than the other forms, methods for preparing and using such polymorph forms and pharmaceutical compositions containing such polymorph forms. | 2012-05-31 |
20120136039 | SINGLE NUCLEOTIDE POLYMORPHISM (SNP) TARGETING THERAPIES FOR THE TREATMENT OF HUNTINGTON'S DISEASE - The present invention relates to the discovery of (SNPs) significantly associated with Huntington's disease (HD). The present invention utilizes RNA silencing technology (e.g. RNAi) against such SNPs optimally combined with select additional SNP targeting silencing agents, thereby resulting in an effective treatment of significantly-sized patient populations. Silencing agents having enhanced discriminatory properties are also featured. | 2012-05-31 |
20120136040 | HYBRID INTERFERING RNA - The invention relates to a hybrid interfering RNA molecule comprising a duplex RNA and a single stranded DNA molecule and its use in the ablation of mRNA and in polymerase chain reactions. | 2012-05-31 |
20120136041 | Treating Ocular Diseases Using Peroxisome Proliferator-Activated Receptor Delta Antagonists - The present invention provides novel agents, expression constructs, compositions and methods useful for treating an ocular disease associated with unwanted PPARδ activity through the modulation of PPARδ expression. The PPARδ interference RNA (iRNA) agents, expression constructs encoding such agents, and compositions comprising such agents or constructs are directed against RNA molecules encoding PPARδ. The methods comprise treating an ocular disease associated with unwanted PPARδ activity in a patient in need thereof by administering an effective amount of a pharmaceutical composition comprising a PPARδ iRNA agent or expression construct encoding such agent to the patient to reduce a symptom associated with unwanted PPARδ activity in the patient. | 2012-05-31 |
20120136042 | CARBOHYDRATE CONJUGATES AS DELIVERY AGENTS FOR OLIGONUCLEOTIDES - The present invention provides iRNA agents comprising at least one subunit of the formula (I): | 2012-05-31 |
20120136043 | ANTISENSE OLIGONUCLEOTIDES (ODN) AGAINST SMAD7 AND USES THEREOF IN MEDICAL FIELD - The invention relates to antisense oligonucleotidic sequences (ODN) against Smad7 suitably modified, and their uses in medical field as therapeutic biological agents, in particular in the treatment of chronic inflammatory bowel disease, such as Crohn's disease and ulcerative colitis. | 2012-05-31 |
20120136044 | Compositions And Methods Of Inhibiting NADPH Oxidase Expression - The invention relates to one or more inhibitors, in particular siRNAs, which down-regulate the expression of a NOX gene selected from the group consisting of NOX4, NOX1, NOX2 (gp91phox, CYBB), NOX5, DUOX2, NOXO1, NOXA1 and NOXA2 (p67phox). The invention also relates to a pharmaceutical composition comprising the compound, or a vector capable of expressing the compound, and a pharmaceutically acceptable carrier. The present invention also contemplates a method of treating or preventing the incidence or severity of various diseases or conditions associated with NOX gene comprising administering to the patient the pharmaceutical composition in a therapeutically effective dose so as to thereby treat the patient. | 2012-05-31 |
20120136045 | SCREENING FOR COMPOUNDS THAT MODULATE GPR3-MEDIATED BETA-ARRESTIN SIGNALING AND AMYLOID BETA PEPTIDE GENERATION - The invention relates to the field of disorders of the peripheral or central nervous system, in particular, Alzheimer's disease, and the prevention and/or treatment thereof. In particular, the invention relates to the screening of compounds that modulate GPR3 activity and/or beta-arrestin signaling in a mammalian cell and, in particular, compounds that reduce the formation of amyloid beta peptides. The invention also relates to inhibiting agents targeting beta-arrestin signaling and pharmaceutical compositions thereof, and their use in therapeutic applications of those disorders. | 2012-05-31 |
20120136046 | METHOD OF TREATING AGE RELATED DISORDERS - The present invention relates to the use of fujimycin for the treatment of a disorder related to the chronological and/or replicative life-span of a cell, and to methods for increasing the replicative life span of a cell, said method comprising disrupting the function of a polynucleotide or gene encoding a polypeptide comprising SEQ ID No: 1, 3 or 5. | 2012-05-31 |
20120136047 | NEUROPROTECTIVE COMPOSITIONS AND METHODS - This disclosure concerns novel methods for preventing or treating neurological or neurodegenerative diseases or disorders by using kombo butter acid enriched extracts derived from the seeds of African nutmeg, the main active compounds isolated from the extracts, namely sargaquinoic acid, sargachromenol, and sargahydroquinoic acid, or synthetic analogs or derivatives thereof, as neuroprotective agents. The methods for preparing the kombo butter or kombo butter acid extracts and the methods for isolating and purifying the active compounds and for preparing their acetylated derivatives are also described. | 2012-05-31 |
20120136048 | TOPICAL, PERIOCULAR, OR INTRAOCULAR USE OF TOCOTRIENOLS FOR THE TREATMENT OF OPHTHALMIC DISEASES - A method for preventing, reducing, ameliorating or treating ophthalmic disorders associated with neurodegenerative diseases or trauma, comprising the topical, periocular, or intraocular application of an ophthalmic formulation comprising a therapeutically effective amount of one or more ophthalmic agents selected from the group consisting of alpha-tocotrienol, beta-tocotrienol, gamma-tocotrienol, delta-tocotrienol, or esters or mixtures thereof is disclosed. Use of tocotrienols for the prevention, reduction, amelioration or treatment of ophthalmic disorders that are, or that are associated with, mitochondrial diseases is also discussed. Topical ophthalmic formulations comprising tocotrienols are also discussed. | 2012-05-31 |
20120136049 | ANTIBACTERIAL AGENT - The present invention provides an epigallocatechin gallate derivative (EGCG derivative) that has excellent safety and antibacterial properties. An epigallocatechin gallate derivative represented by the following chemical formula (1), an isomer thereof, or a salt thereof is used as an antibacterial agent. In the formula, R | 2012-05-31 |
20120136050 | USE OF A MELATONIN AGONIST FOR THE TREATMENT OF SLEEP DISORDERS INCLUDING PRIMARY INSOMNIA - Embodiments of the invention include the treatment of a sleep disorder comprising the administration of N-[[(1R,2R)-2-(2,3-dihydro-1-benzofuran-4-yl)cycloproply]methyl]propanamide or a salt, stereoisomer, solvate, or hydrate thereof, in amorphous or crystalline form. | 2012-05-31 |
20120136051 | RHEOLOGY MODIFIED LOW FOAMING LIQUID ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF - The present disclosure relates to rheology modified, low foaming aqueous antimicrobial compositions. The compositions are phase stable under acidic conditions, and do not need to be rinsed from the surface to which they are applied. The present disclosure further relates to methods of use thereof. | 2012-05-31 |
20120136052 | SUBSTITUTED ACYLANILIDES AND METHODS OF USE THEREOF - This invention provides SARM compounds and uses thereof in treating a variety of diseases or conditions in a subject, including, inter alia, a muscle wasting disease and/or disorder or a bone-related disease and/or disorder. | 2012-05-31 |
20120136053 | COPEPOD OIL COMPOSITION, FORMULATIONS COMPRISING THE OIL COMPOSITION, AND THE USE THEREOF TO REDUCE ACCUMULATION OF VISCERAL FAT, IMPROVE GLUCOSE TOLERANCE, AND PREVENT OR TREAT OBESITY RELATED DISEASES AND DISORDERS - This invention relates to an oil composition, preferably obtained from a copepod, and the use thereof to reduce accumulation of visceral fat and counteract impairment of heart function caused by obesity inducing Western diets. The oil composition of the present invention can thus be used to reduce abdominal obesity and improve glucose tolerance and thus to reduce the risk of obesity related diseases such as but not limited to type 2 diabetes or cardiovascular disease, or to prevent or treat such diseases. | 2012-05-31 |
20120136054 | MATERIALS AND METHODS FOR MEASURING NITRIC OXIDE LEVELS IN BIOLOGICAL FLUIDS - The subject invention presides novel devices and methods for the measurement of nitric oxide in biological samples, including wound fluid samples. These advantageous devices and methods can be used for clinicians to monitor the wound's nitric oxide metabolism and/or response to treatment. | 2012-05-31 |
20120136055 | SEMI-SOLID COMPOSITIONS AND PHARMACEUTICAL PRODUCTS - This invention relates to semi-solid compositions and semi-solid pharmaceutical products for use in the photodynamic treatment (PDT) of cancer, pre-cancerous conditions and non-cancerous conditions in the female reproductive system, the anus and the penis, preferably for use in PDT of endometrial, cervical, vulvar, vaginal, anal and penile dysplasia and HPV infections of the uterus, cervix, the vulva, the vagina, the anus and the penis. The semi-solid compositions and pharmaceutical products comprise an active ingredient which is 5-aminolevulinic acid (5-ALA) or a precursor or derivative of 5-ALA or pharmaceutically acceptable salts thereof. The invention relates further to methods of PDT of cancer, pre-cancerous conditions and non-cancerous conditions in the female reproductive system, the anus and the penis, wherein said semi-solid compositions and pharmaceutical products are used. | 2012-05-31 |
20120136056 | Pesticidal Compositions For Insects And Arthropods - The present invention provides an insect or arthropod pesticidal composition. The composition includes active ingredients having a mixture of fatty acids, each of the fatty acids having a straight carbon chain from 6 to 12 carbon atoms long. The fatty acid mixture includes a first fatty acid molecule having a straight carbon chain from 6 to 8 carbon atoms long, and a carboxylic acid group. The fatty acid mixture also includes a second fatty acid molecule having a straight carbon chain from 8 to 12 carbon atoms long, and a carboxylic acid group. The composition also includes a carrier that promotes adherence or absorption or transport across the surface of insects or arthropods to effect their incapacitation or death. | 2012-05-31 |
20120136057 | HYDROXY FATTY ACID COMPOUNDS AND USES THEREOF FOR DISEASE TREATMENT AND DIAGNOSIS - A compound of formula (I): wherein R represents a hydroxy substituted C | 2012-05-31 |
20120136058 | Method For Increasing The Solubility Of Methionine By Mineral Addition And Acid Treatment - The present invention relates to a method for enhancing the solubility of methionine. More particularly, the present invention relates to a method for increasing the solubility of methionine, in which mineral and sulfuric acid are added at an appropriate ratio to enhance the methionine solubility, thereby overcoming the problem of low solubility of methionine in water. | 2012-05-31 |
20120136059 | COMBINATIONS OF ADAPALENE AND BENZOYL PEROXIDE FOR TREATING ACNE LESIONS - Adapalene or a pharmaceutically acceptable salt thereof formulated into a pharmaceutical composition is useful for reducing the number of acne lesions, via daily topical application, in combination or in association with benzoyl peroxide (BPO); such treatment may be via administration of a pharmaceutical composition combining adapalene and BPO or by a concomitant application of two pharmaceutical compositions, one containing adapalene and the other containing BPO. | 2012-05-31 |
20120136060 | IMMEDIATE RELEASE AND SUSTAINED RELEASE IBUPROFEN DOSING REGIMEN - A method of administering non-steroidal-anti-inflammatory drugs, in particular propionic acid derivatives such as ibuprofen, is provided. The inventive dosage forms provide an initial release of the NSAID and a second sustained release of NSAID, preferably in a single dosing step. | 2012-05-31 |
20120136061 | LYCOPENE AND RESVERATROL COMPOSITIONS FOR NK CELL ACTIVATION RESULTING IN ANTI-NEOPLASTIC EFFECT - A carotenoid and a terpenoid in therapeutically-effective amounts is disclosed such that, upon ingestion in one preparation, or in two separated preparations, simultaneous or sequentially, and upon metabolism, the activity of natural killer (NK) cells is elevated. Specifically, the composition comprises lycopene and resveratrol in the range of 1:10 to 10:1 by molar; more preferably 1:1 to 3:1 by molar, and most preferably at 3:1. Alternatively, the preferred ratio may be expressed as 1:4 to 25:1 by weight; more preferably 2½:1 to 7½:1 by weight, and most preferably at 7½:1. The composition may be formulated for oral intake as a pharmaceutical, dietary supplement or food product and provided in therapeutically effective amounts to a mammal, preferably in a dosage of about 3.5 mg per day per 20 g of a mammalian body mass in a ratio of 2½:1 by weight, which can be translated to about 400 mg to 1000 mg per day for a typical human in need of elevating NK cell activity. Preferably, the therapeutically-effective aspect of the composition includes its metabolically-producing agents, prodrugs, metabolites or intermediate compounds useful in triggering NK cells into cytotoxic or cytolytic response. | 2012-05-31 |
20120136062 | NOVEL COMPLEX FOR TREATMENT AND/OR PROPHYLAXIS OF PARASITIC INFECTIONS - Disclosed are complexes of an antipneumocystic compound and an antimalarial compound, processes for their preparation, pharmaceutical compositions and methods of using said complexes or compositions for the treatment and/or prophylaxis of parasitic infections. | 2012-05-31 |
20120136063 | FTY720-DERIVED ANTICANCER AGENTS - A number of FTY720-derived compounds with antitumor activity are described. These compounds include the compounds of formula I: | 2012-05-31 |
20120136064 | METHODS FOR SCREENING TO IDENTIFY THERAPEUTIC AGENTS FOR ALZHEIMER'S DISEASE AND USE THEREOF - Methods for treating Alzheimer's Disease (AD) using modulators of lysosomal activity are described herein. More particularly, methods described herein relate to the use and application of compounds or agents that enhance lysosomal activity for the treatment of AD. In a particular aspect, the method relates to the use and application of compounds or agents that increase the pH of the lysosome and/or increase the overall activity of lysosomal proteases for the treatment of AD. Also described herein are methods and assays for screening to identify compounds or agents that increase the pH of the lysosome and/or increase the overall activity of lysosomal proteases for the treatment of AD. | 2012-05-31 |
20120136065 | Treatment of CNS Disorders with trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-1-Napthalenamine - Treatment of CNS disorders with (1R,4S)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine; and (1S,4R)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is disclosed. A process for preparing 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is also disclosed. The process includes the preparation of all four isomers of N-[4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]formamide, which are also useful. | 2012-05-31 |
20120136066 | Glomerulonephritis Treatment - A compound of formula (I) R-L-CO—X (I) (wherein R is a C | 2012-05-31 |
20120136067 | OIL/WATER ACTIVE INGREDIENT EMULSION CONTAINING UV FILTER - A cosmetic oil/water emulsion comprising a) 2-ethylhexyl-2-cyano-3,3-diphenylacrylate (INCI: Octocrylene), b) 4-(tert.-butyl)-4′-methoxydibenzoyl methane (INCI: Butylmethoxydibenzoyl methane), c) licorice extract or licochalcone A. | 2012-05-31 |
20120136068 | AMELIORANT FOR RENAL INSUFFICIENCY - The present invention relates to an agent for improving renal dysfunction comprising as an active ingredient a compound represented by the following formula (1): | 2012-05-31 |
20120136069 | Alcoholic Pump Foam - An alcoholic foam composition, which can be dispensed as a foam via a pump-foam system contains a) at least 52 to ≦99 wt % of an alcohol or mixture of alcohols, b) a surfactant or a surfactant mixture, c) at least one polyalkylene glycol, d) optionally, at least one foam stabilizer, e) optionally, at least one member selected from the group consisting of cosmetic auxiliaries, adjuvants, active ingredients, and mixtures thereof, and f) optionally water. The surface tension of component b) lies in the range of ±15 dyn/cm of the surface tension of component a) or corresponds to the surface tension of component a), and the sum of components a) to f) is 100 wt % relative to the total quantity of the foam composition. | 2012-05-31 |
20120136070 | KETAL ESTERS OF ANHYDROPENTITOLS AND USES THEREOF - The present disclosure relates to the preparation of ketal compounds from anhydropentitols and oxocarboxylates; derivatives, homopolymers, and copolymers thereof; and various compositions, formulations, and articles derived therefrom. | 2012-05-31 |
20120136071 | Medicinal Cream For Diaper Rash And A Process To Make It - The present invention relates to a composition for treating diaper rash along with skin rejuvenation. More particularly, the present invention relates to a pharmaceutical cream comprising a biopolymer, and an anti diaper rash active ingredient. It discloses a composition for treating diaper rash along with skin rejuvenation containing a) a biopolymer in the form of chitosan, b) a combination of active ingredients used in treating diaper rash, c) a cream base containing primary and secondary emulsifiers, waxy materials, co-solvents, acids, preservatives, buffering agents, anti oxidants, chelating agents, and humectants, and d) water. The active ingredients, namely chitosan, and diaper rash agents, are incorporated in cream base for use in treating diaper rash. | 2012-05-31 |
20120136072 | Sulfoalkyl Ether Cyclodextrin Compositions and Methods of Preparation Thereof - A particulate SAE-CD composition is provided. The SAE-CD composition has an advantageous combination of physical properties not found in known solid forms of SAE-CD. In particular, the SAE-CD composition possesses an advantageous physicochemical and morphological property profile such that it can be tailored to particular uses. The SAE-CD composition of the invention has improved flow and dissolution performance as compared to known compositions of SAE-CD. | 2012-05-31 |
20120136073 | Amine-Containing Transfection Reagents and methods for making and using same - There are provided for herein novel amine-containing transfection compounds and methods for making and using same. The compounds are generally obtained by reacting a primary amine with an unsaturated compound. Transfection complexes made using the amine-containing transfection compounds in combination with additional compounds to encapsulate biologically active agents such as nucleic acids are also provided for herein. Methods of using the transfection complexes for the in vivo or in vitro delivery of biologically active agents are also described. The transfection complexes of the present invention are highly potent, thereby allowing effective modulation of a biological activity at relatively low doses compared to analogous transfection compounds known in the art. | 2012-05-31 |
20120136074 | SYSTEMS AND METHODS EMPLOYING LOW MOLECULAR WEIGHT GELATORS FOR CRUDE OIL, PETROLEUM PRODUCT OR CHEMICAL SPILL CONTAINMENT AND REMEDIATION - Low molecular weight gelators, methods of making such gelators, organogels comprising such gelators and systems and methods of using such gelators for the containment and/or remediation of a release and/or spill of a crude oil, a petroleum product and/or a chemical is described. In exemplary systems and methods, gels and/or emulsions formed from the combination and/or contact of such gelators and at least one of a crude oil, a petroleum product and a chemical from a release and/or spill into the environment can be used to recover these oils or chemicals while allowing the gelators to be recovered and reused to clean up or contain additional crude oil, petroleum products or chemicals. | 2012-05-31 |
20120136075 | SYSTEM AND PROCESS FOR FISCHER-TROPSCH CONVERSION - A system for converting carbon monoxide and hydrogen gas into C2+ hydrocarbons including at least one high shear mixing device comprising at least one rotor and at least one stator separated by a shear gap, wherein the high shear mixing device is capable of producing a tip speed of the at least one rotor of greater than 22.9 m/s (4,500 ft/min), and a pump configured for delivering a fluid stream comprising liquid medium to the high shear mixing device. | 2012-05-31 |
20120136076 | MULTI-STAGE ADIABATIC METHOD FOR PERFORMING THE FISCHER-TROPSCH SYNTHESIS - The present invention relates to a multistage adiabatic process for performing the Fischer-Tropsch synthesis at low temperatures, in which the synthesis is performed in 5 to 40 series-connected reaction zones under adiabatic conditions. | 2012-05-31 |
20120136077 | FLUORINATED COPOLYMERS, MEMBRANES PREPARED USING THE LATTER AND FUEL CELL DEVICE INCLUDING SAID MEMBRANES - A fluorinated copolymer including at least one recurrent unit of the following formula (I): | 2012-05-31 |
20120136078 | ORGANIC POLYMERIC PARTICLES, PAPER COATING COMPOSITIONS, AND METHODS - Embodiments of the present disclosure include organic polymeric particles, paper coating compositions, coated paper, and methods of forming coated paper with the paper coating compositions. The embodiments of the organic polymeric particle include an organic hydrophilic polymer with a unit for hydrogen bonding, and a hollow porous structure that comprises an organic polymer that at least partially surrounds the organic hydrophilic polymer, where the hollow porous structure has a pore surface area greater than 1 percent of a total theoretical exterior surface area of the hollow porous structure and the organic hydrophilic polymer and the hollow porous structure give the organic polymeric particle a void volume fraction of 40 percent to 85 percent. | 2012-05-31 |
20120136079 | MODIFIED HYBRID SILICA AEROGELS - Disclosed and claimed herein are hybrid silica aerogels containing non-polymeric, functional organic materials covalently bonded at one or both ends to the silica network of the aerogels through a C—Si bond between a carbon atom of the organic material and a silicon atom of the aerogel network. Methods of their preparation are also disclosed. | 2012-05-31 |
20120136080 | POROUS PARTICLES WITH IMPROVED FILTERING PERFORMANCE - A method of manufacturing porous polymer particles with improved filterability is described. One or more first water phases are formed comprising an anionic hydrocolloid with a mass-per-charge value of less than 600 and a relatively minor amount, compared to the anionic hydrocolloid, of at least one of a nonionic, cationic, zwitterionic, or weakly anionic water soluble or dispersible polymer, where the weakly anionic water soluble or dispersible polymer has a mass-per-charge value of larger than 600. A water-in-oil emulsion is formed by dispersing the one or more first water phases into an organic phase comprising at least one of either (i) preformed polymer dissolved in an organic solvent or (ii) polymerizable monomers, and homogenizing. A water-in-oil-in-water multiple emulsion is formed by dispersing the water-in-oil emulsion into a second water phase containing a stabilizing agent and homogenizing. The organic solvent is removed to precipitate the preformed polymer, or the polymerizable monomers are polymerized, to obtain a dispersion of porous polymer particles in an external aqueous phase, wherein individual porous particles each comprise a continuous polymer phase and internal pores containing an internal aqueous phase. The dispersion of porous polymer particles is filtered to remove the external aqueous phase. The method enables increased filtration rates of porous polymer particle dispersions containing water in the pores. | 2012-05-31 |
20120136081 | Resorbable Polyurethane Wound Cover - The present invention relates to a biocompatible, resorbable polyurethane foam wound cover with open pores and an adjustable resorption rate having improved properties when used on skin or connective tissue wounds as well as a method of production of such a polyurethane foam wound cover. | 2012-05-31 |
20120136082 | BINDING AGENTS BASED ON HIGHLY BRANCHED POLYOLEFINS COMPRISING SILANE GROUPS - The invention relates to highly branched polymers (P) comprising at least one silane group, wherein at least one silicon atom carries a hydrolysable group of the general formula (I): R | 2012-05-31 |
20120136083 | Systems And Methods For Stabilization Of A Phylon Article - A manufacturing method, within a modularized manufacturing environment for stabilizing a phylon article that is produced utilizing a heat press, is provided. Initially, the method includes immersing a phylon article in a first tank, with a fluid disposed therein, and withdrawing the phylon article from exposure with the fluid. Typically, the midsole is heated from its production with the heat press when it is placed into the first tank. The immersion in the first tank acts to cool the phylon article, thereby stabilizing the heated phylon. The phylon article may be next placed in a second tank, with a fluid disposed therein, and withdrawn from exposure with the fluid. The fluid of the first tank may reside at a temperature comparable to or higher than the temperature of the fluid of the second tank. Recursively exposing the heated phylon article to the fluid of the tanks incrementally decreases the volume of the article. | 2012-05-31 |
20120136084 | EXTRUSION OF POLYURETHANE COMPOSITE MATERIALS - Methods of extruding polyurethane composite materials are described. One method includes introducing at least one polyol and inorganic filler to a first conveying section of the extruder, transferring the at least one polyol and inorganic filler to a first mixing section of an extruder, mixing the at least one polyol and the inorganic filler in the first mixing section, transferring the mixed at least one polyol and inorganic filler to a second conveying section of the extruder, introducing a di- or poly-isocyanate to the second conveying section, transferring the mixed at least one polyol and inorganic filler and the di- or poly-isocyanate to a second mixing section, mixing the mixed at least one polyol and inorganic filler with the di- or poly-isocyanate in the second mixing section of the extruder to provide a composite mixture, and transferring the composite mixture to an output end of the extruder. Other related methods are also described. | 2012-05-31 |
20120136085 | POLYURETHANE FOAM AND PNEUMATIC TIRE - A polyurethane foam which is obtained by a reaction between a diol component and a diisocyanate component, with the diol component being a mixture of a polyether-based diol and a polyester-based diol, and a pneumatic tire to which the polyurethane foam is applied are provided. When a soft polyurethane foam is produced using a mixture of a polyether-based diol and a polyester-based diol as the diol component, and by varying the content of the expanding agent during the production process, and when the polyurethane foam is disposed in the cavity of a pneumatic tire, the polyurethane foam thus produced has an effect of reducing the resonance noise generated in the cavity of the tire and improving durability of the tire. | 2012-05-31 |
20120136086 | SILICONE-MODIFIED ADAMANTANE DERIVATIVE, PHOTO-RADICALLY CURABLE RESIN COMPOSITION, AND METHOD FOR PREPARING PHOTO-RADICALLY CURABLE RESIN COMPOSITION - There is disclosed a silicone-modified adamantane derivative represented by the following general formula (1), | 2012-05-31 |
20120136087 | PHOSPHORYLCHOLINE-BASED AMPHIPHILIC SILICONES FOR MEDICAL APPLICATIONS - Amphiphilic biomimetic phosphorylcholine-containing silicone compounds for use in both topical and internal applications as components in biomedical devices. The silicone compounds, which include zwitterionic phosphorylcholine groups, may be polymerizable or non-polymerizable. Specific examples of applications include use as active functional components in ophthalmic lenses, ophthalmic lens care solutions, liquid bandages, wound dressings, and lubricious and anti-thrombogenic coatings. | 2012-05-31 |
20120136088 | BIOCOMPATIBLE CERAMIC-POLYMER HYBRIDS AND CALCIUM PHOSPHATE POROUS BODY - A hydroxyapatite ceramic hybrid material, which includes a biodegradable polymer included in the pores in a hydroxyapatite ceramic structure, and a method thereof, and a calcium phosphate porous body, which is formed by an intertwining of fibrous calcium phosphates and includes a plurality of first pores formed where the fibrous calcium phosphates interconnect and plurality of equal diameter substantially spherical second pores with a larger inside diameter than the first pores, and a method thereof are provided. | 2012-05-31 |
20120136089 | Dental materials Using 2,2,4,4-Tetramethyl-1,3-Cyclobutandiol - Dental compositions and dental products having a resin derived from a cyclic diol such as 2,2,4,4-tetramethyl-1,3-cyclobutandiol. | 2012-05-31 |
20120136090 | FIBER WADDING FOR FILLING BONE DEFECTS - A fiber wadding for filling bone defects having a flocculent three-dimensional structure is disclosed. The fiber wadding includes a plurality of fibers that contain a biodegradable resin as a principal component and a siloxane. Outside diameter of the plurality of fibers of the wadding is from about 0.05 μm to about 30 μm. Bulk density of the fiber wadding is about 0.005-0.3 g/cm | 2012-05-31 |
20120136091 | METHOD OF MAKING HYDROXYARYL-FUNCTIONALIZED INTERPOLYMER BY FREE RADICAL INITIATED POLYMERIZATION - Radical polymerization techniques can be used to polymerize monomers that include a class of hydroxyaryl compounds so as to provide polymers that exhibit desirable properties including, but not limited to, reduced hysteresis. Compositions such as vulcanizates in which such polymers can be utilized and products such as tire components that incorporate and/or are manufactured from such compositions also are provided. | 2012-05-31 |
20120136092 | THERMOSETTABLE RESIN COMPOSITIONS - A reactive thermosettable resin composition including (a) at least one thermosetting resin; (b) at least one curing agent, and (c) optionally, at least one catalyst; wherein the curing agent (b) comprises a reactive inorganic cluster; and wherein the clusters are storage-stable inorganic clusters with reactive functional groups, such as amino groups; a process for preparing a thermoset product from the thermosettable composition. A composition of the reactive clusters as a curing agent and a thermosetting resin may be used to prepare thermoset products with improved thermo-mechanical behavior. | 2012-05-31 |
20120136093 | INTERCALATION AGENT FREE COMPOSITIONS USEFUL TO MAKE NANOCOMPOSITE POLYMERS - A two step method for preparing a filler composition, the filler composition useful to prepare a nanocomposite polymer and an epoxy nanocomposite coating. First, disperse a water dispersible filler material in a liquid comprising water, but without any added intercalation agent, to form a dispersion. Second, replace at least a portion of the water of the liquid with an organic solvent so that the water concentration of the liquid is less than six percent by weight to form the filler composition, the average size of at least one dimension of the filler material being less than two hundred nanometers upon examination by transmission electron microscopy of a representative freeze dried sample of the dispersion of the first step. A nanocomposite polymer can be prepared by mixing the filler composition with one or more polymer, polymer component, monomer or prepolymer to produce a polymer containing the filler composition. | 2012-05-31 |
20120136094 | VARNISH COMPOSITION, AND PRE-IMPREGNATED MANUFACTURE THEREOF - A varnish composition includes composition (A): an epoxy resin, composition (B): a hardener, composition (C): an accelerator, composition (D): phosphor-containing flame retardant, and composition (E): fillers, wherein composition (A) includes composition (A-1): phosphor-containing epoxy resin, phosphor-containing and silicon-containing epoxy resin, or a mixture thereof; composition (A-2): dicyclopentadiene epoxy resin; and composition (A-3): oxazolidone epoxy resin. | 2012-05-31 |
20120136095 | USE OF GRAFTED SMA COPOLYMERS IN LIQUID COMPOSITIONS - The subject of the invention is the use of a grafted copolymer derived from the grafting: of an SMA copolymer (II) derived from the copolymerization of at least two monomers, (i) the first monomer being chosen from styrene and its derivatives and (ii) the second monomer including at least one anhydride function, with (iii) M-R-X molecules (I) including at least one pattern (M) chosen from patterns (1) to (4): formula (I), with A=oxygen, sulfur or NH; and including at least one chemical function (X) chosen from among halogen, a primary or secondary amine function, an alcohol function, a thiol function, a carboxylic acid function or a derivative of said function and an epoxy function, the pattern (M) and said function (X) being connected by a rigid or flexible chain (R); used as the majority composition or additive of liquid compositions intended to be applied in or on sheets of paper or cardboard, onto hard surfaces, on leather or on textiles. | 2012-05-31 |
20120136096 | PROTECTION OF A DISPERSING AGENT DURING A GRINDING OPERATION - A method includes using a composition in the production of cement, the composition including at least one dispersing agent and at least one sacrificial molecule to partially or totally retain the properties of the dispersing agent; being either in the form of a liquid solution, or an emulsion or a suspension; the quantity of the sacrificial molecule in the composition representing at least 5% by mass of the mass of dispersing agent; and being introduced before or during the grinding of the clinker. | 2012-05-31 |
20120136097 | RESIN COMPOSITIONS COMPRISING LIGNIN DERIVATIVES - The present invention provides derivatives of native lignin having an ethoxy content of 0.45 mmol/g or greater. Surprisingly, it has been found that phenolic resins comprising derivatives of native lignin having ethoxy contents have acceptable performance characteristics such as bondstrength. | 2012-05-31 |
20120136098 | NEW TRIAZINE DERIVATIVE, ULTRAVIOLET ABSORBER, AND RESIN COMPOSITION - To provide a novel triazine-based compound exhibiting an ultraviolet blocking effect even in the long-wavelength region and being useful as an ultraviolet absorber with excellent light resistance, and to provide an ultraviolet absorber and a resin composition, which can maintain a long-wavelength ultraviolet-blocking effect for a long period of time. | 2012-05-31 |
20120136099 | COATING COMPOSITIONS CONTAINING LOW VOC COMPOUNDS - Coating compositions containing coalescents and a latex polymer, wherein the coalescent has a volatile organic content of less than about 50% and is dispersible in the coating composition. | 2012-05-31 |
20120136100 | THERMOPLASTIC ELASTOMER COMPOSITION - Provided is a thermoplastic elastomer composition, which includes a halogenated isoolefin/para-alkylstyrene copolymer rubber dispersed in a polyamide resin in order to improve the fatigue durability of a polyamide resin, while maintaining high flowability of the polyamide. A thermoplastic elastomer composition comprising a continuous phase composed of a modified polyamide resin (A) and a dispersed phase composed of a halogenated isoolefin/para-alkylstyrene copolymer rubber (B) is provided. The modified polyamide resin (A) is a resin obtained by melt-kneading 100 parts by weight of a polyamide resin (C) with not less than 0.05 part by weight and less than 3 parts by weight a compound (D), such as a monofunctional epoxy compound, capable of binding to a terminal amino group of the polyamide resin at a temperature not lower than the melting point of the polyamide resin (C). The composition can be used as an inner liner of a pneumatic tire. | 2012-05-31 |
20120136101 | ESTER-BASED PLASTICIZER - The present invention relates to a novel ester-based plasticizer, and, more particularly, to an ester plasticizer, which is synthesized by esterifying a polyhydric alcohol and an alkylene oxide with an aliphatic carboxylic acid or an aromatic carboxylic acid. When a polyvinylchloride resin is manufactured using the ester-based plasticizer, there are advantages in that products having a high plasticizing efficiency can be obtained and in that products having excellent physical properties, such as hardness, tensile strength, etc., can be obtained. | 2012-05-31 |
20120136102 | RUBBER COMPOSITION - This invention is to provide rubber composition having vulcanization retarding effect that is as same as or greater than that of DCBS, maintaining favorable working ability and providing excellent adherence to the metal, without the use of current vulcanization retarder, such as CTP that may generate problems of decreased physical properties of rubber and blooming after vulcanization. | 2012-05-31 |
20120136103 | THERMOPLASTIC POLYMER COMPOSITION CONTAINING POLYAMIDE - The invention relates to a thermoplastic polymer composition that contains polyamide and comprises an excellent compromise of properties, in particular mechanical properties, and a high fluidity at the molten state. The invention particularly relates to a composition containing at least a high-fluidity linear polyamide and optionally fillers such as glass fibres, and to a method for making such a composition. | 2012-05-31 |
20120136104 | POLYOLEFIN RESIN COMPOSITION FOR ANTI-SCRATCH IMPROVEMENT AND AUTOMOTIVE PRODUCT PREPARED FROM THE COMPOSITION - Provided is a polyolefin resin composition including: an ultra-high crystalline polypropylene resin, e.g. about 40-80 wt %, having an isotactic index of about 99.5 or higher; a branched polypropylene, e.g., about 10-20 wt %, having a branching index of about 7 or higher; a thermoplastic elastomer, e.g., about 1-20 wt %; an inorganic filler, e.g., about 1-30 wt %; and a fluoroacrylic copolymer-based amide polymer compound, e.g., about 2-6 wt %. | 2012-05-31 |
20120136105 | WATER-BORNE PRIMER - A water-borne stain blocking primer comprises a) from about 10 to about 30 wt % of a water-dispersible, hydrophobic alkyd resin having an acid number of less, than 40 KOH/g, b) from about 5 to about 30 wt % of a pigment, the pigment having an average aspect ratio of at least 3:3:1; c) from about 0.05 to about 3 wt % of a tannin chelation agent; d) from about 0 to about 20 wt % of a water-dispersible, hydrophobic free-radically polymerized copolymer; e) a hydrophobically modified associative rheology modifier in an amount effective to provide a water-borne primer having an ICI viscosity of from about 0.5 to about 3.0 poise; and a KU viscosity range of from about 80 to about 120 Krebs units; and f) water. The water-borne primer has a VOC content of less than 5%. Methods of preparing and using such water-borne stain blocking primers also are described. | 2012-05-31 |
20120136106 | Process for the Production of Polyolefins with Broad Molecular Weight Distribution - The present invention is directed to a propylene homo- or copolymer having
| 2012-05-31 |
20120136107 | Rubber-Plastic Alloy For Warm Mix Asphalt Mixture and Method for Manufacturing The Same - The present invention disclosed a rubber-plastic alloy for a warm mix asphalt mixture and a method for manufacturing the same. The warm mix rubber-plastic alloy is consisted of 5%-30% plastic, 70%-95% crumb rubber, and cracked wax and rubber oil, the summed amount of which comprises 10%-50% of the summed amount of the plastic and the crumb rubber. The manufacturing method comprises extruding the plastic, the crumb rubber, the cracked wax, and the rubber oil at suitable ratio via a single screw extruder, and pelleting via a water-cooled die-face cutter. The use comprises mixing the rubber-plastic alloy with a hot mineral material in an asphalt mixture mixer, and then liquid asphalt matrix is pumped into the mixer via an asphalt pump to provide a warm mix rubber-plastic modified asphalt mixture having excellent performance. The warm mix rubber-plastic alloy is applied for modifying an asphalt mixture to an effect equivalent to that can be achieved by a wet method, and has the advantages of simple production process, low energy consumption, continuous production, direct use, and free of the defects of high energy consumption and smoke pollution existing in a wet rubber asphalt method. | 2012-05-31 |
20120136108 | ONE-COMPONENT ORGANOPOLYSILOXANE COMPOSITIONS WITH HIGH RELATIVE PERMITTIVITY - Organopolysiloxane composition (O) curable to vulcanizates having relative permittivity ε | 2012-05-31 |
20120136109 | Composite Polymer Emulsion - A polymerization process to copolymerize hydrophobic ethylenically unsaturated C | 2012-05-31 |
20120136110 | PREPARATION OF RUBBER CONTAINING SILICA AND CARBON BLACK REINFORCEMENT, RUBBER COMPOSITION AND TIRE WITH COMPONENT - The invention relates to preparation of a rubber composition containing silica and carbon black reinforcement, the resultant rubber composition and tire with component comprised of such rubber composition. | 2012-05-31 |
20120136111 | RADIATION-CURABLE, WATER-DISPERSIBLE POLYURETHANES AND POLYURETHANE DISPERSIONS - The present invention relates to dispersible polyurethanes and polyurethane dispersions curable with UV radiation, to a process for preparing them, and to their use. | 2012-05-31 |
20120136112 | RUBBER GRANULATE CONVERSION PROCESS FOR PRODUCING A SEMI-ACTIVE CARBONIZED SUBSTANCE AND A PLASTICIZER - The present invention relates to a rubber granulate conversion process comprising steps consisting in: a) pyrolysing the rubber granulates at a temperature between 400 and 500° C. in the presence of water, to obtain a carbonized substance and a gaseous phase; and b) recovering the carbonized substance obtained during the previous step. The invention also relates to the products resulting from the conversion process and to the use of said products. | 2012-05-31 |
20120136113 | HYDROXYARYL FUNCTIONALIZED POLYMERS - A functionalized polymer includes the reaction product of a reactive polymer and a compound that includes an aryl group having at least one directly bonded OG | 2012-05-31 |
20120136114 | PROCESS FOR PRODUCING HYDROGENATED BLOCK COPOLYMER, HYDROGENATED BLOCK COPOLYMER OBTAINED BY THE PROCESS, AND COMPOSITION THEREOF - The present invention relates to a method for producing a hydrogenated block copolymer, including the steps of: (a) forming a block copolymer by allowing a living polymer having a specific structure to react with a tetra- or more functional silane coupling agent; (b) hydrogenating the block copolymer to form a hydrogenated block copolymer; (c) isolating the resultant hydrogenated block copolymer; and (d) deactivating a functional group in the silane coupling agent and/or an unreacted functional group present in a coupling agent residue in the block copolymer or the hydrogenated block copolymer prior to the step (c), in which the number of functional groups derived from the coupling agent in the hydrogenated block copolymer recovered in the step (c) is 1.5 or less per block copolymer molecule; a hydrogenated block copolymer obtained by the method; and a composition containing the hydrogenated block copolymer. | 2012-05-31 |
20120136115 | ISOCYANATE GROUP-CONTAINING PREPOLYMERS HAVING GOOD STORAGE STABILITY - The invention relates to adhesives, coating agents and sealing agents curing under the influence of moisture, which exhibit good storage stability, can be processed within a wide tolerance range and are fast-curing. | 2012-05-31 |
20120136116 | RESINS, LOW TEMPERATURE FORMULATIONS, AND COATINGS DERIVED THEREFROM - A series of resins were synthesized using a range of bio-based materials to control the molecular architecture, and therefore the properties, of the inventive resins. The utility of these resins was demonstrated in the formulation of powder coatings, such as β-hydroxy amide crosslinked and hybrid types. Generally, the bio-based resins flowed out on heating faster than conventional petrochemically-based resins, allowing the use of lower temperatures in the curing oven than is typically possible and a more active catalyst system, especially in the carboxylic acid-epoxy crosslinked hybrid coating formulations. | 2012-05-31 |
20120136117 | UNSATURATED POLYESTER - The present invention relates to a resin composition comprising (a) an unsaturated polyester resin having a molecular weight M | 2012-05-31 |
20120136118 | Styrenated phenol ethoxylates in emulsion polymerization - The present invention relates to the use of Styrenated Phenol Ethoxylates as surfactants in emulsion polymerization. The present invention further relates to the use of both anionic and nonionic Styrenated Phenol Ethoxylates in emulsion polymerization. Latexes with small average particle and narrow particle size distributions are obtained. Prepared latexes also have low coagulum levels and exhibit excellent mechanical and chemical stability. | 2012-05-31 |
20120136119 | Styrenated phenol ethoxylates in emulsion polymerization - The present invention relates to the use of Styrenated Phenol Ethoxylates as surfactants in emulsion polymerization. The present invention further relates to the use of both anionic and nonionic Styrenated Phenol Ethoxylates in emulsion polymerization. Latexes with small average particle and narrow particle size distributions are obtained. Prepared latexes also have low coagulum levels and exhibit excellent mechanical and chemical stability. | 2012-05-31 |
20120136120 | FLUORINATED SUPRAMOLECULAR POLYMERS - Fluorinated supramolecular polymers containing at least 5% by weight of covalently bonded fluorine atoms, based on total weight of the polymers are disclosed. The polymers comprise a fluorinated polymer chain and a (self-)complementary unit capable of forming at least three hydrogen bonds being covalently bonded to the fluorinated polymer chain. Also disclosed are materials comprising (a) a fluorinated supramolecular polymer and (b) a non-fluorinated polymer and/or (c) a fluorinated compound, the non-fluorinated polymer being a polymer containing less than 5% by weight of covalently bonded fluorine atoms, based on the total weight of the non-fluorinated polymer, and the fluorinated compound being either a low molecular weight fluorinated compound comprising at least one fluorine atom and having a molecular weight of 34 to 600 amu, or a fluoropolymer containing at least 5% by weight of covalently bonded fluorine atoms and a M | 2012-05-31 |
20120136121 | Polyolefin Compositions - Polyolefin compositions particularly suitable for cast film, exhibiting heat sealability, retortability, low haze and stiffness, comprising:
| 2012-05-31 |