22nd week of 2013 patent applcation highlights part 40 |
Patent application number | Title | Published |
20130137021 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS - An electrophotographic photosensitive member has a surface layer that contains a polymer produced by the polymerization of a charge transporting substance having two or more methacryloyloxy groups per molecule. The surface layer contains a quinone derivative at a concentration of 5 ppm or more and 1500 ppm or less of the total mass of the polymer. The quinone derivative is a compound represented by the following formula (1) or a compound represented by the following formula (2) or both. | 2013-05-30 |
20130137022 | IMAGE BEARING MEMBER AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE SAME - An image bearing member includes a substrate, a photosensitive layer overlying the substrate, and a surface protective layer overlying the photosensitive layer and having a surface comprising multiple concave structures with a maximum diameter of from 1 μm to 3 μm and a maximum depth of from 10 nm to 50 nm. Any one of the concave structures has at least one other concave structure within 3 μm thereof. | 2013-05-30 |
20130137023 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS - In order to provide an electrophotographic photosensitive member with which a ghost is suppressed even under a low temperature and low humidity environment, and a process cartridge and an electrophotographic apparatus having the electrophotographic photosensitive member, the electrophotographic photosensitive member has a support, an undercoat layer formed on the support, and a photosensitive layer formed on the undercoat layer and comprising a charge generating material and a hole transporting material, wherein the undercoat layer comprises a particular amine compound. | 2013-05-30 |
20130137024 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS - In an electrophotographic photosensitive member having a surface layer containing a polymer obtainable by polymerization of a compound having a chain-polymerizable functional group, the compound having a chain-polymerizable functional group includes a compound represented by formula (1). | 2013-05-30 |
20130137025 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD OF PRODUCING PHTHALOCYANINE CRYSTAL, METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND PHTHALOCYANINE CRYSTAL - Provided is an electrophotographic photosensitive member including a support and a photosensitive layer formed on the support, in which the photosensitive layer includes a phthalocyanine crystal containing a compound satisfying the following formulae (A) and (B) in itself: 8.9≦δP≦10.7 (A) and −3.2≦L≦−1.5 (B) (in the formula (A), δP represents a polar term of Hansen Solubility Parameters, and in the formula (B), L represents an energy level (eV) of an LUMO (lowest unoccupied molecular orbital) obtained as a result of structural optimization calculation based on density functional calculation B3LYP/6-31G). | 2013-05-30 |
20130137026 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS - An electrophotographic photosensitive member includes a support, a charge-generating layer disposed on the support, and a charge-transporting layer disposed on the charge-generating layer, in which the charge-generating layer contains a charge-generating substance and a compound represented by the formula (1). A process cartridge includes the electrophotographic photosensitive member described above. An electrophotographic apparatus includes the electrophotographic photosensitive member described above. | 2013-05-30 |
20130137027 | CHARGE TRANSPORT LAYER FOR ORGANIC PHOTOCONDUCTORS - An organic photoconductor includes an inner charge generation layer for generating charges and an outer charge transport layer for facilitating charge transport. The charge transport layer comprises a semi-interpenetrating hole-transport polymer or oligomer network in which the polymer or oligomer is cross-linked. A process for forming a charge transport layer in an organic photoconductor is also provided. | 2013-05-30 |
20130137028 | METHOD OF MANUFACTURING TONER CARRIER, DEVICE FOR MANUFACTURING TONER CARRIER, TONER CARRIER, DEVELOPMENT AGENT, AND PROCESS CARTRIDGE - A method of manufacturing toner carrier formed of a core and a cover thereon, including the steps of: coating the core with a liquid cover containing a solvent and a material for forming the cover on the core in a processing tank; heating the core and the cover by first microwave radiation to volatilize the solvent from the cover; and removing the solvent volatilized in the step of heating from the processing tank. | 2013-05-30 |
20130137029 | TONER FOR ELECTROSTATIC IMAGE DEVELOPMENT AND IMAGE FORMING METHOD - Disclosed are a toner for electrostatic image development which is able to realize enough charge stability over a long period of time as deterioration of a toner due to mechanical stress is prevented in a developing unit, and to prevent generation of filming, and an image forming method using the same. | 2013-05-30 |
20130137030 | TONER, DEVELOPER, TONER CARTRIDGE, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS, AND IMAGE FORMING METHOD - An electrostatic charge image developing toner includes toner particles containing a binder resin and pigment particles and an external additive containing fluorine resin particles, wherein the electrostatic charge image developing toner satisfies the following expression: 2≦A/B≦100, wherein A represents reflectance at an acceptance angle of +30° which is measured when a solid image is formed using the electrostatic charge image developing toner and the solid image is irradiated with incident light at an incidence angle of −45° by the use of a variable-angle photometer, and B represents reflectance at an acceptance angle of −30° which is measured when the solid image is irradiated with incident light at an incidence angle of −45° by the use of the variable-angle photometer. | 2013-05-30 |
20130137031 | ELECTROPHOTOGRAPHIC TONER AND METHOD FOR PRODUCING THE SAME - An electrophotographic toner produced by mixing a dispersion of colorant particles containing a colorant and a dispersion of release agent particles containing a release agent and having a volume average particle diameter smaller than that of the colorant particles, aggregating the colorant particles and the release agent particles in the dispersion to produce first aggregates, mixing a dispersion of resin particles containing a binder resin and having a volume average particle diameter smaller than that of the release agent particles in the dispersion containing the first aggregates, and aggregating the first aggregates and the resin particles in the dispersion of the first aggregates and the resin particles to coat the first aggregates with the resin particles, producing second aggregates. | 2013-05-30 |
20130137032 | METHOD OF PRODUCING GALLIUM PHTHALOCYANINE CRYSTAL AND METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER USING THE METHOD OF PRODUCING GALLIUM PHTHALOCYANINE CRYSTAL - Provided is a method of producing an electrophotographic photosensitive member having improved sensitivity and capable of outputting an image having less image defects due to a ghost phenomenon not only under a normal-temperature, normal-humidity environment but also under a low-temperature, low-humidity environment as a particularly severe condition. The method of producing a gallium phthalocyanine crystal includes subjecting a gallium phthalocyanine and a specific amine compound, which are added to a solvent, to a milling treatment to perform crystal transformation of the gallium phthalocyanine. In addition, the gallium phthalocyanine crystal is used in the photosensitive layer of the electrophotographic photosensitive member. | 2013-05-30 |
20130137033 | PROCESS FOR PREPARING STRUCTURED ORGANIC FILMS (SOFS) VIA A PRE-SOF - A processes for preparing structured organic film (SOF) comprising a plurality of segments and a plurality of linkers arranged as a covalent organic framework, wherein the structured organic film may be a multi-segment thick structured organic film. | 2013-05-30 |
20130137034 | METHOD OF PRE-TREATING A WAFER SURFACE BEFORE APPLYING A SOLVENT-CONTAINING MATERIAL THEREON - A method for pre-treating a wafer surface before applying a material thereon. The method includes positioning the wafer on a rotating apparatus. The wafer is rotated at a first rotational speed between about 50 revolutions per minute (rpm) and about 300 rpm and for a period of about 1 second to about 10 seconds while dispensing a cleaning solvent on the wafer surface. The wafer is rotated at a second rotational speed between about 500 rpm and about 1,500 rpm for a period of about 1 second to about 10 seconds. The wafer is then rotated at a third rotational speed between about 50 rpm and about 300 rpm for a period of about 1 second to about 5 seconds. With the wafer rotating at the third rotational speed, a solvent-containing material is thereafter deposited on the surface of the wafer. | 2013-05-30 |
20130137035 | SURFACE ACTIVE ADDITIVE AND PHOTORESIST COMPOSITION COMPRISING SAME - A polymer comprises the polymerized product of monomers comprising a nitrogen-containing monomer comprising formula (Ia), formula (Ib), or a combination of formulas (Ia) and (Ib), and an acid-deprotectable monomer having the formula (II): | 2013-05-30 |
20130137036 | Positive Photosensitive Resin Composition, Photosensitive Resin Film Prepared by Using the Same, and Semiconductor Device Including the Photosensitive Resin Film - Disclosed are a positive photosensitive resin composition that includes (A) a polybenzoxazole precursor including a first polybenzoxazole precursor including a repeating unit represented by the following Chemical Formula 1 and a repeating unit represented by the following Chemical Formula 2, and having a thermally polymerizable functional group at at least one of the terminal end; (B) a dissolution controlling agent including a novolac resin including a repeating unit represented by the following Chemical Formula 4; (C) a photosensitive diazoquinone compound; (D) a silane compound; (E) an acid generator; and (F) a solvent, a photosensitive resin film prepared using the same, and a semiconductor device including the photosensitive resin film. | 2013-05-30 |
20130137037 | Silicon Compound, Condensation Product, Resist Compostion and Pattern Formation Method - A silicon compound according to the present invention is represented by the general formula (1). This silicon compound can be easily synthesized by using a hydrolysable silicon compound such as alkoxysilane and has, in its molecule, a hydrolysable group e.g. alkoxy group and a photoacid generating group capable of being dissociated to generate an acid by irradiation with a high-energy ray. | 2013-05-30 |
20130137038 | PHOTORESIST COMPOSITION - A photoresist composition comprises an acid-sensitive polymer, and a cyclic sulfonium compound having the formula: | 2013-05-30 |
20130137039 | Photosensitive Resin Composition for Color Filter and Color Filter Prepared Using the Same - Disclosed are a photosensitive resin composition for a color filter that includes a colorant including a phthalocyanine-based compound represented by the following Chemical Formula 1 and a triarylmethane-based compound represented by the following Chemical Formula 2, wherein the substituents of Chemical Formulas 1 and 2 are the same as same as defined in the detailed description, and a color filter prepared using the same. | 2013-05-30 |
20130137040 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PRODUCING THEREOF - To provide an on-press development type lithographic printing plate precursor excellent in ink receptivity and printing durability. A lithographic printing plate precursor which includes a support, an image-recording layer which contains a sensitizing dye, a polymerization initiator and a polymerizable compound and an unexposed area of which is capable of being removed by supplying after exposure, at least any of printing ink and dampening water on a printing machine, and an overcoat layer containing a water-soluble resin in this order, wherein the overcoat layer is substantially not mixed with the image-recording layer. | 2013-05-30 |
20130137041 | SILICON-CONTAINING RESIST UNDERLAYER FILM-FORMING COMPOSITION AND PATTERNING PROCESS - The present invention is a silicon-containing resist underlayer film-forming composition containing at least any one of a condensation product and a hydrolysis condensation product or both of a mixture comprising: one or more kinds of a compound (A) selected from the group consisting of an organic boron compound shown by the following general formula (1) and a condensation product thereof and one or more kinds of a silicon compound (B) shown by the following general formula (2). Thereby, there can be provided a resist underlayer film applicable not only to the resist pattern formed of a hydrophilic organic compound obtained by the negative development but also to the resist pattern formed of a hydrophobic compound obtained by the conventional positive development. | 2013-05-30 |
20130137042 | PHOTOSENSITIVE COMPOSITION AND PHOTORESIST - A photosensitive composition and a photoresist are provided. The photoresist is formed by compounding a photosensitive composition. The photosensitive composition comprises a binder agent, a photomonomer and a photoinitiator. The binder agent has a chemical structure comprising following repeating unit: | 2013-05-30 |
20130137043 | PHOTOSENSITIVE ELEMENT HAVING REINFORCING PARTICLES AND METHOD FOR PREPARING A PRINTING FORM FROM THE ELEMENT - The invention provides a photosensitive element and a method for preparing a printing form from the element. The photosensitive element includes a layer of a photosensitive composition containing a binder, a monomer, and a Norrish type II photoinitiator, wherein the photosensitive layer has a transmittance to actinic radiation of less than 20% and contains reinforcing particles of graphene and/or carbon nanotubes. | 2013-05-30 |
20130137044 | SCANNING APPARATUS, DRAWING APPARATUS, AND METHOD OF MANUFACTURING ARTICLE - A scanning apparatus which performs scan on an object with a charged particle beam includes: a blanking deflector configured to individually blank a plurality of charged particle beams based on control data; a scanning deflector configured to collectively deflect the plurality of charged particle beams to perform the scan; and a controller. The controller is configured to hold first data used to obtain error in a scanning amount and a scanning direction of the scanning deflector relative to a reference scanning amount and a reference scanning direction with respect to each of the plurality of charged particle beams, and to generate the control data based on the first data so that the scan is performed for a target region on the object. | 2013-05-30 |
20130137045 | UV Glass Production Method - The present invention discloses a UV glass production method, comprising the steps: arranging a blade on an exposure stage; controlling the position of an exposure area on a glass substrate by regulating the position of the blade; removing a film layer from the area to be transparent; and forming a UV mask in the area to be shaded. In the present invention, a mask blade is adopted, can individually move and be accurately controlled individually; thus, rays of an exposure machine can be accurately positioned for producing a UV glass which meets standards. Moreover, in the present invention, there is no need to design a light cover especially so as to save the design and production cost of the light cover; thus, the present invention can ensure the production accuracy and effectively save the production cost. | 2013-05-30 |
20130137046 | PHASE DIFFERENCE LAYER LAMINATED BODY FOR THREE DIMENSIONAL LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF - A phase difference layer laminated body used in a three-dimensional liquid crystal display device, wherein unit cells are divided into groups for left and right eyes, which are given different degrees of polarization, thereby creating a three-dimensional image, further wherein the phase difference layer laminated body has a base material having orientability, and a phase difference layer made of a liquid crystal material that can form a nematic phase and formed in a pattern with two different portions, and the liquid crystal material in each of two different portions is oriented to have different refractive index anisotropy each other that conforms to the two different degrees of polarization and fixed as it is. | 2013-05-30 |
20130137047 | METHOD OF FORMING RESIST PATTERN - A method of forming a resist pattern including: step (1) in which a resist composition including a base component and a photobase generator component is applied to a substrate to form a resist film; step (2) in which the resist film is subjected to immersion exposure; step (3) in which baking is conducted after step (2), such that, at an exposed portion of the resist film, the base generated from the photobase generator component and an acid provided to the resist film in advance are neutralized, and at an unexposed portion of the resist film, the solubility of the base component in an alkali developing solution is increased by the action of the acid; and step (4) in which the resist film is subjected to an alkali development, thereby forming a negative-tone resist pattern, wherein a receding angle of water on the resist film is 65° or more. | 2013-05-30 |
20130137048 | RESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN - A resist composition containing a base component (A) which generates an acid upon exposure and exhibits changed solubility in a developing solution by the action of acid, wherein the base component (A) contains a copolymer (A1) having a structural unit (a0) containing a group represented by the following general formula (a0-1) or (a0-2), a structural unit (a11) containing an acid-decomposable group which exhibits increased polarity by the action of acid and contains a polycyclic group, and a structural unit (a12) containing an acid-decomposable group which exhibits increased polarity by the action of acid and contains a monocyclic group. Each of the groups —R | 2013-05-30 |
20130137049 | METHOD OF FORMING POLYMERIC COMPOUND, RESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN - A method of producing a polymeric compound, including: copolymerizing a monomer containing an —SO | 2013-05-30 |
20130137050 | METHOD OF CALCULATING AMOUNT OF FLUCTUATION OF IMAGING CHARACTERISTIC OF PROJECTION OPTICAL SYSTEM, EXPOSURE APPARATUS, AND METHOD OF FABRICATING DEVICE - In a case where a substrate is exposed to exposure light of a first wavelength band, an exposure coefficient, which is defined as an amount of fluctuation of an imaging characteristic of a projection optical system per unit of exposure energy, for the first wavelength band is calculated using data of the amount of fluctuation of the optical characteristic of the projection optical system. An exposure coefficient for a second wavelength band that is different from the first wavelength band is calculated using the exposure coefficient for the first wavelength band. In a case where the substrate is exposed to exposure light of the second wavelength band, the amount of fluctuation of the imaging characteristic of the projection optical system is calculated using the exposure coefficient for the second wavelength band. | 2013-05-30 |
20130137051 | BURNER AND METHOD FOR PARTIALLY OXIDIZING LIQUID, CARBON-CONTAINING FUEL - A burner for the partial oxidation of liquid, carbonaceous fuel with steam and an oxygen-containing gas a well as the process in which this burner is used, wherein the parts of the outlet orifice of the burner directed towards the combustion chamber are wholly or partly provided with a coating or with a diffusion layer for protection against thermal load and/or corrosion. | 2013-05-30 |
20130137052 | NON-CATALYTIC BIOMASS FUEL BURNER AND METHOD - The present invention relates to a non-catalytic biomass burner that may be used to burn a variety of fuel types at high efficiencies. The burner may include a cylindrical combustion chamber with an auxiliary igniter to heat the fuel in the combustion chamber until desirable combustion temperatures are reached. Fuel may be added to the chamber via a fuel feed assembly, and the rate of fuel addition to the chamber by the fuel feed assembly may be controlled by a computer. A fan located on the distal side of a flue pipe from the chamber may also be provided that pulls air into the chamber through one or more air inlets that are designed to encourage cyclonic air and exhaust flow in the chamber. Methods are further provided for controlling the manner of operation of the burner by a computer that may be instructed by a computer program code. | 2013-05-30 |
20130137053 | Apparatus and Method for Thermo-Transformation of Wood - An apparatus for thermo-transformation of wood planks comprises a chamber delimited by upright perforated walls, a top wall and end walls and having a closable entry for receiving wood planks into the chamber. A shell surrounds the chamber and is spaced therefrom to define a first vertical plenum with the first perforated wall, a second vertical plenum with the second perforated wall, and a horizontal plenum with the top wall. A ventilation system is in fluid communication with the plenums to produce a flow of heated air in the plenums. Vanes are actuatable to close/open access to the vertical plenums, to allow heated air into at least one of the vertical plenums, through the chamber via the perforated walls, and out from at least the other of the vertical plenums, to return to the ventilation system. A method for the thermo-transformation of wood is also provided. | 2013-05-30 |
20130137054 | INFRARED LIGHT- AND THERMAL-RESPONSIVE GRAPHENE OXIDE HYDROGEL POLYMER COMPOSITES - Composite hydrogels and methods for making and using the composite hydrogels are provided. The composite hydrogels comprise graphene oxide flakes distributed in, and covalently bonded to, a thermo-responsive hydrogel polymer. | 2013-05-30 |
20130137055 | Combustion Device for Melting Furnace and Melting Furnace - A combustion device for a melting furnace, capable of heating a melting target object and the ceiling portion of the furnace with the radiant heat of the flame, including a combustion space above the location of the melting target object, including a fuel injection nozzle having a plurality of fuel injecting portions, which portions include orifices disposed side by side horizontally relative to the direction of fuel injection, and formed side by side vertically relative to the same. The orifices are formed radially side by side as seen laterally, with a direction along a middle angle in the angular range between the fuel injection direction of the uppermost fuel injection orifice and the fuel injection direction of the lowermost fuel injection orifice being directed obliquely upwards. The fuel injection orifices of the upper fuel injecting portion are formed radially side by side as seen in the plane view. | 2013-05-30 |
20130137056 | HEAT CHAMBER - A heat chamber having multiple segments formed from castable material. | 2013-05-30 |
20130137057 | CARRIER FOR DENTAL IMPRESSION COMPOUND - The invention relates to a carrier for a dental impression material for insertion into an impression tray or attachment to a holding device, having a base area which replicates the human jaw and is delimited on two opposing sides by walls in order to form an approximately U-shaped cross section, wherein at least one optical element is arranged in the base area and/or the walls. | 2013-05-30 |
20130137058 | Dental Tools for Photo-Curing of Dental Fillings - A dental tool for use in photo-cured filling processes. The dental tool includes a tool tip formed from a material that allows the transmission of ultraviolet and visible light wavelengths through the tool tip without significant distortion or reflection. The material is also relatively high strength so not to shatter or break during use. The fill material will also not easily adhere to the tool. The material of a preferred embodiment is sapphire. The tool is able to continue to compact and shape the fill material while the composite polymer fill material is undergoing photo-curing. The light beam used for photo-curing is able to safely pass through the tool without the risk of damage to the surrounding tissue from reflection or distortion of the light beam. | 2013-05-30 |
20130137059 | SYSTEM FOR ABLATING MATERIAL IN THE ORAL CAVITY - The invention relates to a method for ablating solid material in the oral cavity, particularly jaw bone material. Known systems are disadvantageous in terms of precision and causing damage to the surrounding tissue. The object of the invention is to provide a system that allows for easy, safe, gentle, reliable and precise ablation. The object is achieved by the use of a fixation device, particularly a dental splint, and an insertion device that can be rigidly connected thereto and is particularly designed to introduce laser radiation and thereby ablate material, and that is in a fixed, predetermined position after having been connected. | 2013-05-30 |
20130137060 | Dental Handpiece - A dental handpiece having a reciprocal rotation means for converting a rotary motion to a reciprocating rotating motion is disclosed. The reciprocal rotation means includes a rotary body having input- and output-side guide grooves, input- and output-side semispherical concave surface formed at the ends of input- and output-side shaft part, respectively, of a rotary shaft extending in a grip of the handpiece, and input- and output-side guide pin protruding from the input- and output-side semispherical concave surface, respectively for engagement in the input- and output-side guide grooves, respectively. | 2013-05-30 |
20130137061 | DENTAL IMPLANTS, DEVICES AND METHODS ASSOCIATED WITH DENTAL IMPLANTATION PROCEDURES - A dental implant installation procedure is provided in which a distal end of a dental implant is projected into a paranasal sinus cavity or a nasal cavity to thereby displace the respective sinus membrane or nasal cavity membrane from the respective cavity floor, while minimizing risk of damaging the respective membrane. Bone graft material is introduced into the space thereby created between the respective membrane and the respective cavity floor via a distal portion of the dental implant to thereby form a desired sinus augmentation. | 2013-05-30 |
20130137062 | METHOD FOR TAKING A DENATL IMPRESSION - A method for making a cast of a tooth using a curable dental impression compound containing a ferromagnetic compound, preferably an iron powder additive as well as a method for guiding the compound into the sub-gingival areas of the tooth by the use of a magnetic field. The term “ferromagnetic” as used herein is used to describe a substance that is capable of being attracted by a magnetic field, in particular a substance that exhibits a high degree of magnetic permeability. | 2013-05-30 |
20130137063 | Delivery of Oral Care Products - A method for the delivery of an oral care active agent comprising the following step: applying an active agent(s) between a target oral biological barrier and a magnetic device comprising one or more pairs of displaced dipolar magnetic elements linked by a magnetic return wherein the magnetic return is orientated on the surfaces of the dipole pair distal to the biological barrier. | 2013-05-30 |
20130137064 | COATED DENTAL CROWNS AND METHOD OF MAKING THE SAME - Provided are methods of improving the wear resistance and aesthetic properties of dental articles, as well as dental articles having an abrasion resistant ceramic/polymer hybrid coating thereon. | 2013-05-30 |
20130137065 | Dental Articles Including a Ceramic and Microparticle Coating and Method of Making The Same - Provided are methods of improving the wear resistance and aesthetic properties of dental articles though use of ceramics and microparticles, as well as dental articles having an abrasion resistant microparticle and ceramic coating thereon. | 2013-05-30 |
20130137066 | PHYSICS-BASED SIMULATION OF WARHEAD AND DIRECTED ENERGY WEAPONS - A network connects stations in a distributed physics based simulation system. When the simulation detects that a weapon, especially a missile or directed energy beam, is engaging a target vehicle, one physics station determines damage status of the target vehicle. The detonation or strike of the weapon is applied to a model of the vehicle composed of pieces each made up of a number of parts. Where the damage to a piece of the vehicle exceeds a predetermined threshold, the piece is removed from the vehicle, and where a predetermined maximum damage is reached for the vehicle, the vehicle is considered destroyed. The damage assessment from the weapon is made using raytracing in a physics engine that is also used to control movement of virtual objects in the simulation according to rules of physics of the physics engine. | 2013-05-30 |
20130137067 | METHOD OF EXPRESSION - A method of expression includes exhibiting a sculpture which embodies a living organism. The sculpture has several different components which are representative of parts and processes which are need to support the life and growth of a living organism. | 2013-05-30 |
20130137068 | METHOD OF TRANSFORMING A HUMAN BODY THROUGH ENERGY SOURCE CYCLING - The present invention diet, system, device, and method of transforming a body through energy source cycling that does not require a person to go without food to accomplish the same fat burning results. The invention requires a person to restrict carbohydrates for two to three days and then eat a normal amount of carbohydrates for one to two days. This cycle is then repeated. | 2013-05-30 |
20130137069 | CARD GAME - A card and deck of cards for teaching information to a user each comprising a substantially planar body having first and second sides. A question portion is provided on the first side and an answer portion is provided on the second side. At least one value region having an indication representing a standard playing card value is also provided on the second side. | 2013-05-30 |
20130137070 | APPARATUS AND METHOD OF MANIPULATING NUMERIC PANELS - An apparatus and method of manipulating numeric panels according to an evaluation of a division operation using a division token is provided. At step (1) of the method, a method participant uses a mathematical operator token to randomly select a mathematical operator from a plurality of mathematical operators one of which being a division operator. At step (2) of the method, upon the selected mathematical operator comprising the division operator, the method participant randomly selects a division operation from a plurality of predefined division operations using a division token and evaluating the selected division operation, the division token comprising a plurality of division indicia each associated with one of the predefined division operations, each of the division operations evaluating solely to an integer quotient. At step (3) of the method, the method participant manipulates a subset of available panels from an array of numeric panels. | 2013-05-30 |
20130137071 | Washburn Orthopedic Module (WOM) - I. The Washburn Ortho-Module (WOM) is a devise that is useful for orthopedic surgeons to learn and refine their tactile sense of placement of orthopedic hardware into bone that has different densities based on calculated patient age, medical history and radiological imaging (I.E., Dual-energy x-ray absorptiometry [dexa-scan], etc). | 2013-05-30 |
20130137072 | TEST AND METHOD FOR DETECTION OF EXCESSIVE FATIGABILITY AS INDICATOR OF SUBCLINICAL DEPRESSION OR PREDICTOR OF UPCOMING DEPRESSION - A test or system for detection of increased/excessive fatigability and as a screening tool for on- or up-coming depression, and Chronic Fatigue Syndrome. Fatigue is dissected into components including general feelings, activity, and emotions, each expressed through sets or pairs of opposite feelings. Between the opposite feelings there is a scale, from which the person will select the most applicable point that best reflects the person's present feelings. The scale is scored, and based on the score it is determined whether to perform the test again, or to evaluate for depression. If the test is performed again, need for further evaluation is determined from that score. | 2013-05-30 |
20130137073 | SOFTWARE AND METHOD FOR INDOOR CYCLING INSTRUCTION - An application software that combines instructional cues with music along with a graphic representation of a workout, such as a cycling workout, for teaching one or more individuals riding stationary bikes, or regular bicycles on stationary trainers, performing other exercises, used for indoor exercise or training. Instructors of indoor cycling or Spinning® classes can use their mobile device to create a class that contains music for the class, their instructional cues by voice or text, and an automatically generated graphic profile of the ride of workout. The climb or graph is represented by harder exercise efforts appearing higher on the graph, with easier efforts appearing lower as a function of the target heart zone or percent of max heart rate. Colors can be associated with specific cardiovascular or power zones of physical difficulty or intensity. By having the music, instructional cues, and graphics related to the class all in the same mobile device, the instructor no longer has to try and work with multiple items or devices while riding a stationary bike. | 2013-05-30 |
20130137074 | TOOTHBRUSH MONITORING DEVICE - The invention relates to a toothbrushing monitoring device ( | 2013-05-30 |
20130137075 | PROSTATE BRACHYTHERAPY SIMULATOR - Methods for forming a prostate brachytherapy simulator are provided. A method comprises forming a molded rectum model between tubes secured to a base component of a container. The base component has a first open-bottomed cup that opens to an exterior of the container and a second cup that contains the first open-bottomed cup. The method also comprises forming a molded prostate model from recyclable materials. Additionally, the method comprises placing the prostate model relative to the rectum model. The method also comprises providing a gel-based environment that surrounds the rectum model and the prostate model within a container. | 2013-05-30 |
20130137076 | HEAD-MOUNTED DISPLAY BASED EDUCATION AND INSTRUCTION - Technology disclosed herein provides for use of HMDs in a classroom setting. Technology disclosed herein provides for HMD use for holographic instruction. In one embodiment, the HMD is used for social coaching. User profile information may be used to tailor instruction to a specific user based on known skills, learning styles, and/or characteristics. One or more individuals may be monitored based on sensor data. The sensor data may come from an HMD. The monitoring may be analyzed to determine how to enhance an experience. The experience may be enhanced by presenting an image in at least one head mounted display worn by the one or more individuals. | 2013-05-30 |
20130137077 | SYSTEM AND METHOD FOR CONDUCTING HIGH STAKE EXAMINATIONS USING INTEGRATED TECHNOLOGY PLATFORM - The present invention relates to a system and method, which enables to conduct and management of high stake examinations online in a distributed mode. More specifically, the present invention provides an integrated technology platform for conducting both online and offline examinations in a secured manner. The technology platform provides end-to-end solutions, which covers online application, online hall ticket generation, online question bank authoring, secured question paper generation and online delivery, digital evaluation of hand written answer scripts, result processing and online publishing of the result and digital generation of mark sheets and degree certificates with a unique global access code (GAC) per certificate. | 2013-05-30 |
20130137078 | EDUCATIONAL-SOCIAL NETWORK - Systems and methods for collecting information about a student's educational and social activities from a plurality of networked sources, storing the information, and providing access to the information are provided. A collection component receives information associated with a student, including at least educational activity information. A portfolio component then associates the information in a portfolio for the student, which is stored in a data store, and an access component provide access to the portfolio. An educational activity component provides educational activities to the student and a social activity component provides a public interface and social activities for students. | 2013-05-30 |
20130137079 | REFERENCE BASED POSITIONING OF HANDHELD TOOLS - A method for positioning a handheld tool is disclosed. In one embodiment, information is received at a handheld tool for positioning a working end of the handheld tool at a desired position. Information is also received at the handheld tool for aligning the handheld tools at the desired position. | 2013-05-30 |
20130137080 | Micromanipulation and Storage Apparatus and Methods - An apparatus for micromanipulation of biological material, includes a vessel ( | 2013-05-30 |
20130137082 | BIOSENSOR, APPARATUS AND METHOD FOR DETECTING A BIOMOLECULE USING THE BIOSENSOR - Provided are a biosensor, an apparatus and a method for detecting a biomolecule using the biosensor. The biosensor may include a supporting substrate, a semiconductor layer spaced apart from a top surface of the supporting substrate by supporting patterns, and a nano-motor array formed on a top surface of the semiconductor layer. The nano-motor array may include a plurality of nano-metal rods configured to exhibit an autonomous propulsion in a fluid. | 2013-05-30 |
20130137083 | Detection of H5N1 Influenza Infection - A combination of H5N1 influenza peptides that provide for H5N1 diagnosis with a high level of sensitivity and specificity is described. | 2013-05-30 |
20130137084 | Single Nucleotide Polymorphism on Chromosome 15 That Predicts HCV Treatment Responses - The present invention is based on the discovery of associations that exist between single nucleotide polymorphisms (SNPs) on chromosome 15 and virological outcomes in a diverse population of patients with hepatitis C virus (HCV) who received interferon-based treatment. | 2013-05-30 |
20130137085 | Method for Real-Time Measurement of the Individual Secretions of a Cell - The present invention relates to a method for real-time measurement of the secretion of at least one compound by at least one individual cell, comprising:
| 2013-05-30 |
20130137086 | HPV DNA Methylation Patterns of Diagnostic or Prognostic Significance in Cervical Cancer Screening - Disclosed are methods, compositions, devices, and systems for assessing cancer potential, state, stage, risk of progression, prognosis, etc. of a subject based on determining the methylation state of human papillomavirus (HPV) in a sample from the subject. The cancers assessed generally can be cancer associated with or caused by HPV. For example, cervical cancer, vulvar cancer, penile cancer, anal cancer, and head and neck cancer can be associated with HPV. It has been discovered that certain patterns, profiles, and sets of methylation of HPV genomes are correlated with different cancer potential, state, stage, risk of progression, prognosis, etc. | 2013-05-30 |
20130137087 | SYSTEM AND METHOD INCLUDING ANALYTICAL UNITS - Systems and methods for processing and analyzing samples are disclosed. The system may process samples, such as biological fluids, using assay cartridges which can be processed at different processing locations. In some cases, the system can be used for PCR processing. The different processing locations may include a preparation location where samples can be prepared and an analysis location where samples can be analyzed. To assist with the preparation of samples, the system may also include a number of processing stations which may include processing lanes. During the analysis of samples, in some cases, thermal cycler modules and an appropriate optical detection system can be used to detect the presence or absence of certain nucleic acid sequences in the samples. The system can be used to accurately and rapidly process samples. | 2013-05-30 |
20130137088 | FACTOR INVOLVED IN LATENT INFECTION WITH HERPESVIRUS, AND USE THEREOF - Disclosed are a protein and a gene each of which is a factor involved in latent infection with a herpesvirus. An antibody against the factor was detected in approximately 50% of patients suffering from mental disorders, whereas the antibody was hardly detected in healthy persons. Further, a mouse having SITH-1 introduced therein developed a mental disorder such as a manic-depressive illness or depression-like disorder. Based on these findings, it is possible to provide a method for objectively determining a mental disorder and an animal model of a mental disorder. | 2013-05-30 |
20130137089 | HUMAN GASTROINTESTINAL STEM CELL-DERIVED PRIMARY INTESTINAL EPITHELIAL CELL SYSTEM AND METHODS OF USE THEREOF - The present invention relates to an intestinal primary epithelial cell system for detecting gastrointestinal segment-specific activation or suppression of a Toll-like receptor (TLR) by a target agent. The cell system includes an isolated human intestinal primary epithelial cell (HIPEC) line that expresses at least one TLR, where the HIPEC line is derived from a differentiable adult human gastrointestinal stem cell (ahGISC) line. Also disclosed are various methods of using the cell system, a kit that includes the cell system, and an isolated cell culture including an isolated HIPEC line derived from a differentiable ahGISC line. | 2013-05-30 |
20130137090 | NUCLEIC ACID APTAMER-BASED DIAGNOSTIC METHODS WITH NOVEL TECHNIQUES FOR SIGNAL ENHANCEMENT - The present invention concerns methods for the detection of target molecules in a sample including several steps of signal amplification allowing the detection of a very low number of target molecules in the tested sample. The detection assay is based on the use of a universal probe which enables the signal amplification. The specific recognition of the target molecule is achieved by using a specific binding agent, preferably an aptamer. The invention further concerns kits and methods for the diagnosis of pathological conditions. | 2013-05-30 |
20130137091 | Methods And Compositions For Incorporating Nucleotides - The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. The methods of the invention include correcting one or more phenomena that are encountered during nucleotide sequencing, such as using sequencing by synthesis methods. These phenomena include, without limitation, sequence lead, sequence lag, spectral crosstalk, and noise resulting from variations in illumination and/or filter responses. | 2013-05-30 |
20130137092 | DEVICE FOR DETECTING AND SEPARATING TARGET MOLECULES AND METHOD FOR DETECTING AND SEPARATING TARGET MOLECULES BY USING THE SAME - A device, system, and method for detecting or separating target molecules allowing efficient detection even when only a small amount of target molecules or target cells are included in a sample involving the use of a target molecule linkage portion, a signal production portion, and first and second separation portions. | 2013-05-30 |
20130137093 | SYSTEMS AND METHODS FOR MANAGING INVENTORIES OF REAGENTS - A system for managing the inventory of reagents for a laboratory automation system. The system for managing the inventory of reagents comprises a controller, software for the controller, and a refrigerator capable of refrigerating reagents, detecting the presence or absence of reagents in the refrigerator, and detecting the location of reagents in the refrigerator. The system for managing the inventory of reagents is connected to a laboratory automation system. The laboratory automation system comprises at least one clinical analyzer. A typical system for managing inventories of reagents includes an operator interface for the loading of boxes of reagents and other supplies, radio frequency identification system for identification of inventory and tracking, robotic mechanisms for loading containers onto the track system and removing containers from the track system, de-capping equipment, refrigeration equipment, and information technology connections to laboratory analyzers and vendors. | 2013-05-30 |
20130137094 | One-Step Cell and Tissue Preservative for Morphologic and Molecular Analysis - The invention relates to a one-step chemical composition that preserves animal tissue, cells, and biomolecules, such as human tissue, human cells, and biomolecules therein. It improves the fidelity and morphologic structure of cells, organelles, and nuclear chromatin, and maintains and enhances the cellular antigenicity for immunohistochemistry and flow cytometry, while preserving proteins, post-translational modifications of proteins, and nucleic acids. In one embodiment, the composition comprises a) a non-aldehyde precipitating fixative at a concentration below 25% (volume/volume), b) a reversible/cleavable protein cross-linker that targets lipid-associated molecules, and c) a c reversible/cleavable protein cross-linker that targets water soluble molecules. In another embodiment, the composition further includes a kinase inhibitor, a phosphatase inhibitor, and a permeation enhancer. In still another embodiment, the compositions further include lactic acid at a concentration sufficient to maintain cellular nuclear volume at a level equivalent to aldehyde fixation of the same type of cell. In a further embodiment, the composition comprises: a) a precipitating fixative, b) a reversible/cleavable cross-linker, c) a permeation enhancer, d) a kinase inhibitor, e) a phosphatase inhibitor, and f) a carboxylic acid. In a still further embodiment, the invention comprises method for preserving a biological sample by contacting the sample with the composition of the invention under conditions effective for the preservation of the sample. | 2013-05-30 |
20130137095 | METHOD FOR IDENTIFYING TARGET BASE SEQUENCE - A method for identifying a base sequence accompanying competitive hybridization that includes a thermal denaturation subjecting a sample double-stranded nucleic acid and a reference double-stranded nucleic acid containing the same base sequence as a target base sequence to thermal denaturation treatment in a single reaction solution, a temperature lowering carrying out competitive hybridization between the sample double-stranded nucleic acid and the reference double-stranded nucleic acid by lowering the temperature of the reaction solution after the thermal denaturation, a measurement measuring a double-stranded nucleic acid formed by a nucleic acid strand that composed the reference double-stranded nucleic acid and a nucleic acid strand that composed the sample double-stranded nucleic acid, and an identification identifying identity between the reference double-stranded nucleic acid and the sample double-stranded nucleic acid based on measurement results obtained from the measurement, the temperature lowering being carried out in the presence of a cationic comb-type polymer. | 2013-05-30 |
20130137096 | Diagnosis of Hereditary Spastic Paraplegias (HSP) by Identification of a Mutation in the ZFVYE26 Gene or Protein - The Invention relates to an ex vivo method of diagnosing or predicting a hereditary spastic paraplegias (HSP), in a subject, which method comprises detecting a mutation in the ZFYVE26 gene or protein (spastizin), wherein said mutation is indicative of a hereditary spastic paraplegias (HSP). | 2013-05-30 |
20130137097 | HIGH THROUGHPUT SINGLE NUCLEOTIDE POLYMORPHISM ASSAY - A method consisting of a homogeneous assay detection system for a PCR process using FRET for detection and zygosity analysis of the HaAHASL1-A122(At)T single nucleotide polymorphism in sunflower is provided. The method provides specific sunflower-genome primers that can be used to detect the presence or absence of the HaAHASL1-A122(At)T single nucleotide polymorphism. The primer combinations for use in an endpoint PCR assay capable of determining zygosity and for assisting in breeding introgression are described. | 2013-05-30 |
20130137098 | METHOD OF DNA SEQUENCING BY HYBRIDISATION - Described herein is a method for determining a nucleic acid sequence, said method comprising: a) denaturing a double-stranded nucleic acid molecule corresponding to the said nucleic acid sequence by applying a physical force to the said molecule; b) providing a single-stranded nucleic acid molecule; c) renaturing the said double stranded nucleic acid molecule in the presence of the said single-stranded nucleic acid molecule; and d) detecting a blockage of the renaturation of the double-stranded nucleic acid. | 2013-05-30 |
20130137099 | TRANSGENIC REPORTER SYSTEM THAT REVEALS EXPRESSION PROFILES AND REGULATION MECHANISMS OF ALTERNATIVE SPLICING IN MAMMALIAN ORGANISMS - An object of the present invention is to develop a new alternative splicing reporter system and to provide a method for detecting alternative splicing patterns in a mammalian multicellular organism more precisely, a method for identifying efficiently substances and gene regions that affect alternative splicing in a mammalian multicellular organism, and the like by utilizing the alternative splicing reporter system. Specifically, the present invention relates to a method for detecting alternative splicing in a mammalian multicellular organism, and a method for identifying substances and gene regions that affect alternative splicing in a mammalian multicellular organism, which use a DNA construct in which at least two different reporter genes are inserted into a specific gene that undergoes alternative splicing, or a combination of DNA constructs (a combination of at least two different DNA constructs) in which DNA construct a reporter gene is inserted into a specific gene that undergoes alternative splicing. | 2013-05-30 |
20130137100 | GENETICALLY MODIFIED BACTERIUM OF THE SPECIES LISTERIA MONOCYTOGENES - The present invention relates to a genetically modified bacterium of the species | 2013-05-30 |
20130137101 | Methods of Modifying Eukaryotic Cells - A method for engineering and utilizing large DNA vectors to target, via homologous recombination, and modify, in any desirable fashion, endogenous genes and chromosomal loci in eukaryotic cells. These large DNA targeting vectors for eukaryotic cells, termed LTVECs, are derived from fragments of cloned genomic DNA larger than those typically used by other approaches intended to perform homologous targeting in eukaryotic cells. Also provided is a rapid and convenient method of detecting eukaryotic cells in which the LTVEC has correctly targeted and modified the desired endogenous gene(s) or chromosomal locus (loci) as well as the use of these cells to generate organisms bearing the genetic modification. | 2013-05-30 |
20130137102 | Methods and kits for modulating tumor invasiveness and metastatic potential - Methods and kits for evaluating invasive potential and metastatic potential of cancers by assessing Tiam1 expression levels in fibroblasts in the microenvironments surrounding tumors are provided. | 2013-05-30 |
20130137103 | ANALYSIS - A method of analysing a sample includes providing a first part of the sample and a second part of the sample. A first analysis is conducted on the first part of the sample and the results of the first analysis are considered. A second analysis is conducted on the second part of the sample, the second analysis being conducted according to a procedure using a value for each of one or more characteristics of the procedure. The consideration of the results of the first analysis is used to determine whether the value for one or more of the characteristics of the procedure is changed to a different value. The second analysis is started before the results of the first analysis are obtained. | 2013-05-30 |
20130137104 | METHODS AND COMPOSITIONS FOR MODIFICATION OF THE HPRT LOCUS - Nucleases and methods of using these nucleases for modification of an HPRT locus and for increasing the frequency of gene modification at a targeted locus and clones and for generating animals. | 2013-05-30 |
20130137105 | THERMAL CYCLING USING PHASE CHANGING FLUIDS - The invention provides systems, devices, and methods for heating and cooling chemical or biological samples, such as genetic materials during Polymerase Chain Reaction (“PCR”). The systems, devices, and methods comprise use of a fluid that performs repeated heating and cooling cycles, e.g., ‘thermal cycling’, on sample reactants with a phase changing fluid during evaporation and condensation. The systems, devices, and methods eliminate the need for a heating block as a means to obtain fast and uniform thermal cycling. The disclosure also describes the use of an optical system in conjunction with the thermodynamic cycler for real-time detection. Ultimately, uniformity and speed of the thermodynamic cycler provides for higher sensitivity and throughput of gene replication and detection. | 2013-05-30 |
20130137106 | Tumor Marker and Methods of Use Thereof - Newly identified proteins as markers for the detection of breast, colon, lung and ovary tumors, or as therapeutic targets for their treatment, affinity ligands capable of selectively interacting with the newly identified markers and methods for tumor diagnosis and therapy using such ligands. | 2013-05-30 |
20130137107 | RAPID NUCLEIC ACID PURIFICATION - Provided is a method for rapid nucleic acid purification, and the method for rapid nucleic acid isolation according to the present invention is very useful in diagnosing causes of disease or detecting a target gene; can be used in molecular diagnosis of causes of disease more rapidly and conveniently, as compared with the existing nucleic acid isolation method requiring complicated and special equipment; does not require skills therefor, thereby allowing an ordinary person to personally conduct isolation of nucleic acid for analyzing causes of disease and further solving the existing inconvenience caused by directly going to the hospitals or health clinical centers; and can analyze causes of disease more promptly. | 2013-05-30 |
20130137108 | MAGNETIC BEAD SEPARATION APPARATUS AND METHOD - Disclosed herein is a diffusion-limiting reactor having a first element and a closure element, said reactor having at least two interconnected reservoirs said interconnection being by non-impinging microchannel, and at least one said reservoir and said microchannel being magnetic accessible. Further disclosed is a method of sample separation. | 2013-05-30 |
20130137109 | SYSTEM AND METHOD INCLUDING ANALYTICAL UNITS - Systems and methods for processing and analyzing samples are disclosed. The system may process samples, such as biological fluids, using assay cartridges which can be processed at different processing locations. In some cases, the system can be used for PCR processing. The different processing locations may include a preparation location where samples can be prepared and an analysis location where samples can be analyzed. To assist with the preparation of samples, the system may also include a number of processing stations which may include processing lanes. During the analysis of samples, in some cases, thermal cycler modules and an appropriate optical detection system can be used to detect the presence or absence of certain nucleic acid sequences in the samples. The system can be used to accurately and rapidly process samples. | 2013-05-30 |
20130137110 | SYSTEM AND METHOD INCLUDING ANALYTICAL UNITS - Systems and methods for processing and analyzing samples are disclosed. The system may process samples, such as biological fluids, using assay cartridges which can be processed at different processing locations. In some cases, the system can be used for PCR processing. The different processing locations may include a preparation location where samples can be prepared and an analysis location where samples can be analyzed. To assist with the preparation of samples, the system may also include a number of processing stations which may include processing lanes. During the analysis of samples, in some cases, thermal cycler modules and an appropriate optical detection system can be used to detect the presence or absence of certain nucleic acid sequences in the samples. The system can be used to accurately and rapidly process samples. | 2013-05-30 |
20130137111 | DETECTION METHOD OF NOVEL RET FUSION - It was found that a new fusion gene of a portion of the KIF5B gene and a portion of the RET gene, which is present in a portion of cancer patients, is a gene responsible for cancer. Based on this finding, detection methods of a polynucleotide as the gene and a polypeptide encoded by the polynucleotide were established. The detection methods involve detecting a fusion gene of a portion of the KIF5B gene and a portion of the RET gene, or a fusion protein encoded by such a fusion gene. The primer sets and the detection kits comprise sense primers designed from a portion encoding KIF5B and antisense primers designed from a portion encoding RET. | 2013-05-30 |
20130137112 | DYES FOR ANALYSIS OF PROTEIN AGGREGATION - Provided are dyes and compositions which are useful in a number of applications, such as the detection and monitoring protein aggregation, kinetic studies of protein aggregation, neurofibrillary plaques analysis, evaluation of protein formulation stability, and analysis of molecular chaperone activity. | 2013-05-30 |
20130137113 | Photoreactive Regulator of Protein Function and Methods of Use Thereof - The present invention provides a synthetic regulator of protein function, which regulator is a light-sensitive regulator. The present invention further provides a light-regulated polypeptide that includes a subject synthetic regulator. Also provided are cells and membranes comprising a subject light-regulated polypeptide. The present invention further provides methods of modulating protein function, involving use of light. The present invention further provides methods of identifying agents that modulate protein function. | 2013-05-30 |
20130137114 | Bioprobe, Method of Preparing the Bioprobe, and Analysis Apparatus and Method Using the Bioprobe - The present invention relates to a bioprobe including a substrate and inorganic nanoparticles attached to the surface of the substrate, a method of preparing the bioprobe, and an analysis apparatus and method using the bioprobe. In the bioprobe according to the present invention, inorganic nanoparticles introduced to the substrate serve as a linker to which a target-specific substance such as an antibody can be bound, and they also increase the surface area of the substrate, thus increasing a surface area where a target substance to be detected can contact the substrate. In this regard, the bioprobe can be effectively used for detection, dosing, or analysis of various biomolecules or other chemical substances. | 2013-05-30 |
20130137115 | HOMOGENEOUS DETECTION METHOD - The invention relates to methods for the quantitative or qualitative detection of an analyte in an assay and adequate reagents therefor, particularly a homogeneous binding test. According to the invention, an analyte-specific binding partner R1 comprises more than one specific binding point for a specific binding partner X that is associated with a component of a signal-forming system while a second analyte-specific binding partner R2 comprises more than one specific binding point for a specific binding partner Y which is also associated with a component of a signal-forming system. | 2013-05-30 |
20130137116 | METHOD AND KIT FOR DETECTING THE EARLY ONSET OF RENAL TUBULAR CELL INJURY - A method and kit for detecting the early onset of renal tubular cell injury, utilizing NGAL as an early urinary biomarker. NGAL is a small secreted polypeptide that is protease resistant and consequently readily detected in the urine following renal tubule cell injury. NGAL protein expression is detected predominantly in proximal tubule cells, in a punctate cytoplasmic distribution reminiscent of a secreted protein. The appearance of NGAL in the urine is related to the dose and duration of renal ischemia and nephrotoxemia, and is diagnostic of renal tubule cell injury and renal failure. NGAL detection is also a useful marker for monitoring the nephrotoxic side effects of drugs or other therapeutic agents. | 2013-05-30 |
20130137117 | METHOD FOR PREPARING PROTEIN IMPRINTED POLYMERS AND USE THEREOF - Methods for preparation of molecularly imprinted polymers and their use for detection of proteins and/or polypeptides in a sample are disclosed. The methods of preparation are based on selecting from available data bases an amino acid sequence of a protein/polypeptide target molecule; cleaving the sequence in-silico with at least one cleaving agent, producing fragments with known composition; selecting at least one such fragment comprising a unique epitope; preparing a synthetic peptide representing the unique epitope; and preparing a molecularly imprinted polymer comprising specific binding sites for the synthetic peptide. For detection of the target protein in a sample, the same cleaving agent used for the in-silico cleavage is used to cleave the target protein to form the specific peptide fragments to which the MIP is specific. | 2013-05-30 |
20130137118 | INTEGRIN HETERODIMER AND A SUBUNIT THEREOF - A recombinant or isolated integrin heterodimer comprising a novel subunit α10 in association with a subunit β is described. The α10 integrin may be purified from bovine chondrocytes on a collagen-type-II affinity column. The integrin or the subunit of α10 can be used as a marker or target of all types of cells, e.g. of chondrocytes, osteoblasts, and fibroblasts. The integrin or the subunit α10 thereof can be used as a marker or target in different physiological or therapeutic methods. They can also be used as active ingredients in pharmaceutical compositions and vaccines. | 2013-05-30 |
20130137119 | DETECTION OF BACTERIAL CONTAMINATION IN A SAMPLE - Methods for detecting one or more target bacteria in a test sample are provided. It is shown herein that photosensitizers combined with intense light exposure reduce fluorescing background due to non-bacterial particles. This permits detection of subsequently labeled target bacterial cells (e.g., using a fluorescently labeled antibody) against a largely black background. In particular examples, the methods include incubating the test sample in a growth medium that permits growth of bacteria present in the sample, contacting the sample with a photo-sensitizer; exposing the sample to light under conditions sufficient for the photo-sensitizer to photobleach contaminating non-bacterial particulates present in the sample. The bacteria can then be substantially separated from the sample, thereby generating an isolated bacterial sample. The method can also include contacting the isolated bacterial sample with a binding agent specific for the one or more target bacteria, and detecting the one or more target bacteria. | 2013-05-30 |
20130137120 | AMYLOID B MEASUREMENT METHOD - Disclosed herein is an Aβ measurement method capable of accurately measuring the concentration of Aβ in a sample even when the sample contains a very low level (about several pM) of Aβ. The amyloid β measurement method includes: a sample preparation step | 2013-05-30 |
20130137121 | Method And Device For Assay Determination - A device and method for determining the assay result is disclosed. The device includes a photoelectric detection circuit and a processor, and an optical detection device which is set with a detection zone and a blank zone for measuring assay results, and the photoelectric detection circuit detects the light-reflection intensity signal, and feeds back the detected information to the processor, and the processor is preset with a threshold value changing with time, and determined value processed by the processor is compared with the preset threshold value to obtain the result of assay. The method for determining the assay result display the result when confirmed determined value is bigger than the preset threshold value or can not reach preset threshold value within a fixed time or detected signal can not be determined, wherein the threshold value changes with the time. The device and method for determining the assay result work more efficiently, measure more accurately and cost less than the prior art. | 2013-05-30 |