19th week of 2011 patent applcation highlights part 36 |
Patent application number | Title | Published |
20110110992 | Methods and Compositions for Preventing or Reducing Frizzy Appearance of Hair - Compositions and methods are disclosed for preventing or reducing frizzy appearance of keratin fibers, including hair, and reducing the amount of fly-away strands of hair, particularly in humid conditions, by forming a coating on hair that is resistant to water vapors from the air or surrounding environment. The compositions comprise a combination of a hydrophobic particulate material comprising a hydrophobically surface-modified aluminum oxide and one or more hydrophobic film formers in a cosmetically acceptable vehicle. | 2011-05-12 |
20110110993 | HEPMC - The present application relates to high efficiency particles and compositions, such as consumer products, comprising such high efficiency particles as well as processes for making and using such high efficiency particles and compositions comprising such high efficiency particles. Such high efficiency particles and compositions provide enhanced benefit agent delivery to a situs that is treated with such high efficiency particles and compositions. | 2011-05-12 |
20110110994 | SILICONE COMPOSITE PARTICLES, MAKING METHOD, AND COSMETIC COMPOSITION - Silicone composite particles are provided in which silicone elastomer spherical particles having a volume average particle size of 0.1-100 μm are coated with an organosilsesquioxane-based silicone resin containing inorganic nano-particles having a volume average particle size of up to 100 nm. The silicone composite particles are compounded in a cosmetic composition to exert a UV screening effect or bactericidal property inherent to inorganic nano-particles and to impart a pleasant feel on use. A preparing method and a cosmetic composition are also provided. | 2011-05-12 |
20110110995 | SURFACE-TREATED POWDER AND COSMETIC COMPRISING THE SAME - Provided is a surface-treated powder having excellent usability and adhesion to skin. The powder is coated with a surface-treating agent including (a) a fluorine-containing monomer of a general formula (I) and (b) an alkoxy group-containing monomer of a general formula (II). The powder is used for various cosmetics. | 2011-05-12 |
20110110996 | LAYER COMPOSITE, SUITABLE AS A WOUND DRESSING, COMPRISING A POLYURETHANE FOAM LAYER, AN ABSORBER LAYER AND A COVER LAYER - Layered composite useful as wound dressing, comprising a base layer, an absorbent layer atop the base layer, and also a covering layer, wherein the covering layer is bonded to both the base layer and the absorbent layer and wherein the base layer comprises a polyurethane foam obtained by a composition comprising an aqueous, anionically hydrophilicized polyurethane dispersion that has been frothed and dried. | 2011-05-12 |
20110110997 | BENEFIT AGENT CONTAINING DELIVERY PARTICLE - The present invention relates to benefit agent containing delivery particles, compositions comprising said particles, and processes for making and using the aforementioned particles and compositions. When employed in compositions, for example, personal care, cleaning or fabric care compositions, such particles increase the efficiency of benefit agent delivery, there by allowing reduced amounts of benefit agents to be employed. In addition to allowing the amount of benefit agent to be reduced, such particles allow a broad range of benefit agents to be employed. | 2011-05-12 |
20110110998 | POLYSILOXANE ANTIMICROBIALS - Disclosed are oligo- or polysiloxanes, which are characterized by containing at least 3, for example 4-3000, Si atoms in the main chain, and wherein at least one thereof is contained in a moiety of the formula (I) whose open bond of the O atom is linked to another Si atom of the oligo- or polysiloxane main chain, and whose open bond of the Si atom is linked either to another O atom of the oligo- or polysiloxane main chain or to R′ | 2011-05-12 |
20110110999 | METHOD OF MANUFACTURING NATURAL OR SYNTHETIC FIBERS CONTAINING SILVER NANO-PARTICLES - There is described a method for the deposition of silver nanoparticles on the surface of natural or synthetic textile fibers. | 2011-05-12 |
20110111000 | SURFACE MOUNTABLE DELIVERY DEVICE - There is described a surface mountable delivery device which has a multi layer construction comprising a liquid permeable support layer adjacent to a porous reservoir layer, the porous reservoir layer being provided with a backing layer. The surface mountable delivery device may comprise of stickers, tapes, pads, tubes, socks, etc. | 2011-05-12 |
20110111001 | ACIDIC PROCESSES TO PREPARE ANTIMICROBIAL CONTACT LENSES - This invention relates to antimicrobial lenses containing metals and methods for their production. | 2011-05-12 |
20110111002 | TRANSPORT AND DELIVERY OF GLUTATHIONE INTO HUMAN CELLS USING GOLD NANOPARTICLES - A method of using specially designed a nanoparticles to contact and then cross the cell, nuclear and/or mitochondrial membrane of the target cell by generating a multitude of complex nanoparticle structures that resonate or vibrate at a specific frequency. Glutathione and/or other molecules or drugs are attached as molecular layers to the nanoparticle structures and the complex particle structures are delivered to the targeted cells. The glutathione and other molecules or drugs are then released from the nanoparticle structures in the destination target cell by using external radiation. | 2011-05-12 |
20110111003 | STABLE CELL BINDING CHIMERIC PEPTIDES - The present invention relates to novel family of homologous cell attachment chimeric peptides. In particular, the present invention relates to chimeric peptides, each comprising synthetic peptides comprising (a) an M-tide comprising an amino acid sequence that is at least 80% homologous to the amino acid sequence selected from the group consisting of: SEQ ID NO:1, 2 and 37; and (b) a core haptide comprising an amino acid sequence homologous to amino acid sequences at the carboxy termini of the and E chains of fibrinogen or other proteins comprising C-termini that are homologous to said fibrinogen sequences, wherein the M-tide and the core haptide originate from the same protein. The synthetic peptides are linked to one another thereby providing the chimeric peptides of the invention which does not occur in the native protein as a continuous sequence. The present invention further discloses pharmaceutical compositions comprising said chimeric peptides and uses thereof. | 2011-05-12 |
20110111004 | OSTEOINDUCTIVE NANOCOMPOSITES - The present invention relates porous osteoinductive nanocomposites and for the methods to prepare osteoinductive nanocomposites. The osteoinductive composites consist of biocompatible polymers and non-heated (or non-sintered), needle-shaped or plate-like calcium phosphate nanocrystals and the methods comprise the steps of: a. adding phosphate to a calcium solution thereby evoking precipitation of calcium phosphate nanocrystals; b. washing the nanocrystals with water and suspending them in an organic solvent or getting dry calcium phosphate nanocrystals after evaporating organic solvent; c. adding polymers (previously dissolved in an organic solvent) to calcium phosphate nanocrystal suspension, rotational mixing of the components using beads, mixing with porogenic agents, moulding the composite material and evaporating of the organic solvent; or mixing polymers (not dissolved in an organic solvent but raw powder), dry calcium phosphate nanocrystals and porogenic agents with melting intrusion and moulding the composites; d. leaching porogenic agents in water. | 2011-05-12 |
20110111005 | BIOCOMPATIBLE MATERIAL AND USES THEREOF - The present invention relates to a biocompatible ceramic material comprising Sr, Mg or Ba doped Hardystonite (Ca | 2011-05-12 |
20110111006 | CONVENIENTLY IMPLANTABLE SUSTAINED RELEASE DRUG COMPOSITIONS - This invention provides for biocompatible and biodegradable syringeable liquid, implantable solid, and injectable gel pharmaceutical formulations useful for the treatment of systemic and local disease states. | 2011-05-12 |
20110111007 | INHIBITION OF RETINAL CELL DEGENERATION OR NEOVASCULARIZATION BY CERIUM OXIDE NANOPARTICLES - The presently claimed and disclosed inventive concept(s) provides methods for reducing, reversing or inhibiting retinal cell degeneration, or neovascularization in tissues of a mammalian subject having a pathological condition involving neovascularization, by administration in vivo of nanoceria particles (cerium oxide nanoparticles) to the subject. The method of the presently claimed and disclosed inventive concept(s) is useful, for example, for reducing, treating, reversing or inhibiting degeneration of retinal cells such as photoreceptor cells or neovascularization in ocular tissue such as the retina, macula or cornea; or other tissues such as, but not limited to, skin, synovial tissue, intestinal tissue, or bone. In addition, the method of the presently claimed and disclosed inventive concept(s) is useful for reducing or inhibiting neovascularization in a neoplasm (tumors), which can be benign or malignant and, where malignant, can be a metastatic neoplasm. As such, the presently claimed and disclosed inventive concept(s) is directed to using compositions containing nanoceria particles to reduce, treat, reverse or inhibit angiogenesis in a mammalian subject. | 2011-05-12 |
20110111008 | Use of PEDF in an Encapsulated Cell-Based Delivery System - The invention relates to a device for delivery of pigment epithelium derived factor (PEDF) to the eye utilizing encapsulated PEDF-secreting cells and related methods for the treatment and prevention of ophthalmic diseases and disorders. | 2011-05-12 |
20110111009 | METHODS AND FORMULATIONS FOR ENHANCING THE ABSORPTION AND DECREASING THE ABSORPTION VARIABILITY OF ORALLY ADMINISTERED DRUGS, VITAMINS AND NUTRIENTS - A method of preparing and composition of bioavailable hydrophobic, poorly water soluble drugs. It uses for example, lecithin, sterol, a calcium salt, and solvent; mixing to form liposomes and then the solvent driven off; the ratios used and physical form differ from others, and maximize performance. | 2011-05-12 |
20110111010 | Method and Composition for Burned Skin - The present invention is directed to the use of an agent selected from ethyl alcohol, isopropyl alcohol or a mixture thereof and a topically acceptable polymeric carrier in the preparation of a composition for the treatment of burns. | 2011-05-12 |
20110111011 | SUBLINGUAL APOMORPHINE - The invention features sublingual formulations of apomorphine and apomorphine prodrugs, and methods of treating Parkinson's disease, sexual dysfunction, and depressive disorders therewith. | 2011-05-12 |
20110111012 | Nanomaterial wound dressing assembly - Wound dressing assemblies and methods of producing the wound dressing assemblies. The wound dressing assemblies various comprise individual layers of nanomaterials that have been formed according to an electrospinning process. | 2011-05-12 |
20110111013 | TRANSDERMAL THERAPEUTIC SYSTEM FOR ADMINISTRATION OF FENTANYL OR AN ANALOGUE THEREOF - What is disclosed is a transdermal therapeutic system for administration of an active ingredient through the skin, comprising: (a) a back layer, (b) a reservoir present on the back layer, comprising the active ingredient, polyisobutylene, a gel former and a plasticizer, a portion of the active ingredient in the reservoir being present in the form of undissolved particles and the content of gel formers in the reservoir being at most 4% by weight (based in the total weight of the reservoir), the active ingredient being Fentanyl or an analogue thereof. | 2011-05-12 |
20110111014 | METHODS AND COMPOSITIONS FOR TREATMENT OF NEUROLOGICAL DISORDERS - Methods and compositions are provided for preventing and treating neurological disorders, in particular Parkinson's disease. | 2011-05-12 |
20110111015 | COMPOSITIONS AND METHODS OF ENHANCING IMMUNE RESPONSES TO EIMERIA - Vaccines comprising TRAP polypeptides and | 2011-05-12 |
20110111016 | NON-DNA BASE-CONTAINING POLYNUCLEOTIDE COMPOSITIONS AND THEIR USE FOR THE MODULATION OF IMMUNE RESPONSES - The present invention provides compositions comprising synthetic non-DNA base-containing polynucleotide sequences of 3 to 30 bases in length comprising one or more non-DNA bases wherein the bases are nebularine, hypoxanthine, or uracil, or combinations of nebularine, hypoxanthine and uracil bases, in combination with a pharmaceutically acceptable vehicle, particularly one or more adjuvant vehicle, and one or more antigen. The present invention relates to methods of administering these compositions for inducing or modulating an immune response in vitro or in vivo, and particularly for activating antigen presenting cells. | 2011-05-12 |
20110111017 | USE OF IMMUNOGENIC COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF PATHOGEN INFECTIONS - The invention provides compositions featuring cationic liposome nucleic acid molecules complexed with pathogen derived antigen and methods of using such compositions for the treatment or prevention of an infectious disease. Other features and advantages of the invention will be apparent from the detailed description, and from the claims. | 2011-05-12 |
20110111018 | COATED TABLET FORMULATIONS AND USES THEREOF - The present invention provides coated tablet formulations comprising neratinib maleate, and improved methods for making such coated tablets. | 2011-05-12 |
20110111019 | Novel Method for Producing Nanocapsules in the Absence of an Organic Solvent, and Nanocapsules Produced Thereby - The invention relates to a method for preparing an aqueous suspension of nanocapsules comprising an oily core surrounded by a polymeric shell, in which method the following phases are mixed:
| 2011-05-12 |
20110111020 | Microcapsules Having Multiple Shells and Method for the Preparation Thereof - Single-core and multi-core microcapsules are provided, having multiple shells, at least one of which is formed of a complex coacervate of two components of shell materials. The complex coacervate may be the same or different for each shell. Also provided are methods for making the microcapsules. | 2011-05-12 |
20110111021 | PHARMACEUTICAL PREPARATION - The present invention provides a pharmaceutical preparation including a compartment containing a renin inhibitor as a pharmacologically active ingredient, and a compartment containing an HMG-CoA reductase inhibitor as a pharmacologically active ingredient, wherein one compartment is a prior-release compartment and the other compartment is a delayed-release compartment. The combination preparation of the present invention can deliver a renin inhibitor and an HMG-CoA reductase inhibitor with a time interval at a specific speed, thus reducing undesirable side-effects, improving the drug efficacy and promoting the patient compliance. Further, the pharmaceutical preparation of the present invention has pharmacological, clinical, scientific and economical advantages in the prevention or treatment of metabolic syndromes, cardiovascular diseases, renal diseases and the like, as compared with the complex drug regimens in which medicament ingredients are taken individually or simultaneously. | 2011-05-12 |
20110111022 | PHARMACEUTICAL FORMULATION - The present invention provides a pharmaceutical formulation comprising a compartment containing a rennin inhibitor as a pharmacologically active ingredient, and a compartment having an angiotensin-II-receptor blocker as a pharmacologically active ingredient. One of the compartments is an immediate-release compartment and the other one is an extended-release compartment. Since the disclosed formulation delivers the rennin inhibitor and angiotensin-II-receptor blocker at a specific delivery rate at a different time. It has an advantage in reducing the concern about side effects, improving drug effects, and simplifying the instructions for use of the drug. In addition, the formulation can pharmacologically, clinically, scientifically, and economically achieve more useful effects than the complex prescription case of taking the ingredients separately or each at once, in preventing and treating metabolic syndrome, cardiovascular disease and renal disease. | 2011-05-12 |
20110111023 | PREVENTION OF TYPE 1 DIABETES BY ADMINISTRATION OF GLIADIN - The invention herein is related to intranasal or other mucosal administration of gliadin, or parts thereof, to prevent the development of type 1 diabetes. This environmental antigen, which may have etiological role in the development of diabetes in genetically predisposed individuals, has been successfully applied in the prevention of disease. | 2011-05-12 |
20110111024 | PHARMACEUTICAL COMPOSITIONS AND ORAL DOSAGE FORMS OF A LEVODOPA PRODRUG AND METHODS OF USE - Pharmaceutical compositions and oral dosage forms of (2R)-2-phenylcarbonyloxypropyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate mesylate and methods of treating diseases comprising orally administering such pharmaceutical compositions and dosage forms are disclosed. | 2011-05-12 |
20110111025 | High Drug Load Formulations and Dosage Forms - The invention relates to high drug load formulations containing (R)-2-(2-fluoro-4-biphenylyl)propionic acid as an active pharmaceutical ingredient. | 2011-05-12 |
20110111026 | HUMIDITY-RESISTANT DRUG FORMULATIONS AND METHODS OF PREPARATION THEREOF - The invention relates to a pharmaceutical composition of a humidity-sensitive core comprising an active ingredient or pharmaceutically acceptable salt thereof; a coating over the core, the coating containing a cationic polymer; and an additional coating over the cationic polymer-containing coating, with the additional coating including an acidifying agent. Also, methods for preparing such compositions wherein a cationic polymer containing coating is applied over a humidity-sensitive core that contains the active ingredient or pharmaceutically acceptable salt thereof; and then an additional coating is applied over the cationic polymer containing coating. | 2011-05-12 |
20110111027 | IMMEDIATE RELEASE FORMULATIONS AND DOSAGE FORMS OF GAMMA-HYDROXYBUTYRATE - The present invention provides a solid immediate release dosage form adapted for oral administration of GHB. The solid immediate release dosage form includes an immediate release formulation comprising a relatively high weight-percentage of GHB with a bioavailability similar to that of a liquid GHB dosage form. | 2011-05-12 |
20110111028 | Composition and Methods For Repair of Connective Tissue - Compositions and methods for repairing a ruptured connective tissue are disclosed. The composition may include a first biocompatible material to provide a scaffold for connective tissue cell growth and tissue repair. This first biocompatible material may withstand a tensile load of up to 250 N. The composition may also include a second biocompatible material including at least one bioactive agent that can stimulate connective tissue cell growth and tissue repair. The method may include positioning a first end of the first biocompatible material adjacent a first end of a ruptured connective tissue, positioning a second end of the first biocompatible material adjacent a second end of the ruptured connective tissue, and anchoring the first biocompatible material to the first and second tendon ends. The method may alternatively comprise or further include positioning a second biocompatible material between the first and second ends of the ruptured connective tissue. | 2011-05-12 |
20110111029 | COMPOSITION FOR TRANSDERMAL DELIVERY OF CATIONIC ACTIVE AGENTS - A composition for transdermal delivery, particularly iontophoretic transdermal delivery, having at least one cationic active agent or a salt thereof. The composition comprises at least one cationic active agent or a salt thereof, at least one polyamine and/or polyamine salt, water or an aqueous solvent mixture, and optionally one or more additives. Use of the composition as a component of a transdermal patch or of an iontophoretic transdermal patch is also provided, as well as the use of the composition in a method for transdermally or iontophoretically administering cationic active agents. A method for determining the in vitro skin permeation properties of an active agent-containing iontophoretic composition is also provided. | 2011-05-12 |
20110111030 | Method of Producing Progenitor Cells from Differentiated Cells - The present invention provides a method of producing progenitor cells, such as cells capable of being differentiated into a plurality of different cell types, from differentiated cells. Methods of using progenitor cells in differentiation and/or tissue or organ repair and/or regeneration and/or building are also provides. Methods of using progenitor cells in treatment and prophylaxis of conditions alleviated by administering stem cells or tissue or organ derived from stem cells to a subject or by grafting stem cells or tissue or organ derived from stem cells into a subject or by transplanting stem cells or tissue or organ derived from stem cells into a subject are also provided. Also included are progenitor cells and differentiated cells and/or tissues and/or organs derived therefrom, and kits comprising same. | 2011-05-12 |
20110111031 | Drug Delivery Platforms Comprising Silk Fibroin Hydrogels and Uses Thereof - The present specification provides drug delivery platforms useful for the controlled release of a compound over time in an individual. | 2011-05-12 |
20110111032 | MANUFACTURING METHOD OF COLLAGEN GEL COMPOSITION FOR BONE REGENERATION - Disclosed herein is a method for preparing a collagen gel composition for bone regeneration comprising collecting bone marrow from animal tissues and isolating nucleated cells from the bone marrow; and mixing the nucleated cells and a bio-matrix composed of type I collagen and apatite. | 2011-05-12 |
20110111033 | HYDROGEL WITH COVALENTLY CROSSLINKED CORE - A novel hydrogel system is provided. The hydrogel system comprises a biocompatible hydrogel core having dispersed therein a covalently crosslinked polymer matrix. The hydrogel system is useful per se or as an encapsulation system. | 2011-05-12 |
20110111034 | METHOD AND MATERIAL FOR ENHANCED TISSUE-BIOMATERIAL INTEGRATION - The present invention relates to the covalent binding of a hydrogel to an extracellular matrix (ECM). The integration of the hydrogel with the tissue is superior to that in previous techniques. Moreover, unlike previous techniques, the present invention does not require a photoinitiator. Potential therapeutic applications include tissue repair and delivery of drugs or cells. | 2011-05-12 |
20110111035 | INFLAMMATION-REGULATING COMPOSITIONS AND METHODS - The various embodiments provide a composition that provides local control over inflammation. The composition localizes the activities of the cytokine-neutralizing antibodies to the site of inflammation through covalent attachment to hydrophilic matrices. The various embodiments including a hydrophilic polymer, a ligand binding moiety covalently attached to the polymer, and optionally, a cellular adhesion peptide covalently attached to the polymer. The hydrophilic polymer may be a glycosaminoglycan such as hyaluronan. The cellular adhesion peptide may be a linear RGD peptide sequence covalently attached to the polymer. The ligand binding moiety may be a monoclonal antibody covalently attached to the polymer. The antibody may be selected from the group consisting of an anti-IL-1β, an anti-IL-6, an anti-TNF-α, and combinations thereof. The polymer functions as a substrate or matrix for cell migration and tissue regeneration. The RGD peptide functions to promote cellular proliferation, migration and attachment to the polymer. The monoclonal antibody functions to inhibit the inflammatory response. | 2011-05-12 |
20110111036 | INTRACELLULAR ANTIBODY DELIVERY - The present invention concerns a composition comprising vesicles and encapsulated within the vesicles, an antibody, wherein the vesicles comprise an amphiphilic block copolymer having a hydrophilic and a hydrophobic block. | 2011-05-12 |
20110111037 | ORODISPERSIBLE MANNITOL - Coagglomerates of mannitol, whose laser volume-average diameter D4,3 is between 1 and 200 μm, and of granular starch, are characterized in that they have a disintegration behaviour determined according to a test A such that the relaxation time measured is between 30 and 100 seconds and the swelling force is between 0.8 and 3.0 N. | 2011-05-12 |
20110111038 | PROCESS FOR PRODUCING A STABLE CONCENTRATED DIETARY SUPPLEMENT AND SUPPLEMENT PRODUCED THEREBY - A stable concentrated dietary supplement containing fucoxanthin as the main active component. The dietary supplement is made by a process including grinding crude freeze-dried flakes of wakame seaweed ( | 2011-05-12 |
20110111039 | Compositions and Methods for Inhibiting Gastric Acid Secretion - The present invention is related to novel oral compositions comprising an irreversible gastric H | 2011-05-12 |
20110111040 | POLYELECTROLYTE-ENCAPSULATED GOLD NANOPARTICLES CAPABLE OF CROSSING BLOOD-BRAIN BARRIER - A gold-creatine nanoparticle is described, preferably covered with albumin, together with a process for its preparation and its use as medicament, in particular for the treatment of stroke. Said gold nanoparticle is capable of crossing the blood-brain barrier. | 2011-05-12 |
20110111041 | BACTERIALLY DERIVED INTACT MINICELLS THAT ENCOMPASS PLASMID FREE FUNCTIONAL NUCLEIC ACID FOR IN VIVO DELIVERY TO MAMMALIAN CELLS - Intact, bacterially-derived minicells can safely introduce therapeutically effective amounts of plasmid-free functional nucleic acid to target mammalian cells. To this end, functional nucleic acid can be packaged into intact minicells directly, without resort to expression constructs, the expression machinery of the host cell, harsh chemicals or electroporation. | 2011-05-12 |
20110111042 | SELF-MICROEMULSIFYING SYSTEMS INCORPORATED INTO LIQUID CORE MICROCAPSULES - The invention provides a microcapsule having a shell and a liquid core incorporating a self-microemulsifying system or a microemulsion, wherein the core comprises a lipophilic substance, at least one surfactant, an active agent, a gelling agent and optionally a cosolvent. Furthermore, a method for producing such microcapsules and pharmaceutical formulations comprising such microcapsules is provided. | 2011-05-12 |
20110111043 | PEPTIDES AND THEIR USE AS CARRIERS INTO CANCER CELLS - The use of a peptide is described as a carrier for the transport of molecules or radioisotopes into cancer cells; also described are modifications of said peptide and their use. | 2011-05-12 |
20110111044 | NANOPARTICLE COMPOSITIONS FOR NUCLEIC ACIDS DELIVERY SYSTEM - The present invention is directed to nanoparticle compositions for the delivery of oligonucleotides and methods of modulating an expression of a targeted gene using the nanoparticle compositions. In particular, the invention relates to oligonucleotides encapsulated in a mixture of a cationic lipid, a fusogenic lipid and a PEG lipid. | 2011-05-12 |
20110111045 | Pharmaceutical composition for preventing and treating cell proliferative disease comprising mixture of feather of birds and scale of fish as an active ingredient - The present invention relates to a pharmaceutical composition for preventing and treating cell proliferative diseases comprising a feather of birds and a scale of fish, a scale transformed from the dermis, a degenerated or cornified variant of a scale, or a scale or horny scale of reptiles as an active ingredient. More particularly, the present invention relates to a pharmaceutical composition for preventing and treating cell proliferative diseases comprising a mixture of 70-85 weight % of a feather of birds and 15-30 weight % of a scale of fish, a scale transformed from the dermis, a degenerated or cornified variant of a scale, or a scale or horny scale of reptiles as an active ingredient. The inventive composition has the effect of inhibiting and preventing growth of cancer cells. Accordingly, the inventive composition may be used for anticancer purposes to prevent, ameliorate or treat cancer. | 2011-05-12 |
20110111046 | N1-Pyrazolospiroketone Acetyl-CoA Carboxylase Inhibitors - The invention provides a compound of Formula (I) | 2011-05-12 |
20110111047 | COMBINATION PREPARATION OF A BIOLOGICAL RESPONSE MODIFIER AND AN ANTICANCER AGENT AND USES THEREOF - The present invention provides anticancer biological response modifier combinations. In accordance with an aspect of the present invention, there is provided a combination comprising: (i) a composition comprising small molecular weight components of less than 3000 daltons, and having the following properties: is extracted from bile of animals; is capable of stimulating monocytes and/or macrophages in vitro and/or in vivo; is capable of modulating tumor necrosis factor production and/or release; contains no measurable level of IL-1α, IL-1β, TNF, IL-6, IL-8, IL-4, GM-CSF or IFN-gamma; is not cytotoxic to human peripheral blood mononuclear cells; is not an endotoxin; and (ii) one or more anticancer agent(s), wherein said combination has therapeutic synergy or improves the therapeutic index in the treatment of cancer over the composition or the anticancer agent(s) alone. Another aspect of the present invention provides the use of this combination in the manufacture of a medicament or a pharmaceutical kit and in the treatment of cancer. | 2011-05-12 |
20110111048 | PRODUCING METHOD FOR LIVING ORGANISM-APPLICABLE HYDROGEN-CONTAINED FLUID AND PRODUCING APPARATUS FOR THE SAME - A producing method for a living organism-applicable hydrogen-contained fluid, which includes hydrogen molecules in living organism-applicable fluid enclosed in a container ( | 2011-05-12 |
20110111049 | Ischemia/reperfusion protection compositions and methods of using - The invention provides for ischemia/reperfusion protection compositions having one or more ketone bodies and melatonin. The invention also provides for methods of using such compositions to reduce or prevent ischemia/reperfusion injury due to blood loss, stroke or cardiopulmonary arrest or surgery. | 2011-05-12 |
20110111050 | Herbal medicinal composition and herbal medicinal extract for inducing production of peripheral blood stem cells and method for preparing the same - A herbal medicinal composition and a herbal medicinal extract for inducing production of peripheral blood stem cells and a method for preparing the same. The herbal medicinal composition contains herbal medicinal herbs disclosed herein such as Cinnamomum Ramulus, Paeoniae (Ovatae) Radix Rubra, Glycyrrhizae Radix, Zingiberis Rhizoma, Jujubae Fructus, Anelicae Radix, and Astragali Radix. | 2011-05-12 |
20110111051 | PROPHYLACTIC OR ALLEVIATING AGENT FOR PERIPHERAL NERVE DISORDER INDUCED BY ANTI-CANCER AGENT - There is provided a medicinal agent that is effective and highly safe for the prevention or alleviation of a peripheral nerve disorder that develops as a side effect occurring after the administration of an anti-cancer agent. The present invention relates to a novel medical use of an extract from inflamed tissues inoculated with vaccinia virus, and to a prophylactic or alleviating agent for a peripheral nerve disorder that contains the extract as an active ingredient. The agent containing the extract as an active ingredient is used for a prophylactic or alleviating agent for a peripheral nerve disorder induced by an anti-cancer agent and is a highly safe and remarkably highly useful medicinal agent with few side effects. | 2011-05-12 |
20110111052 | Method to generate a mixture of hydrogen peroxide gas and a carrier gas - This relates to a method to generate a mixture of Hydrogen Peroxide gas and a Carrier gas, consisting in passing a dry Carrier gas through a solution of Hydrogen Peroxide. | 2011-05-12 |
20110111053 | ANTIMICROBIAL AGENT - The present invention provides a method of killing and/or inactivating microbes, the method comprising the step of placing the microbes in contact with a catalyst by means of a fluid medium, wherein the catalyst comprises a solid support, which solid support comprises one or more fibres, and a first metal cation fixed to the support. The fibres are keratinous fibres like wool fibres, or polyacrylonitrile (PAN) fibres. The first metal cation is selected from transition metal copper, silver and gold included. A second non-transition metal cation can be present. The catalyst is prepared by first treating the fibres with hydrazine and/or hydroxylamine salt in presence of a base, the modified fibres are then treated with an aqueous solution of containing the metal cations. | 2011-05-12 |
20110111054 | BMP-7 FOR USE IN TREATING VASCULAR SCLEROSIS - The present invention relates to prevention and treatment of vascular sclerosis, vascular calcification (VC) and neointimal hyperplasia using a morphogen. | 2011-05-12 |
20110111055 | NUTRITIONAL SUPPLEMENTS FOR RELIEF OF DRY EYE - The present invention provides improved dietary supplements and methods for alleviating the symptoms of dry eye. The dietary supplements of the invention contain omega-3 fatty acids and flavonoids. | 2011-05-12 |
20110111056 | PEPTIDE DICER SUBSTRATE AGENTS AND METHODS FOR THEIR SPECIFIC INHIBITION OF GENE EXPRESSION - This invention relates to compounds, compositions, and methods useful for reducing a target RNA and protein levels via use of Dicer substrate siRNA (DsiRNA)-peptide conjugates. | 2011-05-12 |
20110111057 | Methods and Compounds Useful to Induce Apoptosis in Cancer Cells - The present invention provides a method for treating cancer in a mammal comprising contacting the cancer cells with a compound which is a apogossypol, derivative. | 2011-05-12 |
20110111058 | METHODS FOR INCREASING THE STABILIZATION OF HYPOXIA INDUCIBLE FACTOR-1 ALPHA - Disclosed herein are methods for controlling the activity of hypoxia-inducible transcription factor 1-alpha (HIF-1α) and diseases, conditions, or syndromes related thereto, inter alia, Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, and anemia. Further disclosed are pharmaceutical compositions comprising HIF-1α prolyl hydroxylase inhibitors useful in treating diseases, conditions, and/or syndromes related thereto the activity of HIF-1α. | 2011-05-12 |
20110111059 | Compositions Comprising Quinazoline Derivatives, Preparation Methods and Uses Thereof - The present invention provides a pharmaceutical composition, useful for the treatment of diseases characterized by abnormal PTKs activity of erbB family in a mammal, comprising pharmaceutically acceptable salts of N-{4-[3-chloro-4-(3-fluoro-benzyloxy)phenylamino]quinazolin-6-yl}-acrylamide, optionally a pharmaceutically applicable carrier or diluent, and a stabilizer having a dispersing and/or protective effect on the active ingredient. The present invention further provides a pharmaceutical formulation comprising said composition, methods for preparation of said composition and said formulation, as well as use of said composition and said formulation for treating diseases characterized by abnormal PTKs activity of erbB family in a mammal. | 2011-05-12 |
20110111060 | COMPOSITIONS, FORMULATIONS, AND METHODS FOR PREVENTING AND/OR TREATING PHYSICAL EFFECTS OF ALCOHOL CONSUMPTION - The present invention provides effective novel compositions and formulations for treating and/or preventing a hangover. The present invention also provides methods for treating and/or preventing a hangover comprising administering the compositions and/or formulations of the present invention. | 2011-05-12 |
20110111061 | Compositions and Methods for the Treatment of Skeletal Metastatic Lesions and Fractures - Compositions and methods for the treatment of fracture and metastatic bone cancer are disclosed. | 2011-05-12 |
20110111062 | LEVODOPA PRODRUG MESYLATE, COMPOSITIONS THEREOF, AND USES THEREOF - (2R)-2-Phenylcarbonyloxypropyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate mesylate and crystalline form thereof, methods of making the same, pharmaceutical compositions thereof, and methods of using the same to treat diseases or disorders such as Parkinson's disease are provided. | 2011-05-12 |
20110111063 | Extended Moisturization Cosmetic Compositions - A cosmetic composition providing a skin moisturizing effect over extended periods of time when applied to skin in need thereof is provided. The composition comprises a skin moisturizing sufficient amount of an extract of an air plant in combination with a cosmetically or dermatologically acceptable carrier. Also provided is a method for providing a skin moisturizing effect over extended periods of time. The method comprises applying to the skin in need of a skin moisturizing effect, a composition comprising a skin moisturizing sufficient amount of an extract of air plant in combination with a cosmetically or dermatologically acceptable carrier. | 2011-05-12 |
20110111064 | Anti-Influenza Virus Agent, Anti-RS Virus Agent, and Anti-Immunodeficiency Virus Agent - The present invention herein provides an anti-influenza virus agent, an anti-RS virus agent or an anti-immunodeficiency virus agent, which comprises components originated from plants and which has excellent infectivity-inhibitory effect and proliferation-inhibitory effect against influenza viruses, RS viruses and immunodeficiency viruses. The anti-influenza virus agent, anti-RS virus agent or anti-immunodeficiency virus agent of the present invention comprises an extract derived from, or dry powder of the leaves of a plant belonging to the family Betulaceae and/or a plant belonging to the family Meliaceae. | 2011-05-12 |
20110111065 | Low Temperature Ultrasonic Extraction Method for Plants - A low temperature ultrasonic extraction method for plants includes the steps grinding a plant material to obtain plant pieces; immersing the plant pieces in low temperature water for a predetermined time; processing the plant pieces with ultrasonic in the low temperature water to obtain a low temperature extract liquid; and filtering the low temperature extract liquid to remove plant fibers from the extract liquid. | 2011-05-12 |
20110111066 | METHOD AND COMPOSITION FOR IMPROVED ANABOLISM - Nutritional compositions are provided containing at least one PPAR agonist, at least one PGC-1alpha agonist, and at least one creatine derivative. Methods of promoting anabolism and improving or enhancing physical performance using the compositions are provided. The compositions and methods can be combined with physical training or exercise. | 2011-05-12 |
20110111067 | ORAL HERBAL COMPOSITION FOR THE TREATMENT OF ORAL CANDIDIASIS - An oral herbal composition comprising a therapeutically effective amount of an extract derived from the berries of a plant, | 2011-05-12 |
20110111068 | Inhibitors of cognitive decline - Compounds that are central nervous system drug candidates for the treatment of cognitive decline and, more particularly, Alzheimer's disease are provided. Methods of treating, inhibiting, and/or abatement of cognitive decline and Alzheimer's disease with a derivative of ginger oil are also provided. Also provided is a method of conditioning biological extracts, such as a medicinal plant extract, by a reductive amination process to give nitrogen-containing derivatives. | 2011-05-12 |
20110111069 | COMPOSITIONS THAT LOWER CYTOSOLIC NADH LEVEL TO MIMIC CALORIE RESTRICTION FOR LIFE EXTENSION AND METHODS - Embodiments herein relate to agents that mimic calorie restriction (CR) to extend life span, especially agents that lower the level of cytosolic NADH and increase the level of cytosolic NAD+ (relative to NADH) required to mimic calorie restriction that results in life span extension, at least in part by inhibition by NADH of SIR2, which is a key regulator of life span in both yeast and animals. NADH is a competitive inhibitor of SIR2, an NAD-requiring NAD-dependent histone deacetylase required for chromatin silencing and life-span extension. An overall reduction in NADH activates SIR2 and extends life span. The use of fluorescence measurements of NADH levels in a 96-well plate assay utilizing Baker's yeast ( | 2011-05-12 |
20110111070 | USE OF PHY906 AS TREATMENT FOR INFLAMMATORY BOWEL DISEASE AND/OR IRRITABLE BOWEL SYNDROME - The present invention includes a method of using PHY906 for treating a bowel disorder including inflammatory bowel disease and irritable bowel syndrome. Particularly, the present invention provides a multiple symptoms treatment for the bowel disorder. | 2011-05-12 |
20110111071 | EFFECTS OF DICHROSTACHYS GLOMERATA DG, HYPODAPHNIS ZENKERI HZ, AND XYLOPIA AETHIOPICA XA ON VARIOUS CARDIOVASCULAR RISK FACTORS AND METABOLIC SYNDROME - Methods of improving a variety of health related factors including, but not limited to weight, cholesterol levels, triglyceride levels and HDL levels, is provided. In one embodiment, a method of reducing LDL cholesterol levels of a mammal in need thereof is provided, the method comprises administering a composition containing an effective amount of | 2011-05-12 |
20110111072 | METHODS FOR PREVENTING AND TREATING NEURODEGENERATIVE DISEASES - The present invention provide a method for the prevention and treatment of a neurodegenerative disease including Alzheimer's Disease, Huntington's Disease, and Parkinson's Disease, using a grape seed extract or one or more compounds derived therefrom. In particular, the present invention provides a method to treat a patient diagnosed with, or at the risk of developing, a neurodegenerative disease by administering a pharmaceutical composition comprising a grape seed extract or one or more compounds derived therefrom to the patient in a therapeutic amount to reduce the accumulation, aggregation or deposition of amyloid beta or its oligomers, and/or to reduce the misfolding, accumulation and/or aggregation of tau proteins or other proteins. | 2011-05-12 |
20110111073 | RECOVERY OF HYDROPHOBIC PEPTIDES FROM OILS - Methods for separation and recovery of individual cyclic peptides from plant materials, said method comprising the steps of: (a) extracting an oil from a plant material; (b) separating the extracted oil into a non-polar fraction and a polar fraction; (c) separation and recovery of cyclic peptides from the non-polar fraction, and (d) separation and recovery of cyclic peptides from the polar fraction. The methods are suitable for separation and recovery of individual cyclolinopeptides from flax seed oil. Individual cyclolinopeptides are useful for modulation physiological disorders associated with apoptosis. Modified flaxseed oils may be produced by comingling flaxseed oils absent cyclolinopeptides, with at least one cyclolinopeptide separated and recovered with the methods disclosed herein. | 2011-05-12 |
20110111074 | MEDICINE TO TREAT DRUG ADDICTION AND PREPARATION METHOD THEREOF - The present invention declares a pharmaceutical extract, composition that has effect to treat drug addiction, and its preparation method and quality control method. This extract is extracted from Radix Stephaniae Epigaeae. Starting medicine material of said composition is Radix Ginseng, Radix Astragali, Rhizoma Corydalis, Radix Angelicae Sinensis and Radix Ophiopogonis; and said composition also can prepared by ethanol extract of Radix Ginseng, ethanol extract of Radix Angelicae Sinensis, total alkaloids of Radix Stephaniae Epigaeae, water extract of Radix Astragali and water extract of Radix Ophiopogonis. Quality control method of said pharmaceutical composition includes one of or several of identifications and content determinations. The present invention also declares the use of said pharmaceutical extract, composition in the preparation of a medicine to treat drug addiction. | 2011-05-12 |
20110111075 | TIRE MOLD WITH POSITIVE MOLD OPENING SYSTEM - A curing mold includes an upper mold portion having a plurality of upper and lower sections radially translatable between open and closed positions, wherein each of the lower sections are positioned adjacent one of the upper sections to form a plurality of pairs of upper and lower sections. The tire mold also includes a pin extending from a first section of each pair of sections, and an aperture extending within a second section of each pair of sections, the aperture including an opening and positioned for receiving a portion of the pin extending from the corresponding first section when the mold is in a substantially closed position. Particular embodiments of the present invention also include a first plurality of radially translatable sections arranged to form an expandable ring and one or more first synchronization members extending between adjacent sections of the first plurality of sections. | 2011-05-12 |
20110111076 | Solar Cell Fabrication Using Extruded Dopant-Bearing Materials - Wafer-based solar cells are efficiently produced by extruding a dopant bearing material (dopant ink) onto one or more predetermined surface areas of a semiconductor wafer, and then thermally treating the wafer to cause diffusion of dopant from the dopant ink into the wafer to form corresponding doped regions. A multi-plenum extrusion head is used to simultaneously extrude interdigitated dopant ink structures having two different dopant types (e.g., n-type dopant ink and p-type dopant ink) in a self-registered arrangement on the wafer surface. The extrusion head is fabricated by laminating multiple sheets of micro-machined silicon that define one or more ink flow passages. A non-doping or lightly doped ink is co-extruded with heavy doped ink to serve as a spacer or barrier, and optionally forms a cap that entirely covers the heavy doped ink. A hybrid thermal treatment utilizes a gaseous dopant to simultaneously dope exposed portions of the wafer. | 2011-05-12 |
20110111077 | Valve gate assembly - A valve gate assembly for regulating a flow of molten material into a mold. The valve gate assembly includes a movable valve that can be positioned between a fully closed position and a fully open position. The valve gate assembly further includes an actuating system operatively cooperating with the valve to move the valve and infinitely position the valve between the fully closed position and the fully open position. | 2011-05-12 |
20110111078 | EXTRUSION HEAD FOR PLASTIC MATERIALS - An extrusion head for plastic materials. The extrusion head is characterized in that a distribution plate is interchangeable. The distribution plate includes at least one distribution network for the extruded materials, so as to determine the characteristics of at least one type of type produced by the extrusion operation through its conformation. | 2011-05-12 |
20110111079 | MOLD STACK FOR A PREFORM - According to embodiments of the present invention, there is provided a stripper assembly and a mold stack incorporating same. More specifically, there is provided the stripper assembly ( | 2011-05-12 |
20110111080 | Mold Structure For Injection Molding - A mold structure has a first die, and a second die. A first buckling element is protruded downwardly from the first die, and defines a first contact surface and a bottom surface. The bottom surface has an end adjacent to the first contact surface protruded downwards to form a jamming portion, and the other end protruded downwards to form a blocking portion spaced away from and beyond the jamming portion. The jamming portion has a triangle cross-section, with a point facing downwardly and away from the blocking portion. A second buckling element is extended upwards from the second die, and has a gap at a top end thereof and passing through a side thereof. The gap defines a second contact surface, corresponding to the first contact surface, and an inclining surface, intersecting with the second contact surface with an acute angle formed therebetween for engaging with the jamming portion. | 2011-05-12 |
20110111081 | AL-ZN-MG ALLOY PRODUCT WITH REDUCED QUENCH SENSITIVITY - This relates to an aluminum alloy product, in particular an age-hardenable Al—Zn—Mg type alloy product for structural members, the alloy product combining a high strength with high toughness and reduced quench sensitivity, and having a chemical composition including, in wt. %: Zn about 3 to 11%, Mg about 1 to 3%, Cu about 0.9 to 3%, Ge about 0.03 to 0.4%, Si max. 0.5%, Fe max. 0.5%, balance aluminum and normal and/or inevitable elements and impurities. Furthermore, this relates to a method of producing such aluminum alloy products. | 2011-05-12 |
20110111082 | RESIN MOLDING DEVICE - A resin molding device includes a lead plate and a first resin molding member. The lead plate includes patterns. Each of the patterns includes a base, a plurality of lead pairs; and a lead connection portion. Each of the lead pairs includes a first lead and a second lead. The first resin molding member is integrally formed with the base and the lead pairs. The first resin molding member defines a recessed portion at a mounting side surface on the base where a light emitting device is to be mounted. The recessed portion is formed to open upwardly and to have a side surface. The lead pairs are partially exposed at a bottom surface area of the recessed portion. The first lead or the second lead is capable of mounting a protection device thereon such that the protection device is covered by the first resin molding member. | 2011-05-12 |
20110111083 | USE OF XYLITOL FOR THE ECONOMIC IMPROVEMENT OF INTENSIVE PIG FARMING PRODUCTION - Use of xylitol for the economic improvement of intensive pig farming production, characterized by the presence of xylitol with a concentration of between 0.01% and 4% in the final feed. | 2011-05-12 |
20110111084 | Chewing Gum and Gum Base Comprising Styrene-Isoprene-Styrene Copolymers - A chewing gum includes at least one styrene-isoprene-styrene copolymer (SIS) in an amount from about 0.1% to about 70% by weight of the chewing gum. According to an advantageous embodiment, a chewing gum may be obtained which shows much improved features with regard to rheological properties, elastic properties and storage abilities. | 2011-05-12 |
20110111085 | METHODS AND SYSTEMS FOR PRODUCING ETHANOL USING RAW STARCH AND FRACTIONATION - The present invention relates to methods for producing high levels of alcohol during fermentation of plant material, and to the high alcohol beer produced. The method can include fractionating the plant material. The present invention also relates to methods for producing high protein distiller's dried grain from fermentation of plant material, and to the high protein distiller's dried grain produced. The method can include drying a co-product by ring drying, flash drying, or fluid bed drying. The present invention further relates to reduced stack emissions from drying distillation products from the production of ethanol. | 2011-05-12 |
20110111086 | Method of Improving Flavor Stability In Fermented Beverages - This invention provides novel methods for stabilizing the flavor of a fermented beverage, most particularly beer, by the addition of 3,4-hydroxytryosol prior to, or during early stages of, fermentation of the beverage. The invention is also directed to the fermented beverage prepared by such a method. | 2011-05-12 |
20110111087 | FOOD AND BEVERAGE SUPPLEMENT - Compositions obtained from vegetation water from olives as an additive and methods for using the compositions as an antibacterial and/or antioxidant are described. Included are olive-derived biophenol and hydroxytyrosol-rich compounds. | 2011-05-12 |
20110111088 | Method for producing dough pieces which can be stored for a long period of time - Method for the production of dough pieces suitable for long-term storage in which the dough pieces are placed in a climate-controlled room, a relatively humidity of 100% is established, whereby water is atomized at a droplet size <10 μm; and the temperature of the room is lowered and the lowered temperature is maintained until the core temperature of the dough piece is below the specific freezing point of the dough piece. | 2011-05-12 |
20110111089 | Aerated Gluten Polymeric Composition - The present invention relates to methods for producing an aerated polymeric composition or aerated polymeric pet chew and the resultant product. The aerated pet chew includes a dry blend, a leavening agent, and a plasticizing slurry. The dry blend includes an amount of protein polymer. | 2011-05-12 |
20110111090 | MICROBIOLOGICAL REPROCESSING OF BY-PRODUCTS OF BIODIESEL PRODUCTION - An industrial method of reprocessing a mixture of by-products produced during biodiesel production containing a glycerol fraction and degumming residue as well as a feed additive, which may be obtained by this method. | 2011-05-12 |
20110111091 | METHOD FOR PREPARING A LEAVEN FROM RAW MILK, LEAVEN OBTAINED BY MEANS OF THIS METHOD AND USE OF THIS LEAVEN FOR PRODUCING A MILK PRODUCT - A method, termed “bionative” method, for preparing a leaven, in which: a raw milk is selected from the group formed from raw milks of which the pH is capable of reaching, during a step of stabilising fermentation by acidifying lactic fermentation of the raw milk, at least one selection temperature, a value of 5.5 in more than 15 h, and a minimum value of 5.0 in less than 48 h, and then a raw milk-stabilising treatment is carried out. The treatment includes at least one step, termed stabilising fermentation step, of acidifying lactic fermentation of a fermentation medium, including a first stabilising fermentation step carried out using a fermentation medium including the raw milk, in which at least one stabilising fermentation step is interrupted when the pH of the fermentation medium reaches a value of between 4.9 and 6.0. | 2011-05-12 |