19th week of 2014 patent applcation highlights part 40 |
Patent application number | Title | Published |
20140127263 | AUGMENTATION OF TITER FOR VACCINATION IN ANIMALS - The disclosure relates to a composition added to animal feed used in combination with a vaccine to enhance the effectiveness of the vaccine. Amongst other effects, the composition raises the titer of antibodies to the vaccine. | 2014-05-08 |
20140127264 | INFECTIOUS BRONCHITIS VIRUS (IBV) SPIKE PROTEIN AS SUBUNIT VACCINE - The present invention relates to Infectious bronchitis virus (IBV) spike protein or a fragment thereof comprising a receptor-binding domain, wherein said spike protein or said fragment thereof is C-terminally fused to a trimerisation or tetramerisation domain. Such proteins form trimer or tetramer structures and as such they mimic the natural context of the spike protein. The present invention further relates to subunit vaccines comprising such a protein, to DNA molecules encoding such proteins, to plasmids comprising such DNA molecules, to avian live recombinant carrier viruses (LRCV's) comprising such DNA molecules or plasmids, to vaccines comprising such DNA molecules, plasmids and LRCV's and to combination vaccines comprising an IBV spike protein, DNA molecules, plasmids or LRCV's encoding such a protein, and another IBV vaccine capable of inducing protection against another IBV serotype and/or a vaccine capable of inducing protection against another avian pathogen. | 2014-05-08 |
20140127265 | GUINEA PIG CYTOMEGALOVIRUS (CIDMTR Strain) - The present disclosure provides an isolated or purified guinea pig cytomegalovirus (GPCMV) Strain CIDMTR, glycoproteins from GPCMV Strain CIDMTR, and methods of use thereof. | 2014-05-08 |
20140127266 | PLANT PRODUCED VACCINE FOR AMEBIASIS - Disclosed herein are methods of making a vaccine against | 2014-05-08 |
20140127267 | FUNGAL-DERIVED CARBOHYDRATE-CONJUGATED SCAFFOLD - The present invention provides for compositions and methods for a purified fungal carbohydrate-linked polymer bead platform, which can serve as an artificial fungus-like particle to measure specific patient immune responses to fungal carbohydrate antigens. A specific embodiment comprises a purified β-1,3-glucan chemically conjugated to a polymer bead. | 2014-05-08 |
20140127268 | Method for Expanding Monocytes - The invention relates to an ex vivo method for expanding monocytes, macrophages or dendritic cells, which method comprises inhibiting the expression or the activity of MafB and c-Maf in monocytes, macrophages or dendritic cells; and expanding the cells in the presence of at least one cytokine or an agonist of cytokine receptor signalling. | 2014-05-08 |
20140127269 | Anti-Inflammatory Peptide Derived From Thrombospondin-1 and Uses Thereof - The invention provides compositions and methods for utilizing a peptide of thrombospondin-1 as an anti-inflammatory agent. | 2014-05-08 |
20140127270 | Compositions and Methods for Preventing and Ameliorating Fouling on Medical Surfaces - A composition which can be detached from a surface which composition serves the purpose of impeding the detrimental effects of adherent fouling from the environment surrounding the surface. The composition may be single layered or multilayered as to allow for removal or attachment at multiple time points and/or over different durations. These time points may correspond to a progression to a negative effect of fouling, such as progression from biofilm maturation to bacterial detachment into host tissue for indwelling medical devices, or a predetermined threshold of tolerable fouling effect, such as blockage of a foley catheter by organic and inorganic encrustation material. This composition does not contribute to the function of the surface or the object whose boundaries are defined by the surface, such that its attachment or detachment is primarily aimed at mitigating the effects of fouling. | 2014-05-08 |
20140127271 | BLOCK COPOLYMERS FOR STABLE MICELLES - The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. Compositions herein are useful for drug-delivery applications. | 2014-05-08 |
20140127272 | NANOMETER-SIZED PRODRUGS OF NSAIDS - The present invention describes nanoprodrugs of non-steroidal anti-inflammatory drug (NSAIDs) and nanoprodrugs of α-lipoic acid-containing and NSAIDs. These nanoprodrugs have antioxidant properties and stimuli-responsiveness, which can be used to treat various disease conditions. | 2014-05-08 |
20140127273 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES - Disclosure is provided for imidazole derivative compounds that prevent, remove and/or inhibit the formation of biofilms, compositions comprising these compounds, devices comprising these compounds, and methods of using the same. | 2014-05-08 |
20140127274 | COMPOSITION COMPRISING PERLITE AND A POLYMER BEARING A CARBOSILOXANE DENDRIMER-BASED UNIT - The present invention concerns a composition comprising a physiologically acceptable medium containing perlite and at least one vinyl polymer bearing at least one carbosiloxane dendrimer-based unit. The composition is used in the care of and for making up the skin, in particular to provide a matt effect. | 2014-05-08 |
20140127275 | Composition Containing a Cellulose Derived Capsule With A Sunscreen - A sunscreen composition comprised of one or more sunscreen active agents encapsulated in a cellulose derived capsule wherein the composition can contain one or more additional agents. A sunscreen composition can be mixed with a bodywash, shampoo, conditioner, lotion, gel, soap, cream, hand sanitizer, spray or mousse and can be used by an individual during their normal hygiene processes, such as during a shower or bath or while applying a body product to their skin or hair. | 2014-05-08 |
20140127276 | Methods for Reducing Airborne Bacteria and Mycetes and Apparatus for the Same - A method for removing airborne bacteria and airborne mycetes from indoor air comprises imparting microbiocidal and microbiostatic properties to fabric by treating the fabric with one or more naturally occurring biocides, positioning the treated fabric in a sheet-like orientation, and blowing indoor air through the fabric. | 2014-05-08 |
20140127277 | METHOD OF PREPARING COATING FILM CONTAINING NITROGEN MONOXIDE ON SURFACE OF MATERIAL USING CATECHOLAMINE - A method of coating surfaces of various body-implantable materials with control-releasable nitrogen monoxide using a catecholamine, more particularly, technology of preparing a coating film containing a diazeniumdiolate functional group on a surface of a material to be coated using a catecholamine, is provided. The coating film prepared by the method has advantages in that nitrogen monoxide can be stably supplied under an in vivo environment, and can be suitably used in a living body without causing cytotoxicity. Therefore, among the materials having a coating film formed on a surface thereof, the body-implantable material is especially expected to be widely used for medical and health applications including treatment of ischemic disorders such as arteriosclerosis through controlled release of nitrogen monoxide, regulation of penile erections, antibacterial and antiviral effects, and wound healing. | 2014-05-08 |
20140127278 | Method Of Treating Vascular Disease In Diabetic Patients - The present invention relates to the treatment of vascular disease in a diabetic patient using a drug-eluting implantable medical device that releases everolimus from three distinctly loaded drug reservoir layers wherein at least one of the layers comprises at least 200 μg/cm | 2014-05-08 |
20140127279 | Implantable Device Having a Slow Dissolving Polymer - The present invention provides an implantable device having a coating including a slow dissolving polymer or material and the methods of making and using the same. | 2014-05-08 |
20140127280 | INTRAUTERINE DELIVERY SYSTEM FOR CONTRACEPTION - The invention relates to a method for contraception and for reducing menstrual problems and inducing amenorrhea, wherein an intrauterine delivery device is used for the controlled release of a combination of progestogen or a drug having a progestogenic activity and at least one therapeutically active substance capable of preventing or suppressing abnormal and/or irregular endometrial bleeding over a prolonged period of time. | 2014-05-08 |
20140127281 | PROPYNYLAMINOINDAN TRANSDERMAL COMPOSITIONS - Propynylaminoindan (e.g., Rasagiline) transdermal compositions are provided. Aspects of the transdermal compositions include a matrix which includes the propynylaminoindan, a pressure sensitive adhesive that includes an acrylate copolymer and a cationic acrylic copolymer. Also provided are methods of using the transdermal compositions and kits containing the transdermal compositions. | 2014-05-08 |
20140127282 | Membrane - The invention relates to a membrane for supporting cells, especially retinal pigmented epithelial (RPE) cells. The membrane is useful in the treatment of conditions such as age related macular degeneration. The membrane may also be used to support retinal pigmented epithelial cell precursors and retinal cell derivative cells formed from the differentiation of RPE on the membrane. | 2014-05-08 |
20140127283 | COMPOSITIONS COMPRISING HONEY AND A SUPER- ABSORBENT MATERIAL - A composition comprising honey and a super-absorbent material. A method of treating a lesion comprising applying a composition comprising honey and a super-absorbent material to the lesion. A method of manufacturing the composition of the invention, comprising: (a) providing at least one type of honey; (b) providing at least one super-absorbent material; and (c) combining the honey and super-absorbent material. | 2014-05-08 |
20140127284 | MICRO-RNAS AND MICRO-RNA INHIBITORS TO MODULATE BLOOD VESSEL GROWTH, PATTERNING, TUMOR GROWTH AND MALIGNANT DISEASE AND METHOD FOR MAKING AND USING THEM - In alternative embodiments, the invention provides compositions and methods comprising use of microRNAs and microRNA inhibitors to modulate blood vessel growth (angiogenesis), e.g., act as anti-angiogenic agents, and modulate cell and tumor microenvironment patterning, cancer cell and tumor growth and malignant disease (metastasis). In alternative embodiments, the invention provides compositions and methods that can sensitize blood vessels, e.g., tumor blood vessels, to radiation and agents and chemotherapies that cause DNA damage. | 2014-05-08 |
20140127285 | Composition and Method for Making Oligo-Benzamide Compounds - The present invention includes compound compositions and methods of making compounds that include an oligo-benzamide compound having at least two optionally substituted benzamides. | 2014-05-08 |
20140127286 | COSMETIC COMPOSITION FOR USE IN INCREASING THE COLLAGEN SYNTHESIS IN SKIN CELLS - The invention refers to a cosmetic composition for increasing collagen synthesis in skin cells comprising 0.001-0.5 wt % of a Phaeodactylum tricornutum extract, 0.00001-2.0 wt % of Dimer Tripeptide-43 or Hydrolyzed Rice Protein, and cosmetic auxiliaries. The cosmetic composition comprising the combination of both components has an synergistic effect on collagen I synthesis in skin cells and has a booster effect to other substances which are known to have an enhancing effect to collagen I synthesis. | 2014-05-08 |
20140127287 | LIPOSOME-ENCAPSULATED HYDROGELS FOR USE IN A DRUG DELIVERY SYSTEM - Drug delivery systems including a lipogel are disclosed. The lipogels allow for high drug loading and sustained release of drug molecules. Also disclosed are methods of making the drug delivery systems including lipogels. | 2014-05-08 |
20140127288 | LIPOSOME CONTAINING PYRROLOQUINOLINE QUINONE AND SUGAR - An object of the present invention is to provide a composition that enables extension of the concentration range in which pyrroloquinoline quinone exerts cell growth-promoting function, and an efficient method of producing the composition. According to the present invention, there is provided a liposome composition comprising liposomes individually containing pyrroloquinoline quinone or a salt thereof and sugar, 50% or more of the liposomes having a particle diameter in the range of from 1 to 10 μm, and a method of producing the composition. | 2014-05-08 |
20140127289 | LOW ERUCTATION COMPOSITION AND METHODS FOR TREATING AND/OR PREVENTING CARDIOVASCULAR DISEASE IN A SUBJECT WITH FISH ALLERGY/HYPERSENSITIVITY - In various embodiments, the present invention provides pharmaceutical compositions comprising fatty acids and methods for treating subjects using same. | 2014-05-08 |
20140127290 | Microcapsules Encapsulating Living Cells - Disclosed are devices and methods for encapsulating living cells, microencapsulated cells produced by the disclosed devices and methods, as well as methods of using the disclosed microencapsulated cells. | 2014-05-08 |
20140127291 | EXTENDED RELEASE ACETAMINOPHEN LIQUID PHARMACEUTICAL COMPOSITIONS - Disclosed herein is an extended release liquid pharmaceutical composition comprising extended release particles dispersed in a liquid medium. The extended release particles comprise acetaminophen dispersed or encapsulated in a water insoluble polymer and/or wax to provide an extended release dosage form of acetaminophen. The liquid medium comprises water, an active pharmaceutical ingredient in immediate release form and, optionally, excipients. The composition is storage stable for at least 6 months at 40° C. and 75% relative humidity. | 2014-05-08 |
20140127292 | PHARMACEUTICAL COMPOSITIONS FOR THE ORAL ADMINISTRATION OF HEPARIN OR DERIVATIVES THEREOF - Oral pharmaceutical compositions for the controlled release of heparin or derivatives thereof, for example dalteparin, salts and/or derivatives thereof, comprising (a) a matrix consisting of amphiphilic compounds and lipophilic compounds with melting point lower than 90° C. in which the active ingredient is at least partially dispersed; (b) an outer hydrophilic matrix in which the lipophilic/amphiphilic matrix is dispersed; (c) optionally, other excipients suitable for solid pharmaceutical forms. The treatment of inflammatory bowel diseases (IBD) by administering to a patient in need thereof an effective amount of dalteparin, salts and/or derivatives thereof is also disclosed. | 2014-05-08 |
20140127293 | Calcium Carbonate Granulation - Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet sizes upon compression than previously available. | 2014-05-08 |
20140127294 | ORAL SOLID FORMULATION OF COMPOUND ANTI-TUBERCULAR DRUG AND PREPARATION METHOD THEREOF - Provided is an oral solid preparation of a compound anti-tubercular drug, wherein the active ingredients are rifampicin, isoniazid, pyrazinamide and ethambutol hydrochloride. The compound oral solid preparation is a coated tablet with coated core or a coated three-layer tablet, wherein the two active ingredients rifampicin and isoniazid do not contact directly. The compound oral solid preparation not only improves the stability of the compound preparation, but also improves the bioavailability of rifampicin. | 2014-05-08 |
20140127295 | COMPOSITIONS, PROCESS OF PREPARATION OF SAID COMPOSITIONS AND METHOD OF TREATING INFLAMMATORY DISEASES - The present disclosure describes a composition and a kit having a plurality of compounds for use in the treatment of inflammatory joint diseases and chronic inflammatory connective tissue diseases, such as Rheumatoid Arthritis (RA). The disclosure also relates to a process of obtaining the composition and the method of treating diseases by administration of the compositions. | 2014-05-08 |
20140127296 | Pharmaceutical preparation and method for treatment of diabetes - A pharmaceutical composition for use in oral medication for the treatment of diabetes mellitus can include an antacid agent with an enteric coating, which permits the antacid agent to be delivered in the small intestines where it reduces acidity thereby causing a lowering of blood sugar levels. The pharmaceutical composition can be packaged in various tablet forms, including standard tablets and multiple pellet tablets. The pharmaceutical composition can further include an enteric coated gastric acid secretion inhibitor. Also disclosed is a method for the treatment of diabetes mellitus. | 2014-05-08 |
20140127297 | NUTRACEUTICAL COMPOSITION FOR LIMITING THE ABSORPTION OF DIETARY LIPIDS AND FOR INDUCING WEIGHT LOSS, COMPRISING, AS ACTIVE AGENT, AT LEAST ONE EXTRACT OF CARROT - The invention relates to a nutraceutical composition for limiting the absorption of dietary lipids and for inducing weight loss in a human or animal mammal, characterized in that it comprises as active agent at least one extract of carrot, at least half of which is fibres. | 2014-05-08 |
20140127298 | MUCOSOMAL ALLERGEN-SPECIFIC IMMUNOTHERAPY WITH INITIAL DOSING AFTER START OF POLLEN SEASON - The present invention relates to mucosal allergen-specific immunotherapy with a seasonal allergen, wherein the therapy is initiated after start of the pollen season of the seasonal allergen. Preferably, the seasonal allergen is provided in solid dosage form and is administered daily. Furthermore, advantageously, the same dose may be used throughout the treatment period since up-dosing is not required. | 2014-05-08 |
20140127299 | GRAS Enteric Coating Formulations and Methods of Making and Using Same - Disclosed herein are food-grade enteric coating compositions designed to release pharmaceutical and/or nutraceutical products at various regions of the intestines, wherein said compositions comprise a film former and a pore former. Also disclosed herein are methods of making and using same. | 2014-05-08 |
20140127301 | Adjuvant Incorporation in Immunonanotherapeutics - The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface and an immunostimulatory moiety. In some embodiments, the immunostimulatory moiety is adjuvant. The invention provides pharmaceutical compositions comprising inventive nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive nanocarriers and pharmaceutical compositions thereof. | 2014-05-08 |
20140127302 | Analgesic Pharmaceutical Composition For Oral Administration - The disclosed analgesic pharmaceutical composition for oral administration is characterised in that it contains an opioid and a pharmaceutically admissible magnesium (II) compound, possibly along with one or more pharmaceutically admissible ancillary substances. | 2014-05-08 |
20140127303 | SUSTAINED-RELEASE COMPOSITION CONTAINING PEPTIDES AS ACTIVE INGREDIENT - The present invention relates to a sustained-release drug composition consisting essentially of microparticles of a peptide as the active substance and a biocompatible water-soluble polymer, in particular peptide as meianocortin receptor ligand. The present invention relates also to an injection formulation comprising the sustained-release drug composition suspended in an injection medium. | 2014-05-08 |
20140127305 | MULTIFUNCTIONAL NANOPARTICLE DESIGNS AND APPLICATIONS - Methods, structures, devices and systems are disclosed for fabricating and implementing nanoparticles with hollow core and sealable holes. In one aspect, a nanoparticle device can includes a shell structure including at least two layers including an internal layer and an external layer, the internal layer structured to enclose a hollow interior region and include one or more holes penetrating the internal layer, the external layer is of a porous material and formed around the internal layer and sealing the one or more holes, and a substance contained within the hollow interior region, the substance incapable of passing through the external layer. | 2014-05-08 |
20140127306 | Modified Release Formulations Containing Drug-Ion Exchange Resin Complexes - An aqueous liquid suspension containing a coated drug-ion exchange resin complex comprising a core composed of an amphetamine complexed with a pharmaceutically acceptable ion-exchange resin and an uncoated amphetamine-ion exchange resin complex is provided. The coated amphetamine-ion exchange resin complex is in admixture with a polymer to form a matrix. Methods of making the coated complex and the liquid suspension are described. | 2014-05-08 |
20140127307 | MICROPELLET COMPOSITIONS COMPRISING PANCREATIN CONTAINING DIGESTIVE ENZYME MIXTURE - The present invention relates to a small particle size composition comprising pancreatin containing digestive enzymes for use in patients in need, including pediatric, geriatric, and adult patients, particularly those patients with dysphagia or wherein enteral administration using such composition would be suitable. In addition, the invention is directed to the composition as particles, such as micropellets or microgranules having a high potency, high useable yield and at least 10%-90% of 400-800 μm. Furthermore, the composition optionally has an improved enteric coating and concomitant improved stability and enzyme activity compared to conventional prepared enterically coated pancreatic enzyme particles. | 2014-05-08 |
20140127308 | ENCAPSULATED CELLS FOR HORMONE REPLACEMENT THERAPY - A composition comprising microcapsules, the microcapsules containing both live mammalian ovarian granulosa cells and live mammalian ovarian theca cells, is described. In some embodiments, the granulosa cells and the theca cells are contained in separate microcapsules in the composition; in some embodiments, the granulosa cells and the theca cells are contained together in the same microcapsules in the composition The composition is can be used for estrogen, and optionally also progesterone, delivery, and hence is preferably free or essentially free of oocytes. Methods of using the same and pharmaceutical formulations containing the same are also described. | 2014-05-08 |
20140127309 | ENCAPSULATED POLAR MATERIALS AND METHODS OF PREPARATION - The present invention meets one or more of the above needs and is a composition comprising plurality of capsules wherein the capsules comprise: a core of one or more highly polar liquids; one or more polar active materials dissolved in or dispersed in one or more highly polar liquids; a mixture of one or more polymers and one of more highly polar liquids; or a mixture of one or more polymers, one or more highly polar liquids and one or more polar active materials, and a shell comprising, particles in a polymer matrix or particles; wherein the thickness of the shell is sufficient to prevent passage of the highly polar liquid or the active material through the shell or to control the rate passage of the highly polar liquid or the active material through the shell with the proviso that the one or more polymers may be located in the core, in the polymer matrix of the shell or both. | 2014-05-08 |
20140127310 | TREATMENT OF DISEASE WITH POLY-N-ACETYLGLUCOSAMINE NANOFIBERS - This application relates to compositions comprising shortened fibers of poly-N-acetylglucosamine and/or a derivative thereof (“sNAG nanofibers”) and the use of such compositions in the treatment of disease. | 2014-05-08 |
20140127311 | BIO-COMPATIBLE NANO-POLYMER PARTICLES COMPRISING ACTIVE INGREDIENTS FOR PULMONARY APPLICATION - The present invention provides biocompatible nano-polymer particles which are composed of a biocompatible polymer, a stabilizer and an active agent for the treatment of pulmonary hypertension or erectile dysfunction and which can be used to produce a pharmaceutical preparation for the treatment of pulmonary hypertension or erectile dysfunction. Biocompatible nano-polymer particles of this invention have a diameter ranging from 10 nm to 10 μm auf, a stabilizing layer thickness between 0 and 50 nm, contain between 0 and 50% of an active agent for the treatment of pulmonary hypertension or erectile dysfunction, are nebulizable and continuously release the active agent over a period of up to 48 hours. Biocompatible nano-polymer particles of this invention can be synthesized for example using the emulsion technique known to the expert with subsequent solvent evaporation or via spray drying. | 2014-05-08 |
20140127312 | POLYMERS FOR REVERSING HEPARIN-BASED ANTICOAGULATION - Embodiments presented herein relate to various polymers. Some of the polymer embodiments are heparin binding polymers. Some embodiments of the heparin binding polymers can be employed to bind to heparin for methods such as separating, purifying, removing, and/or isolating heparin and heparin like molecules. | 2014-05-08 |
20140127313 | PREVENTION AND TREATMENT OF HIV INFECTION - A pharmaceutical composition for preventing and treating HIV infection includes an active ingredient made by a process involving a series of intra- and inter-species blood transfers made among male and female animals. The process modifies the components of blood in the animals such that the blood from the last animal in the series of transfers can be used as the active ingredient in a pharmaceutical composition which, when administered to an HIV-infected human subject, can eliminate any detectable HIV in the subject. | 2014-05-08 |
20140127314 | COMPOSITIONS, USES, AND PREPARATION OF PLATELET LYSATES - In certain embodiments, this disclosure describes compositions comprising platelet lysates depleted of fibrinogen. In a further embodiment, the composition further comprises a cell culture medium component. This disclosure also provides a method for preparing the composition, comprising the steps of (a) lysing platelets providing a lysate; (b) removing cell debris; and (c) depleting fibrinogen by forming a removable mass by adding a metal salt such as calcium chloride. Furthermore, the disclosure also describes the product produced using said method. | 2014-05-08 |
20140127315 | Caudal Salve - A caudal salve is a topical treatment for irritated skin around a user's posterior. The caudal salve includes a plurality of ingredients that each has their own unique beneficial properties. The plurality of ingredients includes a quantity of bees wax, a quantity of shea butter, a quantity of coconut oil, a quantity of yarrow-plant oil, a quantity of calendula-flower oil, a quantity of menthol, and a quantity of peppermint oil. The bees wax, the shea butter, and the coconut oil are typically used as the base materials for the caudal salve. The yarrow-plant oil, the calendula-flower oil, the menthol, and the peppermint oil are typically used as the supplemental yet active materials for the caudal salve. | 2014-05-08 |
20140127316 | PROPOLIS AND CAFFEIC ACID PHENETHYL ESTER AND USES THEREOF - Methods for treating a subject with cancer using a combined therapeutic regimen comprising administering propolis or caffeic acid phenethyl ester (CAPE) in conjunction with other cancer therapeutics are described herein. More particularly, methods for treating subjects with breast cancer using the combined therapeutic regimen are embodied herein. The present methods are particularly useful for treating cancer patients (e.g., breast cancer patients) who are refractory to or who have become refractory to the cancer therapeutic/s used in combination with propolis or CAPE. Propolis or CAPE for use in a combined treatment with other cancer therapeutics for treating cancer patients and compositions comprising propolis or CAPE and other cancer therapeutics are also encompassed herein wherein the ability of propolis or CAPE to act as a histone deacetylase (HDAC) inhibitor is used to advantage. Also encompassed herein are methods and compositions for the treatment of diseases caused by or associated with viral infections. In particular embodiments, methods and compositions for the treatment of viral infections caused by or associated with retroviruses are envisioned, wherein the ability of propolis or CAPE to act as a histone deacetylase (HDAC) inhibitor is also used to advantage. Also encompassed herein are methods and compositions for the treatment of diseases caused by or associated with viral infections. | 2014-05-08 |
20140127317 | Methods of Manufacture of Immunocompatible Amniotic Membrane Products - Provided herein is a placental product comprising an immunocompatible amniotic membrane. Such placental products can be cryopreserved and contain viable therapeutic cells after thawing. The placental product of the present invention is useful in treating a patient with a tissue injury (e.g. wound or burn) by applying the placental product to the injury. Similar application is useful with ligament and tendon repair and for engraftment procedures such as bone engraftment. | 2014-05-08 |
20140127318 | BACTERIAL AND FUNGICIDAL COMPOSITION FOR PLANTS AND CROPS - Compositions comprising an effective amount of (1) hydrogen peroxide, an organic peroxide or a combination thereof; and (2) phosphorous acid, mono- and/or di-salts of phosphorous acid or a combination thereof are effective in preventing or controlling diseases in plants caused by pathogens. The disclosed compositions can be used by contacting a plant with an effective amount of such compositions. | 2014-05-08 |
20140127319 | SYNERGISTIC ANTIMICROBIAL PREPARATIONS CONTAINING CHLORITE AND HYDROGEN PEROXIDE - An anti-microbial preservative for use in ophthalmic and dermatologic products. The preservative includes from about 0.005 wt. % to about 0.20 wt. % chlorite compound and from about 0.005 wt. % to about 0.05 wt. % peroxy compound. Additionally, the preservative does not generate chlorine dioxide within the pH range of 5.0-8.8. Also included are an antimicrobial ophthalmic and dermatologic compositions for direct application onto an eye or skin of a living being including from about 0.005 wt. % to about 0.20 wt. % chlorite compound and from about 0.005 wt. % to about 0.05 wt. % peroxy compound. Also included are methods for treating dryness of the eyes and skin disorders (e.g., wounds, burns, infections, ulcerations, psoriasis, etc.) and for disinfecting and cleansing contact lenses while in place upon an eye by applying the composition to the eye or to the contact lens. | 2014-05-08 |
20140127320 | DELIVERY OF BIOLOGICALLY-ACTIVE AGENTS USING VOLATILE, HYDROPHOBIC SOLVENTS - A composition and method adapted for delivery of hydrophilic, biologically-active agents are disclosed. The composition can include a reverse microemulsion formed from at least one hydrophilic, biologically-active agent solubilized by a hydrophobic reverse emulsion surfactant in a non-stinging, volatile, hydrophobic solvent. The non-stinging, volatile, hydrophobic solvent is selected from the group consisting of volatile linear and cyclic siloxanes, volatile linear, branched, and cyclic alkanes, volatile fluorocarbons and chlorofluorocarbons, liquid carbon dioxide under pressure, and combinations thereof. The reverse microemulsion can be an optically clear solution. | 2014-05-08 |
20140127321 | ANTIVIRAL RESIN MEMBER - To provide an antiviral resin member which can efficiently inactivate viruses and has excellent sustainability. | 2014-05-08 |
20140127322 | SOLID FORMS OF AN AZOCYCLIC AMIDE - Disclosed are solid forms of 1-[4-[4-[5-(2,6-difluorophenyl)-4,5-dihydro-3-isoxazolyl]-2-thiazolyl]-1-piperidinyl]-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]ethanone (Compound 1). Methods for the preparation of solid forms of Compound 1 and for the conversion of one solid form of Compound 1 into another are disclosed. | 2014-05-08 |
20140127323 | DIETETIC MULTI-COMPONENT SYSTEM - An improved multi-component system containing a main component and at least one additional component that is physically separated from the main component, and a use of the system as a food supplement and a pharmaceutical product. | 2014-05-08 |
20140127324 | METHODS AND COMPOSITIONS FOR REDUCING SHIGA TOXIN INDUCED TOXICITY IN MAMMALS - Manganese compositions effective in reducing Shiga toxin-induced toxicity in mammals infected with Shiga toxin-producing bacteria such as | 2014-05-08 |
20140127325 | Compositions and Method for Inhibiting Hepcidin Antimicrobial Peptide (HAMP) or HAMP-Related Gene Expression - The invention relates to lipid formulated double-stranded ribonucleic acid (dsRNA) targeting a hepcidin antimicrobial peptide (HAMP) and/or HAMP-related gene, and methods of using the dsRNA to inhibit expression of HAMP and/or HAMP-related genes. | 2014-05-08 |
20140127326 | Detection of Cancer by Volatile Organic Compounds From Breath - Provided are methods for detecting a cancer, such as an ovarian cancer. In certain aspects, the methods involve detecting or measuring one or more volatile organic compounds (VOCs) from the breath of a subject. Apparatuses for the collection of VOCs are provided. | 2014-05-08 |
20140127327 | PRESERVED TOPICAL FORMULATIONS WITH IMPROVED ANTIMICROBIAL ACTIVITY - A preservative consisting of a stabilized oxychloro complex and a polyol having from 3 to 6 carbons is disclosed herein. A composition comprising a stabilized chlorine dioxide. and a polyol having from 3 to 6 carbons is also disclosed herein. | 2014-05-08 |
20140127328 | METHODS AND COMPOSITIONS FOR TREATING ANXIETY DISORDERS OR SYMPTOMS THEREOF - The present invention relates to methods and compositions for reducing distress dysfunction, including emotional and physical distress. The invention entails co-administration of at least one Receptor Switcher and at least one Endorphin Enhancer. Additionally, at least one Synergistic Enhance and/or at least one Exogenous Opioid are also administered to enhance or prolong the therapeutic effects. | 2014-05-08 |
20140127329 | USE OF NITRITES FOR THE TREATMENT OF CEREBRAL AMYLOID ANGIOPATHY, AGE ASSOCIATED DEMENTIA, AND COGNITIVE DECLINE - The present invention relates to the medical use of nitrites, such as inorganic nitrites, or any pharmaceutically acceptable salts, solvates, compositions, or prodrugs thereof, in the treatment of conditions that benefit from increased cerebral vascular flow. The pharmaceutical compositions used in these methods, which can be formulated for oral administration, can provide immediate release or extended release of the nitrite ion (NO | 2014-05-08 |
20140127330 | METHOD OF MIXING GASES INCLUDING NITRIC OXIDE - A method of delivering nitric oxide can include mixing a first gas including oxygen and a second gas including a nitric oxide-releasing agent within a receptacle to form a gas mixture, where the receptacle includes an inlet, an outlet and a reducing agent, contacting the nitric oxide-releasing agent in the gas mixture with the reducing agent to generate nitric oxide, and delivering the gas mixture including nitric oxide from the receptacle to a mammal. | 2014-05-08 |
20140127331 | METHOD FOR PRODUCING BLACK GINSENG HAVING INCREASED GINSENOSIDE RH2 COMPONENT CONTENT, AND BLACK GINSENG PRODUCT PRODUCED BY MEANS OF THE PRODUCTION METHOD - The method for producing black ginseng having increased ginsenoside Rh2 component content of the present invention comprises the steps of: (a) washing ginseng and drying same under predetermined time conditions in a shaded place; and (b) repeatedly carrying out a plurality of times a process in which the dried ginseng is steamed under predetermined temperature and time conditions and is dried under conditions that differ from the temperature and time conditions during the steaming. By producing black ginseng via a plurality of steps under fixed conditions in this way, it is possible to increase the content of ginsenoside Rh2 as compared with hitherto. | 2014-05-08 |
20140127332 | EXTRACTS - Novel compositions which are useful in the treatment of mammals for the reduction of inflammation, especially in the gut, and which comprise an aqueous extract of an agricultural product. Preferred compositions comprise an aqueous extract of olive, or an aqueous extract of ginger. The compositions can optionally contain an aqueous extract of chamomile and/or an aqueous extract of artichoke and/or an aqueous extract of cinnamon. | 2014-05-08 |
20140127333 | Preparation, process and a regenerative method and technique for prevention, treatment and glycemic control of diabetes mellitus - A medicinal preparation, a process, a nutritional composition and regenerative and insulin potentiating method for humans and also for mammals for prevention, treatment and management/glycemic control, of diabetes mellitus by obtaining optimum glucose level in blood, by administering an extract of | 2014-05-08 |
20140127334 | DRUG COMPOUND FOR THE CONTROL OF BLOOD GLUCOSE, BLOOD LIPIDS AND WEIGHT - This invention provides compound health food compound containing licorice extract, which is made by alcohol-soluble and water-insoluble | 2014-05-08 |
20140127335 | FRAGRANCE PRIMER - A fragrance primer composition may include an astringent, a humectant, a film former, a solvent, a vitamin and at least three botanical products. The components may be ethyl alcohol, butylene glycol, acrylates/acrylamide copolymer, water, tocopheryl acetate, cucumis sativus fruit extract, chamomilla recutita flower/leaf extract, and aloe barbadensis leaf juice respectively. The fragrance primer composition may be applied as a surface barrier to a user's skin from a fragrance, perfume, and/or cologne. | 2014-05-08 |
20140127336 | Process for the Preparation of a Pharmaceutically Effective Extract from Arthrospira Spec. - A process for the preparation of a pharmaceutically effective extract from the cyanobacterium | 2014-05-08 |
20140127337 | Apparatuses for Making Cathodes for High-temperature, Rechargeable Batteries - The approaches and apparatuses for fabricating cathodes can be adapted to improve control over cathode composition and to better accommodate batteries of any shape and their assembly. For example, a first solid having an alkali metal halide, a second solid having a transition metal, and a third solid having an alkali metal aluminum halide are combined into a mixture. The mixture can be heated in a vacuum to a temperature that is greater than or equal to the melting point of the third solid. When the third solid is substantially molten liquid, the mixture is compressed into a desired cathode shape and then cooled to solidify the mixture in the desired cathode shape. | 2014-05-08 |
20140127338 | Injection Mold With Fail Safe Pressure Mechanism - A low pressure injection mold includes a failsafe pressure mechanism that prevents the low pressure injection mold from being subjected to excessive injection pressures or excessive clamping tonnage that could damage the low pressure injection mold. | 2014-05-08 |
20140127339 | Device and Method for a Layerwise Mfg. of a 3-Dimensional Object From a Building Material in Powder Form - A method is provided, by which a three-dimensional object is manufactured by a subsequent solidification of layers of a building material in powder form at the positions in the respective layer that corresponds to the cross-section of the object by means of the action of a laser or another energy source, | 2014-05-08 |
20140127340 | PUNCH ARRANGEMENT FOR A PRESS AND PRESS - Punch arrangement for a press, in particular a rotary press, comprising at least one press punch having a punch head, a tool region and a punch shank extending between the punch head and tool region, further comprising at least one punch guide having at least one guide bore in which the punch shank of the at least one press punch is guided in an axially movable manner and at least one variable length sealing sleeve at least partially surrounding the shank, which sealing sleeve is retained with its first end against the punch shank or against the tool region of the press punch, the sealing sleeve being retained with its second end against an inner wall of the guide bore, the second end of the sealing sleeve, with the punch shank located in the guide bore, being captured between the inner wall of the guide bore and the punch shank. The invention further relates to a press and a rotary press. | 2014-05-08 |
20140127341 | Pellet Press with a Cutting-to-Length Device for Biogenic Fibrous Pellets - The invention refers to a cutting-to-length device ( | 2014-05-08 |
20140127342 | Beltless pretzel dough rolling machine - This invention relates to an apparatus for forming strands or rods of dough from a random but generally spherical shaped quantity of dough. The apparatus is comprised of three rigid co-rotating rollers, two of which are static, and the third roller which is movable, which gradually reduces the space allowed for the rotating dough to reside. The dough bolus is formed into a dough strand wherein all the rollers are still rotating. Retraction of the movable roller will allow for the newly formed strand of dough to exit the apparatus. The strand of dough is then ready for twisting into a pretzel shape. The newly twisted pretzel dough is then glazed, salted and then baked to produce a finished pretzel. | 2014-05-08 |
20140127343 | EXTRUDER FEED THROAT HAVING HARDENED TILES ON INTERNAL SURFACES - A feed throat for an extruder device includes a body having an inlet defined by a longitudinal opening along a side of the body and an outlet positioned at an end of the body. The body has a substantially cylindrical interior surface which has a plurality of raised surfaces which extend radially inward from and longitudinally along the interior surface. One or more hardened tiles are secured to one or more of the raised surfaces. | 2014-05-08 |
20140127344 | CONFECTIONERY PROCESSING MACHINE AND MANUFACTURING PROCESS - A confectionery processing machine has a hopper attached to a dispensing unit. The dispensing unit comprises a plurality of co-operating piston and nozzles. The hopper is arranged to supply an edible material to the plurality of co-operating piston and nozzles. The dispensing unit is arranged in order to dispense the edible material from the plurality of co-operating piston and nozzles. The confectionery processing machine is improved by providing the hopper with at least two separate compartments. Here, each compartment separately provides edible material to a portion of the plurality of pistons. Consequently, a more flexible confectionery processing machine is provided because all the plurality of piston and nozzles are not provided from the same compartment. | 2014-05-08 |
20140127345 | BUILDING MOLD WITH COPPER NONWOVEN - A building mold for producing shaped composite materials contains at least one first surface section, which is provided for shaping the composite material, and a second surface section, which is located substantially opposite the first section and is not provided for shaping the composite material. A heating device is arranged between the two sections. At least one planar metal structure, which is in thermal contact with the first surface section, is arranged between the first surface section and the second surface section or is on the first surface section and is configured to distribute the heat given off by the heating device in a planar manner. | 2014-05-08 |
20140127346 | System for Manufacturing Core of Vacuum Insulation Panel - Provided herein is a system for manufacturing a core of a vacuum insulation panel, the system comprising: a plurality of molding cast parts disposed along one direction, and providing a molding space for core material to be supplied and press-molded; a plurality of raw material suppliers distanced from one another, and supplying core material to the molding space; a press-molder disposed between the raw material suppliers, and receiving the molding cast part where the core material is supplied through the raw material supplier, and pressing the molding space; and a carrier transferring the molding cast part after the core material is supplied by the raw material supplier and the molding space is press-molded by the press-molder. | 2014-05-08 |
20140127347 | INJECTION MOLD DEVICE AND INJECTION MOLDING MACHINE - A first fitting surface | 2014-05-08 |
20140127348 | Selective Positioning of Nozzle Tip Relative to Mold-Side of Runner System - The inventors have researched a problem associated with known molding systems that inadvertently manufacture bad-quality molded articles or parts. After much study, the inventors believe they have arrived at an understanding of the problem and its solution, which are stated below, and the inventors believe this understanding is not known to the public. During operation, the gate orifice and nozzle tip position are fixed. The inventors believe that there appears to be no known mechanism that allows optimization of the tip to gate relationship. Known methods of adjusting position of a nozzle tip, such as shimming between a cavity plate and a manifold plate, or replacing nozzle stack components, may be time consuming and difficult. The known hot runner assembly often must be removed from the molding machine to make the desired adjustments. | 2014-05-08 |
20140127349 | VEGETABLE OIL COMPOSITION CONTAINING PALM MID-FRACTION FAT AND METHOD OF REDUCING PLASMA CHOLESTEROL - A method and composition for reducing the cholesterolemic effect in mammals of ingesting a blended nutritional fat composition containing a palm mid-fraction (PMF) hardstock fat combined with an unsaturated vegetable oil. The composition is solid or semi-solid at 20° C. and fluid at 35° C., and includes between 15% and 45% by weight linoleic acid. The weight ratio of disaturated triglyceride (DST) molecules to trisaturated triglyceride (TST) molecules is greater than 10:1, and the PMF hardstock fat contains approximately 50% to 95% by weight DST molecules, the majority of which contain either palmitic acid or a combination of palmitic and stearic acids at the sn-1 and sn-3 triglyceride positions and either oleic acid or linoleic acid at the sn-2 molecular position. | 2014-05-08 |
20140127350 | METHOD AND COMPOSITION FOR ENHANCING MILK PRODUCTION AND MILK COMPONENT CONCENTRATIONS - A method of feeding a ruminant that entails providing a feed that comprises sugar alcohol and at least one additional feed component, where the feed is free of rumen-protected fatty acid or comprises less than 10 weight percent rumen-protected fatty acid, based on the total weight of the feed and further entails orally supplying the feed to the ruminant during a pre-partum period when the ruminant is pregnant, where the ruminant ingests the feed and sugar alcohol during the pre-partum period. | 2014-05-08 |
20140127351 | NUTRITIONAL SUPPLEMENTS INCLUDING MEAL REPLACEMENTS AND RELATED METHODS - A nutritional or dietary supplement composition useful for formulating meal replacements, particularly beverage-based meal replacements. The composition is absorbed well in patients with compromised gastrointestinal absorption status, such as those having undergone bariatric surgery, other gastrointestinal surgery, those undergoing chemotherapy, and those with other gastrointestinal absorption disorders. Moreover, the compositions are nutritious foods for healthy people. Lastly, the compositions are useful for people with insulin disorders, difficulty maintaining healthy body weight, or inflammation-related disorders. Related methods are also provided. | 2014-05-08 |
20140127352 | FLAVORED DRINKING WATERS AND METHODS FOR IMPROVING HYDRATION FOR ANIMALS - The invention provides flavored drinking water additives and flavored drinking water compositions. The invention also provides methods for increasing water consumption by an animal and improving hydration for animals using the flavored drinking water additives and flavored drinking water compositions of the present invention. | 2014-05-08 |
20140127353 | FLUIDIC FOOD COMPOSITION AND CONFECTIONARY - The purpose of the present invention is to provide: a flowable food composition which contains xylitol in an amount sufficient to obtain excellent sweetness and which can retain the flowability over a long period even when the water content is low; and a confection which is obtained using the flowable food composition. This flowable food composition comprises glycerol, xylitol, which is contained in an amount effective for sweetness, and one or more sugar alcohols excluding xylitol and glycerol. The sugar alcohols preferably comprise one or more compounds selected from the group consisting of sorbitol, maltitol, and reduced palatinose. This confection comprises a center composition which comprises the flowable food composition and a shell composition with which at least some of the center composition is surrounded, the shell composition being selected from the group consisting of candy, chewing gum, and chocolate. | 2014-05-08 |
20140127354 | Method For Preparing A Neutral Malt Base - A method for preparing a neutral alcoholic malt base is disclosed. The method includes the steps of combining malt extract, which can be derived from malted grains containing gluten, or from those that are gluten-free, fermentable sugar in liquid or solid form, and water to form a fermentable medium having a density of greater than 20° Plato, wherein a ratio of the malt extract to the fermentable sugar in the fermentable medium is from 5:95 to 0.1:99.9; and fermenting the fermentable medium with a yeast that can tolerate an alcohol concentration of at least 10% by volume thereby preparing the neutral alcoholic malt base. A flavored malt beverage can include the neutral alcoholic malt base, water, at least one flavoring, a food grade acid, a sweetening agent, and carbon dioxide. | 2014-05-08 |
20140127355 | BREADS HAVING NOVEL PHYSICAL PROPERTIES AND METHOD OF PRODUCING THE SAME - Breads having novel physical properties and a method of producing the breads are provided. Breads produced by fermentation and baking were rebaked after enzyme treatment to acquire breads having novel physical properties having appearance, texture, flavor, etc., equivalent to normal bread and easily chewable and swallowable even by a person having impaired chewing or swallowing functions such as an aged person. | 2014-05-08 |
20140127356 | PROCESS FOR THE MANUFACTURE OF A LEAVENED FOODSTUFF AND AN APPARATUS THEREFOR - The present invention provides a process for the manufacture of a leavened foodstuff, such as a leavened or heat treated leavened foodstuff, and apparatus for the same, wherein in said process an ingredient composition comprising a food structurant, water and a leavening agent is treated with ultrasound from an ultrasound source during at least a part of a leavening step, and/or an ingredient composition comprising a food structurant, water and a leavening agent or a leavened ingredient composition, typically obtained therefrom, is treated with ultrasound from an ultrasound source during at least a part of a heat treating step. | 2014-05-08 |
20140127357 | Method of Manufacturing Artichoke Tea - The present invention provides a method of manufacturing artichoke tea comprising the steps of separating leaf stems, drying the leaf stems at low temperature and performing fermentation, forced-ripening and sugar-preserving processes on the leaf stems of the artichoke. The present invention utilizes the separation to remove the leaves from the leaf stems of the artichoke such that the origin of the taste of bitterness is removed along with the leaves. The leaf stems of the artichoke further undergo drying and fermentation processes such that the water is removed therefrom while preserving the nutrients of the artichoke therein. The forced-ripening and the sugar-preserving processes are further applied to the leaf stems to facilitate the transformation and preservation of the fruitafit-inulin thereof in order to produce a taste of sweetness. The manufactured artichoke tea of the present invention produces no bitterness taste while having nutrients thereof being preserved with enhanced sweet flavor. | 2014-05-08 |
20140127358 | METHODS AND COMPOSITIONS FOR CONSUMABLES - Provided herein are methods and compositions for the production of cheese replicas. Generally the cheese replicas are produced by inducing the enzymatic curdling of non-dairy milks. | 2014-05-08 |
20140127359 | FOOD PRODUCT AND METHOD OF PRESERVING SAME - A food product is within an aqueous solution. The solution includes: at least one edible acid; and at least one osmotic agent, wherein after the solution reaches equilibrium with the food product, the pH of the solution is between about 1 and 5. | 2014-05-08 |
20140127360 | PROCESS - A method of forming flavour particles comprising spraying an emulsion of a flavour material in an aqueous coating material with a core material in a heated environment at a drying temperature, the core material being a finely-divided native starch having a gelatinisation temperature higher than that of the drying temperature. The process allows much quicker and more efficient processing. | 2014-05-08 |
20140127361 | EXTRUDED DELIVERY SYSTEM - The present invention relates to an extruded delivery system. It also relates to a process for preparing such a extruded delivery system. | 2014-05-08 |
20140127362 | COMBINATION FOODSTUFF CONTAINER AND AERIAL TOY - A foodstuff containment and toy apparatus includes a hollow tube having a first opening at a first axial end of the tube, a second opening at a second axial end of the tube, and a length defined between the first and second axial ends. The first and second openings access an interior lumen of the tube. A first removable cover spans the first opening. A second removable cover spans the second opening. A foodstuff is disposed within the interior lumen of the tube and between the first and second removable covers. The tube includes a weighted portion proximate the first axial end such that a center of mass of the tube, without the first and second removable covers and the foodstuff, is located approximately within one-third of the length of the tube nearest the first opening. | 2014-05-08 |
20140127363 | METHOD OF MAKING STRUCTURED PROTEIN COMPOSITIONS - An extrusion process is disclosed for turning vegetable protein compositions such as soy protein into a fibrous, meat-like structure. The process involves the application of relatively high moisture contents. An open structure is produced that can be infused with water so as to influence the product's tenderness. The products of the invention can be provide with a fibrosity and tenderness at will. The invention offers the possibility to include relatively high amounts of fat in the product. | 2014-05-08 |
20140127364 | Beverage Capsule With Moldable Filter - A beverage capsule is provided having a body defining an opening. A filter is disposed in the opening and secured to the body. The filter is moldable to define an ingredients chamber. The filter is formed of a moldable nonwoven fabric comprising fibers that are undrawn or partially drawn prior to molding. Ingredients are disposed in the ingredients chamber for preparing a desired beverage and a cover is disposed over the opening for sealing the interior space. | 2014-05-08 |