18th week of 2021 patent applcation highlights part 14 |
Patent application number | Title | Published |
20210128844 | DELIVERY DEVICES FOR ADMINISTERING DRUGS - An example drug delivery device includes a syringe assembly including a needle. The drug delivery device includes a handle carrying the syringe assembly and including a first portion, a second portion, a tapered surface, and a window. The first portion being wider than the second portion. The tapered surface extending from the first portion to the second portion. The needle of the syringe assembly adapted to extend from adjacent the second portion during an injection procedure. The window positioned between the first portion and the second portion and adapted to allow contents of the drug delivery device to be viewed. The drug delivery device includes a base adapted to be positioned adjacent the second portion of the handle during at least the injection procedure. The base being wider than the second portion of the handle and adapted to increase stability of the drug delivery device during the injection procedure. | 2021-05-06 |
20210128845 | DEVICE AND METHOD FOR INJECTING MEDICINE - According to an embodiment, a medicine injection device comprises a medicine storage unit receiving a medicine cartridge storing a medicine, a needle unit connected with the medicine cartridge and injecting the medicine to a user, a driver configured to apply an external force to the medicine storage unit, a temperature sensor measuring a temperature of at least one of the medicine storage unit, the needle unit, the driver, and an outside of the medicine injection device, and a controller determining a medicine state indicating whether the medicine deteriorates based on the temperature measured by the temperature sensor and controlling the driver according to the determined medicine state to thereby determine whether to block the injection of the medicine. | 2021-05-06 |
20210128846 | INSUFFLATION SYSTEM - An aerosol generator is positioned adjacent to a patient as an attachment to a trocar. The trocar has an entry port for insufflation gas. Aerosol generated by a vibrating element is entrained in the insufflation gas and the mixture is delivered through the trocar. The aerosol may contain a medicament. The trocar may be a conventional trocar. Such trocars are typically used for a camera. The delivery of the aerosolized medicament can occur at the start of the procedure and be delivered in bolus. At the start of the procedure, the peritoneum is being inflated by means of the flow of insufflator gas. This gas flow will help to entrain the aerosolized medicament to the pneumoperitoneum regions. The surgeon can temporarily remove the camera from the trocar port to facilitate insertion and positioning of the aerosolizing unit. | 2021-05-06 |
20210128847 | Carboxy Therapy Applicator - Handheld carboxy therapy applicators are disclosed. In one implementation, a handheld carboxy therapy applicator includes a heater module, a humidification module, and a hypodermic needle. The heater module is configured to receive a flow of gas and to warm gas within the flow of gas. The humidification module is in fluid communication, such as in a serial connection, with the heater module. The humidification module is configured to receive the flow of gas from the heater module and to humidify the gas within the flow of gas. The hypodermic needle is in serial connection with the humidification module. The hypodermic needle is configured to receive the flow of gas from the humidification module and to inject the flow of gas into a tissue of a patient. | 2021-05-06 |
20210128848 | INHALER MOUTHPIECE DEVICE - The present invention relates to an inhaler mouthpiece device for use as an accessory aid for metered dose inhalers and spacers used along with such inhalers. The device removably attachable to the metered dose inhaler simplifies and assists a patient's inhaling effort to advance an inhaled medication into lungs of the patient. | 2021-05-06 |
20210128849 | NASAL CANNULA AND TUBING MEDICINE DELIVERY SYSTEM - A nasal cannula system having nasal prongs with an ancillary delivery system for a treatment fluid into a patient wearing the nasal cannula without removing the cannula. The nasal prongs have parallel ports that fluidly connect the delivery system to the nasal ports on the nasal prongs. The delivery system provides the treatment fluid in an aerosolized form. This configuration combines the aerosolized treatment fluid with the air or other fluid ordinarily delivered by the nasal cannula. The system may also use airway tubes having a generally semi-circular cross-section with an internal rib extending the length of the tube. The semi-circular cross-section provides a flat exterior surface for abutment or contact with a patient's skin and the rib prevents pinching closure of the airway tube. | 2021-05-06 |
20210128850 | Rebreathing Apparatus Having Inhaled Oxygen Mixing And Exhaled Carbon Dioxide Removal Functions By Electronic Control - A rebreathing apparatus having inhaled oxygen mixing and exhaled carbon dioxide removal functions, enabling rebreathing by maintaining the amount of breathing oxygen by inhalation and removing carbon dioxide discharged by exhalation. The rebreathing apparatus includes a mask having one side to which an inhalation hose is connected and the other side to which an exhalation hose is connected; an exhaled breath storing container storing exhaled breath; a filter removing carbon dioxide; an inhaled breath storing container storing the air having passed through the filter; an oxygen storing container supplying oxygen to the inhalation storing container; a decompressor installed at an inlet of the oxygen storing container; an oxygen mixing module mixing the oxygen discharged through the oxygen supplying hose with the air; and a controller controlling operations of the exhaled breath storing container, the inhaled breath storing container, the oxygen storing container, the filter, and the oxygen mixing module. | 2021-05-06 |
20210128851 | RESPIRATORY ASSISTANCE PROGRAM AND RESPIRATORY ASSISTANCE DEVICE - A program for controlling a respiratory assistance device that is connected to a user's airway and regulates an airway pressure to assist ventilation has a plurality of different respiratory assistance modes. The respiratory assistance program causes a computer to realize an input reception function that receives an input of setting for a respiratory assistance mode during operation of an air blower that blows air to the user's airway, and a flow rate control function that, when the input reception function receives the input of setting, controls a flow rate from the air blower in reflection of a result of the input of setting. A respiratory assistance device in which a user can change setting to select a comfort pressure and flow rate is provided by using such a program. | 2021-05-06 |
20210128852 | SYSTEM FOR DETECTION OF LEAKAGE OR ABNORMAL RESISTANCE IN A VENTILATION SYSTEM - The present disclosure relates to a system for detection of leakage or abnormal resistance in a ventilation system ( | 2021-05-06 |
20210128853 | Ventilator Comprising Operating Device Having Haptic Feedback - The present invention relates to a ventilation device ( | 2021-05-06 |
20210128854 | METHOD FOR DRIVING NEBULIZER AND CIRCUIT SYSTEM - A method and a circuit system for driving a nebulizer are provided. When the nebulizer receives acoustic waves, a control circuit extracts audio signals from the acoustic waves. Afterwards, the control circuit determines if the audio signals are within a predetermined frequency range, and can determine whether or not to drive a circuit to produce an aerosol based on the audio signals. Further, a volume of the acoustic waves can also be used to determine whether or not to produce the aerosol, and also determine an output rate of the aerosol. The circuit system of the nebulizer includes an audio receiver for receiving the acoustic waves, an aerosol generator for producing the aerosol, and the control circuit used to control a driving circuit of the aerosol generator to drive a vibrational element to produce the aerosol through vibration in response to the audio signals and the volume. | 2021-05-06 |
20210128855 | INTEGRATED MULTIMODAL COLORIMETRIC BASED ASPIRATION DETECTION AND INTUBATION PLACEMENT VERIFICATION SYSTEM AND METHOD - An integrated multimodal colorimetric based aspiration detection and intubation placement verification system for an endotracheal tube and associated method includes a housing configured to be coupled to the endotracheal tube whereby patient exhalation can flow through an internal passage of the housing, and colorimetric based sensors within the housing and configured to come into contact with the patient exhalation, where the colorimetric based sensors are visible from the exterior of the housing, and wherein the colorimetric sensors include at least two of i) CO2 sensor, ii) a sensor for a first gastric acid, iii) a sensor for a second gastric acid different from the first gastric acid, and iv) a PH sensor. An associated method is disclosed. The integrated multimodal colorimetric based system can be used with other respiratory devices other than endotracheal tubes. | 2021-05-06 |
20210128856 | BALLOONED VENTILATION TUBE CLEANING DEVICE - A cleaning device, system and method for use with an ETT or tracheostomy ventilation tube | 2021-05-06 |
20210128857 | THREE-CAVITY FLUSHABLE FISH MOUTH LARYNGEAL MASK AIRWAY CATHETER - Disclosed is a three-cavity flushable fish mouth laryngeal mask airway catheter, including a cover, the cover is provided with a respiratory chamber for communicating with a respiratory tract and a digestive chamber for communicating with a digestive tract; the digestive chamber is provided with a digestive opening for communicating the digestive chamber and the digestive tract; a peripheral wall of the digestive chamber is tapered from an end away from the digestive opening to the digestive opening; an edge of the digestive opening includes a plurality of protrusions; and the plurality of protrusions are configured to be close to each other due to a squeezing force during a process of inserting the three-cavity flushable fish mouth laryngeal mask airway catheter into a throat to narrow the digestive opening. | 2021-05-06 |
20210128858 | TRACHEO-BRONCHIAL SAMPLING DEVICE - A tracheal sampling device is used to collect or acquire cells from an animal, such as at or near the tracheo-bronchial or larynx of an animal. The device includes a flexible and elongated shaft or stem, and a collection member at a distal end of the device. The collection member could be a swab or other member to best collect mucus. The device is used by inserting the collection end into an animal to position the collection member at or near the cell collection site, which may be in or around the larynx. The collection member is removed after collecting cells, which can be reviewed, tested, or otherwise managed to determine the presence of a disease or other bacteria. The length of the shaft or stem allows for optimal positioning of the swab in a variety of animal species and ages. The device can be disposed after each use. | 2021-05-06 |
20210128859 | METHOD FOR INTUBATION USING REMOTE VIDEO MONITOR - A manually articulated stylet assembly for placing an endotracheal tube. The stylet assembly has a steering shaft that carries a flexible distal tip at one end and is attached to a handle at the other end. The distal tip is manipulated via sheathed cables controlled by a remote actuator in the handle. A biasing member inside the remote actuator maintains continuous tension on the cables to improve control. A video camera is carried in a recessed lens pocket in the steering shaft but spaced from the distal tip. The camera FOV captures movement of the distal tip with foreshortened perspective. A collar seat in the handle receives the collar connector of a standard endotracheal tube, providing quick disconnect when removing the stylet assembly upon placement. | 2021-05-06 |
20210128860 | ENDOTRACHEAL TUBE FIXATION - A fixation device ( | 2021-05-06 |
20210128861 | MASK - A mask is disclosed that has a gas outlet which is quiet and provides for a diffused outlet flow of gases. The outlet is preferably a slot formed between a hollow body and cover over said hollow body. The mask also preferably extends and seals under a user's chin in use. | 2021-05-06 |
20210128862 | CUSHION WITH BUCKLING PREVENTION STRUCTURE - A cushion for use in a system providing a flow of breathing gas to the airway of a patient includes a first end having a sealing flap structured to sealingly engage a surface of the patient about an airway of the patient and a second end adapted to receive the flow of breathing gas. A wall portion extends between the first end and the second end and defines a passage which extends between the first end and the second end and which is structured to communicate the flow of breathing gas from the second end to the first end. The wall portion includes a notch which is positioned and structured to deform in a predetermined manner such that an angle which the wall portion makes with a longitudinal axis of the passage increases from a first value to a second value upon deformation of the notch. | 2021-05-06 |
20210128863 | NASAL CANNULA AND TUBING WITH VENTILATOR SYSTEM - A nasal cannula system for use in ventilator systems, particularly continuous positive airway pressure (CPAP) systems. The nasal cannula system has a nasal body with nare prongs that extend into a patient's nostrils when worn. The ventilator system includes a ventilator on an inhalation side and either a bubble chamber or a variable resistance valve on the exhalation side. The inhalation side may include a heater/humidifier in-line with the supply tube so as to treat the air before application. The airway tube may have a generally semi-circular cross-section so as to provide a flat exterior surface for abutment or contact with a patient's skin. | 2021-05-06 |
20210128864 | OXYGEN RECOVERY DURING NASAL THERAPY - A system includes an oxygen supply; one or more sensors configured to generate output signals conveying information as to whether the patient is in an inspiratory phase or in an expiratory phase; one or more valves; and a computer system. The one or more valves have a) a first configuration in which the one or more valves operate to recover an excess flow of the oxygen-enriched breathing gas during the inspiratory phase, and b) a second configuration in which the one or more valves vent an exhalation flow of the patient during the expiratory phase to atmosphere. One or more physical processors are programmed with computer program instructions which, when executed cause the computer system to provide input to the one or more valves based on the output signals, the provided input causing movement of the one or more valves between the first and second configuration. | 2021-05-06 |
20210128865 | CONFIGURABLE OXYGEN CONCENTRATOR AND RELATED METHOD - A configurable oxygen concentrator for providing various flow rates and volumes of concentrated oxygen to a patient includes an electro-mechanical assembly having a housing with a first face, a second face and an outer surface. The oxygen concentrator also includes a first battery, a second battery, a first adsorbent container and a second adsorbent container. The first and second batteries are removably mountable to the first face and the first and second adsorbent containers are removably mountable to the second face to permit modification of the concentrated oxygen capacity and operating life of the concentrator as the patient progresses through different stages of a breathing disease. The first battery has a first battery capacity that is less than a second battery capacity of the second battery. The first adsorbent container has a first adsorbent capacity that is less than a second adsorbent capacity of the second adsorbent container. | 2021-05-06 |
20210128866 | HUMIDIFICATION DEVICE AND RESPIRATORY HUMIDIFICATION AND BLOWING APPARATUS INCLUDING THE SAME - A humidification device ( | 2021-05-06 |
20210128867 | SYSTEM AND METHOD FOR DETERMINING WHETHER A SUBJECT IS LIKELY TO BE DISTURBED BY THERAPY LEVELS OF STIMULATION DURING SLEEP SESSIONS - The present disclosure pertains to a system and method for determining whether a subject is likely to be disturbed by therapy levels of stimulation provided to the subject during sleep sessions. The present system is configured to automatically identify sensitive users using electroencephalogram (EEG) information from a reference sleep session with or without stimulation. For reference sleep sessions without stimulation, the alpha activity in detected deep sleep is used to predict whether the subject is likely to be disturbed by therapy levels of stimulation. For reference sleep sessions with stimulation, the acute increase in EEG delta (e.g., 0.5-4 Hz) power and/or an arousability index are used to predict whether the subject is likely to be disturbed by therapy levels of stimulation. | 2021-05-06 |
20210128868 | MOBILE TERMINAL, FRAGRANCE GENERATION DEVICE, SERVER, FRAGRANCE DETERMINATION METHOD, AND PROGRAM - A fragrance suitable for a user can be provided. A mobile terminal includes: an acquisition unit that acquires a psychosomatic state from a physiological index of a user; an input unit that inputs future information of the user; a determination unit that determines a recipe including one or more types and a mixing ratio of one or more perfumes based on the psychosomatic state and the future information; and a communication unit that transmits the recipe to a fragrance generation device. | 2021-05-06 |
20210128869 | Catheter Patency Device - Briefly summarized, embodiments disclosed herein are directed to apparatus and methods for removing an occlusion from an indwelling catheter. The system can include a pressurized fluid conduit for delivering pressurized fluid to an occlusion site, and ablating the occlusion. A negative pressure source in fluid communication with the catheter lumen can then aspirate the occlusion. The positive pressure source can provide a pulsed pressurized fluid to facilitate ablation. The system can also include tip tracking and tip location systems to ensure the pressurized fluid conduit does not extend beyond the catheter lumen, causing damage to the vasculature. The system can further include an ultrasound transducer, coupled with one of the catheter and the pressurized fluid conduit to provide ultrasonic wave energy to the occlusion to further facilitate ablation thereof. | 2021-05-06 |
20210128871 | GUIDEWIRE ASSEMBLY DETECTABLE BY MEDICAL-IMAGING SENSOR - A flexible guidewire assembly has an energy-emitting device configured to be selectively activated in response to receiving a first activation signal transmittable from a control assembly. This is done in such a way that the energy-emitting device, once activated, emits a first amount of electro-magnetic energy. The first amount of electro-magnetic energy has a first strength that is (A) sufficient for detection by a medical-imaging sensor positioned in the confined space defined by the living body, and (B) insufficient for vaporization of any tissue of the living body. | 2021-05-06 |
20210128872 | GUIDEWIRE COILS WITH DIFFERENT CROSS SECTION SHAPES - A guidewire for use in intravascular procedures has an inner coil that is radiopaque and an outer coil that is non-radiopaque at the distal end of the guidewire. The radiopaque inner coil is visible under fluoroscopy so that the physician can monitor the location of the distal end of the guidewire during a procedure. The inner coil and the outer coil can be formed from a single wire or a multi-filar wire. The inner coil and the outer coil can have any of the following cross-sections for enhanced torquability: I-beam; vertical rectangular; vertical ellipse; square; peanut shape; vertical hexagonal; horizontal hexagonal; and horizontal ellipse. | 2021-05-06 |
20210128873 | ENDOSCOPIC CATHETER DEVICE - A device may include a catheter and a support tube. The catheter includes a lumen extending therethrough. The catheter is sized and shaped to extend through an endoscopic shaft to a target tissue within a living body. The lumen is sized and shaped for receiving a puncturing device therethrough. The catheter includes a first catheter portion distal to a second catheter portion. The first and second catheter portions are formed from different materials. The first catheter portion has a flexible curved distal end. The tube is fixed about an outer surface of a proximal end of the first catheter portion and an outer surface of a distal end of the second catheter portion. | 2021-05-06 |
20210128874 | GUIDEWIRE HAVING PARABOLIC GRIND PROFILE - A guidewire for use in intravascular procedures has an elongated core member including a proximal core section having a uniform diameter. One or more parabolic grind profile sections extend distally from the distal end of the proximal core section and provide a linear change in bending stiffness and a high degree of torque to the distal portion of the guidewire. | 2021-05-06 |
20210128875 | GUIDEWIRE TIP SHAPING TOOL - A shaping tool is used to form a bend in the distal end of a guidewire. The guidewire distal end is inserted through a channel and into a cavity of the shaping tool. Using hand pressure, a first member is moved axially relative to a second member of the shaping tool, thereby moving the cavity relative to the channel and imparting a bend in the distal end of the guidewire. | 2021-05-06 |
20210128876 | MIXER SHEATH FOR A VASCULAR CATHETER - The application relates to vascular catheters, in particular to vascular catheter systems ( | 2021-05-06 |
20210128877 | INTRALUMINAL DEVICE WITH LOOPED CORE WIRE - Intraluminal and endovascular devices and methods of manufacturing intraluminal and endovascular devices may be provided. In one implementation, an intraluminal device may include a sheath having a flexible distal bending segment and a core wire arranged within the sheath. The core wire may include a distal end portion doubled back in a loop within the sheath such that the distal tip of the core wire is situated proximally from the loop. The intraluminal device may also include a movement restrictor within the sheath that is configured to limit axial movement of the distal tip of the core wire. Limiting the axial movement of the core wire distal tip may cause the loop of the core wire to buckle, resulting in a bend in the distal bending segment of the sheath, when a force is exerted on the core wire. | 2021-05-06 |
20210128878 | CATHETER WITH ADJUSTABLE DEFLECTION - A catheter having a catheter shaft that has a more uniform construction throughout its length and is able to provide more than one deflection curvature. The catheter shaft includes a flexible outer tubular member, and a less flexible inner tubular member extending through the outer tubular member in a proximal section of the catheter shaft, wherein the inner tubular member is afforded longitudinal movement relative to the outer tubular member. The catheter also includes at least one puller wire extending through the inner tubular member to deflect a distal deflection section of the catheter shaft, wherein longitudinal movement of the inner tubular member relative to the outer tubular member enables an operator to select and set a deflection curvature of the distal deflection section. | 2021-05-06 |
20210128879 | CATHETER FOR DIALYSIS, IN PARTICULAR FOR LONG-TERM APPLICATION - The invention relates to a catheter for dialysis, in particular for long-term application, comprising a proximal end for introducing into a blood vessel, a distal end for extracting blood and for introducing purified blood, and at least one fixing means surrounding a tube section for fixing the catheter on the patient. The fixing means has a receiving part and an opening part, wherein, with respect to the receiving part, the opening part can be moved from an opening position, in which the tube section is insertable into the fixing means, into a closing position, in which the tube section is fixed in the fixing means. | 2021-05-06 |
20210128880 | Catheter Securing Devices and Methods - A device that has a head having an inside surface and a base integral with the head, the head smoothly transitioning to the base, the base comprising a first opening where the head transitions to the base and a lateral circular channel that travels from the first opening to a second opening on a bottom of the base. Further, the device has a clamp that clamps the base to a catheter. | 2021-05-06 |
20210128881 | SYSTEMS AND METHODS FOR ANCHORING MEDICAL DEVICES - Some embodiments of a medical device anchor system include an anchor device that secures a medical instrument (such as a catheter or the like) in place relative to a skin penetration point using subcutaneous anchors. | 2021-05-06 |
20210128882 | CATHETER SYSTEM AND METHOD OF INTRODUCING AN INTRAVENOUS CATHETER INTO A PATIENT - A catheter system and method of introducing an intravenous catheter into a patient includes a syringe, an access needle, a pliable catheter, and a guidewire. The syringe has a first chamber and a distal syringe end portion, which defines a conduit distally extending to a distal syringe opening such that the conduit fluidly connects the first chamber to the distal syringe opening. The access needle defines a needle lumen longitudinally extending therethrough and is secured relative to the distal syringe end portion. The pliable catheter is releasably secured relative to the access needle. The guidewire distally extends through the conduit toward the distal syringe opening and is configured to selectively move through the conduit, the distal syringe opening, and along the needle lumen to thereby guide movement of the pliable catheter relative to the access needle for introducing the pliable catheter into the patient. | 2021-05-06 |
20210128883 | GUIDEWIRE HAVING RADIOPAQUE INNER COIL - A guidewire for use in intravascular procedures has an inner coil that is radiopaque and an outer coil that is non-radiopaque at the distal end of the guidewire. The radiopaque inner coil is visible under fluoroscopy so that the physician can monitor the location of the distal end of the guidewire during a procedure. The inner coil and the outer coil can be formed from a single wire or a multi-filar wire. The inner coil and the outer coil can have any of the following cross-sections for enhanced torquability: I-beam; vertical rectangular; vertical ellipse; square; peanut shape; vertical hexagonal; horizontal hexagonal; and horizontal ellipse. | 2021-05-06 |
20210128884 | MOLD FOR FORMING SOLDER DISTAL TIP FOR GUIDEWIRE - A mold is used to form a solder joint to join the distal end of the guidewire to a wire coil. The mold has a cavity that can have different configurations so that the solder joint can be any of bullet shaped, micro-J shaped, cone shaped, truncated cone shaped, or have a textured surface. | 2021-05-06 |
20210128885 | MEDICAL DEVICES WITH REINFORCED WIRES - A medical device includes: a wire having a proximal end, a distal end, and a body extending between the proximal end and the distal end; and a coil disposed around a segment of the wire, wherein the coil comprises a proximal coil end, a distal coil end, and a coil body extending between the proximal coil end and the distal coil end; wherein the coil body comprises loops made from an elongated member having a cross-section, wherein the cross-section of the elongated member comprises a first side facing the wire, and a second side being opposite the first side and facing away from the wire; and wherein the second side of the cross-section of the elongated member has a higher curvature than the first side of the cross-section of the elongated member. | 2021-05-06 |
20210128886 | GUIDE WIRE - A guide wire including a first core shaft made of a superelastic material, and a second core shaft made of a material more susceptible to plastic deformation than of the first core shaft and joined to a distal end side of the first core shaft on a proximal end side. On a joint part between the first core shaft and the second core shaft, the first core shaft and the second core shaft are adjacent to each other in a first direction. A flat portion where a length in the first direction in a transverse section is longer than a length in a second direction orthogonal to the first direction is formed on a distal end portion of the second core shaft. | 2021-05-06 |
20210128887 | GUIDE WIRE, AND GUIDE WIRE MANUFACTURING METHOD - A guide wire including a first core shaft, a second core shaft, a covering member, and a joint layer. The first core shaft has a first large-diameter portion and a first small-diameter portion, and the second core shaft has a second large-diameter portion and a second small-diameter portion. The covering member covers a contact portion where the first and second small-diameter portions are arranged opposite to each other, and at least a part of each of the first and second small-diameter portions are adjacent to the contact portion. The joint layer joins the covering member with the first and second small-diameter portions inside the member. A length of the covering member is shorter than a sum of the lengths of the first and the second small-diameter portion in the axial direction, and longer than the shorter of the lengths of the first and second small-diameter portions in the axial direction. | 2021-05-06 |
20210128888 | Systems and Methods for Steering Guidewires - Embodiments of the present disclosure can include a system for steering a guidewire comprising: a guidewire tip integrably connected to a guidewire, the guidewire tip comprising a hollow body having first joint and second joints comprising a plurality of asymmetric recesses in the hollow body; a plurality of tendons operably connected to the first and second joints; and a control unit operably connected to the tendons and configured to actuate the tendons to provide multiple degrees of freedom of movement to the guidewire tip. | 2021-05-06 |
20210128889 | GUIDE WIRE HOLDER - A guide wire holder includes a sheath having a lumen, an operation wire which is inserted through the lumen to be able to advance and retract, and a hook which is continuous with a distal end of the operation wire and protrudes from a distal end of the sheath, wherein the sheath has an inner wall surface which forms a groove configured to extend from the distal end of the sheath to a proximal end side of the sheath, the groove has an opening portion which opens to an outer peripheral surface of the sheath, the hook has a guide wire engagement surface which is engageable with a guide wire, and the guide wire is able to be held between the guide wire engagement surface and the inner wall surface. | 2021-05-06 |
20210128890 | MEDICAL BALLOON WITH RADIOPAQUE END PORTION FOR PRECISELY IDENTIFYING A WORKING SURFACE LOCATION - A balloon catheter comprises an elongated, tubular shaft extending in a longitudinal direction, said shaft having a proximal end and a distal end. An inflatable balloon is supported along the distal end of the shaft, the balloon when inflated including a generally cylindrical barrel section forming a working surface, and generally conical end sections that do not form a part of the working surface. The balloon further includes at least one radiopaque identifier for indicating the relative position of the working surface, said identifier being provided on at least one of the conical end sections of the balloon so as to define the extent of the working surface. Related aspects are also disclosed. | 2021-05-06 |
20210128891 | BALLOON CATHETER - A balloon catheter and methods of using same are provided. The balloon catheter can include an expandable structure mounted over a balloon coated with a composition. The expandable structure includes a plurality of axial struts crossing a plurality of radially-expandable rings for constraining the balloon such that isolated balloon regions can protrude through openings in the expandable structure when the balloon is inflated. The balloon catheter can be configured to maximize scraping of the composition from the surface of the balloon by the struts of the expandable structure during balloon inflation. | 2021-05-06 |
20210128892 | METHODS FOR MANUFACTURING MULTI-LAYER BALLOONS FOR MEDICAL APPLICATIONS - A multi-layered balloon is provided where each layer is formed such that each layer is made from tubing that optimizes the inner wall stretch thus providing maximum balloon strength. The high pressure, multi-layer balloon is provided with layers that allow for slipping, such that the balloon has a very high pressure rating and toughness, yet excellent folding characteristics. Methods for producing such multi-layer balloons using existing balloon forming equipment are also provided. The multi-layer balloons can have alternating structural and lubricating layers, or layers with low-friction surfaces. The multi-layer balloons are preferably manufactured using a variety of methods including nesting, co-extrusion, or a combination of nesting and co-extrusion. The multi-layer balloons have balloon layers having substantially similar, or the same, high degree of biaxial orientation of their polymer molecules such that each balloon layer of the multi-layer balloon will fail at approximately the same applied pressure. | 2021-05-06 |
20210128893 | THROMBUS REMOVAL DEVICE - In some examples, a catheter assembly includes a delivery catheter defining a delivery catheter lumen, a delivery catheter handle connected to the delivery catheter, a retrieval catheter defining a retrieval catheter lumen configured to receive the delivery catheter, and a retrieval catheter handle connected to the retrieval catheter. A proximal end of the retrieval catheter handle is configured to removably couple to a distal end of the delivery catheter handle. | 2021-05-06 |
20210128894 | System and Method for Accelerating Cervical Ripening - A cervical ripening system includes a balloon catheter and a fluid pump. The fluid catheter has a balloon portion configured to pass through a cervix when contracted and to engage and pressure a uterine side of the cervix when expanded by fluid. The fluid pump is in fluid flow communication with the balloon portion of the catheter and is configured to selectively expand and contract the balloon portion of the balloon catheter by alternately pumping fluid into and out of the balloon portion of the balloon catheter to repetitively increase and decrease pressure on the uterine side of the cervix to simulate natural uterine contractions. | 2021-05-06 |
20210128895 | DEVICE - Disclosed is a drug delivery device comprising a body for holding a first solution and a second solution which are independent with each other; a pipeline delivery system comprising one or more pipelines for independently delivering the first solution and the second solution, respectively; a press device for sucking the first solution and the second solution into the pipelines, and a nozzle for delivering the first solution and the second solution in the pipelines to an administration site such that the first solution covers the second solution at the administration site. | 2021-05-06 |
20210128896 | METHOD FOR TREATING SKIN - The present invention relates to a method for treating skin, comprising the following step A) and then step B):
| 2021-05-06 |
20210128897 | BONE GROWTH STIMULATOR AND METHODS OF USE - The present invention relates to a device. The device includes an elongate handle having a proximal end and a distal end; a head portion extending from the proximal end of the elongate handle, the head portion having a first interior-facing surface and an opposing second exterior-facing surface; and a plurality of microneedles extending from, and perpendicular to, the first interior-facing surface of the head portion. Each of the plurality of microneedles has a base connected to the first interior-facing surface of the head portion and a free tip end. The present invention also relates to a method for stimulation of cortical bone formation using the device of the present invention. | 2021-05-06 |
20210128898 | METHODS AND COMPOSITIONS FOR TREATING SKIN - The present disclosure generally relates to methods and compositions for treating skin. In some embodiments, the method uses an exfoliation tool. In some embodiments, the method uses an exfoliation tool together with selected skin care agents or compositions. | 2021-05-06 |
20210128899 | ATRAUMATIC SUBCUTANEOUS MEDICATION DELIVERY - An atraumatic trocar apparatus, system, kit, and method of use are described. The atraumatic trocar apparatus includes a cannula and an insertion obturator with an anterior rounded tip. The atraumatic trocar apparatus is assembled by passing the insertion obturator through an interior passage of a tubular cannula body of the cannula. The assembled atraumatic trocar is used to probe an incision to reach a delivery site within a patient's subcutaneous tissue. The insertion obturator is removed from the cannula and two or more medication pellets loaded within the interior passage. The insertion obturator is used to push the medication pellets through the interior passage to the delivery site and deposit the medication pellets within the patient's subcutaneous tissue in a non-linear delivery pattern. | 2021-05-06 |
20210128900 | INTRATHECAL CATHETER WITH FEATURES TO REDUCE DRUG DISPERSION - A medical device configured to restrict medicament dispersion within a cerebrospinal fluid flow of the patient. The medical device including an implantable catheter having a distal end configured to be positioned within a flow of the cerebrospinal fluid, a proximal end, a body defining a lumen extending lengthwise along the implantable catheter configured to enable a flow of medicament from the proximal end to an infusion port located in proximity to the distal end, and a contoured surface defined by an exterior of the body in proximity to the infusion port configured to inhibit dispersion of the medicament within the cerebrospinal fluid. | 2021-05-06 |
20210128901 | Hemodynamic Assist Device - A hemodynamic flow assist device includes a miniature pump, a basket-like cage enclosing and supporting the pump, and a motor to drive the pump. The device is implanted and retrieved in a minimally invasive manner via percutaneous access to a patient's artery. The device has a first, collapsed configuration to assist in implantation and a second, expanded configuration once deployed and active. The device is deployed within a patient's aorta and is secured in place via a self-expanding cage which engages the inner wall of the aorta. The device includes a helical screw pump with self-expanding blades, sensors, and anchoring structures. Also disclosed is a retrieval device to remove the hemodynamic flow assist device once it is no longer needed by the patient and an arterial closure device to close the artery access point after implantation and removal of the hemodynamic flow assist device. The hemodynamic flow assist device helps to increase blood flow in patients suffering from congestive heart failure and awaiting heart transplant. | 2021-05-06 |
20210128902 | Blood Pump Device - Disclosed is a blood pump device. The blood pump device includes: a housing having an overflow passage, and an inlet and an outlet respectively connected to the overflow passage; a rotor assembly rotatably disposed in the overflow passage; a coil disposed in a side wall of the housing; a first permanent magnet portion disposed inside the rotor assembly; a second permanent magnet portion disposed in the side wall of the housing, the first permanent magnet portion and the second permanent magnet portion forming a radial permanent magnet bearing; a piece of electric motor magnetic steel disposed inside a rotor of the rotor assembly; and a magnetic protection portion disposed at a periphery of the coil, wherein the magnetic protection portion and the electric motor magnetic steel act together to provide an axial pre-tightening force for the rotor assembly. | 2021-05-06 |
20210128903 | ROTARY BLOOD PUMP - A centrifugal blood pump includes a housing having a pumping chamber, an inlet having an inlet axis, and an outlet having an outlet axis. The inlet and the outlet are in fluid communication with the pumping chamber. The pump further includes an impeller rotatably disposed within the pumping chamber, and a strut connected to the housing at the inlet. The strut is connected to the housing at a circumferential position about the inlet axis such that a major axis of the strut and the outlet axis define a predetermined angle in a cross-sectional plane perpendicular to the inlet axis. The circumferential position of the strut relative the outlet axis reduces or eliminates damage to blood flowing around the strut. | 2021-05-06 |
20210128904 | ELECTROSTIMULATION APPARATUS - An electrostimulation method of at least one muscle group responsible for performing a complex movement includes associating to each of the muscles of the at least one muscle group an electrostimulation channel provided with at least one respective electrode. Each electrostimulation channel is suitable to transmit to the respective muscle bipolar electrical pulses in sequence. For all the electrostimulation channels, a same cycle time defining a repeatable period of stimulation is determined, in which, within the stimulation period, each channel performs its own stimulation sequence. Each stimulation period is sub-divided into two half-periods of equal duration. Each half-period is sub-divided into sub-intervals of the same duration. At least one of the sub-intervals is a stimulation sub-interval wherein a basic sequence of pulses including one or more pulse packets is performed, each pulse packet being given by a predetermined sequence of individual bipolar electric pulses. | 2021-05-06 |
20210128905 | KIT AND SYSTEM FOR TRANSCRANIAL BRAIN STIMULATION - A kit for transcranial brain stimulation is disclosed. The kit comprises a headset for transcranial brain stimulation, and a non-transitory computer-readable recording medium having recorded thereon a program which is executable on an electronic device having processing capabilities. The program comprises program code portions which when executed on the electronic device is configured to: store, in a computer memory, a schedule for performing the transcranial brain stimulation; and generate a control signal for the headset such that transcranial brain stimulation is performed according to the schedule for performing the transcranial brain stimulation. The headset comprises: a wireless transceiver configured to wirelessly communicate with the electronic device; a circuit comprising a first electrode, a second electrode and a power source configured to provide power to the circuit; and a controller being configured to control powering of the circuit according to the control signal. | 2021-05-06 |
20210128906 | Systems and Methods for Using Transcutaneous Electrical Stimulation to Enable Dietary Interventions - The disclosed electrical stimulation system generates interventions to assist patients in complying with a diet. The wearable device includes a microprocessor, electrical stimulator and at least one electrode configured to deliver electrical stimulation to the epidermis, through a range of 0.1 mm to 10 mm or a range of 0.1 mm to 20 mm of the dermis, of a T2 dermatome to a T12 dermatome or meridian of the patient, a C5 to a T1 dermatome across the hand and/or arm, and/or the upper chest regions. The device is adapted to provide electrical stimulation as per stimulation protocols and to communicate wirelessly with a companion control device configured to monitor and record appetite patterns of the patient and generate interventions. The control device is also configured to monitor, record, and modify stimulation parameters of the stimulation protocols. | 2021-05-06 |
20210128907 | PULL WIRE DISPLACEMENT ASSEMBLIES AND METHODS - An exemplary pull wire displacement assembly includes a housing, a proximal wire stay, a distal wire stay, a slider pin, and a track. The proximal wire stay is configured to statically affix to a pull wire. The distal wire stay is configured to slidably affix to the pull wire in a manner that allows the pull wire to pass through the distal wire stay while substantially constraining radial displacement of the pull wire. The slider pin is configured to slide along the track in response to a sliding force. The track is configured to direct the slider pin along a trajectory that crosses a straight line between the proximal and distal wire stays such that, when the slider pin slides along the trajectory, the slider pin progressively displaces the pull wire away from the straight line to thereby pull the pull wire toward the housing through the distal wire stay. | 2021-05-06 |
20210128908 | LEADLESS CARDIAC PACING DEVICES - Implantable leadless pacing devices and medical device systems including an implantable leadless pacing device are disclosed. An example implantable leadless pacing device may include a pacing capsule. The pacing capsule may include a housing. The housing may have a proximal region and a distal region. A first electrode may be disposed along the distal region. One or more anchoring members may be coupled to the distal region. The anchoring members may each include a region with a compound curve. | 2021-05-06 |
20210128909 | ELECTRICAL SYSTEM COMPRISING A PLURALITY OF ELECTRIC CIRCUITS AND ANTI-CURRENT PROTECTION EQUIPMENT - Aspects of the present disclosure are directed to increasing protection against electric shocks when a person is working on an electrical system. In some embodiments, the electrical system includes at least two different circuits and a safety module. An emergency signal input is provided on the safety module, and when an external emergency signal is received via the emergency signal input, the safety module shuts off a configured first circuit the associated switch and at least one further circuit via the associated switch if the safety module still receives the emergency signal at the emergency signal input after a predetermined period of time. | 2021-05-06 |
20210128910 | ELECTROPORATION PROBE - An electroporation probe has a housing supporting needles electrically linked to a coupler for an electrical drive. A cap has apertures in a distal face and aligned with the needles. The cap is movable longitudinally against a spring bias relative to the needles to allow insertion by the needles in use as the cap is pressed against patient tissue. There is a limit feature for abutting a limiter setting maximum extent of longitudinal movement relative to the housing. This allows the probe to be presented by the physician without the needles protruding and for them to be inserted up to the user-set maximum extent with maintenance of spacings due to the guiding action of the cap pressed against the tissue surface. | 2021-05-06 |
20210128911 | ELECTROPORATION DEVICE - An electroporation device for injecting a product into a ciliary muscle of an eye includes a support having a spherical support contact surface extending along a virtual sphere having a radius between 10 and 15 mm, a first electrode comprising a curved invasive electrode needle, a second electrode having an electrically conductive electrode contact surface, and an injection needle. | 2021-05-06 |
20210128912 | WEARABLE MEDICAL DEVICE CONTROLLER WITH CAPACITOR FRAMING - A serviceable wearable cardiac treatment device for continuous extended use by an ambulatory patient includes a garment, a device controller, and an ingress-protective housing. The garment is configured to dispose therein a plurality of ECG sensing and therapy electrodes to monitor for and treat a cardiac arrhythmia in the patient. The device controller is configured to be in separable electrical communication with the plurality of ECG sensing and therapy electrodes and includes an impact-resistant energy core, and first and second circuit boards affixed to opposing sides of the impact-resistant energy core. The impact-resistant energy core includes a frame and at least one capacitor permanently bonded to the frame to form a unitary mass. The ingress-protective housing is configured to enable removal of the impact-resistant energy core and the first and second circuit boards during servicing. | 2021-05-06 |
20210128913 | TARGETING SMALL-DIAMETER AXONS FOR NEUROMODULATION - Small-diameter axons can be targeted for neuromodulation. A nerve modulating therapy can be configured to target the small diameter axons in a target area of a subject specifically. The nerve modulating therapy can be applied to the target area to modulate conduction in one or more small diameter axons within the target area to a greater degree than in large diameter axons within the target area. The nerve modulating therapy can be any therapy that affects an outer surface of the one or more small diameter axons (like a heat signal, a pressure wave, an optogenetic manipulation, and/or a pharmaceutical dosage). | 2021-05-06 |
20210128914 | SYSTEM AND METHOD FOR TREATING OBSTRUCTIVE SLEEP APNEA - One aspect of the present disclosure relates to a system for treating obstructive sleep apnea in a subject. The system can include a power source and a neuromuscular stimulator in electrical communications with the power source. The neuromuscular stimulator can include a controller and at least one electrode. The controller can be configured to receive certain power and stimulation parameters associated with a therapy signal from the power source. The at least one electrode can be configured to deliver the therapy signal to a target tissue associated with control of a posterior base of the tongue of the subject. | 2021-05-06 |
20210128915 | APPARATUS AND METHOD FOR STIMULATION OF BIOLOGICAL TISSUE - An apparatus for generating focused currents in biological tissue is provided. The apparatus comprises an electric source capable of generating an electric field across a region of tissue and means for altering the permittivity of the tissue relative to the electric field, whereby a displacement current is generated. The means for altering the permittivity may be a chemical source, optical source, mechanical source, thermal source, or electromagnetic source. | 2021-05-06 |
20210128916 | MONITORING AND TREATMENT SYSTEM FOR NEUROLOGICAL DISORDERS - The invention provides a system for inhibition or treatment of an aberrant neurological event in a subject. The system comprises: one or more detectors; a controller; and one or more stimulators of the vagus nerve. The invention also provides a method for treating and preventing epileptic seizures and the onset or pre-onset of epileptic seizures. The method includes the steps of: collecting signals from each of one or more detector indicating the presence of a repetitive movement; analyzing signals received from the one or more detector to determine the intensity of the stimulation of the auricular branch of the vagus nerve (ABVN) required to control, moderate or prevent current and future repetitive movements; and when required, signaling one or more stimulator to stimulate the ABVN so that the repetitive motion ceases using the determined stimulation intensities. | 2021-05-06 |
20210128917 | EEG CURVE FITTING TO SPECIFY STIMULATION PARAMETER - A method and system is provided for administering a Repetitive Transcranial Magnetic Stimulation (rTMS) or Transcranial Alternating Current Stimulation (tACS) at a pulse interval of is set equal to the period of a curve that best fits a section of a person's electroencephalogram (EEG) recorded before the pulse train. | 2021-05-06 |
20210128918 | COCHLEAR IMPLANT - A dichotic pulsatile and analog stimulation system, comprises a first cochlear implant device implanted in one ear of a patient; and a second cochlear implant device implanted in another ear of the patient; wherein the first cochlear implant device comprises a first speech processor configured to provide single channel analog stimulation to a first electrode array mounted to a cochlea of the one ear and the second cochlear implant device comprises a second speech processor configured to provide interleaved pulse stimulation to a second electrode array mounted to a cochlea of the other ear. | 2021-05-06 |
20210128919 | SYSTEM AND METHOD FOR EMBEDDING ELECTRONIC COMPONENTS WITHIN AN IMPLANT - A system and method for embedded electronics within a medical implant comprising: an implant body; a circuitry surface, containing at least one electronic component, wherein the circuitry surface is at least partially embedded within a defined cavity of the implant along at least one path; sheathing, comprising a protective structure, wherein the at least partially embedded portion of the circuitry surface is enclosed within the sheathing; electronic components connected to, or directly on, the circuitry surface, comprising a set of electrodes and an antenna; and wiring, connecting the circuitry surface and electronic components. The system and method may further include a casing, wherein the casing is a sealed structure directly connected to the implant body including a printed a circuit board (PCB) contained within the casing itself. | 2021-05-06 |
20210128920 | METHOD TO DESIGN TEMPORAL PATTERNS OF NERVOUS SYSTEM STIMULATION - The present invention relates to methods that enable one to design temporal patterns for the optimal stimulation of a nervous system, one or more nerve cells, or nervous tissue. In one embodiment, the present invention relates to methods to design improved stimulation patterns and/or genetic algorithms for the optimal stimulation of a nervous system, one or more nerve cells, or nervous tissue. In one embodiment, the present invention utilizes a model-based design to achieve a more optimal stimulation pattern for use in connection with a nervous system, one or more nerve cells, or nervous tissue (e.g., a human nervous system). In another embodiment, the model-based design of the present invention utilizes a systematic search method to identify parameters (e.g., design variables) that minimize a cost function (e.g., optimize the fitness of a particular design). In one instance, the system and method of the present invention is demonstrated via optimal temporal patterns of electrical stimulation for a nervous system, one or more nerve cells, or nervous tissue. | 2021-05-06 |
20210128921 | PAIN MANAGEMENT BASED ON EMOTIONAL EXPRESSION MEASUREMENTS - This document discusses, among other things, systems and methods for managing pain in a subject. A system may include one or more sensors configured to sense from the subject information corresponding to emotional reaction to pain, such as emotional expression. The emotional expression includes facial or vocal expression. A pain analyzer circuit may generate a pain score using signal metrics of facial or vocal expression extracted from the sensed information. The pain score may be output to a user or a process. The system may additionally include a neurostimulator that can adaptively control the delivery of pain therapy by automatically adjusting stimulation parameters based on the pain score. | 2021-05-06 |
20210128922 | Architectures for Sharing of Current Sources in an Implantable Medical Device - A group select matrix is added to an implantable stimulator device to allow current sources to be dedicated to particular groups of electrodes at a given time. The group select matrix can time multiplex the current sources to the different groups of electrodes to allow therapy pulses to be delivered at the various groups of electrodes in an interleaved fashion. Each of the groups of electrodes may be confined to a particular electrode array implantable at a particular non-overlapping location in a patient's body. A switch matrix can be used in conjunction with the group select matrix to provide further flexibility to couple the current sources to any of the electrodes. | 2021-05-06 |
20210128923 | NEUROMODULATION PROGRAMMING TOOLS FOR NEUROMODULATOR REPLACEMENT - A system may be used with a first neuromodulator of a first neuromodulator type and a second neuromodulator of a second neuromodulator type where the first neuromodulator is programmed with a first set of modulation parameter settings. The system may comprise an input configured for receiving the first set of modulation parameter settings for the first neuromodulator type, a processor configured to execute a programmed set of instructions to determine a second set of modulation parameter settings for the second neuromodulator type based on the first set of modulation parameter settings for the first neuromodulator type, and an output configured present the second set of modulation parameter settings for entering into a neuromodulator programmer. The neuromodulator programmer may be configured to program the second neuromodulator with the second set of modulation parameters. | 2021-05-06 |
20210128924 | SYSTEM AND METHOD FOR INDIRECT MEASUREMENT OF VENTRICULAR CONTRACTILITY - A system for monitoring and evaluating the ventricular contractility of a heart muscle includes a device for electrically stimulating the heart muscle of a patient, and an extracorporeal blood pressure sensor. A record, responsive to stimulated ventricular contractions, is created by the pressure sensor. The response record is then evaluated to identify a pressure/time, rate-change in arterial pressure (dp/dt) that results within the time duration of a ventricular contraction in a cardiac cycle. In turn, dp/dt is evaluated as an indicator of ventricular contractility and the health of the patient's heart muscle. | 2021-05-06 |
20210128925 | SYSTEMS AND METHODS FOR EVALUATING CARDIAC THERAPY - Systems and methods are described herein for evaluation and adjustment cardiac therapy. The systems and methods may initially evaluate a first pacing parameter while other pacing parameters are fixed to, for example, nominal values, and determine an effective setting for the first pacing parameter. Then, a second pacing parameter may be evaluated while the first pacing parameter is fixed to the previously-determined effective setting. Each evaluation may not test every possible setting for the pacing parameters, and instead, may utilize various processes to limit the settings to a subset of settings to test. | 2021-05-06 |
20210128926 | PERCUTANEOUS NERVE EVALUATION FOR SACRAL NEUROMODULATION - Practitioners who use sacral neuromodulation on a regular basis have sought ways to simplify the procedure and performing percutaneous nerve evaluations in the office setting have become increasingly more popular. However, many practitioners are limited by the lack of availability of fluoroscopy in the office setting and do not feel comfortable executing the procedure without it, for a variety of reasons. The disclosed system and method demonstrate an avenue to circumvent the lack of fluoroscopic guidance in the office setting enabling execution of percutaneous nerve evaluations successfully and efficiently. | 2021-05-06 |
20210128927 | Feedthrough Protective Cover - Implantable medical devices have a feedthrough from the device to the outside world to pass electrical current from electronics inside the implant to the patient or vice versa. A plurality of sensors and/or signal wires in a wire bundle must connect to the feedthrough and implant in living tissue in the patient. Chemical and physical forces work against the wire connections on the feedthrough. The several embodiments of the present invention include a biocompatible cap or top, shaped to attach onto the rim of the feedthrough device. One or more wire bundle ports are included on the cap. One or two layers of a sealant such as epoxy can be injected under the cap. A first layer of epoxy can rigidly protect the wire bonds while an elastomeric silicone can cover the epoxy for a flexible protector. Other embodiments include an implant housing with a recess for the feedthrough; a top can protect the recess. One or more sealants can cover the feedthrough in the recess. | 2021-05-06 |
20210128928 | System to Estimate the Location of a Spinal Cord Physiological Midline - Techniques for determining the location of a physiological midline are disclosed. A first technique evaluates the response to stimulation of spinal electrodes at peripheral electrodes on different sides of the body. In this technique, a spinal electrode's position relative to a physiological midline is determined based on a relationship between responses to its stimulation observed on different sides of the body. A second technique evaluates the response of spinal electrodes to stimulation of peripheral electrodes on different sides of the body. In this technique, a spinal electrode's position relative to a physiological midline is determined based on the different responses that it observes to stimulation on different sides of the body. | 2021-05-06 |
20210128929 | Microcatheter Structural Wire with Pacing Function - A microcatheter wire is configured for insertion into a human heart via a human artery. The microcatheter wire has a tube shaft formed from hollow flexible tubing, the tubing comprising an outer plastic layer, a middle conductive layer, and an inner plastic layer. A proximal opening on the tube shaft receives a slideable core. A conductive collar near the proximal end is an area of the tube shaft where the outer plastic layer has been removed and the conductive middle layer is exposed for connection to a pacemaker generator. A distal ring is formed unitarily with the tube shaft, and also has an outer plastic layer, a middle conductive layer, and an inner plastic layer. The distal ring has a plurality of conductive patches along its outer curve where the outer plastic layer has been removed to expose the middle conductive layer for contacting the human heart to allow heart pacing. | 2021-05-06 |
20210128930 | WEARABLE THERAPEUTIC DEVICE - A wearable therapeutic device is provided. The wearable therapeutic device includes a garment, and the garment includes an electrode and a conductive thread. A control unit is coupled to the conductive thread and identifies an electrical connection between a conductive surface of the electrode and the conductive thread, and an alarm module can provide information about the positioning of the electrode in the garment based on the electrical connection. | 2021-05-06 |
20210128931 | Muscle Optimization Device and Method - A system, device and method are provided for exposing a patient to therapeutic resonant frequency patterns (RFP) for therapy and treatment of a patient, for example, biological tissue such as muscle, tendon, ligament, and nerve tissue. The resonance frequencies originate from many bioactive substances, pharmaceuticals or other compounds, and key frequencies of the RFP of a compound can be replicated and then delivered to a patient using an electromagnetic catalyst to provide therapeutic benefits. RFPs can be imprinted in a separate device using a plasma imprinting device and method. This separate device can be actively excited by a delivery mechanism that uses electromagnetic or mechanical waves to interact with the device. The actively excited device transmits the RFPs or therapeutic resonant frequency patterns to the patient for similar enhancements and therapeutic benefits. | 2021-05-06 |
20210128932 | CHRONOTHERAPEUTIC TREATMENT PROFILING - An electromagnetic energy delivery system is configured to deliver energy in specific timing arrangements to improve an immune response. The electromagnetic energy delivery system may comprise a controlled electromagnetic energy source and an electromagnetic energy applicator, wherein the controlled electromagnetic energy source is configured to emit electromagnetic energy according to the specific timing arrangements as defined by a treatment profile which is configured so that the emitted electromagnetic energy stimulates and/or inhibits an immune response in a host when the emitted electromagnetic energy is delivered to the host via the electromagnetic energy applicator. A method of electromagnetic energy delivery,comprises delivering energy in specific timing arrangements to improve an immune response. | 2021-05-06 |
20210128933 | CAPSULE TYPE PHOTODYNAMIC THERAPY APPARATUS WITH ANCHOR - Disclosed herein is a capsule type photodynamic therapy apparatus. The apparatus has an anchor packaged with a silicone dome to anchor the apparatus to target tissue in a body by an endoscope, and includes a battery to communicate with an external device via human body communication in the silicone dome, and is repeatedly operated several times under the control of the external device to irradiate the target tissue with a therapeutic light source and thereby repeatedly treat the target tissue several times. | 2021-05-06 |
20210128934 | Eight-Trigrams Based Five-Color Phototherapy Device For Body Healing and Balance - Based on traditional Chinese medicine and ancient Eight-Trigram theory, a wearable five-color phototherapy device is invented for a unique painless, drug-free, non-invasive, and true green organic therapy by using light energy on some particular areas of a person's skin. There are multiple light-emitting components which is a number of light-emitting elements arranged in each of Eight-Trigram positions are designed on the bottom of this device. These multiple light-emitting components produce color of red or green or white or yellow or black or no color in each of Eight-Trigram positions. A software or App is developed to directly or remotely control and communicate with such device and provide the optimal solution for the five-color phototherapy. | 2021-05-06 |
20210128935 | PHOTOTHERAPEUTIC LIGHT FOR TREATMENT OF PATHOGENS - Methods and related devices for impinging light on tissue, for example within a body of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, stimulating enzymatic generation of nitric oxide to increase endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores of nitric oxide, and inducing an anti-inflammatory effect. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths. Devices and methods for light treatments are disclosed that provide light doses for inducing biological effects on various targeted pathogens and targeted tissues with increased efficacy and reduced cytotoxicity. | 2021-05-06 |
20210128936 | PHOTOTHERAPEUTIC LIGHT FOR TREATMENT OF PATHOGENS - Methods and related devices for impinging light on tissue, for example within a body of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, stimulating enzymatic generation of nitric oxide to increase endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores of nitric oxide, and inducing an anti-inflammatory effect. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths. Devices and methods for light treatments are disclosed that provide light doses for inducing biological effects on various targeted pathogens and targeted tissues with increased efficacy and reduced cytotoxicity. | 2021-05-06 |
20210128937 | PHOTOTHERAPEUTIC LIGHT FOR TREATMENT OF PATHOGENS - Methods and related devices for impinging light on tissue, for example within a body of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, stimulating enzymatic generation of nitric oxide to increase endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores of nitric oxide, and inducing an anti-inflammatory effect. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths. Devices and methods for light treatments are disclosed that provide light doses for inducing biological effects on various targeted pathogens and targeted tissues with increased efficacy and reduced cytotoxicity. | 2021-05-06 |
20210128938 | PHOTOTHERAPEUTIC LIGHT FOR TREATMENT OF PATHOGENS - Methods and related devices for impinging light on tissue, for example within a body of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, stimulating enzymatic generation of nitric oxide to increase endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores of nitric oxide, and inducing an anti-inflammatory effect. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths. Devices and methods for light treatments are disclosed that provide light doses for inducing biological effects on various targeted pathogens and targeted tissues with increased efficacy and reduced cytotoxicity. | 2021-05-06 |
20210128939 | LIGHT BASED SKIN TREATMENT DEVICE - A pulsed laser skin treatment device is for laser induced optical breakdown of hair or skin tissue. The device has a light exit window to be placed against a surface to be treated such as skin during use. A feedback system is used for determining a state of contact between the light exit window and the surface. To this end the feedback system is capable of detecting a feedback signal representative for the state of contact. If the feedback signal or the state of contact is such that the risk of skin surface or device damage by the device operation is too high, the user or the device has a way to interrupt the treatment or to reduce light output to reduce or eliminate this risk. | 2021-05-06 |
20210128940 | LIGHT-BASED TREATMENT DEVICES AND METHODS - A light treatment device includes a stacked structure for applying a light treatment to a patient's skin. The stacked structure includes a light source configured to emit treatment light, and a light diffusing layer. The light diffusing layer is configured to receive the emitted treatment light, diffuse the treatment light, and output diffused treatment light. | 2021-05-06 |
20210128941 | System and Methods of Unattended Treatment - In accordance with various aspects of the present teachings, systems and methods for applying treatment energy, e.g., electromagnetic radiation such as laser radiation in the visible and near infrared wavelengths, to body areas having bulges and fat deposits, loose skin, pain, acne and/or wounds. In some aspects, the systems and methods can enable relatively lengthy treatments to be performed by having the practitioner set-up and/or start the treatment, thereafter allowing the treatment to proceed safely and effectively without the continued presence of the practitioner. | 2021-05-06 |
20210128942 | CIRCADIAN RHYTHM ENTRAINMENT USING LIGHT THERAPY TO ENHANCE MEDICATION EFFECTIVENESS - A circadian rhythm entrainment platform can use medication circadian profiles that include mappings of medications to circadian rhythm disruptions and can make conversions of such circadian rhythm disruptions to administrations of light therapy to adjust for the disruptions. The circadian rhythm entrainment platform can specify how to entrain a patient's circadian rhythm using light therapy to compensate for or anticipate side effects of medications and for optimizing medication schedules for a patient's circadian rhythm so as to minimize side effects and increase medication effectiveness. The circadian rhythm entrainment platform can also gather information on the effects of medications on circadian rhythms and interact with patients, medical providers, and other providers in relation to light therapy. | 2021-05-06 |
20210128943 | SYSTEM AND METHOD FOR RADIATION THERAPY AND IMMOBILIZING DEVICE THEREOF - A radiation therapy system may be provided. The system may include a therapeutic apparatus. The therapeutic apparatus may include a radiation source for directing therapeutic radiation to at least one portion of a region of interest (ROI) of a subject, and an immobilizing device for immobilizing the subject. The system may obtain characteristics information of the subject. The system may preheat the immobilizing device according to a predictive model that processes the characteristics information of the subject. The system may send a control signal to the therapeutic apparatus for applying the therapeutic radiation to the at least one portion of the ROI immobilized by the preheated immobilizing device when the immobilizing device is preheated to a certain temperature. | 2021-05-06 |
20210128944 | SYSTEMS AND METHODS FOR DETERMINING FLOW PARAMETERS OF ADMINISTERED FLUID FROM RADIOEMBOLIZATION DELIVERY DEVICE - Methods and systems for determination of flow parameters of administered fluid from a radioembolization delivery device may include translationally moving a device delivery arm of the radioembolization delivery device in a translational direction, wherein the device delivery arm is coupled to a syringe holder such that move in the translational direction one of proximally or distally advances the syringe holder; sensing, via one or more pattern sensors, a corresponding movement of a pattern associated with the translational device delivery arm movement as a sensed pattern movement; generating, via the one or more pattern sensors, one or more output signals based on the sensed pattern movement; and generating, via a processor, a flow rate of the administered fluid, a flow amount of the administered fluid, and/or the translational direction of movement of the device delivery arm with respect to the syringe holder based on the one or more | 2021-05-06 |