| 18th week of 2016 patent applcation highlights part 39 |
| Patent application number | Title | Published |
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| 20160123900 | PROJECTION METHOD OF THREE-DIMENSIONAL IMAGING - A projection method of three-dimensional imaging includes the steps of respectively projecting a radiation field emitted from a radiation source with respect to one specific detector of a plurality of detectors and a three-dimensional sub-voxel onto two two-dimensional planes; rotating the specific detector to one specific axis of the two dimensional plane; performing a calculation for obtaining a sub-geometric factor corresponding to each specific detector and each voxel; and, finally, forming a geometric factor by combining each sub-geometric factor defined by each detector and each voxel. | 2016-05-05 |
| 20160123901 | INSPECTION SYSTEMS AND METHODS FOR SYNCHRONOUSLY POSITIONING RADIOACTIVE MATERIAL - A system and method for positioning radioactive material are provided. A scanning and imaging apparatus comprises a ray source configured to generate an X-ray and a detection device configured to receive an X-ray transmitted through an inspected object, wherein the ray source is configured to image the inspected object by emitting the X-ray to the inspected object. A radioactivity detector is configured to detect whether the inspected object comprises radioactive material synchronously with the process of scanning implemented by the scanning and imaging apparatus. In a case that the radioactive detector detects radioactive material, an actual position of the radioactive material in an X-ray image of the inspected object obtained by the scanning and imaging apparatus is marked in the image. The above solutions improve the accuracy of displaying the position of the radioactive source in the X-ray image. Further, inspection of radioactive material can be implemented while scanning an image. In this way, an error in the correspondence between inspection results of two systems when the two systems operate independently is avoided. | 2016-05-05 |
| 20160123902 | METHOD AND APPARATUS FOR IMPROVED SAMPLING RESOLUTION IN X-RAY IMAGING SYSTEMS - The present invention pertains to an apparatus and method for X-ray imaging wherein a radiation source comprising rows of discrete emissive locations can be positioned such that these rows are angularly offset relative to rows of sensing elements on a radiation sensor. A processor can process and allocate responses of the sensing elements in appropriate memory locations given the angular offset between source and sensor. This manner of allocation can include allocating the responses into data rows associated with unique positions along a direction of columns of discrete emissive locations on the source. Mapping coefficients can be determined that map allocated responses into an image plane. | 2016-05-05 |
| 20160123903 | METHOD OF INSPECTING A PART USING A MARKING TEMPLATE FOR RADIOGRAPHY - A method of inspecting a part is provided that includes the steps of aligning a contoured sheet having at least one surface that corresponds to at least one surface of the part, the contoured sheet having first portions and second portions, the first portions being radiodense and the second portions being radiolucent, and at least some of the second portions corresponding to internal features of the part. The part with the contoured sheet is exposed to x-rays to produce a first radiograph with markings that correspond to the first and second portions of the contoured sheet. | 2016-05-05 |
| 20160123904 | METHOD OF, AND APPARATUS FOR, MATERIAL CLASSIFICATION IN MULTI-ENERGY IMAGE DATA - An apparatus for processing multi-energy image data to separate at least two types of material comprises a classification unit, wherein the classification unit is configured to obtain a classification of pixels or voxels belonging to the types of material based on a threshold which is adaptively changed in dependence on multi-energy intensity information associated with the pixels or voxels. | 2016-05-05 |
| 20160123905 | Inspection of inconsistencies in and on semiconductor devices and structures - Disclosed embodiments are generally related to semiconductor device inspection. One such embodiment involves positioning a detector at a distance from a surface of the semiconductor device being inspected and applying an energy to the semiconductor device. In the disclosed embodiment, the detector receives back-scattered energy resulting from applying the energy to the semiconductor device and the resultant back-scattered energy is processed and analyzed to determine whether defects are beneath the surface of the semiconductor device. The magnitude of the applied energy and the distance between the detector and the surface of the semiconductor device are selected so as to allow back-scattered electrons returned from applying to be effectively received by the detector. | 2016-05-05 |
| 20160123906 | Method for Determining the Lithiation of Li-Ion Battery Electrodes - A method for determining an amount of lithium in a lithium-ion battery electrode sample includes a step of determining powder X-ray diffraction peaks of the lithium-ion battery electrode sample. The powder X-ray diffraction peaks of the lithium-ion battery electrode sample are compared with a set of lithium-containing samples having pre-determined lithium concentrations to determine the amount of lithium in the lithium-ion battery electrode sample. | 2016-05-05 |
| 20160123907 | Method for determining geometric relationships of crystal reciprocal vectors on two-dimensional planes obtained from single EBSD pattern - A method for determining geometric relationships of crystal reciprocal vectors on the two-dimensional planes obtained from an EBSD pattern includes steps of: geometrically correcting Kikuchi bands for obtaining the reciprocal vectors corresponding to the Kikuchi bands; selecting a set of reciprocal vectors which define a parallelogram with minimum area on the reciprocal plane as a two-dimensional basis for forming a grid, marking the basis; determining integer coordinates of other reciprocal vectors on the reciprocal plane relative to the basis, obtaining the deviations of the integer coordinates from the nearest grid nodes, marking the reciprocal vector with minimum deviation; fitting the length and the angel of the basis, redefining a new two-dimensional grid by the fitting result; repeating till all reciprocal vectors on the reciprocal plane are marked, wherein integer coordinates of the reciprocal vectors relative to the last two-dimensional basis now disclose the geometric relationships. | 2016-05-05 |
| 20160123908 | XRD SAMPLE HANDLING APPARATUS - Disclosed is a sample handling assembly facilitating a sample holding cell used for XRD analysis. The assembly holds the sample cell upright during sample loading and analysis phases. The sample handling assembly is vibrated, partly by a tuning fork, to allow the powder to flow into the sample cell. After the XRD analysis, a rotating arm holding the sample cell is rotated 180° to orient the sample cell completely upside down so that the sample can be emptied. Also disclosed are jets of air that are pulsed onto the sample cell, and/or into the sample cell funnel-tube assembly, to shake and clean the components. | 2016-05-05 |
| 20160123909 | MEASUREMENT OF SMALL FEATURES USING XRF - A method for X-ray measurement includes, in a calibration phase, scanning a first X-ray beam, having a first beam profile, across a feature of interest on a calibration sample and measuring first X-ray fluorescence (XRF) emitted from the feature and from background areas of the calibration sample surrounding the feature. Responsively to the first XRF and the first beam profile, a relative emission factor is computed. In a test phase, a second X-ray beam, having a second beam profile, different from the first beam profile, is directed to impinge on the feature of interest on a test sample and second XRF emitted from the test sample is measured in response to the second X-ray beam. A property of the feature of interest on the test sample is computed by applying the relative emission factor together with the second beam profile to the measured second XRF. | 2016-05-05 |
| 20160123910 | METHOD FOR QUANTITATIVE ANALYSIS OF HEAVY METALS - Disclosed is a method for quantitative analysis of heavy metals, particularly lead, arsenic, antimony or cadmium, in a liquid sample. Also disclosed is a method for quantitative analysis of heavy metals, particularly lead, arsenic, antimony or cadmium, in a powdery sample. | 2016-05-05 |
| 20160123911 | SYSTEMS AND METHODS FOR SELECTIVE SENSING AND SELECTIVE THERMAL HEATING USING NANOSTRUCTURES - Various methods for sensing and/or heating that utilize nanostructures or carbon structures, such as nanotubes, nanotube meshes, or graphene sheets, are disclosed. In some methods, at least a pair of contacts are electrically coupled with a given nanostructure or carbon structure to sense a change or to pass a current for heating. | 2016-05-05 |
| 20160123912 | Method For Evaluating Arc-Resistance Performance And Arc-Resistance Performance Evaluation Device - An arc-resistance performance evaluation device includes a plasma generator that generates plasma; and a stand on which a sheet-like test piece is placed so that the plasma generated in the plasma generator is irradiated on a front surface of said test piece, the stand includes a temperature measurement device that measures a temperature on a back surface of said test piece. | 2016-05-05 |
| 20160123913 | SYSTEMS AND METHODS OF SENSING AND/OR HEATING USING NANOSTRUCTURES - Various methods for sensing and/or heating that utilize nanostructures or carbon structures, such as nanotubes, nanotube meshes, or graphene sheets, are disclosed. In some methods, at least a pair of contacts are electrically coupled with a given nanostructure or carbon structure to sense a change or to pass a current for heating. | 2016-05-05 |
| 20160123914 | DETONATOR SYSTEM CONFIRMATION - A signal is injected into a wired series of detonators to obtain a reflected signal which represents a validated status of the system. The reflected signal is compared to a second reflected signal, generated in a similar way, some time later; to detect factors which affect the validated status of the system. | 2016-05-05 |
| 20160123915 | PHOTOELECTROCHEMICAL ASSAY APPARATUS FOR DETERMINING CHEMICAL OXYGEN DEMAND - The present disclosure discloses a chemical oxygen demand detection apparatus. In the apparatus, a working electrode, which is included TiO | 2016-05-05 |
| 20160123916 | Small Volume In Vitro Analyte Sensor - A sensor designed to determine the amount and concentration of analyte in a sample having a volume of less than about 1 μL. The sensor has a working electrode coated with a non-leachable redox mediator. The redox mediator acts as an electron transfer agent between the analyte and the electrode. In addition, a second electron transfer agent, such as an enzyme, can be added to facilitate the electrooxidation or electroreduction of the analyte. The redox mediator is typically a redox compound bound to a polymer. The preferred redox mediators are air-oxidizable. | 2016-05-05 |
| 20160123917 | Sensor and Method for Removing Interfering Substance - A technique is provided, wherein any influence, which would be otherwise exerted on a reaction of an objective substance caused by a reagent enzyme by an interfering substance contained in a specimen, is suppressed in relation to an electrochemical sensor for measuring the objective substance contained in the specimen. A sensor comprises a substrate; a detecting unit which is provided on the substrate and which detects an objective substance; a filter which covers the detecting unit, which permits permeation of the objective substance on one hand, and which regulates permeation of an interfering substance contained in a sample on the other hand; and removing unit which removes the interfering substance adhered to the filter. | 2016-05-05 |
| 20160123918 | Sensor and Method for Removing Interfering Substance - A technique is provided, wherein any influence, which would be otherwise exerted on a reaction of an objective substance caused by a reagent enzyme by an interfering substance contained in a specimen, is suppressed in relation to an electrochemical sensor for measuring the objective substance contained in the specimen. A sensor comprises a substrate; a detecting unit which is provided on the substrate and which detects an objective substance; a filter which covers the detecting unit, which permits permeation of the objective substance on one hand, and which regulates permeation of an interfering substance contained in a sample on the other hand; and removing unit which removes the interfering substance adhered to the filter. | 2016-05-05 |
| 20160123920 | NITROGEN OXIDE DECOMPOSITION MATERIAL AND USE THEREOF - The present teaching rekates to providing a NOx decomposition agent having an excellent NOx decomposition rate. The NOx decomposition agent containing a perovskite oxide represented by ABx-1MxO | 2016-05-05 |
| 20160123921 | MULTICHANNEL POTENTIOSTAT ANALYZER SYSTEM AND METHODS - The present disclosure outlines a device having a multi-channel potentiostat circuit and a microcontroller for controlling the multi-channel potentiostat circuit. The multi-channel potentiostat circuit includes a counter electrode, a reference electrode, and a first switch between the counter electrode and the reference electrode. The multi-channel potentiostat circuit also includes a plurality of measurement circuits coupled to respective second switches. The microcontroller can configured to provide a first signal to the multi-channel potentiostat circuit to control the first switch, wherein a state of the first switch changes an operating mode of the multi-channel potentiostat circuit. The microcontroller is also configured to provide a second signal to the multi-channel potentiostat circuit to control at least one of the second switches to couple at least one of the plurality of measurement circuits to a working electrode. | 2016-05-05 |
| 20160123922 | GAS SENSOR CONTROL APPARATUS - A sensor element of an A/F sensor AS has a solid electrolyte layer, a first electrode arranged on one side of the solid electrolyte layer so as to be exposed to the exhaust gas of an internal combustion engine, and a second electrode arranged on the other side of the solid electrolyte layer so as to face an atmospheric air chamber. The sensor element generates a sensor output according to the oxygen concentration in the exhaust gas. A microcomputer supplies oxygen to the first electrode side from the second electrode side via the solid electrolyte layer by applying a predetermined voltage between the pair of electrodes and of the sensor element. Moreover, the microcomputer determines a crack abnormality of the solid electrolyte layer based on electric current between the pair of electrodes which is generated with start of the oxygen supply. | 2016-05-05 |
| 20160123923 | EXPORTING MEASUREMENTS OF NANOPORE ARRAYS - A method of exporting measurements of a nanopore sensor on a nanopore based sequencing chip is disclosed. An electrical characteristic associated with the nanopore sensor is measured. The electrical characteristic associated with the nanopore sensor is processed. A summary for the electrical characteristic and one or more previous electrical characteristics is determined. The summary for the electrical characteristic and the one or more previous electrical characteristics are exported. Determining the summary includes determining that the electrical characteristic and at least a portion of the one or more previous electrical characteristics correspond to a base call event at the nanopore sensor. The summary represents the electrical characteristic and the at least a portion of the one or more previous electrical characteristics. | 2016-05-05 |
| 20160123924 | PARTICLE SIZE DISTRIBUTION MEASUREMENTS OF PARTICLES AND DROPLETS USING OPTICAL GEL ELECTROPHORESIS - A device for measuring size distributions of particles and droplets includes a gel electrophoresis component that has a gel chamber that is suitable to receive a gel in which at least one of particles or droplets propagate in a liquid medium during operation; an illumination source arranged to illuminate said at least one of particles or droplets such that the at least one of particles or droplets absorbs, scatters or emits light; an imaging device configured to obtain image data from the absorbed, scattered, or emitted light from the at least one of particles or droplets while the at least one of particles or droplets propagate through the gel; and a computing device configured to receive and process the image data to provide information concerning a size distribution of the at least one of particles or droplets. | 2016-05-05 |
| 20160123925 | MULTI-DIMENSIONAL ELECTROPHORESIS APPARATUS - An electrophoresis apparatus is generally disclosed for sequentially analyzing a single sample or multiple samples having one or more analytes in high or low concentrations. The apparatus comprises a relatively large-bore transport capillary which intersects with a plurality of small-bore separation capillaries and includes a valve system. Analyte concentrators, having antibody-specific (or related affinity) chemistries, are stationed at the respective intersections of the transport capillary and separation capillaries to bind one or more analytes of interest. The apparatus allows the performance of two or more dimensions for the optimal separation of analytes. The apparatus may also include a plurality of valves surrounding each of the analyte concentrators to localize each of the concentrators to improve the binding of one or more analytes of interest. | 2016-05-05 |
| 20160123926 | METHODS OF ISOLATING NUCLEIC ACIDS UNDER REDUCED DEGRADATION CONDITION - A method of isolating nucleic acids from a biological material, comprises applying the biological material on a substrate comprising one or more cell lysis reagents impregnated therein; applying a fluid to the biological material applied on the substrate; extracting the nucleic acids from the biological material applied on the substrate; and collecting the extracted nucleic acids in a substantially intact form, wherein the collected nucleic acid has a molecular weight greater than or equal to 20 kb. | 2016-05-05 |
| 20160123927 | Split-Ring Resonator Plasma Source - A miniaturized plasma source includes a stripline split-ring resonator. The split-ring resonator is sandwiched between two dielectric substrates and two metal ground planes. In order to make the plasma accessible from the outside of the ground planes, a hole is made through the gap between the ends of the split ring. The two ground planes act as an electromagnetic shield, protecting the split-ring resonator from electromagnetic interference due to changes in the electric or dielectric environment surrounding it. The miniaturized plasma source is particularly useful in optogalvanic spectroscopy applications. | 2016-05-05 |
| 20160123928 | EDDY CURRENT FLAW DETECTION DEVICE, EDDY CURRENT FLAW DETECTION METHOD, AND EDDY CURRENT FLAW DETECTION PROGRAM - There is provided an eddy current flaw detection technique capable of, even when inspecting an object having a narrow portion with a small curvature radius, recognizing detection sensitivity change due to change of attitude of a probe. | 2016-05-05 |
| 20160123929 | VEHICLE UREA TANK ASSOCIATED WITH A SENSING CHAMBER FOR ACOUSTIC QUALITY AND LEVEL SENSING - A device to measure a quality of a urea solution of a vehicle urea tank or of a urea solution coming from a tank, includes a chamber, at least one ultrasonic transceiver configured to vertically emit an ultrasonic wave in the chamber, and a deflector extending in the chamber above the transceiver. The chamber includes an inlet for filling the chamber with a urea solution so that a level of the urea solution in the chamber reaches at least the deflector. | 2016-05-05 |
| 20160123930 | POROUS RESONANT SENSORS - In a general aspect, an apparatus can include a porous, monolithic resonator having nanoscale pores defined therein. The apparatus can also include an adsorbent selective to a given analyte disposed on an exterior of the porous, monolithic resonator, the exterior of the porous, monolithic resonator including surfaces defining the nanoscale pores. | 2016-05-05 |
| 20160123931 | Apparatus And Method For Non-Intrusive Assessment Of Gas In Packages - A method and apparatus are disclosed for assessment of a sealed package. Light is emitted from a narrow-band laser source towards said package from outside of said package. An absorption signal of said light scattered in said package is measured, wherein said absorption is caused by said at least one gas when said light is scattered and travels in said sealed package. Measuring is made outside of said package, whereby said assessment is non-intrusive with regard to said package. It is determined if a deviation exists from a predetermined, expected gas composition and/or concentration of said at least one gas within said sealed package based on said measured absorption signal. Thus sealing of said package for said gas is detected. | 2016-05-05 |
| 20160123932 | METHOD FOR ULTRASOUND SCANNING OF A WELD BUILDUP - A method for scanning a weld buildup formed on a circumferential portion of a disc for a steam turbine. The method includes providing an ultrasound probe for generating at least one ultrasound beam sweep. The circumferential portion is scanned with a first beam sweep oriented in a first beam orientation to detect a first flaw type in the weld buildup. The circumferential portion is also scanned with a second beam sweep oriented in a second beam orientation to detect a second flaw type in the weld buildup. Further, the circumferential portion is scanned with a third beam sweep oriented in a third beam orientation to detect a third flaw type in the weld buildup. The method also includes rotating the disc about a disc axis during scanning of the circumferential portion and moving the first, second and third beam sweeps in a direction parallel to the disc axis during scanning. | 2016-05-05 |
| 20160123933 | NON-DESTRUCTIVE ULTRASONIC INSPECTION APPARATUS, SYSTEMS, AND METHODS - As described herein, a system for inspecting a component includes an ultrasonic inspection probe with a component surface interface, and a robotic device with an end effector coupled to the ultrasonic inspection probe. The robotic device is automatably controllable to move the ultrasonic inspection probe across a surface of the component. Additionally, the system includes an angle sensor subsystem coupled between the ultrasonic inspection probe and the end effector. The angle sensor subsystem is configured to operably detect an actual orientation of the end effector relative to a presently inspected portion of the surface of the component. The system includes a controller configured to receive orientation data from the angle sensor subsystem, the orientation data comprising the actual orientation of the end effector, compare the actual orientation to a desired orientation, and control the robotic device to adjust an orientation of the end effector to be in the desired orientation. | 2016-05-05 |
| 20160123934 | APPARATUSES, SYSTEMS, AND METHODS FOR INSPECTING A COMPONENT - Described herein is an apparatus for inspecting a component includes a first feature inspector with at least one wave transducer configured to inspect a first feature of the component. The first feature inspector further includes at least one displacement sensor configured to detect a displacement of the at least one wave transducer of the first feature inspector relative to the first feature of the component. The apparatus further includes a second feature inspector with at least one wave transducer configured to inspect a second feature of the component. The second feature inspector further includes at least one displacement sensor configured to detect a displacement of the at least one wave transducer of the second feature inspector relative to the second feature of the component. | 2016-05-05 |
| 20160123935 | SAMPLE ODOR TESTING DEVICE, TEST RETAINER USED THEREIN, AND SAMPLE ODOR EXAMINATION METHOD - The invention provides a sample odor testing device with which one sample is measured, and then, a next sample can be immediately measured. The sample odor testing device ( | 2016-05-05 |
| 20160123936 | Versatile Ambient Ionization-Based Interface for LC/MS - An apparatus ( | 2016-05-05 |
| 20160123937 | METHOD FOR EVALUATING PRETREATMENT OF COAT MATERIAL ON MICRO-PORE OF AUTOMOBILE BODY PANELS - A method for evaluating pretreatment of a coat material applied to a micro-pore of body panels of an automobile includes preparing a jig including a pair of steel plates, a spacer constituting the micro-pore between the steel plates, and a fixing means fixing the steel plates and the spacer outside the steel plates in order to fix the steel plates and the spacer while the spacer is inserted between the steel plates, inserting the spacer between the steel plates by setting the micro-pore of the jig and manufacturing an evaluating jig by using fixing means, forming a coat by applying the coat material to the micro-pore of the jig, and removing the jig and measuring and evaluating the weight of the formed coat. | 2016-05-05 |
| 20160123938 | PREDICTIVE ANALYSIS OF COMPLEX DATASETS AND SYSTEMS AND METHODS INCLUDING THE SAME - Predictive analysis of complex datasets and systems and methods including the same are disclosed herein. The methods include analyzing airborne particle count data from a cleanroom environment to predict a particle count fault condition within the cleanroom environment. The methods further include generating an airborne particle count data repository that includes particle counts within the cleanroom environment, analyzing the airborne particle count data to calculate a difference between a first rate of change and a second rate of change, and predicting the particle count fault condition responsive to the difference between the first rate of change and the second rate of change being outside a predetermined threshold range difference. The systems include computer readable storage media including computer-executable instructions that, when executed, direct a data analysis system to perform the methods. The systems also include a distributed cleanroom particle count monitoring system including a plurality of detection nodes. | 2016-05-05 |
| 20160123939 | APPARATUS AND METHOD FOR TESTING GAS METERS - An apparatus that is configured to test operation of a gas meter. The apparatus can include a process control member with operative circuitry that provides all functionality necessary to execute the test and to analyze the resulting data. This functionality includes data processing functions and a web server to allow communication between the apparatus and a remote device via a network. In one embodiment, the operative circuitry includes a first circuitry to regulate operation of a fluid moving unit that provides fluid to a meter-under-test. The operative circuitry can also include a second circuitry to collect data from one or more sensors disposed on the meter-under-test. The operative circuitry can also have a third circuitry to perform various operations necessary to calculate, in one example, a value for an operative characteristic that relates to the accuracy of the meter-under-test. | 2016-05-05 |
| 20160123940 | RELATIVE HUMIDITY SATURATED SALT GENERATOR - Disclosed RH generators include a lower component having a first chamber and an upper component including a second chamber, the upper component being coupled to the lower component to couple the first chamber to the second chamber. The first chamber is configured to contain liquid water and generate 100% RH, while the second chamber is configured to contain salt and generate a second RH less than 100% RH. A first membrane is positioned between the first chamber and the second chamber to allow water vapor to pass between the first and second chambers while blocking liquid water, the salt, and other larger molecules. The upper component is couplable to an RH probe with a second membrane separating the second chamber from the RH probe, which allows water vapor to pass between the second chamber and the RH probe to expose the RH probe to the second RH. | 2016-05-05 |
| 20160123941 | REMOTE CHEMICAL DETECTION AND IDENTIFICATION SYSTEMS AND METHODS - A system for detecting the release of a chemical substance includes a release device configured to release a chemical substance into a surrounding environment based on receipt of a control signal; a signaling device configured to transmit the control signal to the release device; and a sensor device configured to detect the chemical substance in the surrounding environment based on an analysis of the surrounding environment. | 2016-05-05 |
| 20160123942 | GAS CURTAIN AT INLET FOR TRACE DETECTORS - The present disclosure is directed to methods and systems for creating a gas curtain inlet for a detector of a substance of interest. The methods and systems include introducing a carrier gas into an inlet to block out atmospheric air without having to make the inlet a sealed system. | 2016-05-05 |
| 20160123943 | GAS RECOGNITION METHOD BASED ON COMPRESSIVE SENSING THEORY - A gas recognition method based on a compressive sensing theory. The method comprises: collecting compressed data in an under-sampling manner; performing a reconstruction on the collected compressed data to obtain reconstructed data; training a back-propagation neural network by using the reconstructed data and storing the trained back-propagation neural network; inputting data under test into the trained back-propagation neural network, such that the trained back-propagation neural network performs a recognition on the data under test to realize qualitative recognition of gas. The method solves the problem in transmission and storage of large amount of data and the problem of imprecise recognition in current gas detection, and achieves the object that a precise qualitative recognition is achieved by using a reduced amount of data. | 2016-05-05 |
| 20160123944 | METHOD FOR MANUFACTURING NO2 GAS SENSOR FOR DETECTION AT ROOM TEMPERATURE - A method for manufacturing an NO | 2016-05-05 |
| 20160123945 | NOx SENSOR CALIBRATION AND APPLICATION IN LEAN NOx TRAP AFTERTREAT SYSTEMS - An aftertreatment system utilizes chemical reactions to treat an exhaust gas flow. A system for aftertreatment of the exhaust gas flow includes a NOx sensor configured to monitor within the exhaust gas flow one of a lambda value and a NOx concentration value and a computerized processor device configured to calibrate the monitored value for presence of one of NH | 2016-05-05 |
| 20160123946 | SYSTEM FOR ANALYZING MERCURY - An analyzer system ( | 2016-05-05 |
| 20160123947 | Ammonia Nanosensors, and Environmental Control System - Embodiments of nanoelectronic sensors are described, including sensors for detecting analytes such ammonia. An environmental control system employing nanoelectronic sensors is described. A personnel safety system configured as a disposable badge employing nanoelectronic sensors is described. A method of dynamic sampling and exposure of a sensor providing a number of operational advantages is described. | 2016-05-05 |
| 20160123948 | Method For Improving Animal Food Product Quality - The invention relates to food animal care and husbandry. Disclosed is a novel method of evaluating the production characteristics of a food animal or group of food animals, is provided. More specifically, the invention relates to a method of determining the overall oxidative status of a sample taken from a food animal by measuring the oxidation-reduction potential (ORP) of the sample. The measured ORP value of the sample is then used to review the animal's environment and, if necessary, adjust the environment of the animal. In order to improve the production characteristics of food products from the animal. Also provided is a method of using the ORP value of a food product to determine production characteristics of the food product. | 2016-05-05 |
| 20160123949 | Measuring Phosphorus in Wastewater Using a Self-Organizing RBF Neural Network - In various implementations, methods and systems are designed for predicting effluent total phosphorus (TP) concentrations in an urban wastewater treatment process (WWTP). To improve efficiency of TP prediction, a particle swarm optimization self-organizing radial basis function (PSO-SORBF) neural network may be established. Implementations may adjust structures and parameters associated with the neural network to train the neural network. The implementations may predict the effluent TP concentrations with reasonably accuracy and allow timely measurement of the effluent TP concentrations. The implementations may further collect online information related to the estimated effluent TP concentrations. This may improve the quality of monitoring processes and enhance management of WWTP. | 2016-05-05 |
| 20160123950 | SENSOR SYSTEM AND METHOD FOR SENSING CHLORINE CONCENTRATION - Certain embodiments include a sensor system for measuring chlorine concentration in water. The sensor system can have a manifold including one or more flow passages for receiving fluid flow. The sensor system can have a probe for measuring chlorine concentration in fluid communication with a flow passage of the one or more flow passages of the manifold. The probe can have a probe body oriented to direct incoming fluid from one or more flow passages of the manifold toward an end of the probe body. The probe can have a plurality of flutes defined on an outer surface of the probe body. The flutes can be shaped and oriented to direct fluid from the end proximal to the electrodes, back toward the one or more flow passages of the manifold. | 2016-05-05 |
| 20160123951 | Software and Method of Calculation of Carbon Concentration Distribution - A method of calculation of carbon concentration distribution in a member as a result of carburizing includes calculating n-dimensional carbon diffusion of the member, determining calculation region for which (n+1)-dimensional carbon diffusion of the member is calculated, determining a boundary condition of the (n+1)-dimensional calculation region, and calculating the (n+1)-dimensional carbon diffusion by applying the n-dimensional calculation result to the boundary condition of the (n+1)-dimensional calculation region. Further, software for calculating carbon concentration distribution in a member as a result of carburizing includes outputting a calculation result by calculating n-dimensional carbon diffusion of the member, and outputting a calculation result by calculating (n+1)-dimensional carbon diffusion of the member by applying the n-dimensional calculation result to a boundary condition of a calculation region for which the (n+1)-dimensional carbon diffusion of the member is calculated. | 2016-05-05 |
| 20160123952 | Systems, Buffer Solutions, and Methods for Predicting Acidic Amendment Requirements in Soils - A method and system for testing soil includes wetting a selected soil sample to obtain a soil solution and measuring an initial pH of the soil solution. A buffer solution is then applied to the soil solution to displace alkaline anions from soil colloids of the soil solution with a displacement agent and to neutralize the alkaline anions with a neutralization agent in a buffer having a buffer pH of between 4.38 and 4.42. A resultant pH of the soil solution is then measured. A target pH for the soil sample is selected, and using mathematical relationships of the disclosure, an acidic amendment recommendation is obtained as a function of the initial pH, the resultant pH, and the target pH. | 2016-05-05 |
| 20160123953 | Evaluating Reservoir Oil Biodegradation - Upper and lower asphaltene weight fractions of fluid proximate ends of an oil column are obtained based on measured OD. Upper and lower maltene partial densities are obtained based on the asphaltene weight fractions. A maltene partial density distribution is obtained utilizing the maltene partial densities and a predetermined diffusion model. An asphaltene partial density distribution is obtained based on the maltene partial density distribution and an estimated mass density gradient. An asphaltene weight percentage is obtained based on the asphaltene partial density distribution and the mass density gradient. The asphaltene weight percentage distribution is converted to an OD distribution utilizing a predetermined correlation. An optimization then reduces differences between the OD distribution and the measured OD data to within a predetermined range to refine a biodegradation time of the predetermined diffusion model. A viscosity distribution may be obtained based on the optimized OD distribution. | 2016-05-05 |
| 20160123954 | EJECTION STRUCTURE AND CONNECTOR WITH EJECTION MECHANISM - An ejection structure includes a connector and an ejection element. The connector includes an opening and an ejection guiding groove for ejecting. The opening is received a biosensor test strip. The ejection guiding groove is disposed on a side of the connector and a front end of the guiding groove is communicating with the opening for receiving the biosensor test strip. The ejection element is assembled in the ejection guiding groove and comprises an actuating part used for contacting the biosensor test strip then ejecting the biosensor test strip along the ejection guiding groove from a rear end to the front end. Therefore, it omits extra assembled elements and simplifies the ejection structure so as to enhance the smoothness of the ejection mechanism. | 2016-05-05 |
| 20160123955 | SYSTEMS AND METHODS FOR AN EQUILIBRIUM WET BATH - A wet standard calibration system which utilizes a heat conducting foam with the liquid therein to serve as a primary heating device to avoid the need to include mechanical agitation. The system is particularly useful for generating a vapor comprising water and ethanol which can be used for the calibration of breath alcohol testers. | 2016-05-05 |
| 20160123956 | MODIFIED MEMBRANE SPANNING PROTEINS AND METHODS FOR THE PREPARATION AND USE THEREOF - In accordance with the present invention, there are provided functionally modulated tool receptors which are useful for drug discovery and development. In certain aspects and embodiments as described herein, a sophisticated and powerful approach has been designed that allows the rapid development of enhanced receptors, while simultaneously exploring millions of possibilities for improved properties with respect to such properties as protein expression, homogeneity, stabilization, conformational and activation pathway selectivity, antigenicity, immunogenicity, and the like. Indeed, the new methodology described herein represents a breakthrough by leveraging a full range of combinatorial amino acid replacements, in multiple positions simultaneously, in order to generate modified membrane-spanning proteins. | 2016-05-05 |
| 20160123957 | Visualization of P-TEFb by Fluorescence Complementation - Provided herein is a novel assay for the quantification of P-TEFb activation in living cells. The invention, in one embodiment, comprises cells which express P-TEFb and a P-TEFb-phosphorylated or P-TEFb-binding species, for example the C terminal domain of RNA polymerase II. Each of the P-TEFb and P-TEFb-phosphorylated or P-TEFb-binding species comprises a complementary signal moiety, for example complementary fragments of a fluorescent protein, such that when the P-TEFb interacts with the P-TEFb-phosphorylated or P-TEFb-binding species, the signal moieties are in sufficiently close proximity to generate a detectable signal. | 2016-05-05 |
| 20160123958 | APPARATUS AND METHODS FOR CONDUCTING ASSAYS AND HIGH THROUGHPUT SCREENING - The present invention provides microfluidic devices and methods for using the same. In particular, microfluidic devices of the present invention are useful in conducting a variety of assays and high throughput screening. Microfluidic devices of the present invention include elastomeric components and comprise a main flow channel; a plurality of branch flow channels; a plurality of control channels; and a plurality of valves. Preferably, each of the valves comprises one of the control channels and an elastomeric segment that is deflectable into or retractable from the main or branch flow channel upon which the valve operates in response to an actuation force applied to the control channel. | 2016-05-05 |
| 20160123959 | METHODS AND MATERIALS USING SIGNALING PROBES - The present invention relates to methods of isolating cells, generating cell lines, and detecting RNAs in cells using signaling probes that produce a signal upon hybridization to a target sequence. Other methods that utilize the signaling probe include methods of detecting or quantifying the effect of an agent on RNAs in a cell, methods of quantifying the level of RNA expression, methods for identifying genetic recombinational events in living cells and methods of generating a transgenic animal using the isolated cells. The invention also provides protease probes. Signaling probes and protease probes that form stem-loop structures, three-arm junction structures, and dumbbell structures are provided. | 2016-05-05 |
| 20160123960 | METHOD FOR PREPARING THREE-DIMENSIONAL, ORGANOTYPIC CELL CULTURES AND USES THEREOF - The present invention is directed to methods for generating isolated, unencapsulated, three-dimensional, cell culture products comprising a naturally-derived cell matrix distributed throughout the product and having dimensions suitable for use in in vitro applications including histological applications and imaging. | 2016-05-05 |
| 20160123961 | METHOD FOR MEASURING CELL-TO-CELL TRANSMISSION OF ALPHA-SYNUCLEIN AGGREGATES USING BIMOLECULAR FLUORESCENCE COMPLEMENTATION SYSTEM AND METHOD FOR SCREENING A SUBSTANCE FOR PREVENTING OR TREATING NEURODEGENERATIVE DISEASE USING THE SAME - The present disclosure relates to dual-cell model and | 2016-05-05 |
| 20160123962 | IL-34 RECEPTOR ASSAYS AND USES THEREOF - Methods are disclosed for identifying activators and inhibitors of actions of interleukin-34 (IL-34) that are independent of the colony stimulating factor-1 (CSF-1) receptor (CSF-1R) and play a role in development, homeostasis and disease. | 2016-05-05 |
| 20160123963 | METHOD FOR DETECTING CHEMICAL SUBSTANCES IN SAMPLES OF MATERIAL THAT CAN BE TAKEN FROM A SUBJECT, IN PARTICULAR FOR DETECTING EMBRYOTOXIC FACTORS - A method for detecting chemical substances in samples of material that can be taken from a subject, comprising a step of preparing a sample of a substance coming from a donor organism; a step of associating with said sample of a substance a control element suitable for verifying a presence of at least one active agent in the sample of the substance and a step of verifying the presence or absence of the active agent based on a change in state in said control element; the control element comprising at least one living organism having the ability to nourish itself autonomously through temporary organs associated with the living organism itself and able to supply nutritive substances to the latter without taking said nutritive substances from an outside environment. | 2016-05-05 |
| 20160123964 | METHODS FOR STRATIFYING NON-RESPONDERS TO THERAPIES THAT BLOCK PD1/PDL1 AXIS - A method of analyzing a biological sample from a subject that has a tumor or cancer, comprising: determining, for target cells having a phenotype of interest spatial resolution of the target cells, density of the spatially resolved target cells in the sample; and proximity between spatially resolved target cells of interest in the sample; and determining an overall score based at least in part on the preceding parameters. A method for identifying a patient as a responder to single agent anti-PD-1 or anti-PD-L1 therapy is provided. Similar methods are provided for detecting adaptive immune resistance, the presence of cancer in a patient sample, determining efficacy of cancer therapy, and determining response to and monitoring the efficacy of cancer therapy. | 2016-05-05 |
| 20160123965 | REAGENTS, METHODS AND DEVICES TO PREVENT AGGREGATION IN PARTICLE BASED TESTS FOR THE DETECTION OF MULTIMERIC TARGET MOLECULES - The present invention relates to a method for preventing aggregation of detection particles in a test for detecting a multi-epitope target analyte comprising two or more similar or identical epitopes in a sample and/or for determining the concentration of the multi-epitope target analyte in a sample wherein the method comprises the step of applying a first capture entity which can specifically bind to at least one epitope on the multi-epitope analyte, characterized in that the first capture entity blocks the at least one epitope from binding to a detection particle. The invention further relates to a method wherein the detection of the multi-epitope target analyte comprises the use of a second capture entity, which can specifically bind to the same or similar epitope of the multi-epitope target analyte as the first capture entity. Also envisaged is a method for the detection of said multi-epitope target analyte, the performance of the method in a system comprising a sensor surface and the use of a first capture entity to block the at least one epitope from binding to a detection particle such as a magnetic detection particle. | 2016-05-05 |
| 20160123966 | CYCLIC-DI-AMP SPECIFIC DETECTION - The present disclosure provides a simple yet fast, cost effective, reliable method for the detection and quantification of cyclic-di-adenosine monophosphate (c-di-AMP) by measuring c-di-AMP binding to a c-di-AMP-binding protein (CabP). A sample is contacted with CabP in the presence of biotin-labeled c-di-AMP. Once binding has reached equilibrium, unbound c-di-AMP is removed and the CabP-bound c-di-AMP is contacted with an enzyme-conjugated biotin-binding protein and a chromogenic substrate to generate a detectable signal. The signal generated correlates to the amount of unlabeled c-di-AMP in the sample. | 2016-05-05 |
| 20160123967 | DETECTION OF PATHOGENS USING UNMODIFIED METAL NANOPARTICLES - The present disclosure relates to a method for the direct detection of pathogen in a sample using unmodified metallic nanoparticles, such as gold nanoparticles. The method may employ colorimetric detection. The combination of unmodified metallic nanoparticles and colorimetric detection provides a method that is simple, rapid, and economical compared to prior art methods that require modified nanoparticles or expensive detection equipment. The method does not require labeling of the target pathogen and is capable of detecting a broad spectrum of pathogens. | 2016-05-05 |
| 20160123968 | DEVICE AND METHOD FOR DETECTING AN ANALYTE - A detection device detects an analyte that may be contained in a specimen. The detection device includes a plurality of gold nanoparticles, an optical trapping light source, an illumination light source, an objective lens, an image pick-up device, and a computation unit. The plurality of gold nanoparticles are each modified with a probe DNA allowing the analyte to specifically adhere thereto. The optical trapping light source emits polarized light for assembling the plurality of gold nanoparticles together. The objective lens focuses and introduces the polarized light into a liquid containing a specimen and the plurality of gold nanoparticles. The image pick-up device receives light from the liquid. The computation unit detects an analyte based on a signal received from the image pick-up device. | 2016-05-05 |
| 20160123969 | METHODS, MATERIALS, AND KITS FOR COVALENTLY ASSOCIATING MOLECULAR SPECIES WITH A SURFACE OF AN OBJECT - Described herein are methods, materials, and kits for covalently associating molecular species with a surface of an object. The subject matter of the present invention involves, in some cases, interrelated products, alternative solutions to a particular problem, and/or a plurality of different uses of one or more systems and/or articles. In some aspects, methods are provided. In some embodiments, a method for covalently associating a molecular species with a surface comprises exposing an object with a surface comprising a plurality of functional groups to a first type of molecular species. | 2016-05-05 |
| 20160123970 | MOLECULAR CYTOMETRY - The invention relates to methods and devices for molecular cytometry. The molecular cytometer is for use in the analysis of molecular tag labeled particles. In the molecular cytometer, volatile molecular tags attached to the particles, such as cells, are released as groups of molecular tags and ionized by the method of soft ionization to produce corresponding groups of molecular ions. The molecular cytometer has two detectors, one to detect the presence of the groups of molecular ions and the other to detect mobility separated molecular ions. The mobility separated molecular ions are synchronized to correspond with the groups of molecular ions. | 2016-05-05 |
| 20160123971 | NUCLEAR MAGNETIC RESONANCE APPARATUS AND METHODS - A nuclear magnetic resonance (NMR) apparatus includes at least one magnet configured to induce a static magnetic field in a sample of material to be analyzed. At least one radio frequency antenna is configured to induce a radio frequency magnetic field in the sample of material to be analyzed. The sample chamber is disposed in a substantially longitudinally continuous sample holder separated into discrete sample chambers. Each sample chamber has an internal opening dimension such that substantially all of each sample is affected by surface contact phenomena with an internal wall of each sample chamber. | 2016-05-05 |
| 20160123972 | FLUORESCENCE IMMUNOASSAY SENSOR CHIP AND FLUORESCENCE IMMUNOASSAY METHOD - Provided is a fluorescence immunoassay sensor chip and a fluorescence immunoassay method, which are capable of measuring, at the same time, a marker requiring high sensitivity due to its low content in a sample solution and a marker not requiring high sensitivity due to its high content in a sample solution. The fluorescence immunoassay sensor chip for use in fluorescence immunoassay for detecting and measuring markers contained in a sample solution includes: a dielectric member; a metal thin film formed on part of a main surface of the dielectric member; a first sensor part formed in a predetermined position on the metal thin film; and a second sensor part directly formed in a predetermined position on the dielectric member, wherein a ligand immobilized in the first sensor part and a ligand immobilized in the second sensor part capture different types of markers. | 2016-05-05 |
| 20160123973 | MULTIMODAL BIOSENSOR - Multimodal biosensor devices are disclosed. A device may include at least two sensors selected from: (i) a nanomechanical resonator; (ii) plasmonic nanodisk antennae; and (iii) a field effect transistor. The biosensor device is capable of transducing the adsorption of biomolecules onto the biosensor device into optical, electrical and/or mechanical signals. | 2016-05-05 |
| 20160123974 | Immunochromatographic Diagnosis Kit - Provided is an immunochromatographic diagnostic kit which renders prompt diagnosis possible, has high analysis sensitivity, and gives test results with excellent reproducibility. The immunochromatographic diagnostic kit includes: a conjugate pad that contains a conjugate containing chromogenic particles which have an average particle diameter of 100-1,000 nm and attain a color intensity of 1.0-10.0, 10-90 wt % of the particles being derived from cellulose and 90-10 wt % of the particles being derived from a colorant; and a sample pad for an in vitro diagnostic reagent, the sample pad being constituted of nonwoven fabric that has a basis weight of 10-150 g/m | 2016-05-05 |
| 20160123975 | Mesh Microfluidic Mixing Chamber - This document provides devices, systems, and methods for detecting pathogens in a biological sample. In some cases, the devices, systems, and methods include a microfluidic device, which includes a biological sample inlet in fluid communication with at least a first microfluidic chamber. The first microfluidic chamber holds a fibrous matrix. The fibrous matrix can carrying anticoagulant and target capture agents within the fibrous matrix. In some cases, the fibrous matrix can be a nonwoven sheet, which can entangle and retain particles bonded to the target capture agents. When in use, a biological sample is introduced into a microfluidic device to flow through the fibrous matrix to mix with the anticoagulant and contact target capture agents. The target capture agents can either remain in the fibrous matrix or flow to a target capture agent chamber. A lysis agent can be delivered through microfluidic chambers including the target capture agent and any captured targets to lyse the target and produce lysate, which can be analyzed to detect a presence of the target in the biological sample. | 2016-05-05 |
| 20160123976 | MULTIPLE HYBRID IMMUNOASSAY - The invention relates to compositions and methods for the immunoassay of an analyte of interest. The analyte is detected in an immunoassay using three or more antibodies, where in each antibody specifically binds to a different epitope on the analyte. When the analyte of interest in a clinical marker for an acute disease, the detection of the analyte by immunoassay is a diagnosis of the occurrence of the disease. | 2016-05-05 |
| 20160123977 | Assay Device With Shared Zones - Disclosed is an assay device for determining the presence and/or extent of one or more analytes in liquid sample containing a) first and second assays each comprising a flow-path having a detection zone for immobilising a labelled binding reagent, wherein detection of a labelled binding reagent at one or both detection zones is indicative of the presence and/or extent of one or more analytes; b) a shared reference zone; c) one or more light sources to illuminate the detection zones and the reference zone; d) one or more photodetectors to detect light from the detection zones and the reference zone, which photodetector/s generate a signal, the magnitude of which signal is related to the amount of light detected; and e) signal processing means for processing signals from the photodetector/s. | 2016-05-05 |
| 20160123978 | BIOCHIP, ANTIGEN BOUQUET, OPTICAL READER AND METHOD FOR DETECTING AND MONITORING DISEASES - The present invention comprises a biochip with specifically-designed configuration and microfluidic properties that increases the speed and effectiveness of the whole process of detection and monitoring diseases. This biochip is to be read in a specifically adapted optical reader for which an algorithm was developed and implemented to provide faster and more selective results, with a revealing method using quantum dots. The present invention is applicable to medical and diagnostic technical fields. | 2016-05-05 |
| 20160123979 | BIOMARKERS FOR EARLY DIAGNOSIS AND DIFFERENTIATION OF MYCOBACTERIAL INFECTION - Mycobacterial-specific biomarkers and methods of using such biomarkers for diagnosis of mycobacterial infection in a mammal are disclosed. | 2016-05-05 |
| 20160123980 | MULTICOLOR FLOW CYTOMETRY METHOD FOR IDENTIFYING A POPULATION OF CELLS, IN PARTICULAR MESENCHYMAL STEM CELLS - This invention is in the field of the identification and even isolation of mesenchymal stem cells (MSCs) and other cell types by means of differential specific fluorescence activated cell sorting (FACS). | 2016-05-05 |
| 20160123981 | A METHOD OF DETERMINING VIRUS REMOVAL FROM A SAMPLE CONTAINING A TARGET PROTEIN USING ACTIVATED CARBON - The present invention provides methods for determining whether activated carbon can be used for removing viruses or a certain virus from a sample containing a target protein. | 2016-05-05 |
| 20160123982 | METHODS FOR ASSAYING JAK2 ACTIVITY IN RED BLOOD CELLS AND USES THEREOF - The present invention relates to methods for assaying JAK2 activity in a red blood cell. The present invention also relates to methods for diagnosing myeloproliferative neoplasm. | 2016-05-05 |
| 20160123983 | HCV ANTIGEN-ANTIBODY COMBINATION ASSAY AND METHODS AND COMPOSITIONS FOR USE THEREIN - The present invention generally relates to combination immunoassays, reagents and kits for simultaneous detection of HCV antigens and anti-HCV antibodies in a test sample. | 2016-05-05 |
| 20160123984 | DRUG SELECTION FOR BREAST CANCER THERAPY USING ANTIBODY-BASED ARRAYS - The present invention provides compositions and methods for detecting the activation states of components of signal transduction pathways in tumor cells. Information on the activation states of components of signal transduction pathways derived from use of the invention can be used for cancer diagnosis, prognosis, and in the design of cancer treatments. | 2016-05-05 |
| 20160123985 | HEMATOPOIETIC CELL PHENOTYPING USING CIRCULATING CELL-FREE MARKERS - The present invention provides methods of classifying cluster of differentiation (CD) marker phenotype for hematopoietic cancer cells using multiple circulating cell-free CD markers in bodily fluid. In other aspects, treatment and disease progression of particular hematopoietic cancers can be monitored by measuring the levels of CD and other markers in bodily fluids of a patient. | 2016-05-05 |
| 20160123986 | METHOD FOR DIAGNOSING CANCER USING SECRETED RIBOSOMAL PROTEIN S3 - A method for diagnosing cancer using secreted ribosomal protein S3 (rpS3) is described, and more particularly, a method for diagnosing cancer or cancer metastasis using ribosomal protein S3 (rpS3) that is expressed in and secreted from cancer cells. Measuring the amount of extracellularly secreted rpS3 protein according to the present disclosure is highly useful for diagnosing cancer or cancer metastasis in a rapid and convenient manner using a biological sample such as blood. | 2016-05-05 |
| 20160123987 | ASSAY METHOD USING ENCODED PARTICLE-BASED PLATFORM - Provided is an assay method using an encoded particle-based platform. In the assay method, first, a plurality of encoded particles having codes distinguishable from one another according to kinds of included target materials are prepared. The plurality of encoded particles are provided onto a plate including a plurality of wells by pipetting, and disposed in the plurality of wells by a self-assembly method. An analyte is provided into the plurality of wells. The codes of the plurality of encoded particles disposed in the plurality of wells are decoded. The target materials of the plurality of encoded particles are released to cause a reaction between the target materials and the analyte. | 2016-05-05 |
| 20160123988 | METHOD OF TRACELESS LABELING GLYCOPROTEINS ON SURFACE AND APPLICATION THEREOF - The present invention relates to a method of traceless labeling glycoproteins on a surface and an application thereof. A test glycoprotein can be immobilized on a surface using a BA-tosyl probe and the BA-tosyl probe is then released using a releasing agent, so as to expose a glycan residue of the test glycoprotein. The exposed glycan residue of the test glycoprotein can be detected without altering native glycan structures. Moreover, the present invention further provides a detection kit of traceless labeling glycoproteins on a surface in the study of glycoprotein-protein interactions, which is suitable for using the aforementioned method. | 2016-05-05 |
| 20160123989 | METHODS AND KITS OF DETERMINING WHETHER A SUBJECT IS SUSCEPTIBLE TO HAVE A HYPER-AGGRESSIVE BEHAVIOUR - The present invention relates to methods and kits of determining whether a subject is susceptible to have a hyper-aggressive behaviour. In particular, the present invention relates to a method for determining whether a subject is susceptible to have a hyper-aggressive behaviour comprising the steps consisting of i) isolating the auto antibodies that bind to adrenocorticotropic hormone (ACTH) from a blood sample obtained from the subject, ii) determining the affinity of the isolated autoantibodies iii) comparing the affinity determined at step ii) with a predetermined reference value and iv) concluding that the subject is susceptible to have a hyper-aggressive behaviour when the affinity determined at step ii) is higher than the predetermined reference value. | 2016-05-05 |
| 20160123990 | AAV VECTOR AND ASSAY FOR ANTI-AAV (ADENO-ASSOCIATED VIRUS) NEUTRALIZING ANTIBODIES - Virus vectors, virus particles, and methods and uses of screening for, detecting, analyzing and determining amounts of virus antibody, or neutralizing antibody activity of samples are provided. Such virus vectors, virus particles, and methods and uses are applicable to a broad range of virus types, such as lentiviruses, adenovirus, and adeno-associated virus (AAV) serotypes. Methods and uses include virus antibody screening, such as anti-virus immunoglobulins screened for, detected, analyzed and amounts determined | 2016-05-05 |
| 20160123991 | Method for Assessing Protein Identity and Stability - The present invention relates to methods and other technologies that may be used to determine whether compositions (e.g., pharmaceutical compositions) comprising interleukin-10 molecules (e.g., pegylated interleukin-10) meet particular product-related specifications prior to being administered to a subject for the treatment and/or prevention of the diseases, disorders and conditions, and/or the symptoms thereof, described herein. | 2016-05-05 |
| 20160123992 | METHODS FOR PREDICTING RHEUMATOID ARTHRITIS TREATMENT RESPONSE - The invention relates to methods and means for predicting rheumatoid arthritis treatment response. | 2016-05-05 |
| 20160123993 | Collagen Type X Alpha-1 Assay - An antibody specifically reactive with an epitope of collagen type X alpha 1 comprised in the NC1 domain C-terminal amino acid sequence SFSGFLVAPM-COOH (SEQ ID NO: 1), and a method of immunoassay for detecting in a biological sample an epitope comprised in the NC1 domain C-terminal amino acid sequence SFSGFLVAPM-COOH (SEQ ID NO: 1) of collagen type X alpha 1, by contacting said biological sample with said antibody, and determining the amount of binding of said antibody. | 2016-05-05 |
| 20160123994 | AIDING ASSESSMENT OF PROGNOSIS IN INFLAMMATORY DISEASE - Some embodiments are directed to a method of collecting information useful in predicting clinical outcome in a subject, the method including providing a sample from said subject, and determining the level of octameric PTX3 in said sample, wherein determining the level of octameric PTX3 includes measuring the total amount of PTX3 present, and measuring the amount of octameric PTX3 present, and calculating the proportion of total PTX3 which is present as octamer, wherein if the proportion of octameric PTX3 is greater than 50%, the subject is identified as a likely non-survivor. Some embodiments are also directed to a method of collecting information useful in predicting clinical outcome in a subject, the method including providing a sample from said subject, and determining the level of octameric PTX3 in said sample, wherein an elevated level of octameric PTX3 compared to a reference level indicates a reduced likelihood of survival. | 2016-05-05 |
| 20160123995 | Biomarker of Rehospitalization After Heart Failure - The invention relates to a method for establishing if a heart failure patient is susceptible to be hospitalized and/or rehospitalized, wherein said method comprises measuring the concentration of IGFBP | 2016-05-05 |
| 20160123996 | METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE - The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect one or more markers selected from the group consisting of Prostatic acid phosphatase, Lactotransferrin, Soluble erythropoietin receptor, Von Willebrand factor, Soluble endothelial protein C receptor, and Beta-2-glycoprotein 1 as diagnostic and prognostic biomarkers in renal injuries. | 2016-05-05 |
| 20160123997 | MATERIALS AND METHODS RELATING TO ALZHEIMER'S DISEASE - The invention relates to methods and compositions relating Alzheimer's disease. There is provided a panel of optimal biomarkers which allow diagnosis of Alzheimer's disease and discrimination between Alzheimer's disease and its earlier precursor, mild cognitive impairment (MCI). | 2016-05-05 |
| 20160123998 | Devices, Systems, and Methods for Measuring Blood Loss - Devices, systems, and methods for measuring the blood loss of a subject during a medical procedure. Blood and other fluids are received within a container, and a blood measurement device determines the hemoglobin concentration of the fluid within the container. The blood measurement device can also calculate the estimated blood loss of the subject based upon the determined hemoglobin concentration and the volume of the fluid within the container and the patient's hemoglobin. | 2016-05-05 |
| 20160123999 | METHOD FOR MEASURING GLYCATED HEMOGLOBIN - The present invention provides a method for measuring glycated hemoglobin in a sample, which comprises directly oxidizing glycated hemoglobin in a sample, and then measuring a substance produced or consumed by the oxidation; and a method for measuring glycated hemoglobin in a sample, which comprises directly oxidizing glycated hemoglobin in a sample using an enzyme, and then measuring a substance produced or consumed by the oxidation. A method for measuring glycated hemoglobin of the present invention is useful for diagnosing lifestyle-related disease such as diabetes mellitus. | 2016-05-05 |
| 20160124000 | DETECTION OF PROTEIN TO PROTEIN INTERACTIONS - The present invention relates to methods and kits for detecting the interaction between a first membrane protein and a second protein in mammalian cells as well as to identify molecules that can disrupt protein to protein interactions. The invention relies on the functional reconstitution of an active human ubiquitin by two inactive fragments upon the interaction of two proteins attached through a linker to the inactive fragments. The reconstituted ubiquitin is then cleaved by human ubiquitin proteases resulting in the release of an artificial transcription factor, which in turn activates a reporter gene transcription. Activation of the reporter gene is indicative of the interaction between the two proteins. | 2016-05-05 |
