18th week of 2011 patent applcation highlights part 62 |
Patent application number | Title | Published |
20110105788 | Polymorphic Form of an Aminoindan Mesylate Derivative - The invention relates to a polymorphic form of rasagiline mesylate, and to processes for preparing the same. | 2011-05-05 |
20110105789 | METHOD FOR PRODUCING CATALYST FOR PREPARATION OF METHACRYLIC ACID AND METHOD FOR PREPARING METHACRYLIC ACID - A method for producing a catalyst for the preparation of methacrylic acid comprising a heteropolyacid compound containing phosphorus, molybdenum and an element X selected from the group consisting of potassium, rubidium, cesium and thallium and having an atomic ratio of the element X to molybdenum of 0.5:12 to 2:12, which method comprises the steps of mixing aqueous slurry A containing starting compounds of the heteropolyacid compound in which an atomic ratio of the element X to molybdenum is from 2:12 to 4:12, and aqueous slurry B containing starting compounds of the heteropolyacid compound in which an atomic ratio of the element X to molybdenum is from 0:12 to 0.5:12 to form a slurry mixture; heat-treating the slurry mixture at a temperature of 100° C. or higher; drying the slurry mixture; and calcining the dried mixture. | 2011-05-05 |
20110105790 | METHOD FOR THE PRODUCTION OF A NANOCRYSTALLINE MOLYBDENUM MIXED OXIDE - A method for the production of a nanocrystalline molybdenum mixed oxide, the use of the molybdenum mixed oxide as catalyst for chemical conversions, in particular for a conversion of acrolein to acrylic acid as well as a catalyst that contains the molybdenum mixed oxide. | 2011-05-05 |
20110105791 | PROCESS FOR PREPARING ACRYLIC ACID PURIFIED BY CRYSTALLIZATION FROM HYDROXYPROPIONIC ACID AND APPARATUS THEREFORE - The invention relates to a process for the preparation of acrylic acid and a process for the preparation of polyacrylic acid comprising the process steps: (a1) preparation of 3-hydroxypropionic acid from a biological material to give a fluid, in particular aqueous, phase containing 3-hydroxypropionic acid; (a2) dehydration of the 3-hydroxypropionic acid to give a fluid, in particular aqueous, solution containing acrylic acid; (a3) purification of the solution containing acrylic acid by a suspension crystallization or a layer crystallization to give a purified phase; and corresponding devices for carrying out these processes, and acrylic acid and polyacrylates. The invention is distinguished in that acrylic acid and polyacrylates can thereby be prepared efficiently, inexpensively, and sustainably with simple means and with a high purity on the basis of regenerable raw materials. | 2011-05-05 |
20110105792 | Process for producing allyl acetate - A process for producing allyl acetate is disclosed. The process comprises reacting propylene, acetic acid, and oxygen in the presence of a supported palladium catalyst in an adiabatic reactor. | 2011-05-05 |
20110105793 | METHOD FOR SEPARATING AMIDE FROM AMINO ACID IONIC LIQUID - The present invention provides a method for separating an amide from an amino acid ionic liquid. The method includes the step of providing a polar solvent and an extracting agent to the amino acid ionic liquid, so as to separate the amide from the amino acid ionic liquid. In the method of the present invention, there is no need to add ammonium for neutralization, such that no byproduct, ammonium sulfate, is formed. In addition, after the amide is separated from the amino acid ionic liquid, the amino acid ionic liquid can be recycled. | 2011-05-05 |
20110105794 | Process for the Isomerization of Semicarbazone Compounds - The present invention relates to a process for the isomerization of the Z-isomer I-Z of a semicarbazone compound of the general formula (I) into its E-isomer I-E | 2011-05-05 |
20110105795 | PROCESS FOR PREPARATION OF TERIFLUNOMIDE - The present invention provides a process for preparing Teriflunomide of formula (I). | 2011-05-05 |
20110105796 | Tetraarylborate Process for the Preparation of Substituted Biphenyls - The present invention relates to a process for the preparation of substituted biphenyls by reacting aryl halides with tetraarylborates in the presence of palladium catalysts. | 2011-05-05 |
20110105797 | Creatinol sulfate and synthesis method thereof - A chemical compound of creatinol sulfate is formed by chemically reacting N-methyl-amino-ethanol, cyanamide, with sulfuric acid to produce the creatinol sulfate with relatively higher yield rate and purity, wherein the mol ratio of N-methyl-amino-ethanol, sulfuric acid, and cyanamide is approximately 2:1:2. | 2011-05-05 |
20110105798 | SYNTHESIS OF CHIRAL AMINES - The instant invention involves the enantioselective hydrogenation of isomeric N—H imines (N-unsubstituted) using a transition metal based catalyst modified with a chiral phosphine derivative to produce enantiomerically enriched chiral amines. | 2011-05-05 |
20110105799 | PROCESS FOR THE SYNTHESIS OF CINACALCET HYDROCHLORIDE - There is described a process for the preparation of cinacalcet hydrochloride (I) which includes the steps of: a) reacting (R)-(+)-1-(1-naphthyl)ethylamine (II) with 3-[3-(trifluoromethyl)phenyl]propenaldehyde (III) to afford the non isolated intermediate (R)—N-[3-[3-(trifluoromethyl)phenyl]-2-propenylimino-N-[1-(1-naphthyl)ethylamine (IV); b) reducing the non isolated intermediate (R)—N-[3-[3-(trifluoromethyl)phenyl]-2-propenylimino-N-[-1-(1-naphthyl)ethylamine (IV) with a sequential addition of:—a solution of sodium borohydride, methanol and a base,—oxalic acid and − a base to obtain (R)—N-[3[3-(tifluoromethyl)phenyl]-2-propenyl]-1-(1-naphthyl)ethylamine (V) by passing through the precipitation of the oxalate salt of compound (V) after the addition of oxalic acid; c) hydrogenating (R)—N-[3-[3-(trifluoromethyl)phenyl]-2-propenyl]-1-(1-naphthyl)ethylamine (V) thus obtaining (R)—N-(3-(3-(trifluoromethyl)phenyl]propyl]-1-(1-naphthyl)ethylamine cinacalcet base (VI), which is retaken in ethyl acetate; and d) treating the solution of cinacalcet base (VI) in ethyl acetate with hydrochloric acid to afford cinacalcet hydrochloride (I). | 2011-05-05 |
20110105800 | FACILE SYNTHESIS OF 3-AMINOPICRIC ACID - Embodiments of methods for preparing 3-aminopicric acid from picric acid is described. In one embodiment, the method comprises combining lithium hydroxide, picric acid, and a first solvent to form a first solution, combining lithium hydroxide, hydroxylamine hydrochloride, and a second solvent to form a second solution, combining the first solution with the second solution to form a mixture, and cooling the mixture. | 2011-05-05 |
20110105801 | FORMALDEHYDE SYNTHESIS - A process is disclosed for the synthesis of formaldehyde from methane starting with the oxychlorination of methane to produce methylene chloride. Hydrolysis of methylene chloride yields the product formaldehyde. Gaseous formaldehyde is condensed for shipment. Byproduct chloroform and carbon tetrachloride are recovered and hydrogenated to provide additional methylene chloride. | 2011-05-05 |
20110105802 | Continuous Loop Flow Process For Polyether Polyol Production - The present disclosure relates, according to some embodiments, to compositions, apparatus, methods, and systems that may be used to produce polyols, for example, polyether polyols with a narrow range of molecular weights, with little if any unsaturated byproducts, in a sustained and/or continuous reaction, with efficient heat transfer, and/or at high production rates. For example, in some embodiments, teachings of the disclosure may be used to produce polyether polyols in a continuous loop flow process. A continuous loop flow process may be practiced such that heat is effectively transferred and/or product properties (e.g., range of molecular weights) are controllable. For example, a continuous loop flow process may use one or more continuous flow loops comprising a heat exchanger, a means to move material around each loop, inlets for catalyst, monomer, initiator or starter, and an outlet for polyol product. | 2011-05-05 |
20110105803 | METHOD OF SYNTHESIZING SEVOFLURANE - The present invention provides a method of synthesizing sevoflurane, which comprises the following steps: taking hexafluoro isopropanol as the starting material and reacting it with trioxymethylene (or paraformaldehyde) in the presence of acid to generate dihexafluoro isopropanol formal derivatives, adding anhydrous aluminum trihalide to generate halomethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether, then reacting the halomethyl compound with metal fluoride to form the sevoflurane. The method is of low cost, and the reaction condition is easy to implement, and produces sevoflurane in large scale. | 2011-05-05 |
20110105804 | Process for producing nitroalcohols - Nitroaldol (“Henry”) reactions between nitroalkanes and aldehydes in the presence of a catalyst and a two-phase reaction medium produce nitroalcohols at increased reaction rates compared to single-phase organic solvent systems, and do not require use of surfactants as is typical of single-phase aqueous solvent systems and solventless systems. The reaction medium comprises an organic solvent phase and an aqueous solvent phase. The aqueous solvent may be 100% water. | 2011-05-05 |
20110105805 | Process for Producing Phenol - In a process for producing phenol, cyclohexylbenzene is oxidized to produce cyclohexylbenzene hydroperoxide and then the resultant cyclohexylbenzene hydroperoxide is cleaved to produce an effluent stream comprising phenol and cyclohexanone. At least a portion of the effluent stream is then fed to at least one dehydrogenation reaction zone, where the effluent stream portion is contacted with a dehydrogenation catalyst under conditions effective to convert at least part of the cyclohexanone in the effluent portion into phenol and hydrogen. | 2011-05-05 |
20110105806 | METHOD FOR ELIMINATING COLOR FORMING IMPURITIES FROM NITRO COMPOUNDS - A method for stabilizing nitro compounds against discoloration. The method comprises reacting nitro compounds containing color-forming impurities with nitric acid, neutralizing and washing the product, and distilling therefrom purified nitro compounds. | 2011-05-05 |
20110105807 | Integrated Process for Fluoro-Olefin Production - Disclosed is a process for the manufacture of HFO-1234yf from TCP in three integrated steps that include hydrofluorination of TCP (tetrachloropropene) to HCFC-1233xf in the vapor phase followed by hydrofluorination of HCFC-1233xf to HCFC-244bb in the liquid phase which is then followed by dehydrochlorination in liquid or vapor phase to produce HFO-1234yf. The vapor phase hydrofluorination is carried out at a higher pressure than the liquid phase hydrofluorination, thereby eliminating the need for compression and/or intermediate recovery. Also, any HCl generated from this reaction is fed to the liquid phase hydrofluorination section to promote agitation and mixing. This results in a more economical process from an initial capital and operating cost versus conducting the 3-steps sequentially. | 2011-05-05 |
20110105808 | Process for the Preparation of 1,1,3,3,3-Pentafluoropropene and 1,2,3,3,3-Pentafluoropropene - A process for the manufacture of CF | 2011-05-05 |
20110105809 | PROCESS FOR THE PURIFICATION OF 2,3,3,3-TETRAFLUORO-1-PROPENE (HFO-1234YF) - The subject of the invention is a process for the purification of 2,3,3,3-tetrafluoro-1-propene (HFO-1234yf). More particularly, it relates to a purification process in which 2,3,3,3-tetrafluoro-1-propene, comprising impurities based on halogen compounds, is brought into contact with an adsorbent, preferably molecular sieves and advantageously molecular sieves having a pore opening with an average diameter between 5 and 11 Å, preferably between 5 and 9 Å. | 2011-05-05 |
20110105810 | CATALYZED OLEFIN INSERTION - A process for the insertion of a fluorinated olefin into a fluorinated iodide in the presence of a nickel catalyst at a temperature of a maximum of 150° C. with an initial rate of 0.04 mole/hour without loss of selectivity is disclosed. | 2011-05-05 |
20110105811 | PRODUCTION OF DISTILLATE BLENDING COMPONENTS - A process to produce an alkylate distillate blending component in one embodiment comprising: providing at least one olefinic C5+ product which was produced by conversion of synthesis gas in a Fischer Tropsch process; and alkylating the olefinic C5+ product in the presence of an acidic ionic liquid alkylation catalyst with hydrocarbons selected from the group consisting of isoparaffins, cycloparaffins, and their mixtures to form an alkylate distillate blending component is described. | 2011-05-05 |
20110105812 | CONTROLLING COLD FLOW PROPERTIES OF TRANSPORTATION FUELS FROM RENEWABLE FEEDSTOCKS - A process for improving cold flow properties of diesel range hydrocarbons produced from renewable feedstocks such as plant oils and animal oils. A renewable feedstock is treated by hydrogenating and deoxygenating to provide an effluent comprising paraffins followed by isomerizing and selectively hydrocracking at least a portion of the paraffins to generate a diesel range hydrocarbon product. A portion of the diesel range hydrocarbon product is selectively separated and recycled to the isomerization and selective hydrocracking zone. | 2011-05-05 |
20110105813 | PROCESS FOR CONVERSION OF BIOMASS TO FUEL - The present invention is directed to processes for the direct conversion of lipidic biomass fuelstock to combustible fuels. In particular, the invention provides a process for the direct conversion of animal fats to transportations fuels suitable as replacement for petroleum-derived transportation fuels. In one embodiment, the method comprises the steps of hydrolyzing a lipidic biomass to form free fatty acids, catalytically deoxygenating the free fatty acids to form n-alkanes, and reforming at least a portion of the n-alkanes into a mixture of compounds in the correct chain length, conformations, and ratio to be useful transportation fuels. Particularly, the product prepared according to the invention comprises mixtures of hydrocarbon compounds selected from the group consisting of n-alkanes, isoalkanes, aromatics, cycloalkanes, and combinations thereof. | 2011-05-05 |
20110105814 | PROCESS FOR PRODUCING A HYDROCARBON COMPONENT - The invention relates to a process for producing a new type of high-quality hydrocarbon base oil of biological origin. The process of the invention comprises ketonisation, hydrodeoxygenation, and isomerization steps. Fatty acids and/or fatty acid esters based on a biological raw material are preferably used as the feedstock. | 2011-05-05 |
20110105815 | Process to Make Olefins from Ethanol - The present invention relates to a process for the conversion of ethanol to make essentially ethylene and propylene, comprising:
| 2011-05-05 |
20110105816 | Production of Aromatics from Methane - In a process for converting methane to aromatic hydrocarbons, a feed containing methane is contacted with a dehydrocyclization catalyst in a reaction zone under conditions effective to convert the methane to aromatic hydrocarbons. The reaction zone is contained within a reactor and the reactor or an internal component of the reactor has at least one surface that is chemically exposed to the feed and is formed from a refractory material that exhibits a carbon uptake (mass of carbon absorbed per unit of exposed metal surface area) of less than 25 g/m | 2011-05-05 |
20110105817 | PROCESS FOR THE CONVERSION OF FATTY ACIDS AND DERIVATIVES THEREOF - A process for the production of a hydrocarbon product comprises contacting a feedstock with a catalyst composition comprising an active metal selected from platinum, palladium, nickel, cobalt, copper, ruthenium, rhodium and rhenium and an active porous material which is active for the isomerisation of unsaturated hydrocarbons, wherein the feedstock comprises a fatty acid a fatty acid ester, a monoglyceride, a diglyceride or a triglyceride. | 2011-05-05 |
20110105818 | Dehydrogenation Catalyst with a Water Gas Shift Co-Catalyst - A catalyst comprising a dehydrogenation catalyst and a water gas shift co-catalyst can be used for the dehydrogenation of alkylaromatic hydrocarbons to alkenylaromatic hydrocarbons. For instance, the catalyst can be used for the dehydrogenation of ethylbenzene to styrene. The catalyst can include an iron compound, a potassium compound, and a cerium compound. | 2011-05-05 |
20110105819 | ZEOLITE CATALYST ZEOLITE SECONDARY STRUCTURE - A zeolite secondary structure essentially free from binders and formed from zeolite powder (primary particles), wherein the tensile strength of the secondary structure is at least about 0.4 MPa. The use of the zeolite secondary structure materials as catalyst in hydrocarbon conversion processes. | 2011-05-05 |
20110105820 | STABILIZED IONIC LIQUID CATALYZED PROCESSES - Methods and compositions for stabilizing the activity of catalytic compositions during catalytic processes, such as alkylation. A catalytic composition comprising a partially deactivated ionic liquid catalyst may be regenerated by reaction with a metal to form reactivated catalyst and an inorganic catalyst precursor; and the catalytic composition may be amended in-process by addition of an organic catalyst precursor for reaction with the inorganic catalyst precursor to form fresh ionic liquid catalyst. The organic catalyst precursor may be protected from water, e.g., during handling, by hydrophobic material(s). | 2011-05-05 |
20110105821 | Quick Regulation of the Range of High-Energy ION Beams for Precision Irradiation of Moving Target Volumes - The invention concerns a device and a process for adjusting the range of an ion beam, in particular for irradiation in tumor therapy. For this purpose, first the reference position of a target volume to be irradiated is determined. Subsequently, the range of an ion beam is configured such that said beam is adjusted to the reference position of the target volume, in such a manner that the Bragg peak, i.e. the maximal energy loss and thereby the maximal damage occurs in the region of the target volume which is to be destroyed. In the case that it has been determined that the reference position has been altered by a movement of the target volume, the ion beam is then deflected from the beam axis such that the ion beam is directed to various regions of a range modulator, in order that the ion beam experience a correspondingly adjusted energy loss in passing through the range modulator. This energy loss is adjusted to correspond to the change in position of the target volume in such a manner that the change in position is compensated for by the adjustment of the range of the ion beam, and the Bragg peak is returned to the region within the target volume. | 2011-05-05 |
20110105822 | BALLOON CATHETER AND X-RAY APPLICATOR COMPRISING A BALLOON CATHETER - The invention relates to a balloon catheter for an X-ray applicator and an X-ray applicator—for use with the corresponding balloon catheter. Said balloon catheter can be filled with a medium and comprises a balloon—that expands with respect to the volume and a catheter shaft for inserting the X-ray applicator. Said balloon or the catheter shaft comprises a rigid inner end piece in the extension of the catheter shaft. | 2011-05-05 |
20110105823 | Medical Template Device and Method for Use in Positioning Therapeutic Probes at a Target Tissue - Medical template device and method for use in positioning therapeutic probes at a target tissue are provided. The template device includes a frame and a pierceable probe guide secured by the frame. The probe guide has a probe guide pattern such as a grid pattern, wherein the pierceable probe guide is capable of being pierced at any location along its surface by a therapeutic probe. In one embodiment, the pierceable probe guide is a film having a solid surface without any pre-formed apertures. This allows a physician to more accurately position the probes with narrower spacing. | 2011-05-05 |
20110105824 | PARASYMPATHETICALLY INDUCED VASODILATATION METHOD AND APPARATUS - A method and treatment device for inducing vasodilatation in a target vasculature of a patient. The method can include introducing an energy-supplying treatment instrument to a sinus cavity which provides access to a parasympathetic ganglion neurologically associated with the target vasculature. The method can also include applying non-electrical stimulant energy from the treatment instrument into the sinus cavity in a manner to stimulate the parasympathetic ganglion. The treatment device can be used to practice the method. | 2011-05-05 |
20110105825 | Nanoparticle-sized magnetic absorption enhancers having three-dimensional geometries adapted for improved diagnostics and hyperthermic treatment - Nanoparticle-sized magnetic absorption enhancers (MAEs) that exhibit a controlled response to a magnetic field, including a controlled mechanical response and inductive thermal response. The MAEs have a magnetic material that exhibits the inductive thermal response to the magnetic field and is embedded in a coating, such that the MAE conforms to a particular shape, e.g., a hemisphere, a dome or a shell, that is chosen to produce the desired controlled mechanical response of the entire MAE to the magnetic field. A targeting moiety for specifically binding the MAE to a pathogen target is also provided. The MAEs are preferably bound by a flexible linker to promote the desired mechanical response, which includes interactions between MAEs that are not bound to their pathogen target for the purpose of forming spheres, spherical shells, or generally spherical dimers. Such forms contain the thermal energy produced by the thermal inductive response of the magnetic material and thus reduce collateral healthy tissue damage during hyperthermic treatment. The inventing extends to appropriate apparatus and methods for diagnostics and hyperthermic treatments employing the MAEs. | 2011-05-05 |
20110105826 | TRANSCRANIAL MAGNETIC STIMULATION BY ENHANCED MAGNETIC FIELD PERTURBATIONS - Described herein are devices, systems and methods to enhance the magnetic perturbation of a neuronal (e.g., brain) target during Transcranial Magnetic Stimulation (TMS), thereby enhancing the induced current in the target. In general, these devices, systems and methods enhance the magnetic perturbation (dB/dt) of the target by mechanically moving a TMS electromagnet (e.g. coil) at a frequency of greater than 1 kHz. | 2011-05-05 |
20110105827 | Method and device for the treatment of overweight - A device and a method of applying the device for the treatment of obesity or overweight in mammals, especially humans refers to a suitable substrate to be worn at the body of the patient and includes a thyroid stimulating pulsating magnetic field, whereby the magnetic field can be controlled and programmed as to the duration, frequency and pulsation of the magnetic field. | 2011-05-05 |
20110105828 | Methods of treating a body part - The invention generally relates to devices and methods for treating a body part using magnets. In certain embodiments, the invention provides a device for treating a body part including a carrier and a plurality of magnets, in which the magnets are configured to correspond with a plurality of acupuncture meridian points upon application of the device to the body part. | 2011-05-05 |
20110105829 | Implantable Signal Delivery Systems - An implantable hearing prosthesis is described for a recipient patient. An implantable receiving coil receives an externally generated communication data signal. An implantable signal processor is in communication with the receiving coil for converting the communication data signal into a transducer stimulation signal. An implantable enclosed acoustic transducer is in communication with the signal processor for converting the transducer stimulation signal into an acoustic signal for generating acoustic vibrational stimulation of one or more hearing structures in the middle ear of the patient. The transducer can be enclosed in an implantable signal delivery baffle. A probe microphone system includes a baffle to seal middle ear structures to reduce ambient noise pickup. | 2011-05-05 |
20110105831 | Sling Delivery System and Method of Use - An apparatus and method of use are disclosed to treat urological disorders. The biocompatible device includes a handle, needle, dilator and sling assembly configured to be minimally invasive and provide sufficient support to the target site. In addition, the configuration of the sling assembly also allows the sling to be adjusted during and/or after implantation. The device and treatment procedure are highly effective and produce little to no side effects or complications. Further, operative risks, pain, infections and post operative stays are reduced, thereby improving patient quality of life. | 2011-05-05 |
20110105832 | Surgical Articles for Placing an Implant about a Tubular Tissue Structure and Methods - A minimally invasive surgical instrument for placing an implantable article about a tubular tissue structure is disclosed. The surgical instrument is particularly useful for treating urological disorders such as incontinence. Surgical methods using the novel instrument are also described. | 2011-05-05 |
20110105833 | TRANSOBTURATOR METHODS FOR INSTALLING SLING TO TREAT INCONTINENCE, AND RELATED DEVICES - Described are methods of treating urinary incontinence using a urinary sling and a tissue path that passes through the obturator foramen, along with related surgical implants, devices, systems, and kits. | 2011-05-05 |
20110105834 | IMAGING AND EVALUATING EMBRYOS, OOCYTES, AND STEM CELLS - Methods, compositions and kits for determining the developmental potential of one or more embryos or pluripotent cells and/or the presence of chromosomal abnormalities in one or more embryos or pluripotent cells are provided. These methods, compositions and kits find use in identifying embryos and oocytes in vitro that are most useful in treating infertility in humans. | 2011-05-05 |
20110105836 | System and Method for Treating Prolapse and Incontinence - A system and method of treating vaginal prolapse and incontinence comprises a kit. The kit includes a mesh graft configured for attachment to the anterior and posterior vaginal walls to thereby treat the vaginal prolapse. A graft delivery device is also provided for introducing and placing the mesh graft to a location deep within the peritoneal cavity and for attaching the graft thereto. A leg assembly is provided and coupled to an end of the mesh graft and cooperates with the graft delivery device to anchor and affix the mesh graft to the desired anatomical structures. The method according to the present invention contemplates a laparoscopic graft placement utilizing the components of the kit. | 2011-05-05 |
20110105838 | SUCTION DEVICE FOR ENDOSCOPIC INSTRUMENTS AND METHOD - The present invention is related to a suction device especially designed for endoscopic instruments, including at least two cylindrical suction ports located at both sides of the distal end of the endoscopic instrument. Each suction port has inside and next to the distal end thereof at least one sharp traversing blade. Each suction port is connected to a suction line in turn connected to a suction pump. The external end of said suction line is connected to a disposal recipient into which the debris, blood, coagula, etc. removed from the surgical site will be disposed. | 2011-05-05 |
20110105839 | ENDOSCOPIC APPARATUS WITH INTEGRATED MULTIPLE BIOPSY DEVICE - An imaging endoscope comprising a shaft having a proximal end adapted to be secured to a handle, and a distal end having a biopsy forceps disposed therein. The biopsy forceps includes one or more end-effector elements that are actuated with a control cable that may be connected to the handle. The endoscope shaft includes a biopsy sample lumen that is configured to receive a biopsy sample obtained from the forceps assembly. A sample collection apparatus is attached to the handle to capture multiple biopsy samples. In some embodiments, the endoscope is a single-use endoscope. | 2011-05-05 |
20110105840 | ASSEMBLIES FOR USE WITH AN ENDOSCOPE - An expander for mounting a resilient outer tubular article over an elongate article including a chassis element having associated therewith at least one outwardly movable element which is selectably engageable with at least a portion of the resilient outer tubular article, a driver which is movable with respect to the chassis element and is operative to selectably engage the at least one outwardly movable element, when the outwardly movable element is in engagement with the at least a portion of the resilient outer tubular article, for producing corresponding outward motion and outward expansion thereof and an engagement element, associated with the driver, for insertion into the at least a portion of the resilient outer tubular article upon expansion thereof by operation of the driver, the engagement element being configured to accommodate at least a portion of the elongate article. | 2011-05-05 |
20110105841 | MEDICAL INSTRUMENT SYSTEM AND METHOD FOR MANIPULATING TARGET TISSUE - A method is provided for manipulating target tissue of a patient during a medical procedure. The method includes introducing a medical instrument system to a general site of target tissue. At least one characteristic of the target tissue is identified using an imaging device located in a working channel of the medical instrument system. The imaging device is removed from the working channel of the medical instrument system, and a medical instrument is inserted through the working channel of the medical instrument system. The target tissue is then manipulated using the medical instrument. A medical instrument system is also provided for manipulating target tissue of a patient during a medical procedure. | 2011-05-05 |
20110105842 | SUCTION DEVICE FOR LAPAROSCOPIC INSTRUMENTS AND METHOD - The present invention is related to a suction device especially designed for laparoscopic and/or arthroscopic instruments, including at least two cylindrical suction ports located at both sides of the distal end of the laparoscopic and/or arthroscopic instrument. Each suction port has inside and next to the distal end thereof at least one sharp traversing blade. Each suction port is connected to a suction line in turn connected to a suction pump. The external end of said suction line is connected to a disposal recipient into which the debris, blood, coagula etc removed from the surgical site will be disposed. | 2011-05-05 |
20110105843 | Surgical Instrument With Tendon Preload-and-Locking Device - A surgical instrument includes a handle, an elongated shaft and an end effector extending distally from the shaft. A tensile member is preloaded with a tensile force and extends at least partially through the shaft. A preload mechanism for adjusting the tensile force includes first and second guides in contact with the tensile member to restrain the tensile member at respective first and second lateral distances from a longitudinal axis. A third guide is disposed longitudinally between the first and second guides and is in contact with the tensile member to restrain the tensile member at a third lateral distance from the longitudinal axis. The third guide is movable to vary the third lateral distance and a corresponding length of the tensile member disposed longitudinally between the first and second guides to thereby vary the tensile force. | 2011-05-05 |
20110105844 | MANUALLY CONTROLLED ENDOSCOPE - A control handle for use with a steerable endoscopic device. The endoscopic device having a pair of control wires to effect steering. The control handle includes a steering mechanism that includes an actuator, such as a control knob, drivingly connected to a drive member, such as a sprocket or drive gear. To transmit force from the drive member to the control wires, a length of transmission structure, such as bead chain, is connected to the proximal ends of the control wires and is engaged with the drive member. In one embodiment, a single-use endoscope may be provided, which includes a control handle, a steerable endoscopic device, and a umbilical cord or communications conduit for functionally connecting the control handle to a control cabinet of an endoscopic imaging system. | 2011-05-05 |
20110105845 | ENDOSCOPIC DEVICE WITH FLUID CLEANING - A method for enhancing performance of an endoscope ( | 2011-05-05 |
20110105846 | ACTUATOR SYSTEM AND ENDOSCOPE APPARATUS - An actuator system including a drive section that performs driving by injection/suction of a liquid, a tube, a syringe pump that injects/suctions the liquid into/from the drive section via the tube, a pressure sensor that measures an inner pressure, a storage section that preliminarily stores a volume change ΔV of the tube caused by the inner pressure, and a control section that controls the syringe pump based on the volume change ΔV, inner pressure P, and volume V | 2011-05-05 |
20110105847 | ENDOSCOPE INCLUDING A VARIABLE STATE OPTICAL MEMBER - In one embodiment, an apparatus may include an elongate member having a proximal end portion and a distal end portion. A variable state optical member may be coupled within the distal end portion of the elongate member. The variable state optical member may include a first configuration and a second configuration different from the first configuration. An imager may be disposed within the distal end portion of the elongate member. The imager may be configured to produce an imaging signal associated with a tissue distal to the elongate member when the variable state optical member is in the first configuration. The imager may be also configured to produce an imaging signal associated with a tissue lateral to the elongate member when the variable state optical member is in the second configuration. | 2011-05-05 |
20110105848 | LAPAROSCOPIC TISSUE RETRACTOR - The present invention is primarily directed to a surgical retractor suitable for laparoscopic insertion, comprising an elongate shaft having two or more arms at its distal end, and a mechanism for controlling the mutual separation of said arms located at its proximal end, wherein a membrane is attached to said two or more arms, such that upon mutual separation of said arms, said membrane forms a non-planar surface suitable for use as a barrier for retracting or holding tissues or organs. | 2011-05-05 |
20110105849 | Devices and Methods for Minimally Invasive Access to Sinuses and Treatment of Sinusitis - The present invention provides minimally invasive devices and methods for accessing the sinuses and their surrounding structures for surgery and other treatments. The anterior ethmoid and maxillary sinuses are accessed and treated under minimal anesthesia with little or no postoperative limitation of activity or adverse symptoms. Direct visual verification of the sinuses and their natural ostia is utilized. Other paranasal sinuses may be treated by this method as well. The sinuses, in particular the maxillary and anterior ethmoid, are accessed via a direct anterior to posterior axis and the natural ostia of those sinuses is directly visualized for placement of a guide-free dilator, in the desired location within the natural ostia. That access to the maxillary ostium is accomplished by the anterior transuncinate “keyhole” approach in which a hole is punched in the uncinate process with the described devices according to the described methods. The properly placed dilator is expanded to allow drainage of the inflamed sinus and then withdrawn. An analogous ethmoid bulla “keyhole” approach and subsequent dilation are used for the anterior ethmoid sinus ostia. Pharmaceutical agents may be placed at desired locations in the sinuses using the same access technique. | 2011-05-05 |
20110105850 | VAGINAL ENTRY SURGICAL DEVICES, KIT, SYSTEM, AND METHOD - A surgical method, system, kit, and various devices are provided for use in, among other things, vaginal entry during a natural orifice translumenal endoscopic surgical procedure. A system and/or method provide for the rapid creation of a conduit and/or multiple ports in a natural orifice, such as a patient's vagina, while accommodating anatomical variation to reduce the need to excise additional tissue from the patient. | 2011-05-05 |
20110105851 | Headlight apparatus and method - A portable headlight assembly for illuminating a surgical site when look at by a practitioner and moves with the surgeon operates only when the light energy is directed toward the site. A headlight source has a HID lamp to illuminate via a light cable coupled to receive and transmit the illumination in the range of natural daylight between 5000 and 6700 degrees Kelvin. A power supply couples to the HID lamp when the light cable is located to receive focused light from it. A control monitors the operation of the headlight source and the portable power supply and is responsive to temperature of the portable power supply and radiation supplying illumination. The light cable extends between the HID lamp to guide illumination from the HID lamp and its reflector to a lens In a head strap worn by the practitioner for delivering the illumination towards the surgical site to enhance the color spectra of the visual field during surgery providing observation with depth of field and natural coloration. A method of using the portable headlight safely to illuminate a surgical site has steps of positioning it for movement by or with the surgeon. Supplying illumination at the surgical site with a headlight source having a HID lamp able via a light cable when coupled to make, receive and transmit illumination in the range of natural daylight between 5000 and 6700 degrees Kelvin and energizing with a portable power supply if coupled to the HID lamp when a light cable is located to received focused light from the HID lamp for operating the HID lamp when the light energy is directed toward the surgical site are steps. The step of monitoring the operation with a control responsive to temperature of the HID lamp and the portable power supply wherein the control responds to the level of heat in the portable power supply, and the headlight source. Extending the light cable between the HID lamp and a mount positioned on the head of a surgeon is a step for aiming the illumination toward the surgical site for enhancing the color spectra of the visual field during surgery providing surgeon observation including depth of field and natural colorations during surgery. | 2011-05-05 |
20110105852 | USING DATA IMPUTATION TO DETERMINE AND RANK OF RISKS OF HEALTH OUTCOMES - Techniques for generating prediction of risks of medical outcomes and benefit scores for medical interventions, with imputation of missing patient data values, are disclosed. Apparatus or computer program products may be configured to receive a patient record for the patient from a database of a data storage unit, wherein one or more demographic data values or biometric data values in the patient record are missing or have null values; create and store a plurality of clone patient records in the database; impute a plurality of different substitute demographic data values or biometric data values and substitute a different one of the plurality of substitute values into each one of the clone patient records; determine, create and store a first metric, based at least in part on the clone patient records, wherein the first metric comprises a current health related metric for the patient; determine, create and store one or more medical intervention metrics, each based at least in part on an associated medical intervention and the clone patient records, representing a predicted health related metric for the patient when the associated medical intervention is performed; transform the database by updating the patient record to include the first metric and the one or more medical intervention metrics. | 2011-05-05 |
20110105853 | SYSTEMS AND METHODS FOR HEALTHCARE DELIVERY, OBSERVATION, AND COMMUNICATION BETWEEN A DE-CENTRALIZED HEALTHCARE SYSTEM AND A PATIENT LIVING AT HOME - The disclosure describes de-centralized healthcare systems and methods of using the same to provide healthcare to a subject living at home. A de-centralized healthcare system of the invention provides at or above hospital-level care through the implementation of care pathway protocols for effective treatment of designated health conditions. A subject is monitored by a central station, which is staffed by healthcare practitioners and providers. A dispatch system allows healthcare providers to visit the subject for appointments and deliveries. The de-centralized healthcare system provides for the subject's laboratory, nutrition, and hygiene needs. | 2011-05-05 |
20110105854 | MEDICAL MONITORING SYSTEM - Medical patient monitoring devices that have the capability of detecting the physical proximity of a clinician are disclosed. The medical patient monitoring devices may be configured to perform a first selected action when the presence of a clinician is detected in a first detection area, and to perform a second selected action when the presence of the clinician is detected in a second detection area. The medical patient monitoring devices may be configured to determine whether a clinician is present in a detection area based on the strength of a signal from a clinician token, and based on a signal strength adjustment value associated with the clinician token. When the presence of a clinician is detected in a detection area, the medical patient monitoring devices may be configured to perform a predetermined action that is determined from a remote database communicatively coupled thereto. | 2011-05-05 |
20110105855 | EARLY DETECTION OF COGNITION IMPAIRMENT IN ELDERLY POPULATION - We have discovered novel methods and systems for detecting cognitive impairment in a subject by analyzing the level of xantophylls in macula lutea or red blood cell sample from the subject. We have discovered that decrease of xanthopyll level in the subject is indicative of cognitive impairment. | 2011-05-05 |
20110105856 | Diagnostic testing - One or more living entities are evaluated for health conditions by taking samples, especially samples of volatile compounds, derived from, e.g., the breath, urine, feces, saliva, skin exudates, etc., from the living entities, optionally with concentration of the samples; analyzing the samples using a multivariate analytical test; comparing the patterns present in the results of said test or tests, either; a. on an individual entity at a previous time to the patterns present in the results of said test or tests on the individual entity at the present time, or b/ comparing the patterns present in the results of the test on the said living entities to the patterns present in the results of tests on populations of similar entities having a normal health condition and/or to the patterns in the results of tests on populations of similar entities having a given disease or abnormal health condition, the results from the entities having normal health and each of the populations of entities having a given disease or abnormal condition being treated as reference sets for their respective specific disease or abnormal condition as compared to the reference set for entities having normal health. | 2011-05-05 |
20110105857 | IMPRESSION DEGREE EXTRACTION APPARATUS AND IMPRESSION DEGREE EXTRACTION METHOD - An impression degree extraction apparatus which precisely extracts an impression degree without imposing a strain on a user in particular. A content editing apparatus ( | 2011-05-05 |
20110105858 | METHOD AND APPARATUS TO MONITOR CHANGE IN INSPIRATORY EFFORT USING INTRATHORACIC BLOOD PRESSURE WAVEFORM MORPHOLOGY - An implantable medical device and associated method detect obstructed inspiration by monitoring an blood pressure signal. A respiration signal is monitored and a phase of respiratory inspiration is detected from the respiration signal. A trend in the pressure signal is measured during the inspiration phase. Obstructed inspiration for the inspiration phase is detected in response to the measured the trend. | 2011-05-05 |
20110105859 | Adaptive Performance Trainer - Techniques for accelerating training through optimization of the psychophysiological state of the trainee are provided. These techniques include an adaptive performance training system configured to acquire, analyzed, display, and translate data that reflects the psychophysiological state of the user, including the electrical activity of the brain (EEG), the heart (EKG), the musculature (EMG), respiration and other parameters that characterize the state of the user in real-time. The system includes a plurality of feedback mechanisms for providing visual, auditory, and/or tactile feedback based on the current psychophysiological state of the user and for facilitating moving the user toward a goal psychophysiological state for performing a particular task and for optimizing performance of that task. | 2011-05-05 |
20110105860 | DETECTING WORSENING HEART FAILURE - A method comprises monitoring a heart rate, a respiration rate and an activity level of a patient, comparing the monitored heart rate, respiration rate and activity level to a predetermined threshold zone which is a function of heart rate, respiration rate and activity level, determining the patient is experiencing worsening heart failure when the monitored heart rate, respiration rate and activity level are outside the predetermined threshold zone; and after determining the patient is experiencing worsening heart failure when the monitored heart rate, respiration rate and activity level are outside the predetermined threshold zone, issuing an alert to indicate that the patient is experiencing worsening heart failure. | 2011-05-05 |
20110105861 | Physiological Monitoring Garment - The present invention is directed to systems and methods for monitoring characteristics of a subject. A system according to an exemplary embodiment of the invention includes a sensor subsystem including at least one respiratory sensor disposed proximate to the subject and configured to detect a respiratory characteristic of the subject, wherein the sensor subsystem is configured to generate and transmit at least one respiratory signal representing the respiratory characteristic, and at least one physiological sensor disposed proximate to the subject and configured to detect a physiological characteristic of the subject, wherein the sensor subsystem is configured to generate and transmit at least one physiological signal representing the physiological characteristic, and a processor subsystem in communication with the sensor subsystem, the processor subsystem being configured to receive at least one of the at least one respiratory signal and the at least one physiological signal. | 2011-05-05 |
20110105862 | DEVICE FOR ACQUIRING AND PROCESSING PHYSIOLOGICAL DATA OF AN ANIMAL OR OF A HUMAN IN THE COURSE OF A PHYSICAL OR MENTAL ACTIVITY - The invention relates to a system allowing the acquisition and processing of data representative of the physical or mental activity and/or of the physiological state of human or animal individuals. This system includes, for each individual, a unique individual electronic box encasing several sensors capable of measuring physical and/or biological quantities related to the physical and/or biological activity of the wearer of the box and of returning information. Each electronic box moreover is provided with an interface for radio communication with a device allowing the management of the data gathered from the individual boxes and management. | 2011-05-05 |
20110105863 | Coupling Loop and Method of Positioning Coupling Loop - A coupling loop or antenna is provided that can be used with a system that determines the resonant frequency of a sensor by adjusting the phase and frequency of an energizing signal until the frequency of the energizing signal matches the resonant frequency of the sensor. In one embodiment orientation features are provided for positioning the coupling loop relative to the sensor to maximize the coupling between the sensor and the coupling loop. | 2011-05-05 |
20110105864 | Pharma-Informatics System - Compositions, systems and methods that allow for the detection of the actual physical delivery of a pharmaceutical agent to a body are provided. Embodiments of the compositions include an identifier and an active agent. The invention finds use in a variety of different applications, including but not limited to, monitoring of therapeutic regimen compliance, tracking the history of pharmaceutical agents, etc. | 2011-05-05 |
20110105865 | DIFFUSE REFLECTANCE SPECTROSCOPY DEVICE FOR QUANTIFYING TISSUE ABSORPTION AND SCATTERING - A diffuse reflectance spectroscopy system for quantifying electromagnetic absorption and scattering in a tissue is provided. Also provided are optical probes and methods for imaging a tissue mass. In some embodiments, the methods include the steps of contacting a tissue mass with an optical probe, wherein the optical probe includes at least one entity for emitting light that interacts with a tissue mass and then is remitted to a collecting entity, for collecting the light that has interacted with the tissue mass, wherein the collecting entity comprises a detector comprising one or more photodiodes; measuring turbid spectral data of the tissue mass using the optical probe; converting the turbid spectral data to at least one of absorption and scattering spectral data via a Monte Carlo algorithm or a diffusion algorithm; and quantifying tissue compositions and scatterer size in a tissue mass using the at least one of absorption and scattering spectral data. | 2011-05-05 |
20110105866 | OPTICAL SENSOR CONFIGURATION FOR RATIOMETRIC CORRECTION OF BLOOD GLUCOSE MEASUREMENT - Embodiments of the invention are directed to an optical sensor for detecting blood glucose. The sensor comprises a chemical indicator system disposed within a gap between the distal end of an optical fiber and an atraumatic tip portion, wherein the optical fiber and atraumatic tip portion are coupled by a coupling member, such as a rod or hypotube or cage that traverses the gap. The sensor further comprises a means for generating and detecting an optical reference signal unrelated to the blood glucose, such that ratiometric correction of blood glucose measurements for artifacts in the optical system is enabled. | 2011-05-05 |
20110105867 | OPTICAL SENSOR FOR DETERMINING THE CONCENTRATION OF AN ANALYTE - A method and apparatus for non-invasively determining a concentration of glucose in a subject using optical excitation and detection is provided. The method includes emitting an exciter beam (B1) to irradiate a portion ( | 2011-05-05 |
20110105868 | METHOD AND DEVICE FOR MEASURING DISSOLVED SUBSTANCES IN HUMAN OR ANIMAL INTRAOCULAR FLUID - The present invention relates to the non-invasive optical measurement of glucose and other dissolved substances in human or animal intraocular fluid. For this purpose, a method and devices for carrying out the method are proposed. The method according to the invention takes advantage of the fact that the wave dependence of optical activity is fundamentally different from corneal birefringence. The optical activity of substances dissolved in the intraocular fluid, such as glucose, lactate, ascorbic acid or amino acids, is scaled as a first approximation with the reciprocal value of the wavelength square. Upon closer review, higher orders must be taken into consideration and effectively an exponent varying from a value of 2 may occur. For glucose, the exponent shall be denoted as 2+x | 2011-05-05 |
20110105869 | Sensor for Internal Monitoring of Tissue O2 and/or pH/CO2 In Vivo - Provided is a durable tissue pH/pCO | 2011-05-05 |
20110105870 | RUTHENIUM PURPLE BIOSENSOR - The invention relates to a biosensor comprising an electrically conductive substrate, with a first layer comprising Ruthenium Purple formed on the substrate, a second layer comprising polyaniline or a derivative thereof comprising one or more non-polar substituents formed on the first layer, and a third layer comprising one or more enzymes trapped within a matrix formed on the second layer. The biosensor is for use in the detection of analytes such as purines and derivatives thereof, particularly in the detection of hypoxanthine. | 2011-05-05 |
20110105871 | MONITORING METHOD AND/OR APPARATUS - A method and apparatus for substance monitoring. One application is an easy to handle continuous glucose monitor using a group of hollow out-of-plane silicon microneedles to sample substances in interstitial fluid from the epidermal skin layer. The glucose of the interstitial fluid permeates a dialysis membrane and reaches a sensor. Using MEMS technology, for example, allows well-established batch fabrication at low cost. | 2011-05-05 |
20110105872 | SYSTEMS AND METHODS FOR APPLICATION TO SKIN AND CONTROL OF ACTUATION, DELIVERY, AND/OR PERCEPTION THEREOF - The present invention generally relates, in certain aspects, to systems and methods for application to the skin, and control of actuation, delivery, and/or perception thereof. For example, certain aspects of the invention are generally directed to devices for delivering to and/or withdrawing fluid or from subjects, e.g., to or from the skin and/or beneath the skin. In one aspect, the delivery and/or withdrawal of fluid is at least partially obscured. For example, the obscuration may be by time, and/or by sensory obscuration (e.g., by providing tactile, olfactory, auditory, and/or visual sensations). Certain aspects of the invention are generally directed to devices able to automatically deliver to and/or withdraw fluid from the skin and/or beneath the skin after activation, e.g., where the fluid is delivered and/or withdrawn without the need for any additional intervention. The devices may be activated by any suitable technique. In other aspects, a device may be contained in a package, and when removed from the package, the device may be constructed and arranged to be able to deliver and/or withdraw fluid when the device is applied to the skin, and in some cases, automatically and/or without any further intervention by the subject or another person. | 2011-05-05 |
20110105873 | Method and Apparatus for Detecting False Hypoglycemic Conditions - Embodiments of the present disclosure include detecting a concurrent occurrence of a decrease in monitored analyte level and a corresponding decrease in monitored on-skin temperature, confirming a presence of an impending hypoglycemic condition, and asserting a notification corresponding to the confirmed impending hypoglycemic condition. Devices, methods, systems and kits incorporating the same are also provided. | 2011-05-05 |
20110105874 | METHOD FOR MEASURING BODY PARAMETERS - A system comprises a capacitive sensing unit for capturing an electrophysiological signal from a body part. The capacitive sensing unit includes a first electrode plate that forms a capacitor with the body part. Motion of the electrode plate with respect to the body part may be detected by a motion sensitive unit mechanically coupled to the capacitive sensing unit. The motion sensitive unit detects motion by self-mixing interferometry. Then, a processing unit rejects the electrophysiological signal if a great displacement of the electrode plate is detected. | 2011-05-05 |
20110105875 | BIOMEDICAL SENSING METHODS EMPLOYING HYDRO-INSENSITIVE ALTERNATING CURRENT RESPONSIVE COMPOSITES - A method is disclosed of detecting a bioelectrical signal from a subject. The method includes the steps of applying a composite material to a subject wherein the composite material includes a polymeric material and a polar material that is substantially dispersed within the polymeric material; coupling monitoring equipment to the second side of the composite material; permitting the polar material within the polymeric material to respond to the bioelectrical signal within the subject; and detecting a responsive electrical signal from the composite material that is representative of the bioelectrical signal. The polar material exhibits molecular compatibility with the polymeric material such that the polar material neither blooms to a surface of the polymeric material nor crystallizes within the polymeric material, and the composite material has a first side for contacting the subject and a second side. | 2011-05-05 |
20110105876 | Subdermal needle electrode cable assembly having movable needle safety cover integral therewith - An apparatus for monitoring neurological and/or neurophysiological signals of a patient has a signal conductor, an electrode, and a safety cover. The signal conductor has a first end portion and a second end portion. The electrode has a first end portion and a second end portion. The first end portion is a skin piercing portion of the electrode and the second end portion is electrically connected to the first end portion of the signal conductor. The safety cover has an electrode shrouding space therein. The electrode shrouding space is configured in a manner allowing the first end portion of the electrode to be positioned within the electrode shrouding space as a result of the safety cover being moved along a length of the signal conductor toward the first end portion of the electrode. | 2011-05-05 |
20110105877 | APPARATUS AND METHOD FOR DETECTING DISCONNECTION OF AN INTRAVASCULAR ACCESS DEVICE - An apparatus and method are disclosed for detecting the disconnection of a vascular access device such as a needle, cannula or catheter from a blood vessel or vascular graft segment. A pair of electrodes is placed in direct contact with fluid or blood in fluid communication with the vascular segment. In one embodiment, the electrodes are incorporated into a pair of connectors connecting arterial and venous catheters to arterial and venous tubes leading to and from an extracorporeal blood flow apparatus. Wires leading from the electrodes to a detecting circuit can be incorporated into a pair of double lumen arterial and venous tubes connecting the blood flow apparatus to the blood vessel or vascular graft. The detecting circuit is configured to provide a low-voltage alternating current signal to the electrodes to measure the electrical resistance between the electrodes, minimizing both the duration and amount of current being delivered. Detection of an increase in electrical resistance between the electrodes exceeding a pre-determined threshold value may be used to indicate a possible disconnection of the vascular access device. | 2011-05-05 |
20110105878 | Electrode For Use With A Template Cap - An electrode attached to the straps of and use with a template cap in making neurophysiological measurements. The electrode is configured to allow the user to quickly and accurately slide an electrode needle at a shallow adjustable angle into the scalp of the patient. The base of each electrode attaches to the cap at locations where measurements are to be made. The base supports a ramp that may be snapped into a clip on the base for storage and then springs resiliently from the clip when released. The electrode needle is carried by a slidable holder secured to the ramp at its slot and is slid forward following that slot when driving the needle down and through a small hole in the base of the electrode to insert it into the patient's scalp at the appropriate depth and angle. | 2011-05-05 |
20110105879 | DIAGNOSIS ASSISTING SYSTEM, COMPUTER READABLE RECORDING MEDIUM HAVING DIAGNOSIS ASSISTING PROGRAM RECORDED THEREON, AND DIAGNOSIS ASSISTING METHOD - A plurality of images for observation in different observation formats and thumbnail images corresponding to each image for observation are generated from volume data obtained for the same subject on different imaging dates/times. A plurality of image windows, which can be switched between an active state and an inactive state, are arranged on a diagnosis screen, and images for observation generated from volume data obtained on specified imaging dates are displayed in each image window. In one embodiment, thumbnail images having the same observation format as an image for observation are displayed in the vicinity of the image for observation within an image window in the active state. | 2011-05-05 |
20110105880 | METHODS FOR IMPROVED SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY USING EXACT AND STABLE REGION OF INTEREST RECONSTRUCTIONS - The present invention provides systems, methods, and devices for improved computed tomography (CT) and, more specifically, to methods for improved single photon computed tomography (SPECT) using exact and stable region of interest (ROI) reconstructions. This technology can be extended across all tomographic modalities. Embodiments provide a method and a system for reconstructing an image from projection data provided by a single photon emission computed tomography scanner comprising: identifying a region of interest in an object; defining an attenuation coefficient and object boundary; computing the generalized Hilbert transform of the data through the defined region of interest and a known subregion; and reconstructing the image with improved temporal resolution at lower radiation doses, wherein the reconstructing comprises performing a reconstruction method that yields an exact and stable reconstruction. Embodiments also provide a method and a system for reconstructing an image from projection data provided by a single photon emission computed tomography scanner comprising: identifying a region of interest in an object; defining an attenuation coefficient and object boundary; and reconstructing the images by minimizing the high order total variation while minimizing the data discrepancy. | 2011-05-05 |
20110105881 | BRAIN DISEASE DIAGNOSIS SYSTEM - An object of the present invention is to perform a more accurate and detailed diagnosis of a brain disease. | 2011-05-05 |
20110105882 | CORRECTING SUBJECT MOTION IN MULTIPLE RESOLUTIONS IN MAGNETIC RESONANCE IMAGING - Systems, methods and articles of manufacture are disclosed for compensating for motion of a subject during an MRI scan of the subject. k-space data may be received from the MRI scan of the subject. A first graphical image may be generated from a first set of data elements from the k-space data. Similarly, a second graphical image may be generated from a second set of data elements from the k-space data. An offset in pixels may be determined by which to translate the second graphical image from the first graphical image to compensate for the motion. The k-space data may be modified at a sub-pixel offset relative to the determined offset. A motion-compensated graphical image of the subject may be generated from the modified k-space data. Doing so reduces the search space evaluated to sharpen images generated from the k-space data. | 2011-05-05 |
20110105883 | REAL TIME MOTION INFORMATION CAPTURE IN AN MRI ENVIRONMENT - Systems, methods and articles of manufacture are disclosed for capturing motion information in a magnetic resonance imaging (MRI) environment. A light sink in the MRI environment may detect light emitted from a plurality of light sources. Each of the plurality of light sources may emit light of a different frequency. Further, each of the plurality of light sources may be located at a different spatial position in the MRI environment. The detected light may be analyzed. A change in spatial position of the light sink may be computed based on the analysis. | 2011-05-05 |
20110105884 | MRI INVOLVING DYNAMIC PROFILE SHARING SUCH AS KEYHOLE AND MOTION CORRECTION - The invention relates to a device and to a method for magnetic resonance imaging (MRI) of a body. It is an object of the invention to provide a technique that enables dynamic profile sharing with significantly reduced motion artifacts. The method of the (such as keyhole) invention comprises the following steps: a) acquiring an MR data set ( | 2011-05-05 |
20110105885 | Methods of Predicting Musculoskeletal Disease - This invention is directed to methods of predicting bone or joint disease in a subject. The invention is also directed to methods of determining the effect of a candidate agent on any subject's risk of developing bone or joint disease. | 2011-05-05 |
20110105886 | DIFFUSION-BASED MAGNETIC RESONANCE METHODS FOR CHARACTERIZING BONE STRUCTURE - A method of in vitro or in vivo nuclear magnetic resonance and/or magnetic resonance imaging, to determine bone properties by measuring the effects of molecular diffusion inside the bone specimen to derive parameters that are related to the structure of the trabecular bones. The method is a non-invasive probe that provides topological information on trabecular bone without requiring a full high-resolution image of its structure, and is compatible with clinical use. | 2011-05-05 |
20110105887 | REVERSE DATA RECONSTRUCTION FOR OPTIMAL TIME SAMPLING OF COUNTS IN PHYSIOLOGICAL LIST-MODE NUCLEAR IMAGING - A diagnostic imaging device includes detector elements ( | 2011-05-05 |
20110105888 | MAGNETIC RESONANCE IMAGING APPARATUS AND METHOD OF DETERMINING EXECUTION ORDER - It has an object to suppress reduction of an examination efficiency caused by limitation of SAR (specific absorption rate) to the minimum level in an examination that plural imaging sequences containing different imaging sequences are consecutively executed. In consideration of the time variation of time average SAR value in the overall examination, the order of executing the imaging sequences is determined so that the SAR value falls within a predetermined range and the waiting time between imaging sequences is minimum. The determination is performed by calculating a waiting time of each of all conceivable execution orders and selecting an execution order having the minimum waiting time. | 2011-05-05 |
20110105889 | NANOPARTICLE LABELING AND SYSTEM USING NANOPARTICLE LABELING - A nanoparticle labeling which is simultaneously usable in the combination of X-ray imaging with optical imaging and the combination of X-ray imaging and optical imaging with magnetic resonance imaging characterized by comprising core/shell type semiconductor nanoparticles having an average shell thickness of 0.1 nm or more but not more than 10.0 nm together with an X-ray sensitive material for the former combination, and core/shell type semiconductor nanoparticles having an average shell thickness of 0.1 nm or more but not more than 10.0 nm together with an X-ray sensitive material and magnetic particles for the latter combination. | 2011-05-05 |
20110105890 | MRI OPERATING METHOD - A magnetic-resonance imager is operated by, within the time of a R-R interval of the heart, carrying out a preparation sequence for suppressing signal contributions from the blood is carried out, in particular by a saturation sequence. At least the first refocusing pulse is generated simultaneously with a layer-selective gradient magnetic field that acts orthogonally to the layer-selective gradient magnetic field at the time of the generation of the RF excitation pulse. In addition the measuring value acquisition and image generation takes place by means of subsampling the data space and/or partially sampling the data space. | 2011-05-05 |