| 18th week of 2011 patent applcation highlights part 44 |
| Patent application number | Title | Published |
|---|
| 20110103977 | Control Process for a Piezoelectric Pump of an Electric Household Appliance and an Electric Household Appliance Employing Such a Process - Control process for a piezoelectric pump ( | 2011-05-05 |
| 20110103978 | TURBINE WITH IMPROVED SOUND REDUCTION - The present disclosure generally relates to a turbine for a fluid delivery system and more specifically, but not by limitation, to a portable air turbine for a fluid delivery system having improved sound reduction. In one exemplary embodiment, a portable turbine apparatus is provided and includes a motor and a turbine configured to be driven by the motor for providing pressurized air to an outlet. A first inlet airflow path delivers air to the motor. A first silencer component having sound absorptive material is positioned along the first inlet airflow path and includes at least one orifice formed therethrough for the first inlet airflow path, the at least one orifice having a cross-sectional area of at least 0.01 square inches. A second inlet airflow path delivers air to the turbine. A second silencer component having sound absorptive material is positioned along the second inlet airflow path and includes at least one orifice formed therethrough for the second inlet airflow path, the at least one orifice having a cross-sectional area of at least 0.01 square inches. | 2011-05-05 |
| 20110103979 | ELECTRIC COMPRESSOR - The present invention provides an electric compressor which enables prescribed insulation performance to be ensured even if poly alkyl glycol type lubricating oils are used. The electric compressor is provided with an insulating cover which is provided so as to cover a connection section between a terminal body and a lead wire on the motor side, and on a surface on the side of a first insulating member of the insulating cover, there is provided a cutoff section which cuts off a leakage path by abutting against the first insulating member, whereby the leakage path between the first insulating member and the insulating cover is cut off. | 2011-05-05 |
| 20110103980 | Household Electric Appliance Having a Piezoelectric Pump - The invention relates to an electric household appliance comprising a pump having a pumping chamber ( | 2011-05-05 |
| 20110103981 | Heat Dissipating Fan - A heat dissipating fan includes a housing having an air inlet and air outlet between which an air passageway is formed. A fixed seat is provided in the air passageway and includes first positioning holes. A magnetically conductive first casing includes a first outer wall, an extended wall extending radially outward from an end of the first outer wall and having second positioning holes aligned with the first positioning holes, and a first support on the other end of the first outer wall. A second casing is coupled to an inner peripheral of the extended wall of the first casing. A motor mounted in the first and second casings includes a stator and a circuit board electrically connected to the stator. | 2011-05-05 |
| 20110103982 | Ceiling fan - The invention is an improved ceiling fan for cleaning polluted air. A fan rod ( | 2011-05-05 |
| 20110103983 | COOLANT COMPRESSOR - A coolant compressor ( | 2011-05-05 |
| 20110103984 | VALVE AND DIAPHRAGM FOR A PUMP - A diaphragm pump ( | 2011-05-05 |
| 20110103985 | FUEL PUMP WITH AN IMPROVED DAMPING DEVICE FOR A DIRECT INJECTION SYSTEM - A fuel pump for a direct injection system having: at least one pumping chamber; a piston which is mounted sliding inside the pumping chamber in order to vary cyclically the volume of the pumping chamber; an intake duct connected to the pumping chamber and regulated by an inlet valve; a delivery duct connected to the pumping chamber and regulated by a one-way delivery valve which allows exclusively a fuel flow outgoing from the pumping chamber; and a damping device, which is placed along the intake duct upstream of the inlet valve, and comprises at least one elastically deformable damping body that has internally a closed chamber filled with pressurized gas and composed of two metal plates cup shaped and welded together at their annular edges by an annular weld without interruptions. | 2011-05-05 |
| 20110103986 | COMBINED BEARING AND ROTARY MACHINE - A highly reliable combined bearing capable of achieving equal and sufficient lubrication of a plurality of rolling bearings with a simple and compact structure is provided. The combined bearing includes a first rolling bearing and a second rolling bearing which are in contact with each other and arranged on the same axis; and a lubricating-oil inlet for introducing a lubricating oil into an inner space formed between the first rolling bearing and the second rolling bearing, the lubricating-oil inlet being provided on at least one of an outer ring of the first rolling bearing and an outer ring of the second rolling bearing. | 2011-05-05 |
| 20110103987 | PUMP SYSTEM - The present invention provides a pump system comprising a bearing housing coupled to a pump liner, the pump liner defining a fluid conduit, the pump liner comprising a fluid inlet and a fluid outlet; and at least one rotor having a first rotor portion and a second rotor portion, the first rotor portion being disposed within the fluid conduit and the second rotor portion being disposed within the bearing housing; the first rotor portion comprising a first conveying stage adjacent to the bearing housing, and a second conveying stage adjacent to the first conveying stage, the first and second conveying stages being configured to convey a fluid, the first conveying stage being configured to convey the fluid from the bearing housing into the fluid conduit. The new pump systems rely on a dynamic restriction to reduce the need for mechanical seals between bearing housings and raw process fluid. | 2011-05-05 |
| 20110103988 | COMPRESSOR HAVING CAPACITY MODULATION SYSTEM - A compressor may include a housing and first and second scroll members supported within the housing, each having an end plate with a spiral wrap extending therefrom and meshingly engaged with the other to form a series of compression pockets operating at an intermediate fluid pressure between a suction pressure and a discharge pressure. A first passage in communication with one of the compression pockets extends from a first side of the first end plate to a second side of the first end plate generally opposite the first side. A modulation plate overlies the second side of the first scroll member for radial displacement between first and second positions. The modulation plate isolates the first passage from communication with a suction pressure region of the compressor when in the first position and provides communication between the first passage and the suction pressure region when in the second position. | 2011-05-05 |
| 20110103989 | Progressing Cavity Pump Rubber Reinforcement Device for Rotor Alignment - A progressing cavity pump assembly utilizes a reinforced upper section of the stator rubber helix. The pump stator is located at the end of a string of tubing. The reinforced upper section of the stator rubber helix is strong enough, whether reinforced by mechanical means or by strengthening the rubber matrix chemically, so as not to allow the passage of a stop located above or on the top of the pump rotor. The rotor is lowered on a string of rods until the stop above or on top of the rotor lands onto the reinforced upper section of the stator rubber helix. The rotor is then repositioned away from the stator helix a predetermined distance before pump operation begins with rod string rotation. | 2011-05-05 |
| 20110103990 | SCROLL COMPRESSOR - A scroll compressor is constructed by combining a stationary scroll and an orbiting scroll formed by erecting a scroll-shape wrap upright on a base plate meshing with each other. A scroll member constructing the stationary scroll or the orbiting scroll is constructed of an inner layer member | 2011-05-05 |
| 20110103991 | Scroll fluid machine - A fixed scroll board | 2011-05-05 |
| 20110103992 | GEAR PUMPS AND METHODS FOR USING GEAR PUMPS - Gear pumps and methods of using the gear pumps are provided. In general embodiments, the pumps comprise a gear housing defining a passage and having an inlet and an outlet and one or more gears contained within the gear housing. The gears can comprise corresponding bearings that are movably engaged with the gear. The bearings are separated from the passage of the gear housing by one or more seals. The bearings can be contained within a bearing housing attached to the gear housing. | 2011-05-05 |
| 20110103993 | GEAR WHEEL WITH PROFILE CAPABLE OF MESHING WITH SEMI-ENCAPSULATION IN A GEARED HYDRAULIC APPARATUS - A geared hydraulic apparatus comprises a pair of gear wheels which mesh with each other with semi-encapsulation. Each gear wheel has a plurality of teeth with a profile which falls within a band of tolerance of ±15, more preferably ±20, and even more preferably ±30 with respect to the height of the tooth, with respect to a profile similar to a profile defined by a predetermined spline function passing through a plurality of nodal points having pre-established coordinates {X,Y} with origin on the rotational axis. | 2011-05-05 |
| 20110103994 | METHOD AND APPARATUS FOR PRODUCING A LIGHTWEIGHT METAL ALLOY - A method of forming a metal alloy from a powder composition comprising first particles in a range of approximately 20-90% by weight of the powder composition, the remainder of the powder composition comprising approximately 95% by weight of second particles and 5% by weight of third particles, wherein the method includes the step of using rapid thermal processing (RTP) to sinter the powder composition. | 2011-05-05 |
| 20110103995 | IRON-BASED PRE-ALLOYED POWDER - A pre-alloyed iron-based powder is provided including small amounts of alloying elements which make possible a cost efficient manufacture of sintered parts. The pre-alloyed iron-based powder comprises 0.2-1% by weight of Cr, 0.05-0.3% by weight of Mo, 0.1-1% by weight of Ni, 0.09-0.3% by weight of Mn, 0.01% by weight or less of C, less than 0.25% by weight of O, and less than 1% by weight of inevitable impurities, the balance being iron. | 2011-05-05 |
| 20110103996 | CONTINUOUS CAST SLAB AND PRODUCING METHOD THEREFOR - A continuous cast slab includes the following component: by mass %, C: 0.01˜0.3%, Si: 0.05˜0.5%, Mn: 0.4˜2%, P: 0.03% or less, S: 0.03 or less, Al: 0.005˜0.03%, Ni: 0.2˜2%, O: 0.006% or less, and N: 0.006% or less; wherein the balance is composed of Fe and inevitable impurities; wherein a structure in steel in a region within at least 2 mm from a broad surface is composed of ferrite and pearlite and a equivalent circular diameter of ferrite grains in the region is equal to or shorter than 30 μm. | 2011-05-05 |
| 20110103997 | ATTRITED TITANIUM POWDER - A method of increasing the apparent density of agglomerated ligmental titanium or titanium alloy powder produced by the subsurface reduction of titanium tetrachloride vapor or a mixture of titanium tetrachloride and other halide vapors in a flowing stream of alkali or alkaline earth metal or mixtures thereof having a first apparent density after distillation is disclosed. The agglomerated ligmental titanium or titanium alloy powder is introduced into an attriting system wherein the agglomerated ligmental titanium or titanium alloy powder is attrited until the powder becomes more spherical than ligmental and the first apparent density is increased by a factor of from about 3 to about 8. Inert atmosphere may be used to prevent unwanted oxygen contamination. | 2011-05-05 |
| 20110103998 | Production of Nickel - A method of producing a nickel product (including nickel alloy products and products such as nickel matte) from a nickel intermediate product is disclosed. The method comprises smelting a dried nickel intermediate product in a molten bath-based smelter and forming a molten pool containing a molten metal and a slag, with the molten metal being the nickel product. Intermediate and end products produced by the method are also disclosed. | 2011-05-05 |
| 20110103999 | METAL COATING FORMING METHOD AND AEROSPACE STRUCTURAL MEMBER - Provided are a method for forming a metal coating at high speed by using a simple cold spray apparatus, and an aerospace structural member on which a metal coating is formed by the cold spray method. In the metal coating forming method, nonspherical heteromorphous particles made of metal are projected onto a base material surface by the cold spray method to form a metal coating on the base material surface. | 2011-05-05 |
| 20110104000 | Lead-Free, Bismuth-Free Free-Cutting Silicon Brass Alloy - The present invention supplies a lead-free, bismuth-free free-cutting silicon brass alloy with high zinc which preferably comprises 35.0 to 42.0 wt % Zn, 0.1 to 1.5 wt % Si, 0.03 to 0.3 wt % Al, 0.01 to 0.36 wt % P, 0.01 to 0.1 wt % Ti, 0.001 to 0.05 wt % rare earth metals selected from the group consisting of La and Ce, 0.05 to 0.5 wt % Sn, and/or 0.05 to 0.2 wt % Ni, and the balance being Cu and unavoidable impurities. In yet another embodiment, the alloy may be boron-free. The invented alloy is excellent in castability, weldability, cuttability, electroplating properties, corrosion resistance, mechanical properties. The alloy is especially applicable in castings which need cutting and welding under low pressure die casting, such as castings for faucet bodies in the water supply system. The alloy is also suitable for use in components which are produced from casting ingots by die forging. | 2011-05-05 |
| 20110104001 | Aluminum alloy sheet for lithographic printing plate - An aluminum alloy sheet for a lithographic printing plate includes 0.03 to 0.15% (mass %, hereinafter the same) of Si, 0.2 to 0.7% of Fe, 0.05 to 0.5% of Mg, 0.003 to 0.05% of 11, and 30 to 300 ppm of Ga, with the balance being aluminum and inevitable impurities, a surface area of the aluminum alloy sheet having an average recrystallized grain size of 50 μm or less in a direction perpendicular to a rolling direction, an Mg concentration that is higher than the average Mg concentration by a factor of 5 to 50, and a Ga concentration that is higher than the average Ga concentration by a factor of 2 to 20, the surface area being an area up to a depth of 0.2 μm from the surface of the aluminum alloy sheet. | 2011-05-05 |
| 20110104002 | METHOD AND USE OF PROVIDING PHOTOCATALYTIC ACTIVITY - Disclosed is a method of providing photocatalytic activity. Nanoparticulate matter comprising a strontium titanate ferrite of the general formula SrTi1-xFexO3- is provided, in which x is any value from 0 to 1. The nanoparticulate matter is exposed to electromagnetic radiation of a wavelength from about 380 nm to about 800 nm. | 2011-05-05 |
| 20110104003 | METHODS FOR MAKING OXIDATION RESISTANT POLYMERIC MATERIAL - The present invention relates to methods for making oxidation resistant medical devices that comprise polymeric materials, for example, ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making antioxidant-doped medical implants, for example, doping of medical devices containing cross-linked UHMWPE with vitamin E by diffusion and materials used therein. | 2011-05-05 |
| 20110104004 | SPORT BALL SANITIZER - An apparatus for sanitizing a sport ball includes a container that receives the sport ball and at least one germicidal light source coupled to the container. The at least one germicidal light source emits germicidal wavelength light onto the sport ball within the container during operation of the apparatus. Alternatively, the apparatus includes a germicidal light-transparent receptacle that receives the sport ball and a plurality of germicidal light sources coupled to the germicidal light-transparent receptacle. The plurality of germicidal light sources emit germicidal wavelength light, at least in part through the germicidal light-transparent receptacle, onto each location on the surface of the ball for at least a predetermined intensity-time. | 2011-05-05 |
| 20110104005 | METHOD FOR DISINFECTING A ROOM AND OBJECTS CONTAINED THEREIN AND DISINFECTING COMPOSITION - The present invention relates to a method for disinfecting a room and the objects that may be contained therein, or surfaces in general, including the following steps: (a) determining the volume of the room to be disinfected; (b) as a function of the value determined in step a) above, determining a volumetric concentration of an aqueous disinfecting solution delivered into the room in the form of a dry mist required for obtaining a predefined level of disinfection, said disinfecting solution comprising hydrogen peroxide and silver ions (Ag+); (c) delivering into the room said aqueous disinfecting solution in the form of a dry mist until the desired volumetric concentration is achieved; (d) keeping said aqueous disinfecting solution in the form of a dry mist in contact with the room and with the objects that may be contained therein for a predefined time, so as to achieve a desired level of disinfection. A second object of the present invention consists in a disinfecting solution that is particularly suitable for implementing said method. | 2011-05-05 |
| 20110104006 | Method for Sterilizing Powder or Grain and Sterilizing Apparatus Employing the Same - [Problem to be solved] To provide a method for sterilizing powder or grain by which the heating time is a minimum required time to reduce thermal degradation of the quality of the powder or grain while securing sufficient sterilization effect, and a sterilizing apparatus employing the method. | 2011-05-05 |
| 20110104007 | AUTOMATIC ANALYZING DEVICE - A reaction solution is mixed in a short period of time with excellent stir efficiency. A stir rod | 2011-05-05 |
| 20110104008 | TWO DIMENSIONAL SAMPLE HANDLER - A method for positioning a sample in a diagnostic analyzer includes: providing two or more sample carriers on a conveyor; providing a fixed registration element for each sample carrier at predetermined locations along the conveyor; providing a flexure device positioned between the sample carrier and the conveyor; advancing the sample carrier beyond the fixed registration elements; reversing the conveyor direction to back at least one of the sample carriers into contact with its corresponding registration elements; continuing to reverse the conveyor until all sample carriers are in contact with their respective registration elements; whereby the flexure elements of the sample carriers in contact with the respective registration elements will deform as the conveyor reverses to allow all sample carriers to contact their respective registration elements, thereby providing a known position of the sample carrier. The flexure device includes: first and second legs forming a inverted U-shape; a third leg which extends away from the top of the inverted U-shape; and a fourth leg which extends down the center of the U in the direction of the ends of the U. | 2011-05-05 |
| 20110104009 | CLINICAL EXAMINATION DISK, DISK PACK, AND CLINICAL EXAMINATION DEVICE - A clinical examination disk according to the invention includes a disk body in a disk form, and at least one cell formed in the disk body, wherein the cell comprises a specimen reservoir formed in the disk body and having a specimen injecting port, a reaction tank formed in the disk body so as to position nearer to the outer circumference of the body than a position of the specimen reservoir, and holding a reagent which is reactive with the specimen and is beforehand gelatinized, a first narrow tube formed in the disk body, and communicating to the specimen reservoir and the reaction tank, and a second narrow tube formed in the disk body, and having one end connected to the reaction tank and the other end made open. | 2011-05-05 |
| 20110104010 | BINDING REAGENT SYSTEM FOR HOMOGENEOUS IMMUNOASSAYS FOR MULTIPLE ALLERGENS - A homogeneous immunoassay method and system for quantitative determination of total immunoglobulin E and specific antibody levels to a plurality of allergens, in which a relatively small sampling of blood is required. The method utilizes relatively small microparticles in aqueous suspension. The immunoassay procedure is an immunometric sandwich procedure preferably utilizing biotin-streptavidin signal amplification techniques and R-phycoerytherin fluorescent labels. | 2011-05-05 |
| 20110104011 | Gas Reaction Device Having Four Reaction States - The present disclosure provides a gas reaction device. Reactions are happened on a fixed bed and/or a slurry bed in four reaction states. Thus, by using the four reaction states, reactions are thoroughly completed with the same catalyst. Or, different reactions are completed with different catalysts for different purposes. | 2011-05-05 |
| 20110104012 | Method and Apparatus for Use of Reacted Hydrogen Peroxide Compounds in Industrial Process Waters - Methods and apparatuses are described for contacting an oxidizing solution such as an aqueous hydrogen peroxide composition of hydrogen peroxide and at least one additive that catalyzes the decomposition of the hydrogen peroxide into hydroxyl radicals with an atmospheric effluent containing odorous and/or noxious components. These components are absorbed by the aqueous hydrogen peroxide composition to produce an atmospheric effluent having reduced amounts of the odorous and/or noxious components. Various methods are described for adding the hydrogen peroxide and the decomposition additive. | 2011-05-05 |
| 20110104013 | METHOD FOR PRODUCING PHOTOCATALYTIC MATERIALS AND MATERIALS AND APPARATUS THEREWITH - Methods for the production of photocatalytic materials and coated substrate materials are provided according to the invention. A process for forming a photocatalytic coating on a substrate is provided. The photocatalytic coating includes titanium oxide on a titanium substrate for example. The photocatalytic coated substrate may be used in a device for treating contaminated fluids including water, air and mixtures thereof. | 2011-05-05 |
| 20110104014 | CIRCULATING FLUIDIZED BED GASIFICATION FURNACE - A circulating fluidized bed gasification furnace has a combustion furnace | 2011-05-05 |
| 20110104015 | APC PROCESS PARAMETER ESTIMATION - A virtual analyzer is provided to estimate either an attribute of a reactant applied during performance of, or an amount of a reactant exhausted by, a process having multiple process parameters (MPPs) that is performed to control an amount of a pollutant emitted into the air. The virtual analyzer includes an interface which receives signals corresponding to attributes of the MPPs. If the process is a wet flue gas desulfurization (WFGD) process, the signals include a signal corresponding to a measured pH level of the applied reactant. If the process is a selective catalytic reduction (SCR) process, the signals include a signal corresponding to a measured amount of the reactant exhausted by the process. | 2011-05-05 |
| 20110104016 | HONEYCOMB BODY WITH CONNECTION-FREE REGION, EXHAUST-GAS PURIFICATION UNIT AND MOTOR VEHICLE - A honeycomb body includes at least a housing and a honeycomb structure having a plurality of channels. The honeycomb structure is formed of at least one at least partially structured metallic layer that forms connecting points fixing the honeycomb structure. At most 20% of inner contact points in a cross section of the honeycomb structure form a connection point, and the connection points are disposed at a distance from each other in such a way that respective connection-free regions of the same size surround each of the connection points. An exhaust-gas purification unit and a motor vehicle are also provided. | 2011-05-05 |
| 20110104017 | PORTABLE UV WATER TREATMENT SYSTEM - A portable water purification system and method of operation of the system is disclosed that may comprise a container defining a water purification chamber; a plurality of UV generating light sources distributed in the purification chamber of the container; and a portable power source electrically connected to the light sources, and adapted to convert kinetic energy to electrical energy to provide to the light sources. The portable power source may be adapted to be driven by human motive power to provide the kinetic energy. The purification system may comprise a filling opening to the container; and a filter intermediate the filling opening and the chamber adapted to remove turbidity from the water entering the water purification chamber through the filling opening. The portable power source may comprise a hand-cranked electrical generator. The UV light sources may produce UV light in a wavelength band selected to effectively deactivate all harmful biological water contaminants, and produce UV light in a dosage sufficient to effectively deactivate all harmful biological water contaminants. | 2011-05-05 |
| 20110104018 | DEVICE FOR COOLING AND DISTRIBUTING MIXED CHARGES ON FIXED CATALYST BEDS - This invention relates to a device for cooling and distributing mixed charges on fixed catalyst beds for use in the cooling zone of descending flow reactors which comprises a flat tray fitted with collector and distributor tubes for liquid superimposed upon and connected to another flat tray of similar design to the upper tray. The device, which is of smaller size in comparison with other commercially available devices, is extremely simple to install industrially and compact, and has as its main characteristic the efficiency with which it promotes reduction of the temperature of the reaction medium when it receives the cooling fluid within the catalytic reactor. | 2011-05-05 |
| 20110104019 | Polyester Production System Employing an Unagitated Esterification Reactor - A polyester production system employing a vertically elongated esterification reactor. The esterification reactor of the present invention is an improvement over conventional CSTR esterification reactors because, for example, in one embodiment, the reactor requires little or no mechanical agitation. Further, in one embodiment, the positioning of the inlets and outlets of the reactor provides improved operational performance and flexibility over CSTRs of the prior art. | 2011-05-05 |
| 20110104020 | SYSTEM FOR EXTERNALLY HOLDING A CATALYST BED IN RADIAL-FLOW REACTOR - The invention relates to a system for externally holding a catalyst bed in a radial flow catalytic reactor, comprising a plurality of hollow longitudinal duct elements ( | 2011-05-05 |
| 20110104021 | Hydrogen Membrane Separator - The present application is directed to a hydrophobic membrane assembly ( | 2011-05-05 |
| 20110104022 | POWDER DISPENSING ASSEMBLY FOR A WASTE CONTAINER - A powder dispenser for a waste disposal system includes a mounting portion that is adapted to be secured to a waste disposal unit, and a container defining an interior space in which a powder such as sodium bicarbonate may be stored. The container is releasably mounted to the underside of a hinged lid member of the waste disposal unit. A directional dispensing system is provided for dispensing powder from the container into a targeted portion of the waste disposal system. The directional dispensing system is constructed and arranged to concentrate initial dispersal of the powder to a single side of the container and includes a dispensing orifice. The dispensing orifice is preferably oriented to limit initial dispersal of the powder within a defined angular range with respect to the longitudinal axis of the lid member, and is spaced axially and laterally with respect to the waste disposal unit at distances that facilitate distribution of the powder to desired targeted portions of the waste disposal unit. The container and waste disposal unit also define a venting path so that the powder within the container can also absorb odors within the waste disposal unit. | 2011-05-05 |
| 20110104023 | HUMIDITY INDICATOR AND METHOD FOR PRODUCING THE SAME - A humidity indicator including a coloration composition, which contains a deliquescent material, supported on a porous base material, wherein the adhesion of the coloration composition, which has been once printed and thus adhered to the base material, to a member or the like of a printer is inhibited in a production process to thereby reduce printing errors and the maintenance frequency of the printer. Furthermore, blocking which occurs in stacking multiple humidity indicators can be prevented. Beads not reacting with the constituting components of the coloration composition are dispersed into the coloration composition to form convex portions. Further, the coloration composition is coated with a top coat layer including beads dispersed in a resin. | 2011-05-05 |
| 20110104024 | MICROVALVE AND SEALING DEVICE FOR USE IN A MICROFLUIDICS SYSTEM, AND METHOD FOR THE PRODUCTION THEREOF - A microvalve for controlling fluid flows, and a sealing device for sealing cavities in a microfluidic system, particularly in a lab-on-a-chip system, and a method for the production thereof. A sealing surface of a valve body, or a sealing element, respectively, rests on a sealing surface of a substrate and is pressed against the sealing surface of the substrate in a fluid-tight manner by means of a clamping element. The clamping element and/or the valve body, or the sealing element, respectively, are at least partially elastic. | 2011-05-05 |
| 20110104025 | METHOD FOR PRODUCING RECONFIGURABLE MICROCHANNELS - A microfluidic device, including a microfluidic network, including: a) two parallel plates each including one or more electrodes, b) at least one channel, arranged between the two plates, made from a material obtained by solidification or hardening of a material of a first fluid, and c) a mechanism varying a physical parameter of the material constituting walls of the channel so as to cause the material to pass at least from the liquid state to the solid state. | 2011-05-05 |
| 20110104026 | APPARATUS FOR EXTRACTING BIOCHEMICAL MATERIALS FROM BIOLOGICAL SAMPLES - Disclosed herein is a single-use extraction apparatus which is disposed of after use. The extraction apparatus includes a tube plate having a tube therein, and a column plate. The column plate is detachably coupled to the tube plate, and includes a column which corresponds to the tube of the tube plate. A filter is provided in the column and made of a material which adsorbs or desorbs biochemical materials included in biological samples. A hollow suction port is provided at a predetermined position of the column plate to connect to a vacuum pump. The apparatus is capable of extracting biochemical materials from biological samples by using vacuum pressure without centrifugal separation, thus realizing a simple, convenient and rapid extracting operation, and has a small size so that it rapidly reaches desired vacuum pressure and uniform vacuum pressure can act on the column. | 2011-05-05 |
| 20110104027 | CALIBRATION PROCEDURES AND DEVICES FOR INVESTIGATION BIOLOGICAL SYSTEMS - Use of calibrant in extraction phase is described for quantification of components of interest in samples in laboratory application as well as in on-site monitoring. This approach is particularly useful for in-vivo investigation of living system. | 2011-05-05 |
| 20110104028 | INTEGRAL-TYPE REACTION CARTRIDGE - An integral-type reaction cartridge includes a plurality of reaction containers and at least a separation container. The plural reaction containers and the separation container are integrally formed of plastic and lined along a first direction. The separation container has a first end, a second end opposing the first end, and a hollow accommodating space between the first and second ends, wherein the first end is an open end, the second end is a closed end, and the accommodating space tapers from the first end to the second end. The accommodating space has a first side and a second side along the first direction, as well as a third side and a fourth side along a second direction perpendicular to the first direction. Near the second end, at least one of the first side and the second side has a greater slope than the third side and the fourth side. | 2011-05-05 |
| 20110104029 | PHOTOCATALYTIC MATERIAL FOR SPLITTING OXIDES OF CARBON - An embodiment relates to a photocatalytic composite material comprising (a) a first component that generates a photoexcited electron and has at least a certain minimum bandgap to absorb visible light and a structure that substantially prevents the recombination of the photoexcited electron and a hole; (b) a second component that adsorbs/absorbs an oxide of carbon; and (c) a third component that splits the oxide of carbon into carbon and oxygen using the photoexcited electron. | 2011-05-05 |
| 20110104030 | COMPOSITION AND METHOD FOR REMOVAL OF CARBONYL SULFIDE FROM ACID GAS CONTAINING SAME - Novel solvent composition for selective removal of COS from a gas stream containing same, said composition comprising
| 2011-05-05 |
| 20110104031 | METHODS AND APPARATUS FOR RESIDUAL MATERIAL MANAGEMENT - Residual impurity reduction methods and apparatus are provided. A method comprises conducting a gaseous stream through an unlined portion of a pipe, wherein the gaseous stream comprises sodium and wherein the unlined portion of the pipe is at least about eighteen inches long, injecting a neutralizing agent into the gaseous stream at an injection point, wherein the injection point is located at a point where the sodium is in at least a partially condensed state. The gaseous stream is conducted through a heated portion of a pipe and a cooled portion of a pipe. In addition, methods and apparatus may include a trap system for use with a carbonization furnace. | 2011-05-05 |
| 20110104032 | METHOD OF PRODUCING SULFUR TETRAFLUORIDE FROM URANIUM TETRAFLUORIDE - A method for converting depleted uranium tetrafluoride (UF | 2011-05-05 |
| 20110104033 | METHODS OF MAKING TITANIUM DIBORIDE POWDERS - The present disclosure is directed towards methods of making titanium diboride products in various sizes. An aspect of the method provides (a) selecting a target average particle size for a target titanium diboride product; (b) selecting at least one processing variable from the group consisting of: an amount of sulfur, an inert gas flow rate, a soak time, and a reaction temperature; (c) selecting a condition of the processing variable based upon the target average particle size; and (d) producing an actual titanium diboride product having an actual average particle size using the at least one processing variable, wherein due to the at least one processing variable, the actual average particle size corresponds to the target average particle size. | 2011-05-05 |
| 20110104034 | Hydride compounds - This invention is directed to compositions of matter comprising a hydride ion having a binding energy greater than about 0.8 eV. The claimed hydride ions may be combined with cations, including a proton, to form novel hydrides. | 2011-05-05 |
| 20110104035 | METHOD FOR PRODUCING POLYCRYSTALLINE SILICON - The invention relates to a polycrystalline silicon production method. The inventive method involves supplying a gas mixture based on a silicon-containing gas to a reduction reactor via a tube system and precipitating silicon on heated surfaces in such a way that an effluent gas mixture is formed. The silicon precipitation process is simultaneously carried out in at least two reactors which are connected in series by the tube system for transporting the gas mixture. Then, the gas mixture used for the operation of all the reactors is supplied at entry into the first reactor and is continuously transmitted through all the connected in series reactors. | 2011-05-05 |
| 20110104036 | METHOD AND APPARATUS FOR PURIFYING METALLURGICAL GRADE SILICON BY DIRECTIONAL SOLIDIFICATION AND FOR OBTAINING SILICON INGOTS FOR PHOTOVOLTAIC USE - A method and an apparatus for purification of metallurgical grade silicon by directional solidification and for obtaining silicon ingots for photovoltaic use. The method comprises a preheating step, up to a temperature that is higher than the melting point of silicon, of a quartz crucible ( | 2011-05-05 |
| 20110104037 | PROCESS FOR THE PRODUCTION OF AMMONIA - Process for the production of ammonia from a hydrocarbon feedstock all steam produced in the waste heat boilers of the reforming and ammonia section of the plant is superheated in one or more steam superheaters located downstream the ammonia converter in the ammonia section of the plant. There is no need for steam superheater (s) in the reforming section of the plant to cool the synthesis gas. A steam superheater for use in the process is also provided. The superheater comprises two compartments in which the first and second compartments are connected in series with respect to the steam flow and in parallel with respect to the process gas flow. | 2011-05-05 |
| 20110104038 | METHOD OF MAKING PURE SALT FROM FRAC-WATER/WASTEWATER - The present invention relates to a method for making pure salt comprises recapturing post-drilling flowback water from hydro-fracturing; removing oil from the flowback water; filtering the flowback water using an ultra filter with a pore size of about 0.1 microns or less to remove solid particulates and large organic molecules, such as benzene, ethylbenzene, toluene, and xylene, from the water; concentrating the flowback water to produce a brine that contains from about 15 wt % to about 40 wt % of salt relative to the total weight of the flowback brine; performing one or more chemical precipitation process using an effective amount of reagents to precipitate out the desired high quality commercial products, such as, barium sulfate, strontium carbonate, calcium carbonate; and crystallizing the chemically treated and concentrated flowback brine to produce greater than 99.5% pure salt products, such as sodium and calcium chloride. | 2011-05-05 |
| 20110104039 | PROCESS FOR PREPARING CATALYSTS INVOLVING THE REGENERATION OF METAL CARBONATE PRECIPITANTS - A process for manufacturing a catalyst composition includes the steps of
| 2011-05-05 |
| 20110104040 | SIMPLE, EFFECTIVE AND SCALABLE PROCESS FOR MAKING CARBON NANOTUBES - A simple, effective and scalable method for fabricating carbon nanotubes. The method has two simple steps: (a) producing the carbon precursors (i.e., nanotubes of conducting polymer) in water solution via a soft template method involving a fibrillar complex and (b) carbonizing the carbon precursors (i.e. the nanotubes of the conducting polymer) at a temperature between 900-2200° C. in a nitrogen atmosphere or under a vacuum condition. | 2011-05-05 |
| 20110104041 | METHODS AND SYSTEMS FOR HCN REMOVAL - Hydrogen cyanide removal during transformation of a carbon fiber precursor into carbon fiber is provided. The method may comprise heating a carbon fiber body precursor at a substantially atmospheric pressure to above about 1200° C. in a furnace in a first stage, expelling a stream of effluent gas outside the furnace, wherein the stream of effluent gas comprises a cyanide, thermally oxidizing the cyanide during the first stage, and heating the carbon fiber body precursor to a temperature of between about 1600° C. and about 2200° C. in a second stage. | 2011-05-05 |
| 20110104042 | CONVECTIVE DISSOLUTION OF SALTS IN SITU PONDS - A unique method of convective dissolution of salts from in situ ponds by trenching salt beds, introducing dissolution waters to promote convective dissolution, pumping out the saturated solution from the pond bottom, and introducing additional dissolution waters. | 2011-05-05 |
| 20110104043 | INSTRUMENT AND PROCESS FOR NANOPARTICLES PRODUCTION IN CONTINUOUS FLOW MODE - The subject of the invention is the ( | 2011-05-05 |
| 20110104044 | DIRECT SYNTHESIS OF AQUEOUS HYDROGEN PEROXIDE SOLUTION AT THE SITE OF A PAPER MILL - The invention relates to a plant for producing hydrogen peroxide by direct synthesis (i.e. hydrogen reacts with oxygen in the presence of a catalyst), which is on-site at a paper mill. The invention relates to a method for manufacturing hydrogen peroxide by direct synthesis from hydrogen originating from the recovery of the spent liquor during the manufacture of wood pulp or cellulose pulp. | 2011-05-05 |
| 20110104045 | Hydrogen Production With CO2 Capture - A method of hydrogen production including producing a syngas stream in an SMR and removing CO2 and H2 from the syngas stream in a CO2 removal unit, thereby producing a residue fuel stream is provided. The method also includes blending the residue fuel stream with a make-up fuel stream, thereby producing a blended fuel stream, and heating the blended fuel stream, thereby producing a heated blended fuel stream. The method also includes blending the heated blended fuel stream with a steam stream, thereby producing a raw reformer fuel stream, and introducing the raw reformer fuel stream into a LP reformer, thereby producing a reformer fuel stream. The method also includes combusting the reformer fuel stream to the SMR, thereby producing a flue gas that is essentially free of CO2. | 2011-05-05 |
| 20110104046 | METHOD FOR THE PRODUCTION OF HYDROGEN FROM THE DEHYDROCOUPLING OF AMINE BORANES - The present disclosure relates to processes and methods of generating hydrogen via the dehydrocoupling of amine boranes using ligand-stabilized homogenous metal catalysts. The amine-borane is shown by the formula (I), R | 2011-05-05 |
| 20110104047 | MODIFIED COBALT OXIDE BASED CATALYST FOR PRODUCING HYDROGEN, ITS PREPARATION METHOD AND USES THEREOF - Provided herein is a modified cobalt oxide based catalyst that includes cobalt oxide and lanthanum. The lanthanum is dispersed within the cobalt oxide, wherein the lanthanum is about 5-20% by weight of the modified cobalt oxide based catalyst. The method of producing the lanthanum modified cobalt oxide based catalyst and its use in producing hydrogen are also disclosed. | 2011-05-05 |
| 20110104048 | HYDROGEN-GENERATING COLLOIDAL SUSPENSION - Described is the use of a colloidal suspension that includes between 2 and 60% of alkaline metal particles that are suspended in a neutral hydrophobic diluent for producing gaseous hydrogen, as well as a process for producing hydrogen. Also described is a hydrogen-generating device and its use. | 2011-05-05 |
| 20110104049 | METHOD OF USING AN ANTI-CD137 ANTIBODY AS AN AGENT FOR RADIOIMMUNOTHERAPY OR RADIOIMMUNODETECTION - The current invention relates to the development and methods of use of a recombinant agonistic antibody anti-human CD137, and glycosylation variants thereof. These antibodies act as anti-cancer agents and/or immune modulators that are effective in shrinking solid tumors or other cancerous indications and preventing their recurrence. The types of cancer for which the contemplated antibody is effective in treating also include leukemia and lymphoma. In a preferred embodiment the recombinant antibodies of the current invention were produced in and purified from the milk of transgenic animals. In another preferred embodiment of the current invention the agonistic anti-CD137 antibodies of the invention can be conjugated to radionuclides for radioimmunodetection or radioimmunotherapeutic purposes, or conjugated to a toxin for enhanced therapeutic treatment of various cancers. | 2011-05-05 |
| 20110104050 | Compositions and Methods for Identifying and Targeting Cancer Cells of Alimentary Canal Origin - Screening and diagnostic reagents, kits and methods for primary and/or metastatic stomach or esophageal cancer are disclosed. Compositions for and methods of imaging and treating primary and/or metastatic stomach or esophageal cancer are disclosed. Vaccines compositions and methods of for treating and preventing primary and/or metastatic stomach or esophageal cancer are disclosed. | 2011-05-05 |
| 20110104051 | Chemically Modified Viral Capsids as Targeted Delivery Vectors for Diagnostic and Therapeutic Agents - The present invention provides a novel means of delivering imaging agents and/or therapeutic agents to specific cellular sites in an animal involving the use of a viral capsid that is chemically modified on it exterior and/or interior surfaces. | 2011-05-05 |
| 20110104052 | METHODS OF SYNTHESIS AND USE OF CHEMOSPHERES - The present invention provides, in general, compositions comprising a hydrogel and an agent, for example a therapeutic agent or an imaging agent, for locoregional delivery. In certain preferred embodiments of the invention, the hydrogel compositions are detectable by Magnetic Responance and CT Scan and are used for locoregional delivery of therapeutic agents, for example chemotherapeutic agents. The invention also features polymer matrix compositions comprising nanoparticles that can be loaded after polymerization with bioactive agents, for example a diagnostic agent or therapeutic agent. | 2011-05-05 |
| 20110104053 | HUMAN IgM ANTIBODIES, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF PARTICULARLY IN THE CENTRAL NERVOUS SYSTEM - Antibodies, and particularly human antibodies, are disclosed that demonstrate activity in the treatment of demyelinating diseases as well as other diseases of the central nervous system that are of viral, bacterial or idiopathic origin, including neural dysfunction caused by spinal cord injury. Neuromodulatory agents are set forth that include and comprise a material selected from the group consisting of an antibody capable of binding structures or cells in the central nervous system, a peptide analog, a hapten, active fragments thereof, agonists thereof, mimics thereof, monomers thereof and combinations thereof. The neuromodulatory agent has one or more of the following characteristics: it is capable of inducing remyelination; binding to neural tissue; promoting Ca | 2011-05-05 |
| 20110104054 | Small-Molecule HSP90 Inhibitors - Hsp90 inhibitors having are provided having the formula: | 2011-05-05 |
| 20110104055 | SUBSTITUTED N-ARYL BENZAMIDES AND RELATED COMPOUNDS FOR TREATMENT OF AMYLOID DISEASES AND SYNUCLEINOPATHIES - Compounds and their pharmaceutically acceptable salts, their synthesis and labeling, pharmaceutical compositions containing them, and their use in the treatment of amyloid diseases, including Aβ amyloidosis, such as observed in Alzheimer's disease, IAPP amyloidosis, such as observed in type 2 diabetes, and synucleinopathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment are provided. Also provided is the use of the disclosed compounds as imaging agents and methods for in vivo imaging and detection of amyloid and synuclein. | 2011-05-05 |
| 20110104056 | NOVEL MOLECULAR ASSEMBLY, MOLECULAR PROBE FOR MOLECULAR IMAGING AND MOLECULAR PROBE FOR DRUG DELIVERY SYSTEM USING THE SAME, AND MOLECULAR IMAGING SYSTEM AND DRUG DELIVERY SYSTEM - The present invention provides a molecular assembly which is less likely to accumulate in tissue other than cancer tissue, is highly safe for a living body, and can be prepared by a simple and safe method and whose particle size can be easily controlled. The present invention provides a molecular imaging system and a molecular probe useful for the system, and a drug delivery system and a molecular probe useful for the system. The present invention provides a method for preparing molecular assembly, by which the particle size of molecular assembly having a signal group or a drug can be arbitrarily controlled in order to allow the molecular assembly to effectively accumulate in cancer tissue by utilizing EPR effect. A molecular assembly comprising: an amphiphilic block polymer A comprising a hydrophilic block chain and a hydrophobic block chain having 10 or more lactic acid units; a hydrophobic polymer A2 having at least 10 or more lactic acid units; and/or a labeled polymer B comprising at least 10 or more lactic acid units and a labeling group. | 2011-05-05 |
| 20110104057 | Novel [F-18]-labelled L-glutamic acid and L-glutamine derivatives (II), their use and processes for their preparation - What is described are the compounds and the synthesis of [F-18]-labelled L-glutamic acid, [F-18]-labelled L-glutamate, their derivatives of the formula (I) and their use. | 2011-05-05 |
| 20110104058 | DIMERIC MOLECULAR COMPLEXES - Dimeric molecular complexes comprising an IgE CH4 dimerization domain useful for diagnostics and therapeutics. | 2011-05-05 |
| 20110104059 | Membrane Associated Tumor Endothelium Markers - To gain a better understanding of tumor angiogenesis endothelial cells (ECs) were isolated and gene expression patterns were evaluated. When transcripts from ECs derived from normal and malignant colorectal tissues were compared with transcripts from non-endothelial cells, over 170 genes predominantly expressed in the endothelium were identified. Comparison between normal- and tumor-derived endothelium revealed differentially expressed genes, including many that were specifically elevated in tumor-associated endothelium. Experiments with representative genes from this group demonstrated that most were similarly expressed in the endothelium of primary lung, breast, brain, and pancreatic cancers as well as in metastatic lesions of the liver. These results demonstrate that neoplastic and normal endothelium in humans are distinct at the molecular level. | 2011-05-05 |
| 20110104060 | TREATMENT OF HYPERTENSION BY RENAL VASCULAR DELIVERY OF GUANETHIDINE - Sympathetic nerves run through the adventitia surrounding renal arteries and are critical in the modulation of systemic hypertension. Hyperactivity of these nerves can cause renal hypertension, a disease prevalent in 30-40% of the adult population. Hypertension can be treated with neuromodulating agents (such as angiotensin converting enzyme inhibitors, angiotensin II inhibitors, or aldosterone receptor blockers), but requires adherence to strict regimens and often does not reach target blood pressure threshold to reduce risk of major cardiovascular events. A minimally invasive solution is presented here to reduce the activity of the sympathetic nerves surrounding the renal artery by locally delivering neurotoxic or sympathetic nerve-blocking agents into the adventitia. Extended elution of these agents may also be accomplished in order to tailor the therapy to the patient. | 2011-05-05 |
| 20110104061 | TREATMENT OF RENAL HYPERTENSION OR CAROTID SINUS SYNDROME WITH ADVENTITIAL PHARMACEUTICAL SYMPATHETIC DENERVATION OR NEUROMODULATION - Sympathetic nerves run through the adventitia surrounding renal arteries and are critical in the modulation of systemic hypertension. Hyperactivity of these nerves can cause renal hypertension, a disease prevalent in 30-40% of the adult population. Hypertension can be treated with neuromodulating agents (such as angiotensin converting enzyme inhibitors, angiotensin II inhibitors, or aldosterone receptor blockers), but requires adherence to strict medication regimens and often does not reach target blood pressure threshold to reduce risk of major cardiovascular events. A minimally invasive solution is presented here to reduce the activity of the sympathetic nerves surrounding the renal artery by locally delivering neurotoxic or nerve-blocking agents into the adventitia. Extended elution of these agents may also be accomplished in order to tailor the therapy to the patient. | 2011-05-05 |
| 20110104062 | Biomarkers for Head-And-Neck Cancers and Precancers - The invention provides markers and methods for detecting head-and-neck precancers, (including OPLs), cancers and related disease conditions in a subject. The invention also provides localization and imaging methods for head-and-neck precancers (including OPLs) and cancers, along with kits for carrying out methods of the invention. The invention further provides therapeutic applications for head-and-neck precancers (including OPLs) and cancers which employ head-and-neck precancer and cancer markers, polynucleotides encoding the markers, and binding agents for the markers. | 2011-05-05 |
| 20110104063 | FLEXIBLY LABELING PEPTIDES - A solid phase peptide synthesis method for synthesizing a peptidyl contrast agent is disclosed. In one example, the method includes synthesizing an amino-chelator loaded resin, coupling of the amino-chelator loaded resin to the C-terminus and/or backbone of a peptide, cleaving the amino-chelator-peptide from a resin, and chelating a lanthanide metal to the amino-chelator-peptide. | 2011-05-05 |
| 20110104064 | CYCLIZED NON-NATIVE SYNTHETIC PEPTIDE AND COMPLEX OF PEPTIDES COMPRISING SAID CYCLIZED PEPTIDE, INTENDED TO INDUCE AND TO CHARACTERIZE THE PREVENTION OR TREATMENT OF CONDITIONS IN MAMMALS - Non-native synthetic peptide cyclized by means of a disulphide bridge, characterized by the amino acid sequence (E34P) that follows (SEQ ID No. 1): E-D-E-H-K-G-K-Y-C-R-L-G-N-D-C-R-T-T-E-P-T-T-T-A-T-P-R-G-T-P-T-P-A-P and a complex of non-native synthetic peptides that is intended to induce and characterize the prevention and/or treatment of conditions in mammals, the protective immunity of which depends on the stimulation of Th1 type lymphocytes, and, in particular, on a state of delayed hyperstimulation, containing: —said peptide (E34P), —the following sequence (A16E) of 16 amino acids (SEQ ID No. 2) or derivatives (structural analogues) thereof: A-A-R-C-A-R-C-R-E-G-Y-S-L-T-D-E —the following sequence (A16G) of 16 amino acids (SEQ ID No. 3) or derivatives (structural analogues) thereof: A-A-S-S-T-P-S-P-G-S-G-C-E-V-D-G, —and an adjuvant which preferably induces a cell-mediated response. | 2011-05-05 |
| 20110104065 | GENETIC ALTERATION ASSOCIATED WITH PRE-MALIGNANT CANCER - Described herein are progenitor cancer cells and cell lines isolated from human breast ductal carcinoma in situ (DCIS) lesions and the uses of these cells or cell lines in drug design, drug screening, and monitoring in vivo therapy. The DCIS malignant precursor cells or cell lines are epithelial in origin, are positive for markers of autophagy, show at least one genetic difference from normal cells of said fragment, form 3-D tube-like structures or ball aggregates, or are inhibited in formation of 3-D structures and migration by treatment with chloroquine. In one embodiment, there is a loss of heterozygosity (LOH) that is narrowly confined to a region of chromosome 6p (6p21.1-6p12.3) that contains the SUPT3H gene. | 2011-05-05 |
| 20110104066 | PROPHYLACTIC/THERAPEUTIC AGENTS FOR LIFESTYLE-RELATED DISEASES - Disclosed is a method for the screening of a compound having an activity to selectively modulate an androgen receptor. The method comprises the steps of: contacting a substance to be tested with a prostate cancer cell and measuring the level of expression of mRNA for a prostate-specific antigen or the level of production of the prostate-specific antigen in the prostate cancer cell; and contacting the substance with an adipocyte and measuring the level of expression of mRNA for uncoupling protein-1 or the level of production of uncoupling protein-1 in the adipocyte. Also disclosed is a selective androgen receptor modulator comprising a compound represented by any one formula selected from the structural formulae (I) to (III) as an active ingredient. Further disclosed is a composition for preventing or treating lifestyle-related diseases, which comprises the selective androgen receptor modulator. | 2011-05-05 |
| 20110104067 | METHODS FOR IN VIVO EVALUATION OF PULMONARY PHYSIOLOGY AND/OR FUNCTION USING NMR SIGNALS OF POLARIZED 129XE - In certain embodiments, methods of the present invention obtain dynamic data sets of an NMR spectroscopy signal of polarized | 2011-05-05 |
| 20110104068 | Echogenic Coatings and Their Use in Medical Devices - The present teachings relate to echogenic coatings and medical devices coated with an echogenic coating. The echogenic coating can be prepared from a composition comprising a polymer and an effervescent agent in one or more anhydrous solvents. | 2011-05-05 |
| 20110104069 | MULTI-FUNCTIONAL BIODEGRADABLE PARTICLES FOR SELECTABLE TARGETING, IMAGING, AND THERAPEUTIC DELIVERY AND USE THEREOF FOR TREATING OCULAR DISORDERS - In various embodiments, provided are multi-functional biodegradable particles for selectable targeting, imaging, and delivery of therapeutic agents. Also provided are methods of using the provided particles for treatment of ocular disorders, such as for the treatment of age-related macular degeneration. The provided particles and methods provide a clinician with options for control over, and monitoring of, the delivery of therapeutic agents. | 2011-05-05 |
| 20110104070 | SITE SPECIFIC FLUORESCENCE AND CONTRAST MARKER FOR SAME - A contrast marker for indicating a presence of a target cell in an environment comprises a fluorophore, an NMP, and a short spacer and a long spacer linking the fluorophore to the NMP. The short spacer holds the fluorophore at a quenching distance from the NMP and the long spacer holds the fluorophore at a fluorescence enhancing distance from the NMP. The short spacer is configured to be cleaved by a molecule characterizing the target cells. | 2011-05-05 |
| 20110104071 | METHODS AND SYSTEMS FOR SPATIALLY IDENTIFYING ABNORMAL CELLS - The present invention provides compositions and methods for imaging tumor resections. | 2011-05-05 |
| 20110104072 | TREATING WATER INSOLUBLE NANOPARTICLES WITH HYDROPHILIC ALPHA-HYDROXYPHOSPHONIC ACID CONJUGATES, THE SO MODIFIED NANOPARTICLES AND THEIR USE AS CONTRAST AGENTS - The present application discloses treating water insoluble nanoparticles, particularly nanoparticles of metals and metal compounds which find utility in diagnostic imaging such as MR and X-ray imaging, with an alpha-hydroxyphosphonic acid conjugate with a hydrophilic moiety to render the nanoparticles sufficiently hydrophilic to find utility in diagnostic imaging. Among the modified hydrophilic nanoparticles disclosed are those in which the hydrophilic moieties of the modifying conjugate are ethylene oxide based polymers and copolymers and zwitterions and the nanoparticles are composed of transition metal oxides such as superparamagnetic iron oxide and tantalum oxide. Disclosed are nanoparticles which are sufficiently hydrophilic to form stable aqueous colloidal suspensions. Also disclosed is diagnostic imaging such as MR and X-ray using the modified hydrophilic nanoparticles as contrast agents. | 2011-05-05 |
| 20110104073 | Iron/Iron Oxide Nanoparticle and Use Thereof - The present invention is a nanoparticle composition composed of an iron core with an iron oxide shell which is optionally coated with a micro-emulsion. The disclosed nanoparticle compositions are disclosed for use in hyperthermia treatment and imaging of cancer. | 2011-05-05 |
| 20110104074 | METHODS FOR TARGETED CANCER TREATMENT AND DETECTION - A method for treating a cancer is provided that comprises identifying a subject in need of treatment for a cancer and administering to the subject a composition that is comprised of a plurality of a ligand for a luteinizing hormone-releasing hormone receptor and a plurality of a chemotherapeutic agent, where each ligand and each chemotherapeutic agent are conjugated to a nanoparticle. Further provided are methods for detecting a cancer in a subject that comprise administering to a subject an imaging agent comprised of a plurality of a ligand for a luteinizing hormone-releasing hormone receptor conjugated to a nanoparticle. | 2011-05-05 |
| 20110104075 | 129Xe BIOSENSORS AND THEIR USE - This invention relates to enzyme-sensitive biosensors and methods and kits using the same. Specifically, the invention relates to methods, systems and kits for the detection of enzymes using the chemical shift observed in an isotope complexed to the biosensor resulting from a change in the biosensor as the result of the enzyme's activity. | 2011-05-05 |
| 20110104076 | Compositions, Methods For Preparing Amino Acids And Nuclear Magnetic Resonance Spectroscopy - The present invention relates to amino acids, complexes, and compounds comprising deuterium and tritium isotopes preferably alpha deuterated amino acids, polypeptides, antibodies, derivatives and saccharide-amino acid complexes and conjugates. In some embodiments, the invention relates to methods of using compounds comprising deuterium for imaging biochemical concentrations and distributions in mammalian tissues using nuclear magnetic resonance spectroscopy. In some embodiments, the invention relates to the used of said amino acids derivatives and complexes in boron neutron capture therapy. In some embodiments, the present invention relates to the preparation of amino acids, polypeptides, antibodies, derivatives and saccharide complexes/conjugates comprising heavy hydrogen isotopes. In some embodiments, the invention relates to racemizing amino acids starting from compositions of any optical purity. In further embodiments, the invention relates to the preparation of amino acids and their N-acyl counterparts with deuterium incorporated at the alpha carbon. | 2011-05-05 |
