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18th week of 2012 patent applcation highlights part 63
Patent application numberTitlePublished
20120108820IONIC LIQUIDS BASED ON IMIDAZOLIUM SALTS INCORPORATING A NITRILE FUNCTIONALITY - Novel chemical compounds of the general formula2012-05-03
20120108821PROCESS FOR PRODUCING CRYSTALS OF POLYMORPHIC 2-(3-CYANO-4-ISOBUTYLOXYPHENYL)-4-METHYL-5-THIAZOLECABOXYLIC ACID BY POOR-SOLVENT ADDITION METHOD - Disclosed is a process for producing A-form crystals of 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid, comprising: a step of dissolving by heating 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid in one or a plurality of solvents as a good solvent, selected from the group consisting of 1-propanol, 2-propanol, ethanol, and acetone; a step of cooling the solution; and a step of adding to the solution a hydrocarbon solvent as a poor solvent.2012-05-03
20120108822Process For The Preparation Of Chalcogene Compounds - The present invention is a novel process for the preparation of chalcogenone compounds by conversion of ionic liquids and salts comprising nitrogen-containing heterocyclic cations and basic anions to the corresponding nitrogen-containing heterocyclic chalcogenones by reaction with elemental chalcogens.2012-05-03
20120108823ANTI-FRANCISELLA AGENTS - A series of celecoxib derivatives defined by Formula I:2012-05-03
20120108824CRYSTALLISATION PROCESS FOR 1-(BETA-D-GLUCOPYRANOSYL)-4-METHYL-3-[5-(4-FLUOROPHENYL)-2-THIENYLMETHYL] BENZENE - The present invention relates to a crystallisation procedure to obtain 1-(β-D- glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl] benzene hemihydrate crystals having a narrow particle size distribution and improved flowability, bulk and tap density properties.2012-05-03
20120108825AMORPHOUS SILIBININ FOR THE TREATMENT OF VIRAL HEPATITIS - The invention relates to a method for the preparation of amorphous silibinin (or its synonyms: silybin or silibin) derived from a milk thistle fruit extract having an increased release rate and improved absorbability or bioavailability, and to the use of amorphous silibinin for the treatment or prevention of liver diseases, preferably for the treatment of viral hepatitis, e.g. hepatitis B or C, in particular in a patient who will undergo or has undergone liver transplantation. Preferably, the amorphous silibinin is adapted for oral administration.2012-05-03
20120108826PROCESS FOR PREPARING NEBIVOLOL - The present invention relates to a process for preparing Nebivolol and, more in particular, to a fractional distillation method of a mixture of stereoisomers of formula2012-05-03
20120108827PROCESS FOR CONVERTING POLYSACCHARIDES IN AN INORGANIC MOLTEN SALT HYDRATE - A process is disclosed for converting a polysaccharide-containing biomass material to platform chemicals.2012-05-03
20120108828SYNTHESIS OF DRONEDARONE AND SALTS THEREOF - The present invention relates to a process for preparation of Dronedarone or pharmaceutically acceptable salts thereof. More particularly, the present invention provides a process for preparation of Dronedarone hydrochloride, without the isolation of Dronedarone base.2012-05-03
20120108829PROCESS FOR THE PRODUCTION OF FURFURAL FROM PENTOSES - The invention is directed to a process for the production of furfural from pentoses and/or water soluble pentosans, said process comprising converting the said pentoses and/or water soluble pentosans in aqueous solution in a first step to furfural and in a second step feeding the aqueous solution containing furfural obtained in the first step to the top of a distillation column to produce an aqueous, liquid downflow, which column is heated at the bottom to produce an upflow water vapour flow, recovering a gaseous water and furfural containing product stream from the top of the said column, compressing the said vapour flow and condensing it on the hot side of a reboiler at the bottom of the said column.2012-05-03
20120108830METHOD FOR MANUFACTURING AN EPOXY COMPOUND AND METHOD FOR EPOXIDIZING A CARBON-CARBON DOUBLE BOND - The present invention provides a method for producing an epoxy compound, comprising oxidizing a carbon-carbon double bond of an organic compound by hydrogen peroxide in the presence of a neutral inorganic salt and a mixed catalyst of a tungsten compound (a), at least one phosphorus compound selected from the group consisting of phosphoric acids, phosphonic acids, and salts thereof (b) and a surfactant (c), and an epoxidizing method comprising oxidizing a carbon-carbon double bond by hydrogen peroxide in the presence of the catalyst and the neutral inorganic salt.2012-05-03
20120108831SUPPORTED NOBLE METAL COMPRISING CATALYST FOR OXIDATIVE DEHYDROGENATION OR EPOXIDATION - Supported noble metal-comprising catalysts which can be obtained by 2012-05-03
20120108832 ALUMINA SUPPORT, A PROCESS FOR PREPARING THE SUPPORT, A SILVER CATALYST PREPARED FROM THE SUPPORT, AND USE THEREOF - An alumina support comprises alpha-alumina as the main crystal phase of its backbone, and having a specific surface area of no higher than 3.0 m2012-05-03
20120108833PROCESS FOR THE PREPARATION OF PHYTOSTERYL FERULATE - A method is provided for controlling the operating temperature of a catalytic reactor using a closed-loop system that provides for varying the reactor input and other operating parameters in order to maintain the operating temperature of the reactor at or near the initial setpoint temperature for operation of the reactor. In one example, maximum and minimum operating temperatures with a catalytic partial oxidation reactor are controlled, as well as maintaining control over the corresponding minimum required ratio of oxygen atoms to carbon atoms, such that the operating temperature within the reactor is maintained below the material limits but above threshold temperatures for coking.2012-05-03
20120108834BIOLUBRICANT ESTERS FROM THE ALCOHOLS OF UNSATURATED FATTY ACIDS - The present invention is generally directed to triester-based lubricant compositions. The present invention is also directed to methods of making these and other similar lubricant compositions. In some embodiments, the methods for making such triester-based lubricants utilize a biomass precursor comprising mono-unsaturated fatty acids, wherein such mono-unsaturated fatty acids are reduced to mono-unsaturated fatty alcohols en route to the synthesis of triester species for use as/in the triester-based lubricant compositions. Subsequent steps in such synthesis may employ carboxylic acids and/or acyl halides/anhydrides derived from biomass and/or Fischer-Tropsch synthesis.2012-05-03
20120108835PROCESS FOR THE PREPARATION OF FE(III) CHELATES OF N,N'-DI(2-HYDROXYBENZYL)-ETHYLENEDIAMINE-N,N'-DIACETIC ACID AND ITS DERIVATIVES - The invention relates to the process for the preparation of iron(III) chelates of N,N-di(2-hydroxybenzyl)ethylenediamine-N,N′-diacetic acid and its derivatives of the formula (I) wherein both R substituents have the same meaning and represent H, C2012-05-03
20120108836METHOD FOR PREPARING FLUOROALKANESULPHINIC ACID ESTERS - A method for preparing fluoroalkanesulphinic acid esters is described. The preparation of esters of trifluoromethanesulphinic acid, commonly referred to as “triflinic acid,” is also described. A method for preparing a fluoroalkanesulphinic acid ester is also described wherein the method includes reacting a fluoroalkanesulphinic acid with an organic carbonate leading to the formation of a fluoroalkanesulphinic acid ester and carbon dioxide, which is removed during the reaction.2012-05-03
20120108837RADICAL POLYMERIZABLE MACROCYCLIC RESIN COMPOSITIONS WITH LOW POLYMERIZATION STRESS - A composition of macrocyclic oligomer with at least one (meth)acrylate polymerizable group. A method includes preparing an activated precursor of an oligomer at pseudo high-dilution conditions. A method also includes preparing an activated precursor of an oligomer by reacting the precursor with an activated coupling agent, wherein the precursor is condensable and polymerizable.2012-05-03
20120108838SYNTHESIS OF AN ENERGETIC NITRATE ESTER - Preparation of an energetic nitrate ester compound and related intermediates is provided.2012-05-03
20120108839PROCESS FOR PREPARING PROSTAGLANDIN DERIVATIVES - The present invention relates to a process for preparing a prostaglandin derivative and an intermediate therefor. In accordance with the present invention, the prostaglandin F (PGF) derivative can be efficiently prepared with high purity by removing the protecting group of a protected prostaglandin E (PGE) derivative obtained from conjugate addition and then stereoselectively reducing the ketone group on the cyclopentanone ring of the PGE derivative.2012-05-03
20120108840MOLDING METHOD OF POLYMER STABILIZER - A polymer stabilizer can be molded easily by compression-molding a compound represented by formula (1):2012-05-03
20120108841SIMULATED MOVING BED MEMBRANE REACTOR, NEW HYBRID SEPARATION PROCESS AND USES THEREOF - The presently disclosed subject matter is a new technology, related to a simulated moving bed membrane reactor. This novel technology includes a reactor with two different separation techniques: i) chromatography (simulated moving bed—SMB); ii) selective permeable membrane (namely, pervaporation and permeation, among others) into a single device, allowing a significant increase in the unity productivity and considerable reduction of solvent consumption and consequently lowers downstream costs associated to the following separation units, for the same product purity and reactants conversion criteria. It has its main applications in the chemical industry, particularly, in the continuous production of oxygenated compounds as esters, acetals, ethers, carbonates, among others.2012-05-03
20120108842Methods for Producing a Vinyl Acetate Composition Having a Low Impurity Content - In one embodiment, the invention is to a method for producing a vinyl acetate composition. The method comprises the step of contacting acetic acid, oxygen, and ethylene under conditions effective to form a crude vinyl acetate composition comprising vinyl acetate, acetic acid, residual oxygen, and water. The method further comprises the step of contacting the crude vinyl acetate composition or a derivative thereof with at least one scavenger to form a treated crude vinyl acetate composition.2012-05-03
20120108843PROCESS FOR THE PREPARATION OF LIGHT-COLORED IOCYANATES OF A DIPHENYLMETHANEDIISOCYANATE SERIES - The present invention accordingly provides a process for preparing light-coloured polyphenylene-polymethylene polyisocyanates comprising the steps (a) providing an amount of chlorine, (b) separating the chlorine provided in the step (a) to obtain a first chlorine fraction having a content of free and bound bromine and iodine of <50 ppm and a second chlorine fraction having an increased content of free and bound bromine and iodine that depends on the original amount of bromine and iodine in the chlorine provided in step (a) and the separation split, (c) reacting carbon monoxide with at least a portion of the first chlorine fraction to form a first phosgene fraction, (d) reacting carbon monoxide with at least a part of the second chlorine fraction to form a second phosgene fraction, (e) reacting at least a portion of a first phosgene fraction with at least one amine of the diphenylmethane diamine series (MDA) to form the corresponding polyphenylene-polymethylene polyisocyanate (PMDI), and (f) reacting at least a portion of the second phosgene fraction with at least one primary amine with the exception of mono- and polyphenylene-polymethylene polyamines to form an at least one isocyanate-containing reaction solution.2012-05-03
20120108844METHOD OF MEASURING ENTRY OF WATER INTO PHOSGENE-CONDUCTING PLANTS - The invention relates to a method of measuring entry of water and resulting corrosion in plants for producing isocyanates by reacting phosgene with one or more primary amines in a solvent. The invention further relates to an apparatus for producing such isocyanates, in the work-up section of which probes for monitoring corrosion are arranged in defined places.2012-05-03
20120108845PROCESS FOR THE PREPARATION OF ISOCYANATES IN THE GAS PHASE - Isocyanates are produced by reacting a primary amine with phosgene in the gas phase. In this process, the amine is vaporized and then superheated prior to introduction into the reactor. The amine is superheated to a temperature at least 10° C. above dew point before entry into the reactor. A pressure difference between the vaporizer and entry into the reactor of from 1 to 500 mbar is maintained.2012-05-03
20120108846OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY, AND METHOD FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF BY USING THE SAME - The present invention discloses an optically active quarternary ammonium salt having axial asymmetry and a method for producing an α-amino acid and a derivative thereof using the same. The optically active quarternary ammonium salt having axial asymmetry of the present invention is a chiral phase-transfer catalyst that has a simple structure and that can be produced in a smaller number of process steps. The compound of the present invention is very useful as a phase-transfer catalyst in the synthesis of an α-alkyl-α-amino acid and a derivative thereof as well as an α,α-dialkyl-α-amino acid and a derivative thereof. Therefore, the compound of the present invention can be used in the development of novel foods and pharmaceuticals.2012-05-03
20120108847DEVICE AND PROCESS FOR CRYSTALLIZING (METH) ACRYLIC ACID - The objective of the present invention is to provide a crystallization device and a crystallization process for obtaining (meth)acrylic acid with higher purity without causing leakage of a crude solution by preventing complete clogging in a crystallization tube from occurring. The device for crystallizing (meth)acrylic acid according to the present invention is characterized in comprising a crude (meth)acrylic acid solution supply part, a crystallization tube, a heat medium supply tube, a heat medium discharge tube, a storage part of a crude (meth)acrylic acid solution passed through the crystallization tube, a tube for circulating and supplying the crude (meth)acrylic acid solution to the supply part from the storage part, and a pump for circulating and supplying the crude (meth)acrylic acid solution to the supply part from the storage part; and further comprising a pressure meter in the circulate-supply tube; wherein the device is used for carrying out dynamic crystallization in a batch manner by circulating the crude (meth)acrylic acid solution to flow the crude solution downward along the inner wall of the crystallization tube in a coating film-like state.2012-05-03
20120108848PROCESS FOR RESOLUTION OF 1-(3-HYDROXYPHENYL)-2-METHYLAMINO ETHANOL - Resolution of the title compound to its active isomer (R)-1-(3-hydroxyphenyl)-2-methylamino ethanol with (R)-naproxen as a resolving agent.2012-05-03
20120108849POLYFLUOROALKYLPHOSPHONIC ACID ESTER AND PROCESS FOR PRODUCING THE SAME - A polyfluoroalkylphosphonic acid ester represented by the general formula: C2012-05-03
20120108850POLYACENE COMPOUND AND ORGANIC SEMICONDUCTOR THIN FILM - The present invention provides an organic semiconductor material which exhibits a high mobility, and excellent solubility in solvents and oxidation resistance. The present invention also provides an organic semiconductor thin film exhibiting a high mobility, and an organic semiconductor device exhibiting excellent electronic characteristics. A transistor structure is formed by coating the silicon substrate with a thin film of pentacene compound substituted halogens at 6 and 13 positions and aliphatic hydrocarbons at 2, 3, 9 and 10 positions, wherein the substrate is patterned beforehand with gold to have a source and drain electrodes.2012-05-03
20120108851METHOD FOR PRODUCING NORBORNENE DERIVATIVE - A method for producing a norbornene derivative includes forming a Mannich base represented by any of general formulae (5) to (7) by reacting a carbonyl compound represented by any of general formulae (1) to (3) and an amine compound represented by general formula (4) with each other in an acidic solvent, to thereby obtain a reaction liquid comprising the Mannich base in the acidic solvent, wherein the acidic solvent comprises a formaldehyde derivative and 0.01 mol/L or more of an acid represented by formula HX; reacting the Mannich base and a diene compound represented by general formula (8) with each other by adding an organic solvent, a base in an amount of 1.0 to 20.0 equivalents to the acid, and the diene compound to the reaction liquid, and then heating the reaction liquid, to thereby form the norbornene derivative represented by any of general formulae (9) to (11).2012-05-03
20120108852METHOD FOR REPROCESSING A LIQUID HYDROFORMYLATION PRODUCT - The invention relates to a method for reprocessing a liquid product of a hydroformylation reaction, wherein the liquid phase produced in a release stage is supplied to a separating device from which a liquid flow containing rhodium is guided away via a filter, where solids thereby separated are taken out of the process and the filtrate obtained is guided back into the hydroformylation reaction.2012-05-03
20120108853METHOD FOR PRODUCING TRISPHENOLS AND MONOESTER-SUBSTITUTED PRODUCTS THEREOF, AND 4-ACYLARALKYLPHENOL DERIVATIVES - Trisphenols of general formula (1), which are useful as starting materials for polymer, are industrially easily produced by a method using as a starting material 4-aralkylphenol derivatives expressed by general formula (2):2012-05-03
20120108854GREEN AND ATOM-ECONOMICAL PROCESSES FOR PRODUCING PHENOLIC ANTIOXIDANTS - Processes for producing 1,3,5-trimethyl-2,4,6-tris(3,5-dialkyl-4-hydroxybenzyl)benzene are provided, in particular such processes that utilize 2,6-di-tert-butylphenol, paraformaldehyde, a secondary amine, mesitylene, and acetic acid.2012-05-03
20120108855INCREASED EXPRESSION OF TRANSHYDROGENASE GENES AND THEIR USE IN ETHANOL PRODUCTION - The invention provides isolated or recombinant ethanologenic bacteria that have increased expression of transhydrogenase genes and methods of preparation. The invention also provides methods of producing ethanol using the bacterium and corresponding kits.2012-05-03
20120108856PROCESS FOR PREPARING DICHLOROHYDRIN - The invention relates to a process wherein a stream comprising dichlorohydrin, water, and HCI is separated into a stream which is rich in dichlorohydrin and low in HCI and an aqueous HCI stream which is low in dichlorohydrin. The process involves the distillation of the mixture comprising dichlorohydrin, water, and HCI with an amount of water being added before and/or during the distillation such that the water concentration during the distillation is on the line D-E, or to the right thereof, in the phase diagram of FIG. 2012-05-03
20120108857CRYSTALLIZATION UNIT FOR ACRYLIC ACID AND METHOD FOR CRYSTALLIZATION OF ACRYLIC ACID USING THE SAME2012-05-03
20120108858METHOD AND DEVICE FOR MANUFACTURING OF RADIOPHARMACEUTICALS - The invention relates to a device for processing radioisotopes and production of radiopharmaceuticals, for example, 18F-2 Deoxy-2-Fluoro-D-Glucose (FDG), for Positron Emission Tomography (PET). Use of a tilting and rotating reactor with optimized geometry allows for decreased processing time and increased efficiency. Reagent vials are separated from the reactor module and placed in a separate enclosure allowing safe reloading of the system and production of multiple batches with minimal operator exposure to radiation. Reagent vials enclosure is protected from the environment and filled with purified air to reduce risk of contamination. Product and reagents pathways are sealed from the environment and are sterilized.2012-05-03
20120108859USE OF COPPER-NICKEL CATALYSTS FOR DEHLOGENATION OF CHLOROFLUOROCOMPOUNDS - The disclosure describes a process for dehalogenation of chlorofluorocompounds. The process comprises contacting a saturated chlorofluorocompound with hydrogen in the presence of a catalyst at a temperature sufficient to remove chlorine and/or fluorine substituents to produce a fluorine containing terminal olefin.2012-05-03
20120108860PROCESS FOR PRODUCING HIGH QUALITY PYROLYSIS OIL FROM BIOMASS - This invention relates to a process to utilize a torrefaction pretreatment step for biomass pyrolysis process. This pretreatment improves the quality of the pyrolysis oil by reducing acidity. The inventive process shows that as a pretreatment to pyrolysis, resulting pyrolysis oil obtained from torrefied biomass has approximately 25% lower acetic acid than that from untorrefied biomass pyrolysis oil.2012-05-03
20120108861PROCESS FOR CONVERSION OF BIOMASS TO FUEL - The present invention is directed to processes for the direct conversion of lipidic biomass fuelstock to combustible fuels. In particular, the invention provides a process for the direct conversion of animal fats to transportations fuels suitable as replacement for petroleum-derived transportation fuels. In one embodiment, the method comprises the steps of hydrolyzing a lipidic biomass to form free fatty acids, catalytically deoxygenating the free fatty acids to form n-alkanes, and reforming at least a portion of the n-alkanes into a mixture of compounds in the correct chain length, conformations, and ratio to be useful transportation fuels. Particularly, the product prepared according to the invention comprises mixtures of hydrocarbon compounds selected from the group consisting of n-alkanes, isoalkanes, aromatics, cycloalkanes, and combinations thereof.2012-05-03
20120108862RECOVERY AND USE OF CONJUNCT POLYMERS FROM IONIC LIQUID CATALYSTS - A process comprising regenerating a used ionic liquid catalyst, recovering conjunct polymer from the regenerated catalyst and using at least a portion of the conjunct polymer is disclosed.2012-05-03
20120108863Depolymerizatin of Plastic Materials - A styrene monomer reclamation process and system is disclosed. The styrene monomer reclamation process includes providing a waste plastic. The waste plastic includes styrenic polymers. The waste plastic is formed into polymer particles. At least a portion of the polymer particles are dissolved in a solvent to form a polymer stream. The dissolved polymer particles are depolymerized to form a styrene monomer stream.2012-05-03
20120108864INTEGRATED PROPYLENE PRODUCTION - A process for the production of propylene, the process including: fractionating a hydrocarbon stream comprising n-butenes, isobutylene, and paraffins into at least two fractions including a light C2012-05-03
20120108865WATER GAS SHIFT FOR ACETYLENE CONVERTER FEED CO CONTROL - A process and apparatus are presented for the removal of carbon monoxide from ethylene streams. The removal of carbon monoxide before selective hydrogenation protects the catalyst in the selective hydrogenation reactor. Carbon monoxide levels are controlled with the water gas shift process to convert the carbon monoxide to carbon dioxide, with the carbon dioxide removed in an acid gas removal process.2012-05-03
20120108866 PROCESS FOR THE SELECTIVE HYDROGENATION AND HYDRODESULFERIZATION OF A PYROLYSIS GASOLINE FEEDSTOCK - Disclosed is a process for the selective hydrogenation of diolefins and sulfur compounds that are contained in a pyrolysis gasoline feedstream. The process includes utilizing a single hydrotreating reaction stage by introducing the pyrolysis gasoline feedstock that includes a diolefin concentration and an organic sulfur concentration into a reactor that is loaded with a high activity hydrotreating catalyst and which is operated under selective hydrogenation conditions. A reactor effluent having a reduced diolefin concentration and a reduced organic sulfur concentration is yielded from the reactor and is separated into a portion that is recycled as a reactor feed. The remaining portion of the reactor effluent is passed downstream for further processing or handling.2012-05-03
20120108867Process for the Production of Purified Xylene Isomers - The invention is directed to a process to produce paraxylene and orthoxylene, including reducing the amount of isomerate recycle from vapor phase xylenes isomerization by providing a parallel configuration of vapor phase and liquid phase isomerization units.2012-05-03
20120108868Process for the Production of Paraxylene - A process for the purification of aromatic feedstream to produce paraxylene is disclosed, including the separation of a C8+ aromatic feedstream into a steam comprising C8 aromatic species and a stream comprising C9+ aromatic species. After separation of PX from the C8 aromatic stream, a PX-depleted stream is separated and processed in a liquid phase isomerization unit and a vapor phase isomerization unit in parallel.2012-05-03
20120108869FUEL AND BASE OIL BLENDSTOCKS FROM A SINGLE FEEDSTOCK - A method comprising the steps of providing a quantity of biologically-derived oil comprising triglycerides; processing the biologically derived oil so as to transesterify at least some of the triglycerides contained therein to yield a quantity of saturated monoesters and unsaturated monoesters; oligomerizing at least some of the unsaturated monoesters to yield a quantity of fatty acid ester oligomers; separating at least some of the saturated monoesters from the fatty acid ester oligomers; and hydrotreating at least some of the fatty acid ester oligomers to yield a quantity of alkanes.2012-05-03
20120108870FUEL AND BASE OIL BLENDSTOCKS FROM A SINGLE FEEDSTOCK - A method comprising the steps of providing a fatty acyl mixture comprising: (i) a C2012-05-03
20120108871FUEL AND BASE OIL BLENDSTOCKS FROM A SINGLE FEEDSTOCK - A method comprising providing a fatty acyl mixture comprising: (i) a C2012-05-03
20120108872HEAVY ALKYLBENZENE TRANSALKYLATION OPERATING COST REDUCTION - A process for increasing the production of monoalkylbenzenes is presented. The process includes utilizing a transalkylation process to convert dialkylbenzenes to monoalkylbenzenes. The transalkylation process recycles a portion of the effluent stream from the transalkylation reactor back to the feed of the transalkylation reactor. The recycled dialkylbenzenes and a portion of the recycled benzene are converted to monoalkylbenzenes.2012-05-03
20120108873Catalysts Containing Nano-Materials and Methods of Making and Using Same - A method of making a catalyst containing nanosize zeolite particles supported on a support material is disclosed. A process for making styrene or ethylbenzene by reacting toluene with a C2012-05-03
20120108874PROCESS FOR PREPARING A PHENYLCYCLOHEXANE - The present invention relates to an improved process for preparing a substituted or unsubstituted phenylcyclohexane by catalytic hydrogenation of a substituted or unsubstituted biphenyl.2012-05-03
20120108875ZEOLITE CATALYST WITH DEPOSITED GERMANIUM, ALUMINUM AND PLATINUM FOR AROMATIZATION OF ALKANES, PROCESS OF MAKING AND PROCESS OF USING THEREOF - The present invention is for a catalyst, a process for making the catalyst and a process for using the catalyst in aromatization of alkanes having three to five carbon atoms per molecule, such as propane, to aromatics, such as benzene, toluene and xylene. The catalyst is an aluminum-silicon zeolite having a silicon to aluminum atomic ratio (Si:Al) greater than 15:1, such as MFI or ZSM-5, on which germanium, aluminum and a noble metal, such as platinum, have been deposited. The catalyst may be bound with magnesia, alumina, titania, zirconia, thoria, silica, boria or mixtures thereof. The aluminum and germanium may be deposited simultaneously on the zeolite.2012-05-03
20120108876PROCESS AND REACTOR SYSTEM FOR THE PREPARATION OF AN OLEFINIC PRODUCT - A process and a reactor system for the preparation of an olefinic product by reacting an oxygenate feedstock in the presence of an oxygenate conversion catalyst within a reactor system under oxygenate-to-olefin conversion conditions, to obtain the olefinic product, wherein the reactor system has a contact surface coming in contact with oxygenates and wherein at least part of the contact surface is an material of the formula MX wherein: M is a metal and X is C, or M is a metal or Si and X is N.2012-05-03
20120108877PROPANE DEHYDROGENATION PROCESS UTILIZING FLUIDIZED CATALYST SYSTEM - A process for the production of propylene from a propane rich hydrocarbon source is presented. The process converts a propane rich stream and uses less equipment and energy for the separation and production of propylene. The process uses a non-noble metal catalyst and utilizes a continuous reactor-regeneration system to keep the process on line for longer periods between maintenance.2012-05-03
20120108878Novel Chemistries, Solutions, and Dispersal Systems for Decontamination of Chemical and Biological Systems - The present invention relates generally to chemical and biological decontamination solutions and methods of using them. The invention is useful for decontaminating a wide range of compounds and organisms. In particular, the systems, methods, solutions, and formulations of the invention can be used to remove and/or neutralize organophosphates and other toxic chemicals, bacteria, bacterial spores, fungi, molds and viruses.2012-05-03
20120108879MICROWAVE DISPOSAL SYSTEM FOR HAZARDOUS SUBSTANCES - A system and method for destruction of energetic compounds, medical wastes and unwanted pharmaceuticals using microwave energy. Waste materials are first mixed into a dilute water solution, slurry or emulsion. The dilute waste flows to a first microwave reactor containing silicon carbide. The silicon carbide absorbs the microwave energy, heats and vaporizes the liquid. The vapor flows to a second microwave reactor containing silicon carbide and an oxidation catalyst. Air is added and the waste portion of the vapor is oxidized to carbon dioxide. Water is recovered in a condenser and recycled. Carbon dioxide and remaining air is vented. Solid organic wastes such as contaminated disposable gloves and towels are gasified in a first microwave reactor with air and oxidized in the second microwave reactor.2012-05-03
20120108880CHROMOSOME 3p21.3 GENES ARE TUMOR SUPPRESSORS - Tumor suppressor genes play a major role in the pathogenesis of human lung cancer and other cancers. Cytogenetic and allelotyping studies of fresh tumor and tumor-derived cell lines showed that cytogenetic changes and allele loss on the short arm of chromosome 3 (3p) are most frequently involved in about 90% of small cell lung cancers and greater than 50% of non-small cell lung cancers. A group of recessive oncogenes, Fus1, 101F6, Gene 21 (NPRL2), Gene 26 (CACNA2D2), Luca 1 (HYAL1), Luca 2 (HYAL2), PL6, 123F2 (RaSSFI), SEM A3 and Beta* (BLU), as defined by homozygous deletions in lung cancers, have been located and isolated at 3p21.3.2012-05-03
20120108881EXPANDABLE BRACHYTHERAPY APPARATUS AND METHODS FOR USING THEM - Brachytherapy treatment apparatus are provided that include an elongate core member, a plurality of expandable catheters or other elongate members and a balloon or other expandable member on a distal portion adjacent the core member. Each catheter includes a distal end coupled to the core member distal end, a proximal end movable relative to the core member, and a lumen extending between the proximal and distal ends for receiving a source of radiation therealong. The balloon is expandable independently of the catheters such that the balloon may be expanded after expanding the catheters, e.g., to facilitate imaging and/or dose planning. Optionally, a working channel may be provided for receiving an aspiration catheter or other instrument or at least one of the catheters may include an aspiration lumen and one or more ports, e.g., for aspirating material from a region surrounding the distal portion.2012-05-03
20120108882Brachytherapy Devices and Related Methods Providing Bioaborbability and/or Asymmetric Irradiation - A brachytherapy device includes a sealed housing having a radioactive material therein, and at least one shielding member extending away from the housing and configured to provide radiation shielding on at least one side of the housing.2012-05-03
20120108883SYSTEMS AND METHODS FOR INDUCING ELECTRIC FIELD PULSES IN A BODY ORGAN - Systems and methods for providing controllable pulse parameter magnetic stimulation are described. One aspect is directed to a magnetic stimulation system for inducing approximately rectangular electric field pulses in a body organ, comprising an electrical energy storage device, a stimulating coil, and a switching means for electrically coupling said electrical energy storage device to said stimulating coil to produce current pulses in said stimulating coil which generates, in response to the current pulses, magnetic field pulses that can induce approximately rectangular electric field pulses in the body organ.2012-05-03
20120108884MULTI-POLAR MAGNETIC DEVICES FOR TREATING PATIENTS AND METHODS THEREFOR - A system for treating patients includes a first magnetic device including a set of four magnetic discs arranged in a square array, the four magnetic discs including two having negative magnetic poles lying in a first plane and two having positive magnetic poles lying in the first plane, wherein the two magnetic discs having negative magnetic poles extend along a first diagonal line and the two magnetic discs having positive magnetic poles extend along a second diagonal line that crosses the first diagonal line, and a housing containing the four magnetic discs for maintaining the magnetic discs in the square array arrangement, the housing including an alignment marker for aligning the first magnetic device on a patient.2012-05-03
20120108885Skin interface for ventricular assist device - Devices and methods are disclosed for implanting, positioning, removing, replacing and operating intra-aortic balloon pumps.2012-05-03
20120108886INTERNAL DRIVE LINE FOR VENTRICULAR ASSIST DEVICE - Devices and methods are disclosed for implanting, positioning, removing, replacing and operating intra-aortic balloon pumps.2012-05-03
20120108887HEARING PROSTHESIS HAVING AN IMPLANTABLE ACTUATOR SYSTEM - An implantable actuator system is disclosed. The system comprises a hermetically sealed housing; an actuator positioned in the housing, the actuator having at least one element displaceable relative to the housing; a coupling element connecting the actuator to the recipient's ear; and a diaphragm positioned at an end of the housing to provide a hermetic seal between the coupling element and the housing, wherein the diaphragm has sufficient flexibility to permit the coupling element to transmit vibrations to or from the actuator, wherein a liquid is positioned around the displaceable element of actuator to dampen the frequency response of the actuator, and in certain aspects, to make the system insensitive to differences in pressure between inside and outside of the housing.2012-05-03
20120108888METHOD AND DEVICE FOR AROMATHERAPY - A fragrance dispensing device has a shape correlated with the fragrance being dispensed and when affixed with a nozzle can be inserted into a person's nose to provide aromatherapy or other herbal medications. The fragrance dispensing has a hollow body having a shape of a character and having a slit valve or a one-way valve disposed within the wall of the hollow body. A scented cartridge is inserted into the hollow body through the valve or some other resealable opening in the hollow body. The amount of fragrance dispensed is based, in part, upon the volume of the hollow body and the partial pressure of the fragrance within the cartridge. Where additional scent is desired, the hollow body can be repeatedly compressed to discharge additional discrete charges of fragrance into the environment.2012-05-03
20120108889UROLOGICAL DEVICE - A urological device comprises a urological valve for location in the bladder of a patient and a valve support stem for location in the urethra of a patient. The valve has a normally closed configuration to prevent flow from the bladder and an open configuration for fluid flow through the valve. The valve is automatically movable from the closed configuration to the open configuration in response to a pre-set hydrodynamic pressure applied for a pre-set time. In one case the valve has a plurality of valve leaflets with a region of co-aption between the valve leaflets. In the normally closed configuration the valve leaflets are engaged at the region of co-aption and in the open configuration the leaflets are separated at the co-aption region for fluid flow through the valve.2012-05-03
20120108890Sling Anchor System - The present disclosure is generally directed to surgical articles useful for implanting support members in patients. The articles disclosed herein include a support member, such as a sling for urinary incontinence, tissue anchors, filamentary elements for associating the support member with the anchors, and introducer needles for placing the anchors in a patient. The support members can also be configured for use in pelvic floor repair, such as for treating cystoceles, rectoceles, and enteroceles.2012-05-03
20120108891VEIN HARVESTING SYSTEM AND METHOD - A tissue illumination system and a method for harvesting a section of a blood vessel from a patient's body for further use. The tissue illumination system includes a light catheter inserted into a lumen of the blood vessel section to illuminate the vessel section and vessel side branches with an intensity which is visible to the physician from an exterior of the vessel section and also includes a viewing element insertable into the lumen and capable of viewing the illuminated vessel section. The tissue illumination system also includes at least one tool insertable into the lumen and used to harvest the vessel section.2012-05-03
20120108892GASTRIC BAND DEVICE AND METHOD - An apparatus for forming a gastric restriction includes an implantable band and at least one tab. In some versions, the at least one tab may serve to stabilize the apparatus as it forms a gastric restriction. In some versions, an opening may be formed in the tabs such that sutures may be used. In some versions, a tissue scaffold and/or matrix may be used on the implantable band and/or the tabs to facilitate long term support for the implantable band, such as by substantially preventing the implantable band from sliding along an axis defined by an anatomical structure about which the implantable band is wrapped.2012-05-03
20120108893DEPLOYABLE AND RETRACTABLE MEMBER FOR INJECTION PORT - An apparatus comprises a housing and one or more deployable protrusions. The apparatus defines a fluid reservoir and presents an upper surface. The housing is sized and configured to be implanted within a patient. The protrusions are selectively movable from a first position to a second position. The protrusions are at least partially retracted relative to the housing when the protrusions are in the first position. The protrusions are at least partially extended relative to the housing when the protrusions are in the second position. The protrusions may be in the form of substantially cylindraceous posts, semi-circular members, or other shapes. The protrusions may be actuated mechanically, electromechanically, or otherwise. The apparatus may be provided as an injection port, as part of a gastric band system or otherwise. The deployed protrusions may facilitate location of the implanted port through external palpation of the patient's abdomen.2012-05-03
20120108894IMPLANT FOR PELVIC ORGAN PROLAPSE REPAIR - A medical article 2012-05-03
20120108895IMPLANT FOR SUPPORTING THE PELVIC FLOOR - In one aspect, the present invention is directed to an implant (2012-05-03
20120108897Endoscopic Resection Devices and Related Methods of Use - A tissue resection system includes an endoscope including a stop ring extending about a distal portion thereof; a resection head mounted over the distal portion of the endoscope distally of the stop ring, the resection head including a resection chamber within an outer wall thereof; a first positioning mechanism abutting the stop ring to move the resection head relative to the endoscope between a first position in which a distal end of the resection head is proximal of a distal end of the endoscope and a second position in which the distal end of the resection head is distal of the distal end of the endoscope; and a second positioning mechanism moving a first portion of the outer wall relative to a second portion of the outer wall to open and close the resection chamber.2012-05-03
20120108898Tissue Vitality Comparator with Light Pipe with Fiber Optic Imaging Bundle - A surgical instrument having a tissue vitality comparator is provided to view images of tissue relative to the surgical instrument and compare the images with predetermined reference images. The surgical instrument includes a pair of jaws for capturing tissue and one or more light sources 2012-05-03
20120108899DEVICE FOR THE CONTROLLED INFUSION OF LIQUID FORMULATIONS IN TISSUES AND ORGANS IN CELLULAR THERAPEUTIC PROCEDURES - The present invention relates to a device for the controlled infusion of liquid formulations, especially formulations comprising cells, directly into tissues or organs, to be used in cellular therapeutic procedures related to ischemic or non-ischemic diseases. The device comprises an automatic dispenser (2012-05-03
20120108900MOUNTABLE CAMERA FOR LAPAROSCOPIC SURGERY - A laparoscopic surgical system comprising a camera and a base supporting the camera, and a camera insertion tool for inserting the camera into the body cavity. The camera is mountable to a surgical instrument inside the body cavity and releasable from the insertion tool after mounting to the surgical instrument.2012-05-03
20120108901MIRRORED ARTHROSCOPE - A surgical instrument includes an elongated tubular member defining a longitudinal axis and having a lumen extending therethrough. A light source is disposed within the elongated tubular member. The light source is configured to emit light from a distal end of the elongated tubular member. A mirror assembly is coupled to a distal end of the elongated tubular member. The mirror assembly is moveable between a retracted position and an extended position. In the retracted position, the mirror assembly is positioned adjacent an outer surface of the elongated tubular member. In the extended position, the mirror assembly extends distally from the elongated tubular member to re-direct light emitted by the light source.2012-05-03
20120108902ROTATE-TO-ADVANCE CATHETERIZATION SYSTEM - Apparatus comprising a tube sized to receive visualization apparatus; a deformable helical thread disposed on the exterior surface of the tube, the deformable helical thread (i) being transformable between a first configuration wherein the deformable helical thread comprises a reduced profile and/or a reduced rigidity and a second configuration wherein the deformable helical thread comprises an expanded profile and/or an increased rigidity, and (ii) when in its second configuration, having a sufficient structural integrity, and a sufficient surface profile, such that when the tube is disposed in a bodily passageway so that the deformable helical thread engages the interior wall of the bodily passageway, rotation of the tube will induce a relative movement between the tube and the wall of the bodily passageway; and a thread varying element dynamically varying at least one of the height of the deformable helical thread and the rigidity of the deformable helical thread.2012-05-03
20120108903INFRARED ENDOSCOPIC BALLOON PROBES - Balloon probes, adapted for use in endoscopy and other medical procedures, are useful to obtain spectroscopic information reflected or emitted from a tissue of interest in the infrared spectral region. The information collected by the probe is useful in the diagnosis and treatment of disease. The invention also relates to methods utilizing these probes to analyze a surface of interest, in a minimally invasive manner, in connection with the diagnosis and treatment of disease.2012-05-03
20120108904CLEANER FOR ENDOSCOPE - A surgical scope for viewing a surgical site of a patient including an elongated tube, a viewing lens having an outer surface positioned at the distal portion of the scope, and a lens cleaner positioned at the distal portion and translatable between a first position and a second position. The lens cleaner includes an arcuate wiper having a complementary shape to the shape of the lens. An actuator is spaced proximally of the wiper and actuable to translate the wiper along the outer surface of the lens.2012-05-03
20120108905PORTAL APPARATUS WITH A CONTOURED COMPLIANT SEAL - The present disclosure relates to a contoured instrument seal for arthroscopic, laparoscopic and endoscopic surgery. The contoured instrument seal includes a body, an annular inner edge, an annular outer edge, and one or more raised concentric rings, e.g., having a spiral shape. The body includes a top surface and a bottom surface. The annular inner edge defines an opening adapted to receive a surgical instrument. The annular outer edge may be adapted to mechanically mount to an inner portion of a seal housing. The raised concentric ring is defined on a surface of the resilient body between the annular inner edge and the annular outer edge.2012-05-03
20120108906SURGICAL RETRACTOR WITH GEL PAD - A surgical access device has a surgical retractor having a noncompliant outer ring with an annular axis, an inner ring, and a sleeve coupling the outer ring to the inner ring. The noncompliant outer ring is adapted to roll over itself around the annular axis to roll the sleeve around the outer ring to retract and seal an opening in a biological body wall. The access device may include a lid adapted for being coupled to the noncompliant outer ring of the surgical retractor. The outer ring of the surgical retractor has a cross-sectional shape that prohibits the lid from being partially or incorrectly coupled to the outer ring of the surgical retractor.2012-05-03
20120108907Vaginal Speculum Provided With An Automatically Actuated Illumination System - The present invention relates to the field of gynecological instruments. A disposable speculum is provided with a cylindrical filament containing an optical fiber fitted with a small aligning wing nut (2012-05-03
20120108908ENHANCED SENSING BY AN IMPLANTABLE MEDICAL DEVICE IN THE PRESENCE OF AN INTERFERING SIGNAL FROM AN EXTERNAL SOURCE - An implantable medical device (IMD) adjusts a sensing configuration of a sensing module prior to or immediately subsequent to entering an environment having an external source that generates the interfering signal. The IMD may, for example, adjust a sampling frequency, resolution, input range, gain, bandwidth, filtering parameters, or a combination of these or other sensing parameters of the sensing module. These adjustments enable the sensing module to obtain a more detailed representation of the sensed signals, including the noise components of the sensed signals caused by the interfering signal. Without having an adequate representation of the noise components of the sensed signal, it is difficult to separate the noise components of the sensed signal from the cardiac electrical signal.2012-05-03
20120108909Assessment and Rehabilitation of Cognitive and Motor Functions Using Virtual Reality - A user-friendly reliable process is provided to help diagnose (assess) and treat (rehabilitate) impairment or deficiencies in a person (subject or patient) caused by a traumatic brain injury (TBI) or other neurocognitive disorders. The economical, safe, effective process can include: generating and electronically displaying a virtual reality environment (VRE) with moveable images; identifying and letting the TBI person perform a task in the VRE; electronically inputting and recording the performance data with an electronic interactive communications device; electronically evaluating the person's performance and assessing the person's impairment by electronically determining a deficiency in the person's cognitive function (e.g. memory, recall, recognition, attention, spatial awareness) and/or motor function (i.e. motor skills, e.g. balance) as a result of the TBI or other neurocognitive disorder.2012-05-03
20120108910PERFORMING MEASUREMENT OF A SUBJECT - A method of performing measurement of a subject comprises measuring a physiological parameter of a subject, deriving data from the measured parameter, optionally, obtaining metadata relating to the measurement of the physiological parameter, determining the quality of the derived data from the derived data and/or the obtained metadata, and if the determined quality matches a predefined criteria, performing a predefined corrective action. In one embodiment, the method further comprises calculating one or more qualifiers from the derived data and/or from the obtained metadata, and wherein the step of determining the quality of the derived data comprises determining the quality of the derived data from the calculated qualifiers.2012-05-03
20120108911MEDICAL APPARATUS - The present invention relates to medical apparatus for monitoring one or more physiological conditions of a patient and a method for monitoring one or more physiological conditions of a patient. Apparatus for measuring medical data is described, comprising: at least one medical data gathering module, at least one microprocessor, and further wherein the apparatus further comprises a medical data handling module separate from the at least one microprocessor for buffering medical data transfer between the medical data gathering module and the microprocessor and optionally further wherein the medical data handling module can gather and store data in predetermined groups of data and the microprocessor can retrieve data from the medical data handling module in one or more multiples of predetermined groups of data. A method for measuring medical data is described, comprising: providing at least one medical data gathering module; providing at least one microprocessor; providing a data handling module separate from the at least one microprocessor; buffering medical data transfer between the medical data gathering module and the microprocessor optionally by gathering and storing data in predetermined groups of data and retrieving data from the medical data handling module in one or more multiples of predetermined groups of data.2012-05-03
20120108912METHOD AND SYSTEM FOR DETERMINING WHEN TO REPOSITION A PHYSIOLOGICAL SENSOR - A sensor may be placed on a patient to obtain physiological measurements. The application of the sensor on the patient may start a timer set to run for a given time interval. If the sensor is repositioned before the interval is expired, the timer is reset. If the time expires without the sensor being repositioned, a caregiver is prompted to reposition the sensor.2012-05-03
20120108913Systems and Methods for Providing a Continual Measurement of Health - A system for improving hospital patient care by generating a Health Score. The system includes an interface module for receiving incoming medical data from a patient, a transformation module for transforming each of the medical datum into a transformed Health Score value, and a combination module for combining the transformed Health Score values corresponding to each of the medical datum into a single Health Score. A presentation and comparison module displays the Health Score as a Health Score plot over a predetermined time frame, such that a user may identify health trends in a patient by evaluating said Health Score plot.2012-05-03
20120108914SYSTEM AND METHOD FOR ASSESSMENT OF HEALTH RISKS AND VISUALIZATION OF WEIGHT LOSS AND MUSCLE GAIN - The present system combines image morphing technology, exercise programming, supplement sales, and motivational techniques into one product. Users begin by entering their current measurements, measurement goals and current picture into the system, preferably via a Web site. The picture is segmented into body components, and each affected segment is morphed based upon the measurements, goals, and the segment's responsiveness to weight loss in order to create a modified image representative of the user in a post-regimen condition. This system helps health and fitness businesses obtain new members and retain existing members by showing the members how they will look after following a specific regimen of diet and/or exercise. The system also predicts health risks of diabetes, heart disease, and stroke associated with the user's pre-regimen and post-regimen conditions.2012-05-03
20120108915POSTURE-INDUCED CHANGES TO PHYSIOLOGICAL PARAMETERS - Methods and devices for analyzing posture-induced changes to physiological parameters of a patient (e.g., ejection time, heart rate, etc.) to provide an assessment of one or more conditions of the patient.2012-05-03
20120108916FITNESS SCORE ASSESSMENT BASED ON HEART RATE VARIABILITY ANALYSIS DURING ORTHOSTATIC INTERVENTION - This invention relates to fitness monitors and the like. This invention is more particularly directed to a device and a method for facilitating quantitative evaluation of level of physical fitness (fitness score) including a PC or handheld, or watch type electronic device having input and output means based on formulas for calculating level of physical fitness through heart rate variability analysis during orthostatic intervention by assessing two main parameters, such as level of adaptation reserve and wellness level.2012-05-03
20120108917PATIENT MONITORING SYSTEMS AND METHODS - An adherent patient device is configured to adhere to the skin of the patient and measure electrocardiogram data, impedance data, accelerometer data, blood oxygen data and temperature data. The adherent device can communicate wirelessly with gateways and a local processor system, such that the patient can wander about the hospital and update the monitoring station with the patient data when the patient is ambulatory. The local processor system can be configured to customize alerts for the patient, for example to notify automatically a specialist in response to a special condition of the patient. The adherent device may comprise a unique adherent device identifier such that the customized alert can be sent based on the unique device identifier. Each of the gateways can be carried and may comprise a unique gateway identifier, such that the unique device identifier and the unique gateway identifier can be used to locate the ambulatory patient.2012-05-03
20120108918Acoustic Palpation Using Non-Invasive Ultrasound Techniques for Identification of Target Sites and Assessment of Chronic Pain Disorders - Methods and systems for identifying and spatially localizing tissues having certain physiological properties or producing certain biological responses, such as the sensation of pain, in response to the application of intense focused ultrasound (acoustic probing or palpation) are provided. In some embodiments, targeted acoustic probing is employed to identify the scope and severity of chronically painful sensitized tissue areas, and of chronic pain disorders. In other applications, targeted acoustic probing is used to localize nerves and other sensitized tissues for guidance of needles and other delivery devices, and for delivery of anesthetic, analgesic or therapeutic compositions.2012-05-03
20120108919METHOD AND SYSTEM FOR MONITORING OXYGENATION LEVELS OF A COMPARTMENT FOR DETECTING CONDITIONS OF A COMPARTMENT SYNDROME - A method and system for continually monitoring oxygenation levels in real-time in compartments of an animal limb, such as in a human leg or a human thigh or a forearm, can be used to assist in the diagnosis of a compartment syndrome. The method and system can include one or more near infrared compartment sensors in which each sensor can be provided with a compartment alignment mechanism and a central scan depth marker so that each sensor may be precisely positioned over a compartment of a living organism. The method and system can include a device for displaying oxygenation levels corresponding to respective compartment sensors that are measuring oxygenation levels of a compartment of interest. The method and system can also monitor the relationship between blood pressure and oxygenation levels and activate alarms based on predetermined conditions relating to the oxygenation levels or blood pressure or both.2012-05-03
20120108920ADHERENT DEVICE WITH MULTIPLE PHYSIOLOGICAL SENSORS - An adherent device to monitor a patient for an extended period comprises a breathable tape. The breathable tape comprises a porous material with an adhesive coating to adhere the breathable tape to a skin of the patient. At least one electrode is affixed to the breathable tape and capable of electrically coupling to a skin of the patient. A printed circuit board is connected to the breathable tape to support the printed circuit board with the breathable tape when the tape is adhered to the patient. Electronic components electrically are connected to the printed circuit board and coupled to the at least one electrode to measure physiologic signals of the patient. A breathable cover and/or an electronics housing is disposed over the circuit board and electronic components and connected to at least one of the electronics components, the printed circuit board or the breathable tape.2012-05-03
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