18th week of 2012 patent applcation highlights part 52 |
Patent application number | Title | Published |
20120107716 | SOLID OXIDE FUEL CELL - A solid oxide fuel cell includes two or more power generating elements each having a cathode, an anode, and an electrolyte layer placed between the cathode and the anode; an interconnector electrically connecting the power generating elements and containing a chromite-based material; and a sealing portion provided between the electrolyte layer and the interconnector and not containing either Ni or ZrO | 2012-05-03 |
20120107717 | METHOD FOR FABRICATION OF ELECTROCHEMICAL ENERGY CONVERTER AND THE ELECTROCHEMICAL ENERGY CONVERTER - The method for fabrication of the electrochemical energy converter characterised in that, cermet composition ( | 2012-05-03 |
20120107718 | FUEL CELL SEALING STRUCTURE - A fuel cell sealing structure has a power generating body, and first and second separators arranged in both sides in a thickness direction of the power generating body. On a surface in one side in a thickness direction of the first separator, formed integrally first and second sealing protrusions respectively brought into close contact with an outer peripheral portion of the power generating body and the second separator in an outer peripheral side of the first sealing protrusion, and a short circuit prevention rib protruding in line with the first and second sealing protrusions by an electrically insulating rubber-like elastic material. On a surface in another side thereof, formed integrally a third sealing protrusion brought into close contact with a surface in an opposite side to the power generating body in the second separator, by the electrically insulating rubber-like elastic material. | 2012-05-03 |
20120107719 | ELECTRODE CATALYST FOR MEMBRANE ELECTRODE OF FUEL CELL AND ITS METHOD OF PREPARATION AND FUEL CELL MEMBRANE ELECTRODE - This invention discloses an electrocatalyst for membrane electrode assembly, and its preparation method, as well as a fuel cell membrane electrode assembly. An electrocatalyst for fuel cell application, it is featured that the electrocatalyst is prepared by supporting precious metal (10-60 wt %) on a composite carrier which is prepared by depositing water-containing substance (0.3-10 wt %) on carbon material; Using the catalyst invented by this invention as anode catalyst, an fuel cell membrane electrode assembly with excellent non-humidification performance can be prepared by normal procedures. No need to construct a water retention layer, no need to add water retention material in proton exchange membrane, it avoids the possible problems caused by adding water attention material into proton exchange membrane or inserting a water retention layer. The approach suggested by this invention is a simple and effective approach to realize non-humidification membrane electrode assembly. | 2012-05-03 |
20120107720 | SELF-SUPPORTING DYNAMIC POLYMER MEMBRANE, METHOD OF PREPARATION, AND USES - The present invention relates to self-supporting dynamic polymer membranes (called “dynamer” membranes) of the polyimine type, to their method of preparation and to their use in separation processes, especially for separating gaseous CP species. | 2012-05-03 |
20120107721 | POLYMER ELECTROLYTE MEMBRANE, AND MEMBRANE ELECTRODE ASSEMBLY AND POLYMER ELECTROLYTE FUEL CELL USING THE SAME - Disclosed is a fuel cell in which a membrane electrode assembly less undergoes increase in ion conduction resistance, and a polymer electrolyte membrane less undergoes deterioration. Specifically, the polymer electrolyte membrane includes a first membrane and a second membrane being two different membranes composed of polymer electrolytes having different ion-exchange capacities, in which the first membrane has an area of one surface thereof equal to or larger than an area of one surface of an anode or a cathode, and the second membrane has an area of one surface thereof smaller than that of the first membrane and is arranged in a gas inflow region on a side being in contact with the cathode. The second membrane has an ion-exchange capacity smaller than that of the first membrane or has a number-average molecular weight larger than that of the first membrane. | 2012-05-03 |
20120107722 | SEPARATOR AND FUEL CELL USING THE SAME - A separator for a fuel cell includes a metal separator (metal substrate) having projections formed by ribs, and porous members provided in a plurality of flow passages partitioned by the projections, in which a hydrophilic portion is provided in a center part of a cross section orthogonal to a flow direction in the porous member, and a water repellent portion is provided in at least a part of portions in contact with wall surfaces of the flow passage within a range of the cross section. | 2012-05-03 |
20120107723 | PORE FORMATION BY IN SITU ETCHING OF NANOROD PEM FUEL CELL ELECTRODES - The invention includes a method for use in creating electrochemical electrodes including removing a supporting structure in situ after the assembly of the electrochemical cell. | 2012-05-03 |
20120107724 | ELECTRODE CATALYST FOR FUEL CELL, METHOD FOR PRODUCING THE SAME, AND POLYMER ELECTROLYTE FUEL CELL USING THE SAME - An electrode catalyst for a fuel cell consists principally of a carbon support, and a platinum catalyst or a platinum-alloy catalyst supported on the carbon support. In the electrode catalyst, at least 0.7 mmol of an acid per gram of the electrode catalyst is present on the carbon support. | 2012-05-03 |
20120107725 | Solid Polymer Electrolyte Composition, and Ion-Exchange Membrane, Membrane Electrode Assembly and Fuel Cell - To provide a solid polymer electrolyte composition that can improve oxidation resistance without causing decrease in proton conductivity, elution of added components and the like, and an ion-exchange membrane, a membrane electrode assembly and a fuel cell, each using the composition. It is possible to obtain a solid polymer electrolyte composition having excellent oxidation resistance without causing decrease in proton conductivity, elution of added components and the like, by mixing an aromatic hydrocarbon-based polymer electrolyte, a phosphorus-containing polymer compound and a metallic element. | 2012-05-03 |
20120107726 | PROCESS FOR PRODUCING FLUORINE CONTAINING POLYMER - According to this invention, a process for producing fluorine containing polymer to obtain composite polymer electrolyte composition having excellent ion transport number, that is, ion transfer coefficient, for example, excellent transport number of lithium ion, is provided. | 2012-05-03 |
20120107727 | FUEL CELL MODULE AND MANUFACTURING METHOD OF THE SAME - A fuel cell module and a method of manufacturing the same. A fuel cell module including a unit cell in which a first electrode layer, an electrolyte layer, and a second electrode layer are sequentially laminated, wherein one of the first electrode layer and the second electrode layer includes a first region coated with a first electrode material layer having a first ionic conductivity, a second region coated with a second electrode material layer having a second ionic conductivity, and a third region coated with a third electrode material layer having a third ionic conductivity, and a method of manufacturing the same are provided. A temperature gradient difference of a unit cell is reduced so that more uniform performance of the unit cell may be achieved. The fuel cell module may be driven at low temperature and durability thereof may be improved. | 2012-05-03 |
20120107728 | NON-AQUEOUS ELECTROLYTE AND LITHIUM AIR BATTERY INCLUDING THE SAME - A non-aqueous electrolyte and a lithium air battery including the same. The non-aqueous electrolyte may include an oxygen anion capturing compound to effectively dissociate the reduction reaction product of oxygen formed during discharging of the lithium air battery, reduce the overvoltage of the oxygen evolution reaction occurring during battery charging, and enhance the energy efficiency and capacity of the battery. | 2012-05-03 |
20120107729 | GATE CD CONTROL USING LOCAL DESIGN ON BOTH SIDES OF NEIGHBORING DUMMY GATE LEVEL FEATURES - A method of forming an IC including MOS transistors includes using a gate mask to form a first active gate feature having a line width W | 2012-05-03 |
20120107730 | RECORDING MEDIUM RECORDING PROGRAM FOR GENERATING MASK DATA, METHOD FOR MANUFACTURING MASK, AND EXPOSURE METHOD - A mask includes a main pattern for resolving a target pattern to be formed on a substrate and an auxiliary pattern not resolving. Values of parameters of the main pattern and the auxiliary pattern are set. An image is calculated that is formed when the main pattern and the auxiliary pattern determined by the values of the parameters of the main pattern and the auxiliary pattern are projected by a projection optical system. Based on a result of the calculation that is performed by modifying the values of the parameters of the main pattern and the auxiliary pattern, the values of the parameters of the main pattern and the auxiliary pattern are determined to generate data of the mask including the main pattern and the auxiliary pattern determined. | 2012-05-03 |
20120107731 | PHOTOMASK - A photomask includes a transparent substrate for passage of an exposure light, and a plurality of photomask pattern units formed on a surface of the transparent substrate. Each of the photomask pattern units includes a first light-blocking layer connected to the surface of the transparent substrate, and a second light-blocking layer formed on a surface of the first light-blocking layer opposite to the transparent substrate. The first and second light-blocking layers block the exposure light, or permit passage of light energy lower than threshold energy of photoresist on the substrate. | 2012-05-03 |
20120107732 | CURABLE COMPOSITIONS, METHOD OF COATING A PHOTOTOOL, AND COATED PHOTOTOOL - A curable composition comprises: an epoxy silane represented by formula X—Si(OR | 2012-05-03 |
20120107733 | REFLECTIVE MASK BLANK FOR EUV LITHOGRAPHY - Provision of a reflective mask blank for EUV lithography having an absorber layer having optical constants suitable for reducing the film thickness. | 2012-05-03 |
20120107734 | METHODS OF FORMING SHEETING WITH COMPOSITE IMAGES THAT FLOAT AND SHEETING WITH COMPOSITE IMAGES THAT FLOAT - Microlens sheetings with different types of composite images are disclosed, in which the composite image floats above, in, or below the sheeting, or some combination. One type of composite image may be viewable to the unaided eye or an observer and another type of composite image is viewable only to the aided eye of an observer. Methods for providing such an imaged sheeting are also disclosed. | 2012-05-03 |
20120107735 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS - An electrophotographic photosensitive member comprises a conductive support, an intermediate layer provided on the conductive support, and a photosensitive layer provided on the intermediate layer, in which at least one of the intermediate layer and the photosensitive layer comprises a compound represented by the following formula (1): | 2012-05-03 |
20120107736 | PROCESS FOR PREPARING POLYMERIZED TONER - The present invention relates to a process for preparing a polymerized toner, and in particular to a process for preparing a polymerized toner and a polymerized toner prepared therefrom, wherein a certain block copolymer and copper phthalocyanine are used within a predetermined range of the amounts for a carbon black dispersant during a suspension polymerization, thereby making it possible to realize a narrow particle sizes distribution, high transcription efficiency, and an enhanced image concentration. | 2012-05-03 |
20120107737 | Toner Compositions - Toner particles are provided which may, in embodiments, include a core and a shell formed in situ. The resins utilized to form the core, the shell, or both, may be contacted with a water soluble initiator. The resin, in embodiments present in the shell, cross-links at a temperature near the temperature for coalescence, and may prevent a crystalline resin in the core from migrating to the toner surface. | 2012-05-03 |
20120107738 | TAGGENT FLAKES FOR COVERT SECURITY APPLICATIONS HAVING A SELECTED SHAPE - A plurality of flakes are provided that can be used in ink or paint wherein the flakes are of a size that requires magnification to see their shape. The flakes are in the form of regular polygons, such as squares, triangle or rectangles. A breaking or grinding process is used to break a foil into these shaped flakes and frames or walls are provided within the foil sheet so as to delineate the shapes and these lines provided by frames or walls will facilitate breakage in a preferred manner such that the flakes break into selected shaped polygons. Due to the breakage or grinding process, small remnants are typically still present on the shaped flakes as a result of the way in which the foil and flakes are broken, however with magnification, one can see the resultant regular polygonal shape. To clearly see the remnants one requires increased magnification and the remnant itself provides a type of signature. It can be seen as a taggent within a taggent. | 2012-05-03 |
20120107739 | ELECTROSTATIC LATENT IMAGE DEVELOPER, IMAGE FORMING APPARATUS, PROCESS CARTRIDGE AND IMAGE FORMING METHOD - The present invention provides an electrostatic latent image developer used in an image forming apparatus including: an image holding member; a charging unit; a latent image forming unit; a developing unit which stores the electrostatic latent image developer and includes a developer holding member, wherein the developing unit develops the electrostatic latent image formed on the image holding member by bringing a magnetic brush, which is formed on a surface of the developer holding member by the electrostatic latent image developer, into contact with the image holding member, to form a toner image; a transfer unit; a cleaning unit; and a lubricant applying unit, wherein the electrostatic latent image developer contains a toner having a 50% integrated volume particle diameter of from 3.0 to 6.0 μm, and a carrier having a mean magnetization of 5.0×10 | 2012-05-03 |
20120107740 | MAGNETIC TONER COMPOSITIONS - The present disclosure relates to a process for preparing a polyester based magnetic toner composition. The toner composition includes one or more polyester amorphous binder resins, optionally a cystalline polyester resin, and spherical ferromagnetic particles. In embodiments, the toner is prepared from ferromagentic particles that have been previously encapsulated in an amorphous resin, a crystalline resin or a wax. In yet other embodiments, the process may be conducted under an inert gas such as argon to avoid oxidation of the ferromagnetic particles during toner preparation. | 2012-05-03 |
20120107741 | ELECTROSTATIC CHARGE IMAGE DEVELOPING TONER AND METHOD OF MANUFACTURING THE SAME - Provided is a method of manufacturing toner by which the toner capable of forming high quality images and reproducing high density gradation, which exhibits an excellent high-temperature offsetting property together with excellent low-temperature fixability, and provides appropriate gloss with respect to images to be formed, can be stably prepared; and also provided is the toner. After conducting a step in which particles made of at least a crystalline polyester resin are coagulated to form core coagulated particles, and an unsaturated amorphous polyester resin particle is attached onto the surface of each of the core coagulated particles to form core-shell type coagulated particles, radical polymerization reaction is conducted by acting a radical polymerization initiator on the foregoing core-shell type coagulated particles to conduct a step in which a layer made of a crosslinking amorphous polyester resin is formed on the surface of each of the core coagulated particles. | 2012-05-03 |
20120107742 | METHOD AND PHOTORESIST WITH ZIPPER MECHANISM - The present disclosure provides a resist utilized in a photolithography patterning process. The resist includes a polymeric material having a plurality of zipper molecules, each including a first zipper portion and a second zipper portion, wherein the first and second zipper portions each include a plurality of zipper branches bonded together in pairs and cleavable to one of thermal energy, radiation energy, and chemical reaction. | 2012-05-03 |
20120107743 | LITHOGRAPHY USING PHOTORESIST WITH PHOTOINITIATOR AND PHOTOINHIBITOR - Technologies are generally described for a photoresist and methods and systems effective to form a pattern in a photoresist on a substrate. In some examples, the photoresist includes a resin, a photoinitiator and a photoinhibitor. The photoinitiator may be effective to generate a first reactant upon the absorption of at least one photon of a particular wavelength of light. The first reactant may be effective to render the resin soluble or insoluble in a photoresist developer. The photoinhibitor may be effective to generate a second reactant upon the absorption of at least one photon of the particular wavelength of light. The second reactant may be effective to inhibit the first reactant. | 2012-05-03 |
20120107744 | RESIST COMPOSITION, METHOD OF FORMING RESIST PATTERN, NOVEL COMPOUND AND ACID GENERATOR - A resist composition containing a base component (A) which exhibits changed solubility in a developing solution under the action of acid, and an acid generator component (B) which generates acid upon exposure, wherein the acid generator component (B) includes an acid generator (B1) having a group represented by general formula (b1-1) shown below in the cation moiety. | 2012-05-03 |
20120107745 | VIA STRUCTURE IN MULTI-LAYER SUBSTRATE AND MANUFACTURING METHOD THEREOF - Disclosed is a via structure in a multi-layer substrate, comprising a first metal layer, a dielectric layer and a second metal layer. The first metal layer has an upper surface. The dielectric layer covers the first metal layer in which a via is opened to expose the upper surface. The second metal layer is formed in the via and contacts an upper surface and an inclined wall of the via. A contacting surface of the second metal layer has a top line lower than the upper edge of the inclined wall. Alternatively, the second metal layer can be formed on the dielectric layer as being a metal line simultaneously as formed in the via as being a pad. The metal line and the pad are connected electronically. The aforesaid metal second layer can be formed in the via and on the dielectric layer by a metal lift-off process. | 2012-05-03 |
20120107746 | METHOD FOR MANUFACTURING INKJET RECORDING HEAD - A method for manufacturing an inkjet recording includes forming a photo-cationic polymerizable resin layer containing a photo-cationic polymerizable resin material on a substrate; performing pattern exposure of the photo-cationic polymerizable resin layer to form a latent image of a fine pattern including an ejection port; forming a water repellent layer containing a water repellent material capable of forming a bond in reaction with the photo-cationic polymerizable resin material on the photo-cationic polymerizable resin layer; developing the photo-cationic polymerizable resin layer to thereby remove a non-exposed portion of the photo-cationic polymerizable resin layer and remove a water repellent layer portion corresponding to the non-exposed portion to thereby form the fine pattern; and curing the photo-cationic polymerizable resin layer by heat treatment to form a member provided with the fine pattern and promote a reaction of the photo-cationic polymerizable resin material and the water repellent material. | 2012-05-03 |
20120107747 | METHOD OF LITHOGRAPHY - A lithography method of manufacturing integrated circuits is disclosed. A photoalignment layer is formed on a substrate. A treatment is performed to reorganize and align the photoalignment molecules. A photoresist layer may be formed on the photoalignment layer in a bi-layer separate coating or with the photoalignment layer in a bound-bind structure. | 2012-05-03 |
20120107748 | DRAWING APPARATUS AND METHOD OF MANUFACTURING ARTICLE - A drawing apparatus, that performs drawing on a substrate using an array of charged particle beams, includes a projection system and a controller. The projection system is configured such that the array includes a plurality of sub arrays arranged discretely on the substrate with a space between the sub arrays in a predetermined direction, and a first width of the space in the predetermined direction is n1/n2 times (each of n1 and n2 is a positive integer) a second width of the sub array in the predetermined direction. The controller is configured to control the projection system and a driving mechanism such that drawing is performed in order with the plurality of sub arrays for [n1+n2] sets of drawing regions that are shifted from one another by as much as [1/n2] times the first width so that drawing is performed for a shot region on the substrate. | 2012-05-03 |
20120107749 | RESIST PATTERN FORMING METHOD AND DEVELOPER - There are provided a method of forming a resist pattern, comprising the steps of forming a resist film containing a specific calixarene derivative on a substrate; forming a pattern latent image by selectively exposing the resist film to a high-energy beam; and developing the latent image by removing parts not exposed to the high-energy beam of the resist film with a developer containing at least one fluorine-containing solvent selected form the group consisting of a fluorine-containing alkyl ether and a fluorine-containing alcohol, and the fluorine-containing solvent as a resist developer. | 2012-05-03 |
20120107750 | SYSTEM AND METHOD FOR IGNITING A COMBUSTOR - An ignition system for a combustor includes an access port through a wall of the combustor and a laser outside the combustor and aligned with the access port to generate a beam along a path. A lens in the path of the beam focuses the beam at a focal point inside the combustor, and a shutter has a first position in the path and a second position out of the path. A method for igniting a combustor includes generating a beam along a path, focusing the beam to a focal point inside the combustor, and moving a shutter from a first position in the path to a second position outside of the path. | 2012-05-03 |
20120107751 | METHOD FOR SUPPRESSING ADHESION OF ASH AND DEVICE FOR SUPPRESSING ADHESION OF ASH IN BOILER - In order to stably operate a boiler using several kinds of solid fuels including depleted ash as fuels, adhesion of ash is suppressed. A calculator ( | 2012-05-03 |
20120107752 | SYSTEMS, METHODS, AND APPARATUS FOR DETERMINING AIRFLOW THROUGH A BURNER - Certain embodiments of the invention may include systems, methods, and apparatus for determining airflow through a burner. According to an example embodiment of the invention, a method is provided for determining airflow through a burner. The method includes installing a first end of an inlet pressure transmission tube in an air inlet region of a furnace burner system, installing a first end of a burner pressure transmission tube in a burner exit region of the furnace burner system, connecting a second end of the inlet pressure transmission tube to a first pressure sensor, connecting a second end of the burner pressure transmission tube to a second pressure sensor, measuring the differential pressure between the first and second pressure sensors, and determining airflow based at least in part on the measured differential pressure. | 2012-05-03 |
20120107753 | BURNER CONTROL SYSTEMS AND METHODS OF OPERATING A BURNER - Burner control systems and methods of operating a burner are for a large boiler such as might be used in hospitals, hotels, offices or other large commercial or domestic premises. | 2012-05-03 |
20120107754 | COMBUSTOR CONFIGURATIONS - The present specification generally relates to improvements to combustors such as burners and engines. In one aspect, the specification presents an acoustically enhanced ejector system which can be used as part of an intake system for a combustor. In another aspect, the specification teaches the use of a combustor combustion chamber as an oscillator to magnify a harmonic frequency of a pulsating frequency of the combustor. In still other aspects, the specification presents a combustion chamber having an inlet with a plurality of tangentially spaced apertures, and an in-line intake system connected to the apertures. | 2012-05-03 |
20120107755 | BURNER APPARATUS - This burner apparatus (S | 2012-05-03 |
20120107756 | Survival light - Survival light consisting of a disk with wick installed on the top floating on the surface of a combustible fluid that can reach and be sucked up by the wick through vertical holes penetrating the disk and through horizontal channels leading the combustible fluid from the periphery of the disk to the central area where the wick is installed and where the combustible fluid is a layer on top of a non-combustible fluid such as water. | 2012-05-03 |
20120107757 | Method and Apparatus for Thermally Processing Plastic Discs, in particular Mould Wafers - The present invention provides a method and apparatus for thermally processing plastic discs, in particular mould wafers. The method comprises the following steps: clamping a mould wafer ( | 2012-05-03 |
20120107758 | DIRECT SPRAY COOLING FOR LIMESTONE PREHEATERS - A preheating apparatus for particulate material using hot kiln gases to preheat the particular material. The apparatus has a means to cool the hot kiln gases prior to the gases being exhausted from the preheating apparatus. | 2012-05-03 |
20120107759 | FLAMELESS IMPINGEMENT PREHEATING FURNACE - A heating apparatus for charge material includes a preheater having a housing with a combustion chamber therein constructed and arranged to receive the charge material, at least one oxy-fuel burner mounted to the housing for providing a combustion flame to the combustion chamber wherein a combustion atmosphere is created to provide heat sufficient to increase a temperature of the charge material, a fuel supply and an oxidant supply connected to the at least one oxy-fuel burner, an exhaust in communication with the combustion chamber for removing a portion of the combustion atmosphere from the combustion chamber; and a melter separate from the preheater for coaction therewith to receive the heated charge material for being melted in the melter. | 2012-05-03 |
20120107760 | SELF-LIGATING BRACKET - The invention relates to a bracket ( | 2012-05-03 |
20120107761 | DEVICE FOR GENERATING GASEOUS SPECIES - The present invention provides a device | 2012-05-03 |
20120107762 | Method And System For Operating A Medical, In Particular A Dental, Handpiece - A method and corresponding system for operating a dental handpiece, wherein the handpiece comprises a motor for driving a tool. the method comprises (a) sequentially capturing values of a physical parameter, which—at least approximately—represent the power or energy fed to the motor, (b) forming an integration value by integrating the values captured in (a), and (c) automatically reducing a power or energy fed to the motor if the integration value formed in (b) exceeds an upper threshold value. The integration value formed in (b) represents a measure of the power integrated over time and can thus be used at least approximately as a measure of the temperature of the instrument. The automatic reduction in the power or energy fed to the motor performed in (c) can therefore effectively act against a further increase in temperature or allow cooling if the temperature of the instrument exceeds an upper threshold value. In this manner, the risk of damage due to excessive temperature of the instrument can be effectively reduced. | 2012-05-03 |
20120107763 | SYSTEM , METHOD AND ARTICLE FOR MEASURING AND REPORTING CRANIOMANDIBULAR BIOMECHANICAL FUNCTIONS - The present invention provides a motion analysis system for measuring the relative function of one anatomical structure to another based on optical fiducial markers tracked in a series of images and in turn data, where the components of hard and soft tissue are used in analysis and where the image data can be compared in a time series such that probabilities of involvement with various tissues can be correlated to the image data. | 2012-05-03 |
20120107764 | METHOD FOR PREPARING A SURGICAL MASK FOR THE INSTALLATION OF DENTAL IMPLANTS - A method for preparing a surgical mask for the installation of a dental implant, including: arranging a pliable material on a support ( | 2012-05-03 |
20120107765 | ATOMIZED LIQUID ORAL CLEANING APPLIANCE - The oral cleaning appliance includes an assembly for generating low-pressure bursts of gas in the range of 2-7 bar, directed to a mixing chamber portion of the appliance. A pump provides successive doses of liquid to the mixing chamber. The mixing chamber includes an outlet for liquid droplets produced by the interaction of the gas and the liquid in the mixing chamber. The gas inlet line to the mixing chamber has an internal diameter in the range of 1-5 mm. The center line of the gas inlet line is offset from the center line of the liquid droplet outlet line by a distance in the range of 1-5 mm. | 2012-05-03 |
20120107766 | ENDODONTIC SYSTEM AND METHOD - The present invention provides a system for the endodontic treatment of a root canal, comprising
| 2012-05-03 |
20120107767 | Ultrasonic Dental Treatment System - The present invention is a personal ultrasonic dental hygiene device. A handle with an ultrasonic transducer is provided with differing dental hygiene attachments for personal use. The device may be powered through a battery or through direct wall socket communication. A variety of controls may be provided to adjust ultrasonic frequency and treatment time. | 2012-05-03 |
20120107768 | DENTAL PROTECTIVE DEVICE AND METHOD OF USE - The present invention relates generally to the protection of a wearer of an installed dental appliance, such as braces, against pain, discomfort and injury due to the lips, cheek and tongue of the wearer rubbing against a rough or sharp edge of the braces. A dental protective device is used for protection against this discomfort and injury from the braces. The dental protective device is a moisture-activated self-adhering protective strip loosely adhered to a backing strip and packaged in a sealed foil pouch. In use, the protective strip is peeled away from the backing and applied to an area in need of protection. | 2012-05-03 |
20120107769 | DENTAL PROPHYLAXIS ANGLE AND HANDPIECE ASSEMBLY - A dental prophylaxis angle and handpiece assembly for cleaning and polishing teeth is provided. The dental prophylaxis angle is removably attached to the dental handpiece by an interlocking mechanism that includes extension locking tabs, a locking annular member, and an interlocking drive member in the handpiece. The prophy angle is securely snap-fitted onto the handpiece and locked in place so that it has minimal lateral movement. After the prophy angle has been used to treat a patient, it can be removed easily from the handpiece and disposed thereof. | 2012-05-03 |
20120107770 | AREA-SPECIFIC DENTAL INSTRUMENT - An area-specific dental instrument is provided, which comprises an arcuate S-shaped shank and an arcuate blade further comprising a sharpened convex surface. This instrument can be capable of cleaning plaque and calculus from the lingual surfaces of anterior teeth and concave surfaces between teeth at the cemento-enamel junction. | 2012-05-03 |
20120107771 | Removable Partial Dental Prosthesis - The present invention is a removable partial dental prosthesis comprised of a plastic framework. One or more acrylic prosthetic teeth are chemically bonded to the framework using dental acrylic. | 2012-05-03 |
20120107772 | MOUNTING STRUCTURE OF INTERNAL AND EXTERNAL CROWNS - A mounting structure is provided between internal and external crowns of a prosthetic device, in which a tenon-mortise type engagement is formed for fixing the crowns. The internal crown forms an internal coupling section and the external crown forms an external coupling section that corresponds to the internal coupling section. The external coupling section includes a liftable structure, whereby when the external crown is fit to the internal crown, the liftable structure is slightly bulged outward to allow for easy movement of the external crown for fitting to the internal crown. With the inter-engagement between the internal and external coupling sections, the external crown is set stably and securely on the internal crown and problems of insufficient or excessive fitting tightness between the crowns are eliminated or alleviated. | 2012-05-03 |
20120107773 | Fiber Abutment Material and Structure of Dental Implant - A fiber abutment material and structure of dental implant includes: a fiber resin abutment equipped with plural fiber center shafts, such as glass fiber center shaft, carbon fiber center shaft, quartz optical fiber center shaft, or glass fiber optics center shaft, in which the single, dual-layer or multi-layer fiber multiply enhances the intensity, and the fiber resin abutment with grind ability is easily modified on-site for the dentist, is equipped with considerable fibers with tensile strength higher than that of titanium or zirconia (ceramic), because of the fiber structure elasticity similar to natural tooth to be shock absorbed, to prevent the bone from hurting and decrease the damage to the base. | 2012-05-03 |
20120107774 | ZIRCONIUM OXIDE-BASED DENTAL IMPLANT AND METHOD FOR PRODUCING SAID DENTAL IMPLANT - A dental implant for a patient includes an anchoring part to anchor the dental implant in the bone and an abutment that is designed for fixation of a crown or similar supraconstruction and is or can be connected to the anchoring part. The anchoring part and the abutment are manufactured on a zirconium-oxide basis. The anchoring part and the abutment have special sections corresponding to the individual dimensions of the patient's bone and/or gums, said sections comprising a roughened surface designed to promote bone fusion. The special sections are produced on the green compact before the latter is finally sintered. | 2012-05-03 |
20120107775 | Methods of Using Botanical-Based Compositions to Treat Microbial Dental Disease - The present invention relates to methods of using botanical-based compositions to treat or prevent microbial dental disease. The claimed invention is directed to methods of using botanical-based compositions in a rinse, gel- or paste-like form to prevent microbe invasion of dental cavities, including the root canal. | 2012-05-03 |
20120107776 | TRAINING SYSTEM OF A POWERED VEHICLE - A training system for the solo operation of a powered vehicle, wherein the system includes: —providing means for electronic control of the speed and orientation of a ground vehicle or of the speed, orientation and height of a flying vehicle; —providing a virtual enclosure training area delineated by a plurality of spaced sensors; —providing means associated with said vehicle for communicating with, and receiving instructions from, each of said sensors; —whereby instructions received from said sensors may be used to control said means for electronic control such that movement of said vehicle is restricted to said virtual enclosure training area, and within said virtual enclosure training area, the speed and orientation of a ground vehicle or the speed, orientation and height of a flying vehicle controlled within preset parameters. | 2012-05-03 |
20120107777 | Methods For Generating Personalized Language Learning Lessons - Novel methods for generating language learning lessons. A learner is allowed to speak out loud a sentence in a foreign language while an instructor types down exactly how the sentence is spoken in a first column on a lesson sheet. The instructor then writes out a correct sentence marked with symbols noting the incorrect word and missing word in a second column parallel to the first column. Unfamiliar word is then placed in a third column and mispronounced word is placed in a fourth column. Words in third column and fourth column is further practiced in homework and in next lesson by using them to make new sentence by the learner. | 2012-05-03 |
20120107778 | INTERACTIVE DISPLAY BOARD AND METHOD FOR TEACHING SPEECH AND COMMUNICATION SKILLS USING SAID INTERACTIVE DISPLAY BOARD - The present invention is an interactive display board and method for teaching speech and communication skills through the interactive display board to an individual with language disabilities. A target response formed of sound units is requested from the individual. A plurality of visual indicators, such as lights, corresponds to each sound unit of the target response. The visual indicators are presented, and each sound unit is associated with a corresponding visual indicator. The association is a different sensory interaction, such a pressing a button, activating a switch, or pointing. The display board includes visual indicators with pressure-activated switches for the association of the sound units and visual indicators. The target response is the produced verbally by the individual concurrent with repeating the interaction with the visual indicators by the individual. | 2012-05-03 |
20120107779 | Object-field-based mathematics system - An apparatus includes a processor, a computer memory, a user interface, and computer-executable instructions which enable a user to formulate mathematical expressions via the user interface. The mathematical expression is composed from objects selected from a library of object types in the memory. The object types include primitive objects and non-primitive objects. Non-primitive objects contain at least one field which in turn can contain additional objects; primitive objects have no fields. The mathematical expression is defined by a computer-readable data structure in the memory, and each object and field has a mathematical significance assigned thereto. The data structure uniquely identifies each object and each field, and includes pointers to define nesting of the objects and fields in the mathematical expression. The computer-executable instructions include steps to identify user inputs with at least some of the objects, and to display the mathematical expression represented by the data structure via the display. | 2012-05-03 |
20120107780 | INSPECTION APPARATUS AND INSPECTION METHOD - An inspection apparatus includes: a display, a first display control section which displays, on the display, instructions for carrying out a plurality of inspection steps with the inspection apparatus, an evaluation section which performs an evaluation of a result of one of the inspection steps, a second display control section which displays, on the display, additional instructions for carrying out at least one additional inspection step; and, a control section which controls the second display control section to display the additional instructions in response to the evaluation section determining that said one of the inspection steps has not passed the evaluation. | 2012-05-03 |
20120107781 | Integrated Training System for Articles of Footwear - An integrated training system for articles of footwear is disclosed. Each article of footwear includes a set of physical characteristics associated with an athletic skill. A customized training program is provided with each article of footwear to provide custom tailored training for improving the particular athletic skill associated with the selected article of footwear. | 2012-05-03 |
20120107782 | Training device for martial artists and boxers - A trainer for a martial artist or boxer is provided comprising a container, a movable element positioned within container and a handle for grasping the trainer. The movable element produces an audible signal when it strikes a forward surface of the container and a muted audible signal or no audible signal when it strikes a rearward surface of the container. | 2012-05-03 |
20120107783 | AUTOMATIC INJECTION DEVICE - An automatic injection device for providing a subcutaneous injection is disclosed. The device includes a syringe movably disposed in a housing and including a barrel portion, a needle and a bung for sealing the barrel portion. The device includes a plunger for moving the syringe towards a first open end of the housing such that the needle projects from the first end, and for subsequently applying pressure to the bung. The plunger includes a rod connected at a first end to the bung, a compressible expanded central portion, and a flange between a second end of the rod and the central portion. The device also includes a biasing mechanism for biasing the plunger towards the first open end of the housing, the biasing mechanism disposed about the second end of the rod between the flange and a second end of the housing. | 2012-05-03 |
20120107784 | ONE TOUCH BUTTON FOR OPERATING ROOM SUPPORT - A method of obtaining assistance during a surgical procedure includes the steps of requesting assistance with a single action and establishing a line of communication between an individual in an operating room and an individual at a remote location in response to the step of requesting assistance. The method includes the steps of communicating a question to the individual at the remote location and receiving an answer to the question from the individual at the remote location. | 2012-05-03 |
20120107785 | PORTABLE KARAOKE SYSTEM, KARAOKE METHOD AND APPLICATION PROGRAM FOR THE SAME - A portable karaoke system, a karaoke method and an application program for the same are disclosed. The karaoke system comprises a receiving end karaoke apparatus and at least a transmitting end karaoke apparatus. The receiving end karaoke apparatus generates a song list to provide to the transmitting end karaoke apparatus according to songs internally saved and songs uploaded from transmitting end karaoke apparatus. The transmitting end karaoke apparatus transmits a selection command to receiving end karaoke apparatus for generating a play queue according to the song list. The receiving end karaoke apparatus plays the song files saved internally for generating music signals according to a play queue sequence. Lastly, the transmitting end karaoke apparatus receives external vocal signals and transmits the external vocal signals to the receiving end karaoke apparatus to perform audio mixing with the music signals. | 2012-05-03 |
20120107786 | METHOD OF CREATING A FOUNDATIONAL INSTRUCTIONAL DESIGN MODEL FOR SHAREABLE CONTENT OBJECTS - A method is provided for creating a foundational instructional design model for shareable content object (SCO) by pre-defining a semantically structured reusable learning type (RLT), and joining individual or repeated RLT's with sequence or choice indicators to form an instructional design model. The instructional design model is itself a semantically structured document that can be used and reused to create SCOs. | 2012-05-03 |
20120107787 | ADVISORY SERVICES NETWORK AND ARCHITECTURE - Systems and methods are provided to implement an advisory services network that enables organizations to identify complex business problems from apparent business problems, immerse a diverse group of people in the businesses of the organizations, and promote collaboration to develop viable solutions to the complex business problems. An enterprise organization can supply case studies of real-life scenarios, data, ethnographic interviews to convey multiple views of problematic areas, etc., to enable members of the diverse group of people to immerse themselves into the problem space, participate in creative communications, such as discussions, and brainstorm potential solutions. Further, the advisory services network can include a gaming platform on which instances of serious games can be developed and deployed. The serious games enables sharing of ideas among players, discussions among players, and other player interactions to facilitate compounding of perspectives and solutions among a diverse group while providing an entertaining and through-provoking environment. | 2012-05-03 |
20120107788 | Rhythmic learning method - The current invention offers experiences that might be called “simulated music reading.” This curriculum delivery invention comprises a computer-operated instructional delivery system displaying pre-formatted curriculum content accompanied by animations that elicit rhythmic participation. The computer-controlled display (computer monitor, television, or projection screen) provides access to start/stop and tempo controls. The display also reveals cursors, arrows, shadings, and other animated features applied to curriculum material, ensuring that students perceive a prescribed rhythm and can give a choral response. Whether reciting, interpreting, identifying, or supplying missing content elements, the students' creation of and involvement in a rhythmic context is a key element of the invention's efficacy. In summary, the invention presents curriculum content while encouraging rhythmic brain experiences that are known to develop general creativity and enhance performance abilities in reading, math, geometry, music, and other high demand cerebral challenges. | 2012-05-03 |
20120107789 | LEARNING ENVIRONMENT WITH USER DEFINED CONTENT - The invention relates to providing a computer based learning environment for a user wherein the user defines the content to be studied. The learning tool allows students to store and arrange located information in respect of a study topic, the material being in many different formats and from many sources, explore that located information, reinforce the material by testing their comprehension and understanding, allowing them to enquire further by expanding the information themselves or by collaboratively acquiring additional information/testing. The information/content to be studied by the user is established as a series of questions with answer, the format and content of each being determined by the user. In studying the invention allows the stored information to be displayed for a particular topic, whereas in testing the invention includes the further step of the user determining whether their answer to the question was correct. | 2012-05-03 |
20120107790 | APPARATUS AND METHOD FOR AUTHORING EXPERIENTIAL LEARNING CONTENT - A method of authoring experiential learning content includes displaying an authoring window to author the experiential learning content when a request is made to author the experiential learning content; and creating a virtual world by loading and arranging 3D objects and a 2D objects, in the authoring window, which corresponds to a scenario of the experiential learning content. Further, the method includes defining an Action-zone that determines a position where a user is merged in the virtual world; and defining a state by dividing the scenario into a plurality of steps as time goes by based on the scenario to play the experiential learning content from a specific time point, respectively. Furthermore, the method includes defining a processing routine of an event occurred in the state; and authoring the experiential learning content according to the defined Action-zone, the defined state, and the defined processing routine. | 2012-05-03 |
20120107791 | COMPOSITIONS AND METHODS FOR PROLONGING SURVIVAL OF PLATELETS - The present invention provides modified platelets having a reduced platelet clearance and methods for reducing platelet clearance. Also provided are compositions for the preservation of platelets. The invention also provides methods for making a pharmaceutical composition containing the modified platelets and for administering the pharmaceutical composition to a mammal to mediate hemostasis. | 2012-05-03 |
20120107792 | SYSTEMS AND METHODS FOR DELIVERY OF GASES TO ALGAL CULTURES - Photobioreactors according to embodiments of the present invention deliver nutrient gas intermittently to the photobioreactor media. In some embodiments, one or more gases are delivered according to a duty cycle or timing pattern. According to some embodiments, algae is grown in a photobioreactor using intermittent introduction of carbon dioxide. In other embodiments, carbon dioxide is supplied to algae grown in a photobioreactor in whole or in part from a head space above the media of the photobioreactor. | 2012-05-03 |
20120107793 | SAMPLE PROCESSING SYSTEM AND METHOD OF PROCESSING SAMPLE - A sample processing system comprising: a transporting device that transports a sample; a plurality of sample processing devices that are arranged along a transport path for the sample transported by the transporting device and configured to process the sample transported by the transporting device based on a processing order; a controller configured to receive a first processing order for the sample and control the transporting device to transport the sample based on the received first processing order, and configured to receive a second processing order for the sample additionally and control the transporting device to transport the sample based on the received second processing order; and a display, wherein the controller is configured to prompt the display to show progress information indicating a progress status of processing the sample with respect to each of the first and second processing orders. A method of processing sample in a sample processing system. | 2012-05-03 |
20120107794 | Cross-Coupled Peptide Nucleic Acids for Detection of Nucleic Acids of Pathogens - The present invention concerns methods for detecting a nucleic acid comprising (i) contacting a solution comprising a first PNA having a first cross-reactive functional group with a substrate having a second PNA affixed thereto, the second PNA having a second first cross-reactive functional group, wherein the first PNA has a reporter molecule attached thereto and the first and second PNAs being complementary to different portions of a target DNA; (ii) contacting a sample suspected of containing the nucleic acid with the first and second PNAs; and (iii) determining the presence of the reporter molecule on the substrate. | 2012-05-03 |
20120107795 | Methods For Concurrent Identification And Quantification Of An Unknown Bioagent - The present invention provides methods for the quantification of an unknown bioagent in a sample by amplification of nucleic acid of the bioagent, and concurrent amplification of a known quantity of a calibration polynucleotide from which are obtained a bioagent identifying amplicon and a calibration amplicon. Upon molecular mass analysis, mass and abundance data are obtained. The identity of the bioagent is then determined from the molecular mass of the bioagent identifying amplicon and the quantity of the identified bioagent in the sample is determined from the abundance data of the bioagent identifying amplicon and the abundance data of the calibration amplicon. | 2012-05-03 |
20120107796 | METHODS AND KITS TO DETECT NEW H1N1 "SWINE FLU" VARIANTS - Methods and kits used in the detection of the H1N1/09 influenza virus are disclosed. The methods comprise methods of using the nucleic acids to detect H1N1/09 generally as well as H1N1/09 variants resistant to antiviral compositions. | 2012-05-03 |
20120107797 | GENOTYPING OF BOVINE PAPILLOMAVIRUS GENOTYPES - The present invention is concerned with the provision of diagnostic means and methods. Specifically, it relates to a composition comprising oligonucleotides selected from at least two different groups of oligonucleotides, said groups comprising at least one pair of oligonucleotides being capable of specifically amplifying polynucleotides comprised by a Bovine Papillomavirus (BPV), said BPV being selected from the group consisting of BPV-1, BPV-2, BPV-3, BPV-4, BPV-5, BPV-6, BPV-7, BPV-8, BPV-9, BPV-10, and BAPV-11 as well as uses based on said composition and kits comprising it. Moreover, contemplated is a method for the simultaneous detection and/or identification of BPV types in a sample. | 2012-05-03 |
20120107798 | SINGLE MOLECULE SENSITIVE PROBES FOR DETECTING RNA - The various embodiments of the present disclosure relate generally to single molecule sensitive probes for detecting RNA, and more particularly to multivalent fluorescent probes for detecting a single molecule of RNA in a cell. The present invention includes a RNA imaging probe comprising: a multivalent core comprising a plurality of attachment sites; a plurality of RNA/DNA chimeric oligonucleotides having a specificity for a target RNA, wherein a RNA/DNA chimeric oligonucleotide is bound to an attachment site of the multivalent core; and a plurality of fluorophores, wherein a fluorophore is bound to the RNA/DNA chimeric oligonucleotide. | 2012-05-03 |
20120107799 | DISPOSABLE, RAPID EXTRACTION APPARATUS AND METHODS - An extraction apparatus and methods adapted to extract and preferably also isolate structures of interest from a test sample. The extraction apparatus contains a volume-dispensing mechanism that facilitates control over the injection of a sample suspected of containing a structure of interest into a filtration vessel that contains a membrane filter that associates with the structure of interest, preferably by adsorbing or binding thereto, and a collection container associated therewith. Methods of extracting, isolating, testing, and instructions regarding such methods are also included. | 2012-05-03 |
20120107800 | CELL-TARGETING NANOPARTICLES AND USES THEREOF - The invention generally refers to a cell-targeting nanoparticle, wherein the cell-targeting nanoparticle is directly conjugated to at least one cysteine-containing peptide, wherein the cysteine-containing peptide is selected from the group consisting of glutathione (GSM, a GSH-containing peptide, and a peptide comprising a nuclear localization signal (NLS) sequence and a transporter sequence, and methods of using the cell-targeting nanoparticle. | 2012-05-03 |
20120107801 | HIGH-EFFICIENCY HOMOLOGOUS RECOMBINATION IN THE OIL-PRODUCING ALGA, NANNOCHLOROPSIS - Transformation methods are provided for introducing deoxyribonucleic acid (DNA) into the nucleus of an algal cell. A transformation construct may be prepared, with the transformation construct having a first sequence of DNA similar to a corresponding first sequence of nuclear DNA, a second sequence of DNA similar to a corresponding second sequence of the nuclear DNA, and a sequence of DNA inserted between the first and second sequences of DNA of the transformation construct. A target sequence of DNA inserted between the first and second corresponding sequences of the nuclear DNA may be transformed, resulting result in replacement of the target sequence of DNA with the sequence of DNA of interest. | 2012-05-03 |
20120107802 | METHOD FOR SEQUENCING A HETEROPOLYMERIC TARGET NUCLEIC ACID SEQUENCE - The invention relates to a method for sequencing a heteropolymeric target nucleic acid sequence that involves stochastic sensing. The invention also relates to a method for improving a pore for sequencing a target nucleic acid sequence by modifying one or more sites in the pore. | 2012-05-03 |
20120107803 | METHOD FOR ENUMERATION OF MAMMALIAN MICRONUCLEATED ERYTHROCYTE POPULATIONS, WHILE DISTINGUISHING PLATELETS AND/OR PLATELET-ASSOCIATED AGGREGATES - A method for the enumeration of micronucleated erythrocyte populations while distinguishing platelet and platelet-associated aggregates involves the use of a first fluorescent labeled antibody having binding specificity for a surface marker for reticulocytes, a second fluorescent labeled antibody having binding specificity for a surface marker for platelets, and a nucleic acid staining dye that stains DNA (micronuclei) in erythrocyte populations. Because the fluorescent emission spectra of the first and second fluorescent labeled antibodies do not substantially overlap with one another or with the emission spectra of the nucleic acid staining dye, upon excitation of the labels and dye it is possible to detect the fluorescent emission and light scatter produced by the erythrocyte populations and platelets, and count the number of cells from one or more erythrocyte populations in said sample. In particular, the use of the second antibody prevents interference by platelet-associated aggregates in the scoring procedures. | 2012-05-03 |
20120107804 | DISINTEGRATION OF CELLULAR COMPONENTS IN BODY FLUIDS - The present invention refers to a method of processing a biological fluid which comprises cellular components by a freezing/thawing treatment. The method is particularly useful for preparing biological samples for analyte detection. | 2012-05-03 |
20120107805 | Generating a Fluid Stream in a Microfluidic Device - A fluid handling and delivery system useful in generating a fluid stream in the flow path of microfluidic device. | 2012-05-03 |
20120107806 | METHOD AND KITS FOR REPAIRING NUCLEIC ACID SEQUENCES - Methods and kits for DNA repair are provided. The methods and kits described herein repair multiple types of DNA damage. The kit may include a plurality of enzymes to repair a greater variety of lesions than any single enzyme is capable of repairing. Repair of damaged DNA may include releasing damaged bases from the DNA strand, nicking the DNA at the damaged sites, translating the nicks via 5′-3′ exonuclease activity, and sealing the nicks. The enzymes employed in the repair process may then be heat-inactivated, thereby obviating a purification process. The repaired DNA may then be analyzed using a variety of DNA analysis methods. | 2012-05-03 |
20120107807 | Highly sensitive method for the detection of cytosine methylation patterns - The present invention concerns a method for the detection of cytosine methylation in DNA samples, wherein the following steps are conducted: (a) a genomic DNA sample, which comprises the DNA to be investigated and background DNA, is chemically treated in such a way that all of the unmethylated cytosine bases are converted to uracil, whereas the 5-methylcytosine bases remain unchanged; (b) the chemically treated DNA sample is amplified with the use of at least 1 primer oligonucleotide as well as a polymerase, whereby the DNA to be investigated is preferred as the template over the background DNA, and (c) the amplified products are analyzed and the methylation status in the DNA to be investigated is concluded from the presence of an amplified product and/or from the analysis of additional positions. | 2012-05-03 |
20120107808 | High throughput detection of gene-specific hydroxymethylation - This invention provides a method for the detection of hydroxymethylation patterns in a DNA sample, especially in genetic regions. A test sample containing hydroxymethylated DNA is hybridized to capture oligonucleotides immobilized on a solid phase. The hydroxymethylated DNA in hybrid is detected using an antibody which specifically recognizes hydroxymethylcytosine structure the marker of DNA hydroxymethylation-followed by immuno-signal amplification. The present invention provides a method to detect gene-specific hydroxymethylation in a simple, rapid and high throughput format with high specificity and sensitivity. | 2012-05-03 |
20120107809 | METHOD FOR SIMULTANEOUSLY DETECTING HISTOPLASMA CAPSULATUM AND PARACOCCIDIOIDES BRASILIENSIS - The present invention relates to a method for simultaneously detecting DNA of | 2012-05-03 |
20120107810 | Epigenetic Markers for the Identification of Blood Sub-Cells of Type 1 - The present invention relates to a method, in particular an in vitro method, for identifying CD3CD4 positive T lymphocytes of a mammal, wherein said method comprises analysing the methylation status of at least one CpG position in the CD3a/b/c/d/g genes, in particular their “upstream” regulatory regions, and in particular the promoter and other conserved regions of the gene cd3, wherein a demethylation of at least one CpG in the analyzed sample to at least 90% is indicative for memory and naive CD4 or/and memory and/or native T lymphocytes. Furthermore, the present invention is directed at the use of DNA-methylation analysis of the genes CD3a/b/c/d for the detection and quality assurance and control of T lymphocytes. Furthermore, the present invention relates to a kit for performing the above methods as well as respective uses thereof. In a preferred embodiment, the present invention furthermore provides an improved method for analysing the methylation status of at least one CpG position in the gene CD3, allowing for a precise analysis even from sub-optimal quality samples, such as non-freshly obtained blood or serum samples. | 2012-05-03 |
20120107811 | BURSTABLE LIQUID PACKAGING AND USES THEREOF - The present invention relates to systems, devices, and methods for performing biological and chemical reactions. In particular, the present invention relates to the use of burstable liquid packaging for delivery of reagents to biological and chemical assays. | 2012-05-03 |
20120107812 | Means and methods for investigating nucleic acid sequences - The invention provides improved methods for investigating nucleic acid sequences, wherein at least one additional probe is used which is specific for a (pseudo)gene variant of a target nucleic acid. The invention further provides improved calibrators which are particularly suitable for determining (pseudo)gene variants and copy number variation. | 2012-05-03 |
20120107813 | QUANTIFICATION OF NUCLEIC ACIDS - The invention relates to a method for the quantification of one or more nucleic acids in a sample. The method comprises the following steps: making a sample available which contains at least one nucleic acid to be quantified, adding an oligonucleotide probe to the sample, the oligonucleotide probe comprising a sequence which can specifically hybridize to the nucleic acid to be quantified or to a common sequence of the nucleic acids to be quantified, incubating the sample under conditions which allow the hybridization of the oligonucleotide probe to the nucleic acid(s) to be quantified, incubating the sample under conditions which allow the extension of hybridized probes, the nucleic acid(s) serving as a template in each case, removing the non-hybridized probes from the sample and quantifying the hybridized oligonucleotide probes to measure the quantity of the nucleic acid(s) to be quantified. The invention also relates to a kit for carrying out said method. | 2012-05-03 |
20120107814 | Method for Determining the Predisposition of a Patient to Changed Biotransformation and to the Development of Undesired Drug Effects in a Treatment of the Patient with Atrovastatin - A method for determining a predisposition of a patient to the development of muscular diseases and/or to changed biotransformation in a treatment of the patient with atorvastatin is disclosed. The presence of at least one single nucleotide polymorphism (SNP) in the UGT1A3 gene (uridine diphosphate glucuronosyltransferase gene 1A3) and/or an increased UGT1A3 gene expression is determined in a biological sample of the patient. The disclosure further relates to oligonucleotides that can be used in the method and to diagnostic kits that use the oligonucleotides. | 2012-05-03 |
20120107815 | Polymorphism Detection Probe, Polymorphism Detection Method, Evaluation of Drug Efficacy, and Polymorphism Detection Kit - The invention provides a probe which detects a polymorphism in the MDR1 gene. The probe has a P1 and/or a P2 oligonucleotide. The P1 oligonucleotide has a sequence that is complementary to a first base sequence, in which the first base sequence is a partial sequence of SEQ ID NO: 2 having a length of from 13 bases to 68 bases and including the 288th to 300th bases of SEQ ID NO: 2. The base complementary to the 288th base is labeled with a fluorescent dye. The P2 oligonucleotide has a sequence that is complementary to a second base sequence, in which the second base sequence is a partial sequence of SEQ ID NO: 2 having a length of from 6 bases to 93 bases and including the 300th to 305th bases of SEQ ID NO: 2. The base complementary to the 305th base is labeled with a fluorescent dye. | 2012-05-03 |